Weekly Influenza & Respiratory
Illness Activity Report
A summary of influenza surveillance indicators prepared by the Division of Infectious Disease Epidemiology Prevention & Control
Week Ending November 12, 2016 | WEEK 45
All data are preliminary and may change as more information is received
Minnesota Influenza Geographic Spread
No Activity
Sporadic
Local
Regional
Widespread
During the week ending November 12, 2016 (Week 45),
surveillance indicators showed
sporadic geographic spread of influenza.
Since the start of the influenza season,
0 pediatric influenza-related deaths
have been reported.
Based on CDC’s Activity Estimates Definitions: http://www.cdc.gov/flu/weekly/overview.htm
Minnesota Influenza Surveillance:
http://www.health.state.mn.us/divs/idepc/diseases/flu/stats/
Weekly U.S. Influenza Surveillance Report:
http://www.cdc.gov/flu/weekly/
World Health Organization (WHO) Surveillance: http://www.who.int/influenza/surveillance_monitoring/updates/en/
Neighboring states’ influenza information:
Iowa
http://www.idph.state.ia.us/IdphArchive/Archive.aspx?channel=FluReports
Wisconsin
http://www.dhs.wisconsin.gov/communicable/influenza/surveillance.htm
North Dakota http://www.ndflu.com/default.aspx
South Dakota http://doh.sd.gov/diseases/infectious/flu/
Minnesota Department of Health
651-201-5414 or 1-877-676-5414
www.health.state.mn.us
11/17/2016
Hospitalized Influenza Surveillance
Hospitalized influenza cases are based on disease reports of laboratory-positive influenza (via DFA, IFA, viral culture, EIA, rapid test, paired
serological tests or RT-PCR) and specimens from hospitalized patients with acute respiratory illness submitted to MDH-PHL by hospitals and
laboratories. Due to the need to confirm reports and reporting delays, consider current week data preliminary.
Hospitalized Influenza Cases by Type
Minnesota (FluSurv-NET*)
B (no genotype)
45
B (Yamagata)
40
A (not subtyped)
B (Victoria)
A H3
35
A H1 (unspecified)
A (H1N1)pdm09
30
A (H1N2v)
A (H3N2v)
25
A&B
20
Unknown
Current week
15
10
Number of Hospitalizations
Number of Hospitalizations
50
Hospitalized Influenza Cases by Season, Minnesota
(FluSurv-NET*)
750
700
650
600
550
500
450
400
350
300
250
200
150
100
50
0
2011-12
2012-13
2013-14
2014-15
2015-16
2016-17
Current week
40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20
MMWR Week
5
0
40 42 44 46 48 50 52 2
4
6
8 10 12 14 16 18 20
MMWR Week
Hospitalizations
this week
Hospitalizations
last week
Total hospitalizations
(to date)
2
3
16
*Influenza Surveillance Network
Season
2011-2012
2012-2013
2013-2014
2014-2015
2015-2016
2016-2017
Total hospitalizations
(historic)
556
3,068
1,540
4,138
1,541
16 (to date)
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
2
Hospitalized Influenza Surveillance (continued)
Number of Hospitalizations
Incidence (cases) per
100,000 Persons
16
1.80
1.60
14
1.40
12
1.20
10
1.00
0.8
8
6
4
2
0.80
0.60
0.4
0.1
0
0.40
0.0
0.0
0.0
0.0
0.0
0.20
0.00
20
18
1.8
1.6
14
1.4
12
1.2
10
1.0
8
0.8
6
0.6
4
2
0.2
0.0
0.0
0-4
5-24
0.4
0.2
25-49
50-64
0.2
65+
0.0
Age Group (years)
Region
Central
Metro
Northeast
Northwest
South Central
Southeast
Southwest
West Central
1.6
Incidence (cases) per
100,000 Persons
16
0
Region
2.0
# of hospitalizations
Hospitalizations per 100,000 Persons
18
2.00
Hospitalizations per 100,000 Persons
# of hospitalizations
20
Number of Influenza Hospitalizations and Incidence by
Age, Minnesota
October 2, 2016 – November 12, 2016
Number of Hospitalizations
Number of Influenza Hospitalizations and Incidence by
Region, Minnesota
October 2, 2016 – November 12, 2016
Hospitalizations
this week
Total
(to date)
0 (0%)
2 (100%)
0 (0%)
0 (0%)
0 (0%)
0 (0%)
0 (0%)
0 (0%)
1 (6%)
11 (69%)
0 (0%)
0 (0%)
0 (0%)
4 (25%)
0 (0%)
0 (0%)
Median age (years)
at time of admission
72.0
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
3
Respiratory Disease Outbreak Surveillance
School Outbreaks
K-12 schools report an outbreak of influenza-like illness (ILI) when the number of students absent with ILI reaches 5% of total enrollment or
three or more students with ILI are absent from the same elementary classroom.
Number of influenza-like illness outbreaks
Influenza-like Illness (ILI) in Schools by Season
300
2012-13
2013-14
2014-15
250
2015-16
2016-17
200
150
100
Current week
50
0
40 41 42 43 44 45 46 47 48 49 50 51 52 1
2
3
4
5
6
7
8
9 10 11 12 13 14 15 16 17 18 19 20 21
MMWR Week
New school
outbreaks this week
New school
outbreaks last week
Total this season
(to date)
3
1
7
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
4
Respiratory Disease Outbreak Surveillance (continued)
Long-Term Care (LTC) Outbreaks
LTC facilities report to MDH when they suspect an outbreak of influenza in their facility. Laboratory-confirmed outbreaks are reported here.
Confirmed Influenza Outbreaks in LTC by Season
70
Number of lab-confirmed outbreaks
65
2012-13
60
2013-14
55
2014-15
50
2015-16
45
2016-17
40
35
30
25
20
Current week
15
10
5
0
40 41 42 43 44 45 46 47 48 49 50 51 52 1
2
3
4
5
6
7
8
9 10 11 12 13 14 15 16 17 18 19 20 21
MMWR Week
New LTC outbreaks
this week
New LTC outbreaks
last week
Total this season
(to date)
1
0
1
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
5
Sentinel Provider Surveillance (Outpatients)
MDH collaborates with healthcare providers who report the total number of patients seen and the total number of those patients presenting to
outpatient clinics with influenza-like illness.
Percentage of Persons Presenting to Outpatient Clinics with Influenza-Like Illness (ILI)
9
2012-13
Percent with Influenza-like Illness
8
2013-14
2014-15
7
2015-16
6
2016-17
5
4
3
Current week*
2
1
0
40 41 42 43 44 45 46 47 48 49 50 51 52 1
2
3
4
5
6
7
8
9 10 11 12 13 14 15 16 17 18 19 20 21
MMWR Week
% of outpatients with
ILI this week
% of outpatients with
ILI last week
0.3%
0.9%
*Indicates current week-data may be
delayed by 1 or more weeks
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
6
Laboratory Surveillance
The MN Lab System (MLS) Laboratory Influenza Surveillance Program is made up of more than 310 clinic- and hospital-based laboratories,
voluntarily submitting testing data weekly. These laboratories perform rapid testing for influenza and Respiratory Syncytial Virus (RSV).
Significantly fewer labs perform PCR testing for influenza and three also perform PCR testing for other respiratory viruses. MDH-PHL provides
further characterization of submitted influenza isolates to determine the hemagglutinin serotype to indicate vaccine coverage. Tracking the
laboratory results assists healthcare providers with patient diagnosis of influenza-like illness and provides an indicator of the progression of the
influenza season as well as prevalence of disease in the community.
Specimens Positive for Influenza by Molecular Testing*, by Week
25
B
A H3
20
A (H1N1) pdm09
2013-14 % + by PCR
15
2014-15 % + by PCR
2015-16 % + by PCR
10
2016-17 % + by PCR
Current week
30
25
20
15
10
5
0
5
40 41 42 43 44 45 46 47 48 49 50 51 52 1
2
3
4
5
6
7
8
9 10 11 12 13 14 15 16 17 18 19 20 21
MMWR Week
% molecular tests
positive this week
% molecular tests
positive last week
0.84%
0.48%
Percent of positive molecular tests
Number of positive molecular tests
A (not subtyped)
35
0
*Beginning in 2016-17, laboratories report
results for rapid molecular influenza tests
in addition to RT-PCR results
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
7
Laboratory Surveillance (continued)
MLS Laboratories – Influenza Testing
MLS Laboratories – RSV Testing
Specimens Positive by Influenza Rapid Antigen Test, by Week
Specimens Positive by RSV Rapid Antigen Test, by Week
Number of Positive Influenza Specimens
60
50
40
2013-14 % +
45
2014-15% +
40
2015-16 % +
35
2016-17 % +
30
25
Current week
20
30
15
20
10
10
0
5
40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20
MMWR Week
Region
Northeast
South Central
Southwest
Southeast
Metro
Central
West Central
Northwest
State (overall)
0
% rapid antigen influenza tests +
(current week)
3%
0%
5%
8%
2%
0%
0%
0%
2%
50
Number +
45
2013-14 % +
40
2014-15 % +
35
2015-16 % +
2016-17 % +
30
25
Current week
20
15
10
5
0
40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20
MMWR Week
Region
Northeast
South Central
Southwest
Southeast
Metro
Central
West Central
Northwest
State (overall)
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
Percentage of Rapid Antigen RSV Tests Positive
70
A/B+ (2015-16 Season)
50
Percentage of Rapid Antigen Influenza Tests Positive
A+ (2015-16 Season)
80
Number of Positive RSV Tests
B+ (2015-16 Season)
% rapid antigen RSV tests +
(current week)
12%
0%
0%
13%
20%
14%
0%
8%
13%
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
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Laboratory Surveillance (continued)
Minnesota Influenza Incidence Surveillance Project (MIISP)
Positive Respiratory Pathogens by PCR, by MMWR Week
Number Positive by RT-PCR
20
Influenza B
Influenza A H3
Influenza A (H1N1) pdm09
Influenza A Unspecified
Influenza C
RSV
Human Metapneumovirus
Rhinovirus/Enterovirus
Adenovirus
Coronavirus NL63
Coronavirus OC43
Coronavirus 229E
Coronavirus HKU1
Parainfluenza-1
Parainfluenza-2
Parainfluenza-3
Parainfluenza-4
15
10
5
0
30
32
34
36
38
40
42
44
46
48
50
52 1 2
4
6
8
10
12
14
16
18
20
MMWR Week*
*Indicates current week-data may be delayed by 2 or more weeks
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
9
Laboratory Surveillance (continued)
Severe Acute Respiratory Surveillance (SARI) - Inpatients
Positive Respiratory Pathogens by PCR, by MMWR Week
Parainfluenza 4
Parainfluenza 3
Parainfluenza 2
Parainfluenza 1
Coronavirus HKU1
75
Coronavirus 229E
Coronavirus OC43
Coronavirus NL63
Adenovirus
Rhinovirus/Enterovirus
70
Human Metapneumovirus
RSV
Influenza A Unspecified
Influenza A (H1N1) pdm09
Influenza A H3
Influenza B
Legionella
Mycoplasma pneumoniae
Chlamydophila pneumoniae
Bordetella pertussis
65
Bocavirus
Number Positive by RT-PCR
60
55
50
45
40
35
30
25
20
15
10
5
0
32
34
36
38
40
42
44
46
48
50
52
2
4
6
8
10
12
14
16
18
20
20
MMWR Week*
*Indicates current week-data may be delayed by 2 or more weeks
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
10
Weekly U.S. Influenza Surveillance Report
2016-2017 Influenza Season Week 44 ending November 5, 2016
National Influenza Surveillance (CDC): http://www.cdc.gov/flu/weekly/
Viral Surveillance: The most frequently identified influenza virus subtype reported by public health laboratories during week 44 was influenza A (H3). The percentage of
respiratory specimens testing positive for influenza in clinical laboratories increased slightly but remained low.
Pneumonia and Influenza Mortality: The proportion of deaths attributed to pneumonia and influenza (P&I) was below the system-specific epidemic threshold in the National
Center for Health Statistics (NCHS) Mortality Surveillance System.
Influenza-associated Pediatric Deaths: No influenza-associated pediatric deaths were reported.
Outpatient Illness Surveillance: The proportion of outpatient visits for influenza-like illness (ILI) was 1.4%, which is below the national baseline of 2.2%. All 10 regions
reported ILI below region-specific baseline levels. Puerto Rico experienced moderate ILI activity, one state experienced low ILI activity, New York City and 49 states
experienced minimal ILI activity, and the District of Columbia had insufficient data.
Geographic Spread of Influenza: The geographic spread of influenza in Guam, Puerto Rico, and one state was reported as regional; six states reported local activity; the
District of Columbia, the U.S. Virgin Islands and 39 states reported sporadic activity; and four states reported no activity.
Minnesota Department of Health Weekly Influenza & Respiratory Activity Report for Week Ending November 12, 2016 | WEEK 45
11