MINNESOTA DEPARTMENT OF HEALTH
EMERGING INFECTIONS PROGRAM
REPORTED CASES OF INVASIVE BACTERIAL DISEASE
JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/200112/31/2001
Rate per
No. 100,000*
PATHOGEN
Neisseria meningitidis
Serogroup B
Serogroup C
Serogroup Y
Serogroup W135
Serogroup X
Not groupable
Reported but isolate not
available
Haemophilus influenzae
type a
type b
type c
type d
type e
type f
Non-typeable
Reported but isolate not
available
27
1/1/200212/31/2002
Rate per
No. 100,000*
0.55
9
11
7
0
0
0
8
17
9
1
1
0
0
0
56
1.14
2
1
0
4
1
6
23
2
1
1
2
4
11
22
19
9
36
0.73
52
1.06
Group A streptococcus
200
4.07
147
2.99
Group B streptococcus
273
5.55
312
6.34
339
13.89
300
598
12.29
12.16
Streptococcus pneumoniae†
2001, Twin Cities
Metropolitan area only
2002, Statewide
*Annual rate using populations from the U.S. Bureau of the Census 2000
†Cases reported among residents and from hospitals in the seven-county metropolitan area where
reporting of all cases of S. pneumoniae disease is required during 2001.
Note: In 2002, S. pneumoniae is reported statewide.
Note:
Active surveillance for these pathogens began April 1, 1995. Previous reports have
summarized data for 4/1/95-12/31/01. This current report can also be located via
the MDH Web Page at: www.health.state.mn.us
MDH Emerging Infections Program (612) 676-5414
TABLE 2
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
NEISSERIA MENINGITIDIS , JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/200112/31/2001
1/1/200212/31/2002
1/1/200112/31/2001
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No. (%)
14 (52)
13 (48)
27 (100)
OUTCOME
No. (%)
8 (22)
28 (78)
36 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60+
TOTAL
Survived
Yes
No
TOTAL
No. (%)
23 (85)
4 (15)
27 (100)
No. (%)
2
(7)
3 (11)
0
(0)
6 (22)
6 (22)
1
(4)
4 (15)
2
(7)
3 (11)
27 (100)
No. (%)
5 (14)
6 (17)
2
(6)
5 (14)
3
(8)
1
(3)
3
(8)
1
(3)
10 (28)
36 (100)
No. (%)
9 (33)
18 (67)
27 (100)
No. (%)
17 (47)
19 (53)
36 (100)
Site
Blood only
CSF only
Blood and CSF
Other
TOTAL
No.
21
2
No. (%)
18 (67)
9 (33)
0
(0)
0
(0)
27 (100)
No. (%)
22 (61)
13 (36)
0
(0)
1
(3)
36 (100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Septic arthritis
Pericarditis
Otitis
Other
TOTAL
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
Other/Unknown
TOTAL
No. (%)
31 (86)
5 (14)
36 (100)
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200212/31/2002
No. (%)
9 (33)
11 (41)
3 (11)
3 (11)
0
(0)
0
(0)
1
(4)
27 (100)
No. (%)
17 (47)
16 (44)
3
(8)
0
(0)
0
(0)
0
(0)
0
(0)
36 (100)
SEROGROUP
(%)
(78)
(7)
0
(0)
0
(0)
4 (15)
27 (100)
No.
15
2
(%)
(42)
(6)
1
(3)
0
(0)
18 (50)
36 (100)
Serogroup
B
C
Y
W135
X
Not groupable
Unknown
TOTAL
No. (%)
9 (33)
11 (41)
7 (26)
0
(0)
0
(0)
0
(0)
0
(0)
27 (100)
No. (%)
8 (22)
17 (47)
9 (25)
1
(3)
1
(3)
0
(0)
0
(0)
36 (100)
Cases of Neisseria meningitidis Invasive
Disease by Culture Date, Minnesota
January 1, 2001 - December 31, 2002
Serogroup B
Serogroup C
Serogroup Y
Serogroup W135
Number of Cases
12
Serogroup X
10
Not Groupable/Unk
8
Death
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2001
2002
Month of Culture
TABLE 3
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/200112/31/2001
1/1/200212/31/2002
1/1/200112/31/2001
OUTCOME
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
(%)
27 (48)
29 (52)
56 (100)
No.
(%)
24 (46)
28 (54)
52 (100)
Survived
Yes
No
TOTAL
No.
(%)
44 (79)
12 (21)
56 (100)
No.
(%)
49 (94)
3
(6)
52 (100)
SITE OF ISOLATE CULTURE
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
1/1/200212/31/2002
No.
(%)
3
(5)
4
(7)
3
(5)
0
(0)
2
(4)
2
(4)
3
(5)
7 (13)
8 (14)
24 (43)
56 (100)
No.
(%)
8 (15)
0
(0)
1
(2)
3
(6)
4
(8)
2
(4)
0
(0)
11 (21)
4
(8)
19 (37)
52 (100)
Site
Blood only
CSF only
Peritoneal
Joint
Amniotic fluid/Placenta
Pleural fluid
Surgical Aspirate
Other
TOTAL
No.
(%)
43 (77)
4
(7)
2
(4)
0
(0)
0
(0)
1
(2)
5
(9)
1
(2)
56 (100)
No.
(%)
41 (79)
4
(8)
0
(0)
2
(4)
0
(0)
2
(4)
1
(2)
2
(4)
52 (100)
GENDER
Gender
Male
Female
TOTAL
No.
(%)
28 (50)
28 (50)
56 (100)
No.
(%)
31 (60)
21 (40)
52 (100)
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
Other/Unknown
TOTAL
No.
32
2
(%)
(57)
(4)
2
(4)
3
(5)
17 (30)
56 (100)
No.
24
4
(%)
(46)
(8)
3
(6)
1
(2)
20 (38)
52 (100)
TYPE OF INFECTION
Type
Bacteremia
Pneumonia
Meningitis
Cellulitis
Peritonitis
Epiglottitis
Chorioamnionitis
Arthritis
Septic abortion
Sinusitis
Other
TOTAL
No.
(%)
22 (39)
19 (34)
4
(7)
1
(2)
0
(0)
1
(2)
0
(0)
0
(0)
0
(0)
1
(2)
8 (14)
56 (100)
No.
(%)
17 (33)
17 (33)
7 (13)
1
(2)
0
(0)
1
(2)
0
(0)
1
(2)
0
(0)
0
(0)
8 (15)
52 (100)
Cases of Haemophilus influenzae Invasive
Disease by Culture Date, Minnesota
January 1, 2001 - December 31, 2002
Type b
Number of Cases
12
Death
10
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2001
2002
Month of Culture
TABLE 4
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/0112/31/2001
RESIDENCE
Residence
No. (%)
Twin Cities Metro Area
118 (59)
Greater Minnesota
82 (41)
TOTAL
200 (100)
1/1/0212/31/2002
No. (%)
82 (56)
65 (44)
147 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No. (%)
5
(3)
8
(4)
13
(7)
9
(5)
17
(9)
27 (14)
36 (18)
17
(9)
17
(9)
51 (26)
200 (100)
No. (%)
2
(1)
6
(4)
7
(5)
10
(7)
6
(4)
11
(7)
19 (13)
19 (13)
23 (16)
44 (30)
147 (100)
GENDER
Gender
Male
Female
TOTAL
No. (%)
109 (55)
91 (46)
200 (100)
No. (%)
73 (50)
74 (50)
147 (100)
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
Other/Unknown
TOTAL
No.
118
13
(%)
(59)
(7)
12
(6)
5
(3)
52 (26)
200 (100)
No.
99
5
(%)
(67)
(3)
5
(3)
1
(1)
37 (25)
147 (100)
1/1/0112/31/2001
1/1/0212/31/2002
SITE OF ISOLATE CULTURE
Site
No. (%)
No. (%)
Blood only
90 (45)
92 (63)
CSF only
1
(1)
1
(1)
Blood and other
13
(7)
5
(3)
Joint
26 (13)
11
(7)
Surgical specimen
39 (20)
7
(5)
Peritoneal
3
(2)
2
(1)
Pleural
5
(3)
5
(3)
Middle ear
0
(0)
1
(1)
Bone
0
(0)
0
(0)
Surgical Aspirate
18
(9)
5
(3)
Muscle
0
0
8
(5)
Internal Body Site
0
0
1
(1)
5
(3)
9
(6)
Other sterile site
TOTAL
200 (100) 147 (100)
TYPE OF INFECTION
Type
No. (%)
Bacteremia only
37 (19)
Meningitis
2
(1)
Pneumonia only
16
(8)
Cellulitis only
47 (24)
Necrotizing fasciitis
(NF) only
11
(6)
Peritonitis
2
(1)
Arthritis only
9
(5)
Osteomyelitis
7
(4)
Endometritis
1
(1)
Abscess
11
(6)
Otitis Media
0
(0)
Peurperal Sepsis
0
(0)
STSS
1
(1)
Pneumonia + other
4
(2)
NF + other
6
(3)
Cellulitis + other
8
(4)
Abscess + other
1
(1)
Other
37 (19)
TOTAL
200 (100)
No.
30
1
10
36
(%)
(20)
(1)
(7)
(24)
8
(5)
1
(1)
7
(5)
1
(1)
2
(1)
9
(6)
2
(1)
1
(1)
4
(3)
3
(2)
5
(3)
10
(7)
3
(2)
14 (10)
147 (100)
TABLE 4 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/0112/31/2001
1/1/0212/31/2002
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
185
15
0
200
(%)
(93)
(8)
(0)
(100)
No.
123
24
0
147
(%)
(84)
(16)
(0)
(100)
No.
4
0
3
4
1
2
4
0
1
1
0
2
0
1
1
24
(%)
(17)
(0)
(13)
(17)
(4)
(8)
(17)
(0)
(4)
(4)
(0)
(8)
(0)
(4)
(4)
(100)
TYPE OF INFECTION
RESULTING IN DEATH
Type
Bacteremia
Meningitis
Necrotizing fasciitis
Pneumonia
Abscess
STSS
Cellulitis
Peritonitis
Peurperal Sepsis
Septic Arthritis
Pneumonia + Cellulitis
NF + Cellulitis
Pneumonia + STSS
NF + STSS
Cellulitis + STSS
TOTAL
No.
4
0
3
2
0
0
2
0
0
1
1
1
0
1
0
15
(%)
(27)
(0)
(20)
(13)
(0)
(0)
(13)
(0)
(0)
(7)
(7)
(7)
(0)
(7)
(0)
(100)
Cases of Invasive Group A Streptococcal Disease
by Date of Culture, Minnesota
January 1, 2001 – December 31, 2002
Death
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec
2001
2002
Date of Culture
TABLE 5
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/20011/1/200212/31/2001 12/31/2002
1/1/20011/1/200212/31/2001 12/31/2002
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
OUTCOME
No. (%)
143 (52)
130 (48)
273 (100)
No. (%)
188 (60)
125 (40)
313 (100)
AGE
Age
<7 days
7-90 days
91 days-11 mos.
1-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No. (%)
27
(9)
18
(6)
2
(1)
0
(0)
5
(2)
15
(5)
20
(6)
35 (11)
37 (12)
57 (18)
97 (31)
313 (100)
GENDER
No. (%)
155 (57)
118 (43)
273 (100)
No.
174
18
No. (%)
289 (92)
24
(8)
313 (100)
Site
Blood only
CSF only
Blood and CSF
Pleural
Joint
Placenta
Surgical Specimen
Peritoneal
Bone
Other
TOTAL
No. (%)
196 (72)
11
(4)
2
(1)
2 (<1)
23
(8)
6
(2)
15
(5)
6
(2)
12
(4)
0
(0)
273 (100)
No. (%)
241 (77)
13
(4)
0
(0)
3
(1)
22
(7)
8
(3)
1
(0)
8
(3)
17
(5)
0
(0)
313 (100)
TYPE OF INFECTION
No. (%)
167 (53)
146 (47)
313 (100)
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
Other/Unknown
TOTAL
No. (%)
254 (93)
19
(7)
273 (100)
SITE OF ISOLATE CULTURE
No. (%)
22
(8)
17
(6)
6
(2)
3 (<1)
5
(2)
14
(5)
20
(7)
35 (13)
41 (15)
33 (12)
77 (28)
273 (100)
Gender
Male
Female
TOTAL
Survived
Yes
No
TOTAL
(%)
(64)
(7)
6
(2)
7
(0)
68 (25)
273 (100)
No.
181
22
(%)
(58)
(7)
6
(2)
6
(2)
98 (31)
313 (100)
Type
Bacteremia
Meningitis
Pneumonia
Cellulitis
Arthritis
Osteomyelitis
Abscess
Necrotizing fasciitis
Peritonitis
Septic abortion
or stillbirth
Other
TOTAL
No.
118
15
14
34
22
16
9
1
5
6
(%)
(43)
(5)
(5)
(12)
(8)
(6)
(3)
(0)
(2)
(2)
33 (12)
273 (100)
No.
139
9
24
46
20
13
10
3
8
6
(%)
(44)
(3)
(8)
(15)
(6)
(4)
(3)
(1)
(3)
(2)
35 (11)
313 (100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2001 - DECEMBER 31, 2002
EARLY ONSET CASES*
1/1/200112/31/2001
LATE ONSET CASES*
1/1/200212/31/2002
1/1/200112/31/2001
1/1/200212/31/2002
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
14
8
22
(%)
(64)
(36)
(100)
No.
19
8
27
(%)
(70)
(30)
(100)
No.
9
8
17
(%)
(53)
(47)
(100)
No.
11
7
18
(%)
(61)
(39)
(100)
No.
11
6
17
(%)
(65)
(35)
(100)
No.
8
10
18
(%)
(44)
(56)
(100)
GENDER
Gender
Male
Female
TOTAL
No.
12
10
22
(%)
(55)
(45)
(100)
No.
11
16
27
(%)
(41)
(59)
(100)
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
Unknown
TOTAL
No.
14
1
(%)
(64)
(5)
No.
21
1
(%)
(78)
(4)
No.
7
8
(%)
(41)
(47)
No.
13
5
(%)
(72)
(28)
0
3
4
22
(0)
(14)
(18)
(100)
2
2
1
27
(7)
(7)
(4)
(100)
0
1
1
17
(0)
(6)
(6)
(100)
0
0
0
18
(0)
(0)
(0)
(100)
No.
15
2
17
(%)
(88)
(12)
(100)
No.
17
1
18
(%)
(94)
(6)
(100)
(%)
(53)
(29)
(0)
(18)
(100)
No.
13
4
0
1
18
(%)
(72)
(22)
(0)
(6)
(100)
OUTCOME
Survived
Yes
No
TOTAL
No.
19
3
22
(%)
(86)
(14)
(100)
No.
26
1
27
(%)
(96)
(4)
(100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Other
TOTAL
No.
18
2
1
1
22
(%)
(82)
(9)
(5)
(5)
(100)
No.
18
1
4
4
27
(%)
(67)
(4)
(15)
(15)
(100)
No.
9
5
0
3
17
* Early onset is defined as occurring in the first 6 days, and late onset in the 7th-90th days of life.
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/200112/31/2001
1/1/200212/31/2002
TYPE OF CASE
Type of Case*
Maternal case with miscarriage/
stillbirth
Other maternal case
Infant case - early onset
Infant case - late onset
Not pregnant/postpartum/infant case
TOTAL
No.
(%)
No.
(%)
8
6
22
17
220
273
(3)
(2)
(8)
(6)
(81)
(100)
8
6
27
18
254
313
(3)
(2)
(9)
(6)
(81)
(100)
*A maternal case is defined as invasive GBS infection during pregnancy or postpartum. An early onset infant
case is defined as invasive disease occurring in the first 6 days, and late onset in the 7th - 90th days of life.
TYPE OF INFECTION REPORTED FOR MATERNAL CASES
Type
Bacteremia without another
focus of infection
Septic abortion/ stillbirth
Meningitis
Chorioamnionitis
Abscess
Pyelonenephritis
Unknown
Bleeding on ultrasound
TOTAL
No.
(%)
No.
(%)
3
7
1
2
1
0
0
0
14
(21)
(50)
(7)
(14)
(7)
(0)
(0)
(0)
(100)
1
8
0
1
0
1
2
1
14
(7)
(57)
(0)
(7)
(0)
(7)
(14)
(7)
(100)
OUTCOME OF FETUS FOR MATERNAL CASES
Outcome
Survived, no apparent clinical illness
Survived, clinical infection
Live birth, neonatal death-GBS related
Miscarriage/stillbirth-likely
GBS-related
Induced abortion
TOTAL
No.
3
2
1
(%)
(21)
(14)
(7)
No.
4
1
0
(%)
(29)
(7)
(0)
8
0
14
(57)
(0)
(100)
8
1
14
(57)
(7)
(100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2001 - DECEMBER 31, 2002
1/1/200112/31/2001
1/1/200212/31/2002
SITE OF ISOLATE CULTURE FOR MISCARRIAGES/STILLBIRTHS
Site
Maternal blood
Amniotic fluid
Placenta only
Autopsy only
TOTAL
No.
0
1
6
1
8
(%)
(0)
(13)
(75)
(13)
(100)
No.
2
0
6
0
8
(%)
(25)
(0)
(75)
(0)
(100)
WEEKS GESTATION AT TIME OF MISCARRIAGE/STILLBIRTH
Age (weeks)
<24
24-27
28-32
33-34
35-36
37+
Unknown
TOTAL
No.
3
0
0
0
0
0
5
8
(%)
(38)
(0)
(0)
(0)
(0)
(0)
(63)
(100)
No.
0
0
0
0
0
0
8
8
(%)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
(100)
GESTATIONAL AGE OF EARLY ONSET CASES
Age (weeks)
<28
28-32
33-34
35-36
37+
Unknown
TOTAL
No.
2
2
0
0
18
0
22
(%)
(9)
(9)
(0)
(0)
(82)
(0)
(100)
No.
6
1
1
2
17
1
28
(%)
(21)
(4)
(4)
(7)
(61)
(4)
(100)
BIRTH WEIGHT OF EARLY ONSET CASES
Weight (grams)
<1000
1000-1999
2000-2999
>3000+
Unknown
TOTAL
No.
2
2
1
17
0
22
(%)
(9)
(9)
(5)
(77)
(0)
(100)
No.
5
2
4
17
0
28
(%)
(18)
(7)
(14)
(61)
(0)
(100)
Cases of Group B Streptococcal Disease
by Date Cultured, Minnesota
January 1, 2001 – December 31, 2002
20
Maternal Case
Maternal Case with
miscarriage/stillbirth
Infant Case - Early Onset
Infant Case - Late Onset
Death
Non-maternal/non-infant Case
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2002
2001
Month of Culture
TABLE 6
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE, JANUARY 1, 2001 - DECEMBER 31, 2002,
TWIN CITIES METRO AREA ONLY IN 2001
STATEWIDE IN 2002
TWIN CITIES METRO
1/1/20011/1/200212/31/2001
12/31/2002
GREATER MN
1/1/200212/31/2002
TOTAL
1/1/200212/31/2002
AGE
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
No.
23
24
34
24
23
56
42
69
44
339
(%)
(7)
(7)
(10)
(7)
(7)
(17)
(12)
(20)
(13)
(100)
No.
11
13
18
15
18
49
75
62
39
300
(%)
(4)
(4)
(6)
(5)
(6)
(16)
(25)
(21)
(13)
(100)
No.
10
10
11
14
7
44
53
84
65
298
(%)
(3)
(3)
(4)
(5)
(2)
(15)
(18)
(28)
(22)
(100)
No.
21
23
29
29
25
93
128
146
104
598
(%)
(4)
(4)
(5)
(5)
(4)
(16)
(21)
(24)
(17)
(100)
No.
180
159
339
(%)
(53)
(47)
(100)
No.
160
140
300
(%)
(53)
(47)
(100)
No.
154
144
298
(%)
(52)
(48)
(100)
No.
314
284
598
(%)
(53)
(47)
(100)
No.
200
32
(%)
(59)
(9)
No.
177
35
(%)
(59)
(12)
No.
178
0
(%)
(60)
(0)
No.
355
35
(%)
(59)
(6)
3
10
94
339
(1)
(3)
(28)
(100)
4
5
79
300
(1)
(2)
(26)
(100)
2
0
118
298
(1)
(0)
(40)
(100)
6
5
197
598
(1)
(1)
(33)
(100)
GENDER
Gender
Male
Female
TOTAL
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
Other/Unknown
TOTAL
TABLE 6 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE, JANUARY 1, 2001 - DECEMBER 31, 2002,
TWIN CITIES METRO AREA ONLY IN 2001
STATEWIDE IN 2002
TWIN CITIES METRO
1/1/20011/1/200212/31/2001
12/31/2002
GREATER MN
1/1/200212/31/2002
TOTAL
1/1/200212/31/2002
OUTCOME
Survived
Yes
No
TOTAL
No.
309
30
339
(%)
(91)
(9)
(100)
No.
268
32
300
(%)
(89)
(11)
(100)
No.
260
38
298
(%)
(87)
(13)
(100)
No.
528
70
598
(%)
(88)
(12)
(100)
No.
306
1
11
0
11
4
1
5
339
(%)
(90)
(<1)
(3)
(0)
(3)
(1)
(<1)
(1)
(100)
No.
270
0
18
1
6
1
3
1
300
(%)
(90)
(0)
(6)
(<1)
(2)
(<1)
(1)
(<1)
(100)
No.
269
1
17
0
3
2
1
5
298
(%)
(90)
(<1)
(6)
(0)
(1)
(1)
(<1)
(2)
(100)
No.
539
1
35
1
9
3
4
6
598
(%)
(90)
(<1)
(6)
(<1)
(2)
(1)
(1)
(1)
(100)
No.
(%)
No.
(%)
No.
(%)
No.
(%)
125
172
17
8
2
3
12
339
(37)
(51)
(5)
(2)
(1)
(1)
(4)
(100)
80
177
21
1
2
1
18
300
(27)
(59)
(7)
(<1)
(1)
(<1)
(6)
(100)
106
156
25
1
0
0
10
298
(36)
(52)
(8)
(<1)
(0)
(0)
(3)
(100)
186
333
46
2
2
1
28
598
(31)
(56)
(8)
(<1)
(<1)
(<1)
(5)
(100)
SITE OF ISOLATE CULTURE
Culture Site
Blood only
Blood and CSF
CSF only
Pericardial Fluid
Pleural
Joint
Peritoneal Fluid
Other
TOTAL
TYPE OF INFECTION
Type
Bacteremia
without focus
Pneumonia
Meningitis
Otitis
Cellulitis
Arthritis
Other/Unknown
TOTAL
TABLE 6 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE, JANUARY 1, 2001 - DECEMBER 31, 2002,
TWIN CITIES METRO AREA ONLY IN 2001
STATEWIDE IN 2002
TWIN CITIES METRO
1/01/20011/01/200212/31/2002
12/31/2001
GREATER MN
1/01/200212/31/2002
TOTAL
1/01/200212/31/2002
PENICILLIN SUSCEPTIBILITY
Susceptibility
Susceptible (MIC < 0.06)
Intermediate
(MIC = 0.12 - 1.0)
Resistant (MIC > 2.0)
Unknown
TOTAL
No.
235
21
(%)
(69)
(6)
No.
230
21
(%)
(77)
(7)
48
35
339
(14)
(10)
(100)
34
15
300
(11)
(5)
(100)
No.
195
17
(%)
(65)
(6)
30 (10)
56 (19)
298 (100)
No.
425
38
(%)
(71)
(6)
64 (11)
71 (12)
598 (100)
PENICILLIN NON-SUSCEPTIBILITY* BY AGE
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
Total
7 / 23
5 / 24
8 / 34
3 / 24
5 / 23
5 / 56
7 / 42
18 / 69
11 / 44
69 / 339
(%)
Total
(30) 5 / 11
(21) 3 / 13
(24) 2 / 18
(13) 3 / 15
(22) 2 / 18
(9) 8 / 49
(17) 11 / 75
(26) 15 / 62
(25) 6 / 39
(20) 55 / 300
(%)
(45)
(23)
(11)
(20)
(11)
(16)
(15)
(24)
(15)
(18)
Total
1 / 10
2 / 10
1 / 11
1 / 14
1/ 7
6 / 44
10 / 53
13 / 84
12 / 65
47 / 298
Total
6 / 21
5 / 23
3 / 29
4 / 29
3 / 25
14 / 93
21 / 128
28 / 146
18 / 104
102 / 598
(%)
(29)
(22)
(10)
(14)
(12)
(15)
(16)
(19)
(17)
(17)
(%)
Total
(16) 33 / 186
(15) 52 / 333
(12) 8 / 46
(27) 9 / 33
(16) 102 / 598
(%)
(18)
(16)
(17)
(27)
(17)
(%)
(10)
(20)
(9)
(7)
(14)
(14)
(19)
(15)
(18)
(16)
PENICILLIN NON-SUSCEPTIBILITY* BY TYPE OF INFECTION
Type
Bacteremia
Pneumonia
Meningitis
Other/Unknown
TOTAL
Total
24 / 125
32 / 172
8 / 17
5 / 25
69 / 339
(%)
Total
(19) 16 / 80
(19) 28 / 177
(47) 5 / 21
(20) 6 / 22
(20) 55 / 300
(%)
Total
(20) 17 / 106
(16) 24 / 156
(24) 3 / 25
(27) 3 / 11
(18) 47 / 298
*Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml.
Cases of S. pneumoniae by Week of Culture, Twin Cities
Metropolitan Area, January 1, 2001 - December 31, 2001
22
20
Penicillin Non-Susceptible*
18
Death
16
Number of Cases
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
2001 - Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Aug
Sep
Oct
Nov
Dec
Cases of S. pneumoniae by Week of Culture, Twin Cities
Metropolitan Area, January 1, 2002 - December 31, 2002
Penicillin Non-Susceptible*
Death
16
Number of Cases
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
2002 - Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Oct
Nov
Dec
Cases of S. pneumoniae by Week of Culture, Minnesota,
January 1, 2002 - December 31, 2002
24
Penicillin Non-Susceptible*
22
Death
20
Number of Cases
18
16
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
2002 - Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Sep
Oct
Nov
Dec