MINNESOTA DEPARTMENT OF HEALTH
EMERGING INFECTIONS PROGRAM
REPORTED CASES OF INVASIVE BACTERIAL DISEASE
JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/200312/31/2003
Rate per
No. 100,000*
1/1/200212/31/2002
Rate per
No. 100,000*
PATHOGEN
Neisseria meningitidis
Serogroup B
Serogroup C
Serogroup Y
Serogroup W135
Serogroup X
Not groupable
Reported but isolate not
available
Haemophilus influenzae
type a
type b
type c
type d
type e
type f
Non-typeable
Reported but isolate not
available
36
0.73
8
17
9
1
1
0
8
16
3
1
0
1
0
0
52
1.06
2
1
1
2
4
11
22
0
5
2
0
4
8
34
9
4
29
0.59
57
1.16
Group A streptococcus
147
2.99
181
3.68
Group B streptococcus
312
6.34
329
6.69
Streptococcus pneumoniae
598
12.16
607
12.34
*Annual rate using populations from the U.S. Bureau of the Census 2000
Note:
Active surveillance for these pathogens began April 1, 1995. Previous reports have
summarized data for 4/1/95-12/31/02. This current report can also be located via
the MDH Web Page at: www.health.state.mn.us
MDH Emerging Infections Program (612) 676-5414
TABLE 2
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
NEISSERIA MENINGITIDIS , JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/200212/31/2002
1/1/200312/31/2003
1/1/200212/31/2002
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No. (%)
8 (22)
28 (78)
36 (100)
OUTCOME
No. (%)
19 (66)
10 (34)
29 (100)
Survived
Yes
No
TOTAL
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60+
TOTAL
No. (%)
31 (86)
5 (14)
36 (100)
No. (%)
5 (14)
6 (17)
2
(6)
5 (14)
3
(8)
1
(3)
3
(8)
1
(3)
10 (28)
36 (100)
No. (%)
2
(7)
2
(7)
2
(7)
9 (31)
5 (17)
3 (10)
6 (21)
0
(0)
0
(0)
29 (100)
No. (%)
17 (47)
19 (53)
36 (100)
No. (%)
15 (52)
14 (48)
29 (100)
Site
Blood
CSF
Other
TOTAL
No. (%)
22 (61)
13 (36)
1
(3)
36 (100)
No.
15
2
No. (%)
15 (52)
9 (31)
5 (17)
29 (100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Septic arthritis
Pericarditis
Otitis
Other
TOTAL
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
> 2 Races
Other Only
Unknown
TOTAL
No. (%)
26 (90)
3 (10)
29 (100)
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200312/31/2003
No. (%)
17 (47)
16 (44)
3
(8)
0
(0)
0
(0)
0
(0)
0
(0)
36 (100)
No. (%)
4 (14)
17 (59)
2
(7)
1
(3)
1
(3)
0
(0)
4 (14)
29 (100)
SEROGROUP
(%)
(42)
(6)
1
(3)
0
(0)
0
(0)
3
(8)
15 (42)
36 (100)
No.
12
3
(%)
(41)
(10)
0
(0)
0
(0)
0
(0)
1
(3)
13 (45)
29 (100)
Serogroup
B
C
Y
W135
X
Not groupable
Unknown
TOTAL
No. (%)
8 (22)
17 (47)
9 (25)
1
(3)
1
(3)
0
(0)
0
(0)
36 (100)
No. (%)
8 (28)
16 (55)
3 (10)
1
(3)
0
(0)
1
(3)
0
(0)
29 (100)
Cases of Neisseria meningitidis Invasive
Disease by Culture Date, Minnesota
January 1, 2002 - December 31, 2003
Serogroup B
Serogroup C
Serogroup Y
Serogroup W135
Number of Cases
12
Serogroup X
10
Not Groupable/Unk
Death
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2002
2003
Month of Culture
TABLE 3
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/200212/31/2002
1/1/200312/31/2003
1/1/200212/31/2002
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
OUTCOME
No.
(%)
24 (46)
28 (54)
52 (100)
No.
(%)
27 (47)
30 (53)
57 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
(%)
8 (15)
0
(0)
1
(2)
3
(6)
4
(8)
2
(4)
0
(0)
11 (21)
4
(8)
19 (37)
52 (100)
No.
(%)
8 (14)
4
(7)
1
(2)
3
(5)
0
(0)
1
(2)
0
(0)
10 (18)
8 (14)
22 (39)
57 (100)
No.
(%)
49 (94)
3
(6)
52 (100)
No. (%)
49 (86)
8 (14)
57 (100)
No.
(%)
31 (60)
21 (40)
52 (100)
No.
23
3
Site
Blood
CSF
Peritoneal
Joint
Pleural fluid
Other
TOTAL
No.
(%)
41 (79)
4
(8)
0
(0)
2
(4)
2
(4)
3
(6)
52 (100)
No. (%)
49 (86)
3
(5)
1
(2)
1
(2)
0
(0)
3
(5)
57 (100)
TYPE OF INFECTION
No.
(%)
29 (51)
28 (49)
57 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
> 2 Races
Other Only
Unknown
TOTAL
Survived
Yes
No
TOTAL
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200312/31/2003
(%)
(44)
(6)
3
(6)
1
(2)
1
(2)
2
(4)
19 (37)
52 (100)
No.
32
5
(%)
(56)
(9)
1
(2)
0
(0)
0
(0)
1
(2)
18 (32)
57 (100)
Type
Bacteremia
Pneumonia
Meningitis
Cellulitis
Peritonitis
Epiglottitis
Chorioamnionitis
Arthritis
Sinusitis
Other
TOTAL
No.
(%)
17 (33)
17 (33)
7 (13)
1
(2)
0
(0)
1
(2)
0
(0)
1
(2)
0
(0)
8 (15)
52 (100)
No. (%)
18 (32)
23 (40)
4
(7)
1
(2)
1
(2)
2
(4)
0
(0)
2
(4)
0
(0)
6 (11)
57 (100)
TABLE 3 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/200312/31/2003
1/1/200212/31/2002
ISOLATE SEROTYPE
Type
a
b
c
d
e
f
Non-typeable
Missing
TOTAL
No.
2
1
1
2
4
11
22
9
52
(%)
(4)
(2)
(2)
(4)
(8)
(21)
(42)
(17)
(100)
No.
0
5
2
0
4
8
34
4
57
(%)
(0)
(9)
(4)
(0)
(7)
(14)
(60)
(7)
(100)
SEROTYPE B (Hib) CASES BY AGE
Age (Years)
<1
1-4
5-9
10-14
15-19
20-39
40-59
60+
TOTAL
No.
1
0
0
0
0
0
0
0
1
(%)
(100)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
No.
2
0
0
0
0
0
2
1
5
(%)
(40)
(0)
(0)
(0)
(0)
(0)
(40)
(20)
(100)
Cases of Haemophilus influenzae Invasive
Disease by Culture Date, Minnesota
January 1, 2002 - December 31, 2003
Type b
Death
Number of Cases
12
10
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2003
2002
Month of Culture
TABLE 4
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/0212/31/2002
RESIDENCE
Residence
No.
(%)
Twin Cities Metro Area
82
(56)
Greater Minnesota
65
(44)
TOTAL
147
(100)
1/1/0312/31/2003
No.
(%)
98 (54)
83 (46)
181 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
2
6
7
10
6
11
19
19
23
44
147
(%)
(1)
(4)
(5)
(7)
(4)
(7)
(13)
(13)
(16)
(30)
(100)
No.
(%)
1
(1)
13
(7)
12
(7)
9
(5)
9
(5)
20 (11)
23 (13)
11
(6)
27 (15)
56 (31)
181 (100)
(%)
(50)
(50)
(100)
No.
(%)
90 (50)
91 (50)
181 (100)
GENDER
Gender
Male
Female
TOTAL
No.
73
74
147
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
Other
Unknown
TOTAL
No.
99
5
(%)
(67)
(3)
No.
129
6
(%)
(71)
(3)
5
1
0
37
147
(3)
(1)
(0)
(25)
100
4
4
4
34
181
(2)
(2)
(2)
(19)
100
1/1/0212/31/2002
1/1/0312/31/2003
SITE OF ISOLATE CULTURE
Site
No.
(%)
No.
(%)
Blood only
92 (63)
101 (56)
CSF only
1
(1)
0
(0)
Blood and other
5
(3)
22 (12)
11
(7)
19 (10)
Joint
Surgical Specimen
7
(5)
0
(0)
Peritoneal
2
(1)
2
(1)
Pleural
5
(3)
6
(3)
Middle ear
1
(1)
0
(0)
Bone
0
(0)
2
(1)
Surgical Aspirate
5
(3)
0
(0)
Muscle
8
(5)
8
(4)
1
(1)
5
(3)
Internal Body Site
Other sterile site
9
(6)
16
(9)
TOTAL
147 (100)
181 (100)
TYPE OF INFECTION
Type
No.
(%)
Bacteremia only
30 (20)
Meningitis
1
(1)
Pneumonia only
10
(7)
Cellulitis only
36 (24)
Necrotizing fasciitis
(NF) only
8
(5)
Peritonitis
1
(1)
Arthritis only
7
(5)
1
(1)
Osteomyelitis
Endometritis
2
(1)
Abscess
9
(6)
Otitis Media
2
(1)
Peurperal Sepsis
1
(1)
STSS
4
(3)
Pneumonia + other
3
(2)
NF + other
5
(3)
Cellulitis + other
10
(7)
Abscess + other
3
(2)
Other + Epiglot (2)
14 (10)
TOTAL
147 (100)
No.
45
0
12
41
(%)
(25)
(0)
(7)
(23)
9
(5)
3
(2)
6
(3)
3
(2)
1
(1)
8
(4)
0
(0)
0
(0)
4
(2)
9
(5)
8
(4)
13
(7)
2
(1)
17
(9)
181 (100)
TABLE 4 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/0212/31/2002
1/1/0312/31/2003
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
123
24
0
147
(%)
(84)
(16)
(0)
(100)
No.
159
22
0
181
(%)
(88)
(12)
(0)
(100)
No.
8
0
0
2
0
1
6
1
0
1
0
0
1
0
0
1
1
22
(%)
(36)
(0)
(0)
(9)
(0)
(5)
(27)
(5)
(0)
(5)
(0)
(0)
(5)
(0)
(0)
(5)
(5)
(100)
TYPE OF INFECTION
RESULTING IN DEATH
Type
Bacteremia
Meningitis
Necrotizing fasciitis
Pneumonia
Abscess
STSS
Cellulitis
Peritonitis + STSS
Peurperal Sepsis
Septic Arthritis
Pneumonia + Cellulitis
NF + Cellulitis
Pneumonia + STSS
NF + STSS
Cellulitis + STSS
Strep Pharyngitis/Inf
Mediastinitis
TOTAL
No.
4
0
3
4
1
2
4
0
1
1
0
2
0
1
1
0
0
24
(%)
(17)
(0)
(13)
(17)
(4)
(8)
(17)
(0)
(4)
(4)
(0)
(8)
(0)
(4)
(4)
(0)
(0)
(100)
Cases of Invasive Group A Streptococcal Disease
by Date of Culture, Minnesota
January 1, 2002 – December 31, 2003
Death
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec
2002
2003
Date of Culture
TABLE 5
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/20031/1/200212/31/2002 12/31/2003
1/1/20021/1/200312/31/2002 12/31/2003
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
(%)
188 (60)
124 (40)
312 (100)
OUTCOME
No. (%)
175 (53)
154 (47)
329 (100)
Survived
Yes
No
Unknown
TOTAL
AGE
Age
<7 days
7-90 days
91 days-11 mos.
1-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
(%)
27
(9)
18
(6)
2
(1)
0
(0)
5
(2)
15
(5)
20
(6)
35 (11)
37 (12)
56 (18)
97 (31)
312 (100)
No.
(%)
166 (53)
146 (47)
312 (100)
No. (%)
20
(6)
16
(5)
2
(1)
0
(0)
2
(1)
6
(2)
20
(6)
39 (12)
46 (14)
50 (15)
128 (39)
329 (100)
Site
Blood only
CSF only
Blood and CSF
Pleural
Joint
Placenta
Amniotic fluid
Surgical Specimen
Internal body site
Peritoneal
Bone
Other
TOTAL
No.
(%)
180 (58)
22
(7)
6
(2)
6
(2)
0
(0)
98 (31)
312 (100)
No. (%)
240 (77)
13
(4)
0
(0)
3
(1)
22
(7)
8
(3)
0
(0)
1
(0)
0
(0)
8
(3)
17
(5)
0
(0)
312 (100)
No. (%)
244 (74)
7
(2)
2
(1)
1
(0)
35 (11)
4
(1)
0
(0)
0
(0)
3
(1)
9
(3)
24
(7)
0
(0)
329 (100)
TYPE OF INFECTION
No. (%)
173 (53)
156 (47)
329 (100)
RACE
Race
White
Black
Amer Indian/Alas Native
Asian/Pacific Islander
More than 1 race
Other/Unknown
TOTAL
No. (%)
297 (90)
27
(8)
5
(2)
329 (100)
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
No. (%)
288 (92)
24
(8)
0
(0)
312 (100)
No. (%)
224 (68)
11
(3)
6
(2)
6
(2)
0
(0)
82 (25)
329 (100)
Type
Bacteremia
Meningitis
Pneumonia
Cellulitis
Arthritis
Osteomyelitis
Abscess
Necrotizing fasciitis
Peritonitis
Septic abortion
or stillbirth
Other
No.
139
9
23
46
20
13
10
3
8
6
(%)
(45)
(3)
(7)
(15)
(6)
(4)
(3)
(1)
(3)
(2)
No.
154
9
21
40
24
25
12
4
8
2
(%)
(47)
(3)
(6)
(12)
(7)
(8)
(4)
(1)
(2)
(1)
35
(11)
30
(9)
TOTAL
312 (100)
329 (100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2002 - DECEMBER 31, 2003
EARLY ONSET CASES*
1/1/200212/31/2002
LATE ONSET CASES*
1/1/200212/31/2002
1/1/200312/31/2003
1/1/200312/31/2003
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
19
8
27
(%)
(70)
(30)
(100)
No.
15
5
20
(%)
(75)
(25)
(100)
No.
11
7
18
(%)
(61)
(39)
(100)
No.
10
6
16
(%)
(63)
(38)
(100)
No.
8
10
18
(%)
(44)
(56)
(100)
No.
7
9
16
(%)
(44)
(56)
(100)
GENDER
Gender
Male
Female
TOTAL
No.
11
16
27
(%)
(41)
(59)
(100)
No.
11
9
20
(%)
(55)
(45)
(100)
RACE
Race
White
Black
American Indian/
Alaskan Native
More than 1 race
Asian/Pacific Islander
Other/Unknown
TOTAL
No.
21
1
(%)
(78)
(4)
No.
12
2
(%)
(60)
(10)
No.
13
5
(%)
(72)
(28)
No.
12
1
(%)
(75)
(6)
2
(7)
(0)
(7)
(4)
(100)
1
0
1
4
20
(5)
(0)
(5)
(20)
(100)
0
0
0
18
(0)
(0)
(0)
(0)
(100)
2
0
0
1
16
(13)
(0)
(0)
(6)
(100)
No.
17
1
0
18
(%)
(94)
(6)
(0)
(100)
No.
16
0
0
16
(%)
(100)
(0)
(0)
(100)
(%)
(72)
(22)
(0)
(6)
(100)
No.
12
4
0
0
16
(%)
(75)
(25)
(0)
(0)
(100)
2
1
27
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
26
1
0
27
(%)
(96)
(4)
(0)
(100)
No.
20
0
0
20
(%)
(100)
(0)
(0)
(100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Other
TOTAL
No.
18
1
4
4
27
(%)
(67)
(4)
(15)
(15)
(100)
No.
16
1
3
0
20
(%)
(80)
(5)
(15)
(0)
(100)
No.
13
4
0
1
18
* Early onset is defined as occurring in the first 6 days, and late onset in the 7th-89th days of life.
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/200212/31/2002
1/1/200312/31/2003
TYPE OF CASE
Type of Case*
Maternal case with miscarriage/
stillbirth
Other maternal case
Infant case - early onset
Infant case - late onset
Not pregnant/postpartum/infant case
TOTAL
No.
(%)
No.
(%)
8
6
27
18
253
312
(3)
(2)
(9)
(6)
(81)
(100)
3
1
20
16
289
329
(1)
(0)
(6)
(5)
(88)
(100)
*A maternal case is defined as invasive GBS infection during pregnancy or postpartum. An early onset infant
case is defined as invasive disease occurring in the first 6 days, and late onset in the 7th - 90th days of life.
TYPE OF INFECTION REPORTED FOR MATERNAL CASES
Type
Bacteremia without another
focus of infection
Septic abortion/ stillbirth
Meningitis
Chorioamnionitis
Abscess
Pyelonenephritis
Unknown
Bleeding on ultrasound
TOTAL
No.
(%)
No.
(%)
1
8
0
1
0
1
2
1
14
(7)
(57)
(0)
(7)
(0)
(7)
(14)
(7)
(100)
1
3
0
0
0
0
0
0
4
(25)
(75)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
(%)
(25)
(0)
(0)
(0)
(75)
(0)
(100)
OUTCOME OF FETUS FOR MATERNAL CASES
Outcome
Survived, no apparent clinical illness
Survived, clinical infection
Live birth, neonatal death-GBS related
Miscarriage/stillbirth-likely
GBS-related
Induced abortion
TOTAL
No.
4
1
0
(%)
(29)
(7)
(0)
No.
1
0
0
8
1
14
(57)
(7)
(100)
3
0
4
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/200212/31/2002
1/1/200312/31/2003
SITE OF ISOLATE CULTURE FOR MISCARRIAGES/STILLBIRTHS
Site
Maternal blood
Amniotic fluid
Placenta only
Autopsy only
TOTAL
No.
2
0
6
0
8
(%)
(25)
(0)
(75)
(0)
(100)
No.
1
0
2
0
3
(%)
(33)
(0)
(67)
(0)
(100)
WEEKS GESTATION AT TIME OF MISCARRIAGE/STILLBIRTH
Age (weeks)
<24
24-27
28-32
33-34
35-36
37+
Unknown
TOTAL
No.
0
0
0
0
0
0
8
8
(%)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
(100)
No.
0
0
0
0
0
0
3
3
(%)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
(100)
GESTATIONAL AGE OF EARLY ONSET CASES
Age (weeks)
<28
28-32
33-34
35-36
37+
Unknown
TOTAL
No.
6
1
1
2
17
1
28
(%)
(21)
(4)
(4)
(7)
(61)
(4)
(100)
No.
1
1
1
0
17
0
20
(%)
(5)
(5)
(5)
(0)
(85)
(0)
(100)
BIRTH WEIGHT OF EARLY ONSET CASES
Weight (grams)
<1000
1000-1999
2000-2999
>3000+
Unknown
TOTAL
No.
5
2
4
17
0
28
(%)
(18)
(7)
(14)
(61)
(0)
(100)
No.
1
1
3
15
0
20
(%)
(5)
(5)
(15)
(75)
(0)
(100)
Cases of Group B Streptococcal Disease
by Date Cultured, Minnesota
January 1, 2002 – December 31, 2003
20
Maternal Case
Maternal Case with
miscarriage/stillbirth
Infant Case - Early Onset
Infant Case - Late Onset
Non-maternal/non-infant Case
Death
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2002
2003
Month of Culture
TABLE 6
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE , JANUARY 1, 2002 - DECEMBER 31, 2003
1/1/2002- 1/1/200312/31/2002 12/31/2003
1/1/20021/1/200312/31/2002 12/31/2003
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
OUTCOME
No. (%)
300 (50)
298 (50)
598 (100)
No. (%)
314 (52)
293 (48)
607 (100)
Survived
Yes
No
TOTAL
No. (%)
528 (88)
70 (12)
598 (100)
No. (%)
535 (88)
72 (12)
607 (100)
SITE OF ISOLATE CULTURE
AGE
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
No. (%)
21
(4)
23
(4)
29
(5)
29
(5)
25
(4)
93 (16)
128 (21)
146 (24)
104 (17)
598 (100)
No. (%)
28
(5)
26
(4)
20
(3)
28
(5)
38
(6)
102 (17)
110 (18)
125 (21)
130 (21)
607 (100)
GENDER
Gender
Male
Female
TOTAL
No. (%)
314 (53)
284 (47)
598 (100)
No. (%)
312 (51)
295 (49)
607 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
2 Races or More
Other Only
Unknown
TOTAL
No.
353
33
(%) No.
(59) 384
(6) 37
(%)
(63)
(6)
6
(1)
9
(1)
5
(1) 10
(2)
2 (<1)
1 (<1)
9
(2) 11
(2)
190 (32) 155 (26)
598 (100) 607 (100)
Culture Site
Blood Only
Blood and CSF
CSF Only
Pericardial Fluid
Pleural
Joint
Peritoneal
Other
TOTAL
No. (%)
539 (90)
1 (<1)
35
(6)
1 (<1)
9
(2)
3
(1)
4
(1)
6
(1)
598 (100)
No. (%)
558 (92)
5
(1)
15
(2)
0
(0)
17
(3)
3 (<1)
4
(1)
5
(1)
607 (100)
TYPE OF INFECTION
Type
Bacteremia
without focus
Pneumonia
Meningitis
Otitis
Cellulitis
Other
TOTAL
No.
(%)
186 (31)
333 (56)
46
(8)
2 (<1)
2 (<1)
29
(5)
598 (100)
No.
(%)
177 (29)
358 (59)
36
(6)
4
(1)
2 (<1)
30
(5)
607 (100)
PENICILLIN SUSCEPTIBILITY
Susceptibility
Susceptible (MIC < 0.06)
Intermediate
No.
425
38
(%)
(81)
(7)
No.
488
32
(%)
(86)
(6)
(MIC = 0.12 - 1.0)
Resistant (MIC > 2.0)
TOTAL
Not Tested
64 (12)
527 (100)
71
(12)
47
(8)
567 (100)
40
(7)
TABLE 6 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE , JANUARY 1, 2002 - DECEMBER 31, 2003
PENICILLIN NON-SUSCEPTIBILITY* BY AGE
1/1/200212/31/2002
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
Non-Susceptible
Total
(%)
6 / 21
(29)
5 / 23
(22)
3 / 29
(10)
4 / 29
(14)
3 / 25
(12)
14 / 93
(15)
21 / 128
(16)
28 / 146
(19)
18 / 104
(17)
102 / 598
(17)
1/1/200312/31/2003
Non-Susceptible
Total
(%)
2 / 28
(7)
3 / 26
(12)
3 / 20
(15)
5 / 28
(18)
3 / 38
(8)
5 / 102
(5)
12 / 110
(11)
24 / 125
(19)
22 / 130
(17)
79 / 607
(13)
PENICILLIN NON-SUSCEPTIBILITY* BY TYPE OF INFECTION
1/1/200212/31/2002
Type
Bacteremia
Pneumonia
Meningitis
Other/Unknown
TOTAL
Non-Susceptible
Total
(%)
33 / 186
(18)
52 / 333
(16)
8 / 46
(17)
9 / 33
(27)
102 / 598
(17)
1/1/20039/30/2003
Non-Susceptible
Total
(%)
20 / 177
(11)
48 / 358
(13)
6 / 36
(17)
5 / 36
(14)
79 / 607
(13)
*Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml.
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1, 2002 - December 31, 2002
24
Penicillin Non-Susceptible*
22
Death
20
Number of Cases
18
16
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
2002 - Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Sep
Oct
Nov
Dec
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1, 2003 - December 31, 2003
30
28
26
Penicillin Non-Susceptible*
24
Death
22
20
18
16
Number of Cases
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
2003 - Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Sep
Oct
Nov
Dec