MINNESOTA DEPARTMENT OF HEALTH
EMERGING INFECTIONS PROGRAM
REPORTED CASES OF INVASIVE BACTERIAL DISEASE
JANUARY 1, 2004 - DEC 31, 2005
1/1/200412/31/2004
Rate per
No. 100,000*
PATHOGEN
Neisseria meningitidis
Serogroup B
Serogroup C
Serogroup Y
Serogroup W135
Serogroup X
Not groupable
Reported but isolate not
available
Haemophilus influenzae
type a
type b
type c
type d
type e
type f
Non-typeable
Reported but isolate not
available
24
1/1/200512/31/2005
Rate per
No. 100,000*
0.47
6
12
4
1
0
1
6
5
5
0
0
0
0
0
55
1.09
2
2
1
0
5
10
29
2
1
0
0
1
13
30
6
6
16
0.32
53
1.05
Group A streptococcus
146
2.89
122
2.41
Group B streptococcus
341
6.74
334
6.60
Streptococcus pneumoniae
540
10.67
596
11.78
*Annual rate using population estimates from the U.S. Bureau of the Census 2003
Note:
Active surveillance for these pathogens began April 1, 1995. Previous reports have
summarized data for 4/1/95-12/31/03. This current report can also be located via
the MDH Web Page at: www.health.state.mn.us
MDH Emerging Infections Program (651) 201-5414
TABLE 2
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
NEISSERIA MENINGITIDIS , JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/200412/31/2004
1/1/200512/31/2005
1/1/200412/31/2004
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No. (%)
17 (71)
7 (29)
24 (100)
OUTCOME
No. (%)
11 (69)
5 (31)
16 (100)
Survived
Yes
No
TOTAL
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60+
TOTAL
No. (%)
21 (88)
3 (13)
24 (100)
No. (%)
3 (13)
3 (13)
0
(0)
5 (21)
3 (13)
3 (13)
0
(0)
3 (13)
4 (17)
24 (100)
No. (%)
2 (13)
4 (25)
1
(6)
1
(6)
2 (13)
2 (13)
1
(6)
0
(0)
3 (19)
16 (100)
No. (%)
15 (63)
9 (38)
24 (100)
No. (%)
5 (31)
11 (69)
16 (100)
Site
Blood
CSF
Other
TOTAL
No. (%)
15 (63)
9 (38)
0
(0)
24 (100)
No.
11
1
No. (%)
11 (69)
5 (31)
0
(0)
16 (100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Septic arthritis
Pericarditis
Otitis
Other
TOTAL
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Other Only
Unknown
TOTAL
No. (%)
15 (94)
1
(6)
16 (100)
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200512/31/2005
No. (%)
10 (42)
12 (50)
2
(8)
0
(0)
0
(0)
0
(0)
0
(0)
24 (100)
No. (%)
10 (63)
6 (38)
0
(0)
0
(0)
0
(0)
0
(0)
0
(0)
16 (100)
SEROGROUP
(%)
(46)
(4)
0
(0)
1
(4)
0
(0)
2
(8)
9 (38)
24 (100)
No.
10
0
(%)
(63)
(0)
0
(0)
0
(0)
0
(0)
0
(0)
6 (38)
16 (100)
Serogroup
B
C
Y
W135
X
Not groupable
Unknown
TOTAL
No. (%)
6 (25)
12 (50)
4 (17)
1
(4)
0
(0)
1
(4)
0
(0)
24 (100)
No. (%)
6 (38)
5 (31)
5 (31)
0
(0)
0
(0)
0
(0)
0
(0)
16 (100)
Cases of Neisseria meningitidis Invasive
Disease by Culture Date, Minnesota
January 1, 2004 – December 31, 2005
Serogroup B
Serogroup C
Serogroup Y
12
Number of Cases
Serogroup W135
10
Not Groupable/Unk
Death
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2004
2005
Month of Culture
TABLE 3
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/200412/31/2004
1/1/200512/31/2005
1/1/200412/31/2004
OUTCOME
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
(%)
23 (42)
32 (58)
55 (100)
No.
(%)
22 (42)
31 (58)
53 (100)
No.
(%)
5
(9)
3
(5)
1
(2)
1
(2)
2
(4)
1
(2)
0
(0)
12 (22)
6 (11)
24 (44)
55 (100)
No.
(%)
6 (11)
0
(0)
2
(4)
1
(2)
3
(6)
3
(6)
6 (11)
5
(9)
10 (19)
17 (32)
53 (100)
No.
(%)
19 (35)
36 (65)
55 (100)
No.
(%)
19 (36)
34 (64)
53 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Other Only
Unknown
TOTAL
No.
(%)
46 (84)
9 (16)
55 (100)
No.
(%)
48 (91)
5
(9)
53 (100)
No.
35
4
Site
Blood
CSF
Peritoneal
Joint
Pleural fluid
Other
TOTAL
No.
(%)
49 (89)
4
(7)
2
(4)
0
(0)
0
(0)
0
(0)
55 (100)
No.
(%)
49 (92)
2
(4)
1
(2)
0
(0)
0
(0)
1
(2)
53 (100)
TYPE OF INFECTION
GENDER
Gender
Male
Female
TOTAL
Survived
Yes
No
TOTAL
SITE OF ISOLATE CULTURE
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
1/1/200512/31/2005
(%)
(64)
(7)
1
(2)
0
(0)
0
(0)
0
(0)
15 (27)
55 (100)
No.
26
2
(%)
(49)
(4)
1
(2)
0
(0)
3
(6)
0
(0)
21 (40)
53 (100)
Type
Bacteremia
Pneumonia
Meningitis
Cellulitis
Peritonitis
Epiglottitis
Chorioamnionitis
Arthritis
Sinusitis
Other
TOTAL
No.
(%)
16 (29)
25 (45)
8 (15)
1
(2)
2
(4)
0
(0)
0
(0)
0
(0)
0
(0)
3
(5)
55 (100)
No.
(%)
20 (38)
20 (38)
2
(4)
1
(2)
1
(2)
1
(2)
0
(0)
3
(6)
2
(4)
3
(6)
53 (100)
TABLE 3 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/200412/31/2004
1/1/200512/31/2005
ISOLATE SEROTYPE
Type
a
b
c
d
e
f
Non-typeable
TOTAL
No.
2
2
1
0
5
10
29
49
(%)
(4)
(4)
(2)
(0)
(10)
(20)
(59)
(100)
No.
2
1
0
0
1
13
30
47
(%)
(4)
(2)
(0)
(0)
(2)
(28)
(64)
(100)
Not Tested
No.
6
(%)*
(11)
No.
6
(%)*
(11)
SEROTYPE B (Hib) CASES BY AGE
Age (Years)
<1
1-4
5-9
10-14
15-19
20-39
40-59
60+
TOTAL
*of total cases
No.
1
0
0
0
0
0
1
0
2
(%)
(50)
(0)
(0)
(0)
(0)
(0)
(50)
(0)
(100)
No.
0
0
0
0
0
1
0
0
1
(%)
(0)
(0)
(0)
(0)
(0)
(100)
(0)
(0)
(100)
Cases of Haemophilus influenzae Invasive
Disease by Culture Date, Minnesota
January 1, 2004 - December 31, 2005
Type b
Death
Number of Cases
12
10
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2005
2004
Month of Culture
TABLE 4
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/0412/31/2004
RESIDENCE
Residence
No.
(%)
Twin Cities Metro Area
84
(58)
Greater Minnesota
62
(42)
TOTAL
146
(100)
1/1/0512/31/2005
No.
(%)
62 (51)
60 (49)
122 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
4
10
7
7
11
13
13
20
17
44
146
(%)
(3)
(7)
(5)
(5)
(8)
(9)
(9)
(14)
(12)
(30)
(100)
No.
(%)
4
(3)
7
(6)
7
(6)
3
(2)
8
(7)
16 (13)
13 (11)
14 (11)
18 (15)
32 (26)
122 (100)
(%)
(51)
(49)
(100)
No.
(%)
64 (52)
58 (48)
122 (100)
GENDER
Gender
Male
Female
TOTAL
No.
74
72
146
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
More than One Race
Unknown
TOTAL
No.
95
9
(%)
(65)
(6)
No.
85
5
(%)
(70)
(4)
4
3
4
31
146
(3)
(2)
(3)
(21)
100
2
1
1
28
122
(2)
(1)
(1)
(23)
100
1/1/0412/31/2004
1/1/0512/31/2005
SITE OF ISOLATE CULTURE
Site
No.
(%)
No.
(%)
Blood only
84 (58)
73 (60)
CSF only
0
(0)
0
(0)
Blood and other
15 (10)
11
(9)
16 (11)
15 (12)
Joint
Peritoneal
3
(2)
0
(0)
Pericardial
0
(0)
0
(0)
Pleural
4
(3)
6
(5)
Middle ear
0
(0)
0
(0)
Bone
1
(1)
4
(3)
Muscle
6
(4)
2
(2)
Internal Body Site
1
(1)
1
(1)
Other sterile site
16 (11)
10
(8)
TOTAL
146 (100)
122 (100)
TYPE OF INFECTION
Type
No.
(%)
Bacteremia only
47 (32)
Meningitis
1
(1)
Pneumonia only
12
(8)
Cellulitis only
23 (16)
Necrotizing fasciitis
(NF) only
10
(7)
Peritonitis
2
(1)
Arthritis only
10
(7)
2
(1)
Osteomyelitis
Endometritis
1
(1)
Abscess
0
(0)
Empyema
0
(0)
Peurperal Sepsis
2
(1)
STSS
2
(1)
Pneumonia + other
2
(1)
NF + other
6
(4)
Cellulitis + other
7
(5)
Abscess + other
0
(0)
Other + Epiglot (1)
19 (13)
TOTAL
146 (100)
No.
36
0
12
33
(%)
(30)
(0)
(10)
(27)
4
(3)
1
(1)
5
(4)
2
(2)
0
(0)
4
(3)
1
(1)
0
(0)
0
(0)
2
(2)
4
(3)
7
(6)
1
(1)
10
(8)
122 (100)
TABLE 4 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/0412/31/2004
1/1/0512/31/2005
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
128
18
0
146
(%)
(88)
(12)
(0)
(100)
No.
113
9
0
122
(%)
(93)
(7)
(0)
(100)
No.
5
0
0
1
0
0
3
0
0
0
0
0
0
0
0
0
0
9
(%)
(56)
(0)
(0)
(11)
(0)
(0)
(33)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
TYPE OF INFECTION
RESULTING IN DEATH
Type
Bacteremia
Meningitis
Necrotizing fasciitis
Pneumonia
Abscess
STSS
Cellulitis
Peritonitis + STSS
Peurperal Sepsis
Septic Arthritis
Pneumonia + Cellulitis
NF + Cellulitis
Pneumonia + STSS
NF + STSS
Cellulitis + STSS
Strep Pharyngitis/Inf
Mediastinitis
TOTAL
No.
8
0
2
2
0
1
2
0
1
0
1
1
0
0
0
0
0
18
(%)
(44)
(0)
(11)
(11)
(0)
(6)
(11)
(0)
(6)
(0)
(6)
(6)
(0)
(0)
(0)
(0)
(0)
(100)
Cases of Invasive Group A Streptococcal Disease
by Date of Culture, Minnesota
January 1, 2004 – December 31, 2005
Death
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec
2004
2005
Date of Culture
TABLE 5
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/20051/1/200412/31/2004 12/31/2005
1/1/20041/1/200512/31/2004 12/31/2005
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
(%)
189 (55)
152 (45)
341 (100)
OUTCOME
No. (%)
190 (57)
144 (43)
334 (100)
AGE
Age
<7 days
7-90 days
91 days-11 mos.
1-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
(%)
26
(8)
18
(5)
1
(0)
0
(0)
4
(1)
21
(6)
23
(7)
37 (11)
51 (15)
42 (12)
118 (35)
341 (100)
No.
(%)
173 (51)
168 (49)
341 (100)
No. (%)
15
(4)
17
(5)
0
(0)
1
(0)
7
(2)
14
(4)
18
(5)
31
(9)
68 (20)
64 (19)
99 (30)
334 (100)
No.
(%)
221 (65)
18
(5)
5
(1)
8
(2)
3
(1)
86 (25)
341 (100)
No. (%)
312 (93)
22
(7)
0
(0)
334 (100)
Site
Blood only
CSF only
Blood and CSF
Pleural
Joint
Placenta
Amniotic fluid
Surgical Specimen
Internal body site
Peritoneal
Bone
Other
TOTAL
No. (%)
246 (72)
10
(3)
0
(0)
3
(1)
27
(8)
9
(3)
1
(0)
0
(0)
5
(1)
12
(4)
26
(8)
2
(1)
341 (100)
No. (%)
249 (75)
9
(3)
0
(0)
2
(1)
35 (10)
5
(1)
3
(1)
0
(0)
0
(0)
4
(1)
27
(8)
0
(0)
334 (100)
TYPE OF INFECTION
No. (%)
180 (54)
154 (46)
334 (100)
RACE
Race
White
Black
Amer Indian/Alas Native
Asian/Pacific Islander
More than 1 race
Other/Unknown
TOTAL
No. (%)
321 (94)
20
(6)
0
(0)
341 (100)
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
Survived
Yes
No
Unknown
TOTAL
No. (%)
211 (63)
21
(6)
2
(1)
5
(1)
4
(1)
91 (27)
334 (100)
Type
Bacteremia
Meningitis
Pneumonia
Cellulitis
Arthritis
Osteomyelitis
Abscess
Necrotizing fasciitis
Peritonitis
Septic abortion
or stillbirth
Other
TOTAL
No.
158
12
30
40
24
26
11
0
8
11
(%)
(46)
(4)
(9)
(12)
(7)
(8)
(3)
(0)
(2)
(3)
21
(6)
341 (100)
No.
142
13
24
56
30
22
11
1
5
9
(%)
(43)
(4)
(7)
(17)
(9)
(7)
(3)
(0)
(1)
(3)
21
(6)
334 (100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2004 - DECEMBER 31, 2005
EARLY ONSET CASES*
1/1/200412/31/2004
LATE ONSET CASES*
1/1/200512/31/2005
1/1/200412/31/2004
1/1/200512/31/2005
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
17
9
26
(%)
(65)
(35)
(100)
No.
11
4
15
(%)
(73)
(27)
(100)
No.
15
3
18
(%)
(83)
(17)
(100)
No.
12
5
17
(%)
(71)
(29)
(100)
No.
10
8
18
(%)
(56)
(44)
(100)
No.
8
9
17
(%)
(47)
(53)
(100)
GENDER
Gender
Male
Female
TOTAL
No.
10
16
26
(%)
(38)
(62)
(100)
No.
11
4
15
(%)
(73)
(27)
(100)
RACE
Race
White
Black
American Indian/
Alaskan Native
More than 1 race
Asian/Pacific Islander
Other/Unknown
TOTAL
No.
13
5
(%)
(50)
(19)
No.
9
2
(%)
(60)
(13)
No.
11
3
(%)
(61)
(17)
No.
9
5
(%)
(53)
(29)
0
1
1
6
26
(0)
(4)
(4)
(23)
(100)
0
2
2
0
15
(0)
(13)
(13)
(0)
(100)
0
2
0
2
18
(0)
(11)
(0)
(11)
(100)
0
0
2
1
17
(0)
(0)
(12)
(6)
(100)
No.
18
0
0
18
(%)
(100)
(0)
(0)
(100)
No.
17
0
0
17
(%)
(100)
(0)
(0)
(100)
(%)
(50)
(39)
(11)
(0)
(100)
No.
8
7
0
2
17
(%)
(47)
(41)
(0)
(12)
(100)
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
20
3
3
26
(%)
(77)
(12)
(12)
(100)
No.
13
2
0
15
(%)
(87)
(13)
(0)
(100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Other
TOTAL
No.
20
2
2
2
26
(%)
(77)
(8)
(8)
(8)
(100)
No.
9
4
1
1
15
(%)
(60)
(27)
(7)
(7)
(100)
No.
9
7
2
0
18
* Early onset is defined as occurring in the first 6 days, and late onset in the 7th-89th days of life.
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/200412/31/2004
1/1/200512/31/2005
TYPE OF CASE
Type of Case*
Maternal case with miscarriage/stillbirth
Other maternal case
Infant case - early onset
Infant case - late onset
Not pregnant/postpartum/infant case
TOTAL
No.
10
3
26
18
284
341
(%)
(3)
(1)
(8)
(5)
(83)
(100)
No.
7
5
15
17
290
334
(%)
(2)
(1)
(4)
(5)
(87)
(100)
*A maternal case is defined as invasive GBS infection during pregnancy or postpartum. An early onset infant case
is defined as invasive disease occurring in the first 6 days, and late onset in the 7th - 89th days of life.
TYPE OF INFECTION REPORTED FOR MATERNAL CASES
Type
Bacteremia without another focus of infection
Septic abortion/ stillbirth
Meningitis
Chorioamnionitis
Abscess
Pyelonenephritis
Unknown
Endometritis
TOTAL
No.
2
8
0
2
0
0
1
0
13
(%)
(15)
(62)
(0)
(15)
(0)
(0)
(8)
(0)
(100)
No.
2
7
0
1
0
0
0
2
12
(%)
(17)
(58)
(0)
(8)
(0)
(0)
(0)
(17)
(100)
No.
4
1
0
7
0
12
(%)
(33)
(8)
(0)
(58)
(0)
(100)
OUTCOME OF FETUS FOR MATERNAL CASES
Outcome
Survived, no apparent clinical illness
Survived, clinical infection
Live birth, neonatal death-GBS related
Miscarriage/stillbirth-likely GBS-related
Induced abortion
TOTAL
No.
2
1
0
10
0
13
(%)
(15)
(8)
(0)
(77)
(0)
(100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/200412/31/2004
1/1/200512/31/2005
SITE OF ISOLATE CULTURE FOR MISCARRIAGES/STILLBIRTHS
Site
Maternal blood
CSF
Amniotic fluid
Placenta only
Autopsy only
TOTAL
No.
0
1
1
8
0
10
(%)
(0)
(10)
(10)
(80)
(0)
(100)
No.
0
0
3
4
0
7
(%)
(0)
(0)
(43)
(57)
(0)
(100)
GESTATIONAL AGE OF EARLY ONSET CASES
Age (weeks)
<28
28-32
33-34
35-36
37+
Unknown
TOTAL
No.
8
0
1
1
16
0
26
(%)
(31)
(0)
(4)
(4)
(62)
(0)
(100)
No.
2
2
0
1
10
0
15
(%)
(13)
(13)
(0)
(7)
(67)
(0)
(100)
BIRTH WEIGHT OF EARLY ONSET CASES
Weight (grams)
<1000
1000-1999
2000-2999
>3000+
Unknown
TOTAL
No.
8
0
5
13
0
26
(%)
(31)
(0)
(19)
(50)
(0)
(100)
No.
2
2
2
9
0
15
(%)
(13)
(13)
(13)
(60)
(0)
(100)
Cases of Group B Streptococcal Disease
by Date Cultured, Minnesota
January 1, 2004 – December 31, 2005
Maternal Case
Maternal Case with
miscarriage/stillbirth
Infant Case - Early Onset
Infant Case - Late Onset
Non-maternal/non-infant Case
Death
20
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2004
2005
Month of Culture
TABLE 6
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE , JANUARY 1, 2004 - DECEMBER 31, 2005
1/1/2004- 1/1/200512/31/2004 12/31/2005
1/1/20041/1/200512/31/2004 12/31/2005
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
OUTCOME
No. (%)
286 (53)
254 (47)
540 (100)
No. (%)
313 (53)
283 (47)
596 (100)
Survived
Yes
No
TOTAL
No. (%)
491 (91)
49
(9)
540 (100)
No. (%)
552 (93)
44
(7)
596 (100)
SITE OF ISOLATE CULTURE
AGE
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
No. (%)
33
(6)
21
(4)
27
(5)
22
(4)
33
(6)
60 (11)
114 (21)
128 (24)
102 (19)
540 (100)
No. (%)
28
(5)
24
(4)
29
(5)
25
(4)
36
(6)
76 (13)
134 (22)
111 (19)
133 (22)
596 (100)
GENDER
Gender
Male
Female
TOTAL
No. (%)
279 (52)
261 (48)
540 (100)
No. (%)
313 (53)
283 (47)
596 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Unknown
TOTAL
* of total cases
No.
337
28
(%) No.
(62) 350
(5) 46
(%)
(59)
(8)
12
(2) 11 (<1)
6
(1)
5 (<1)
0 (<1)
2 (<1)
157 (29) 182 (31)
540 (100) 596 (100)
Culture Site
Blood Only
Blood and CSF
CSF Only
Pericardial Fluid
Pleural
Joint
Peritoneal
Other
TOTAL
No. (%)
499 (92)
1 (<1)
21
(4)
0
(0)
8
(1)
3
(1)
6
(1)
2 (<1)
540 (100)
No. (%)
553 (93)
1 (<1)
19
(3)
1 (<1)
9
(2)
6
(1)
2 (<1)
5 (<1)
596 (100)
TYPE OF INFECTION
Type
Bacteremia
without focus
Pneumonia
Meningitis
Otitis
Cellulitis
Other
TOTAL
No.
(%)
187 (35)
286 (53)
33
(6)
10
(2)
5 (<1)
19
(4)
540 (100)
No.
(%)
210 (35)
319 (54)
30
(5)
5 (<1)
7
(1)
25
(4)
596 (100)
PENICILLIN SUSCEPTIBILITY
Susceptibility
Susceptible (MIC < 0.06)
Intermediate
No.
393
45
(%)
(82)
(9)
No.
411
75
(%)
(77)
(14)
(MIC = 0.12 - 1.0)
Resistant (MIC > 2.0)
TOTAL
40
(8)
478 (100)
46
(9)
532 (100)
Not Tested
No. (%)*
62 (11)
No. (%)*
64 (11)
TABLE 6 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE WITH SUSCEPTIBILITY TESTING COMPLETED,
JANUARY 1, 2004 - DECEMBER 31, 2005
PENICILLIN NON-SUSCEPTIBILITY* BY AGE
1/1/200412/31/2004
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
Non-Susceptible
Total
(%)
12 / 29
(41)
3 / 21
(14)
4 / 24
(17)
5 / 18
(28)
6 / 32
(19)
7 / 53
(13)
10 / 102
(10)
21 / 112
(19)
17 / 87
(20)
85 / 478
(18)
1/1/200512/31/2005
Non-Susceptible
Total
(%)
4 / 26
(15)
5 / 24
(21)
9 / 29
(31)
4 / 22
(18)
6 / 32
(19)
9 / 71
(13)
28 / 123
(23)
25 / 90
(28)
31 / 115
(27)
121 / 532
(23)
PENICILLIN NON-SUSCEPTIBILITY* BY TYPE OF INFECTION
1/1/200412/31/2004
Type
Bacteremia
Pneumonia
Meningitis
Other/Unknown
TOTAL
Non-Susceptible
Total
(%)
33 / 165
(20)
39 / 253
(15)
(19)
6 / 31
7 / 29
(24)
85 / 478
(18)
1/1/20056/30/2005
Non-Susceptible
Total
(%)
37 / 184
(20)
71 / 286
(25)
7 / 29
(24)
6 / 33
(18)
121 / 532
(23)
*Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml.
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1, 2004 - December 31, 2004
28
26
Penicillin Non-Susceptible*
24
Death
22
20
18
16
Number of Cases
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
2004 - Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Sep
Oct
Nov
Dec
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1, 2005 – December 31, 2005
28
26
Penicillin Non-Susceptible*
24
Death
22
20
18
16
Number of Cases
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
2005 - Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Sep
Oct
Nov
Dec