MINNESOTA DEPARTMENT OF HEALTH
EMERGING INFECTIONS PROGRAM
REPORTED CASES OF INVASIVE BACTERIAL DISEASE
JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
Rate per
No. 100,000*
PATHOGEN
Neisseria meningitidis
Serogroup B
Serogroup C
Serogroup Y
Serogroup W135
Serogroup X
Not groupable
Reported but isolate not
available
Haemophilus influenzae
type a
type b
type c
type d
type e
type f
Non-typeable
Reported but isolate not
available
15
1/1/200712/31/2007
Rate per
No. 100,000*
0.29
5
4
6
0
0
0
6
9
6
0
0
1
0
0
98
1.90
3
4
2
0
7
23
47
4
1
1
2
4
8
53
12
9
22
0.43
82
1.59
Group A streptococcus
171
3.31
173
3.35
Group B streptococcus
361
6.99
331
6.41
Streptococcus pneumoniae
635
12.29
664
12.85
*Annual rate using population estimates from the U.S. Bureau of the Census 2006
Note:
Active surveillance for these pathogens began April 1, 1995. Previous reports have
summarized data for 4/1/95-12/31/05. This current report can also be located via
the MDH Web Page at: www.health.state.mn.us
MDH Emerging Infections Program (651) 201-5414
TABLE 2
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
NEISSERIA MENINGITIDIS , JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
1/1/200712/31/2007
1/1/200612/31/2006
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No. (%)
6 (40)
9 (60)
15 (100)
OUTCOME
No. (%)
11 (50)
11 (50)
22 (100)
Survived
Yes
No
TOTAL
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60+
TOTAL
No. (%)
12 (80)
3 (20)
15 (100)
No. (%)
1
(7)
1
(7)
0
(0)
4 (27)
2 (13)
1
(7)
1
(7)
2 (13)
3 (20)
15 (100)
No. (%)
0
(0)
5 (23)
1
(5)
5 (23)
6 (27)
2
(9)
1
(5)
0
(0)
2
(9)
22 (100)
No. (%)
7 (47)
8 (53)
15 (100)
No. (%)
10 (45)
12 (55)
22 (100)
Site
Blood
CSF
Other
TOTAL
No. (%)
13 (87)
2 (13)
0
(0)
15 (100)
No.
12
1
No. (%)
11 (50)
11 (50)
0
(0)
22 (100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Septic arthritis
Pericarditis
Otitis
Other
TOTAL
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Other Only
Unknown
TOTAL
No. (%)
21 (95)
1
(5)
22 (100)
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200712/31/2007
No. (%)
7 (47)
7 (47)
1
(7)
0
(0)
0
(0)
0
(0)
0
(0)
15 (100)
No. (%)
6 (27)
16 (73)
0
(0)
0
(0)
0
(0)
0
(0)
0
(0)
22 (100)
SEROGROUP
(%)
(80)
(7)
0
(0)
0
(0)
0
(0)
0
(0)
2 (13)
15 (100)
No.
11
2
(%)
(50)
(9)
0
(0)
0
(0)
0
(0)
0
(0)
9 (41)
22 (100)
Serogroup
B
C
Y
W135
X
Not groupable
Unknown
TOTAL
No. (%)
5 (33)
4 (27)
6 (40)
0
(0)
0
(0)
0
(0)
0
(0)
15 (100)
No. (%)
6 (27)
9 (41)
6 (27)
0
(0)
0
(0)
1
(5)
0
(0)
22 (100)
Cases of Neisseria meningitidis Invasive
Disease by Culture Date, Minnesota
January 1, 2006 – December 31, 2007
Serogroup B
Serogroup C
Serogroup Y
12
Number of Cases
Serogroup W135
10
Not Groupable/Unk
Death
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2006
2007
Month of Culture
TABLE 3
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
1/1/200712/312007
1/1/200612/31/2006
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
OUTCOME
No.
(%)
56 (57)
42 (43)
98 (100)
No.
(%)
41 (50)
41 (50)
82 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
(%)
11 (11)
5
(5)
2
(2)
3
(3)
5
(5)
4
(4)
7
(7)
15 (15)
13 (13)
33 (34)
98 (100)
No.
(%)
6
(7)
6
(7)
0
(0)
1
(1)
1
(1)
2
(2)
4
(5)
11 (13)
14 (17)
37 (45)
82 (100)
No.
(%)
86 (88)
12 (12)
98 (100)
No.
(%)
73 (89)
9 (11)
82 (100)
No.
(%)
40 (41)
58 (59)
98 (100)
No.
48
6
Site
Blood
CSF
Peritoneal
Joint
Pleural fluid
Other
TOTAL
No.
(%)
80 (82)
10 (10)
2
(2)
4
(4)
2
(2)
0
(0)
98 (100)
No.
(%)
75 (91)
5
(6)
0
(0)
0
(0)
1
(1)
1
(1)
82 (100)
TYPE OF INFECTION
No.
(%)
43 (52)
39 (48)
82 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Other Only
Unknown
TOTAL
Survived
Yes
No
TOTAL
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200712/31/2007
(%)
(49)
(6)
1
(1)
2
(2)
3
(3)
1
(1)
37 (38)
98 (100)
No.
53
3
(%)
(65)
(4)
1
(1)
0
(0)
1
(1)
0
(0)
24 (29)
82 (100)
Type
Bacteremia
Pneumonia
Meningitis
Cellulitis
Peritonitis
Epiglottitis
Chorioamnionitis
Arthritis
Sinusitis
Other
TOTAL
No.
(%)
39 (40)
38 (39)
10 (10)
1
(1)
2
(2)
0
(0)
0
(0)
4
(4)
0
(0)
4
(4)
98 (100)
No.
(%)
36 (44)
37 (45)
5
(6)
0
(0)
0
(0)
1
(1)
0
(0)
0
(0)
0
(0)
3
(4)
82 (100)
TABLE 3 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
1/1/200712/31/2007
ISOLATE SEROTYPE
Type
a
b
c
d
e
f
Non-typeable
TOTAL
No.
3
4
2
0
7
23
47
86
(%)
(3)
(5)
(2)
(0)
(8)
(27)
(55)
(100)
No.
4
1
1
2
4
8
53
73
(%)
(5)
(1)
(1)
(3)
(5)
(11)
(73)
(100)
Not Tested
No.
21
(%)*
(38)
No.
9
(%)*
(17)
SEROTYPE B (Hib) CASES BY AGE
Age (Years)
<1
1-4
5-9
10-14
15-19
20-39
40-59
60+
TOTAL
*of total cases
No.
1
1
0
0
0
0
0
2
4
(%)
(25)
(25)
(0)
(0)
(0)
(0)
(0)
(50)
(100)
No.
0
1
0
0
0
0
0
0
1
(%)
(0)
(100)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
Cases of Haemophilus influenzae Invasive
Disease by Culture Date, Minnesota
January 1, 2006 – December 31, 2007
Type b
Death
Number of Cases
12
10
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2007
2006
Month of Culture
TABLE 4
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
RESIDENCE
Residence
No.
(%)
Twin Cities Metro Area
80
(47)
Greater Minnesota
91
(53)
171
(100)
TOTAL
1/1/2000712/31/2007
No. (%)
94 (54)
79 (46)
173 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
2
9
12
8
10
13
23
22
21
51
171
(%)
(1)
(5)
(7)
(5)
(6)
(8)
(13)
(13)
(12)
(30)
(100)
No. (%)
7
(4)
8
(5)
10
(6)
9
(5)
11
(6)
12
(7)
26 (15)
27 (16)
24 (14)
39 (23)
173 (100)
(%)
(48)
(52)
(100)
No. (%)
84 (49)
89 (51)
173 (100)
GENDER
Gender
Male
Female
TOTAL
No.
82
89
171
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
More than One Race
Unknown
TOTAL
No.
116
4
(%)
(68)
(2)
No.
113
7
(%)
(65)
(4)
3
3
0
45
171
(2)
(2)
(0)
(26)
100
4
3
0
46
173
(2)
(2)
(0)
(27)
100
1/1/200612/31/2006
1/1/200712/31/2007
SITE OF ISOLATE CULTURE
Site
No. (%)
No. (%)
Blood only
102 (60) 105 (61)
CSF only
1
(1)
2
(1)
Blood and other
32 (19)
25 (14)
Joint
14
(8)
11
(6)
Peritoneal
1
(1)
2
(1)
Pericardial
0
(0)
0
(0)
Pleural
10
(6)
6
(3)
Middle ear
0
(0)
0
(0)
Bone
2
(1)
4
(2)
Muscle
1
(1)
2
(1)
Internal Body Site
3
(2)
4
(2)
Other sterile site
5
(3)
12
(7)
TOTAL
171 (100) 173 (100)
TYPE OF INFECTION
Type
No. (%)
Bacteremia only
59 (35)
Meningitis
4
(2)
Pneumonia only
22 (13)
Cellulitis only
28 (16)
Necrotizing fasciitis
(NF) only
5
(3)
Otitis
0
(0)
Arthritis only
5
(3)
Osteomyelitis
2
(1)
Endometritis
1
(1)
Abscess
3
(2)
Empyema/Peritonitis
1
(1)
Endocarditis
1
(1)
STSS
0
(0)
Pneumonia + other
4
(2)
NF + other
6
(4)
Cellulitis + other
10
(6)
Abscess + other
1
(1)
Other/Unknown (2)
19 (11)
TOTAL
171 (100)
No.
59
1
16
27
(%)
(34)
(1)
(9)
(16)
10
(6)
1
(1)
10
(6)
5
(3)
2
(1)
5
(3)
2
(1)
0
(0)
0
(0)
6
(3)
4
(2)
11
(6)
2
(1)
12
(7)
173 (100)
TABLE 4 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
1/1/200712/31/2007
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
154
17
0
171
(%)
(90)
(10)
(0)
(100)
No.
157
16
0
173
(%)
(91)
(9)
(0)
(100)
No.
8
0
2
2
0
1
1
0
2
16
(%)
(50)
(0)
(13)
(13)
(0)
(6)
(6)
(0)
(13)
(100)
TYPE OF INFECTION
RESULTING IN DEATH
Type
Bacteremia
Meningitis
Necrotizing fasciitis
Pneumonia
Cellulitis
Peritonitis
Pneumonia/Cellulitis
Petechia/Vasculitis
Unknown
TOTAL
No.
6
2
1
5
2
0
0
1
0
17
(%)
(35)
(12)
(6)
(29)
(12)
(0)
(0)
(6)
(0)
(100)
Cases of Invasive Group A Streptococcal Disease
by Date of Culture, Minnesota
January 1, 2006 – December 31, 2007
Death
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec
2006
2007
Date of Culture
TABLE 5
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
1/1/200712/31/2007
1/1/200612/31/2006
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
(%)
206 (57)
155 (43)
361 (100)
OUTCOME
No. (%)
170 (51)
162 (49)
332 (100)
AGE
Age
<7 days
7-90 days
91 days-11 mos.
1-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
(%)
25
(7)
21
(6)
3
(1)
2
(1)
2
(1)
15
(4)
19
(5)
40 (11)
47 (13)
59 (16)
128 (35)
361 (100)
No.
(%)
188 (52)
173 (48)
361 (100)
No. (%)
23
(7)
13
(4)
1
(0)
2
(1)
4
(1)
14
(4)
24
(7)
30
(9)
55 (17)
59 (18)
107 (32)
332 (100)
No.
(%)
193 (53)
25
(7)
5
(1)
9
(2)
2
(1)
127 (35)
361 (100)
No. (%)
343 (95)
18
(5)
0
(0)
361 (100)
No. (%)
319 (96)
12
(4)
1
(0)
332 (100)
Site
Blood only
CSF only
Blood and CSF
Pleural
Joint
Placenta
Amniotic fluid
Surgical Specimen
Internal body site
Peritoneal
Bone
Other
TOTAL
No. (%)
283 (78)
5
(1)
0
(0)
2
(1)
31
(9)
9
(2)
0
(0)
0
(0)
1
(0)
9
(2)
20
(6)
1
(0)
361 (100)
No. (%)
261 (79)
3
(1)
0
(0)
0
(0)
25
(8)
4
(1)
1
(0)
0
(0)
3
(1)
4
(1)
27
(8)
4
(1)
332 (100)
TYPE OF INFECTION
No. (%)
187 (56)
145 (44)
332 (100)
RACE
Race
White
Black
Amer Indian/Alas Native
Asian/Pacific Islander
More than 1 race
Other/Unknown
TOTAL
Survived
Yes
No
Unknown
TOTAL
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200712/31/2007
No. (%)
209 (63)
15
(5)
5
(2)
5
(2)
2
(1)
96 (29)
332 (100)
Type
Bacteremia
Meningitis
Pneumonia
Cellulitis
Arthritis
Osteomyelitis
Abscess
Necrotizing fasciitis
Peritonitis
Septic abortion
or stillbirth
Other
TOTAL
No.
196
7
25
53
19
21
11
1
10
7
(%)
(54)
(2)
(7)
(15)
(5)
(6)
(3)
(0)
(3)
(2)
11
(3)
361 (100)
No.
156
5
27
52
21
28
12
1
2
2
(%)
(47)
(2)
(8)
(16)
(6)
(8)
(4)
(0)
(1)
(1)
26
(8)
332 (100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2006 - DECEMBER 31, 2007
EARLY ONSET CASES*
1/1/200612/31/2006
LATE ONSET CASES*
1/1/200612/31/2006
1/1/200712/31/2007
1/1/20076/30/2007
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
17
8
25
(%)
(68)
(32)
(100)
No.
14
9
23
(%)
(61)
(39)
(100)
No.
10
11
21
(%)
(48)
(52)
(100)
No.
8
5
13
(%)
(62)
(38)
(100)
No.
10
11
21
(%)
(48)
(52)
(100)
No.
5
8
13
(%)
(38)
(62)
(100)
GENDER
Gender
Male
Female
TOTAL
No.
13
12
25
(%)
(52)
(48)
(100)
No.
14
9
23
(%)
(61)
(39)
(100)
RACE
Race
White
Black
American Indian/
Alaskan Native
More than 1 race
Asian/Pacific Islander
Other/Unknown
TOTAL
No.
13
5
(%)
(52)
(20)
No.
11
3
(%)
(48)
(13)
No.
9
5
(%)
(43)
(24)
No.
3
5
(%)
(23)
(38)
1
2
1
3
25
(4)
(8)
(4)
(12)
(100)
0
1
1
7
23
(0)
(4)
(4)
(30)
(100)
1
0
0
6
21
(5)
(0)
(0)
(29)
(100)
0
0
0
5
13
(0)
(0)
(0)
(38)
(100)
No.
20
1
0
21
(%)
(95)
(5)
(0)
(100)
No.
13
0
0
13
(%)
(100)
(0)
(0)
(100)
(%)
(81)
(10)
(0)
(10)
(100)
No.
10
2
0
1
13
(%)
(77)
(15)
(0)
(8)
(100)
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
24
1
0
25
(%)
(96)
(4)
(0)
(100)
No.
21
2
0
23
(%)
(91)
(9)
(0)
(100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Other
TOTAL
No.
22
1
1
1
25
(%)
(88)
(4)
(4)
(4)
(100)
No.
19
1
1
2
23
(%)
(83)
(4)
(4)
(9)
(100)
No.
17
2
0
2
21
* Early onset is defined as occurring in the first 6 days, and late onset in the 7th-89th days of life.
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
1/1/20076/30/2007
TYPE OF CASE
Type of Case*
Maternal case with miscarriage/stillbirth
Other maternal case
Infant case - early onset
Infant case - late onset
Not pregnant/postpartum/infant case
TOTAL
No.
10
3
25
21
302
361
(%)
(3)
(1)
(7)
(6)
(84)
(100)
No.
5
5
23
13
286
332
(%)
(2)
(2)
(7)
(4)
(86)
(100)
*A maternal case is defined as invasive GBS infection during pregnancy or postpartum. An early onset infant case
is defined as invasive disease occurring in the first 6 days, and late onset in the 7th - 89th days of life.
TYPE OF INFECTION REPORTED FOR MATERNAL CASES
Type
Bacteremia without another focus of infection
Septic abortion/ stillbirth
Meningitis
Chorioamnionitis
Abscess
Pyelonenephritis
Peritonitis
Cellulitis
Arthritis
Endometritis
Unknown
TOTAL
No.
3
7
0
0
0
1
1
0
0
0
1
13
(%)
(23)
(54)
(0)
(0)
(0)
(8)
(8)
(0)
(0)
(0)
(8)
(100)
No.
2
2
0
2
0
0
0
1
1
1
1
10
(%)
(20)
(20)
(0)
(20)
(0)
(0)
(0)
(10)
(10)
(10)
(10)
(100)
No.
4
0
0
5
1
10
(%)
(40)
(0)
(0)
(50)
(10)
(100)
OUTCOME OF FETUS FOR MATERNAL CASES
Outcome
Survived, no apparent clinical illness
Survived, clinical infection
Live birth, neonatal death-GBS related
Miscarriage/stillbirth-likely GBS-related
Induced abortion
TOTAL
No.
2
0
0
10
1
13
(%)
(15)
(0)
(0)
(77)
(8)
(100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2006 - DECEMBER 31, 2007
1/1/200612/31/2006
1/1/200712/31/2007
SITE OF ISOLATE CULTURE FOR MISCARRIAGES/STILLBIRTHS
Site
Maternal blood
CSF
Amniotic fluid
Placenta only
Peritoneal
Autopsy only
TOTAL
No.
0
0
0
9
1
0
10
(%)
(0)
(0)
(0)
(90)
(10)
(0)
(100)
No.
0
0
1
4
0
0
5
(%)
(0)
(0)
(20)
(80)
(0)
(0)
(100)
GESTATIONAL AGE OF EARLY ONSET CASES
Age (weeks)
<28
28-32
33-34
35-36
37+
Unknown
TOTAL
No.
4
1
0
1
19
0
25
(%)
(16)
(4)
(0)
(4)
(76)
(0)
(100)
No.
4
2
1
3
13
0
23
(%)
(17)
(9)
(4)
(13)
(57)
(0)
(100)
BIRTH WEIGHT OF EARLY ONSET CASES
Weight (grams)
<1000
1000-1999
2000-2999
>3000+
Unknown
TOTAL
No.
0
0
4
20
1
25
(%)
(0)
(0)
(16)
(80)
(4)
(100)
No.
0
0
4
16
3
23
(%)
(0)
(0)
(17)
(70)
(13)
(100)
Cases of Group B Streptococcal Disease by Date Cultured, Minnesota
January 1, 2006 – December 31, 2007
Died
Survived
24
22
20
Number of Cases
18
16
14
12
10
8
6
4
2
0
J
F
M
A
M
J
J
A
S
O
N
D
J
F
M
A
M
J
J
2007
2006
Month of Culture
A
S
O
N
D
TABLE 6
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE , JANUARY 1, 2007 - JUNE 30, 2007
1/1/2005- 1/1/200712/31/2005 6/30/2007
1/1/200512/31/2005
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
OUTCOME
No. (%)
313 (53)
283 (47)
596 (100)
No. (%)
175 (48)
186 (52)
361 (100)
AGE
Survived
Yes
No
TOTAL
No. (%)
26
(7)
13
(4)
13
(4)
18
(5)
12
(3)
57
(16)
80
(22)
67
(19)
75
(21)
361 (100)
Culture Site
Blood Only
Blood and CSF
CSF Only
Pericardial Fluid
Pleural
Joint
Peritoneal
Other
TOTAL
GENDER
No. (%)
189 (52)
172 (48)
361 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Unknown
TOTAL
* of total cases
No.
350
46
(%)
(93)
(7)
(7)
No. (%)
317 (90)
37 (10)
354 (100)
No. (%)
553 (93)
1 (<1)
19
(3)
1 (<1)
9
(2)
6
(1)
2 (<1)
5 (<1)
596 (100)
No. (%)
340 (94)
0
(0)
12
(3)
0 (<1)
5
(1)
1
(0)
0 (<1)
3 (<1)
361 (100)
TYPE OF INFECTION
No. (%)
313 (53)
283 (47)
596 (100)
Gender
Male
Female
TOTAL
No.
552
44
596
SITE OF ISOLATE CULTURE
No. (%)
28
(5)
24
(4)
29
(5)
25
(4)
36
(6)
76 (13)
134 (22)
111 (19)
133 (22)
596 (100)
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
1/1/20076/30/2007
(%) No.
(59) 195
(8) 21
(%)
(54)
(6)
Type
Bacteremia
without focus
Pneumonia
Meningitis
Otitis
Cellulitis
Other
TOTAL
No.
(%)
210 (35)
319 (54)
30
(5)
5 (<1)
7
(1)
25
(4)
596 (100)
No.
(%)
110 (30)
205 (57)
19
(5)
8
(2)
1
(0)
18
(5)
361 (100)
PENICILLIN SUSCEPTIBILITY
11 (<1) 8
(2)
5 (<1) 7
(2)
2 (<1) 5
(<1)
182 (31) 125 (35)
596 (100) 361 (100)
Susceptibility
Susceptible (MIC < 0.06)
Intermediate
No.
411
75
(%)
(77)
(14)
No.
108
22
(%)
(75)
(15)
(MIC = 0.12 - 1.0)
Resistant (MIC > 2.0)
TOTAL
46
(9)
532 (100)
14 (10)
144 (100)
Not Tested
No. (%)*
64 (11)
No. (%)*
217 (61)
TABLE 6 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE WITH SUSCEPTIBILITY TESTING COMPLETED,
JANUARY 1, 2007 - JUNE 30, 2007
PENICILLIN NON-SUSCEPTIBILITY* BY AGE
1/1/200512/31/2005
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
Non-Susceptible
Total
(%)
4 / 26
(15)
5 / 24
(21)
9 / 29
(31)
4 / 22
(18)
6 / 32
(19)
9 / 71
(13)
28 / 123
(23)
25 / 90
(28)
31 / 115
(27)
121 / 532
(23)
1/1/20076/30/2007
Non-Susceptible
Total
(%)
1/ 6
(17)
3/ 6
(50)
2/ 7
(29)
1/ 6
(17)
1/ 4
(25)
5 / 29
(17)
3 / 30
(10)
11 / 29
(38)
9 / 27
(33)
36 / 144 (25)
PENICILLIN NON-SUSCEPTIBILITY* BY TYPE OF INFECTION
1/1/200512/31/2005
Type
Bacteremia
Pneumonia
Meningitis
Other/Unknown
TOTAL
Non-Susceptible
Total
(%)
37 / 184
(20)
71 / 286
(25)
(24)
7 / 29
6 / 33
(18)
121 / 532
(23)
1/1/20076/30/2007
Non-Susceptible
Total
(%)
11 / 110
(10)
21 / 204
(10)
2 / 19
(11)
2 / 28
(7)
36 / 361
(10)
*Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml.
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1 - December 31, 2006
28
Penicillin Non-Susceptible*
26
Death
24
22
Number of Cases
20
18
16
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
2006 Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Sep
Oct
Nov
Dec
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1 - December 31, 2007
30
28
Total cases = 664
Total cases with isolates submitted to MDH = 615
26
Number of Cases
24
22
Penicillin Non-Susceptible*
20
Death
18
16
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
2006 Week of Culture
* Penicillin non-susceptible includes isolates with a MIC > 0.12 µg/ml
Sep
Oct
Nov
Dec