MINNESOTA DEPARTMENT OF HEALTH
EMERGING INFECTIONS PROGRAM
REPORTED CASES OF INVASIVE BACTERIAL DISEASE
JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
Rate per
No. 100,000*
PATHOGEN
Neisseria meningitidis
Serogroup B
Serogroup C
Serogroup Y
Serogroup W135
Serogroup X
Serogropu Z
Not groupable
Reported but isolate not
available
Haemophilus influenzae
type a
type b
type c
type d
type e
type f
Non-typeable
Reported but isolate not
available
22
1/1/200812/31/2008
Rate per
No. 100,000*
0.43
6
9
6
0
0
0
1
13
14
2
1
0
1
0
0
0
82
1.59
4
1
1
2
4
8
53
2
5
0
1
4
12
42
9
6
30
0.58
72
1.39
Group A streptococcus
173
3.35
185
3.58
Group B streptococcus
332
6.43
418
8.09
Streptococcus pneumoniae
664
12.85
712
13.78
*Annual rate using population estimates from the U.S. Bureau of the Census 2006
Note:
Active surveillance for these pathogens began April 1, 1995. Previous reports have
summarized data for 4/1/95-12/31/05. This current report can also be located via
the MDH Web Page at: www.health.state.mn.us
MDH Emerging Infections Program (651) 201-5414
TABLE 2
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
NEISSERIA MENINGITIDIS , JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
1/1/200812/31/2008
1/1/200712/31/2007
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No. (%)
11 (50)
11 (50)
22 (100)
OUTCOME
No. (%)
16 (53)
14 (47)
30 (100)
Survived
Yes
No
TOTAL
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60+
TOTAL
No. (%)
21 (95)
1
(5)
22 (100)
No. (%)
0
(0)
5 (23)
1
(5)
5 (23)
6 (27)
2
(9)
1
(5)
0
(0)
2
(9)
22 (100)
No. (%)
5 (17)
2
(7)
2
(7)
4 (13)
4 (13)
3 (10)
1
(3)
4 (13)
5 (17)
30 (100)
No. (%)
10 (45)
12 (55)
22 (100)
No. (%)
17 (57)
13 (43)
30 (100)
Site
Blood
CSF
Joint
TOTAL
No. (%)
11 (50)
11 (50)
0
(0)
22 (100)
No.
11
2
No. (%)
14 (47)
14 (47)
2
(7)
30 (100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Septic arthritis
Pericarditis
Otitis
Cellulitis
TOTAL
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Other Only
Unknown
TOTAL
No. (%)
27 (90)
3 (10)
30 (100)
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200812/31/2008
No. (%)
6 (27)
16 (73)
0
(0)
0
(0)
0
(0)
0
(0)
0
(0)
22 (100)
No. (%)
6 (20)
18 (60)
3 (10)
2
(7)
0
(0)
0
(0)
1
(3)
30 (100)
SEROGROUP
(%)
(50)
(9)
0
(0)
0
(0)
0
(0)
0
(0)
9 (41)
22 (100)
No.
19
0
(%)
(63)
(0)
1
(3)
0
(0)
0
(0)
0
(0)
10 (33)
30 (100)
Serogroup
B
C
Y
W135
X
Z
Not groupable
Unknown
TOTAL
No. (%)
6 (27)
9 (41)
6 (27)
0
(0)
0
(0)
0
(0)
1
(5)
0
(0)
22 (100)
No. (%)
13 (43)
13 (43)
2
(7)
1
(3)
0
(0)
1
(3)
0
(0)
0
(0)
30 (100)
Cases of Neisseria meningitidis Invasive
Disease by Culture Date, Minnesota
January 1, 2007 – December 31, 2008
Serogroup B
Serogroup C
Number of Cases
Serogroup Y
12
Serogroup Z
10
Serogroup W135
Not Groupable/Unk
8
Death
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O
2007
2008
Month of Culture
N D
TABLE 3
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
1/1/200812/31/2008
1/1/200712/31/2007
OUTCOME
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
(%)
41 (50)
41 (50)
82 (100)
No.
(%)
31 (43)
41 (57)
72 (100)
No.
(%)
6
(7)
6
(7)
0
(0)
1
(1)
1
(1)
2
(2)
4
(5)
11 (13)
14 (17)
37 (45)
82 (100)
No.
(%)
8 (11)
4
(6)
0
(0)
1
(1)
3
(4)
2
(3)
6
(8)
4
(6)
13 (18)
31 (43)
72 (100)
No.
(%)
43 (52)
39 (48)
82 (100)
No.
(%)
31 (43)
41 (57)
72 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Other Only
Unknown
TOTAL
No.
(%)
73 (89)
9 (11)
82 (100)
No.
(%)
64 (89)
8 (11)
72 (100)
No.
53
3
Site
Blood
CSF
Peritoneal
Joint
Pleural fluid
Other
TOTAL
No.
(%)
75 (91)
5
(6)
0
(0)
0
(0)
1
(1)
1
(1)
82 (100)
No.
(%)
65 (90)
2
(3)
0
(0)
1
(1)
3
(4)
1
(1)
72 (100)
TYPE OF INFECTION
GENDER
Gender
Male
Female
TOTAL
Survived
Yes
No
TOTAL
SITE OF ISOLATE CULTURE
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
1/1/200812/31/2008
(%)
(65)
(4)
1
(1)
0
(0)
1
(1)
0
(0)
24 (29)
82 (100)
No.
52
5
(%)
(72)
(7)
0
(0)
1
(1)
0
(0)
0
(0)
14 (19)
72 (100)
Type
Bacteremia
Pneumonia
Meningitis
Cellulitis
Peritonitis
Epiglottitis
Chorioamnionitis
Arthritis
Sinusitis
Other
TOTAL
No.
(%)
36 (44)
37 (45)
5
(6)
0
(0)
0
(0)
1
(1)
0
(0)
0
(0)
0
(0)
3
(4)
82 (100)
No.
(%)
29 (40)
26 (36)
6
(8)
2
(3)
0
(0)
2
(3)
0
(0)
1
(1)
0
(0)
6
(8)
72 (100)
TABLE 3 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
HAEMOPHILUS INFLUENZAE , JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
1/1/200812/31/2008
ISOLATE SEROTYPE
Type
a
b
c
d
e
f
Non-typeable
TOTAL
No.
4
1
1
2
4
8
53
73
(%)
(5)
(1)
(1)
(3)
(5)
(11)
(73)
(100)
No.
2
5
0
1
4
12
42
66
(%)
(3)
(8)
(0)
(2)
(6)
(18)
(64)
(100)
Not Tested
No.
9
(%)*
(16)
No.
5
(%)*
(9)
SEROTYPE B (Hib) CASES BY AGE
Age (Years)
<1
1-4
5-9
10-14
15-19
20-39
40-59
60+
TOTAL
*of total cases
No.
0
1
0
0
0
0
0
0
1
(%)
(0)
(100)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
No.
2
3
0
0
0
0
0
0
5
(%)
(40)
(60)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
Cases of Haemophilus influenzae Invasive
Disease by Culture Date, Minnesota
January 1, 2007 – December 31, 2008
Type b
Death
Number of Cases
12
10
8
6
4
2
0
J F M A M J
J A S O N D J F M A M J J A S O N D
2008
2007
Month of Culture
TABLE 4
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
RESIDENCE
Residence
No.
(%)
Twin Cities Metro Area
94
(54)
Greater Minnesota
79
(46)
173
(100)
TOTAL
1/1/2000812/31/2008
No. (%)
104 (56)
81 (44)
185 (100)
AGE
Age (Years)
<1
1-4
5-9
10-19
20-29
30-39
40-49
50-59
60-69
70+
TOTAL
No.
7
8
10
9
11
12
26
27
24
39
173
(%)
(4)
(5)
(6)
(5)
(6)
(7)
(15)
(16)
(14)
(23)
(100)
No. (%)
3
(2)
12
(6)
15
(8)
10
(5)
8
(4)
12
(6)
36 (19)
27 (15)
21 (11)
41 (22)
185 (100)
(%)
(49)
(51)
(100)
No. (%)
111 (60)
74 (40)
185 (100)
GENDER
Gender
Male
Female
TOTAL
No.
84
89
173
RACE
Race
White
Black
American Indian/
Alaskan Native
Asian/Pacific Islander
More than One Race
Unknown
TOTAL
No.
113
7
(%)
(65)
(4)
No.
132
9
(%)
(71)
(5)
4
3
0
46
173
(2)
(2)
(0)
(27)
100
2
4
0
38
185
(1)
(2)
(0)
(21)
100
1/1/200712/31/2007
1/1/200812/31/2008
SITE OF ISOLATE CULTURE
Site
No. (%)
No. (%)
Blood only
105 (61) 111 (60)
CSF only
2
(1)
0
(0)
Blood and other
25 (14)
22 (12)
Joint
11
(6)
16
(9)
Peritoneal
2
(1)
2
(1)
Pericardial
0
(0)
0
(0)
Pleural
6
(3)
5
(3)
Middle ear
0
(0)
0
(0)
Bone
4
(2)
1
(1)
Muscle
2
(1)
3
(2)
Internal Body Site
4
(2)
3
(2)
Other sterile site
12
(7)
22 (12)
TOTAL
173 (100) 185 (100)
TYPE OF INFECTION
Type
No. (%)
Bacteremia only
59 (34)
Meningitis
1
(1)
Pneumonia only
16
(9)
Cellulitis only
27 (16)
Necrotizing fasciitis
(NF) only
10
(6)
Otitis
1
(1)
Arthritis only
10
(6)
Osteomyelitis
5
(3)
Endometritis
2
(1)
Abscess
5
(3)
Empyema/Peritonitis
2
(1)
Endocarditis
0
(0)
STSS
0
(0)
Pneumonia + other
6
(3)
NF + other
4
(2)
Cellulitis + other
11
(6)
Abscess + other
2
(1)
Other/Unknown (2)
12
(7)
TOTAL
173 (100)
No.
54
0
15
27
(%)
(29)
(0)
(8)
(15)
7
(4)
1
(1)
9
(5)
4
(2)
2
(1)
3
(2)
2
(1)
0
(0)
3
(2)
11
(6)
6
(3)
13
(7)
1
(1)
27 (15)
185 (100)
TABLE 4 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP A STREPTOCOCCUS, JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
1/1/200812/31/2008
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
157
16
0
173
(%)
(91)
(9)
(0)
(100)
No.
165
20
0
185
(%)
(89)
(11)
(0)
(100)
No.
10
1
0
0
1
5
0
0
1
1
0
1
20
(%)
(50)
(5)
(0)
(0)
(5)
(25)
(0)
(0)
(5)
(5)
(0)
(5)
(100)
TYPE OF INFECTION
RESULTING IN DEATH
Type
Bacteremia
Bloodstream/CSF Infection
Meningitis
Necrotizing fasciitis
Pneumonia
Cellulitis
Peritonitis
Pneumonia/Cellulitis
Pneumonia/Otitis Media
Abscess
Petechia/Vasculitis
Unknown
TOTAL
No.
8
0
0
2
2
0
1
1
0
0
0
2
16
(%)
(50)
(0)
(0)
(13)
(13)
(0)
(6)
(6)
(0)
(0)
(0)
(13)
(100)
Cases of Invasive Group A Streptococcal Disease
by Date of Culture, Minnesota
January 1, 2007 – December 31, 2008
Death
18
Number of Cases
16
14
12
10
8
6
4
2
0
Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec
2007
2008
Date of Culture
TABLE 5
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
1/1/200712/31/2007
1/1/200812/31/2008
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
(%)
170 (51)
162 (49)
332 (100)
OUTCOME
No. (%)
240 (57)
178 (43)
418 (100)
AGE
Age
<7 days
7-90 days
91 days-11 mos.
1-9 yrs
10-19 yrs
20-29 yrs
30-39 yrs
40-49 yrs
50-59 yrs
60-69 yrs
70+ yrs
TOTAL
No.
(%)
23
(7)
13
(4)
1
(0)
2
(1)
4
(1)
14
(4)
24
(7)
30
(9)
55 (17)
59 (18)
107 (32)
332 (100)
No.
(%)
187 (56)
145 (44)
332 (100)
No. (%)
23
(6)
20
(5)
2
(0)
2
(0)
4
(1)
16
(4)
29
(7)
29
(7)
75 (18)
75 (18)
143 (34)
418 (100)
No.
(%)
209 (63)
15
(5)
5
(2)
5
(2)
2
(1)
96 (29)
332 (100)
No. (%)
319 (96)
12
(4)
1
(0)
332 (100)
No. (%)
393 (94)
24
(6)
1
(0)
418 (100)
Site
Blood only
CSF only
Blood and CSF
Pleural
Joint
Placenta
Amniotic fluid
Surgical specimen
Internal body site
Peritoneal
Bone
Other
TOTAL
No. (%)
261 (79)
3
(1)
0
(0)
0
(0)
25
(8)
4
(1)
1
(0)
0
(0)
3
(1)
4
(1)
27
(8)
4
(1)
332 (100)
No. (%)
292 (70)
9
(2)
0
(0)
4
(1)
46 (11)
6
(1)
0
(0)
0
(0)
0
(0)
13
(3)
46 (11)
2
(0)
418 (100)
TYPE OF INFECTION
No. (%)
221 (53)
197 (47)
418 (100)
RACE
Race
White
Black
Amer Indian/Alas Native
Asian/Pacific Islander
More than 1 race
Other/Unknown
TOTAL
Survived
Yes
No
Unknown
TOTAL
SITE OF ISOLATE CULTURE
GENDER
Gender
Male
Female
TOTAL
1/1/200812/31/2008
No. (%)
277 (66)
30
(7)
11
(3)
3
(1)
0
(0)
97 (23)
418 (100)
Type
Bacteremia
Meningitis
Pneumonia
Cellulitis
Arthritis
Osteomyelitis
Abscess
Necrotizing fasciitis
Peritonitis
Septic abortion
or stillbirth
Other
TOTAL
No.
156
5
27
52
21
28
12
1
2
2
(%)
(47)
(2)
(8)
(16)
(6)
(8)
(4)
(0)
(1)
(1)
26
(8)
332 (100)
No.
172
6
34
56
38
50
17
2
7
1
(%)
(41)
(1)
(8)
(13)
(9)
(12)
(4)
(0)
(2)
(0)
35
(8)
418 (100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2007 - DECEMBER 31, 2008
EARLY ONSET CASES*
1/1/200712/31/2007
LATE ONSET CASES*
1/1/200812/31/2008
1/1/200712/31/2007
1/1/200812/31/2008
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
No.
14
9
23
(%)
(61)
(39)
(100)
No.
12
11
23
(%)
(52)
(48)
(100)
No.
8
5
13
(%)
(62)
(38)
(100)
No.
15
5
20
(%)
(75)
(25)
(100)
No.
5
8
13
(%)
(38)
(62)
(100)
No.
10
10
20
(%)
(50)
(50)
(100)
GENDER
Gender
Male
Female
TOTAL
No.
14
9
23
(%)
(61)
(39)
(100)
No.
9
14
23
(%)
(39)
(61)
(100)
RACE
Race
White
Black
American Indian/
Alaskan Native
More than 1 race
Asian/Pacific Islander
Other/Unknown
TOTAL
No.
11
3
(%)
(48)
(13)
No.
16
6
(%)
(70)
(26)
No.
3
5
(%)
(23)
(38)
No.
10
7
(%)
(50)
(35)
0
1
1
7
23
(0)
(4)
(4)
(30)
(100)
0
0
0
1
23
(0)
(0)
(0)
(4)
(100)
0
0
0
5
13
(0)
(0)
(0)
(38)
(100)
1
0
0
2
20
(5)
(0)
(0)
(10)
(100)
No.
13
0
0
13
(%)
(100)
(0)
(0)
(100)
No.
20
0
0
20
(%)
(100)
(0)
(0)
(100)
(%)
(77)
(15)
(0)
(8)
(100)
No.
16
4
0
0
20
(%)
(80)
(20)
(0)
(0)
(100)
OUTCOME
Survived
Yes
No
Unknown
TOTAL
No.
21
2
0
23
(%)
(91)
(9)
(0)
(100)
No.
21
2
0
23
(%)
(91)
(9)
(0)
(100)
TYPE OF INFECTION
Type
Bacteremia
Meningitis
Pneumonia
Other
TOTAL
No.
19
1
1
2
23
(%)
(83)
(4)
(4)
(9)
(100)
No.
19
1
0
3
23
(%)
(83)
(4)
(0)
(13)
(100)
No.
10
2
0
1
13
* Early onset is defined as occurring in the first 6 days, and late onset in the 7th-89th days of life.
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
1/1/200812/31/2008
TYPE OF CASE
Type of Case*
Maternal case - miscarriage/stillbirth
Maternal case - other
Infant case - early onset
Infant case - late onset
Adult/Child, non-maternal, non-infant case
TOTAL
No.
5
5
23
13
286
332
(%)
(2)
(2)
(7)
(4)
(86)
(100)
No.
1
1
23
20
373
418
(%)
(0)
(0)
(6)
(5)
(89)
(100)
*A maternal case is defined as invasive GBS infection during pregnancy or postpartum. An early onset infant case
is defined as invasive disease occurring in the first 6 days, and late onset in the 7th - 89th days of life.
TYPE OF INFECTION REPORTED FOR MATERNAL CASES
Type
Bacteremia without another focus of infection
Septic abortion/ stillbirth
Meningitis
Chorioamnionitis
Abscess
Pyelonenephritis
Peritonitis
Cellulitis
Arthritis
Endometritis
Unknown
TOTAL
No.
2
2
0
2
0
0
0
1
1
1
1
10
(%)
(20)
(20)
(0)
(20)
(0)
(0)
(0)
(10)
(10)
(10)
(10)
(100)
No.
2
0
0
0
0
0
0
0
0
0
0
2
(%)
(100)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(0)
(100)
No.
1
0
0
1
0
2
(%)
(50)
(0)
(0)
(50)
(0)
(100)
OUTCOME OF FETUS FOR MATERNAL CASES
Outcome
Survived, no apparent clinical illness
Survived, clinical illness
Live birth, neonatal death, GBS-related
Miscarriage/stillbirth, likely GBS-related
Induced abortion
TOTAL
No.
4
0
0
5
1
10
(%)
(40)
(0)
(0)
(50)
(10)
(100)
TABLE 5 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
GROUP B STREPTOCOCCUS, JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/200712/31/2007
1/1/200812/31/2008
SITE OF ISOLATE CULTURE FOR MISCARRIAGES/STILLBIRTHS
Site
Maternal blood
CSF
Amniotic fluid
Placenta
Peritoneal
Autopsy
TOTAL
No.
0
0
1
4
0
0
5
(%)
(0)
(0)
(20)
(80)
(0)
(0)
(100)
No.
1
0
0
0
0
0
1
(%)
(100)
(0)
(0)
(0)
(0)
(0)
(100)
GESTATIONAL AGE OF EARLY ONSET CASES
Age (weeks)
<28
28-32
33-34
35-36
37+
Unknown
TOTAL
No.
4
2
1
3
13
0
23
(%)
(17)
(9)
(4)
(13)
(57)
(0)
(100)
No.
5
1
0
1
16
0
23
(%)
(22)
(4)
(0)
(4)
(70)
(0)
(100)
BIRTH WEIGHT OF EARLY ONSET CASES
Weight (grams)
<1000
1000-1999
2000-2999
>3000+
Unknown
TOTAL
No.
0
0
4
16
3
23
(%)
(0)
(0)
(17)
(70)
(13)
(100)
No.
4
3
2
14
0
23
(%)
(17)
(13)
(9)
(61)
(0)
(100)
Cases of Group B Stretococcal Disease by Date Cultures, Minnesota
January 1, 2007 – December 31, 2008
2007
2008
50
45
40
35
25
20
15
10
5
2007
Month of Culture
2008
D
ec
N
ov
ct
O
Se
p
l
A
ug
Ju
n
Ju
M
ay
A
pr
M
ar
Fe
b
Ja
n
D
ec
N
ov
ct
O
Se
p
A
ug
l
Ju
n
Ju
M
ay
A
pr
M
ar
Fe
b
0
Ja
n
Number of Cases
30
TABLE 6
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE , JANUARY 1, 2007 - DECEMBER 31, 2008
1/1/2007- 1/1/200812/31/2007 12/31/2008
1/1/20071/1/200812/31/2007 12/31/2008
RESIDENCE
Residence
Twin Cities Metro Area
Greater Minnesota
TOTAL
OUTCOME
No. (%)
318 (48)
346 (52)
664 (100)
No. (%)
330 (46)
382 (54)
712 (100)
AGE
No. (%)
27
(4)
28
(4)
28
(4)
26
(4)
44
(6)
116 (16)
180 (25)
145 (20)
118 (17)
712 (100)
Culture Site
Blood Only
Blood and CSF
CSF Only
Pericardial Fluid
Pleural
Joint
Peritoneal
Other
TOTAL
GENDER
No. (%)
357 (50)
355 (50)
712 (100)
RACE
Race
White Only
Black Only
American Indian/
Alaskan Native Only
Asian/Pacific Isl. Only
More than 1 Race
Unknown
TOTAL
* of total cases
No.
379
38
(%)
(91)
(9)
(9)
No. (%)
649 (91)
63
(9)
712 (100)
No. (%)
617 (93)
0 (<1)
25
(3)
0 (<1)
14
(2)
3
(1)
1 (<1)
4 (<1)
664 (100)
No. (%)
661 (93)
0
(0)
25
(4)
0 (<1)
15
(2)
5
(1)
3 (<1)
3 (<1)
712 (100)
TYPE OF INFECTION
No. (%)
349 (53)
315 (47)
664 (100)
Gender
Male
Female
TOTAL
No.
603
61
664
SITE OF ISOLATE CULTURE
No. (%)
39
(6)
30
(5)
33
(5)
29
(4)
32
(5)
102 (15)
150 (23)
123 (19)
126 (19)
664 (100)
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
Survived
Yes
No
TOTAL
(%) No.
(59) 446
(8) 58
(%)
(62)
(8)
Type
Bacteremia
without focus
Pneumonia
Meningitis
Otitis
Cellulitis
Other
TOTAL
No.
(%)
206 (35)
381 (54)
38
(5)
12 (<1)
2
(1)
25
(4)
664 (100)
No.
(%)
221 (31)
410 (58)
35
(5)
3
(0)
3
(0)
40
(6)
712 (100)
PENICILLIN SUSCEPTIBILITY
13
(<1)
15
(<1)
10
(<1)
209 (31)
664 (100)
23
(3)
13
(2)
0
(0)
174 (24)
714 (100)
Susceptibility
Susceptible (MIC < 0.06)
Resistant (MIC ≥ 0.12)
TOTAL
No. (%)
492 (80)
123 (20)
615 (100)
No. (%)
529 (80)
130 (20)
659 (100)
Not Tested
No. (%)*
57
(9)
No. (%)*
53
(7)
TABLE 6 (CONTINUED)
REPORTED CASES OF INVASIVE DISEASE ATTRIBUTED TO
STREPTOCOCCUS PNEUMONIAE WITH SUSCEPTIBILITY TESTING COMPLETED,
JANUARY 1, 2007 - DECEMBER 31, 2008
PENICILLIN RESISTANCE* BY AGE
1/1/200712/31/2007
Age (Years)
<1
1
2-4
5-17
18-34
35-49
50-64
65-79
80+
TOTAL
Resistant
Total
9 / 37
9 / 29
11 / 30
4 / 27
2 / 26
11 / 94
23 / 141
28 / 116
26 / 115
123 / 615
1/1/200812/31/2008
(%)
(24)
(31)
(37)
(15)
(8)
(12)
(16)
(24)
(23)
(20)
4
10
10
3
2
15
28
36
22
130
Resistant
Total
(%)
/ 27
(15)
/ 26
(38)
/ 27
(37)
/ 24
(13)
/ 40
(5)
/ 106
(14)
/ 166
(17)
/ 134
(27)
/ 109
(20)
/ 659
(20)
PENICILLIN RESISTANCE* BY TYPE OF INFECTION
1/1/200712/31/2007
Type
Bacteremia
Pneumonia
Meningitis
Other/Unknown
TOTAL
Resistant
Total
42 / 190
66 / 352
4 / 37
11 / 36
123 / 615
1/1/200812/31/2008
(%)
(22)
(19)
(11)
(31)
(20)
Resistant
Total
(%)
54 / 221
(24)
63 / 410
(15)
4 / 35
(11)
9 / 46
(20)
130 / 712
(18)
*Penicillin resistant (meningitis breakpoints) includes isolates with a MIC > 0.12 µg/ml.
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1 - December 31, 2007
30
28
Total cases = 664
Total cases with isolates submitted to MDH = 615
26
Number of Cases
24
22
Penicillin Resistant
20
Death
18
16
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
2007 Week of Culture
* Penicillin resistant (meningitis break points) includes isolates with a MIC > 0.12 µg/ml
Nov
Dec
Cases of S. pneumoniae by Week of Culture,
Minnesota, January 1 - December 31, 2008
30
28
Total cases = 712
Total cases with isolates submitted to MDH = 664
26
Number of Cases
24
22
Penicillin Resistant
20
Death
18
16
14
12
10
8
6
4
2
0
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
2008 Week of Culture
* Penicillin resistant (meningitis break points) includes isolates with a MIC > 0.12 µg/ml
Nov
Dec