Winning Formula

Clinpro Tooth Crème
™
0.21% w/w Sodium Fluoride
Anti-Cavity Paste with Tri-Calcium Phosphate
Winning Formula
Helps Prevent Cavities
With Innovative
Tri-Calcium
Phosphate
Exclusively From 3M ESPE
Clinpro
Tooth Crème
™
Introducing Clinpro Tooth Crème,
the winning formula that helps
prevent cavities.
™
Strengthens teeth and reverses white spot
lesions better than the leading brand
Clinpro Tooth Crème 0.21% w/w Sodium Fluoride Anti-Cavity Paste is an advanced
™
formula containing an innovative tri-calcium phosphate ingredient and is available
exclusively from 3M ESPE. This winning formula is a one-step process requiring patients to
simply brush with it once daily, eliminating the two-step regimen currently associated with
another leading topical creme with calcium, phosphate and fluoride. Clinpro Tooth Crème
delivers more fluoride, helps strengthen enamel and helps reverse white spot lesions
better than a leading 900 ppm fluoride topical creme containing calcium phosphate.
% Change in Surface
Microhardness [Mean +/- SEM]
Fluoride Uptake
[Mean +/- SEM]
1
1
Summary of Advantages:
• Delivers more fluoride to
the tooth
• Strengthens teeth better than
the leading brand
• Reverses white spots better
than the leading brand
140%
40
120%
35
30
% change in SMH
micrograms F / surface of enamel
45
25
20
15
10
80%
60%
40%
20%
5
0
100%
0%
Topical Creme
Clinpro Tooth Crème
with Calcium Phosphate 0.21% w/w Sodium
(900 ppm F-)
Fluoride Paste
Clinpro Tooth Crème 0.21% w/w
Sodium Fluoride Anti-Cavity Paste
delivers more fluoride to the tooth!
™
Topical Creme
with Calcium Phosphate
(900 ppm F-)
Clinpro Tooth Crème
0.21% w/w Sodium
Fluoride Paste
Clinpro Tooth Crème 0.21% w/w
Sodium Fluoride Anti-Cavity Paste
strengthens teeth better!
™
• Prevents cavities
• Reduces root cavities
• Contains 0.21% w/w
(950 ppm fluoride ion)
Clinpro Tooth Crème 0.21% w/w Sodium Fluoride
Anti-Cavity Paste with Tri-Calcium Phosphate
™
• Contains an innovative
calcium and phosphate
ingredient
Item #
12216
Clinpro™ Tooth Crème 0.21% Sodium Fluoride
Anti-Cavity Paste with Tri-Calcium Phosphate
113g tube, vanilla mint flavor
• Gentle, effective cleaning
• Cleans and whitens teeth
• Low abrasion
• Replaces conventional
toothpaste regimen
• Available in a convenient
113g flip-top tube
Product Information
1. 3M internal data on file.
A better option
FF-
CaOn
Ca
The optimized formula makes Clinpro Tooth Crème an outstanding choice. It contains fluoride
CaO
C
aOn
CaO
C
aO
as well as calcium and phosphate, which are components naturally found in saliva. This
F-
F-
FF-
CaOn
Ca
CaO
C
aOn
barrier is created around the calcium allowing it to coexist with the fluoride ions. As Clinpro
CaO
C
On
F-
CaO
Ca
On
CaO
CaO
On
CaO
C
aO
On
CaOn
Ca
F-
CaO
aOn
C n
CaO
Tooth Crème comes in contact with saliva during brushing, the barrier breaks down and makes
F-
CaO
C
aOn
CaO
On
F-
proprietary formula successfully integrates these components, enhancing, rather than
compromising, the product’s performance. During the manufacturing process, a protective
CaO
C
Ca
aO
On
CaO
O
CaO
Ca
CaO
CaO
O
FF-
the calcium, phosphate and fluoride readily available to the tooth. The tooth naturally absorbs
these components, helping to prevent the initiation and further progression of demineralization
and allowing remineralization to occur.
F-
FCaOn
Ca
F-
Teamwork for better results
CaO
Ca
On
Ca n
CaO
CaO
C
aOn
CaO
aOn
CaOn
CaO
Ca
On
CaOn
CaOn
F-
FCaOn
C n
CaO
CaO
C
aO
On
CaO
Ca
aOn
aO
F-
CaO
On
CaO
Ca
aO
On
CaOn
CaOn
is the result of a relationship between 3M ESPE and Indiana Nanotech scientists. 3M ESPE
CaOn
F-
FF-
The development of this exceptional 950 ppm fluoride and tri-calcium phosphate formula
CaOn
CaO
C
Ca
aOn
CaOn
F-
CaOn
C
F-
enlisted world-renowned and expert caries researchers to become part of the development
team. Key players included Dr. George Stookey, a pioneer in caries research and key
contributor to developing the world’s first clinically proven fluoride toothpaste, Dr. Robert
Karlinsey, an emerging leader in developing dental and biomedical technology applications,
and the 3M ESPE Preventive Research Team led by Aaron Pfarrer.
Discover the benefits
Practicing dental professionals and industry
experts alike will discover the breakthrough
benefits of Clinpro Tooth Crème. Your patients
should, too. The winning formula for caries
prevention is now available.
Patient compliance can be a
challenge. Dispensing Clinpro
Tooth Crème 0.21% w/w Sodium
Fluoride Anti-Cavity Paste from
your office is good for your
patients and your practice.
™
Saliva activates the calcium compound,
breaking down the protective coating and
making it available to the tooth.
Dental Products
3M Region
3M Center
Building 275-2SE-03
St. Paul, MN 55144-1000
U.S.A.
1-800-634-2249
Address
Address
Address
Address
Address
Please recycle. Printed in XXXXX.
© 3M 2008. All rights reserved.
70-0000-0000-0
3M, ESPE and Clinpro are trademarks
of 3M or 3M ESPE AG.