Chapter 1 The Reproductive System Dr. Areefa Al Bahri Assistance professor Nursing college- midwifery departmentIslamic university of Gaza Anatomy of the Male Reproductive System The importance of the reproductive system is the production of off spring & continued existence of the genetic code. The male reproductive system, like that of the female, consists of those organs functioning to produce a new individual. The male organs are specialized to produce and maintain the male sex cells, or sperm; to transport them, along with supporting fluids, to the female reproductive system; and to secret the male hormone testosterone. The Male reproductive organs include the two testes (Where the sperm cells and testosterone are made), the penis, the scrotum, and the Accessory organ (epididymis, vas deferens, seminal vesicles, ejaculatory duct, urethra, bulbourethral glands, and prostate gland). The Reproductive System Gonads – primary sex organs Testes in males Ovaries in females Gonads produce gametes (sex cells) and secrete hormones Sperm – male gametes Ova (eggs) – female gametes Male Reproductive System Testes Duct system Epididymis Ductus deferens Urethra Male Reproductive System Accessory organs Seminal vesicle Prostate gland Bulbourethral gland External genitalia Penis Scrotum Testes Coverings of the testes Tunica albuginea – capsule that surrounds each testis Testes Coverings of the testes (continued) Septa – extensions of the capsule that extend into the testis and divide it into lobules Testes Each lobule contains one to four seminiferous tubules Tightly coiled structures Function as sperm-forming factories Empty sperm into the rete testis Sperm travels through the rete testis to the epididymis Interstitial cells produce androgens such as testosterone The functions of testes are: Spermatogenesis which is formation of mature male gametes by seminiferous tubules (cells divide first by the process of mitosis). Secretion of hormone (testosterone) by interstitial cells. Epididymis Comma-shaped, tightly coiled tube It is one of the ducts systems (they convey sperms to the vas deferens) Functions to mature and store sperm cells (up to 30 days) Expels sperm with the contraction of muscles in the epididymis walls to the vas deferens Maturation of the sperm which stays 1-3 weeks in this segment. Secretion of a small part of the seminal fluid. Vas deferens: It's the extension of the tail of the epididymis. It passes up in the inguinal canal to the top of the urinary bladder, to join the seminal duct, forming the ejaculatory duct. Function: Ductal system connects the epididymis with ejaculatory duct. The storage time is about 30 days & the sperm will not loose their fertility power. Ejaculatory duct: Both ducts are short tubes. Pass through the prostate gland to terminate in urethra and they carry the spermatozoa and the seminal fluid. Each is formed of the union of vas deferens & seminal vesicle. Accessory Reproductive Glands Seminal vesicles: They are two pouches, lies along the lower part of the posterior surface of the bladder, directly in front of the rectum. Functions: Secretion of an alkaline viscous liquid component of the semen (it accounts for 60% of semen volume). It contains fructose which is considered an energy source for sperm motility after ejaculation. Contains alkaline prostaglandin to help neutralize semen pH Prostate gland: Functions: It secretes a thin, milky, alkaline fluid that is rich in zinc, citric acid, acid phosphatase, and calcium which accounts for 30% of the seminal fluid. Its alkalinity protects the sperm from the acidity of the male urethra & female vagina. Bulbourethral glands: Cowper's glands are small peas in size & shape. They are just below the prostate and around the penile part of urethra. Functions: Secretion of an alkaline fluid. Secretion of mucous which is lubricant for urethra. Supporting Structure 1. Scrotum: provide the optimum temperature for testes for proper spermatogenesis 2. Spermatic cord: It's a fibrous covering of the vas deferens, blood vessels, lymph vessels & nerves. It extends from the top of the testis along the inguinal canal, up to the internal inguinal ring. 3. penis The female reproductive system produces the female reproductive cells (the eggs, or ova and contains an organ (uterus) in which development of the fetus takes place. The system includes Ovaries Duct System Uterine tubes (fallopian tubes) Uterus Vagina External genitalia Female Reproductive System Female Reproductive System Female pelvic Types of pelvic Function • Allows movement of the body, especially walking and running. • Helps in child bearing • Protect the pelvic organ. • Pelvic floor responsible for voluntary control of micturition and play an important part in sexual intercourse. • Allows exit to the fetus Ovaries Both ovaries are nodular glands, like large almonds in size & shape. • Attached to the posterior surface of the broad ligament. • The end of the uterine tube cup is over it without actual attachment Functions: 1. Oogenesis (egg production). 2. Endocrine function ovaries are the source of the female sex hormones (estrogen & progesterone) which are essential hormones in menstrual cycle & pregnancy. Uterus It is centrally located in the pelvic cavity between the bladder (anteriorly) and rectum (posteriorly). In unmarried woman, the uterus is pear shaped, measures approximately 7.5 cm length, 5 cm in width, and 2.5 cm in thickness. The upper part is called the body, the bulging upper part of the body is called the fundus & the lower part is called the cervix (neck). Uterine wall 1. Endometrium: is the innermost layer • It is composed of three layers, and of these, two are shed with each menses. 2. Myometrium: • It's the thick middle layer. • The fundus has the thickest part of myometrium. • It is composed of layers of smooth muscle that extend in three directions—longitudinal, transverse, and oblique. 3. Parietal peritoneum: • It's the outermost layer. • It covers all the parts except the lower fourth of the anterior surface & the cervix. Uterine cavity: • The cavity is small because of the thick wall. • It's flat & triangular. • The base is upward & its apex is downward, constitutes the cervical internal os which opens into the cervical canal which narrows on its lower end forming the external os which opens into the vagina. Functions of the uterus: • Nutritional source until the placental develops. • Provides a safe environment that protects /fetus • Labor. • Menstruation. • Pregnancy site. Uterine (Fallopian) Tubes o Each one is about 10 cm long, attached to the outer upper angle of the uterus. o The diameter of each tube is approximately 6 mm. o It consists of 3divisions: o The isthmus: the closest part to the uterus. Tubal ligation done here. o Ampulla: is the middle fertilization takes place here. o Infundibulum: Is the funnelshaped portion located at the distal end of the fallopian tube. Uterine (Fallopian) Tubes Receive the ovulated oocyte Provide a site for fertilization Attaches to the uterus Does not physically attach to the ovary Supported by the broad ligament Vagina – It's a collaps-able tube, 7-10 cm long. – It presents between the bladder & urethra (anteriorly) & the rectum (posteriorly). – It connects the uterus with the perennial opening. Functions: Receives the sperms during the sexual intercourse. Birth canal. Transports tissue and blood during menses to the outside, External Genitalia (Vulva) Mons pubis Fatty area overlying the pubic symphysis Covered with pubic hair after puberty Figure 16.9 External Genitalia (Vulva) Labia – skin folds Labia majora Labia minora Figure 16.9 Urinary meatus (urethral orifice): is a small opening of the urethra, between clitoris & vaginal orifice. Greater vestibular gland (bartholin's gland): It's bean-shaped, one on each side of the vaginal orifice. Each opens by a long duct in a space between labia minora & the hymen and they secrete mucus which lubricates the vaginal opening. Hymen A small portion of tissue surrounds the opening of the vagina. Hymnal tissue does not completely cover or occlude the vagina. the hymen becomes widened, sometimes by tearing, which may be accompanied by bleeding. Breast Breast Breast tissue is formed of two major organs: Mammary systems: which include : Lactating glands: which are formed of distal alveoli, forming lobules, united to form lobes, arranged in grape like clusters. Ductal system: The ducts from the various lobules unite forming a single lactiferous (milk carrying) duct for each lobe, each enlarges slightly before reaching the nipple into small lactiferous sinuses, each duct terminates in a tiny opening on the surface of the nipple • Breast function: • The function of the breast is lactation, the factors affecting milk production are: • Estrogen hormones promote the ductal growth. • Progestrone stimulates the alveolar system. • Prolactin stimulates milk secretion. • Oxytocin stimulates milk ejection from the breast. • Ovarian Cycle: • Before birth, the ovarian tissue begins a meiosis division; it reduces the number of chromosomes in the daughter cell by half. • When a child is born, her ovaries contain many primary follicles, each contains an oocytes that have temporarily suspended the meiotic process before it's complete, once each month, on about the first day of menstruation, the oocytes within many primary follicles resume meiosis, one of them matures & migrates to the surface of the ovary, to be expelled from the ruptured wall of the mature follicle during ovulation. Oogenesis The total supply of eggs are present at birth Ability to release eggs begins at puberty Reproductive ability ends at menopause Oocytes are matured in developing ovarian follicles Oogonia – female stem cells found in a developing fetus Oogonia undergo mitosis to produce primary oocytes Primary oocytes are surrounded by cells that form primary follicles in the ovary Primary oocytes are inactive until puberty Follicle stimulating hormone (FSH) causes some primary follicles to mature Meiosis starts inside maturing follicle Meiosis is completed after ovulation only if sperm penetrates Figure 16.10 Oogenesis Ovarian Cycle: • When a child is born, her ovaries contain many primary follicles, • At puberty , the oocytes within many primary follicles resume meiosis, one of them matures & migrates to the surface of the ovary, to be expelled from the ruptured wall of the mature follicle during ovulation. • Ovulation usually occurs 14 days before the next menstrual period begins. • Immediately after ovulation, cells of the ruptured follicle enlarged & transformed into a golden colored body which called corpus luteum. • The corpus luteum remain for 7-8 days, & secrete high amount of progesterone.Then the corpus luteum will be nonfunctioning white scar, called corpus albicans which moves to the center of the ovary & finally disappears. Endometrial (menstrual) cycle: • During menstruation, parts spongy layers of the endometrium slough off, leaving denuded areas. • After menstruation, this cell layer will proliferate causing the endometrium to reach a thickness of 2-3 mm by the time of ovulation. • A day before menstruation starts again, a drop in progesterone level causes contraction of the muscle layer of the arteries producing endometrial ischemia, leading to the death of the tissue, and sloughing of the endometrium (bleeding). menstrual cycle phases: 1. Menses: occurs on days 1-5 of a new cycle. 2. Postmenstrual phase described as " preovulatory phase" it starts from the 6th to 13th day of a 28 days-cycle. This period is called estrogenic or follicular or proliferative phase. 3. Ovulation: occurs on cycle day 14 in a 28- day cycle. 4. Premenstrual phase (postovulatory) between ovulation & the onset of menses, it's secretory or luteal phase so progesterone will be secreted, it takes from 14 days to 28 in a 28-day cycle. Hormonal Control of the Ovarian and Uterine Cycles menses Function estrogen during the post menstrual phase • • • • Proliferation of the endometrium cells. Growth of the endometrial glands. Increase in endometrium water content. Increase in myometrial contraction. Function progesterone during the premenstrual phase 1. Increase secretion by endometrial glands. 2. Increase in the endometrium water content. 3. Decrease in myometrial contraction.
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