Dave: Speaker2: Dave: Ifyou'rearegularlistening,you'veheardmesharemylistoftoptenbiohacks.Let'stalk aboutnumbernine;funhacksforthebulletproofmind.Itmaysoundweird,buthanging upsidedownisagreatwaytohackyourbrain.Regularlyinvertingtrainsyourbrain capillaries,makingthemstrongerandmorecapabletobringoxygentoyourbrain.It's prettystraightforward.Moreoxygeninthebrainmeansbetterperformance. IgetmydailystretchandmydoseofoxygenwithmyTeeterInversionTable,whichisso essentialforoptimumfocus,concentrationandmentalenergy.Thatfullbodystretch elongatesthespineandtakesthepressureoffthediscs,sotheycanplumbackup.Less pressuremeanslesspain.Ifyouhavebackpain,evenifyou'vebeenluckyenoughto avoiditsofar,youreallywantateetertoinverteverydaytokeepyourbackandjoints feelinggreat. Forover35years,Teeterhassetthestandardforqualityinversionequipmentyoucan trust.MyfriendsoveratTeeterhavedecidedtoshowsomelovetoBulletproof listeners.Foralimitedtime,youcangettheTeeterInversionTablewithbonus accessoriesandafreepairofgravityboots,soyoucaninvertathomeortaketheboots withyoutothegym.Togetthisdeal,whichisasavingsofover138bucks,goto GetTeeter.com/bulletproof.You'llalsogetfreeshipping,anda60-daymoneyback guarantee,andfreereturns,sothere'sabsolutelynoriskforyoutotryitout. Remember,youcanonlygettheTeeterwithbonusaccessoriesandafreepairofgravity bootsbygoingtoGetTeeter.com/bulletproof.G-E-TT-E-E-T-E-R.com/bulletproof.Check itout. BulletproofRadio,astationofhighperformance. You'relisteningtoBulletproofRadiowithDaveAsprey.Today'scoolfactofthedayis thatthere'salotoftalkabouthempversusmarijuanatheseday.Actually,Iamgoingto shareacoupleofcoolfactswithyouthatarerelevanttotoday'sshow.Bothcomefrom thesameplant.Botharefromthesamegenuscannabis,andtheyareboththesame speciessativa. Doyouknowthedifferencebetweenthetwo?It'sjustonegeneticswitchthatwasonly discoveredin2011attheUniversityofSaskatchewan.GoCanada.Thebiochemistfound thatgeneticdifferentiationthatallowsmarijuanatohavethepsychoactiveproperties thathempdoesn't.Hempdoesn'tproducetheenzymecalled"TCHA."That'saprecursor toTHC.Ifyoulookatmarijuanaplants,theymakeTCHA,andtheydonotproduce CBDA,whichiscannabidiolicacid,awordthatInevercansayverywell.Thatwhatwe're goingtotalkabouttoday,whichisbasicallyaCBDoil. BeforeIgetintotheshow,whichIdefinitelydidalittleforeshadowingon,youmight havenoticedwe'regoingtobetalkingaboutCBDoil,butwe'regoingtotalkabout anotherkindofoilfirst. Here'sabigannouncementforyoutoday.Well,actually,it'sasmallannouncement,like threeouncessmall.Afterreceivingliterallythousandsofemailsfrompeoplerequesting somethingmoreportablethanour16and30transbottlesofBrainOctane,Bulletproof isfinallyrollingoutatthree-ouncetravelsizebottle.Theyareportable.Theyarespillproof.TheyareTSA-friendly.Theycomeinjustunderthethreepointfour-ounceliquid theymadeforairplanes.That'sreallyimportantforsomeonelikemewhotravelsover 100daysoutoftheyear. Inordertocelebratethekick-offofthenewthree-ouncebottleofBrainOctane,Iam offeringyouachancetotryoutthethree-ouncebottleforfree.Allyouhavetodois pick-upthecostofshipping.Justtexttheword"BPRadio"tothenumber38470onyour mobilephone,andthenrespondwithyouremailaddresstogetaspecialcouponcode forathree-ouncebottleofBrainOctanefreewhenyoupaystandardshippinganywhere intheUS.Again,justtexttheword"BPRadio"tothenumber38470.That'snumber 38470,andreplywhenyougetatextbackaskingforyouremailaddress,soIcanemail youthecodeforafreebottle. Iactuallystartedcarryingsixofthesebottlesinmyquart-sizeziplock,andit'sstillcarry onlegal.Infact,Itookitupto22thousandfeetaltitudeinmyatmosphericpressure. Why?BecauseIcould.Ievenputitontopofmywife'sreallyexpensivepursetoprove thatitwouldwork.YoucanfinditonBulletProof.com. Iftoday'spodcastrocksyourworldasmuchasIhopeitdoes,I'dloveitifyou'dfollow BulletProofRadioiniTunesandleavesomefeedback.Justalittlebitofafive-star feedbacktakesyouaboutthreesecondstodo,andit'sseriouslyhelpspeoplefindthe show.Thanksifyoudecidetodothat. OneofthefirstproblemsIreckonsolvingafterIdevelopedtheBulletProofdietand shedallofmyunwantedfatwasIhadtoshopfornewclothing,everythingfrompants andt-shirts,toshortsanddresssuits.Buyingasuitwasalwayspainfulforme.Finding somethingthat'scomfortable,affordable,andbuiltwithqualitymaterialswasapainful experience. ThensomeoneintroducedmetoIndochino.Indochinoisoneofthelargestmadeto measuremen'swearbrands.Theyaremakingiteasyformentogetagreatfittinghighqualitysuitandshirtatanincredibleprice. Here'showitworks.VisitIndochino.comordropbyanyoftheirnineNorthAmerican showrooms.Pickfromhundredsoffabricsandpatterns.Chooseyourcustomizations fromlapels,topleats,tojacketliningsandmore.Submityourbodymeasurements.Kick back,relax,andgetreadytostepintothebestmoststylishsuityou'veeverworninjust fourweeks. Thisweek,BulletprooflistenerscangetanypremiumIndochinosuitforjust$389at Indochino.comwhenenteringcode"Bulletproof"atcheck-out.That's50%offthe regularpriceforamadetomeasurepremiumsuit,plusshippingisfree.That's Indochino.com,promocode"Bulletproof"foranypremiumsuitforjust389buckswith freeshipping.You'llneverhavetoworryaboutbadlyfittingsuitsorexpensivetripsto thetailoragain.Getreadytolooklikeamillionbucks. BPR-JoelStanley Page 2 of 19 Joel: Dave: Joel: Dave: Joel: Today'sguestisJoelStanley.He'stheCEOofCharlotte'sWeb,oneofthepioneering hempoilextractcompaniesthat'strailblazinginthemedicalcannabisindustry.Joeland hisbrothersJessie,John,Jordan,Jarred,JohnandAustin.WhyAustindoesn'tstartwith a"J,"Idon'tknow,butman,I'mgoingtohavetoaskthis,Joel.They'veearnedthe reputationforbeingthetopcannabisbreedersandcultivators.We'retalkinglikeweeds level,except,well,real. They'vebeenfeaturesonNationalGeographic,Time,CNN,NewYorkTimesandabunch more.Theycreatedsomethingcalled"TheRealmofCaring,"whichisanon-profitthat providescannabiseducation,fundingforstudies,andhelpsfamilieswithaccessto cannabistreatment.WhenIsayithelpsfamilies,Imean,therewereabout15,000what theycall"medicalrefugees"whomovedintheUStogotoColoradoinordertoget accessmostlyfortheirsickchildreninordertogetaccesstoJoel'soilfromCharlotte's Web,whichisprettyamazing. Today,Joelandhisbrothersrungreenhouses,dispensariesandlabsthatproducetheir hempproducts.They'vemadeabigdifferenceforalotofpeople,andthat'swhyI've hadthemon.Joel,welcometotheshow,man. Thankyouforhavingme,Dave.Iappreciateit. Whatdidyouthinkofthatintro.DidInailitordidImisshalfofthecoolstuff? No.Thatwasgreat.Thatwasgreat.Iffact,thatwasflattering.Yourquestionabout AustinbeingtheonlybrotherwithoutaJname,hisfirstnameisactually"J."Period.Not J-A-Y.It'sJ.AustinStanley.There's11ofustotal,sevenboys,fourgirls.Theynamedall theboys.Iguess,atsomepoint,myparentsjustsaid,"What'shisnextname?,"andthey justsaid,"J.Period." Inamedmykidsallstartingwith"As."Kindofasimilarwayofthinking,IrealizethatI onlyneededthreeletterstospellmywife'snameandbothofmykid'snames,because I'macomputerscienceguy,highcompressionratioformyfamily'sname.The14people wholookatcompressionrationsarelaughingrightnow.It'sgoodtoplaywithyour family'sname.Moreimportantly,andmoretothepoint,whatmadeyougetinto medicalcannabisasopposedtojustgettinghigh? Youknow,Iactuallywasn'tabelieveraboutsixmonthsbefore.Thisishardtoadmit. AboutsixmonthsbeforeIgotintotheindustrywithmyyoungerbrothers,myolder brotherhadstartedthefirstdispensarymedicalcannabisdispensaryinthecityof Denver.WhenIheardaboutit,Ijuststartedlaughing.Ijustdidn'tseecannabiswhatI calledatthetime,ofcourse,"marijuana"asbiginmedicine.Ithinkthatitwasan excuse. Bythesametoken,itwasnotinprohibition,andsoIwasn'tagainstit.Ijustdidn'treally understandit.IflewbacktoColorado.Atthattime,IliveinTexas.Ihadtogoseehis dispensary.Asluckwouldhaveit,thefirstthreepeoplethatImetwhowalkedthrough thedooraftermewerecancerpatients,stagethree,stagefourtypecancergoing BPR-JoelStanley Page 3 of 19 Dave: Joel: Dave: Joel: throughsevereroundsofchemotherapy.Igottheirstory,andthatimmediatelychange mymind.I'veneverthoughtofsomethingwhatwecallthe"munchies"asbeing therapeuticwhenit'sextremelytherapeuticwhensomeonecan'teat,can'tholdfood down.Thatwasmyfirstsellingpointonmedicalcannabis. IwentbacktomyjobinTexasandstartedreadingaboutit,startedpumpingthrough PubMed.Ilookedatalloftheseresearchpapers,andIcouldn'tbelievehowmany researchpapershadbeenwrittenonthetopicofcannabis.Attheverybeginning,we foundthisfunnyword"cannabidiol",abbreviated"CBD."That'salotofwhatwe're talkingaboutheretoday. Youhavestudiesshowinganeuroprotectivebenefits,studyshowinganti-inflammatory, studyshowingthatitcouldpotentiallytreattheunderlyingdiseaseofcancer.Thisis extremelypromising,butwhenyoulookintocannabidiol,youseethisisnonpsychoactive,notlikeTHC,whichisthepsychoactivecannabidiolweallassociatedwith gettinghigh.Cannabidiol,CBDdoesalotofthesamethingsthatTHCdoeswithoutthat euphoriceffect. Someofusdon'treallylikesmokinghighTHCcannabis.Ipersonallydon't.Itdoesn'tjive withme.Manypeoplebenefitfromit,butsomeofuswouldliketoenjoythisplant withoutgettingskyhighorparanoidorwhateverhappenstouswhenwesmoke.Some peoplehavefits,somepeopledoesn't.Westartedbreedingforit. Iwentonapodcastonce.Thehostofthepodcastwasstonedoutofhismind.Itwas like,"Here.Havesome."I'mlike,"I'msorry.IwanttobecoherentwhenIoffer somethingtoyouraudiencehere.Ijustcouldn'tdoit."Likeyou,THCisnotmydrug.Like CBDoiliscool,butTHC...I'vealwaysbeensupportingpeoplewhenitworksforthem, butman,Idon'tdowellonhighdosesofthatstuff.Ijustgettired. I'mthesameway.Iactuallytendtofreakoutalittlebit.Therearesomepeoplewhoare sofunctional,andyouarejustlike,"Howareyoudoingthat?"It'swhenpeopleget throughtheirdaywiththat.Imean,whethertheyhavea...Theymayhavean endocannabinoiddeficiencyorsomethinglikethis,anditjustseemstobalancethem. Someofus,Ithinkit'sabout15%ofussofarthathavebeenabletotellthatitdoesn't jivewiththemorprobablybetteroffwithoutthepsychoactivesideofcannabis. Idon'tmeantointerruptyouthere,butIwasjustcomparingwhereIwouldbedisabled ifItookthreeorfourhitsofreallystrongstuff,andthentrytogiveacoherent interview.Ijustwouldramble,butotherpeoplewouldn't.What'sgoingonthere?Digin onthataboutchemicallytotheextendyouknow. Wehavetwospecificreceptorsinsideourbody,maybemore,buttwothatweknowof called"CB1"and"CB2"receptors.Thesearecannabinoidreceptors.Cannabinoidare onlymadebytwothingsontheplanet,that'sourbodies;mammals,andthoseare called"endocannabinoid."Thenthecannabisplantmakesphytocannabinoids.THCisa cannabinoid.CBDisacannabinoid. BPR-JoelStanley Page 4 of 19 Dave: Joel: Dave: Joel: Mostofthecannabinoidarenon-psychoactive.Wecangetthemfromhemp,whichwill gointo.Mentioningheendocannabinoidsystemisveryimportant,becausethisisan infantscientificdiscovery.1994waswhenwefoundoutaboutthesystemthatthis systemisintegraltoeveryothersysteminourbodies.It'skindoftheregulatorofthe regulators. ThoseCB1,CB2receptorsarefoundatalmosteverycellinourbodyprolificthroughout ourcentralnervoussystemthroughoutourbrainstem,andtheninourgut.That's anotherimportantplacewherewefindCB2receptors. CBDandTHCandthenthevariouscannabinoidsdoverydifferentthingsatthese receptors.Whiletherearestillalotofresearchtobedone,unfortunately,the prohibition,alsoaprohibitiveresearch,weatleastunderstandthatCBDisdoing amazingthingsatthesereceptorsitesformanypeople.Imean,asyoumentioned,we haveonetimewaitinglistof15,000peoplewiththousandsandthousandsofpediatric epilepsy,autism.Now,weseealotofParkinson's. Researchhasn'tbeendonetoactuallymakeaclaimonthesethings,buttheanecdotal evidence,andthereportswegeteverydayarejustphenomenal.Westartedtolookat thisandsay,foraguylikemewhodoesn'tenjoyTHC,nowIcanenjoythecannabis plant,thosehealthbenefitswithoutgettinghigh.Westartedtolookatitandjust explorewhatcanthesecompounds,especiallythenon-psychoactiveones,theonesthat arelegal,whatcantheydoforeverydayhealthforpreventativemaintenance,because theyarehelpingsomanypeoplerightnow. BecauseyousellCBDoil,youareusingthecarefuldanceoflanguagewhere...Isit thingslikemaintainproperhealthandalltheother...Idon'tknowifIshouldreallysay this.Idon'tswearthatoften,butIwillsayalltheotherbullshitthatisrequiredwhen yousellsomething,Ihaveasimilarproblemwithcoffee,whereIamnotallowedtosay mostofwhatcoffeedoes,becausetheyIwouldbemakingclaimsthatwouldbe consideredtobepharmaceutical,soI'mlike,"Coffee,it'slikeblackandstuff."I'm allowed... Youknowthedrill. Iknowthedrill.Forpeoplelistening,whenyoucareenoughaboutsomethingto becomeanexpertandthenjuststartmanufacturingit,therearegagorders.I've actuallyhadpeoplesayflatout,youhavelefttherealmoffreespeech.Youarenowin therealmofcontrolledspeech.Thisisfromagovernmentregulator.YouandIareboth inthisinterviewifwetalkaboutourownstufflimitedaboutwhatweareallowedto say.IcansaywhatevertheheckIwantaboutCBDoil,becauseIdon'tsellit. Yousurecan.Yousurecan,butIamtheCEOofCWHempthatmakesthatproduct, Charlotte'sWeb.Ican't.Idopointtomanyofthestoriesthatthereasonwhythiswhole phenomenonhappenedwasbecauseofalittlegirlnamed"Charlotte."Shewasfive yearsoldatthetime.Shewastakingthisproductandnootherdrugsworked.Shehad beenthroughallofthepharmaceuticaloptions,whichbytheway,forherdiseasestate BPR-JoelStanley Page 5 of 19 Dave: Joel: Dave: Joel: afterheragetherewasnotoneFDA-approveddrug,andit'sallexperimental. Backthen,wetookalotofflagforhowcouldyougivesomeprobeofcannabistoakid? It'slike,well,shehadtheapprovalfromneurologistandtwootherdoctors,becauseshe wasend-of-life.Shehadnothingelsetotry.Thatphenomenonmadethisstory. Forawhile,weliveinasystemwhereifsomethingappearstowork,nowithastobea drug.That'sjustinsane,butthat'sthesystemwehave.Theword"drug"inspiresalotof thingsinalotofpeople'smind.Alotofpeoplethinkingjustpsychoactiveorrecreational ordamagingdrugs,harshdrugs. Thetruthiswhatmakesadrugadrugfromaregulatoryperspective,fromtheFDA's perspectiveiswhetherornotyoumakeaspecifichealthclaimaboutit.Thiscouldbe done...IfIholdupanappleandIamtryingtosellapples,andIsaythatthisapplehas vitaminC,andthisvitaminCisgoodforthecommoncold.Ifthat'snotanFDAapproved claimtheycancomeandconfiscatealltheapplesthatI'msellingandsay,"Youwere sellingadrug."That'showitworkshereintheUS. Evenifyouhave50studiesthatsayapplesaregoodforacure,untiltheyapprovethe claimyoustillcan'tdoit.Thesamething.Iamnotallowedtosayhealthysaturatedfats aroundbrainoctane,soIdoubt,eventhoughIwouldarguevery,verywellthatit's healthygiventhathealthyisabigword.Theyapplyhealthytocornflakesandlikelow fatweirdcrap.Thebottomlineisifit'snotlikerubberstampedbyaregulatory...I'm notallowedtosayit.IjustwantpeoplelisteningtoknowthatwhenIaskyouquestions whenwe'reinterviewinglikethatthatyouaresubjecttowhatIwouldcallgagorders. Allpeoplewhomakefoodsandsupplementsarelimitedinwhatwecansayabout them.Ithinklistenersoftentimesdon'tunderstandthat. Thatishelpfultothemandtome,sothankyou.Thankyou. SomeofthethingsthatIamawarethatCBDoilhasbeenusedforwouldbethingslike epilepsy.Mymotherhashadepilepsyformyentirelife.Shehadsurgerythathelps prettydramatically,becausethedosesofdrugsshewastakingweregettingtobetoxic tothepointtheywerejustbuildingupinherbodyafter20somethingyearsorusingit. I'mdefinitelyfamiliarwiththeeffectsofepilepsyonthings.Itworksreallywellforthat. Diabetes,rheumatoidarthritis,alltheseotherimmuneconditionsthatIcertainlyhave autoimmunity.IhadarthritisonmykneessinceIwas14,cancer,antibioticresistant infections,alcoholismeven.IhadPTSD,neurologicaldisorders.That'saprettylonglist ofthings.Therearen'tstudies,likebigstudiesinallthosethings.There'slotsofother evidencethough. WhenyoulookatthefactthattheUSgovernmentnationalinstituteofhealthin2003, divisionoftheUSgovernmentactuallyfiledapatentonbehalfofwethepeople,Iguess, oncannabinoidsasneuroprotectantsandantioxidants.Weconsiderjustawordlike "neuroprotectant."Now,alotofthediseasestageyouimaged,whateverthat's somethingoccurringthatisneuroprotectiveandtheUSgovernmentadmitstoit,now youareontosomethingforthoseneurologicaldisordersaswell.Itjustmakessense.We BPR-JoelStanley Page 6 of 19 Dave: Joel: Dave: Joel: Dave: Joel: Dave: Joel: knowtheyareprotective.WeknowthatwehavetheCB1,CB2receptorsforourcentral nervoussystem.Ofcourse,itisgoingtoimpactsomeofthosediseasestatespotentially. AsImentioned,prohibitiondidn'tjustprohibitusfrompossessingallthoseyears,italso prohibitedresearch. Yeah.We'redealingwiththatrightnow.There'speoplecallingforlet'ssaybanningof researchoncertaintopicsthataretabooandIfindthattobeinsane.Youneverban researchonanything,becauseunderstandinglet'syouknowhowdangerousoruseful somethingis.Whenyoustoplookingatit,it'slikewillfullyputtingonblinders.Someof theskepticsouttheredothat.LikeyoucannotresearchX,becauseIdon'tbelievethat there'sawayitcanwork.Really?Inthatcase,maybeyoushouldn'tresearch,and someoneelsemightknowmorethanyoushouldresearchit.Justathought. That'swhyallofthegreatresearchgoingonaroundtheworldonthatnotjustcannabis, butpsychedelicsingeneralisjustbeenprohibited,justblindlyblanketprohibited.That's whatIamsayingwaytoapproachanything.Untilweliftthevaleandstarapproaching thetopicofdrugsandpsychotropicdrugswithinformationandeducationinsteadofjust asblindfoldedfear,we'renotgoingtogetanywhere.We'regoingtocontinuetoseea rushofteamswantingtousewhateverweprohibit.Youlookthroughouthistoryand cannabisitselfhasbeenusedbyalmosteverycivilization,sometimesinmajorways,and youcan'tfindarecordofteamsinmassnumberstryingtogettheirhandsonituntilwe said,"Oh,youcan'thaveit."It'sjustasillywaytoapproachit. Youjustgavemeagreatidea.Whatifwebannedhigh-intensityintervaltraining?Like wouldteenagersevergooutandstartexercising?Iwonder. Weshouldmaybebanthat.Yeah.Weshouldmaybebanthat.Weshouldbanbuilding fruits.andcondoneplayingNintendo.Maybethatwillgettheirbloodsatisfied. That'sawesome.Now,there'ssomeotherstuff.I'vespentalotoftime.Ihaveanew bookthat'scomingoutinAprilaboutmitochondria.Ispendbasicallythelastyearreally digginginmitochondria,eventhoughIhavebeenmodifyingmineforabout15years. WhenyoulookatAlzheimer's,Parkinson'sandprettymucheveryneurodegenerative disease,ALS,itallcomesdowntotheseenergyformingorganellesthatareinsidethe neurons.Theygetweakandyougetthesethings.CBDhasreallystrongantioxidantand neuroprotectorproperties.Doyouknow,isitaffectyourmitochondriaorisitdoing somethingtotheneuron?Doyouknowhowit'sworkingthere? Iwouldlovetobeabletoexplainthattoyou,butIknowafewpeoplewhocould,but theyarenothererightnow. Therearenothere. Ionlygettoodeepinotherways.I'velearnedalotofmedicalandtechnology.I'vemet withsomeoftheworld'stopneurologistsimplybecauseofCharlotte'slab,andIlovefor themtospeak,butIamjustnotversedenoughtoaddressthat. BPR-JoelStanley Page 7 of 19 Dave: Joel: Dave: Allright.Idon'twanttogotoodeepfortheaudienceeither.Iamjustalwaysso interestedwhenyouseethesecommonelementswhereyouseesomethingthat'sas broadlyeffectiveasCBD.Italwaysmakesmewonderlikeisithappeningataverylow levelinthecell.What'sanormal...Firstyoulistentothis.Ihaveapsoriasis,let'ssay,or Ihavesomeotherimmunestuff,Hashimoto's,thyroiditisorsomething.Iftheysaid, "Youknow,IthinkIwanttotryCBDoil."Shouldtheydototheirdoctor?Shouldthey startexperimenting?Shouldtheysparkupabowl?What'stherightpathwayforthem? TherightpathwayforthemistostartwithCBD.Anyonewhoisinterestedintrying cannabis,becausetheyhasanti-inflammatory,anyofthem,neurodegenerative disordersorjustpeoplethatwanttotakeitforpreventativemaintenance,becausethey areafraidofneurologicaldisorders.CBDistheveryplacetostart,becauseweactually canderiveitfromhemp.Hempisalegalproduct.TheUSinfactimportsmorehemp thananyothercountryintheworld.Theyonlyhave5%oftheworld'spopulation.It's beenlegalfordecades,butjustlegaltothecultivatedintheUSasof2014. Thatwasevenprohibitedforawhile.TheycanseekoutCBDfromhempsourcesno matterwhatstatetheyliveinnow.OurproductsCharlotte'sWeb.Theycangoto CWHemp.com,C-W-H-E-M-Pdotcom.Ialsohavethenonprofitorganization,"Thereal OfCaring."Asyouknow,ifsomeonecallsmycustomerserviceteamandsays,"Hey.I've gotParkinson's,orALS.HowdoIdosethis?,"weabsolutelycannothandlethat question.We'renotallowedto.Weformed"TheRealmOfCaring,"whichisan organizationthatcollectsmostofthevolunteersandmostofthecallcenterstaffthere areactuallyfamiliesthathavealreadybeenthroughthis,alreadylearnedhowtodose cannabisappropriatelyforXYZcondition. Weconnectthenewclientwitholdclients.Theycandiscussthatbehindtheirown closeddoors.Wehavenursesthere,sotheycandiscusswiththeirdoctors.Thisisavery viabletool,andIwouldrecommendthatanyonewithaninflammatorydisorderor whetherneurologicaldisordertotrycannabisasasafeoption.Thecannabishasnever killedanyone.We'retalkingaboutasafetyprofileonCBD.That'smuchlikevitaminC. It'ssaferthancommonhouseholdsugar.It'sworththetry. Thenbeyondthat,beyondsomeonethatsaysokayI'vegotthisinflammatorydisorder, justforgeneralhealth,ImeanItoldyouearlierthatI'vebeendopingBulletproofcoffee foroverayearnow.Iaddmyownproducttoit.Myproducttoyourproductbecause that'smydailydoseofCBD,rightawaytakeitwhileIhave...Notregularinflammation, butitseemstokeeptheairwayfromcertainproblemsassociated.Idon'twanttoget theweedsthere.Ineedtobereallycarefulhere.Itakeitbecauseit'spreventive maintenance,andIthinkthattheaveragepersonespeciallyoncewestarttounderstand alittlebitmoreaboutwhatthisisdoingatthatcellularlevel,oncewegettheresearch,I thinkwearedefinitelygoingtoseethatthisshouldbeapartofeveryone'sdietjustlike vitaminC,justlikeyourBvitamins,justlikeyouromegas.Wehaveendocannabinoids system.Whywouldn'twehavecannabinoidstosupplementdaily?It'sjustbeenlocked outbyprohibition. That'sright.Iamplanningtoliveto180orlonger.That'sarealnumber,andsome BPR-JoelStanley Page 8 of 19 Joel: Dave: Joel: peoplearelike,there'snoevidencethat...Yes,there'snoevidenceanyofusisgoingto liveformorethanonemoreminute.That'sokay,butIamdoingeverythingIcanto minimizeallofthethousandsofthingsthatjustwhittleawayatyourabilitytomaintain andrepairyourownsystem,and180seemsprettyreasonablegiventherateofchange attack.It'slikeit'sthatpreventativemaintenancereallymatters,anddoingsomething foryournervoussystemactuallydoalotofthingsforyou,butdoinganotherthingfor thenervoussystemandworkingwiththeendocannabinoidsystemseemslikeapretty goodcandidateforthat.Doyouhaveanystudiesonageing? Wedon't.Wedon't,butweareengagingcertainuniversitiestodothesestudiesand findwhatistherightcannabinoidcombination,whatistherightplantforpreventative maintenanceforageingespeciallyneurologically.Again,itgoesbacktoprohibition.Iam suretherewillbeaplethoraofthosestudiesoutthereifwehadn'tprohibited researchersfromactuallyhandlingthatsubstanceforsolong. It'sfunnywhenwecompareyourbiggestcompetitor,whichshouldbebigtobacco.They arefreakedoutaboutallthesenewthingpotgars.Theamountofresearchavailableon nicotineandtobaccoisunbelievable.Ofcourse,theysuppressthosestuffandsaidit causedcancer,becauseitwasbadforbusiness.I'mreallyhopingthatiftheydofind somedownsidesformarijuanathatwedon'tmakethatmistakeagain.Ithinkthe internetmakesithardertohideresearchfor50yearsliketheydidinbigtobacco. Ihavefoundthatlowdosenicotinewhentheirstudiesgoingback10,15years,it increasesmitochondriafunction.Entirelyseparatefromsmoking,Ithinkalotofthe problemswithpotwherepeopleburningstuffandbreathingit,whichisclearlyageing, notanti-aging.Thenyouarelike,okay,amIgettingmoldypot,likequalitycontrol wasn'tthere.Allthesethingswentintopeoplesay,oh,liketheprosandtheconswere sointermixitwashardtosortthemout,butwithwhatyouaredoingyouhavea scientificallycontrolledproduct.You'retakingouttheTHCvariable,whichactuallycould beanti-inflammatoryinitofitselfinsomepeople.Youarealsoallowingustouse somethingthatnowwecandoandforproperresearchon,becauseitdoesn'tfallinto thiscrazyprohibitionareathing,butifwehaven'tprohibitedit,wehavemuchmore datathanwedid. You'retalkingaboutaddingittoyourBulletproofcoffee.Awhileback,Itriedsomekind of...IdidapodcastawhilebackwetalkabouthippyspeedballaddingaCBDoiltoa bulletproofcoffeeanditwasprettyfunny.TheproblemthoughIhadisthatIhadsome CBDoilbutterblendthatsomeonemadeformethatwasnon-THC.ItookitandIswear Ithoughtmyskinwasgoingtofalloff.LikeIgotextremelydryskin,likerashes.Iwaslike thisisnotgood.Ithinkitwasactuallythatbrandofstuff.Isitpossiblethat... IsitpossiblethatpeoplewouldhaveabadreactiontoCBDitself.Iwouldsay,ofcourse. Imean,that'spossibletobeallergictoanyplant.Ofcourse,it'spossiblesomeonecould beallergictotheplantsweusefortheCharlotte'swebproduct.That'sreallypossible. Wehaven'treallyseenthatyet.Now,Imean,we'vebeenthroughthousandsoffolks wherewegottenthatreport,but... BPR-JoelStanley Page 9 of 19 Dave: Joel: Dave: Joel: Dave: Joel: Dave: Joel: Thiswasn'tCharlotte'sweb.Thiswasanotherbrand.Ithoughtitmighthavebeenlikea purityissuewithit.I'veusedCBDoilinotherformswithoutproblems.Icansmokepot. I'mahittertoo.I'mfine,butyougivememorethanthat... Youarenotallergictocannabis. No,I'mnot. Sorry. Likeasolventissueorsomething. Idon'tliketothrilltheindustryherewithabuzz,butinalotofways,it'salreadyunder there. It'sagreatone. Nothingintheindustrythatwasbornoutofclosetsandbasementsandproductsmade indingygaragesthatsameplacespeopleworkingontheircars.Alotofthatisn't becausethosefolksmakingitwantedittobethatway,butitwasbecauseitwas prohibited.Nowthatitisnotprohibitedeventhemanningofthestatesifyouwantto doittherightway,youdon'twanttohaveaccesstoconventionallending.Banksaren't goingtolendtoyoutostartabusinesstodothis. Wecanberealhardontheindustryforitsqualitycontrol,butatthesametimeit doesn'thavethesametoolsofaccessforconventionalbusinesses,andsoifyouallyou controlhasbeenverylow.That'sonethingwe[inaudible00:31:59]ourselveson.Ican't tellyouhowfreakyitwastohavethisfive-year-oldyearsago,Charlottewhowas medicallyfragile,end-of-life.It'sontheresuscitateforher,andwe'regoingtocreatea productnowforhertotryoutofcannabiswithallthestigmasassociatedwithcannabis. Iwasshaking.Iwasliterallyshaking.Wetoolallthecontrolseriously.Wehadwith predominantlycancerpatientsbeforethose.Wetookitveryseriously. Thattookmythinkingtothenextlevel.Imean,wejusttookittoextremelevelsof testingandjustoverallcleanliness,documentationhowyoumaketheseproducts.Back then,Iwasmakingtheseproductsformaybe40or50peoplewhoeverhadjustheard aboutCharlotte'sstorythroughFacebookorwhatever.Youcanhavequalitycontrol.It's kindoflikeifyoucanmakeabatchofbrowniesforhouseguestorpastorwhatever,it's goingtobeconsumedrightthenandthere. Whenyou'regoingtomakeaproductforthousandsandthousandsofconsumersand youhavetounderstandhowdoIpackagethis,whatcanhappenintheprocesstomake thispotentiallyhavesomethingthatcangrowinsideofthatsometypeof biocontaminant,andthenhowlongisitgoingtostore.Thosestudiestaketime.When you'redevelopinganewproductespeciallyyouneedtotakeeveryinstitutiontomake surethattherearenotoxinsinthatproducts,andthisfromthepesticidesatthefarm. BPR-JoelStanley Page 10 of 19 Dave: Joel: Evenhavingmetals.Hempisagreatlandreclamationcrop,buttheproblemisImean weallconsumesomesmallamountofledeveryday,everytimeyouhadanapple you'vegotsometraceacceptableamountofled.Itmightevenbeimportant.Wedon't reallyknow.Youmightevenneedthatsmalllevel.Whenyouhavealandreclamation crop,likehemp,anditpullsupledintoitself,likemostplantsdo,andthenyoucan concentratethatplant.Now,youarealsoconcentratingthosepotentialcontaminants. Itmightnothavebeenharmful.Theactualplantitselfatplantlevels,butnowyou've concentratedit.Idon'tknowexactlywhathappenedwithyou,butIcanassumethatit's likelyanissueofqualitycontrolandsometypeofcontaminantthatthemanufacturer didn'ttakecareof. ThatwasmyguessaswelljustbecauseIknowotherstuffworks.Thatwasabitspooky andworthpayingattentionto.Iknowmanyotherpeoplewho'vehadreallystrong benefits,soIwilltrysomeofyoursnowthatwe'vetalkedalittlebitaboutthequality controlaspectsofit.Peoplelisteningtoourinterviewprobablyhaven'tthoughtabout whatyoujustsaid,butthescaleoferror,you'rescrapingyourkitchen,whatever,but youscrapandyou'remakingsomethingforhundredsofthousandsofpeople,youcould makethemsick.Likeyoumustnotdothat.Also,it'sgoingtobestoredforawhile,so caresifyourbrownieshadalittlesomethinginthem,becauseyouateit. Idealwiththat.Wemakethebulletproofcollagenbars.Gettingthoserighttooktwo yearstogetoutofthedoorwheretheyhavethebrainoctane,andtheyholdtogether. Theydon'thavethemicrobialstuff.Wejustlaunchourkey,whichyoucanusewith CBDF.Alotofpeopleactuallyuse[key00:35:31]andCBDtogether.Wemakeitfrom 100%grass-fedbutter,butourfirstbatch,ourfirstcommercialbatchof8,000bottlesor 8,000jarsofitwasruined,becauseonepersondidn'tchangeafiltertheywere supposedtochange. Likeyou,I'malmostcertainyoudothis,wetesteverythingreligiously.Wetestbefore. Wetestduring.Wetestafter,andwetestitafterlikewhat'sgoingonhere.Alittlebitof proteinmadeitthroughthatshitanditmadeitthrough.Itdidn'tmeetthestandards, anditwouldhavegrownstuffeventually.Yeah.Thatwasjustawasteofbutter,butit wasbetterthansendingittopeople,becausethatwouldhavebeenevenworse.That thingisentirelyinvisibletotheworld,butit'snotpresentwhenyouaredoinglikeareal earlystagesupplementyou'redoing,someonemakingstuffintheirgarage,whichyou can'tdo.Theyarejustlikeprettyregulatory,sothequalitycontrolthingsareinplace. It'sactuallyalittlebitfrustratingtodealwiththat.Iimagineyouhavethatproblem,too, right? Wehadsimilarstory,thisonehadnothingtodowithourmanufacturingprocesses internally,butwhathadhappenedwasIwalkeduptoourlabonedayandIwentback, andthey'redumpingfullbottlesofCharlotte'sweb.Actually,thiscomingfromaguy witha15,000personwaitinglistthatwasheavythatwasscary.Everymilligramwasso precious.Now,we'vegotplenty.We'veenteredthewaitinglist,butstillthey're doublingthesefullbottlesofCharlotte'sWebandintothoseabsorbentmaterial.They arebasicallyrejectingabatch.Thishappenedafewtimesforvariousreasons,whichis reallyabatchofbar.Whenacompanyfindssomethinginsays,"We'renotgoingtotake BPR-JoelStanley Page 11 of 19 Dave: Joel: thisbatch,becauseitdoesn'tmeetourqualityspecs."Iaskedwhathappened,andthey said,well,wewentthroughtheentireprocess,andwetesteverythingforaflatoxins, molds,solventsthroughthewholeprocess.Itgetstestedseveraltimeswhileit'sanoil afterit'sinfused,beforeit'sgtbottled,andthenitgoesasfinalbottles,randombottles gotothelabtotestforthesethings. Whenwehavethefinalpackaging,wehaveaflatoxinspresent.Whatwerethelevels? MyQCguy,awesomeguy,says,"Well,theywereacceptableforcertainfoods,alotof foods,buttheyweren'tacceptablewithinourspec."Isaid,"Allright.That'sawesome. Wehavehigherspec.Great."Howdidthathappen?Acoupleofweekslater,hegets backtomeandsays,"Younowwhat?Itwasinthelittledroppersfromthebottles,from hemanufacturer,thosefoodssupposedtobefood-gradedropperbottleshaveresidual levelsofanaflatoxin.Itwasn'tevenanythingwedidwrong.Itwasinsidethosejars, thosecells,thoselittleglassdroppers,sowerejectedthatwholebatch.Welookthatas acompanyandtosay,thathurts. Yougettothefinishlinewithsomething,andyoujustseesomeonedumpit.Sometimes hurtsathousandsofdollarsretainintoa[inaudible00:38:37]material.Thatcanfreak youout,butit'stherightthingtodo,andinanycompanythatismakingproducts, dietarysupplements,food,drugonthisscale,you'rejustgoingtorunintoit,because therearevariablesthatarenotalwayswithinourcontrol,andyousetthosemeasures tomakesureyoucatchthem. It'sinterestingyoubroughtupaflatoxin.Thatisthesinglemostcancer-causing substanceknowntoman.Hereitisyouhaveaproductthatotherpeoplewithoutyour knowledgeorpermissionmightbeusingfortheircancer.Youwouldneverdothat.I've runintothat,too.Iwantedtolaunchamockupproductbecausetherearesevenkinds ofMaca.Macaisusefulfortestosteroneinmen,it'susefulforhormonestuffinwomen aswell,dependingonwhatspeciesyouuse.Iwasgettingthesesamplesbackthathad like13partsperbillionofaflatoxin,likeveryhigh-endmanufacturers,becauseit'sa starchproductthat'sdriedinajungle.Youmightimaginemolewillgrow.Finally,Ijust gaveup.I'mlike,I'mnotgoingtodothis,becauseIdon'tthinkIcanreliablymakea microtoxinfreeversionofthis.Maybesomeonedoes.Thereareseveralgoodbrandsof itoutthere,buttheselittlethingsI'mrequiredtotestfortheminalotofproducts,but ifyoucare,youdoitanyway. That'sright.Wehavea...Withinthedietarysupplementvitaminworld,whichisreally whereCharlotte'sWebfits,wehavewhat'scalled"goodmanufacturingpractice"that wasdictatedbytheFDA.Wewentthroughathird-partyCGMPaudit,passwithflying colors.Iwasveryhappyaboutthat.Really,what'smorespecialaboutwhatcompanies likeusdoisthatwealsoadheretothestandardsoftheAmericanNobleProducts Association,whichdivedeeperintotopicslikeaflatoxins.Ourregulatorysystemthatis okaytomakesurethemanufactureshavesomequalitycontrol.Youhavesomeother industrygroupsthathavereallysetthebar,andtheyhavesetthebarattherightplace. Whenpeoplearelookingforproductslikethisoranydietarysupplement,lookfor organizationslikeAHPA,AmericanHerbalProductsAssociation. BPR-JoelStanley Page 12 of 19 Dave: You'llseethatcompaniesthatcomplywiththat,youcanrelyonthoseproductsevery time.Theyaregoingtobeconsistent.Theyarealsogoingtobethesame.Imean,that's anothermajorproblemwehaveinourindustry.It'swhenourstoryhitsCNN,weknew thattherewereveryfewmilligramsofCBDexistinginthewholeworld,andthatwe didn'thaveenoughforourwaitinglist,andwehadmorethananyoneintheworldmost likelyatthatpointintime,becausepeopleintheindustrycouldn'tevenpronouncethe word"cannabinoid"backthem. Suddenly,nowthatit'sonCNNyoustarttoseeonAmazon.comalltheseproductsthat arepoppingup.Peoplegetreallyexcited.Theygettheirhopesup,becausetheyareon thiswaitinglistforCharlotte'sWeb.Theyordertheseproducts.Nothinghappens,and theyarelike,"CBDisBS."Theysentustheproduct.Wetestthem.There'snothinginit. 10timesoutof10backthen,therewasnothinginit.That'sablackmarketinour industry,butdietarysupplementshavethatsameproblem.Consumersneedtojustbe awareofthattherearepeopleouttherethatwilltakeadvantageofyouwithindietary supplements,withinfoodproductsingeneral,vitamins.Lookforthesealsofapproval fromtrustedorganizations. Yeah.It'sinteresting.Someofthemorepowerfulthingsyoucangetlikeanirasetam, oneofthesmartdrugs.I'mafanofthisstuff.Iwouldlovetomakeanirasetamfor people.IthinkIknowthegoodsuppliersandallthat,butit'snotprohibited,butit'snot allowedbytheregulatorypeople.I'vebeenusingthisstuffeverydayformorethan10 years,becauseitincreasesyourblood,itgetsthingsinandoutofyourmemory.I'll probablylivelongerasaresultofusingit.Youhavetogoandjustbuyitformerlyon Amazon,andthenlastyear,onedayAmazonjustdecidedwewon'tsellanyofthese anymore.Allofthevariouslikesmallgaragebrandsofanirasetamjustdisappearedand it'sgottenhardertofind. Amazonhastheabilitytotakethesedown,buttheyusuallydon't.Iftheydo,itcould justbeabroadspectrume,andallofasuddenit'sgone.Peopleoftentimeswhenthere's anemergingtechnologylikeCBDwasafewyearsagowhenyoupioneeredit,itwas hardforpeopletoget.TheyhadtocometoColorado,andthenyougetwhereyoucan shipit,butthenthere'sinterstatecommerceregulatorythings.Allofthatisinvisibleto people. Like,whydon'ttheyjustsendmeCBDoil?That'swideandwherearethere chloroforms?Well,becauseyoucouldn'tgetdistribution,andbecausepeoplewere opportunistic.Theysomethingandsaid,We'llcopythat.Wedon'tknowifwearedoing itright.Yougetthesecopycatbrands,andtheseflybynightoperationsthatdon'tgrow withoutthequalitycontrol,butthatseemslikemostinnovationhappensthere,justlike yoursdid,butyoukeptatit,andnowyouarebeyondtheearlystagewherepeopleare comingtoyoubecausetheyaregoingtodieiftheydon't.Now,youstillhavethose samepeoplewhocanusetheirproductiftheychooseto,butyouhavetheabilityto scaleit.Howdidyoudothat?Thatisreallyunusual.Iknow,becauseIdiditwithwhatI do,butalmostnoonelistening.Tellmethestoryofhowyouwentfromdoingitliterally likeinasmallfacilityforend-of-lifepeople.Howdidyougofromthesewhereyouare now?Givemethestory. BPR-JoelStanley Page 13 of 19 Joel: Youknow,whenwemetCharlotte,hermother,Page,soughtusoutandsaid,"Ihear thatyouguyshavebeenbreathingthisCBD.Ithinkitmightbesomethingthatcould helpmydaughter.Shehadbeenpouringthrougharesearch,andoddlyenoughthere's adecentamountofresearchoutthereforsomethingthatisprohibited."Shefoundit, andshewouldhaveknownaboutCBD.Shehadsearched,scourtheindustry,foundus. Atthattime,wehadonlyeightplantsofthegeneticsthatgointotheCharlotte'sWeb product.Wehad,atthatmomentintime,we'vejustcalledit"hippy'sdisappointment." We'reveryproudofit.Wethoughtitwasgoingtobegreatforpeoplelikemewho didn'twanttogethigh,butstillwantedthehealthbenefits,butlotsofthecancerfolks whodidn'twanttogetskyhigh.Wetookinhisdisappointment.Itwaseightplants.We renamedourentirebreedingprojectafterCharlotte'sWeb,butwewerestuckwithin medicalmarijuanaregulationshereinCorolado. Infact,youcouldn'tgrowhempdomestically.Thisis2012.Underthoseregulations, veryexpensive.Youhavetohaveacamerafromeveryangle,allthesecurity.Youhave RFIDtagsoneveryplant,very...Yes,becauseitissuchadangerousplant.Very expensivetoscale,anditwasheavy,anddoesthiswaitinglistjustgrewandgrewand upto15,000people.Wedideverythingwecouldforpeople.Wehadabonefireswith thiswholecommunity,mostlyofpediatricepilepsy,butalotofautism,too,developed inmyowntownofColoradoSprings.There'sjustwholecommunityofpeople.Manyof themstilllivethereeventhoughtheycangohome.Theystilllivetherejustbecauseof thecommunitythathappenedoutoftheCharlotte'sWebstory,butitwasreallyheavy. Wecouldn'tscaleundermedicalmarijuanaprogram.Fortunately,in2013when Coloradoironicallylegalizerecreationalcampus,inthatsamepieceoflegislation,they alsolegalizethecultivationofindustrialhemp. Shortlyafter,in2014,theFederalGovernmentallowedtheprovisionthatallowforthe firsttimeinmanydecadesthecultivationofindustrialhempthroughthestate departmentsofagriculture.Everythingfellintoplace.Thoseplantsgenetics,theoriginal hempisdisappointment.NowgoingintotheproductCharlotte'sWeb.ThoseoriginalA plantsreallyfitwithinwhatweknowashemp.ThankGodforindustrialhemp regulations,orelsewe'dstillhaveawaitinglist.Wewouldneverbeenabletoscalethe waywedid.Wewentoutfromgreenhouses,RFIDtagsoneveryplanttoagricultural centerpivot,irrigation,stillorganicpractices,allofthese,butwewereabletogofroma fewhundredsplantstoacoupleofhundredthousandplantsonacres.Ourfirstharvest infall2014whileweweredoingthatwewerebuildingthislaboratory. Fortunately,ourstoryhadreachedsomefolksthatwerewillingtoinvestinthis.Atthat time,thatotherCDBproductswereoutthere.AsImentioned,mostofthemwithout anyCBDinthem.ThepricepermilligramofCBDatthattimewas50centspermilligram, averageoutthereintheindustry.Ourswasfive.Itisstillfivecentspermilligramfor anyonewhosignsupwiththeRealmofCaring.Thatmeansthattheyareseriousabout it. Theymightreallyneedit.Butwewereabletogointothishempagriculturaleconomy hasscale,whichfivecentsactuallymadesense.Theyusedtobeacostofgood.Now,it BPR-JoelStanley Page 14 of 19 Dave: Joel: Dave: Joel: Dave: Joel: Dave: Joel: Dave: actuallymakessenseforusasacompany.Wehadinvestors.WesetthelabinBoulder Coloradoinwhichwehadaccesstoallofthesegreatminds,analyticalchemistcoming outoftheUniversityofColorado,andjustmanystrokesofluck,alotofhardwork.We cameto,whatIbelieveisthebestcannabislaboratoryintheworldrightnowthatitall cametogetheroveracoupleofyears,andnowwe'reabletodowhatwedo.Highlevel qualitycontrol,andwedon'thaveawaitinglist. Congratulations.That'safantasticstory.IdidabunchofresearchonCBDreceptorsa whilebackonapieceonthebulletproofblog.Itlookslikethere'ssomeevidencefor vapingCBD.Idon'tknowifyoucantalkaboutthatifvapingmaybesomelikedrug deliverytechnologyorsomethingifyoucantalkaboutitjusttellme. Idon'tgetit. IsthereamerittovapingCBDoilsversusswallowingthem? Ibelievethatthereisandthereisn't.Itdependsonwhatyousaw.Typically,thenyou getaCDBoilforvape,it'sbeenmorefractionated.Thishasbeenthroughaprocess called"winterization"wherethefatsandwaxesandmanyoftheturbines,allother plantphytochemicalsthatactuallydoworkwithCBD,manyofthosearegone.Ifyou needCBDandyouneedCBDquickly,andalotofpeoplethatreportvaping.Infact,Iask peoplewithcertainthingsthatpeoplethathappenedtogetaaurabeforetheyhave oneofthosenastythings... Wellsaid.Lookatthat. Whatafunnythingwehavetodohere.Thereportsareamazing.Iwouldhighly recommenditforpeoplethatneedquickdelivery,becauseinhalationtherapy,wewill callit,getsthingsrightintothebloodstreamquickly.Whereasifyoutakethingsasa supplementunderyourtongueorasapill,swallowit,youaregoingthroughit[] entirelydifferentsystemthat'sgoingtochangethebioavailabilityofeverycompoundin thatplantextract.Bothwaysaregood.Iwouldn'tsayoneovertheother.Itdependson youasaperson,yourbiochemistry,andwhatyou'reusingitfor. Istheresomesortofasystemyoucouldgetwhereyoucouldtakeyouroil,putitina deviceandvapeit?Orisitnotset-upthatway? Weactually...Wehadvapepensoutthere,atestrunforalittlewhile,becausewedo believeinit,asIjustsaid.We'dpullthemrecently,becausewearebasically recalibrating.Wethinkwecandoitbetter.WefiguredoutsomethingsthroughRND, thoughtgreatscientistupinBoulder.We'regoingtorelaunchthatonebothvapeoils thatyoucanputinyourownvapepen,butalsopre-packedvapepenswithCharlotte's Web. Yousaidsomethingelse,too,aboutyourcostofgoods.Oneofthebenefitsofvapingis itrequireslessoftherawmaterialtogettheactiveamountin,butyoucanjusttakeit orallyifit'saffordable,andyou'vegotbecauseyouchangedhowyougrowit,because BPR-JoelStanley Page 15 of 19 Joel: Dave: Joel: Dave: there'ssomeregulatorychangesyou'vegotthecostdown.Itmightbejustmore convenienttopopacapsuleandbedonewithit,unlessyouhaveanurgentneed, becauseyouarestartingtoCRS,andbecauseyouhaveamassiveheadacheorsome otherrapidonsetneurologicalthing.There'sabunchofthosewherepeoplearelike,I wasfeelinggoodfiveminutesthoughIcanfeelsomethingisabouttohappen.Ifthere's arapidinterventionthere,itreallymatters. Itdoes.Thisgoesrighttotheissueaswell.TheCharlotte'sWebwhenItakethemost popularproductatheeverydayevents,andIputitonmytongueorjustswallowit,I amgettingarealwholepunchfromit.AsImentioned,thesecannabinoidsarenotthe onlythingthatworkattheCB1,CB2receptorsites.Theyactdifferentlywhenthere'sa presenceofsimpleplant[]likebeta[],orkinane.Thesearefoundinregularfruitsand vegetables,buttheyarealsofoundwithinCannabis.Itactsdifferentlyatthosereceptor siteswhenothercannabinoidsandotherplantcompoundarepresent,andweyouvape youjustdon'tgetthesamething.Itjustreallydependsonwhatyou'reusingforand whoyouareonyourwonbiochemistry. That'salsowhythe[]geneticsmatter.Thefirstlevelofqualitycontrolthateveryonein cannabis[]lookat,whetheryou'reinCBDorCHCandinmedicalmarijuanafriendly state.Whenyouaremakingaproductthatworksforsomeone,don'tchangeit.Don't changeit.Don'tchangethoseplantgenetics.Imean,peoplejustbuyrandommaterial. Drugintoanoil.Putitintoacarrier,andthen[]withthesamelabel. ThisshouldapplyforAcaciaandeverybotanicalthereisoutthere.Usethosesame genetics,becausejustasyouandIaredifferent,Dave,theseplantsvaryintheir individualfingerprint,theirindividualprofile. It'skindofshocking,butcoffeeisthesameway.Likeifyoubuyitfromabulkbrokerlike 99.9%ofthecoffeeworld,yeah,Iwentthere.Tasteitaboutjustwait...Thegeneticsof theplant,everythingabouttheprocessmatters.You'reright.It'sadifferentview.You arelookingatthesystemofitstartingatthegeneticsandcultivationalltheway throughtothedeliverysystem. Yeah.There'sa[]reasonwhyabotanicalmedicinehasbeenlaughedatforsomany yearsbythemedicalcommunity,whichisactuallychanging.Ithinkcannabisisactually changingthemedicalcommunity'smind,pushingthatpendulumbackovertowards plant-basedmedicine.Whenyoulookatit,becausewenowunderstandthatevery plant,everygenetic,everyphenotypeinanyoneofthesebotanicalmedicinesis potentiallyspecialandgoingtoworkforacertainsubsetorpeople,now,weunderstand howtostandardizethisalittlebitbetter,butthelackofstandardizationshasjust createdabadrepforplantmedicineingeneral. Anotherguessontheshow,aguywho'sbecomeafriend,isAlbertoViodo.He'sa culturalanthropologistandatrainedshaman.Hewentdownabout30yearsagotothe junglestofindmedicalplantsfordrugcompaniesandcamebacktrainedasashaman intothatmeddoingthat.Forsimilarreasonswhereifyoutaketheonecompoundout, youmisstheco-factorsthatsignalotherpartsofthebody. BPR-JoelStanley Page 16 of 19 Joel: Dave: Wehavethis,Iwillcallitahubrisandyou'resaying.We'regoingtodothis.We'regonna findthedrugthat'sintheplant.Whatiftheplantwasthedrug,anditturnsoutthatthis onepartoftheplantbyitselfhasastrongeffect,buttheothersupportingco-factors actuallymakeitworkbetterorhavelessside-effects,butjustthewayweset-upour drugsystem,wesortofrejectedthat.Ithinktheconsciousnessischangingthatpeople wouldratherhaveateaoranherbalextractthanadrugmadefromthesameherb.You arefollowthosefootstepsayinghavethewholeoilversusevenjustvapingit,because vapingityougetlessofitevenifit'syoufaster. Yeah.Thatsinglecompoundsapproachthatwehadtakentothepharmaceuticalsand medicineingeneral,I'mnotgoingtosaythatthat'sbadscienceorthat[]agoodtools there.Atthesametime,exactlyasyousaid,allofourmedicinesoriginallycamefrom plants.Thenwestartedisolatingmolecules,sowecanunderstandbetterwhateach moleculeisdoing.Thenwestartedfindingside-effects.Nowyouknowthata pharmaceuticalresearchcompanythatgoestoanindigenoustribeandsays,"Oh.They usethisproductformigraines.Thisplantformigraines." Theyfindoutwhatmoleculeslikelycauseanyeffectonmigrainesorwhat[]sometimes. Thentheyisolatethem,orsynthesizethem.Thentheyfoundtheseside-effects.They're like,"Well,waitaminute.Theseindigenoustripe[]alltheseside-effects[]begenetics, orwhat'sthedeal?"Theygobacktothatplantsometimesandsay,"Whatmolecule offsetthoseside-effects?"Now,they'vegotanotherdrugtheycansellyou.Youcan havesixpills[]oneplantjusttooffsetthesideeffectsgoingaroundtheoriginal conditionyouweregoingafter.Itjustmakessense.Ifyou'reascientistIdon'tcare whetheryoubelievethatGodmadetheseplantsforusorwehave[]sidethem.Itjust makessensethatourbodiesrecognizethemastheyarehaveallofthesecompounds thatcanworksynergistically. WhenyouapproachtheFDAoraresearchscientistthat'sfamiliarwiththeanti-approval process,nobodytold,"Whycan'tIgetmyplant,the[]medicinethroughthisprocess?" They'lltellyoubasicallyit'sasquarepackthrougharoundholdhavealteredthat.They willsaythat,"Becauseyouhavehundredsandsometimesthousandsofthesedifferent compoundsallworkingwithinyourplantextract,becausewecan'tquantifywhateach oneisdoing,it'sbadscience."Whattheyarereallysayingisthatbecausewe,humanity, arenotsmartenoughorlackthetoolstounderstandwhatallthosecompoundsare doingtogether,it'sbadscience.That'sjustaterribleapproachforthatsameapproach wefindforayear.Again,Ibelievecannabisisgoingtoleadthewaybacktoplant-based medicine,notforcannabisitself,butbecausethesecannabanoids,therearesomuch evidencenow.There'sgoingtobemoreandmoreaswestudythisthattheyworkin conjunctionwithotherplantcompounds. Yourindustryhasnowreachedacriticalmasswhereyouhavethebillionsofdollars? Thatmeansyoucanfundresearchonparwithpharmaceuticalandbigtobaccokindof companies.Atthatpointitgetsharderandharder,becausetheearlieststagestuff,it soundslikethere'samachineouttheretoplaywhacamolewithinnovationaround health.Theyjustbunkcompaniesontheheadallthetime.Theindustryistoobigtodo BPR-JoelStanley Page 17 of 19 Joel: Dave: Joel: Dave: Joel: Dave: Joel: thatrightnow.Maybebigtobaccocouldtakedownthecannabisindustry,butIthinkit's abouttwoyearstoolateforthemtodothat.Theymissedthat. Ithinkso,too.You'reabsolutelyright.Now,therearetools.Thisisoutoftheclosets. Thisisoutoftheblackmarkets,outofourbasements.Now,there'sviablebusinesses thatcaninvestinthatresearchanddevelopment.Ultimately,attheendofthedaywhat themedicalcommunitywantstohavethatfinalpushbackoverintoadvocatingfor botanicalclassesofmedicineswhatitwantsandwhatitneeds,andthisisfine.This meansthatthesearesmartpeople.Itneedsthat,anditneedsthatinformation.We're goingtobeabletogetitnow.Thisnextdecadeofresearchisgoingtobeveryexciting ofwhatwe'regoingtofindout. Joel,thanksforyour[].It'sfantasticstuff.Speakingofdata,likeyoujustsaid,Iwantto gatherthreemorepiecesofdatafromyou,somethingI'veaskedeveryguestonthe show,morethan350episodes,exceptthatoneepisode,number77,whereIforgot.If someonecametoyoutomorrowandsaid,"IwanttokickassateverythingIdo.LikeI wanttoperformbetterasahumanbeing."Whatarethethreemostimportantpiecesof adviseyouhaveforme?Whatwouldyouofferthem,notjustfromyourbusiness,but justfromyourlife? Iwouldsaymeditationhasbeenoneofthemostimportantthingsforme.It'sthattool allowsyoutobewhoyoutrulyare,notwhoyouthinkyouare,notwhoyouweretrying tobe.It'sthatthingthatresetsyou.Ithinkthatthat'sveryimportant.It'salsovery difficulttomeditatewhenyou'renothealthyalready.Diet.Dietisveryimportant.When youputdietandexerciseinit,theyonlygetanotherthingin,sodietandexercise.We count.Let'shavetwothingsasonething. ThenIwillsayfrommylife,notforeveryone'slife,oneofthethingsthatsetmeonthe habitformeditationandforcaringaboutmybodyandmyconsciousness,we'reactually exploringplant-basedmedicines,manyofthemthatarepsychotropic.Beenthrough[]. That'sbeenahugepieceofmywakingupandbecomingwhoIamsupposedtobe. Verywellsaid.I'vehadacoupleepisodeswherewetalkabout[],andI'vecertainlydidit alongtimeago,andPeruwiththeshaman,soIappreciatethatyoubroughtthatup. Notalotofpeopletalkaboutthat,buttheycanbesoprofoundwhenit'sdonerightand notatDisneyLand. Thosearemorethingsthatweneedtounderstandandnotjustsay,"Ohthat'sbad." Whyisitbad?Wedon'tknowwhy,butit'sbad." Thatwouldbeanti-sciencerightthere.Joel,wherecanpeoplefindoutmoreabout Charlotte'sWeb? IfyouwanttoknowaboutCharlotte'sWeb,ifyou'reinterestedintryingtheproduct,go toCWHemp.com,C-W-H-E-M-Pdotcom.Also,there'sagreatcompilationofthe researchoncannabisingeneral,butCBDaswellattheRealofCaringFoundation website,whichiswww.TheRoc.us,wwwdotT-H-E-R-O-CdotUS. BPR-JoelStanley Page 18 of 19 Dave: Joel: Dave: Joel: Dave: Joel: Dave: R-O-CnotR-O-C-K. R-O-C. Gotit.FromtheRealmofCaring. Yougotit. Awesome.ThanksagainforbeingonBulletproofRadio.KeepputtingyourCharlotte's WebCBDextractinourbulletproofcoffee.Haveanawesomeday,Joel. Thankyousomuchforhavingme,Dave. Ifyouenjoyedtoday'sepisode,youknowwhattodo.HeadonovertoiTunes,andleave bulletProofRadioafivestarreviewandtellpeoplewhyyoulikelisteningtoit.While you'reatit,youmightconsidertryingthenewBrainOctane3-ouncebottle.Youwantto haveacoupleofthese,youcanrefillthemfromyour32-ouncebottle,butgettingalittle brainoctaneinyourbodyeverydayorlikeIdowitheverymealeverydaytotally changesyourbrain.Haveanawesomeday. Howdidwedo? Ifyouratethistranscript3orbelow,thisagentwillnotworkonyour futureorders BPR-JoelStanley Page 19 of 19
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