BIOLOGY II NERVOUS SYSTEM ACTIVITY #2 NAME_____________________ DATE___________HOUR_____ NERVE IMPULSE T RANSMISSION OBJECTIVES: 4. 5. Explain how nerve impulses are generated and how they are conducted along a nerve fiber (pp. 200 – 224) Describe the mechanism of nerve impulse transmission at the synapse. (pp. 224 – 227) R ESTING POTENTIAL ACTION POTENTIAL Nervous System Activity #2 page 1 ACTION POTENTIAL – G RAPH Nervous System Activity #2 page 2 T RANSMISSION ACROSS A SYNAPSE Nervous System Activity #2 page 3 QUESTIONS : 1. 2. Match the description with the correct event. ______ More Na+ outside cell More K+ inside cell A. Depolarization ______ Na+ ion gates open and Na+ rush into cell B. Hyperpolarization ______ K+ gates open & Na+ gates close; K+ rush out of cell C. Refractory Period ______ More K+ moved out of cell than necessary to reestablish charge across membrane D. Repolarization ______ Na+ pumped out of cell & K+ pumped into cell E. Resting potential How is the resting potential different from repolarization? _____________________________________________________________ _____________________________________________________________ 3. Answer the following questions regarding the transmission of a nerve impulse. a. What maintains the excess of Na+ outside the cell and an excess of K+ inside the cell during the resting potential stage? ________________________________________________________ b. The resting potential of a neuron (-70mV) indicates that the inside of the cell is more negative than the outside. What two factors cause this negative charge? ________________________________________________________ c. What causes Na+ channels (gates) to open? ________________________________________________________ d. What causes Na+ to rush into the neuron during depolarization? ________________________________________________________ Nervous System Activity #2 page 4 e. What causes K+ to rush out of the neuron during repolarization? ________________________________________________________ f. What causes the neuron to be hyperpolarized? ________________________________________________________ g. What reestablishes the original distribution of K+ and Na+ during the refractory period? ________________________________________________________ 4. Listed below is the distribution / movement of Na+ and K+ during the transmission of a nerve impulse. Put the following in the correct order. ___1__ More Na+ outside the neuron; more K+ inside the neuron ______ Na+ gates open ______ Na+ gates close & K+ gates open ______ Na+ rushes into the neuron ______ K+ rushes out of the neuron ______ More K+ is outside the neuron; more Na+ is inside the neuron ______ Na+ is pumped out of the cell & K+ is pumped into the cell 5. Define the following terms: a. Synapse:________________________________________________ ________________________________________________________ b. Presynaptic neuron:________________________________________ ________________________________________________________ c. Postsynaptic neuron:_______________________________________ ________________________________________________________ Nervous System Activity #2 page 5 6. Shown below is a diagram of a typical synapse. Color the following parts on the diagram. • Presynaptic neuron (A) • Nerve impulse (D) • Presynaptic membrane (E) • Synaptic vesicle (F) • Neurotransmitter (G) • Neurotransmitter fragment 1 (G ) Nervous System Activity #2 page 6 • Exocytosis (H) • Synaptic cleft (I) • Postsynaptic membrane (J) • Receptor (G2) • Endocytosis (K) 7. Match the event below with the correct number from the diagram in question #6. ______ Synaptic vesicles fuse with the presynaptic membrane releasing the neurotransmitter into the synaptic cleft. ______ When the nerve impulse reaches the synaptic end bulb, Ca2 + gates in the axon open allowing Ca2 + to enter the end bulb ______ The neurotransmitter diffuses across the synaptic cleft and bind to the receptors on the postsynaptic membrane ______ The neurotransmitter is broken down; the fragments are then taken into the end bulb by endocytosis ______ The neurotransmitter fragments are used to make new neurotransmitter molecules ______ The flow of Ca2 + into the end bulb causes synaptic vesicles to migrate toward the presynaptic membrane 8. Match the structure with the correct letter from the diagram below. ______ Neurotransmitter ______ Postsynaptic membrane ______ Presynaptic membrane ______ Receptor site (protein) ______ Synaptic cleft ______ Synaptic end bulb ______ Synaptic vesicle Nervous System Activity #2 page 7
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