2014 Descriptive
Vet Path Course
Gross
Exam #1
2014 DESCRIPTIVE VETERINARY PATHOLOGY COURSE
GROSS EXAM #1
1.
Tissue from a mouse.
Name the condition: Ringtail
Cause: Low humidity
2.
Tissue from an ox.
Morphologic Diagnosis: Femoral osteopetrosis
Pathogenesis: Nonfunctional ruffled border on macrophages => no resorption
of mineralized primary spongiosa=> no remodeling of bone
Name another possible lesion in this animal: Brachygnathia, oligo- or
anodontia
3.
Tissue from a dog.
Morphologic Diagnosis: Orbital meningioma
4.
Tissue from a calf.
Morphologic Diagnosis: Segmental necrohemorrhagic enteritis
Cause: Clostridium perfringens type C
5.
Tissue from a water moccasin (a.k.a “cottonmouth”, a North American viper)
Morphologic Diagnosis: Diffuse proliferative and catarrhal gastritis
Cause: Cryptosporidium serpentis
6.
Tissue from a foal.
Morphologic Diagnosis: Segmental catarrhal enteritis
Cause: Parascaris equorum
Name a possible sequela: Impaction or ulceration due to linear foreign body
7.
Tissue from a cat.
Morphologic Diagnosis: Cranial meningioma with pressure atrophy of
underlying cerebrum
8.
Tissue from a turkey.
Morphologic Diagnosis: Diffuse unilateral fibrinonecrotic pneumonia
Name the Condition: Ornithobacterium rhinotracheale (P.multocida OK)
9.
Tissue from a dog.
Pathogenesis: Hepatic macronodular regeneration and fibrosis (cirrhosis)
=>portal hypertension=> development of vestigial (acquired) shunts
10. Tissue from a sheep.
Give two morphologic diagnoses: Focal unilateral cerebral coenurus; bilateral
hydrocephalus
Cause: Coenurus cerebralis
Name the condition: Gid
11. Tissue from a sea lion.
Morphologic Diagnosis: Diffuse chronic lymphoplasmacytic nephritis
Cause: Leptospira icterohemorrhagica (other Lepto species OK)
12. Tissue from a rabbit.
Morphologic Diagnosis: Diffuse fibrinosuppurative pleuropneumonia
Cause: Pasteurella multocida
Name two additional lesions in this animal: Suppurative otitis media, atrophic
rhinitis, suppurative metritis
13. Tissue from a dog.
Pathogenesis: Renal failure=>mineralization of alveolar basement membranes
and vessel walls=>severe pulmonary edema=>”uremic pneumonitis”
14. Tissue from a calf.
Morphologic Diagnosis: Multifocal to coalescing proliferative and ulcerative
dermatitis
Cause: Ovine poxvirus (sheeppox), bovine herpesvirus-2
Name the disease: Lumpy skin disease (pseudolumpy skin if chose bovine
herpesvirus-2)
15. Tissue from a chicken.
Morphologic Diagnosis: Persistent right oviduct
16. Tissue from a dog
Morphologic Diagnosis: Multifocal to coalescing granulomatous pneumonia
Cause: Blastomyces dematitidis (other dimorphic fungi OK)
17. Tissue from a skunk:
Etiologic diagnosis: Sinonasal skrjabinguliasis (Skrjabingylus chitwoodorum)
18. Tissue from an ox.
Pathogenesis: Ingestion of L-shaped wire=>penetration of reticulum into
pericardial sac=>transfer of bacteria=>chronic fibrinosuppurative pericarditis and
epicarditis (“hardware disease’)
19. Tissue from a sheep.
Morphologic Diagnosis: Diffuse hepatic necrosis
Cause: Copper toxicosis
Name another lesion in this animal: Hemolytic anemia; acute tubular necrosis
of the kidney
20. Tissue from a pig.
Morphologic Diagnosis: Diffuse lymphocytic interstitial pneumonia
Cause: Porcine circovirus-2
21. Tissue from a dog.
Morphologic Diagnosis: Bilateral everted laryngeal saccules
Name an additional lesion in this animal: Tracheal ring hypoplasia
22. Tissue from a rabbit.
Morphologic Diagnosis: Multifocal chronic lymphocytic nephritis
Cause: Encephalitozoon cuniculi
Name an additional lesion in this animal: Lymphocytic encephalitis; cataract
23. Tissue from a horse.
Morphologic diagnosis: Multifocal to coalescing granulomatous nephritis
Cause: Halicephalobus gingivalis
24. Tissue from an angelfish.
Morphologic Diagnosis: Focally extensive thyroid hyperplasia (goiter)
25. Tissue from a horse.
Morphologic Diagnosis: Ovarian granulosa cell tumor
26. Tissue from a goat.
Morphologic Diagnosis: Multifocal to coalescing proliferative enteritis (mucosal
hypertrophy and hyperplasia OK)
Cause: Eimeria ninakohlayakimovae (arloingi, christianseni, ovinoidalis)
27. Tissue from a cow.
Morphologic diagnosis: Focally extensive fibrinosuppurative valvuitis and mural
endocarditis (vegetative valvular endocarditis OK)
Name three possible causes: Truperella pyogenes; Bartonella bovis; Staph
aureus; Streptococcus bovis,Truperella pyogenes; Bartonella bovis; Staph aureus;
Streptococcus bovis, E.coli
28. Tissue from a pig.
Morphologic Diagnosis: Multifocal psoraisiform and pustular eosinophilic
dermatitis (proliferative and necrotizing dermatitis OK)
Name the condition: Porcine juvenile pustular and psoriasiform dermatitis or
pityriasis rosea (swine pox OK if proliferative and necrotizing dermatitis was
chosen)
29. Tissue from a sheep.
Morphologic Diagnosis: Multifocal to coalescing grey matter laminar necrosis
(polioencephalomalacia OK, but not quite as descriptive)
Cause: Thiamine deficiency, lead toxicosis, sulfur toxicosis
Name the significance of the special test in the lower left: Breakdown of fat in
necrotic cerebral tissue releases lipochrome pigments which fluoresce under
ultraviolet light
30. Tissue from a pigeon.
Morphologic Diagnosis: Multiple proventricular mucosal granulomas
Cause: Tetrameres Americana
31. Tissue from a chicken.
Morphologic Diagnosis: Hepatic lymphoma (multiple hepatic granulomas OK)
Cause: Avian retrovirus (M. avium OK if granulomas chosen)
32. Tissue from a lamb.
Morphologic Diagnosis: Focally extensive proliferative and ulcerative gingivitis
Cause: Ovine parapoxvirus (contagious ecthyma virus)
33. Tissue from a great blue heron.
Cause: Eustrongylides ignotus
34. Tissue from a sheep.
Morphologic Diagnosis: Nasal adenocarcinoma
Cause: Ovine endogenous beta-retrovirus
35. Tissue from a cat.
Pathogenesis: Prolonged anorexia=>diminished blood glucose=>diminished
insulin releasel=>lipolysis as well as concurrent lack of dietary protein=>
diminished production of apolipoproteins => inability to excrete accumulated
triglycerides from the liver => hepatic lipidosis
36. Tissue from a horse.
Morphologic Diagnosis: focally extensive cervical subcutaneous and muscular
necrosis
Cause: Clostridium septicum, chauvoei, sordelli, etc. (almost any will do)
Name the condition: Malignant edema
37. Tissue from an ox.
Morphologic Diagnosis: diffuse fibrinonecrotic tracheitis
Cause: Bovine herpesvirus-1 (IBR virus 1 point only)
38. Tissue from a chicken.
Morphologic Diagnosis: Multifocal to coalescing granulomatous and necrotizing
osteomyelitis
Cause: Streptococcus hirae, Staphyloccocus aureus
39. Tissue from a goldfish.
Morphologic Diagnosis: Bilateral polycystic kidneys
40. Tissue from a calf.
Morphologic Diagnosis: Diffuse cutaneous hypotrichosis (note this is NOT
alopecia)
Name a second lesion in this individual: Oligodontia
41. Tissue from a cat.
Morphologic Diagnosis: Diffuse dental porphria
Cause: Congenital lack of uroporphyrinogen-3 cosynthetase
Name an associated clinicopathologic abnormality: Hemolytic anemia
42. Tissue from an ox.
Morphologic Diagnosis: Multifocal proliferative abomasitis (or abomasal
mucosal epithelial hyperplasia and hypertrophy)
Cause: Ostertagia ostertagi (or Trichostrongylus circumcincta)
Name an associated clinicopathologic abnormality: Hyperpepsinogenemia,
hypergastrinemia, or hypoproteinemia
43. Tissue from a dog
Morphologic Diagnosis: Diffuse pancreatic hypoplasia
Name a diagnostic biochemical test: Serum trypsin-like immunoreactivity
44. Tissue from a calf.
Morphologic Diagnosis: Leukotrichia
Cause: Copper deficiency
45. Tissue from a raccoon.
Name the agent: Dracunculus insignis
46. Tissue from a carp.
Cause: Flavobacterium columnaris
47. Tissue from a rhesus macaque
Morphologic Diagnosis: Focally extensive pyloric congestion and hemorrhage
Cause: Simian filovirus (Ebola, Marburg, Simian Hemorrhagic fever viruses)
48. Tissue from a pig.
Morphologic Diagnosis: Diffuse massive hepatic necrosis
Cause: Vitamin E/Se imbalance
Name the condition: Hepatosis dietetica
49. Tissue from a fairy bluebird.
Morphologic Diagnosis: Articular (phalangeal) gout
50. Tissue from a dog.
Morphologic Diagnosis: Diffuse intestinal lymphangiectasia
Name a likely breed: Yorkshire terrier, Norwegian Lundehund, soft coated
wheaten terrier