ImmunizationFactsandFigures Nov2015Update Vaccinessavechildren’slives • • • Immunizationisoneofthemostsuccessfulpublichealthinitiatives.Eachyear,vaccinationavertsanestimated 2-3milliondeathsfromdiphtheria,tetanus,pertussis(whoopingcough)andmeasles.Thesearealllife1 threateningdiseasesthatdisproportionatelyaffectchildren . Thankstoimmunization,smallpoxhasbeeneradicatedandweareonthecuspofaworldfreefrompolio. Since2000,GAVI,theVaccineAlliance,ofwhichUNICEFisafoundingpartner,hassupportedthevaccination 2 of500millionchildrenintheworld’spoorestcountries,savinganestimated7millionlives . …Butnearlyoneinfivechildrenstillmissoutonbasicvaccinesthatcouldmeanthedifference betweenlifeanddeath • • • • • Approximately17%ofdeathsinchildrenunderfivearevaccine-preventable.Anestimated1.5millionchildren 3 dieannuallyfromdiseasesthatcanbepreventedbyimmunization . Ifallchildrenwereimmunizedwithexistingvaccines,wecouldsavenearly25millionlivesbetween2011and 4 2020 . In2014,anestimated86percentofinfantsworldwidewerevaccinatedwiththreedosesofthevaccine requiredtofullyimmunizethemagainstdiphtheria,tetanusandpertussis(DTP3vaccine)–upfrom20%in 5 1980 .Thesethreediseasesarepotentiallyfatalforchildrenunder5.(Additionaldatahere: http://data.unicef.org/child-health/immunization.) Morethan60percentofthechildrenwhohavenotreceivedthreedosesofDTP-containingvaccineduring 2014liveintencountries:DemocraticRepublicoftheCongo,Ethiopia,India,Indonesia,Iraq,Nigeria,Pakistan, 6 Philippines,UgandaandSouthAfrica . Childrenwhoareborntoundereducatedwomenarethemostlikelytobeunimmunized.Ifallmothersinlow andmiddleincomecountrieshadprimaryeducation,childvaccinationagainstdiphtheria,tetanusand whoopingcoughwouldincreaseby10%.Childvaccinationagainstthesediseaseswouldincreaseby43%ifall 7 mothersinthesecountrieshadsecondaryeducation . Polio: • • Wearecloserthanevertoendingpolio.In1988therewere350,000casesofpoliointheworldandin2014, only359.Neverbeforeinthehistoryofthediseasehavetherebeensofewchildreninsofewcountrieswith 8 thecripplingvirus . Today,thankstotheglobaleffortforpolioeradication,allbutjusttwocountries(AfghanistanandPakistan) 9 haveeliminatedpoliowithintheirborders . 1 http://www.who.int/mediacentre/factsheets/fs378/en/ http://gaviprogressreport.org/2014/#page=15 GAVI 2014 Annual Report Page 7# 3 http://apps.who.int/immunization_monitoring/diseases/en/ and http://www.who.int/gho/immunization/en/ - 2008 4 Global Vaccine Action Plan, p. 116 5 http://www.unicef.org/immunization/files/Global_immunization_coverage.pdf 6 http://www.who.int/immunization/monitoring_surveillance/Global_Immunization_Data.pdf?ua=1 7 Education for All Monitoring Report 2013/14, p. 160: http://www.uis.unesco.org/Library/Documents/gmr-2013-14teaching-and-learning-education-for-all-2014-en.pdf 8 http://www.who.int/mediacentre/factsheets/fs114/en/ 9 http://www.polioeradication.org/ 2 Measles: 10 • Measlesvaccineshaveavertedanestimated17.1milliondeathsbetween2000and2014 . • • Measlescontinuestokillabout400childreneachday,mainlyinAfricaandAsia . In2014,morethan60percentoftheestimated21.5millionchildrenwhowerenotvaccinatedagainst measles,liveinonlysixcountries:India,Nigeria,Pakistan,Indonesia,Ethiopia,andtheDemocraticRepublicof 12 Congo . 11 Maternalandneonataltetanus: • • 13 Maternalandneonataltetanusisadiseasethatkilled49,000newbornsin2013alone . Whilethediseasehasbeeneliminatedfrom35outof59high-riskcountriessince1999throughvaccination,it 14 persistsaspublichealthproblemin24countries,mainlyinAfricaandAsia .Thisisa94%reductionfrom 15 1998 . Newvaccinescanprotectagainstpneumoniaanddiarrhea16-themostprevalentandlethalinfections forchildren. • • • 17 Aquarterofchilddeathsareduetopneumoniaordiarrhoea . Bytheendof2014,UNICEFhelpedprotectover47millionchildrenfrompneumoniabysupportingthe 18 introductionofthepneumococcalconjugatevaccinein73Gavi-supportedcountries . WithsupportfromUNICEF,over20millionchildrenwereprotectedfromseverediarrhoeawiththerotavirus vaccine.Severediarrhoeakillsover531,000childreneachyear. Oralcholeravaccine19 • • In2014,UNICEFandpartnerssupportedfivecountriesinstockpilingdosesoftheoralcholeravaccine: Ethiopia,SouthSudan,Guinea,HaitiandNepal. Theglobalstockpileofcholeravaccineshashelpedvaccinate600,000peopletodate. UNICEF’sRoleinworldwidechildhoodimmunization: • • • 10 UNICEFanditspartnerssupportimmunizationprogrammesin100countriestohelpallchildrenreachtheirfull potential.Activitiesinclude: o Communicationfordevelopmenttoworkwithcommunitiesandcreatedemandforvaccines. o Vaccineprocurementandcoldchain:forvaccinepurchasesanddelivery,improvingcoldchainsand monitoring.In2014,UNICEFprocured2.71billiondosesofvaccinesforavalueofnearlyUS$1.5billion. o Policysupportandtechnicalassistancetohelpgovernmentpartnerstoimproveroutineimmunization servicesandrolloutimmunizationcampaignsmoreeffectively,toreacheachandeverylastchild. UNICEFistheworld’slargestbuyerofvaccines,reaching40%oftheworld’schildren. UNICEFisacorepartneroftheGlobalAllianceforVaccinesandImmunization(GAVI),theMeaslesandRubella Initiative;theMaternalandNeonatalTetanusElimination(MNTE)initiative;andtheGlobalPolioEradication Initiative(GPEI),inadditiontoworkingcloselywithsisterUNAgencies,donorandprogrammecountries governments,internationaldevelopmentandfinanceorganizationsandthepharmaceuticalindustrytomake immunizationaccessibletoallchildren. http://www.who.int/mediacentre/news/releases/2015/measles-vaccination/en/ http://www.measlesrubellainitiative.org/resources/advocacy-tools/2015-fact-sheet/ 12 http://www.measlesrubellainitiative.org/wp-content/uploads/2015/04/measles-factsheet2015.pdf 13 http://www.who.int/immunization/diseases/MNTE_initiative/en/ 14 http://www.who.int/mediacentre/factsheets/fs378/en/ 15 ibid 16 CHERG-WHO 2014 and http://www.gavi.org/about/mission/facts-and-figures/ 17 ibid 18 http://gaviprogressreport.org/2014/ p.21 19 GAVI 2014 progress report. P.21 11 ***************Aboutvaccine-preventablechildhooddiseases****************** • Diphtheriaisaseriousdiseasecausedbyapotentbacterialtoxin.Itcausesathickcoatinginthebackofthe i noseorthroatthatmakesithardtobreatheorswallow.Itcanbedeadly . • HepatitisBisaseriousinfectionthataffectstheliver.Itleadstochronicliverdiseaseandputspeopleathigh 20 riskofdeathfromcirrhosisandcancerofliver . • HaemophilusinfluenzaetypeB(Hib)cancauseacuterespiratoryinfections,meningitisandotherserious diseasesalmostexclusivelyinchildrenundertheageof5. • Measlesisahighlycontagiousrespiratorydiseasecausedbyavirus .Measlescausesfever,runnynose,cough andrashesalloverthebody.In2014,therewere114900measlesdeathsglobally–about314deathsevery dayor13deathseveryhour. • Pertussis(whoopingcough)isahighlycontagiousrespiratorydisease,whichproducesviolent,uncontrollable coughingwhichoftenmakesithardtobreathe.Pertussismostcommonlyaffectsinfantsandyoungchildren iii andcanbefatal,especiallyinbabieslessthan1yearofage . • Pneumococcaldiseasecancausepneumonia,meningitis,orbloodinfection.Initsworstforms,pneumococcal iv diseasekillsoneinthreepeoplewhocontractit .Pneumoniaisoneoftheleadingcausesofchilddeath aroundtheworld. • Polio(poliomyelitis)mainlyaffectschildrenunderfiveyearsold.Onein200infectionsleadstoirreversible v paralysis.Amongthoseparalyzed,5%to10%diewhentheirbreathingmusclesbecomeimmobilized . • Rotavirusistheleadingcauseofseverediarrhoeaininfantsandyoungchildren.Globally,diarrhoeacauses vi morethanhalfamilliondeathseachyearinchildrenunder5 . • Childrenwhosemothershaverubelladuringtheearlystagesofpregnancyoftencontractcongenitalrubella syndrome(CRS).ChildrenwithCRSarebornwithlifelongdisabilitiesandareatriskforotherdevelopmental vii problemssuchascongenitalheartdiseaseandmentalretardation . • Mothersandtheirnewbornscontracttetanus,anextremelydeadlydisease,whendeliverieshappenin viii unhygienicconditions–especiallyinremoteandareas withoutaccesstohealthfacilities .Tetanuscanbe easilypreventedbytetanusvaccines,hygienicdeliveryandgoodcordcarepractices. • Tuberculosis(TB)isadiseasethattypicallyattacksthelungs.Ifnottreatedproperly,TBdiseasecanbefatal . • Yellowfeverisfoundintropicalclimatesandistransmittedtohumansbythebiteofaninfectedmosquito. Illnessrangesinseverityfromaself-limitedfebrileillnesstosevereliverdiseasewithbleeding.Upto50%of x peoplewhodevelopsevereillnessandarenottreatedmaydie . ii ix i http://www.who.int/ith/diseases/diphtheria/en/ http://www.who.int/mediacentre/factsheets/fs286/en/index.html iii http://www.who.int/immunization_monitoring/diseases/pertussis/en/ iv http://www.cdc.gov/vaccines/vpd-vac/pneumo/default.htm#disease v http://www.who.int/mediacentre/factsheets/fs114/en/ vi http://www.who.int/nuvi/rotavirus/en/ vii http://www.who.int/mediacentre/factsheets/fs367/en/ viii http://www.unicef.org/media/media_45487.html?p=printme ix http://www.who.int/mediacentre/factsheets/fs104/en/index.html x http://www.who.int/mediacentre/factsheets/fs100/en/ ii 20 http://www.who.int/mediacentre/factsheets/fs204/en/
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