Body and Behavior ESSENTIAL QUESTIONS • How do internal functions of the body affect behavior? • How do changes in our body’s processes lead to changes in our behavior? netw rks There’s More Online about the body and behavior. CHAPTER 6 Lab Activity Reflexive Reaction Lesson 1 The Basics of the Nervous System Lesson 2 Studying the Brain Lesson 3 The Endocrine System Lesson 4 Heredity and Environment Psychology Matters… Our body’s systems work together, with the brain as a conductor, to pull off amazing feats. Climbing a mountain, reading a book, missing your grandmother, or writing a poem are all based on biological processes that take place within and between cells. The nervous and endocrine systems, produced by your genes, interact with the environment to produce your behaviors. Psychology includes the study of how these systems operate. An athlete gets the body in shape by practicing a move or action over and over again. The mind and body are working together and interacting with the environment. ranplett/the Agency Collection/Getty Images 145 CHAPTER 6 Lab Activity Reflexive Reaction THE QUESTION... RESEARCH QUESTION Does time spent playing video games improve our reflexes? Have you ever watched a horror movie and gotten sweaty palms? That’s your body and your mind working together. Have you ever woken up and been so sluggish you fumbled with your alarm clock? That’s your body and mind not working together so well. The connection between mind and body is what allows us to get around and to form behaviors. Researchers are finding that some of our everyday habits— especially the very repetitive ones—might have the ability to change how our bodies function. Perhaps these habits are even improving us. Is it possible that playing video games improves our reflexes? This experiment will attempt to find out. Psychology Journal Activity Think about your daily habits and which ones are newer than others. Write about this in your Psychology Journal. Think about these questions as you write: Do you feel like everyday habits are physical or mental? Which do you think has a bigger role—your body or your mind—in forming your everyday habits? 146 FINDING THE ANSWER... HYPOTHESIS Playing video games improves your reflexes. THE METHOD OF YOUR EXPERIMENT MATERIALS 12 inch ruler, ten surveys rating experience with video games PROCEDURE Conduct the Ruler Drop Test with ten participants to test their reaction times. Hold the ruler at the end with 12 on it and let it hang down. Instruct participants to put their finger and thumb around the bottom end of the ruler. Tell them that you will drop the ruler (without advance warning) and that they should catch it as fast as they can. Measure the participant’s reaction times by recording how far the ruler dropped (measuring from the top side of his or her thumb). The distance in inches or centimeters will represent their reaction times. Test each participant three times and find the average. Next, ask each participant to fill in their survey with their age and gender, and to rate their experience with video games: a 1 means they spend more than 20 hours per week playing video games; a 2 means they play 5–20 hours per week; and a 3 means they play fewer than 5 hours per week. DATA COLLECTION Analyze the data, noting any trends and relationships. Calculate the average reaction times (measured in inches) for the three different ratings. ANALYSIS & APPLICATION 1. Did your results support the hypothesis? 2. What trends or relationships were you able to see in the data before you calculated the averages for each rating? Why were the data easier to analyze once you had the averages? 3. Why do you think playing video games might improve one’s reflexes? Mike Kemp/Rubberball/Getty Images netw rks ONLINE LAB RESOURCES Online you will find: • An interactive lab experience, allowing you • A Skills Handbook that includes a guide for to put principles from this chapter into practice using the scientific method, creating in a digital psychology lab environment. This experiments, and analyzing data. chapter’s lab will include an experiment • A Notebook where you can complete your allowing you to explore issues fundamental to Psychology Journal and record and analyze body and behavior. your experiment data. Body and Behavior 147 netw rks There’s More Online! DIAGRAM Anatomy of Two Neurons DIAGRAM The Nervous System DIAGRAM The Synapse SELF-CHECK QUIZ LESSON 1 The Basics of the Nervous System ESSENTIAL QUESTION • How do internal functions of the body affect behavior? Academic Vocabulary • regulate • voluntary Content Vocabulary • central nervous system (CNS) • spinal cord • peripheral nervous system (PNS) • neurons • synapse • neurotransmitters • somatic nervous system (SNS) • autonomic nervous system (ANS) TAKING NOTES: Key Ideas and Details LABELING Use a graphic organizer like the one below to label, define, and describe the neuron’s three basic parts. 1 2 3 148 It Matters Because We can’t do anything without our nervous systems. The nervous system allows us to think, move, create, and react to our environment. Messages are sent throughout the nervous system constantly. Learning about the nervous system helps us know how messages that are sent to and from the brain cause behavior. How the Nervous System Works GUIDING QUESTION What are the three basic parts of a neuron? The nervous system is never at rest. There is always a job for it to do. It is working right along with you during the most demanding part of your day. Even when you are fully relaxed or sound asleep, your nervous system is busy regulating your body’s functions. The nervous system controls your emotions, movements, thinking, and behavior. It is a part of almost everything you do. Structurally, the nervous system is divided into two parts. The first part is the central nervous system (CNS), which includes the brain and the spinal cord. The second part is the peripheral nervous system (PNS), which is made up of the smaller branches of nerves that reach the other parts of the body. The nerves of the peripheral system transmit information back and forth from the organs to the central nervous system. The nerves of the peripheral system branch beyond the spinal column and range in thickness from the size of a pencil to almost microscopic in the body’s extremities. All parts of the nervous system are protected in some way. The brain is encased inside the skull and is also protected by several layers of sheathing. These layers of sheathing, which also protect the peripheral nervous system, not only protect the brain and nerves from physical damage, but also help to insulate them from extremities in temperature. The spinal cord is sheltered by the skeletal vertebrae of the spine. The bony protection of the vertebrae is vital to the spinal cord. An injury to the spinal cord could prevent the transmittal of messages between the brain and the muscles, and could result in paralysis. Adam Hart-Davis/Photo Researchers, Inc. Reading HELPDESK DESK Neurons Messages to and from the brain travel along the nerves, which are strings of long, thin cells called neurons. Chemical-electrical signals travel down the neurons much as a flame travels along the fuse of a firecracker. The main difference is that unlike a firecracker, the neuron can be “fired” over and over again, hundreds of times a minute. Transmission between neurons, or nerve cells, occurs whenever the cells are stimulated past a minimum point and emit a signal from other neurons or body sensors. The neuron is said to fire in accord with the all-or-none principle, which states that when a neuron fires, it does so at full strength. If a neuron is not stimulated past the minimum, or threshold, level, it does not fire at all. Neurons have four basic parts: dendrites, the cell body, an axon, and axon terminals. Dendrites are short, thin fibers that protrude from the cell body that receive impulses, or messages, from other neurons. The dendrites are like antennae for the neuron. Along the dendrites are thousands of synapses receiving impulses for the neuron. These impulses are then sent to the cell body to be processed. The cell body integrates the signals, or impulses, from other cells. The cell body also contains the cell’s genetic information, called DNA. This information is found in the nucleus of each cell in our bodies. In addition, the cell body provides metabolic support for the cell, meaning that the parts of the cell body work together to give the cell energy for continued support and maintenance. Without the reactions inside the cell body, the cell would not be able to maintain life. regulate to control something central nervous system (CNS) the brain and spinal cord spinal cord nerves that run up and down the length of the back and transmit most messages between the body and brain peripheral nervous system (PNS) nerves branching beyond the spinal cord into the body neurons the long, thin cells of nerve tissue along which messages travel to and from the brain DIAGRAM THE NERVOUS SYSTEM The nervous system is divided into two parts: the central nervous system (CNS) and the peripheral nervous system (PNS). CRITICAL THINKING 1. Gathering Information What are the two main divisions of the peripheral nervous system? 2. Comparing and Contrasting What are the similarities and differences between the sympathetic and parasympathetic nervous systems? Body and Behavior 149 DIAGRAM ANATOMY OF TWO NEURONS The human body contains billions of neurons. The neuron receives messages from other neurons via its dendrites. The messages are then transmitted down the axon and sent out through the axon terminals. The myelin sheath serves to protect the axon. CRITICAL THINKING 1. Drawing Conclusions What is the function of the dendrites? 2. Gathering Information What is the role of the myelin sheath? There is a constant flow of chemical energy within the parts of the cell body. Body signals move from the cell body to the axons. The axons can reach to distant areas of the nervous system, delivering impulses to the parts of the body they are intended to reach. The electrical signals along axons usually move quickly, but in length can stretch to several feet. Clusters of axons may split into several branches so that their intended targets can be reached. For example, a message may travel from the dendrite of a neuron, through the cell body, and then to the part of the body that reacts to that message. The single extended axon carries the impulses from the cell body toward the axon terminals, which release neurotransmitters to stimulate dendrites of the next neuron. The shape and structure of dendrites make them particularly easy to move, shape, or mold. This plasticity plays an important role in learning, memory, and recovery after spinal cord or brain injury. When new dendrites grow or existing ones grow new connections, long-term memory may improve. In addition, adaptive behaviors, learned behaviors, and retention of memories are possible over a lifetime because of the plasticity of dendrites. A white, fatty substance called the myelin sheath insulates and protects the axon for some neurons. In cases of multiple sclerosis, the myelin sheath is destroyed, and as a result, the behavior of the person is erratic and uncoordinated. The myelin sheath also speeds the transmission of impulses. Small fibers, called axon terminals, branch out at the end of the axon. Axon terminals are positioned opposite the dendrite of another neuron. synapse the gap that exists between individual nerve cells neurotransmitters the chemicals released by neurons, which determine the rate at which other neurons fire 150 Making Neural Connections Looking closely at the diagram of the neuron, you can see that there is a small space or gap between the axon terminals of one neuron and the dendrites of another neuron. This space between the neurons is called the synapse. The synapse is a junction or connection between neurons. A neuron transmits its impulses or messages to another neuron across the synapse by releasing chemicals that are known as neurotransmitters. These neurotransmitters open chemical locks or “excite” the receptors. The neurotransmitters can excite the next neuron or stop it from transmitting altogether, which is called inhibition. With receptors only in the dendrites, the synapse allows signals to move in only one direction, from endfoot to dendrite. Different types of neurotransmitters do different jobs for the body. Some, called excitatory neurotransmitters, excite the receptors and cause action among neurons. Others are inhibitory neurotransmitters, which prevent potential action among neurons. Glutamate is an excitatory neurotransmitter that plays an important role in memory, learning, and communication among receptors. Gammaaminobutyric acid (GABA) receptors play a role in quieting the body and muscles. Both of these neurotransmitters play an important part in the effects of alcohol on the body. Glutamate receptors are slowed down when alcohol is consumed, and body functions are affected. GABA receptors work harder, which is what causes alcohol to work as a depressant that slows down the body. Other neurotransmitters have other effects on the body. Like glutamate, norepinephrine is involved in memory and learning. Endorphins inhibit pain. The oversupply or undersupply of certain neurotransmitters has been linked to certain diseases. For instance, an undersupply of acetylcholine, a neurotransmitter involved in movement and memory, is associated with paralysis and Alzheimer’s disease. An oversupply of dopamine, involved in learning, emotional arousal, and movement, is linked to schizophrenia, while an undersupply is linked to Parkinson’s disease. An undersupply of norepinephrine and serotonin may result in depression. Medications that increase levels of norepinephrine are used to treat Attention Deficit Hyperactivity Disorder and hypotension as well. Neural Activity The intensity of activity in each neuron depends on how many other neurons are acting on it. Each individual neuron is either ON or OFF, depending on whether most of the neurons acting on it are exciting it or inhibiting it. The actual destination of nerve impulses produced by an excited neuron, as they travel from one neuron to another, is limited by what tract in the nervous system they are on. Ascending tracts carry sensory impulses to the brain, and descending tracts carry motor impulses from the brain. There are different types of neurons. Afferent neurons, or sensory neurons, relay messages from the sense organs (including eye, ear, nose, and skin) to the brain. When you smell food cooking, afferent neurons stimulated in your nose react with a chemical signal to your brain. The brain may then be able to identify the smell without you being able to see or taste the food. Efferent neurons, or motor neurons, send signals from the brain to the glands and muscles. When you walk, move, exercise, or interact with your environment, efferent neurons help the brain coordinate the movement. Interneurons process signals, connecting only to other neurons, not to sensors or muscles. You may find interneurons connecting to either afferent neurons or efferent neurons. DIAGRAM THE SYNAPSE Neurons do not touch one another. Instead, a neuron sends its messages across a gap called a synapse by releasing neurotransmitters. These neurotransmitters are received by the dendrite of another neuron. CRITICAL THINKING 1. Sequencing How are neurons involved in sending a message to the brain to raise your arm to answer a question? 2. Drawing Inferences What transports neurotransmitters through the axon? READING PROGRESS CHECK Summarizing How does the nervous system send messages throughout the body? Body and Behavior 151 Voluntary and Involuntary Activities GUIDING QUESTION How do the sympathetic and parasympathetic nervous systems differ? When your pupils get larger in response to dim light, your body is performing an involuntary activity. CRITICAL THINKING Categorizing What other involuntary activities take place in your body? voluntary proceeding from one’s own consent somatic nervous system (SNS) the part of the peripheral nervous system that controls voluntary movement of skeletal muscles Some of the actions that your body makes in response to impulses from the nerves are voluntary acts, such as lifting your hand to turn a page (which actually involves many impulses to many muscles). Others are involuntary acts, such as changes in the heartbeat, in the blood pressure, or in the size of the pupils. The term somatic nervous system (SNS) refers to the part of the peripheral nervous system that controls voluntary activities. The term autonomic nervous system (ANS) refers to the part of the nervous system that controls involuntary activities, or those that ordinarily occur automatically, such as heartbeat, stomach activity, and so on. The autonomic nervous system has two parts: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system prepares the body for dealing with emergencies or strenuous activity. It speeds up the heart rate to hasten the supply of oxygen and nutrients to body tissues. It constricts some arteries and relaxes others so that blood flows to the muscles, where it is most needed in emergencies and strenuous activity. It increases the blood pressure and suspends some activities, such as digestion. In contrast, the parasympathetic nervous system works to conserve energy and to enhance the body’s ability to recover from strenuous activity. It reduces the heart rate and blood pressure and helps bring the body back to its normal resting state. All of this takes place automatically. Receptors are constantly receiving messages, such as messages about hunger or the need to swallow or cough, that alert the autonomic nervous system to carry out routine activities. Imagine how difficult it would be if you had no autonomic nervous system and had to think about it every time your body needed to digest a sandwich or perspire. READING PROGRESS CHECK Finding the Main Idea Which nervous systems are responsible for voluntary and involuntary activities? autonomic nervous system (ANS) the part of the peripheral nervous system that controls internal biological functions LESSON 1 REVIEW 1. Defining What is the difference between afferent and efferent neurons? What are interneurons? Using Your Notes 2. Diagramming Using the notes you took during this lesson, create a diagram of the different parts of the nervous system. Answering the Guiding Questions 3. Describing What are the three basic parts of a neuron? 152 4. Applying How do the sympathetic and parasympathetic nervous systems work? Writing Activity 5. Informative/Explanatory Put your pen or pencil down and then pick it up. Write a paragraph identifying and describing the parts of the nervous system that caused those movements to happen. Adam Hart-Davis/Photo Researchers, Inc. Reviewing Vocabulary netw rks There’s More Online! DIAGRAM Brain Activity on a PET Scan DIAGRAM Cerebral Cortex DIAGRAM Functions of the Brain’s Hemispheres DIAGRAM Parts of the Brain SELF-CHECK QUIZ LESSON 2 Studying the Brain ESSENTIAL QUESTION • How do internal functions of the body affect behavior? Reading HELPDESK DESK Academic Vocabulary • detect • stimulate Content Vocabulary • hindbrain • midbrain • forebrain • lobes • electroencephalograph (EEG) • computerized axial tomography (CT) • positron emission tomography (PET) • magnetic resonance imaging (MRI) TAKING NOTES: Key Ideas and Details LABELING Use a graphic organizer like the one below to label the parts of the hindbrain and forebrain. (c)Phanie/SuperStock; (r)Paul Burns/Blend Images/Corbis Hindbrain Forebrain It Matters Because Even after centuries of study, parts of the human brain remain a mystery even to scientists. The knowledge we gain, the memories we have, and even the bodily functions that we rely on for life are managed and regulated in the brain. Understanding how the brain works can help us to understand the brain’s effect on our lives. The Three Brains What are the three parts of the human brain? What are the specializations of the left and right hemispheres of the brain? GUIDING QUESTIONS The brain is composed of three parts: the hindbrain, midbrain, and forebrain. The hindbrain, located at the rear base of the skull, is involved in the most basic processes of life. The hindbrain includes the cerebellum, medulla, and the pons. The cerebellum, located behind the spinal cord, helps control posture, balance, and voluntary movements; the medulla controls breathing, heart rate, and a variety of reflexes; the pons functions as a bridge between the spinal cord and the brain. The pons is also involved in producing chemicals the body needs for sleep. The midbrain is a small part of the brain above the pons. It arouses the brain, integrates sensory information, and relays it upward. The medulla and pons extend upward into the midbrain. The medulla, pons, and midbrain compose most of the brain stem, and the reticular activating system (RAS) spans across all these structures. The RAS alerts the rest of the brain to incoming signals and is involved in the sleep/wake cycle. The forebrain, covering the brain’s central core, includes the thalamus, which integrates sensory input. The thalamus is a relay station for all the information that travels to and from the cortex. All sensory information with the exception of smell enters the thalamus. All information from the eyes, ears, and skin enters the thalamus and then is sent to the appropriate areas in the cortex. Just below the thalamus is the hypothalamus. It controls functions such as hunger, thirst, and sexual behavior. It also controls the body’s reactions to changes in temperature, so when we are warm, we begin to sweat, and when we are cold, we shiver. Body and Behavior 153 DIAGRAM PARTS OF THE BRAIN The brain is the largest, most complex part of the nervous system. CRITICAL THINKING 1. Analyzing What are the functions of the cerebellum? RH.11–12.7 2. Gathering Information In what part of the brain is the medulla located? RH.11–12.7 hindbrain a part of the brain located at the rear base of the skull that is involved in the basic processes of life midbrain a small part of the brain above the pons that arouses the brain, integrates sensory information, and relays it upward forebrain a part of the brain that covers the brain’s central core, responsible for sensory and motor control and the processing of thinking and language The higher thinking processes—those that make us unique—are housed in the forebrain. The outer layer of the forebrain consists of the cerebral cortex. The inner layer is the cerebrum. The cerebral cortex and cerebrum surround the hindbrain and brain stem like the way a mushroom surrounds its stem. The cerebral cortex gives you the ability to learn and store complex and abstract information, and to project your thinking into the future. Your cerebral cortex allows you to see, read, and understand this sentence. The cortex, or bark, of the cerebrum is the site of your conscious thinking processes, yet it is less than one-fourth-inch thick. The limbic system, found in the core of the forebrain, is composed of a number of different structures in the brain that regulate our emotions and motivations. The limbic system includes the hypothalamus, amygdala, thalamus, and hippocampus. The amygdala controls violent emotions, such as rage and fear. The hippocampus is important in the formation of memories. If the hippocampus were damaged, it would be difficult to form new memories. Lobes and Hemispheres lobes the different regions into which the cerebral cortex is divided 154 All of these parts are covered by the cerebrum. The cerebrum is really two hemispheres, or two sides. The cerebral hemispheres are connected by a band of fibers called the corpus callosum. Each cerebral hemisphere has deep grooves, some of which mark regions, or lobes. The occipital lobe is where the visual signals are processed. Damage to this area can cause visual problems, even selective or total blindness. The parietal lobe is concerned with information from the senses from all over the body. The temporal lobe is concerned with hearing, memory, emotion, and speaking. The frontal lobe is concerned with organization, planning, and creative thinking. The front of the parietal lobe receives information from the skin and muscles. The number of touch sensors in an individual body part determines its sensitivity, and, along with the complexity of the part’s movement, governs the amount of brain tissue that is associated with the part. The complex touch and movements of the hands, for example, involve more brain area than the more limited calves. The somatosensory cortex, at the back of the frontal lobe, receives information from the touch sensors. The motor cortex sends information to control body movement. The more sophisticated the movements, such as those used in speaking, the bigger the brain area involved in their control. The association areas mediate between the other areas and do most of the synthesizing of information. For example, association areas turn sensory input into meaningful information. Different neurons are activated when we see different shapes and figures. The association areas arrange the incoming information into meaningful perceptions, such as the face of a friend or a favorite shirt. There is much concern that information about properties of the left and right hemispheres is misinterpreted. Popular books have oversimplified the properties of the two hemispheres. In reality, the left and right sides complement and help each other, so be aware of this as we list the properties of each hemisphere. The two hemispheres in the cortex are roughly mirror images of each other, and each of the four lobes is present in both hemispheres. The corpus callosum carries messages back and forth between the two hemispheres to jointly control human functions. Each hemisphere is connected to one-half of the body in a crisscrossed fashion. The left hemisphere controls the movements of the right side of the body. For most people, the left side of the brain is where speech is located. The left side also is specialized for mathematical ability, calculation, and logic. The right hemisphere controls the left side of the body. Thus a stroke that causes damage to the right hemisphere will result in numbness or paralysis on the left side of the body. The right hemisphere is more adept at visual and spatial relations. Putting together a puzzle requires spatial ability. Perceptual tasks seem to be processed primarily by the right hemisphere. The right side is better at recognizing patterns. Thus, music and art are better understood by the right hemisphere. Creativity and intuition are also found in the right hemisphere. In a normal brain, the two hemispheres communicate through the corpus callosum. Whatever occurs on one side is communicated to the other side. Some people have grand mal seizures, which is the most severe kind of seizure. DIAGRAM CEREBRAL CORTEX Functions of the cerebral cortex are not fully understood. Below are areas important to behavior. CRITICAL THINKING 1. Analyzing Visuals What is the function of the motor cortex? RH.11–12.7 2. Gathering Information In which part of the brain are body sensations experienced? RH.11–12.7 Body and Behavior 155 detect to find out or discover stimulate to raise levels of interest, response, or activity DIAGRAM FUNCTIONS OF THE BRAIN’S HEMISPHERES Being “right-brained” or “leftbrained” is an exaggerated concept. We constantly use both hemispheres of our brain, as each hemisphere is specialized for processing certain kinds of information. CRITICAL THINKING 1. Assessing In what topics or activities does the right hemisphere specialize? RH.11–12.7 2. Analyzing What part of the brain would someone use to solve a complex word problem? RH.11–12.7 156 Separating the brain hemispheres has proven to lessen the number and severity of the seizures. As a result, the person has a split brain. The person has two brains that operate independently of each other. Since the corpus callosum is severed, there can no longer be any communication between the hemispheres. Studies have shown that normal functioning remains possible in such a situation. Many psychologists became interested in differences between the cerebral hemispheres when split-brain operations were tried on epileptics like Harriet Lees. For most of her life Lees’s seizures were mild and could be controlled with drugs. However, at age 25 they began to get worse, and by 30 Lees was having as many as a dozen violent seizures a day. An epileptic seizure involves massive uncontrolled electrical activity that begins in either hemisphere and spreads across both. To enable Lees to live a normal life, she and the doctors decided to sever the corpus callosum so that seizures could not spread. Not only did the operation reduce the severity of seizures, but it also resulted in fewer seizures. Psychologists were even more interested in the potential side effects of this operation. Despite the fact that patients who had this operation now had two functionally separate brains, they seemed remarkably normal. Researchers went on to develop a number of techniques to try to detect subtle effects of the split-brain operation. If a blindfolded man whose brain has been split holds a ball in his right hand, he would be able to say it is a ball. Place the ball in his left hand and he would not be able to say what it is. Information from the left hand is sent to the right hemisphere of the brain. Since the corpus callosum is severed, information cannot cross to the speech center in the left hemisphere. Another experiment with split-brain patients involves tactile stimulation, or touch. In this experiment, objects are held in a designated hand but are blocked from the split-brain patient’s view. Researchers project a word describing an object on a screen to either the right or left visual field. The patient’s task is to find the object corresponding to the word they are shown. When words are presented Quick Lab CAN YOU DETERMINE WHETHER THE LEFT OR RIGHT HEMISPHERE OF THE BRAIN IS DOMINANT? The left hemisphere controls the movements of the right side of the body. This side of the brain is adept at language-related skills, mathematical ability, and logic. The right hemisphere controls the movements of the left side of the body. It is also the side that is more adept for creativity, intuition, and creative expressions such as art and music. Can you tell which side is dominant in people you know? Procedure 1. Think about two of your friends or family members. 2. Compare them in terms of the areas that they seem to be most adept at— mathematics, logical thinking, musical ability, art, or speech. 3. Record your observations in a two-column chart. Analysis 1. Based on your observations, which hemisphere seems to be dominant in each individual? for the right hemisphere to see, patients cannot say the word, but they can identify the object with their left hand touching it behind the screen. To explore emotional reactions in split-brain individuals, researchers designed a test to incorporate emotional stimuli with objects in view. In one of these experiments, a picture of a nude person was flashed to either hemisphere. When researchers flashed the picture to the left hemisphere, the patient laughed and described what she saw. When the same was done to the right hemisphere, the patient said nothing, but her face became flush and she began to grin. Research on split-brain patients has presented solid evidence that each hemisphere of the brain is unique with specialized functions and skills. Individuals who have had split-brain operations remained practically unchanged in intelligence, personality, and emotions. Using the Brain Have you ever been told that people use only about 10 percent of their brains? It’s a common belief, but scientists have proved that this myth is false. It is true that if we explored our brain’s complete cognitive potential we could use a lot more of our brain’s power than we use from day to day. But scientists are now discovering that our daily activities actually tap into a large portion of our brains. In fact, the brain uses about 20 percent of the body’s total energy. Think about when you ride a bicycle. You are coordinating the movement of your arms and legs. At the same time you are evaluating the environment around you, reading signs and interpreting what the signs mean to you. You are also calculating where you are and how far it is to your destination. Different parts of the brain are used to do this interpreting and thinking. Reading a stop sign uses parts of your brain associated with interpreting written language. Determining when you need to hit the brakes to stop in time, your brain connects to your legs and feet, coordinating smooth body movements and checking environmental factors around you at the same time. This coordination involves significant brain activity. READING PROGRESS CHECK Understanding Relationships What is the difference between the left and the right hemispheres of the brain? Body and Behavior 157 How Psychologists Study the Brain GUIDING QUESTIONS How can accidents that damage the brain instruct us in its functions? How do researchers use MRIs to learn about the brain? Scientists use an electroencephalograph (EEG) to measure brain waves. CRITICAL THINKING Assessing What have psychologists observed about the electrical activity of the brain? Mapping the brain’s fissures and inner recesses has supplied scientists with fascinating information about the role of the brain in behavior. Psychologists who do this kind of research are called physiological psychologists, psychobiologists, or neuroscientists. Some research techniques are better at studying the structure of the brain rather than its functions. Scientists must carefully choose which method they want to pursue for studying the brain, depending on what they want to find out. Working with human subjects must always be as ethical as possible to avoid any physical or emotional harm to the subjects. In the past, an intrusive method called a lobotomy was used to treat severe mental illness. During this surgical procedure, an incision was made into the prefrontal lobe of the brain and nerve pathways in the brain were severed. While lobotomies had the effect of reducing anxiety and agitation in patients, it also produced other problems such as apathy and decreased ability to show emotion. The surgery was used widely in the United States from the 1930s to the 1960s because there were no medications or other ways to treat patients who suffered from severe mental illness. Today the procedure is very rarely performed because there are many other well-accepted and less intrusive ways to study the brain. The use of electrodes, lesions, and the study of damaged brains after accidents are less invasive, less intrusive, and even more effective. electroencephalograph (EEG) a machine used to record the electrical activity of large portions of the brain 158 Electrodes are wires that can be inserted into the brain to record electrical activity in the brain. By inserting electrodes in the brain, it is possible to detect the minute electrical changes that occur when neurons fire. The wires are connected to electronic equipment that amplifies the tiny voltages produced by the firing neurons. Even single neurons can be monitored. The electrical activity of whole areas of the brain can be recorded with an electroencephalograph (EEG). Wires from the EEG are attached to the scalp so that millions upon millions of neurons can be monitored at the same time. Psychologists have observed that the overall electrical activity of the brain rises and falls rhythmically and that the pattern of the rhythm depends on whether a person is awake, drowsy, or asleep. These rhythms, or brain waves, occur because the neurons in the brain tend to increase or decrease their amount of activity in unison. Electrodes may be used to set off the firing of neurons as well as to record it. Brain surgeon Wilder Penfield stimulated the brains of his patients during surgery to determine what functions the various parts of the brain perform. In this way he could localize the malfunctioning part for which surgery was required, for example, for epilepsy. Phanie/SuperStock Electrodes When Penfield applied a tiny electric current to points on the temporal lobe of the brain, he could trigger whole memory sequences, including sound, movement, and color, that were clearer than usual memories. During surgery, one woman heard a familiar song so distinctly that she thought a recording was being played. Penfield discovered that by stimulating the same area of the brain again the same memory would be triggered. One benefit of using electrodes is that scientists can map the parts of the brain where different cognitive activities take place. A drawback is that it cannot be used during everyday activities because the subject needs to be hooked up to the electrodes. Profiles in Psychology Lesions Scientists sometimes create lesions by cutting or destroying part of an animal’s brain. If the animal behaves differently after the operation, they assume that the destroyed brain area is involved with that type of behavior. For example, in one classic lesion study, two researchers removed a certain area of the temporal lobe from rhesus monkeys. Normally, these animals are fearful, aggressive, and vicious, but after the operation, they became less fearful and at the same time less violent. The implication was that this area of the brain controlled aggression. The relations revealed by this type of research are far more subtle and complex than people first believed. For this reason it is hard to apply the findings from animal studies to the working of the human brain. Keystone/Hulton Archive/Getty Images Accidents Accidents that resulted in brain injuries, while tragic, offered insight into how the brain functions. Psychologists try to draw a connection between the damaged parts of the brain and a person’s behavior. One such case involved an unusual accident in 1848. Phineas Gage was a respected railroad foreman who demonstrated restraint, good judgment, and the ability to work well with other men. His crew of men was about to explode some dynamite to clear a path for the railroad rails. As Gage filled a narrow hole with dynamite and tamped it down, it suddenly exploded. The tamping iron had caused a spark that ignited the dynamite. The tamping iron, which weighed over 13 pounds and was over 3 feet in length, shot into the air! It entered Gage’s head right below the left eye, and it exited through the top of his skull. Gage survived the accident, but his personality changed greatly. He became short-tempered, was difficult to be around, and often said inappropriate things. Gage lived for several years after the accident. In 1994 psychologists Hanna and Antonio Damasio examined Gage’s skull using the newest methods available. They reported that the tamping iron had caused damage to parts of the frontal cortex. They found that damage to the frontal lobes prevents censoring of thoughts and ideas. In 2001 scans of Gage’s skull were made but later lost. In 2012 neuroscientists rediscovered the data and reconstructed the scans. They created a composite image of a brain using scans of several men physically similar to Gage and used imaging software to position the virtual brain within the virtual skull. Then they traced the trajectory of the tamping iron through the skull and brain and were able to identify what areas of the brain had been affected by the accident. These neuroscientists found that while the frontal cortex indeed had been directly damaged by the iron, perhaps more important was the destruction of more than 10 percent of the white matter in Gage’s brain. The significant loss of white matter connectivity is similar to the damage created by Alzheimer’s disease or frontal lobe dementia and probably played an even greater role in his personality change. Roger Wolcott Sperry 1913–1994 Roger Sperry first became well known in the specialized area of developmental neurobiology. He devised experiments that helped establish the means by which nerve cells become wired in particular ways in the central nervous system. Sperry is probably best known for his pioneering split-brain research. In the 1950s and 1960s, Sperry devised a number of experiments to test the functions of each hemisphere of the brain. He argued that two separate hemispheres of consciousness could exist under one skull. Sperry pioneered the behavioral investigation of split-brain animals and humans. His experiments and techniques laid the groundwork for constructing a map of mental functions. In 1981 he became co-recipient of the Nobel Prize for Physiology and Medicine for his investigations of brain functions. CRITICAL THINKING Interpreting Significance What are the behavioral implications of split-brain research? Body and Behavior 159 computerized axial tomography (CT) an imaging technique used to study the brain to pinpoint injuries and brain deterioration positron emission tomography (PET) an imaging technique used to see which brain areas are being activated while performing tasks Another unusual case took place in the nineteenth century. Dr. Paul Broca had a young patient who could only respond with hand gestures and the word “tan.” Broca theorized that a part of the brain on the left side was destroyed, limiting the young man’s communication processes. Many years later, researchers examined the young man’s brain using modern methods. They discovered that Dr. Broca’s theory was correct. The left side of the cortex, which is involved with the production of speech, was damaged. This area of the cortex is now known as Broca’s area. Another kind of brain damage, called Wernicke aphasia, occurs from damage of the temporal lobe. When this part of the brain is damaged, patients have trouble understanding spoken language. In addition, any sounds, phrases, or sentences that they try to speak themselves are not discernable. As a result of studying people with this type of damage, scientists can deduce that this part of the temporal lobe is associated with speech and language comprehension. Studying people who have suffered accidents to the brain is a very useful way to figure out which parts of the brain affect our different behaviors. This gives us ideas about the structure of the brain, but there are still many things to learn about the function of the brain and how these areas might be repaired after they have been damaged. Connecting Psychology to Geography 160 Many less developed countries are increasing or hope to increase funding for education on proper prenatal care and nutrition. CRITICAL THINKING 1. Assessing What birth defects are the result of maternal nutritional deficiencies? Why is education on this topic of such importance for mothers in all parts of the world? 2. Identifying Central Issues How does maternal nutrition affect fetal health and brain development? Benedicte Desrus/Sipa Press/Newscom GLOBAL NUTRITION AND BRAIN DEVELOPMENT Scientists have discovered that the health of a developing fetus is dependent largely on the diet and nutrition of the mother. For example, nutritional deficiencies during critical times of development can cause birth defects such as spina bifida and neural tube defects. Folic acid is needed early in pregnancy to reduce the chances of these abnormalities. This nutrient is found in leafy green vegetables, beans, nuts, grains, and citrus juices. A nutritious diet throughout the course of a woman’s pregnancy is more likely to produce a fetus with a normally developing brain and organs. This will produce a healthy fetus as well as increase the baby’s chance of survival after birth. There are areas of the world, however, where obtaining proper nutrition can be difficult. Women in many less developed countries or remote areas do not have access to enough of the nutritious foods needed to develop a healthy fetus. For instance, remote areas of Africa, lack foods rich in nutrients such as vitamin A, iodine, and iron. Vitamin A has been linked to a vulnerability to malaria, a significant public health problem in Africa. Iodine deficiency is the largest preventable cause of developmental disabilities but can be successfully remedied if treated during the first six months of pregnancy. An iron deficiency, also termed anemia, is associated with low birth weights. Continuing to provide education about a balanced diet and increasing access to proper nutrition, both so important to the health of the mother and the brain development of the fetus, is crucial. Disorders Some disorders give us interesting information about the brain. For example, synesthesia is a disorder in which senses become confused and are given the impression of being other senses. For example, a person may see a number and associate it with a color. The number four may give the impression of being green every time it is seen. A song may produce a sense of smell for someone. With a disorder called prosopagnosia, a person cannot recognize familiar faces. They may see a relative or close friend many times, and never develop a sense of familiarity and recognition when that person is seen. Studying these disorders can give psychologists clues about how people create associations as they recognize or experience things such as objects, colors, or faces. In addition to sensory disorders, the brain may also suffer degenerative disorders, or disorders that get worse over time. With Alzheimer’s disease, the decline in memory and cognitive abilities is due to neural connections in the cerebral cortex. With Parkinson’s disease, there is a decline of neural connections in the area of the brain associated with movement. When a person suffers a stroke, the flow of blood to the brain is disrupted, or there is bleeding within the brain. This may cause problems with muscular coordination or paralysis on one or both sides of the body. A study of degenerative diseases can show scientists how the brain ages and what effect changing neural connections may have on behavior. Images Dr. Paul Broca uncovered the connection between the brain and speech. Researchers proved Dr. Broca’s theory using PET scans. Today psychologists and medical researchers are using this and other sophisticated techniques, including CT scans and fMRI scans. In the 1970s, computerized axial tomography (CT) scans were used to pinpoint injuries and other problems in brain deterioration. During a CT scan, a moving ring passes X-ray beams around and through a subject’s head. Radiation is absorbed in different amounts depending on the density of the brain tissue. Computers measure the amount of radiation absorbed and transform this information into a three-dimensional view of the brain. More About... Nervous System Plasticity Today, researchers are beginning to recognize that neurons have a natural plasticity that causes constant changes in connections in reaction to new information, development, or sensory stimulation, and not just to recover from damage. As a young brain grows, new synaptic connections are made to respond to new stimuli. Through practice and use, some connections become stronger, and others may become weaker. Old connections may eventually be eliminated. As the brain ages, it changes to respond to new information and experiences, but it also begins a cognitive decline. Learning a new language or taking part in an activity that stimulates the brain’s functioning can help to create new connections and keep the brain’s plasticity working. DIAGRAM BRAIN ACTIVITY ON A PET SCAN A computer transforms the different levels of absorption by neurons of radioactive solution into colors. Red and yellow indicate maximum activity of neurons, while blue and green indicate minimal activity. CRITICAL THINKING 1. Defending Why would psychologists use a PET scan? RH.11–12.7 2. Drawing Conclusions Why do you think hearing and reading occur in different parts of the brain? RH.11–12.7 Body and Behavior 161 Magnetic resonance imaging (MRI) studies the activities of the brain. CRITICAL THINKING Evaluating Why does an MRI of the brain give a more thorough picture than a CT or PET scan would give? magnetic resonance imaging (MRI) a measuring technique used to study brain structure and activity The positron emission tomography (PET) scan can capture a picture of the brain as different parts are being used. It involves injecting a slightly radioactive solution into the blood and then measuring the amount of radiation absorbed by blood cells. Active neurons absorb more radioactive solution than nonactive ones. Researchers use the PET scan to see which areas are being activated while performing a task. PET scans show activity in different areas of the brain when a person is thinking, speaking, and looking at objects. The scan changes when one is talking and when one is looking at a piece of art. These pictures change as the activity changes. Another process, magnetic resonance imaging, or MRI, enables researchers to study both activity and brain structures. It combines the features of both CT and PET scans. It involves passing nonharmful radio frequencies through the brain. A computer measures how these signals interact with brain cells and translates these signals into a detailed image of the brain. Researchers use MRIs to study the structure of the brain as well as to identify tumors or types of brain damage. Researchers use a new technique of imaging, functional magnetic resonance imaging (fMRI), to directly observe both the functions of different structures of the brain and which structures participate in specific functions. The fMRI provides high-resolution reports of neural activity based on signals that are determined by blood oxygen level. The fMRI actually detects an increase in blood flow to the active structure of the brain. So, unlike the MRI, the fMRI does not require passing radio frequencies through the brain. With this new method of imaging, researchers have confirmed their hypotheses concerning the functions of areas such as the visual cortex, the motor cortex, and Broca’s area of speech- and language-related activities. READING PROGRESS CHECK Making Connections What might scientists learn by studying images of the brain? Reviewing Vocabulary Answering the Guiding Questions 1. Defining List and describe the main functions of the lobes of the human brain. RH.11–12.4 4. Describing What are the three parts of the human brain? What are the specializations of the left and right hemispheres of the brain? 2. Identifying What are the functions of the thalamus and the hypothalamus? RH.11–12.4 5. Explaining How can accidents that damage the brain instruct us in its functions? Using Your Notes Writing Activity 3. Diagramming Using the notes you took during this lesson, write a paragraph explaining how damage to each of the three parts of the brain might affect activities of daily life. WHST.11–12.9 6. Informative/Explanatory A woman severely injured the right hemisphere of her brain. Write a scenario in which you describe two body functions that might be affected by the woman’s injury. WHST.11–12.2 162 Paul Burns/Blend Images/Corbis LESSON 2 REVIEW on research Case Study One Person . . . Two Brains? Period of Study: 1979 Introduction: Victoria had experienced intense epi- Method: Researchers asked Victoria to stare at a leptic seizures since she was six years old. Doctors placed Victoria on medication that prevented seizures; however, after many years, the seizures returned with greater intensity. Weary and disgusted from living her life with the uncontrollable seizures, Victoria decided it was time to seek a new treatment. Doctors suggested and Victoria opted for a split-brain operation. This involved separating the two brain hemispheres by cutting the corpus callosum. Split-brain operations disrupt the major pathway between the brain hemispheres but leave each hemisphere functioning almost completely independently. The procedure prevents the spread of seizures from one hemisphere to the other and reduces the incidence or shortens the duration. The operation might result in other difficulties for Victoria, however. Researchers working with earlier patients who had undergone the procedure found that sometimes those patients acted as if they had a different personality in each hemisphere after the operation. One neuroscientist wrote: black dot between the letters HE and ART. The information from each side of the black dot would be interpreted by the opposite hemisphere in Victoria’s split brain. Victoria’s right hemisphere would “see” HE and her left would only “see” ART. When Victoria was asked what she had seen, she reported to have seen the word ART. The word ART was projected to her left hemisphere, which contains the ability for speech. She did indeed see the word HE; however, the right hemisphere could not make Victoria say what she had seen. With her left hand, though, Victoria could point to a picture of a man, or HE. This indicated that her right hemisphere could understand the meaning of HE. PRIMARY SOURCE (l)Phanie/SuperStock; (r)David Mack/Photo Researchers, Inc. patient] would sometimes find himself pulling his pants down “[The with one hand and pulling them up with the other. Once, he grabbed his wife with his left hand and shook her violently, with the right hand trying to come to his wife’s aid in bringing the left belligerent hand under control. ” —Michael Gazzaniga, The Bisected Brain (1970) Hypothesis: Researchers wanted to explore the degree to which the two halves of the brain could communicate and function on their own after the operation. Results: After some initial frustrations, Victoria developed new routines for everyday functions such as dressing, eating, and walking. Four months after her operation, she could easily remember and speak of past and present events in her life. Her reading, writing, and reasoning abilities were intact. Although the effects of her operation became apparent under special testing, they were not usually apparent in everyday life. Victoria, now free of her once-feared seizures, could live her life in full; split-brained but fundamentally unchanged. Analyzing the Case Study 1. Explaining Why did Victoria choose to have a split-brain operation? What did the operation involve? RH.11–12.3 2. Identifying What questions did researchers set out to answer after Victoria’s operation? RH.11–12.3 3. Applying Consider the quote from Gazzaniga. What problems do you think Victoria might encounter in everyday life? RH.11–12.2; RH.11–12.3 Body and Behavior 163 netw rks There’s More Online! DIAGRAM The Endocrine System IMAGE Firefighter SELF-CHECK QUIZ LESSON 3 The Endocrine System Academic Vocabulary ESSENTIAL QUESTION • How do changes in our bodies’ processes lead • beneficial • impact to changes in our behavior? Content Vocabulary • endocrine system • hormones • pituitary gland TAKING NOTES: Key Ideas and Details CATEGORIZING Use a graphic organizer like the one below to list four types of glands in the endocrine system. It Matters Because The endocrine system controls and excites growth in the body and affects our emotions and behaviors. Hormones secreted by the endocrine system can cause the body to react and become very active. Understanding functions such as these “adrenaline rushes” help us understand how and why body processes can affect our behavior. The Endocrine Glands GUIDING QUESTION What is the function of the pituitary gland? The nervous system is one of two communication systems for sending information to and from the brain. The second is the endocrine system. The endocrine system sends chemical messages, called hormones. The hormones are produced in the endocrine glands and are distributed by the blood and other body fluids. Hormones circulate throughout the bloodstream but are properly received only at a specific site: the particular organ of the body that they influence. The endocrine glands are also called ductless glands because they release hormones directly into the bloodstream. In contrast, the duct glands release their contents through small holes, or ducts, onto the surface of the body or into the digestive system. Examples of duct glands are sweat glands, tear glands, and salivary glands. Hormones have various effects on your behavior. They affect the growth of bodily structures such as muscles and bones, so they affect what you can do physically. Hormones affect your metabolic processes; that is, they can affect how much energy you have to perform actions. Certain hormones are secreted during stressful situations to prepare the body for action. Hormones also act in the brain to directly influence your moods and drives. Some hormonal effects take place before you are born. Essentially all the physical differences between boys and girls are caused by a hormone called testosterone. Scientists have developed a synthetic steroid hormone that resembles testosterone. This drug can be beneficial, as it promotes muscle growth when it is taken as a drug. Steroids are used to treat weight loss caused by 164 Mike Kemp/age fotostock Reading HELPDESK DESK some diseases. It is also used illegally by some athletes to enhance their physical performance. However, there are several endocrine glands throughout the body that produce hormones naturally. Pituitary and Thyroid Glands Directed by the hypothalamus, the pituitary gland acts as the master gland. Located near the midbrain and the hypothalamus, the pituitary gland secretes a large number of hormones, many of which control the output of hormones by other endocrine glands. The hypothalamus monitors the amount of hormones in the blood and sends out messages to correct imbalances. What do these hormone messages tell the body to do? They carry messages to organs involved in regulating and storing nutrients so that despite changes in conditions outside the body, cell metabolism can continue on an even course. They also control growth and reproduction, including ovulation and lactation (milk production) in females. The pituitary gland is about the size of a pea and weighs only half of a gram. The thyroid gland is one of the largest endocrine glands in the human body. It is located in the neck and is separated into two lobes. The glands can be felt on either side of the neck below the jaw. The thyroid controls how quickly the body uses energy and makes proteins. It produces the hormone thyroxine. Thyroxine stimulates certain chemical reactions that are important for all tissues of the body. Too little thyroxine makes people feel lazy and lethargic—a condition known as hypothyroidism. Too much thyroxine may cause people to lose weight and sleep and to be overactive—a condition known as hyperthyroidism. Adrenal Glands The adrenal glands are located on top of the kidneys, one on each side of the body. They become active when a person is angry or frightened. Neural responses from the adrenal glands originate near the spinal column. Each adrenal gland consists of a medulla (the center of the gland), surrounded by a cortex. The adrenal medulla is responsible for producing epinephrine and norepinephrine (also called adrenaline and noradrenaline). When released into the bloodstream, these secretions cause the heartbeat and breathing to increase. They can heighten emotions, such as fear and anxiety. These and other changes help a person generate the extra energy he or she needs to handle a difficult situation. Most of the responses that our bodies have to stress, fear, anger, and other emotional reactions are controlled by the adrenal glands. The adrenal glands also regulate salt and water levels in the body and help regulate the body’s metabolic processes. The adrenal cortex produces cortical steroids, which help regulate blood pressure, inflammation, and the body’s immune response. They have an impact on the body’s use of fats, proteins, and carbohydrates. Psychology & You Do You Do This? Human ethology is the study of human behavior as it naturally occurs. Basketball fans know that Michael Jordan stuck out his tongue when he attempted a difficult shot. Similarly, it has been found that expert billiard players stick out their tongues more often when making hard shots than when attempting relatively easy shots. According to ethologists, a tongue display acts as a nonverbal sign that interaction is not desired. For humans, the tongue displays seem to indicate that the person does not want to be interrupted because of the need to concentrate in a difficult situation. endocrine system a chemical communication system, using hormones, by which messages are sent through the bloodstream hormones chemical substances that carry messages through the body in blood beneficial having a helpful or useful effect Sex Glands pituitary gland the center of There are two types of sex glands—testes in males and ovaries in females. Testes produce sperm and the male sex hormone testosterone. Even though they do not have testes, low levels of testosterone are also found in females. Ovaries produce eggs and the female hormones estrogen and progesterone, although, just as with the testosterone hormone in females, low levels of estrogen and progesterone are also found in males. Testosterone is important in the physical development of males, especially in the prenatal period and in adolescence. In the prenatal period, testosterone helps decide the sex of a developing fetus. In adolescence, testosterone is important for the growth of muscle tissue and bones along with the growth of secondary male sexual characteristics. In adulthood, testosterone helps to keep muscle tissue and bones strong and to maintain an interest in sex. control of the endocrine system that secretes a large number of hormones impact to have a direct effect upon something Body and Behavior 165 DIAGRAM THE ENDOCRINE SYSTEM The endocrine system, which consists of ductless glands and the hormones they produce, works closely with the nervous system in regulating body functions. CRITICAL THINKING 1. Analyzing Visuals What is the function of the adrenal glands? 2. Gathering Information Which part of the endocrine system controls metabolic rate? After the age of 30 a man’s testosterone levels gradually begin to decrease. Low levels of testosterone can lead to fatigue, weakness, depression, and low sex drive. Even when these symptoms are not present, men are encouraged to seek treatment because a low level of testosterone can often lead to a decrease in bone density, making bones more fragile and prone to breaking. Estrogen and progesterone are important in the development of female sex characteristics. These two hormones also regulate the reproductive cycle of females. The levels of estrogen and progesterone vary throughout the menstrual cycle. These variances can cause premenstrual syndrome, also commonly known as PMS, in some women. PMS can include such symptoms as abdominal pain, headaches, fatigue, irritability, and depression. The change of hormone levels during and after pregnancy can also lead to postpartum depression in a small percentage of women. This depression is characterized by trouble sleeping, anxiety, changes in appetite, or loss of concentration. More serious symptoms include thoughts of death or suicide, or negative feelings toward the baby. Women with postpartum depression should seek help from a doctor. The symptoms usually develop shortly after the birth of the child but can occur up to a year afterwards. Postpartum depression can be treated with medications. READING PROGRESS CHECK Locating Where do endocrine glands release hormones in the body? 166 Hormones vs. Neurotransmitters GUIDING QUESTION What is the difference between a hormone and a neurotransmitter? Both hormones and neurotransmitters work to affect the nervous system. In fact, the same chemical can be used as both a hormone and a neurotransmitter. So what is the difference between a hormone and a neurotransmitter? When a chemical is used as a neurotransmitter, it is released right beside the cell that it is to excite or inhibit. When a chemical is used as a hormone, it is released into the blood, which diffuses it throughout the body. For example, norepinephrine is a hormone when it is secreted into the blood by the adrenal glands. It is a neurotransmitter when it is released by the sympathetic motor neurons of the peripheral nervous system. Hormones and neurotransmitters appear to have a common evolutionary origin. As multicellular organisms evolved, the system of communication among cells coordinated actions so that all cells of the organism acted as a unit. As organisms grew more complex, this communication system began to split into two more specialized communication systems: the nervous system, developed to send rapid and specific messages, and the other, involving the circulatory system, developed to send slow and widespread communication. In this system, the chemical messengers evolved into hormones. Whereas neural messages can be measured in thousandths of a second, hormonal messages may take minutes to reach their destination and weeks or months to have their total effect. Hormones and neurotransmitters work together in our bodies, and can even compete with each other. For example, neurotransmitters may become out of balance due to stress, poor diet, or a genetic predisposition. This, in turn, causes hormonal imbalances. Mood swings, lack of energy, and even depression can result. Similarly, the hormones released by the thyroid may become imbalanced and affect the work of neurotransmitters in the body. Medications can be used to regulate the balance between hormones and neurotransmitters when the body is not functioning properly. Some medications use hormones such as estrogen or progesterone. The levels of hormones and neurotransmitters in our bodies control everything from our emotions to our physical growth and bodily functions. In the event of a life-threatening or highly stressful situation, the adrenal glands produce adrenaline to give people the necessary energy to cope. CRITICAL THINKING Drawing Conclusions How does adrenaline affect emotions? READING PROGRESS CHECK Comparing and Contrasting How does the speed of neural messages differ from the speed of chemical messages? LESSON 3 REVIEW Reviewing Vocabulary Answering the Guiding Questions 1. Defining What are three ways that the endocrine system affects behavior? 3. Expressing What is the function of the pituitary gland? Mike Kemp/age fotostock Using Your Notes 2. Applying Using the notes you took during this lesson, write a paragraph explaining the function of hormones that are produced by the glands of the endocrine system. 4. Explaining What is the difference between a hormone and a neurotransmitter? Writing Activity 5. Informative/Explanatory Write a description of a medical situation in which a psychologist would examine the thyroid gland. Describe the situation from the perspective of a patient. Body and Behavior 167 Analyzing Readings in Psychology Reader’s Dictionary Genetically Programmed to Be Nice? maternal characteristic of a mother prosocial acting for the benefit of others endeavor a serious effort or attempt Childhood Trauma and Depression By APS Observer PRIMARY SOURCE Childhood is supposed to be a happy, carefree time, and for most of us, it is. But for over one million children a year in the United States alone, this period will be marred by trauma. A wide spectrum of later disorders and symptoms have been linked to early-life stress and abuse, including cardiovascular disease, fibromyalgia, fatigue, anxiety, and addiction. However, one of the most common consequences of having suffered trauma as a child is a higher risk in adulthood of developing depression, a psychiatric disorder that is debilitating, and in many cases, fatal. At the APS 22nd Annual Convention, Emory University’s Christine Heim presented a wealth of research documenting how childhood trauma can cause depression later in life. Although stress is something we believe we go “through” and survive relatively unscathed, it appears that stressful events, such as the death of a parent, physical abuse or sexual abuse, particularly experienced early in life, causes multiple changes in the central nervous system that result in 168 Studies continue to demonstrate that personality, behavior, and development can be affected by many things, including genetics, hormones, and life events. The body can affect the mind, and vice versa. The studies in these two articles indicate that we can be influenced both by nature (genetics) and nurture (environmental factors). physiological and behavioral changes. Early-life stress appears to radically alter neurobiological systems involved in the pathophysiology of depression. On the basis of extensive endocrine, brain imaging, genetic, and behavioral analyses, Heim showed a clear link between childhood trauma, altered gene regulation, increased levels of stress hormones, and changes in brain structure. Changes resulting from stress included a smaller hippocampus, disruption of cortisol regulation and increased corticotrophin releasing factor. These effects add up to a shift in the body’s fundamental stress-coping mechanisms, particularly the hypothalamic-pituitary-adrenal axis, causing behavioral changes. In plain English, suffering stress early in life makes us more vulnerable to stress later in life. The evidence for this can be seen in multiple physiological and behavioral changes: in blood pressure, heart rate, and blood glucose levels, as well as disrupted sleep cycles, eating patterns, and fear conditioning. Far from being transient, stress experienced early in life has longterm and damaging effects on the entire body. According to Heim, there is more than one type of depression. Specifically, depression that developed in relation to early life stress seems to have a distinct biological profile compared to depression that is not related to early-life stress. These groups of patients also do not respond to the same treatment, and Heim suggests that in order to successfully treat them, therapies can be tailored to restore the pathways involved in each subtype. PHOTO: Sean Locke/the Agency Collection/Getty Images; TEXT: APS observer by AMERICAN PSYCHOLOGICAL SOCIETY Copyright 2010 Reproduced with permission of ASSOCIATION FOR PSYCHOLOGICAL SCIENCE in the format Republish in “other” book via Copyright Clearance Center. Republished with permission of ASSOCIATION FOR PSYCHOLOGICAL SCIENCE from Childhood Trauma and Depression, APS observer Vol. 23, No. 6, July/August 2010; permission conveyed through Copyright Clearance Center, Inc. Childhood Trauma and Depression pathophysiology functional changes that occur with a disease or syndrome transient lasting only for a short time Genetically Programmed to Be Nice? by Rick Nauert, PhD PHOTO: Blickwinkel/age fotostock; TEXT: © 2012 Psych Central PRIMARY SOURCE Emerging research suggests that some people may be genetically endowed to be nice. Investigators from the University at Buffalo and the University of California, Irvine, discovered the genetic association for a trait that many assume is a product of how we are raised. “We aren’t saying we’ve found the niceness gene,” said researcher and psychologist Michael Poulin, PhD. ”But we have found a gene that makes a contribution. What I find so interesting is the fact that it only makes a contribution in the presence of certain feelings people have about the world around them.” The study, published in the journal Psychological Science, examines the behavior of subjects who have versions of receptor genes for two hormones that, in laboratory and close relationship research, are associated with niceness. Previous laboratory studies have linked the hormones oxytocin and vasopressin to the way we treat one another, said Poulin. Psychologists believe the hormones make us nicer people, at least in close relationships. Oxytocin promotes maternal behavior, for example, and in the lab, subjects exposed to the hormone demonstrate greater sociability. Poulin said the current study was an attempt to apply previous findings to social behaviors on a larger scale; to learn if these chemicals provoke in us other forms of prosocial behavior. Examples could be the urge to give to charity, or to more readily participate in such civic endeavors as paying taxes, reporting crime, giving blood or sitting on juries. Scientists say that hormones work by binding to cells through receptors that come in different forms. In that regard, there are several genes that control the function of oxytocin and vasopressin receptors. Subjects were surveyed as to their attitudes toward civic duty, other people and the world in general, and about their charitable activities. Specifically, participants completed an Internet survey with questions about civic duty, such as whether people have a duty to report a crime or pay taxes; how they feel about the world, such as whether people are basically good or whether the world is more good than bad; and about their own charitable activities. Of those surveyed, 711 subjects provided a sample of saliva for DNA analysis, which showed what form they had of the oxytocin and vasopressin receptors. “The study found that these genes combined with people’s perceptions of the world as a more or less threatening place to predict generosity,” Poulin said. “Specifically, study participants who found the world threatening were less likely to help others— unless they had versions of the receptor genes that are generally associated with niceness,” he said. “These “nicer” versions of the genes,” said Poulin, “allow you to overcome feelings of the world being threatening and help other people in spite of those fears. “The fact that the genes predicted behavior only in combination with people’s experiences and feelings about the world isn’t surprising,” Poulin said, “because most connections between DNA and social behavior are complex. “So if one of your neighbors seems really generous, caring, civic-minded kind of person, while another seems more selfish, tight-fisted and not as interested in pitching in, their DNA may help explain why one of them is nicer than the other,” he said. Analyzing Primary Sources 1. Identifying Bias What is a possible source of bias in the second article? 2. Drawing Conclusions According to the first article, why should childhood history be probed before treating depression? 3. Comparing and Contrasting On a physiological level, how is the “niceness” trait different from adult-onset depression? Body and Behavior 169 netw rks There’s More Online! DIAGRAM DNA and Genes DIAGRAM Punnett Square IMAGE Fraternal and Identical Twins IMAGE Environmental Influence LESSON 4 SELF-CHECK QUIZ Heredity and Environment ESSENTIAL QUESTION • How do internal functions of the body affect behavior? Academic Vocabulary • modify • similar Content Vocabulary • heredity • genes • genotype • phenotype • inbred • outbred • identical twins • fraternal twins TAKING NOTES: Key Ideas and Details GATHERING INFORMATION Use a graphic organizer like the one below to find examples of nature and nurture. Nature 170 Nurture It Matters Because For decades, scientists have been trying to figure out how much of our behavior is the result of our genes and how much is a result of our environment. Some psychologists believe that genetics is like a flower, and the environment is like rain, soil, or fertilizer. Genes establish what you could be, and the environment defines the final product. Nature versus Nurture GUIDING QUESTIONS What is heredity? How does heredity affect behavior? People often argue about whether human behavior is instinctive (due to heredity) or learned (due to environment). Heredity is the genetic transmission of characteristics from parents to their offspring. Do people learn to be good athletes, or are they born that way? Do people learn to do well in school, or are they born academically gifted? Many people assume that something learned can probably be changed, whereas something inborn will be difficult or impossible to change. This issue, commonly called nature versus nurture, is not so simple. Nature refers to characteristics that a person inherits—his or her biological makeup. Nurture refers to environmental factors, such as education, family, culture, and individual experiences. Inherited factors and environmental conditions always act together in complicated ways. Asking whether heredity or environment is responsible for a person’s behavior is like asking, “What makes a cake rise, baking powder or heat?” Obviously, an interaction of the two is responsible. The argument over the nature versus nurture question has been going on for centuries, and it continues today. The British scientist Sir Francis Galton became one of the first to support the importance of nature in the modern era. In 1869 he published Hereditary Genius, a book in which he analyzed the families of over 1,000 eminent politicians, religious leaders, artists, and scholars. He found that success ran in families and concluded that heredity was the cause. Many psychologists, however, have emphasized the importance of the environment. The tone was set by John Watson, the founder of behaviorism, who wrote: (l)Barbara Penoyar/Photodisc/Getty Images; (c)Peter Mintz/First Light/Corbis Reading HELPDESK DESK heredity the genetic PRIMARY SOURCE me a dozen healthy infants, well-formed, and my own specified world to bring them up in and I’ll “Give guarantee to take any one at random and train him to become any type of specialist I might select—a transmission of characteristics from parents to their offspring doctor, lawyer, artist, merchant-chief, and, yes, even beggarman and thief, regardless of his talents, penchants, tendencies, abilities, vocations, and race of his ancestors. ” —John B. Watson, Behaviorism (1924) Genotypes and Phenotypes A large part of new research on heredity has focused on genes. Genes are the basic units of heredity. They are reproduced and passed along from parent to child. All the effects that genes have on behavior occur through their role in building and modifying the physical structures of the body. Those structures must interact with their environment to produce behavior. In the normal structure of human DNA there are a total of 46 chromosomes, or 23 pairs. Twenty-two of these pairs are autosomes, which determine many of the traits an individual will have. One pair of chromosomes determines the sex of the individual while also carrying some sex-specific traits. The X chromosome is found in both males and females. The Y chromosome is found only in males. So a chromosomal pair of XX would belong to a woman, and an XY pair would belong to a man. There are variations among this normal structure, which cause abnormalities within the individual. The sets of genes you have in your body are considered your genotype. They are the blueprint of a person’s genetic information. At the time of reproduction or cell division, this inherited information is passed from one generation to the next. This genetic code indicates an infinite amount of information about the organism. It might indicate the possible traits a person can have in terms of hair color, gender, height, weight, or any number of characteristics, both physical and behavioral. A person’s genotype may even make them predisposed to such conditions as heart disease, diabetes, Alzheimer’s disease, epilepsy, or cancer. genes the basic building blocks of heredity modify to change something slightly genotype the set of genes in an organism DIAGRAM DNA AND GENES The molecules of DNA make up chromosomes that contain the codes for our biological makeup. CRITICAL THINKING 1. Assessing What are genes? 2. Analyzing Visuals Where are the instructions for development located in a cell? Body and Behavior 171 Paternal b B BB Bb b Bb bb Maternal B DI AGRAM PUNNETT SQUARE Assign the letter to each box of the Punnett Square based on the corresponding gene from each parent. Dominant genes are listed first and mask recessive genes. CRITICAL THINKING 1. Calculating What is the likelihood of parents with a BB and bb combination having a blond child? 2. Analyzing Why can’t two blond parents have a brown-haired offspring? phenotype the expression of a particular trait in an organism inbred descended from ancestors with similar genetics outbred descended from ancestors with dissimilar genetics The outward expression of those genes is a person’s phenotype. A person’s phenotype is expressed in his or her cells, tissues, organs, reflexes, behaviors, and anything observable in the living organism. A person may have a genotype that does not express itself as a phenotype except under certain environmental conditions. For example, a gene for diabetes may not be expressed as an observable phenotype unless diet and other environmental factors come into play in the person’s life. Other genes, such as a person’s gender or eye color, are expressed and observable immediately at birth and remain as the person ages. Chromosomal Abnormalities There are also chromosomal abnormalities that can spontaneously occur in offspring. For example, Down syndrome is a result of an extra chromosome on the 21st chromosomal pair. As a result, the individual has 47 chromosomes instead of 46. British physician John Langdon Down was the first to notice the symptoms in patients in 1866. The abnormality is characterized by cognitive disabilities and delayed physical growth, as well as characteristic facial structure and physical features. Approximately one in every 740 births results in Down syndrome. Offspring from older mothers tend to have a higher incidence of Down syndrome—from 1 in 100 to 1 in 30 births, as opposed to the incidence of 1 in 1,000 births from younger mothers. Other abnormalities, such as sickle-cell anemia, cystic fibrosis, albinism, and many other conditions are also the result of chromosomal inheritance. In the early 1900s, biologist Reginald C. Punnett developed a method of predicting the likelihood of genotypes based on particular crossbreeding called a Punnett Square. With a Punnett Square, letters are assigned to certain attributes to indicate the dominant, or likely, trait and the recessive, or less likely, trait. For example, brown hair is a dominant trait indicated by a capital B. Blond hair is recessive, and indicated with a lowercase b. Each parent carries a genotype for hair type. A Punnett Square like the one shown in the diagram indicates the likelihood that those parents have an offspring with brown or blond hair. When a dominant gene is present in the genotype it masks the recessive one. When only recessive genes are present in the genotype, the recessive gene is reflected in the phenotype. So two brown-haired parents carrying a Bb genotype have a one in four chance of having a blond child. An inbred organism is one that comes from two parents with similar or shared genetic makeup. An outbred organism is one that comes from parents with unrelated genetic makeup. Heredity can be a contributing factor in the development of certain characteristics. Scientists have found that inbred organisms produce more predictable results in their offspring. However, inbreeding may also create undesirable combinations, such as harmful recessive genes carried by both parents. Outbreeding brings a more varied gene selection but makes the characteristics of the offspring less predictable. Scientists have been able to witness this in a controlled environment by comparing the differences between inbred and outbred animals such as rats and mice. They found that inbred mice had more predictable features and characteristics similar to their parents, but exhibited an increased number of abnormalities. The outbred animals exhibited less predictable characteristics but fewer abnormalities. READING PROGRESS CHECK Contrasting What is the difference between an individual’s genotype and his or her phenotype? 172 Twin Studies GUIDING QUESTION What can be learned about nature and nurture from twin studies? identical twins twins who come from one fertilized egg; twins having the same heredity fraternal twins twins who come from two different eggs fertilized by two different sperm similar alike but not exactly the same Fraternal twins come from two eggs and share no more genetic similarities than other siblings. Identical twins come from a single egg and share their genetic code. CRITICAL THINKING Assessing How would studies of identical and fraternal twins provide evidence in the nature–nurture debate? (l)Peter Mintz/First Light/Corbis; (r)Barbara Penoyar/Photodisc/Getty Images One way to find out whether a trait is inherited is to study twins. Identical twins develop from a single fertilized egg and share the same genes. Because they develop from a single fertilized egg (a single zygote), identical twins are called monozygotic. Fraternal twins develop from two fertilized eggs and their genes are not more similar than those of brothers or sisters. That is, since fraternal twins are from separate eggs, like brothers or sisters from single births, they share only fifty percent of their genes. Having developed from two fertilized eggs, fraternal twins are called dizygotic. Twin studies can tell us quite a bit about the impact of heredity and environment. Twins growing up in the same house share the same general environment, but identical twins also share the same genes. So, if identical twins who grow up together prove to be more alike on a specific trait than fraternal twins do, it probably means that heredity and genes are important for that trait. In addition to twin studies, psychologists have found it helpful to study full siblings who are not twins. The genes of the individuals being compared would be similar because they came from the same parents, but they would not be the same as individuals in an identical twin study. The ages of the individuals would also be different. However, the environments that the children grew up in would be considered similar. Most siblings who grow up in the same household have the same general life experiences and interact with many of the same people. Comparisons between these individuals would show how much their environmental upbringing might affect their decision-making, their social skills, or their likes or dislikes. Similarly, studies of adopted people also give psychologists clues about nature versus nurture. When studying an adopted sibling along with one that is an offspring of the parents, there may be clues about how much of an impact environment alone would have on a person’s behavioral traits. Comparing two siblings who grew up in the same household but have no genetic similarities can indicate exactly how much impact experience has on an individual. Body and Behavior 173 Some people may have a predisposition for being good swimmers, but if they are not exposed to the correct environment to develop the skill, they may not realize their genetic potential. CRITICAL THINKING Drawing Inferences How might a person’s environment make them more or less aware of their genetically determined skills? Psychologists at the University of Minnesota have been studying identical twins who were separated at birth and reared in different environments. One of the researchers, Thomas Bouchard, reports that despite very different social, cultural, and economic backgrounds, the twins shared many common behaviors. For example, in one set of twins (both named Jim), both had done well in math and poorly in spelling while in school, both worked as deputy sheriffs, vacationed in Florida, gave identical names to their children and pets, bit their fingernails, had identical smoking and drinking patterns, and liked mechanical drawing and carpentry. These similarities and others suggest that heredity may contribute to behaviors that we normally associate with experience. Many researchers now believe that many of the differences among people can be explained by considering heredity as well as experience. Contrary to popular belief, the influence of genes on behavior does not mean that nothing can be done to change the behavior. Although it is true that it is difficult and some believe undesirable for scientists to attempt to identify and change the genetic code that may direct certain behaviors, it is possible to alter the environment in which the genes operate. READING PROGRESS CHECK Explaining Why are scientists particularly interested in twins when studying heredity? LESSON 4 REVIEW Reviewing Vocabulary Answering the Guiding Questions 1. Defining Explain the difference between fraternal twins and identical twins. 3. Applying What is heredity? How does heredity affect behavior? 2. Hypothesizing Using the notes you took during this lesson, find an example of two characteristics, one that could be classified as a result of nature and one a result of nurture. Construct alternative explanations that could describe how the characteristic is actually a result of the opposite stimulus. 174 Writing Activity 5. Argument Research what evidence each side of the nature versus nurture argument uses to disprove the opposing viewpoint. Taking one side of the argument, write an opinion piece supporting your view and opposing the other. Erik Isakson/Tetra Images/Corbis Using Your Notes 4. Identifying What can be learned about nature and nurture from twin studies? CHAPTER 6 Assessment Directions: On a separate sheet of paper, answer the questions below. Make sure you read carefully and answer all parts of the question. Lesson Review 21st Century Skills Lesson 1 Creating and Using Graphs, Charts, Diagrams, and Tables Researchers have found that the brains of patients with Alzheimer’s disease have a large number of destroyed neurons in the part of the brain that is crucial for making memories permanent. These patients have also exhibited a loss of the neurotransmitter acetylcholine, resulting in memory difficulties. Review the graph and then answer the questions that follow. 1 Describing Explain how messages travel to and from the brain through the nervous system. 2 Identifying What part of the brain controls voluntary activities? Lesson 2 3 Applying Describe four methods used to study the brain. 4 Summarizing Which part of the brain controls the movements of the right side of the body? 16 13.2 Lesson 3 Expressing How are messages of the endocrine system transmitted throughout the body? 6 Specifying Which gland in the body is the master control of hormone output by the endocrine system? 12 PEOPLE (IN MILLIONS) 5 Lesson 4 7 8 Expressing One way to find out whether a trait is inherited is to compare the behavior of identical and fraternal twins. Explain how this works. 4 4.5 Specifying What chromosomal abnormality causes Down syndrome? 0 2000 Research and Technology 9 8 Researching Brain plasticity is the capacity of the brain to change with learning. Just as physical exercise improves physical fitness, exercising one’s brain results in better mental fitness. Research the topic of “brain fitness” and, as a class or within groups, use software to write and design a brain fitness activity for the Web. Track changes and review each other’s work. If you can’t post to the Web, present the “site” as a storyboard or as PowerPoint slides. Explain to the viewer what specific cognitive skill(s) or improvement the activity is meant to achieve and which area(s) of the brain will most likely be affected. ‘10 ‘20 ‘30 ‘40 2050 YEAR (PROJECTION) 10 According to the graph, how many people in the United States suffer from Alzheimer’s disease? 11 How would you describe the projected number of cases of Alzheimer’s by the year 2050? 12 What impact might the researchers’ findings and the information in the graph have on the direction researchers might take to find a cure for the disease? Need Extra Help? If You’ve Missed Question Go to page 1 2 3 4 5 6 7 8 9 10 11 12 149 149 158 155 164 165 172 173 157 157 157 157 Body and Behavior 175 CHAPTER 6 Assessment Directions: On a separate sheet of paper, answer the questions below. Make sure you read carefully and answer all parts of the question. Critical Thinking Questions Exploring the Essential Questions Analyzing How would people’s lives be different if the nervous system were not made of the somatic and the autonomic nervous systems? What if people had only a somatic nervous system? 14 Synthesizing Suppose a person suffers a stroke that causes damage to the frontal lobes. What aspects of the person’s behavior would you expect to see change? 15 Exploring Issues Provide an example of how the physiological reaction created by adrenaline is helpful in emergency situations. 16 Interpreting Significance Do you think it is important for parents who wish to adopt a child to find out about the genetic makeup of the child? Why or why not? 17 Making Connections Which aspects of your personality, your way of acting, and your appearance seem obviously the result of heredity? Which seem to be more related to your environmental upbringing? Which characteristics are definitely the result of an interaction between heredity and environment? 18 20 Examining Working with two or three classmates, prepare a video that can be used to teach younger children how the brain and the nervous system work. You might consider making the video humorous to more easily gain the attention of younger children. Arrange to have children in lower grades view the video. Evaluate its effectiveness. 21 Applying Find out about problems that occur as a result of the malfunctioning of parts of the endocrine system. Find out how such problems are treated and present your findings in an oral report. Analyzing Primary Sources Use the document below to answer the following questions. PRIMARY SOURCE words, each hemisphere [of the brain] seems to have its “Inownother separate and private sensations; its own perceptions; its own concepts; and its own impulses to act. . . . Following surgery, each hemisphere also has thereafter its own separate chain of memories that are rendered inaccessible to the recall processes of the other. ” Diagramming Draw a Punnett Square to show the possible results of two inbred mice with pure recessive genes for tail length (tt/tt). Then draw a Punnett Square to show the possible results of two outbred mice. One has dominant genes for a long tail (Tt) and the other has recessive genes for a short tail (tt). —Roger Wolcott Sperry 22 Specifying What evidence does Roger Wolcott Sperry give that shows that observing brain activity after split-brain surgery can help us understand behavior? 23 Discussing How might a discovery like the one described help the research processes of other scientists? College and Career Readiness 19 Research and Methods Contact a radiologist or the radiology department of a local hospital to find out more about the uses of CT scans, PET scans, and fMRIs. Find out under what circumstances each of the techniques would be used. Present your findings in a written report. Psychology Journal Activity 24 Informative/Explanatory Review your entry in your Psychology Journal for this chapter. After learning about the nervous system, how would you explain the connection between mind and body? List some examples of how this connection appears in everyday life. Need Extra Help? If You’ve Missed Question Go to page 176 13 14 15 16 17 18 19 20 21 22 23 24 149 154 167 172 170 172 161 148 164 156 156 146 TEXT: Copyright © 1968, American Psychological Association 13
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