SOUTHERN CALIFORNIA UNIVERSITY OF HEALTH SCIENCES
COLLEGE OF SCIENCE AND INTEGRATIVE HEALTH
DEPARTMENT OF PROFESSIONAL STUDIES
INSTITUTE OF SCIENCE
COURSE INFORMATION
Course Title:
Organic Chemistry I - LECTURE
Course Number(s):
OCHM311
Term:
SP2016
Time Requirement: (hours/week)
Lecture Hours: 45
Total Units: 3
Prerequisites: High School Diploma or equivalent; General Chemistry I and II or equivalents.
Faculty:
Lead Faculty: Mr. Justin Dreyfuss
Contact Information: [email protected]
Office Hours: TBD
COURSE PURPOSE
Course Description: The course will begin with a review of some of the major concepts in organic
chemistry. The chemistry of carbon compounds will be distinguished from inorganic chemistry. The various
classes of aliphatic and aromatic compounds will be examined. The diversity of functional groups will be
explored with regard to reactivity and mechanism. Nucleophilic and electrophilic reaction mechanisms will
be stressed. Stereochemistry will be explored. Concepts of hydrophobicity and hydrophilicity will be
examined in relation to extraction, phase partitioning, absorption and chromatography. Biochemical and
physiological analogies will be reviewed.
University Learning Outcomes:
1. Evidence-Based Knowledge: The student will utilize foundational health science knowledge; and
critically appraise and apply relevant scientific literature in professional healthcare practice.
2. Communication: The student will effectively engage patients/clients, colleagues, and the public
using appropriate verbal, non-verbal, and written communication.
3. Professionalism: The student will demonstrate leadership, integrity, respect, and self-reflection
while employing ethical and legal standards in professional and community interactions.
4. Integrative Healthcare: The student will serve as an effective member of a healthcare team,
collaborating with other professionals to improve community health and patient outcomes for
the health of individuals and the community.
Organic Chemistry I Program Learning Outcomes:
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1. Basic Science Knowledge: The course focuses on the basic principles that govern the structure
and reaactivity of organic molecules, standard organic reactions, and also introduces the
common functional groups.
2. Scientific Reasoning: Students are introduced explicitly to the Scientific Method. The class
exposes them to identifying and analyzing components of a chemical reaction and how to predict
reaction mechanisms given reactants and conditions all of which are necessary to be able to test and
investigate scientific claims.
3. Information Literacy: Textbook reading is assigned and students are required to do a lot of
independent learning. By asking questions on readings and outside learning to professors and
peers, students will gain more knowledge on how to find and assimilate important information
from sources.
4. Communication Effectiveness: Through the utilization of in class discussions, lab reports, online
discussion board posts and responses, students will learn how to share ideas and give
constructive criticisms. Peer and professor critiques will help students grow to become more
effective collaborators and communicators.
Course Objectives:
The general objective of this course is to prepare students for future courses involving chemical
reactions. Students will be introduced to synthetic laboratory techniques and equipped with an
understanding of the language of organic chemistry, with the goal of gaining intuition for electron flow.
At the conclusion of this course, a successful student should be able to:
1. Recognize and utilize IUPAC nomenclature for simple organic molecules.
2. Analyze conformations of linear and cyclic molecules.
3. Discuss stereochemistry and its relevance in the medical field.
4. Identify the components of a chemical reaction and describe mechanisms for simple organic
reactions.
5. Predict reaction mechanisms given reactants and conditions.
6. Comprehend regioselectivity and stereoselectivity, and their relevance in synthesis.
7. Develop a vocabulary of reaction mechanisms and comprehend their strategic use.
INSTRUCTIONAL MATERIALS
Required Text(s):
Organic Chemistry, 8th Ed., by Wade, Jr. (ISBN: 13: 9780321768148)
Required Materials:
Provided Materials:
Required Attire:
Students are required to wear closed-toed shoes.
Classroom Expectations:
• Please be professional, prompt, prepared, and polite at all times.
• The professor will adhere to all polices as found in the Student Handbook
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•
•
Cellular phones must be kept on silent during class and lab times.
Students may not use a phone as a calculator.
TEACHING METHODS AND ACTIVITIES
There are 9 hours of lecture and 7.5 hours of lab each week for 4 weeks. The lectures and laboratories
will be held on Saturdays and Sundays from 8:30 a.m. to 5:30 p.m. Final exams (lecture courses only) will
take place on Wednesday evening at 6:00 p.m., following the fourth week of courses.
The course requires a significant time commitment from students. This commitment is both in terms of
reading before lectures as well as reviewing the material and doing problems after the lectures. In the
four weeks of classes, we will cover the first eight chapters of the book. Not every topic will be covered
in great depth, but students are expected to study each topic in greater detail through completing the
homework and the labs.
Tests:
There will be 4 non-cumulative tests given during the course of this class. Each test will be administered
at 8:30am on Saturday morning, and will cover any and all material from the previous weekend of class.
The tests will be scantron-based multiple choice tests, so although students will not be required to show
their work, there will be no partial credit for any questions on the tests.
Participation:
Points are received from participation during in-class activities. Attendance is not the same thing as
participation. Students are expected to be involved and engaged in all classroom activities.
Best Practices for studying Organic Chemistry I:
• Read before and read after each class. Skim the chapter before it is covered in lecture in order to
become comfortable with some of the terms associated with each topic. Review each chapter
after it is covered in class to enhance your understanding of what was covered in class.
• Participate during class by taking notes during class and looking over them afterwards. Don't skip
class, arrive late, or leave early. Ask questions for clarification when you don’t understand the
material.
• Stay on top of the homework and assignments. Do the assigned problems as close to the time as
when the topic is covered in the class to increase the depth of your understanding of specific
concepts and to help you learn the material more efficiently and effectively.
• Do not wait until the night before the homework is due to start the assignment. You will get
more out of it if you take the time to really learn the concepts and review the material without
being rushed.
• Find a group of students to study with. Seek out students dedicated to doing well in the course.
This makes studying more fun and also helps you learn the material better by teaching what you
know and learning from your peers what you don’t know. Explaining these concepts to others
will help you learn the material even better.
• Stay focused by finding an environment where you can study with few distractions.
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EVALUATION OF STUDENT LEARNING
Grading procedures: Student assessments may include self-assessments, peer assessments, and
instructor assessments. The format of these assessments may include multiple choice, essay, short
answer, or fill-in examinations; special individual or group projects; or practical examinations, etc.
Assessment
Homework
Participation
Exams
Weight/%/Points
3.70%
3.70%
92.59%
Grading scale:
Letter grades will be assigned only at the end of the block.
A = 90% to 100%
B = 80% - less than 90%
C = 70% - less than 80%
D = 60% - less than 70%
F = less than 60%
I = Incomplete
W = Withdrawal
University Policies
Students are expected to spend at least two hours for each lecture or practicum hour and one hour for
every two laboratory hours of course time per week in activities and assessments outside the classroom.
Examples of activities include, but are not limited to: writing papers; reading articles or text; small group
work; presentations; completing assignments; preparation for assessments; online activities and other
activities that do not include direct instructor interaction and involvement.
All university policies apply to this course and all others. For full policy information please consult the
university SCU Policy Manual. For a quick reference guide to the following policies: make-up
examination, grade posting, results of failing grades, student support information, syllabus amendments,
special needs, student conduct, and attendance, please consult the academic policies document housed
on the Online Student Services [the preceding is a hyperlink].
Student Policy Manual:
The Policy Manual can be easily accessed by:
1. going on to the University Homepage at: http://www.scuhs.edu/
2. Then opening the link for MY SCU
3. Logging on using your university supplied login and password
4. Next, opening the header for “Department”
5. Next opening the header for “Human Resources”
6. Finally, opening the header for the “Policy Manual.”
Withdrawal:
Students can withdraw from any IoS course by submitting a formal withdrawal online. The student
withdrawing from a course must log in to the MySCU portal and click on the "Drop Course" link and
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complete the course drop request. An email confirming the drop request will be sent to the student,
acknowledging the withdrawal.
Disability:
In keeping with the Americans Disabilities Act of 1990, SCU will accommodate a student’s known
physical or mental limitations in order to enable him or her to perform the essential functions of the
curriculum, to the extent the necessary accommodations are reasonable and do not impose undue
hardship to the University. Interested students should request information regarding the services
offered by the University. The Learning Resource Specialists are located in the library and can assist with
the documentation required to access special services due to disabilities.
Academic dishonesty:
Students are expected to adhere to the highest standards of academic honesty. In this class, cheating
will not be tolerated. Plagiarism includes passing someone else’s ideas off as your own without citing
proper credit. Cheating includes looking at another student's test during an exam, allowing other
students to copy your work, use of unauthorized materials during an exam, presenting lab reports that
are not your original work, and recording laboratory data that was not actually observed. These are all
prohibited in this program. Collaboration and discussion are encouraged, but it is important for each
student to individually complete each assignment. Any student who is academically dishonest can
receive a failing grade.
COURSE SCHEDULE
Pre-class assignments:
Any pre-class assignments are to be completed by each student prior to attending class on Saturday.
These assignments must be typed or hand written (must be legible) and physically turned in at the
beginning of class.
Week One: Nomenclature, Conformational Analysis
Details
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•
•
•
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Read Chapters 3.1–3.11, 6.1-6.2, 7.1-7.5, 10.1-10.3C
Lecture Topics
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Participation
Points
Understand line notation.
Become familiar with IUPAC rules.
Name simple organic compounds.
Classify alkanes, alkenes, alkynes, cycloalkanes, haloalkanes, and alcohols.
Distinguish between primary, secondary, tertiary, quaternary centers.
Investigate conformational analysis.
Generate Newman projections.
Quantify stability of conformational isomers.
Textbook
•
Due
Line notation, structural isomers.
IUPAC nomenclature of alkanes, alkenes, alkynes, cycloalkanes, haloalkanes,
alcohols.
Newman projections, staggered vs. eclipsed, anti-conformation, relative stabilities
of different conformations.
Complete the in-class exercises.
Saturday and
Sunday
Sunday
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Homework
The homework assignment is to be submitted online or in-person by the beginning of
lecture on the following Saturday. Refer to the end of the syllabus for homework
assignment.
Test
There is no test the first week of class
The following
Saturday
5
Week Two: Chair Conformations, Chirality
Details
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Read Chapters 3.12-3.15, 5
Lecture Topics
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Points
Analyze cyclohexane chair conformations.
Assess thermodynamic stability of equatorial vs. axial positions.
Define chirality.
Utilize the Cahn-Ingold-Prelog convention.
Define diastereomers, enantiomers, meso compounds.
Determine whether molecules are chiral.
Interpret Fischer projections.
Textbook
•
Due
Cyclohexane chairs, axial vs. equatorial, cis and trans.
Chirality, identifying centers of chirality, symmetry, Cahn-Ingold-Prelog convention,
assigning absolute configuration of stereocenters.
Meso compounds, inversion centers, optical activity, racemic mixtures, chirality in
biological systems.
Diastereomers, enantiomers.
Fischer projections.
Saturday and
Sunday
Participation
Complete the in-class exercises.
Sunday
5
Homework
The homework assignment from the previous week is to be submitted online or inperson at the beginning of lecture on the following Saturday. Refer to the end of the
syllabus for homework assignment.
The following
Saturday
5
An in-class test covering the first week’s material will be administered at 8:30am on the
Saturday of week 2.
Saturday
125
Test
Week Three: Introduction to Mechanisms
Details
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Textbook
Due
Points
Review reaction mechanisms and transition states.
Analyze alkyl halides.
Utilize electron-pushing arrows.
Define nucleophile, electrophile, leaving group, steric hindrance.
Comprehend the details of mechanisms SN1, SN2, E1, E2.
Apply elimination mechanisms to cyclic systems.
Analyze impact of different solvent systems on reaction mechanism.
Predict reaction mechanisms.
Define Zaitsev’s rule.
Read Chapters 4.9-4.10, 4.16A, 6.3-6.21, 7.6-7.9
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Lecture Topics
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Saturday and
Sunday
Energy diagrams, transition states, activation energies.
Nucleophilicity, electrophilicity, leaving groups.
SN1, SN2, E1, E2 reaction mechanisms, electron-pushing arrows. Reactions for linear
vs. cyclic systems, steric hindrance, stereospecificity, solvent systems, Zaitsev’s rule,
degrees of substitution for alkenes.
Predicting reaction mechanisms.
Participation
Complete the in-class exercises.
Sunday
5
Homework
The homework assignment from the previous week is to be submitted online or in-person
by the start of lecture on Saturday. Refer to the end of the syllabus for homework
assignment.
The
followingSatu
rday
5
An in-class test covering all the material from week 2 will be administered at 8:30am on
Saturday of week 3
Saturday
125
Test
Week Four: Addition Reactions
Details
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Points
Understand dehydration mechanisms, carbocation rearrangement.
Characterize addition reactions.
Utilize Markovnikov’s rule.
Define regiospecificity.
Categorize types of catalysis.
Textbook
Read Chapter 7.10-7.11, 8.1-8.14
Lecture Topics
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Due
E1D, E2D, carbocation rearrangement.
Addition reactions: hydrohalogenation, hydrogenation, dihalogenation, hydration,
hydroboration, dihydroxylation.
Markovnikov’s rule, regiospecificity vs. stereospecificity.
Catalysis: heterogeneous vs. homogeneous, syn vs. anti additions.
Saturday and
Sunday
Participation
Complete the in-class exercises.
Sunday
5
Homework
The homework assignment for week 4 is due by the beginning of the final test on the
Wednesday following week 4. Students may hand in the homework at the test, or they
may submit it online. Refer to the end of the syllabus for homework assignment.
The following
Wednesday
20
Test
An in-class test covering all material from Week 3 will be administered at 8:30am on
Saturday of week 4
Saturday
125
Test
An in-class test covering all material from Week 4 will be administered at 6:00 pm on
the Wednesday immediately following week 4. This test will be administered on
campus at SCU.
Wednesday
125
IoS: Organic Chemistry I - LECTURE OCHM311, SP2016
Syllabus prepared by: Mr. Justin Dreyfuss
Revised: 3/2/16
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