• The endocrine system works with the nervous system to allow body parts to communicate with one another and to “adjust constantly to changing incoming signals”, all in an attempt to maintain homeostasis. • Includes cells, tissues and organs (called glands), that secrete hormones into interstitial fluid. • Hormones diffuse from interstitial fluid into the bloodstream. • Hormones are transported by the bloodstream to their target cells. • Exocrine glands secrete substances outside the body. • Ex: sweat glands, oil glands 1) 2) 3) 4) 5) 6) 7) Regulate metabolic processes Control chemical reaction rates Help transport substances across cell membranes Help regulate water and electrolyte balances Plays vital role in reproduction Plays vital role in development Plays vital role in growth • Some hormones are produced in specialized cells of the heart, liver, and gastrointestinal tract. • Most hormones are produced in the pancreas, kidneys, thymus, and pituitary, thyroid, pineal, parathyroid, adrenal, and reproductive glands (ovaries and testes). • Steroid hormones are hormones that are synthesized from cholesterol (lipids). • Ex: estrogen, testosterone, aldosterone, cortisol • Nonsteroid hormones, including amines, peptides, Polypeptides and proteins, and glycoproteins, are hormones that are synthesized from amino acids (monomers of protein). • Ex: norepinephrine, epinephrine, prolactin
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