OBITUARIES For the full versions of articles in this section see bmj.com Wilson Greatbatch Co-inventor of the first practical implanted pacemaker Wilson Greatbatch, born in Buffalo, New York, in 1919, was considered a genius by many. Wilson or Bill, as he was affectionately known, was a creative electrical engineer whose inventions changed medicine forever and have helped save the lives of millions of people around the world. Heart block and bradycardia When Greatbatch died in September, aged 92, his achievements were recognised by media around the world, and he was described as the “father of the implantable pacemaker.” But Greatbatch did not invent the pacemaker. Over the years several people had experimented with electrical stimulation of the heart and the design of artificial pacemakers. By the 1950s, early cardiac pacemakers were in use, but they were large, external to the body, and had to be plugged into an electrical wall socket. A lead was implanted in the patient’s heart. These first pacemakers were used in adults and children for heart block and bradycardia. They helped but caregivers, patients, and their families lived in fear of a power cut. Next came a battery operated handheld pacemaker. Earl Bakken, the US engineer and cofounder of the medical devices maker Medtronic, worked in his Minneapolis garage and developed the first wearable battery powered artificial pacemaker in the late 1950s. This was a huge advance because patients were no longer permanently immobile. The next challenge was to design an implantable pacemaker. In 1958, Rune Elmqvist, an engineer who also had a medical degree, designed an implantable pacemaker when working with the cardiac surgeon Åke Senning in Sweden. Dr Senning implanted the pacemaker in a man with heart block on 8 October 1958, explained Richard Sutton, professor of cardiology at Imperial College, London. The device lasted about six hours but then failed and had to be replaced by a second, which worked for six weeks, and then this was replaced (Tex Heart Inst J 2000;27:234-5). The patient lived another 44 years, dying at the age of 86 (www.nytimes. com/2002/01/18/world/arne-h-w-larsson-86had-first-internal-pacemaker.html). Eduardo Marbán, director of the Cedars-Sinai Heart Institute and a former editor of Circulation Research, said, “Before the implantable pacemaker, patients died routinely from the simplest 906 “Before the implantable pacemaker, patients died routinely from the simplest of causes . . . Everything changed with the implantable electronic pacemaker— often but lamentably taken for granted nowadays of causes: slowing or cessation of the heartbeat. Many of these were babies who had undergone correction of congenital plumbing disorders. The surgery may have been technically impeccable, but they died of cardiac standstill. Everything changed with the implantable electronic pacemaker—a marvel of modern medicine, often but lamentably taken for granted nowadays.” Greatbatch was not actually working on the development of an implantable pacemaker in 1956 when he came up with the idea for his design. Greatbatch left his job as a professor at the University of Buffalo, withdrew $2000 of his savings, and in his barn started to design a prototype. He dedicated two years’ full time work to this goal and created a device only two cubic inches (about 30 cm3) in size. He experimented on restoring heart rhythm in animals, with Drs William Chardack and Andrew Gage. Greatbatch personally made 50 of the first completely implantable pulse generators in the United States, 10 of them for humans. In 1960 he filed for a US patent on the pacemaker, and in 1961 Medtronic purchased the rights to produce and market the “Chardack-Greatbatch implantable pulse generator.” Greatbatch then designed a lithium battery to extend the device’s life because the original lasted only about 18 months. He founded Wilson Greatbatch Ltd in 1970 to manufacture the batteries and other devices. Electrical engineering Greatbatch was awarded a bachelor of electrical engineering degree from Cornell University in 1950. He received a masters degree in electrical engineering from the University of Buffalo in 1957 and held honorary degrees from the State University of New York at Buffalo, Clarkson University, and Roberts Wesleyan College. In 1983 the US National Society of Professional Engineers named the implantable pacemaker one of the 10 greatest engineering contributions to society in the past 50 years. Greatbatch wrote an autobiographical account of his invention, entitled The Making of the Pacemaker: Celebrating a Lifesaving Invention. This “humble tinkerer” never stopped inventing, and when he died he held more than 150 patents. Greatbatch is remembered by his family, friends, and colleagues as kind, wise, humble, deeply religious, and an inspiring teacher and mentor. “He was a wonderful man who really helped his fellow human being,” said Dr Sutton. Greatbatch’s wife, born Eleanor Fay Wright, died in January aged 90; they had been married for 66 years. He leaves a daughter and three sons. His youngest son, Peter, died in 1998. Barbara Kermode-Scott Wilson Greatbatch, electrical engineer (b 1919), died on 27 September 2011 from renal failure. Cite this as: BMJ 2011;343:d6765 BMJ | 29 OCTOBER 2011 | VOLUME 343 OBITUARIES Robert Glen Brackenridge Retired consultant physician, Hexham General Hospital (b 1929; q Edinburgh 1951 ), died on 24 May 2011 from motor neurone disease. Robert Glen Brackenridge (“Robbie”) was born in Cardenden, a Scottish mining village, where his father was the local general practitioner. He won a bursary to the University of Edinburgh to study medicine. After his National Service as a medical officer in the Royal Air Force in Singapore and Kuala Lumpur he trained in medicine in Glasgow, Aberdeen, and Dundee. He was appointed consultant physician at Hexham General Hospital in 1966 and worked there until he retired in 1994. He was involved in setting up the school of nursing and wrote a book, Essential Medicine, which became a standard nursing text. He is survived by his wife, four daughters, and 10 grandchildren. Anna Brackenridge Cite this as: BMJ 2011;343:d6919 Peter Devlin Former consultant obstetrician/ gynaecologist Hereford County Hospital, Hereford (b 1918; q University College Dublin, 1941), d 16 June 2011. After qualifying Peter Devlin (“Pete”) worked for a brief period in general practice and then came to England, where he worked as resident medical officer, specialising in surgery, at what became Hereford County Hospital. In 1945 Pete was appointed deputy medical superintendent at Hereford, and in 1948, with the arrival of the NHS, he was appointed consultant obstetrician-gynaecologist—a post he held until his retirement in 1981. Apart from hospital duties Pete was BMJ | 29 OCTOBER 2011 | VOLUME 343 medical officer for Hereford United Football Club. After retirement he taught children to read at the local primary school. Predeceased by Monica, his wife for over 50 years, he leaves two children and two grandchildren. Ben Moore Cite this as: BMJ 2011;343:d6740 P B S Fowler native India. She was appointed locum consultant at University College Hospital and later became consultant to the SE Canterbury and Thanet health authorities. A clinical all-rounder, she worked as a research fellow in pathology at the Institute of Laryngology and Otology in London. She suffered life long ill health: measles in childhood developed into bronchiectasis in later life. She was a devout Parsi Zoroastrian, first marrying a Hindu from her native city, who died young, and then finding much happiness with her haematologist husband Derek Wells. Rumy Kapadia with the local medical committee. He enjoyed walking, bird watching, running and tennis. On retirement he cycled from Montpellier to Birmingham. He leaves a wife, Dilys; four children; and nine grandchildren. Martin Wilkinson Cite this as: BMJ 2011;343:d6379 James Jack Young Cite this as: BMJ 2011;343:d6747 Former consultant physician Charing Cross Hospital, London (b Shanghai 1921; q St Thomas’ Hospital, London 1944), d 9 August 2011. After qualifying P B S Fowler (Bruce) enlisted in the Army as a captain and was sent to Egypt. He was appointed as an NHS consultant physician at Charing Cross Hospital in 1960. He was also an examiner for conjoint and university finals and the membership of the Royal College of Physicians and the Professional and Linguistic Assessments Board (PLAB). His most important original observation was that premyxoedema (now known as subclinical hypothyroidism) could be responsible for the development of coronary artery disease. He continued in private practice until he was 82. His wife, four children, and 12 grandchildren survive him. Richard Savage Suzanne Savage Cite this as: BMJ 2011;343:d6748 Meher Derek Wells Former consultant otorhinolaryngologist (b 1937; q Osmania Medical College, Hyderabad, India 1960; FCRS), d 24 May 2011. Meher Derek Wells (nee Mehta) was appointed senior house officer in otorhinolaryngology shortly after coming to England from her Brian Richard Wilkinson Former general practitioner Birmingham (b 1927; q Cambridge/ Bart’s London 1949; FRCGP 1986, DObstRCOG), d 25 March 2011. For his National Service, Brian Richard Wilkinson was assigned to Chester Military Hospital. He trained as a general practitioner in Herefordshire and in 1958 moved to Shard End Surgery, Birmingham. He became a hospital practitioner in rheumatology and pioneered inpatient GP beds with the Beauchamp Ward at East Birmingham Hospital. A GP trainer since the mid-1970s he inspected new training practices CORRECTION Barron Bruce MacGillivray Maxwell Caplin Former general practitioner, Paisley (b 1931, q Glasgow 1954), died from jejunal carcinoma on 6 August 2011. James Jack Young (“Jim”) undertook locum posts in general practice before joining the King Street Practice in Paisley. He was pivotal in leading the practice into postgraduate training when this was introduced in 1973. An early exponent of patient centred consultations, he was held in high esteem by both patients and colleagues. After retiring to Oban in 1994, Jim became involved in his church and community. His contributions to Paisley Burns club, Oban Speakers club, and the University of the Third Age were only some of the ways in which he continued to share his knowledge and enthusiasms. He is survived by Sheila, his wife of 15 years; two children; and three grandchildren. Winnie Weir Cite this as: BMJ 2011;343:d6750 Because of a production error, the two photographs accompanying these obituaries were swapped in the print BMJ (issue 22 October 2011, p 847). We apologise to the families of the deceased for the distress this must have caused them. Cite this as: BMJ 2011;343:d6912 907
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