Guide to Esco Products and Services Controlled Environment Laboratory and Cleanroom Equipment Solutions for Life Science, Pharmaceutical, Biomedical and Industrial Research Applications Worldwide Edition, 2010/2011 Guide to Esco Products and Services 1 Table of Contents: Corporate Profile.......................................................................... 2 Biological Safety Cabinets............................................................ 5 Cleanroom Products..................................................................... 6 Compounding Pharmacy Equipment.......................................... 7 Containment / Pharma Products.................................................. 8 CO2 Incubators.............................................................................. 9 Ductless Fume Hoods.................................................................. 10 In Vitro Fertilization Workstations............................................ 11 Lab Animal Research Products................................................... 12 Laboratory Fume Hoods............................................................. 13 Laboratory Ovens and Incubators............................................. 14 Laminar Flow Clean Benches..................................................... 15 PCR Products............................................................................... 16 Ultralow Freezers........................................................................ 17 After Sales Services..................................................................... 18 Esco Product Guide Pictured: Esco Micro Pte. Ltd. is headquartered in Singapore, a modern city state located in Southeast Asia with a population of more than 4 million. From Singapore, Esco manages operations throughout the world. 2 Welcome to Esco Esco’s Vision is to provide enabling technologies for scientific discoveries to make human lives healthier and safer. • A leader in the development of controlled environment, laboratory and cleanroom equipment solutions. • Group total of more than 500 employees. • A world leader in biological safety cabinets. • Products independently tested to international standards. • Headquartered in Singapore. • Large R&D investments, world leading technologies. • North American facilities in Pennsylvania and Ohio Sales, service, logistics for US & Canada. • State-of-the-art production, vertically integrated, 300,000 sq. ft. floor space. • Other Esco locations in Bahrain, China, India, Malaysia, Netherlands, UK. • Worldwide service. • Distributors in more than 100 countries. Pictured: Esco operates 300,000 sq. ft. of state-of-the-art manufacturing space. Products and Application Esco Controlled Environment Equipment Solutions Cleanroom Equipment Pharmaceutical Equipment • Air Showers • Cytotoxic Safety Cabinets • Garment Storage Cabinets • Downflow Booths • Pass Boxes • Pharmacy Isolators • Soft Capsule Cleanrooms • Powder Weighing Balance Enclosures • Straddle Units • Transfer Hatches Laboratory Equipment Biosafety and Laminar Flow Fume Hoods • Class II Type A2 Biological Safety Cabinets • Ductless Fume Hoods • Class II Type B2 Biological Safety Cabinets • Class III Biological Safety Cabinets • Horizontal Laminar Flow Clean Benches • In Vitro Fertilization Workstations 3 • Laboratory Animal Research Workstations Incubators and Ovens Life Science Cold Chain Storage • CO2 Incubators • PCR Thermal Cyclers • Ultra Low Temperature Freezers • Exhaust Blowers • Forced Convection Laboratory Incubators • Fume Hood Airflow Monitors • Forced Convection Laboratory Ovens • Fume Scrubbers • Low Temperature BOD Incubators • Laboratory Fume Hoods • Natural Convection Laboratory Incubators • Remote Monitoring, Data Logging, and Programming Software • PCR Cabinets • Vertical Laminar Flow Clean Benches Global Network Esco Product Guide Not Available in North America Product Development and Innovation Continuous Research and Development An integral part of our business planning effort is based on managing a robust research and development program in Singapore, Shanghai and the USA, balanced against an investment in service support, training and customer education. Compared to industry averages, Esco invests a significant percentage of annual revenues in research and development. As a result of our investment, and with continuous feedback and idea evaluation among our research, global sales, marketing, purchasing and manufacturing teams; Esco products reflect the best contemporary designs in performance, ergonomics and customer satisfaction. • 70 Engineers located in Technology centers in Singapore, China, Indonesia and USA • Growing patent portfolio • Core competencies: - Embedded system, sensor and software development and integration - Containment engineering for biohazards, chemical vapors and hazardous powders - Temperature, humidity, gas and environmental control - Computational fluid dynamics - And many more 4 Manufacturing Quality, Cost, Productivity, Effectiveness, Timeliness Esco's manufacturing advantage stems from our extensive degree of vertical integration, enabled by our world-leading throughput. All processes, with few exceptions, are performed in-house. This allows us to achieve quality and reliability that is truly world-class. Our plant capabilities include: • Incoming materials inspection and warehousing • CNC-controlled sheet metal fabrication and welding • Environmentally-friendly powder coating lines • Electromechanical final product assembly • Electrical / electronics sub-assembly • Multi-step electrical and physical performance testing • Independent quality control at each step in the production cycle • Microbiology, chemistry, containment test labs • Production output of more than 10,000 units per year Esco's focus on quality and timeliness is relentless. Continuous improvement is a mantra. Cross functional teams from Esco Production, R&D, Quality Assurance, Senior Management, are regularly assembled to review and implement areas for improvement. Biological Safety Cabinets 5 The Safety Solution for Life Science Laboratories Esco Biological Safety Cabinets represent more than 20 locally, regionally and internationally-recognized certifications. These accreditations testify to the enhanced performance of Esco products in biological and microbiological applications. Esco is a world leader in biological safety cabinets, offering the industry's widest product range, with thousands of installations in leading laboratories in more than 95 countries around the globe. Esco's biological safety cabinets have earned more independent certifications, in more countries, in more languages, than any other product, demonstrating our commitment to the industry's best safety and quality. Features: • ULPA filters with >99.999% efficiency for particle size between 0.1 to 0.3 microns. • Low noise level. Esco Product Guide • Energy savings. • Ergonomic design. Product lines: • Class II, Type A2 Biological Safety Cabinets. • Class II, Type B2 Biological Safety Cabinets. • Class III Biological Safety Cabinets. • Formalin Vaporizers. • Options and Accessories. Pictured: Esco Biological Safety Cabinets Cleanroom Products Solutions for Cleanroom Applications Since 1978, Esco has been a pioneer in the development of cleanroom technology. Today, Esco operates 300,000 square feet of state-of-the-art cleanroom equipment manufacturing floor space with more than 400 employees. Our vertically integrated capabilities include CNC sheet metal fabrication, stainless steel fabrication, electro-mechanical assembly, and complete performance testing of all products before shipment. Integrated sourcing from the world’s leading component suppliers including Swedish Camfil-Farr® HEPA/ULPA filters, German ebm-papst blowers and fans, enables us to meet your Cleanroom Equipment requirements at a competitive price with rapid delivery. Pictured: Esco Cleanroom Products Esco Cleanroom products include fan filter units, air showers for cleanroom environments, as well as modular clean- rooms designed for small laboratories. Backed by decades of experience, Esco Cleanroom Products offer state-of-theart designs compliant to the latest international standards. Product lines: • Air Showers. • Pass Box and Transfer Hatches. • Soft Wall Cleanrooms. • Laminar Flow Straddle Units, Single and Double. • Garment Storage Cabinets. • Cleanroom Apparel and Clothing. 6 Compounding Pharmacy Equipment 7 The Premium Solution for Sterile Drug Compounding Esco compounding pharmacy equipment includes a complete range of barrier isolators, NSF listed biological safety cabinets and clean benches. Esco Compounding Pharmacy Equipment provides a safe and clean environment for compounding of sterile drug preparations and IV admixtures in compliance with USP 797 criteria. Depending on the nature of compounds being processed, Esco Compounding Pharmacy Equipment can be selected for any of two work zone relative pressure options, all of which feature vertical laminar airflow across the work surface to assure ISO Class 3 level cleanliness within the work area. • ISOCIDE™ antimicrobial coating on all powder coated surfaces eliminates 99.9% of surface bacteria within 24 hours of exposure. Only Esco offers: • Cytotoxic Safety Cabinets. • ULPA filters tested to a typical efficiency of >99.999% for 0.1 to 0.3 micron particles. ULPA filters last as long as conventional HEPA filters and have similar replacement costs. • Compounding Aseptic Isolators. Esco Product Guide • Barrier isolators and biological safety cabinets utilize stainless steel interiors with coved corners. • Barrier isolators feature built-in digital airflow and pressure displays. Product lines: • Compounding Aseptic Containment Isolators (Recirculating). Pictured: Esco Compounding Pharmacy Equipment Containment / Pharma Products Esco Solution for Containment / Pharma Applications Esco offers a complete range of solutions designed for pharmaceutical processing in both the containment and aseptic processing fields. The increasing potency of today's pharmaceutical compounds, as well as demanding health and safety requirements, have led to a greater need for containment equipment in the manufacture of pharmaceuticals. Rapid regulatory developments have also occured in the aseptic processing field, pushing manufacturers of parenterals and aseptic products to meet ever-increasing quality criteria. Pictured: Esco Containment / Pharma Products Pharmaceutical dispensing, sampling and charging operations are now safer and more efficient with the Esco range of Pharmacon™ Downflow Booths. Harnessing Esco's experience of close to 30 years in clean air and containment equipment design for the pharmaceutical industry, these booths offer dependable performance in compliance with the latest environmental and operator safety standards. Laboratory operations involving weighing, mixing and dispensing hazardous or nuisance powders can now be performed safely and economically with the Esco Powdermax 1 Powder Weighing Balance Enclosure. Product lines: • Downflow Booths. • Powder Weighing Balance Enclosures. • Aseptic and Containment Isolators. 8 CO2 Incubators 9 Cradle for Beautiful Cells Sleek, reliable and intuitive, Esco CelCulture CO2 incubators provide comprehensive sample protection that brings your scientific dreams one step closer to reality. cultures. Typical fields of application include tissue engineering, in vitro fertilization, neuroscience, cancer research and other mammalian cell research. Features: • Stable, uniform distribution. • ULPA filters. Introducing Esco CelCulture® - world class CO2 incubators from Esco with the technologies and compliance to prove it. Precise parameter control, robust contamination control with ULPA filtration system and 90°C moist heat decon. CO2 incubators are widely used in scientific research to grow and maintain cell Esco Product Guide • Full stainless steel interior, ISOCIDE antimicrobial coating on exterior surface. • Intelligent data & event Logger. • Alarm system. • 90˚C moist heat overnight decontamination cycle. Pictured: Esco CelCulture® CO2 Incubators Ductless Fume Hoods The Safe, Energy Efficient Solution for Modern Chemistry Esco Ascent Ductless Fume Hoods provide protection to both laboratory personnel and the environment from toxic fumes. Esco Ascent Ductless Fume Hoods are quickly becoming a viable alternative to conventional fume hoods. Unlike conventional fume hoods, these hoods filter out chemical fumes and recycle air directly back to the laboratory, providing energy savings, personnel and environmental protection, convenience as you do not have to deal with complicated ducting systems, and mobility, since ductless hoods are independent systems which do not require connection to extraction systems. Pictured: Esco Ductless Fume Hoods Esco ductless fume hoods are independently tested by INVENT-UK for the ability to filter contaminated air with efficiency and retention capacity as required by the British Standard BS 7989 and French Standard AFNOR NF X 15-211. Fume containment and airflow uniformity meet the requirements of ASHRAE 110-1995, BS 7258, EN 14175-3 and AFNOR NF X 15-203. The Esco combination of high performance and carbon filtration opens new, cost effective applications for fume hood technology in schools, classrooms and laboratories. Associated products include Esco chemical storage cabinets. 10 In Vitro Fertilization Workstations 11 Esco In Vitro Fertilization Workstations Esco IVF workstations are specially designed for use in fertility laboratories in the fields of human and animal reproduction. A controlled work environment is of high priority due to the complexity of the process. This includes hygienic conditions to minimize microbial contamination, a warmed work surface for the sustenance of biological matter and provisions for the use of microscopes. The Labculture IVF workstation incorporates a number of features to ensure operator comfort and enhanced productivity: is designed for maximum operator comfort. • Built-in warm white, electronically ballasted, 5000k lighting provides excellent illumination of the work zone and reduces operator fatigue. The reliable lighting system is zero-flicker and instant start. • The removable perforated filter diffuser provides protection to the filter and improves airflow uniformity. • The workstation interior is constructed of stainless steel, making the work zone easy to clean. The interior surface will not chip, rust or generate particles. • The ergonomically designed work surface with a curved front edge Esco Product Guide Pictured: Esco IVF Workstations Lab Animal Research Products Esco Solution for Animal Research Laboratories Animal research, cage changing and bedding disposal procedures are now simpler, safer and more productive with the Esco range of VIVA® Lab Animal Research Products. Pictured: Esco Lab Animal Research Products Esco experience in clean air and containment technologies extends to lab animal research products to help protect the investigator, animal technicians, animals and the environment during research, cage changing and bedding disposal procedures. Esco lab animal research products help laboratories comply with NIOSH recommendations to create a safer, more productive and healthier work environment. tact; hazards related to the technique or materials or biohazardous substances that may be used during the course of animal research. Esco applies decades of experience in clean air technologies to the animal research laboratory, protecting personnel and the laboratory environment from hazards related to the equipment, materials and practices used in performing routine animal husbandry; hazards relating directly or indirectly to animal con- • B e d d i n g D i s p o s a l A n i m a l Containment Workstations. Product lines: • Universal Access Animal Containment Workstations. • Dual Access Animal Containment Workstations. • Air Showers. 12 Laboratory Fume Hoods 13 Laminar Topography and Perfect Protection Perimeter Laboratory fume hoods serve to control exposure to toxic, offensive or flammable vapors, gases and aerosols. The laboratory fume hood is a type of local exhaust ventilation system (engineering control). A typical fume hood is a cabinet with a moveable front sash (window) made out of safety glass. A properly used and functioning fume hood exhausts hazardous gases, dusts, mists, and vapors from a confined location and helps protect workers from inhalation exposure. Product lines: • General Purpose Benchtop Hoods. • Acid Digestion Hoods. • Perchloric Acid Hoods. • Radioisotope Hoods. • Floor Mounted Hoods. Esco fume hoods have been independently tested by INVENT-UK to pass the American standard ASHRAE 110-1995 and British Standard BS 7258 (determining fume containment capability). They have also been successfully tested for fume containment specified in the European Standard EN 14175-3. • High Performance, Low Flow Hoods. • Educational Hoods. • Polypropylene Hoods. • Chemical Fume Scrubbers. • Exhaust Blowers. Pictured: Esco Laboratory Fume Hoods Esco Product Guide Laboratory Ovens and Incubators Reliable Performance For Universal Applications Introducing Esco Isotherm® - world class laboratory ovens and incubators from Esco with the technologies and compliance to prove it. Esco Isotherm® - world class laboratory ovens and incubators encompass ergonomics, intuitive interfaces, microprocessor PID controls with programming options, a 4-zone heated air jacket and a precisely tuned and tested ventilation and insulation package, all supported by Esco’s solutions - based sales and service representatives worldwide. Product lines: • F o rc e d C o n v e c t i o n L a b o r a t o r y Ovens. • F o rc e d C o n v e c t i o n L a b o r a t o r y Incubators. Pictured: Esco Laboratory Ovens and Incubators • Natural Convection Laboratory Incubators. • Low Temperature BOD Incubators. • Vo y a g e r R e m o t e M o n i t o r i n g , Datalogging, Programming Software. 14 Laminar Flow Clean Benches 15 The Leading Solution for Research Laboratories Esco is the world leader in premium laminar flow cabinets for the global life sciences market. Esco is an industry leader in the development of professional quality laminar flow clean bench cabinets. With tens of thousands sold throughout the life sciences market worldwide, Esco has reinforced its reputation for dependability by providing reliable protection for samples and work processes in a multitude of applications. for the discerning researcher and offering a combination of value, high quality construction, low operating noise levels, and a wide product range to suit all budgets. Our selection of Vertical, Horizontal and Specialty clean bench cabinets offers a variety of choices for installations where high quality construction is essential. Our clean bench cabinets are aerodynamically engineered and use only premium quality ULPA filters with integrated motor/blower assemblies for quiet operation and long service life. Since 1978, Esco has emerged as the industry leader producing laminar flow cabinets that are the premium selection Esco Product Guide Pictured: Esco Laminar Flow Clean Benches PCR Products Esco Reliable Solution for PCR Process Esco PCR products are used in genomics, proteomics, molecular biology and forensic sciences where DNA amplification is required. Polymerase Chain Reaction (PCR) is an in vitro method of nucleic acid synthesis useful in the detection and analysis of DNA and RNA in cell and molecular biology investigations. Through PCR, a small, unique segment of DNA can be specifically replicated, exponentially amplified and easily analyzed. Because PCR depends on repeated cycles of heating and cooling within a sample block, rapid temperature ramping, precise temperature control, block uniformity and flexible segment programming are essential performance attributes of a Thermal Cycler. Pictured: Esco PCR Products Esco offers a choice of Conventional Thermal Cycler and Real Time Thermal Cycler models designed to meet critical requirements for all kinds of PCR pro- cesses, such as, Gradient PCR, Touch down PCR, High throughput PCR, in situ PCR and so on, using a variety of PCR tubes, strips, plates and slides. The Swift thermal cyclers use state of the art Peltier temperature control technology to achieve and maintain precise control and fast ramp rates with minimal over or under-shoot for process speed and accuracy. Esco real-time and programmable thermal cyclers, shaking micro incubators and accessories fulfill an emerging demand for complementary products found in the same laboratory environments as the company’s clean air and laminar flow line. Not available in North America 16 Ultralow Temperature Freezers 17 Esco Ultralow Temperature Freezers The Perfect Storage Environment for Beautiful Cells. • Energy Efficient - 130mm (5") foamed polyurethane insulation, triple gasket seal, full wrap copper evaporator, balanced system design. • Quiet - extremely low operating noise levels ensure a perfect working environment. • Reliable - proven components, dual condenser fans; clean, dry and leakfree refrigeration systems. • Balanced Design - thermodynami cally engineered for precise balance between high and low stages, improves operating efficiency and reliability. • Warranty - 5 years on compressors, 2 years on complete system. • Capacity - larger volumes than the competition in the same class. Esco Product Guide Pictured: Esco Lexicon® Ultralow Temperature Freezers After Sales Services Esco After Sales Services Parts Availability Whenever service is needed and parts are required, minimizing downtime is a critical objective. Statistical usage analysis helps Esco predict parts life, permitting Esco to manage logistics and stage proper inventories around the world. The combination of predictive maintenance, historical data and geospecific proximity assures our customers that parts and labor are available whenever service is scheduled through the local sales organization. Registration, Documentation and Instruction Quality control at Esco extends from research and development through engineering, manufacturing, shipment, delivery and customer feedback. Esco maintains an aggressive program to encourage warranty card registration by mail, email or online submittal so that we know where Esco products are located and how they are being used. Data from our warranty registration program is confidential and provides us with valuable contact information should we ever need to notify you about your Esco product. All Esco products include unique serial numbers for identification. Documentation for all performance tests is archived and maintained for customer reference. Online Technical Information . escoglobal com LIVE SUPPORT . escoglobal com LIVE SUPPORT Site preparation instructions are useful before product arrival and installation. Installation and start-up manuals, operations manuals and quick reference guides are available anytime from the Esco Library online. An interactive online LiveSupport™ concierge center accessible through the Esco Web site offers extended hours of operation. LiveSupport permits users to dialogue directly with Esco personnel. References and Links For more about Esco products, markets, employment opportunities, history, education, information resources, and Singapore, visit our information portal at www.escoglobal.com. 18 Esco Micro Pte. Ltd. • 21 Changi South Street 1 • Singapore 486 777 Tel +65 6542 0833 • Fax +65 6542 6920 • [email protected] www.escoglobal.com Esco Global Offices | Breukelen, The Netherlands | Kuala Lumpur, Malaysia | Manama, Bahrain | Mumbai, India | Philadelphia, USA | Salisbury, UK | Shanghai, China | Singapore ©2010 Esco Micro Pte. Ltd. Specifications Subject to Change. ES1553_V1_5K_08/10 Esco Technologies, Inc. • 2940 Turnpike Drive, Units 15-16 • Hatboro, PA 19040, USA Toll-Free USA and Canada 877-479-3726 • Tel 215-441-9661 • Fax 215-441-9660 us.escoglobal.com • [email protected]
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