ENABLING THE BIO-ECONOMY
APPLICATIONS CENTER
PROCESS OPERATIONS CENTER
BIOTECHNOLOGY CENTER
15 T W Alexander Drive
Durham, NC 27703, USA
5516 Industrial Park Road
Norton, VA 24273, USA
Génavenir 1, 1 rue Pierre Fontaine
91000 Evry, France
The Current Bio-Economy Disconnect
Non-food biomass
High sustainability
High availability
Low revenues
Biobased applications
Limited sustainability and
high price volatility of
source material
High value
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Enabling a sustainable bio-economy
Bio-based
C5; C6 sugars
& lignin
Non-food biomass
chemicals
materials
animal feed…
Benefits
o
o
o
o
o
Significantly improve the economics of lignocellulosic chemicals production,
Significantly reduce the loading and the cost of enzymes
Improve sugar and co products yields
Avoid production inhibitors
Improve overall process economics
Arbiom’s Value Proposition
Current applications
Ligno
cellulose
Glucose
430kg
Pentose
Bio-ethanol
Lactic acid
Citric acid
$127bn in 20131
Xylitol
$670m in 20132
195kg
Lignin
250kg
Energy
Phenolic resins
Road binders
$300m market4
Others
1000kg
125kg
Emerging
applications
Advanced fermentation
applications
• Butanol
• Succinic acid
• Butanediene
• …
$1,4tn bio-economy market3
BTX
Carbon fibers
Activated carbon
…
$130bn addressable market5
Bio-fertilizer
$595+
$0-$100
Opportunities for the fermentation-based chemical industry – Deloitte 2012
Xylitol – A Global Market Overview - Report buyer 2013
The Advanced Biofuels and Biochemicals Overview - Silicon Valley Bank 2012
4 Transparency Market Research
5 High value opportunities for lignin – Frost and Sullivan 2012
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Arbiom’s Protein Production
Ligno
cellulose
Fractionation
+ Hydrolysis
Lignin burned for energy
1000kg
Cell
growth
Media
C5, C6,
phosphates
Protein
rich
(60%)
Animal
Feed
Yeast growth
+ separation/drying
335kg
650kg
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Patented bio-compatible technology
Biorefining technology developed by a biotech company
Respect of the value of living material: low temperature, phosphoric acid
• Low temperature preserves all components of the biomass
• Phosphoric acid lowers enzyme cost and maximize compatibility
• Compatible with wide array of lignocellulosic materials
Pretreatment
C6 sugars
C5 sugars
Lignin
Enzymes
Lignocellulose
Bio-fertilizer
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Technological advantages
Classic 2nd Gen
Severity
Lignin output
Cellulose output
fermentability
Residue
Corrosion
Feedstock
Plant size
Hydrolysis time
Enzymes requirements
ARBIOM
High severity
Low severity
>150°C, entails chemical degradation
<70°C, preserves chemical structures
Burned
Valorized as chemical
Degraded lignin burned for energy
High value chemical
Crystalline
Amorphous
Low reactivity, contaminated with inhibitors
High reactivity, no inhibitors
Low , with inhibitors
High – no inhibitors
Contaminated with inhibitors
High reactivity, no inhibitors, laced with phosphates
Requires need detoxification
Fertilizer
due to products/biomass degradation
Minerals with traces of phosphates
High
Low/none
High temperature and/or strong acid
Low temperature, weak acid
Specific
Agnostic
Successfully tested on most LC biomass
Large
Small to large
Requires concentrated production of vast amounts of
biomass
Can accommodate distributed biomass production
through smaller units
72h
24h
High
Very low
High enzyme OPEX costs
Complex cocktail
Low enzyme OPEX costs
Easier enzyme cocktail optimization
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De-risk Development
Arbiom plateform can be used in various process steps for optimal results in
conversion of lignocellulosic material to value-added chemicals.
It is the first taillored solution designed to improve the performance of strains
and to optimize the overall economics of bioprocesses
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Locations
USA Applications Center
Durham, NC
USA Process Operations Center
Norton, VA
France Bio-Technology Center
Evry, France
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Technology Projections, new value
creation
 Feed applications from non-food biomass
o Inhibitor less cellulosic sugars with traces of phosphate are a
perfect substrate to optimize the growth of non GMO single cell
proteins.
o High yield, low footprint proteins for animal feed
o Perspective for L Lysine and Methionine optimized proteins
 Consolidated bio-process
o Amorphous cellulose is “easy” to hydrolyze: single organism can
combine both hydrolysis and conversion operations
o Demonstrated in lab on lactic and succinic acid
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Business Model 1/2
Licensing of technology
Bio-refineries (co)-operation
Revenue Model
Sale of licenses
Sale of consumables (enzymes)
Deployment services
Sell of bio-based intermediates
produced by biorefineries (co)
developed and owned by Arbiom
Biobased chemicals, fuels and
materials applications operators
Clients
Biomass producers (agriculture and
forestry)
Biomass stakeholders (pulp an
paper, energy)
Fuels and chemical industry
players intending to secure
biobased sourcing
Capital
requirements
(supported by third party)
++
(financing of industrial units)
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Business Model 2/2
250kt Bio-refinery
CAPEX
$174M
OPEX
$71M/year
Revenues
$149M/year
Technology licensing
Operations
License
$11.2M
Invested capital
$70M
Rev engineering
$3.5M
Debt
$104M
Rev enzymes
$8M/year
EBITDA
$78M/year
NPV
$531M
IRR
36,4%
Arbiom will also engage in structuring
projects for 3rd parties (securing of sites,
permitting, applications) that will increase
the value of the license
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2015-2016 Operations Plan
 Set up strategic partnerships with
“suffering” biomass stakeholder
 Construction of 5kt/year integrated plant
(showcase, revenue generation and
application scale up support)
 Structure application platform to secure
downstream application
 Design of 40kt/year plant
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2017 Operations Plan
 Continued operation of 5kt plant for:
- commercial demonstration for bio
chemical industry
 - production of high value feed product
 Design of 40kt plant for production C5
Lignin and high value feed product.
 First license sale to strategic partner
 Secure new customers.
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Key element of Arbiom business
plan.
Arbiom is currently raising funds for expanding Arbiom
novel biorefinary proposition and expand globally both its
technology and the sales of high value biobased product.
 Arbiom plans to build the first production plant for the
processing of woody biomass and the production of a
proprietary stream of highly fermentable
carbohydrates’ and high quality lignin.
 The carbohydrates of the plant will be transformed into
high value feed products for the essential nutrition
need of the world.
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