9/13/2016 Bio100 (Dr Paddack) Lecture 6 (9/12/16) I. Building blocks of life (Ch 3) A. Water – why is it important to life B. Carbon – why is it the basis of life? C. Organic Compounds 1. Sugars/Carbohydrates 2. Lipids a. Fats b. Phospholipids c. Steroids 3. Proteins 4. Nucleic Acids a. DNA b. RNA c. ATP II. Membrane structure & function (Ch 5) A. Membrane structure B. Getting stuff in/out of cells 1. Passive transport a. Diffusion b. Osmosis c. Facilitated diffusion 2. Active transport 3. Exocytosis 4. Endocytosis Why is life carbon-based? 1 9/13/2016 Carbohydrates: carbon, oxygen, hydrogen Biomolecules Molecules that are essential to cell structure and function, and that are constructed by living organisms Four types of large biomolecules sugars lipids proteins nucleic acids Functions: 1) Glucose storages for later use as fuel (polysaccharides, eg starch) 2) Physical structure (eg, cell walls; chitin) Figure 3.7 Lipids carbon, oxygen, hydrogen, & sometimes others (phosphorus, sulfur, etc) Fats Glycerol Three types of lipids: 1) Fats 2) Phospholipids 3) Steroids ‘Role’ of fats - Long term energy storage Fatty acids 2x as much energy as sugar (per unit weight)!! Functions of Fats protection waterproofing buoyancy insulation 2 9/13/2016 Fat Vs. (triglyceride) Phospholipids Phosphate group Glycerol Phosphate group Glycerol lipid bilayer – cell membranes Hydrophilic heads Hydrophilic head Water Hydrophobic tails Symbol for phospholipid Hydrophobic tail Lipids Water Proteins carbon, oxygen, hydrogen, nitrogen Three types of lipids: 1)Fats 2)Phospholipids 3)Steroids Steroids: lipids that act as signaling molecules inside and among cells. Their presence initiates expression of certain genes (DNA segments). enzymes Protein Functions hemoglobin Poisons, etc hormones structure 3 9/13/2016 Nucleic Acids: carbon, oxygen, hydrogen, phosphorus, nitrogen a nucleic acid – energy currency of organisms DNA ATP – cell ‘currency’ 4 9/13/2016 Lecture 6 (9/12/16): Study Questions 1. Why is water so important for life? 2. Describe why carbon is capable of bonding with other molecules (thus creating an excellent ‘skeleton’ for biomolecules). 3. Define isomer. 4. Define organic compound –list the 2 elements in all organic compounds and the 3rd element in most organic compounds. 5. List the elements in each of these types of organic compounds: carbohydrates, lipids, proteins, nucleic acids. 6. List 4 functions of fats 7. How do fats differ from phospholipids? 8. Understand how the lipid bilayer forms. 9. Define steroid – what type of compound is it? Provide 1 example. 10. List 5 different functions of proteins. 11. Define enzyme – why are they important? 12. Why do proteins need a specific range of temperature & pH to function? (think of your lab from this week) 13. Define: DNA, gene, RNA, ATP 14. Define: diffusion, osmosis (last week’s lab). 15. Be able to determine which direction osmosis will occur when a cell is in water that is saltier and when in water less salty than it (from last week’s lab) – remember, salt follows water. 16. Most molecules are too large (and too charged) to pass thru the lipid bilayer. List 2 different ways that molecules can be brought into or out of a cell. 5
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