T H E USE OF HYPNOSIS IN T H E CARE OF THE CANCER PATIENT BYRONBUTLER,M.D., I that is important in cancer, for it alone carries the burden of the disease.37 Hans Zinsser expressed this thought when he said: “As it is, my mind and my spirit, my thoughts and my love, all that I really am, is inseparably tied up with the failing capacities of these outworn organs.” Philosophically, only mind is important. We need not stress the treatment of cancer, for that is the main intent today. T h e attack on cancer has been so consistently emphasized that the emotional aspect of this disease is entirely in the background. At this time when radical surgery, high-voltage radiotherapy, glandular extirpation, hormone administration, and radioactive drugs are used freely, it may be timely to appraise that cancer patient who is an individual with a death sentence. Most of us with our occidental philosopsy of life, believe that death is the end of consciousness, and few approach it without the feeling of Hamleto? when he said that death is a land Erom which no traveler returns. Certainly, this threat of extinction is the most difficult problem the conscious mind has to reconcile. This psychological approach may be traced to Freud’s4 revolt against the cellular philosophy of Virchow, and, as a result, our knowledge of functional disease has been greatly enriched.3. % 16, 22* Mental factors in what were previously considered to be purely organic disease, such as hypertension,2, 48 diabetes29 tuberculosis,6 ulcerative colitis,17 and peptic ulcer, Cave been demonstrated. Finally Virchow’s own citadel has been invaded, and the cancer patient has been found to exhibit defenses identical with those observed in psychoneurotics.e* As the microscope, Virchow, and Pathology led to the great advances in exact laboratory investigation and physical medicine, so did mesmerism, Freud, and Psychiatry lead to an T IS ONLY THE MIND MED.SC.D. understanding of the mind. Since i t has been clearly indicated that there are important emotional disturbances in patients with cancer,68it is to be expected that these reactions will vary from patient to patient. If the emotional tension present in these patients can be channeled away from a neurotic exaggeration of fear and !self-pity to a more constructive and realistic point of view, then this energy could be available to support the patient during therapy and, when that is finished, to give him a more serene and confident attitude until the end. With such an approach there will be less pain, less disturbance in bodily function, and a reduction in the degree of dread that surrounds the subject of cancer. Hypnosis has many attributes that lend themselves to this problem. Indeed, it can be used to suppress symptoms or through application of analytical principles to express emotionally charged ideas. It allows, at least in some patients, a control over the subconscious mind in spite of resistance by and without the knowledge of the conscious mind. Thus, the mind can be maneuvered to aid the cancer patient in his struggle for survival. The therapist is like the master of a marionette, who can manipulate his charge as required by the occasion. T h e act can run smoothly if the master is capable of his task, but it may be disastrous if he does not know each phase of the plot. I HISTORY Arnold J. Toynbee has made history a useful study, for from it one learns not only what has happened in the past, but also what may occur at the present, and what is likely to develop in the future. It is in this vein that a brief sketch of the history of hypnosis is presented. Hypnosis is older than medicine. It was used by the adepts before the medicine men had From the Department of Obstetrics and Gynecology, separated from the priests. More than 3000 College of Physicians and Surgeons, Columbia Univer- years ago it was used in India2’ and in the sity, Sloan Hospital for Women [Columbia-Presbyterian Medical Center] and the Francis Delafield Hospital, British Museum there is a bas-relief taken from New York, New York. a tomb in Thebes that shows an Egyptian hypPartially supported by a grant from the American notist and his ~atient.~T Aesculapiusl5. 72 was Cancer Society, Lnc. able to relieve pain by stroking with his hands Received for publication. April 24. 1953. 1 2 CANCER January 1954 to induce long a n d refreshing sleep in his patients, while, according to Tacitus,lb Hippocrates spoke of impressing health on the ill by “passes.” T h e pertinent history of hypnosis can be divided into four periods. Each period has been characterized by a crescendo, a fortissimo, and finally a pianissimo. I. Period of Magnetism (1587-1789). T h e first period began with Cardan’s Works on Precious Stones, 1584,s in which he reported an experiment whereby anesthesia was produced by a magnet. P a r a c e l ~ u sbelieved ~~ that the human body exhibited magnetic properties, and in forbidden writings Maxwel1,s van Helmont,72 and others propounded the theory that in the magnet one could find the universal principle that could explain all natural phenomena. Influenced by these writings and his own doctorate thesis, De Planetorunz Influxir, 1766,53 Franz Anton Mesmer formulated his brilliant theory on animal magnetism, which he published in Paris i n 1779.30 This theory was summarized in twenty-seven propositions or axioms, which postulate that there is a “magnetic fluid” that permeates the whole universe. It is because of this that “impressions” from one part may be transmitted to and may influence another; for to this incomparably rarified substance there is no vacuum. This material may be communicated, propagated, and concentrated by sound, mirrors, and light. H e believed that his “fluid” was important in medicine and that, when the physician understood it, he could diagnose, cure, and prevent disease. This theory is today still thought-provoking, for fundamentally the first part differs little from a theory of the universe presented recently by Herbert L. Samuel. Mesmer became fascinated with the “crises” he produced and thought the proof of his theory required curing of illness by this means. T h e Commission appointed b y Louis XVI denied him this evidence, and from their experimental studies they concluded that these “crises” were due to the imagination of the patient. T h e investigators coidd neither feel, hear, nor see “animal magnetism,” therefore how could it exist? Also they showed great concern about the possible moral abuses of it,a*52 for was not the subject the pawn of the magnetizer’s will? With this crushing defeat Mesmer left Paris, but before this great first chapter closed Count Maxime de Puys6gur,lg a pupil of Mesmer, demonstrated the phenomenon of “somnambulism” and described how, on awakening, the subject had complete amne- VOl. 7 sia for the trance period. H e also called attention to the ability of the somnambulist to feel and describe accurately conditions in other bodies and to prescribe cures for them. Edgar Cayce’s work utilizing this phenomenon ten to fifteen years ago has been reported in Theye Is a River.71 PuysCgur’s work, however, could not reverse the charges already made, and animal magnetism slipped from prominence with the upheaval of the French Revolution in 1789. II. Mesmerism (1823-1860). When the French Academy appointed a second Commission of nine men to restudy magnetism in 1823, a revival of interest occurred. After a five and a half year period this Commission reversed the opinion of the first. They concluded that “research on magnetism should be encouraged as constituting a most curious branch of psychology.”B T h e Commission undoubtedly realized that there was something to mesmerism when they observed the following case, which was referred to by Pyne, Elliotson, Hollander, and Didier. Briefly, M. le Docteur Chapelain had used mesmerism over a period of several months to relieve the suffering of Madame Plantin, who had a n ulcerated cancer of the right breast with massive enlargement of the right axillary lymph nodes. He was able to induce “a profound sleep in which sensation appeared suspended, but intellect remained perfect.” On April 1, 1829, in Paris, Chapelain “threw her into a mesmeric sleep” and Jules Cloquet removed the breast and dissected out the axillary nodes. T h e operation lasted ten to twelve minutes and during this time the patient conversed calmly with the operator and gave not the slightest indication of pain. T h e wound was closed with sticking plaster. T h e patient was pvt to bed and left in a mesmeric state for ten hours. An important figure at this time was John ElliotsonzE of London, who introduced Laennec’s stethoscope into England. He was also the first Professor of the Practice of Medicine at the University Hospital, 1831. Elliotson believed in Mesmer’s theory and staked his reputation upon the belief that a coin of nickel would mesmerize, while a coin of lead would not. When, in a crucial experiment, Thomas Wakely, the editor of the powerful Lancet, switched the coins by subterfuge, of course, Elliotson was defeated. H e was forced to give u p his academic position but continued to have a large practice, published a new journal, T h e Zoist, and had such eminent admirers as No. 1 - USEOF HYPNOSIS IN CARE OF CANCER PATIENT Butler 3 With the discovery of chloroform62 and ether13 this period of attempted useful application of mesmerism came to an end. T h e case of a man whose right knee was like “a ZZZ. Braidism-Hypnotism (18434900). bag of bones.” T h e patient was in such agony With James Braid, a Manchester surgeon and that he had not slept for three weeks, could not eat, and had excruciating pain if anyone oculist, we enter the scientific phase of hypwalked heavily across the room. He was mes- nosis.9 Braid recognized that with the inducmerized on three successive days. His pain tion of the mesmeric state, the eyes exhibited was relieved and he ate and slept. On the third a peculiar type of movement that he thought day his leg was amputated above the knee was of a reflex n a t ~ r e . 7He ~ broke away from without evidence of pain. When he was awak- Mesmer’s theory and believed that the “state” ened, he did not know the operation had resulted from some physiological change in the occurred. individual induced by tiring the eyes, and this James Esdaile, inspired by Elliotson, used resulted in a peculiar physiological condition mesmerism to perform painless operations up- of the brain and the spinal cord. It was Braid on the natives of Bengal. In 1846, he per- who recognized the importance of suggestion formed seventy-three major operations and re- and devised the name “hypnosis.” Volgyesi lieved pain in eighteen medical conditions. He considers that he was not only the founder of used trained natives to perform the mesmeriza- scientific hypnotism but also the father of tion, while he performed the operations. Most psychosomatic medicine. T h e Nancy School, largely represented by of his cases were witnessed by reliable observers, who traveled great distances to his little coun- LiCbeault56 and Bernheim, believed that hyptry hospital in Hooghly, India. He was later notism was closely allied to natural sleep and to learn upon his return to England that the was largely a product of suggestion, while the philosophical, oriental mind of the Bengalese Paris School, headed by the noted neurologist, lends itself to a greater depth and a greater Charcot, thought that it was a pathological ease of induction than the mind of the average state, a neurosis, and that it was due to a Englishman. The native magnetizers used somatic change. There was great rivalry bepasses mainly, and certainly, in this accurate tween these two groups, but the Nancy School record of profound mesmerism, there was little won out and received official recognition from use made of suggestion, which is thought to be the Academy of Medicine in Paris.7. 86 T h e use all-important today. In every case reported by of hypnotic and suggestive therapy became Esdaile there was irrefutable evidence of con- comonplace throughout the world, but there trol of pain, and at least twelve of his cases was little attempt to select suitable cases, nor could have been cancerous tumors. Typical of could it live u p to the exaggerated claims made by its proponents. By 1900, it fell into disuse his cases is the following report: again. “Oct. 25, 1845. G . S., a shop-keeper, aged 40. During this period, however, it was directly He has a ‘monster tumour,’ which prevents him applied to the control of pain in a few cancer from moving because of its great weight. He patients. Tuckey referred to reports by Arthur has used it for a writing desk for years. He became insensible on the fourth day of mesmer- of the East-End Wesleyan Hospital: ism, and I removed it with a circular incision. Arthur used hypnotism to relieve pain in cases T h e rush of blood was great, but was soon of cancer of the uterus and breast and, by this arrested. The tumour weighed eighty pounds. means, he achieved excellent palliative results. On recovery, he said that nothing had dis- The pains, however, returned from time to turbed him.” time, and it was impossible for the patients always to go to him for relief. He, therefore, Didier reports in detail: hypnotized them and told them that, whenever A case of cancer of the breast which was re- their symptoms recurred, they had only to take moved by Mr. Tubbs in 1854. The patient was a dose of the medicine he would give them, and mesmerized, the breast and axillary nodes re- they would experience immediate relief. This moved, and the wound edges sutured. T h e pa- procedure was successful and he termed this tient was awakened and stated without res- method “treatment by indirect suggestion.” ervation that she felt no pain during or after I V . Hypnology, Narcoanalysis, Hypnoanalythe procedure. Doctor Elliotson, Col. Baynold, Dr. Symes, Mr. Goff, and Mr. Amon were sis (2900-1953). During the past fifty years through the application of laboratory experiwitnesses. Charles Dickens and William Thackeray. Elliotson described: 4 CANCERJanuay 1954 mental techniques, hypnotism has become established as a science.36 “hypnology.”12. 75 Those who use this science constructively may be called “hypnologists.” This science has a secure basis with its tenets anchored on experimental measurements. Thus, muscular strength,57. 8 1 cerebral function,28*46* 69 gastric secretion,45 and respirat0ry3~and cardiovascular actions39.449 76 have been studied as they are influenced by the hypnotic state. Also pertinent to this report are experimental investigations of hypnotic anesthesiaz3-59v upon which is based the rationality for the use of hypnosis to relieve pain in cancer. Its effect upon recall of past memories,38 the duration of posthypnotic amnesia,TO and even its possible antisocial useslo. 259 64, 77, 79, 80 have been scrutinized. Because of this, there has gradually been a diminution in both professional and popular resistance to hypnosis. Another impetus to social acceptance was the development of narcohypnosis and narcoanalys i ~ 34. ~ T h~e ~use of drugs made these procedures more acceptable. It has been said that if psychotherapy is ever to reach the masses, it will be through a method more rapid than psychoanalysis, such as hypnosis. This challenge has been acted upon by Brenman and Gill11 and Wolberg, who have combined hypnosis and psychoanalytical principles into an integrated form of mental therapy, “hypnoanalysis.” During this fourth period there were also a few isolated reports on the use of hypnotism to relieve the pain of cancer. Miller refers to a case treated by Betts Taplin: His patient was a 66-year-old man who had a carcinoma of the cardiac end of the stomach diagnosed by a laparotomy. Taplin describes his results in the relief of suffering in this patient who was getting morphine frequently and was losing ground rapidly one month postoperatively. “I resolved to try what hypnotic suggestion would do toward smoothing the way to the inevitable end. The result exceeded my expectations. After the first sitting he was much easier, and slept fairly without his morphia; after the second, the pain disappeared for three days, and returned (not severely) just before the third sitting; after that it passed away altogether, leaving slight discomfort after food only. As the sittings continued, even this disappeared; he was able to take solid food with comfort, his out-standing trouble, constipation, passed away, he slept well nightly, and began to gain strength and to put on flesh, and is now, three months after I began treatment, VOl. 7 eating and digesting ordinary food with ease, to all appearance in good health and weighing two stones heavier; nothing but a little weakness in the back after his long suffering and illness remaining. In any case, hypnotic suggestion has done more for him than I believe any other treatment could have done.” In 1932, Hollander reported a personal experience on relieving the pain of a cancer patient with hypnosis: “Once I was asked by a surgeon to go to a nursing home in Hampstead, where a young woman, dying from cancer of the uterus, suffered great pain which caused her to be sleepless. Within a few minutes the patient was asleep, and, in a few minutes more, wide awake with spasmodic pain. I persevered for an hour, at the end of which she seemed more peaceful. I heard no more for a week, when I received a letter thanking me for what I had done, stating that the patient had slept free from pain every night since my visit.” Rosen reported the use of hypnosis to control pain in seven patients with various conditions. He was able to obtain hypnotic anesthesia in 25 per cent of his cases. His only cancer patient was a 39-year-oldwoman with bone metastases from a carcinoma of the breast. Because of severe hip pain, uncontrolled by morphine, she was hypnotized twenty-four times during the last six weeks of life. She was undisturbed by pain during the hypnotic period, but the pain was not controlled posthypnotically. Rosen thought that a prefrontal lobotomy would have been preferred to hypnotherapy, since the patient had derived only partial relief from the latter. THE HYPOTHESIS The hypothesis that the mental and physical disturbances of the cancer patient may be favorably influenced by hypnotic suggestions evolved during thirteen years of critical investigation of hypnotic phenomena by the author. At first, over a period of six years, hypnosis was used as a tool to study psychological functions of the mind. Experience was gained in selection of suitable patients, means for allaying unfounded fears and misapprehensions, methods for inducing the hypnotic state, and procedures of elicitation of various hypnotic phenomena. Approached critically and skeptically, it was only after repeatedly reproducing the various phenomena of hypnosis that the conclusion that hypnotism is a “real” phenomenon became inescapable. No. 1 - USEOF HYPNOSIS IN CAREOF CANCER PATIENT Defined broadly, mind and body are inseparable, and, as a corollary, since hypnotism is a means of control of the mind, it can also regulate the body and its functions. With this hypothesis one can extend the use of hypnosis beyond psychological processes and apply it to the vast field of psychosomatic medicine. Exemplary of this field, seven cases of severe primary dysmenorrhea were treated. The hypnotic states were induced, painful periods were “abreacted,” and positive posthypnotic suggestions were given for the patient to be free of menstrual cramps, headaches, nausea, and vomiting. From two to twelve treatments were given at monthly intervals. Superficial psychotherapy was also utilized. Six of these cases, which were completely unamenable to all other medical therapy, were symptomatically cured to a follow-up of two to five years. Others have also found hypnotherapy effective in otherwise refractory cases.20~ 41 42 When this hypothesis is carried a step further, control of painful organic conditions should be possible. In this respect during the past six years, the author used hypnosis to facilitate the care of twenty selected obstetrical patients. Hypnosis was used successfully in relieving severe nausea and vomiting during the early months of pregnancy, in the elimination of heartburn, in alleviating back and muscular pains, and in allaying fear and anxiety. Also, at the time of labor and delivery, it was successful in partially or completely relieving the pain of the entire labor. Through the use of hypnosis, infants were delivered spontaneously, and by breech, without anesthesia. In two cases, episiotomies were made and repaired with the patient experiencing or remembering little or no pain. Postpartum, lactation could be influenced. In two cases, postpartum depression responded to positive supportive suggestions. Similar results have been obtained by others.’, 40. 41. 43, 64 The application of this same successful technique to gynecological cancer patients being cared for concurrently by the author was an unavoidable progression; for, more than any other group of patients, the cancer patients need mental-physical therapy. METHODS AND PROCEDURE Cases for this study were gradually accumulated from referrals by various physicians who thought their patients were particularly in need of and suited for this form of therapy. Butler 5 These were patients with pain and widespread cancer. Frequently, they were emotionally disturbed and had been difficult nursing problems. In these cases the usual form of medical care, including sympathetic and understanding attention and the administration of various pain-killing drugs, had not been entirely satisfactory. Also, hypnosis was suggested as a last resort before considering a prefrontal lobotomy. The patient referred for treatment was interviewed, and a detailed history was obtained with special attention to psychosomatic factors, previous impressions of hypnosis, and the present social mesh in which the patient was caught. The subject of hypnosis was forthrightly discussed, and, if the patient was co-operative, the hypnotic procedure was started. Attempts were made to have the patient in a relaxed position, either sitting or prone, in a darkened, quiet room. There was always a “disinterested” third person present. The techniques used to induce hypnosis were eye-fixation with attention focussed on a small bright light, coin, or crystal,9 hand levitation,gO*82 or lid closure with eyeball pressure by the fingertips.s Appropriate verbal suggestions were given depending on the style of induction and the personality of the patient. Soft, soothing, classical music was played on a phonograph, not only to help the patient relax but also to eliminate extraneous noise. When the operator suspected a light stage of hypnosis had been obtained, he commanded that the patient could not open his eyes. If this order was effective, progressively more complicated and more elaborate mental pictures were constructed. A floating or light feeling was usually easily obtainable, as well as epigastric warmth. Then, in sequence, extremity rigidity, “automatic” movements, visual and auditory hallucinations, and anesthesia were elicited. Posthypnotic phenomena were produced when the depth of hypnosis obtained would permit it. After the greatest depth possible was reached, pertinent suggestions were made to remove disabilities and pains, and positive commands given as demanded by the situation. When abreaction of some relevant event in the patient’s memory was indicated, this was elicited. T h e patient was then awakened. His experience was discussed with the hypnologist and superficial psychosomatic guidance was given. Narcohypnosis was used in some patients who had a superficial resistance to the usual 6 CANCER January 1954 technique of hypnotic induction. While either sodium pentothal or sodium amytal was given slowly intravenously in a very low concentration, the hypnotic techniques were followed as used in the regular patients. A state of conscibusness was maintained as much of the time as:‘possible. Some patients, following this procedure, became excellent hypnotic subjects and no longer required the drug. I n strongly resistant cases, the drug did not influence the patient, and resistance was evident even when the maximum drug was given. It appears that narcosis and hypnosis are dissimilar states, although one may aid the other when used conjointly. Narcohypnosis was not used to any great extent because of the ever-present risk of sudden respiratory or cardiac failure. The frequency of the treatments varied greatly. Out-patients were seen daily or weekly; hospitalized patients were seen at least daily and sometimes two to four times a day. Because of the amount of time required, phonograph recordings were made for specific patients on twelve-inch records at 33% r.p.m. in a recording studio. Agairi, the technique and suggestions previously found effective for that patient were specifically recorded, and effective, selected music was recorded simultaneously as a background. An automatic phonograph was placed at the patient’s bedside, and, when the patient was in a ward, the phonograph was supplied with headphones, so that adjacent patients were not disturbed. Either the patient, doctor, or nurse could start the recording; it would stop automatically. The effect of the phonograph records was usually good, but they were not so effective as personal contact with the hypnologist. Also, the patient soon memorized the record and tired of it. New records were made to combat this, and new suggestions included when indicated. Personal hypnosis was continued at intervals while the records were being used to give the patient further support. When hypnotherapy was stopped for the purpose of determining the effect of its withdrawal, if done suddenly, there was a dramatic and severe change for the worse. It was as if a prop had been knocked away. Pain became more intense, disabilities increased, and the patient was now more difficult to care for than before. If the hypnotherapy was gradually withdrawn, the patient could be maintained greatly improved without the actual use of hypnosis until that time when pain suddenly recurred or some other event demonstrated to VOl. I the patient that his course had again turned downward. Then hypnosis was used again to recover lost ground, but, each time this happened, it was more and more difficult to return the patient to the same emotional level of confidence and cheerfulness; for, each time, the “truth” became more firmly imprinted and harder to erase. I n all of this, the depth of hypnosis is the deciding factor. For practical purposes there are three stages: light, medium, and deep trance. I n a light trance, the patient recognizes some “influence” but doubts that he was hypnotized. In a medium trance, the patient is sure he was hypnotized, but he can recall freely all the events that occurred. I n a deep trance, the subject realizes that he was hypnotized, but his recall of the trance period is under the control, to some extent, of the hypnologist’s suggestions. After three one-hour periods of intensive work, cancer patients who reach only the light trance cannot be helped. Those who go into a medium trance can be helped but, the more severe and “organic” the pain, the more ephemeral the hypnotic control. Those who reach the deep or somnambulistic trance can be helped. Unfortunately these people are rare and constitute only 10 to 20 per cent of the population. Extensive disease, a distraught mind, pain, and the fear of death make induction of hypnosis more difficult than in normal people, because it seems that the most difficult thing to control under hypnosis is the function you want most to affect. The hypnologist is an important factor in this problem, for hypnosis is a transference and countertransference relationship just as is psychoanalysis. In hypnosis this interplay is not well understood by either party and is not well handled. Here, the differences in sex, age, race, and social station of the patient and the hypnologist become acutely important and may, if these factors are adverse, militate against success. Since Braid limited the role of the hypnologist and expanded the importance of the subject, there has been practically no study of the effect of hypnosis upon the hypnologist. The hypnologist is, however, affected by the treatments. He gives of himself to the patients, and he receives the discards from them. If he is in good health, comes in contact with the patient only at intervals, and takes his work lightly, he will be unaware of this, and there will be little affect. If the reverse is true, however, he will gradually feel his vitality become reduced and No. 1 USEOF HYPNOSIS IN CAREOF CANCER PATIENT - Butler will become more susceptible to illness himself. Even an hour’s treatment with a very sick patient can produce an appreciable tiring of the hypnologist, and, as the sympathetic bond between the two grows stronger, the hypnologist may even “feel” the symptoms he is trying to eradicate from the patient. W. L. Howard also found that the effect upon the operator may be “very severe,” and that, when the hypnotic treatments are “continually kept up on several cases without mental rest, it may produce some very injurious conditions” in the operator. William Davey advised, “If the operator labours under any deficiency of healthful vigour, the frequent contact with diseased individuals will be sure, by the law of mesmeric sympathy, to affect him with pains and disquietudes, if not perfectly analogous to those of his patients, yet bearing such relationship to them, as will suffice to make him painfully conscious of the source whence they are derived.” However, with an expenditure of considerable time, energy, and ingenuity, a very sick suffering patient may live his last months of life with a minimum of drugs, a sense of hopefulness and cheerfulness, and relative freedom from pain. His mind becomes more acute rather than dulled, as with drugs. The rest of his body functions as well as it can without being further inhibited by drug side-action. He is a rational thinking human until death, rather than a “vegetating” invalid as may happen after a prefrontal lobotomy. He has been supported in the last days of his life by the compassion of his physician rather than let down with drug addiction and destructive surgery. I n summary we have the mind of the patient struggling for survival, aided by the mental support of the hypnologist; both are fighting a losing battle, for, in the end, cancer and death will win. 7 the second attempt that there was complete loss of the corneal reflex, loss of sensation to painful stimuli, and complete amnesia to the entire trance period. She was a somnambulist. On the third day, it was decided that the diagnosis must be confirmed, and then an ex. ploratory operation was indicated. Since the patient was in a poor physical condition, hyp nosis was suggested as the form of anesthesia. Again the patient was placed in a deep trance. After two hours, when she had lost the corneal reflex but still carried out suggestions, she was taken to the operating room. T h e abdomen was prepared and draped, and, with no other form of analgesia or anesthesia except hypnosis, an incision 10 in. long was made from the umbilicus to the symphysis pubis. Skin towels were applied, and the incision was carried down to the fascia through 3 to 4 ,in. of subcutaneous fat. As the fascia was being incised, the patient moved but did not complain of pain. With this, however, cyclopropane anesthesia was started, and without waiting the exploration was continued. Carcinomatosis was found; the ovarian tumor was biopsied, and the incision closed. Postoperatively, the patient stated that she had felt no pain at any time; however, she also had no memory concerning the period of time during which she was hypnotized. Her physical condition then deteriorated rapidly, and she died three days later. Since she had no further severe pain, hypnosis was not used after the operation. Case 2. Mrs. M. R., age 48, was admitted to the hospital because of a tumor the size of a six-month pregnancy that filled the pelvis and lower abdomen. It was a rapidly growing sarcoma of the uterus. The patient was in severe pain. It required the assistance of three people to move her in bed, for movement made the pain more acutely excruciating. She had been bedridden for six weeks and was anorexic and constipated. Consequently, she was depressed, frightened, and morbid. She suspected that she was dying of cancer. With the first attempt at induction she entered a deep somnambulistic trance. It was CASEHISTORIES suggested that she was free of pain, fear, and anxiety. She was told to get out of bed and Case 1. Mrs. M. B., age 55, received mor- walk. This she did with but little support. phine, 15 mg., every four hours for relief of When she was awakened and told of her proglower abdominal pain. The tentative diagnosis ress, it seemed incredible to her. Actually she on admission was carcinoma of the ovary with was free of pain and could move in bed easily. metastasis. A hypnotic state was induced easily She ate better than she had in weeks and slept during which suggestions were made for the without medication. patient to be free of pain and to become calm During the next three weeks, the patient was and relaxed. After the second treatment her kept in a hypnotic state 30 to 40 per cent of pain was improved, and she required one half the time, and she found that she could take of her usual amount of morphine to keep her food and control her bowel elimination by givfree of pain. She was so deeply entranced on ing herself suggestions. She was able to get out 8 CANCER January 1954 of bed alone and to walk unaided; also, sht was eating well. She required no analgesic agent. She had a particular dread of her daily trip to the radiotherapy department. Since she would stay in a trance two to three hours without waking, she was hypnotized in her room and told not to awaken until after she had returned from her treatment. Thereby, she had no memory of this experience and, hence, no dread. It is pertinent to state that the tumor grew rapidly in spite of radiotherapy. When hypnosis was discontinued, but the same amount of personal attention to the patient was maintained, the patient did well for thirty-six to forty-eight hours; then she would gradually slip back into her previous condition. She would con,,Aain of severe abdominal pain and weakness, be unable to get out of bed, and have again a strong fear of dying. Then, with as little as five minutes of hypnosis with appropriate suggestions, she would awaken free of pain, strong, and liberated from anguish. By the end of the second month, a phonograph record was made from a tape-recording of a hypnotic treatment at the patient’s bedside. T h e record was then available for the patient to play on a portable phonograph in her room. This record, at first, induced a deep state of hypnosis, but later, as the patient memorized the words, she became annoyed with it, and it became less effective. Then other records were made for specific uses: to induce sleep, to relieve pain, to restore calmness and confidence. By using a variety of records, the patient was maintained and required personal hypnosis only once a day. By the end of the third month of hypnotic treatment, the tumor had grown to the size of a term pregnancy. T h e bowel was partially obstructed and vomiting became difficult to control. T h e records were not effective, and the patient was kept in a trance most of the time by personal hypnosis. Even when the tumor ruptured and drained a copious foul necrotic material out of the vagina, the excruciating pain was quickly relieved by inducing a deep trance. Soon after this the patient died. Case 3. Mrs. I. M. was a 65-year-old actress and dramatic coach, who had had a radical mastectomy two years previously because of cancer of the breast. She complained of pain in the occipital portion of her head that radiated down both arms. Her right arm was weak, so that she could no longer lift a glass or cup. She could not write, and she was incapacitated by the pain so that she could not teach. Roentgen-ray examination disclosed that she had metastatic lesions in the cervical vertebrae, ribs, ischiurn, a n d right femur. Radiotherapy had Vol. 7 been given to the cervical region without relief of pain. Over a period of two weeks the patient was hypnotized ten times. She entered the somnambulistic stage and could be made anesthetic to painful stimuli. During this period she was able to get out of bed and walk unassisted. Her pain became less and she regained the use of her right arm so that she could lift a pitcher filled with water and could write. She regained her courage. When she was in the hospital she used a record to help her at night. At the end of this time she returned to her studio and actively taught dramatics again. No further hypnotherapy was used. One month later, however, the pain returned and the patient had to be readmitted to the hospital. Finally, a prefrontal lobotomy was performed on the right side of the brain, but, when the pain continued unabated, in fact was even more severe, hypnotherapy was tried again. Now, five months after the first successful use of hypnosis and one month after the lobotomy, the patient had a clear sensorium and a good memory, but it was difficult for her to concentrate. She complained of severe pain in her right thigh, where she had a pathological fracture of the femur, a severe pain over the left side of her head, and a heaviness of her face. Pain had become so severe that she required morphine every four hours. Hypnotic techniques were used, but she was now very sick and debilitated. She said that she wanted to die and resisted my suggestions. Also, since she had had the lobotomy, concentration was difficult. Only a medium trance could be induced and that required great effort and time. After five long sessions over a period of eight days, there was subjective improvement. T h e phonograph and recordings were used at night. Pain became less and appetite returned. There was some improvement because of the hypnotic treatments, but it was neither striking nor dramatic. Soon after this the right hip was nailed, her condition became rapidly worse, and she died. It is worthy to note, first, that this woman who was very intelligent, independent, resourceful, and successful, found it difficult to adjust to a dependent role. Also, there was a certain sense of persecution about her pain, which came in “spasms” and which she associated with “people coming after her.” She believed her present suffering was a punishment for her inconsideration of others during her life. Prefrontal lobotomy in this patient interfered with the hypnotic state because concentration was more difficult. No. 1 USEOF HYPNOSIS IN CARE OF CANCER PATIENT Case 4. G. P. was a 14-year-oldboy who had acute myelogenous leukemia. He was referred for treatment because of severe pain in the coccyx, depression, apathy, and anorexia. He was anemic and had responded poorly to transfusions. This boy was interviewed and hypnotized six times over a period of one week. On two occasions he was in a somnambulistic trance and on the other four reached only a medium trance. Nevertheless, his pain was entirely relieved while under hypnosis, although it would return three to six hours after the treatment. He became congenial, his appetite returned, and he felt a return of his normal vigor. Actually, his hemoglobin increased 1.0 gm.during this period, although he received no transfusions, and, by the end of the week, he required no medication for pain. Six days after this a perirectal abscess was discovered as the cause of the coccygeal pain and, following incision and drainage, there was continued subjective improvement. The patient left the hospital and returned home. He did well on supportive therapy. Four months later, he inadvertently read a letter that disclosed to him the lethal nature of his disease. A relapse immediately followed this experience, and he was readmitted to the hospital. He died eight weeks later. Hypnotherapy was not used during this last admission. Case 5. Mrs. I. R. was a 72-year-old colored woman, who had a carcinoma of the right parotid gland, which had been treated with radiotherapy during the past year. As a result her face was distorted by a seventh nerve paralysis, and, from the onset of the radiotherapy, she had a bad taste in her mouth. She was troubled mostly, however, by excessive salivation that had not responded to any type of treatment and by the anorexia related to these disturbing symptoms. She also had pain in the right side of her face and neck. In addition she was confined to bed or a wheelchair for the past month owing to deformity of her legs by rheumatoid arthritis. The patient would enter a medium trance and, during one week when she was seen six times, the bad taste, face pain, and excessive salivation were controlled during the hypnotic period and for as long as twenty-four hours posthypnotically. First, while in a trance, and then, when entirely awake, the patient was ambulated, and by the end of the week she was walking around the ward unassisted. Her appetite improved &d she ate well as long as her symptoms were under control. Hypnotherapy was stopped and all her symptoms returned. Three weeks later a prefrontal lobotomy was performed on the right side, but following this - Butler 9 there was no improvement. T h e patient was very weak and bedridden. Two weeks later hypnotherapy was tried again. Although difficult to evaluate because of a mental lethargy and dullness, it was possible to elicit a few hypnotic phenomena during two interviews. T h e depth of hypnosis, however, was definitely not so great as had been obtained before the lobotomy had been performed, and the efficacy of the treatment was doubtful. Because of the patient’s poor condition further attempts a t hypnosis were not tried. She died ten days later. Case 6. E. B. was a 49-year-old man with secondary carcinoma of the liver. T h e primary site was unknown. He was jaundiced, the liver reached the iliac crests, and he was unable to eat. Hypnotherapy was utilized in an attempt to combat the anorexia. After five interviews during one week only, a medium trance could be induced. However, a definite and prolonged improvement in his appetite occurred with a consumption of a greater amount of food than previously. Real hunger could also be suggested. After therapv was stopped, the anorexia returned, and threc weeks later the atient left the hospital. He died at the end o ten weeks. F Case 7. Mr. M. R. was a 72-year-old Hungarian, who had had a carcinoma of the right breast removed twenty years previously. He was admitted because of a three-month history of intractable pain in his right hip, thigh, knee, and to some extent where his right leg had been (his right leg had been amputated below the knee during World War I, because of injuries and subsequent infection). Neurological examination failed to reveal any abnormality and there were significant emotional factors in his background. For these reasons hypnotherapy was suggested. He was a translator of scientific articles, had been a teacher of natural sciences, and, when he lived in Vienna, hypnosis was a new development used in the detection of crime and in the treatment of shell shock. Although he was fearful of being hypnotized, he quickly entered a deep trance and was made to relive his past life, which he described in German. In doing so he re-experienced pain in his right extremity and abreacted the appropriate emotional concomitants-a phenomenon like the “crises” described by Mesmer. Following this the patient was awakened. His pain had disappeared. The next day he said he felt as though “his body and soul had been torn apart,” and that he remembered people he had not seen for decades. Although he continued to complain of pain in his thigh, it was not severe and in no way did it affect his sleeping. He refused fur- 10 CANCER .January 1954 ther hypnosis, and a contemplated neurosurgical operation was decided not to be indicated. He left the hospital two weeks later and did not return for follow-up. VOl. 7 CASES SEEN O N A N OUT-PATIENT BASIS Case 10. Mrs. J. B., age 35, was seen weekly over a period of two and a half months. Two years previously she had had a radical mastecCase 8. H. J. was a 50-year-oldman who had tomy on the right for carcinoma. She then dehad a radical removal of a malignant testicular veloped an inflammatory carcinoma of the left tumor nine months previously. Following this, breast with secondary metastases of the lung. extensive radiotherapy was given to his abdo- There was considerable unrest at home because men and lower back. For the past four months, of a 3-year-old daughter, religious differences, he has had low-back and bilateral leg pain; and a difficult, demanding husband. She comfor two months, spasms of the lower abdomen plained mainly of a burning pain and a tight and legs shook the patient rhythmically and feeling over her right chest, which accompanied spasmodically day and night. An electromyo- anxiety states precipitated by arguments at gram demonstrated forty regular spasms per home. She frequently had terrifying dreams minute. A myelogram and roentgenograms re- and her sleep was disturbed by protracted perivealed no evidence of a metastatic tumor. ods of coughing. The patient said on his first interview, “The A medium trance could be induced, and by only time I’ve been free of pain in the past four suggestion her anxiety and fear could be lessmonths was when my mind didn’t know it.” ened. Her chest pain and cough, however, When only a medium trance could he obtained showed little response. When she went home, after three attempts at hypnosis, intravenous the arguments and disagreements that ensued sodium amytal was combined with the hyp- negated these effects quickly; hypnotherapy notic procedure. During this interview it was was stopped and she died two months later. learned how he had been affected by the sufferCase II. Mr. A. M. was a 55-year-old man ing of his father, who had died of cancer a few years previously. His father had had severe who had had a carcinoma of the right lung leg pains comparable to the patient’s. The partially removed by pneumonectomy five patient had also tried to get some drug to put months previously. He ascribed his illness to a his father “out of his misery,” but, before he blow on the chest while boxing twenty years could accomplish this act, his father died. ago. The patient was a food fadist and came to There was considerable expression of feeling the hospital for weekly visits, stooped over and about this by the patient. The parallelism he complaining of severe chest pain. A medium had made between himself and his father, as trance was induced on three separate interwell as his self-imposed punishment, was views. When awakened, the patient would cry pointed out to him. During this interview the and claim that he was finally free of pain. He lower abdominal and leg spasms stopped com- would leave the hospital walking straight and pletely, and following it the patient said that smiling, but, by the time he had taken an he felt “at peace with the world,” and “his legs hour’s subway ride home, he was in pain again. were absolutely quiet for the first time in He died six weeks later. three months.” A similar result followed a Case 12. Mrs. B. L. was a 46-year-oldwoman second interview of narcohypnosis and in a few days the patient was discharged from the hos- who had had a carcinoma of the left breast removed locally and treated with radiotherapy pital 90 per cent improved. Not long after returning home where family, fifteen years ago. Eight years ago she had a rerelatives, and well-meaning friends gave him currence and finally submitted to a radical consolation, his spasms and pains returned mastectomy but she would not permit further radiotherapy. She noticed a lump in the right with even greater severity. axilla four years ago, which has continued to Case 9. Mrs. E. S. was a 52-year-old colored grow slowly, and she has gradually been diswoman with a stage-IV carcinoma of the cervix. turbed by pain and swelling of her right arm. Weekly cervical biopsies were taken for a re- This area was again treated with radiotherapy. When seen for the first time for hypnothersearch study until the patient became so afraid of the pain of the procedure she would not apy, the patient had been having pain for five permit it. Hypnosis was induced and a medium months and was taking 60 mg. of codeine every trance with partial skin anesthesia was ob- four to six hours. She was seen twice a week tained. The cervical biopsy was taken easily. for seven weeks. She entered only a medium The next week, the patient resisted being hyp- trance state, but her axillary and arm pains notized, but in spite of this the biopsy was could be relieved while entranced. During this taken in a medium trance. The third week it entire time, she became less anxious, her pain was impossible to induce a hypnotic state and lessened, and for twenty-four hours after an interview her drug requirement was reduced. the biopsy could not be taken. No. 1 USEOF HYPNOSIS I N CAREOF CANCER PATIENT Butler * 11 lized by a physician in the care of someone who had a longer life expectancy. At least, in order to gain maximum relief for the time spent, one should select patients who enter’a deep or somnambulistic trance, for in these patients organic pain and subjective symptoms can be‘ relieved, and through posthypnotic suggestions relief may be continued after the period of hypnosis. Phonograph recordings are of definite value in this respect, but specificity, flexibility, and variety of suggested mental pictures and musical background must be kept constantly in mind. T h e results of this study would not indicate that further efforts should be made to expand this type of therapy. However, there are two aspects of it that are obscure but, nevertheless, very important. The first is the intuitive knowledge gained by intimate association with these patients that there is a cancer personality. It is intangible and from this small experience difficult to delineate in distinctive features, but nevertheless it is a possibility worthy of further DISCUSSION investigation. A rough sketch of this personalHypnosis is an altered state of mind. Philos- ity reveals an individual who fails to express ophers, theologians, and scientists cannot ade- himself; who represses hate, anger, dissatisfacquately explain what mind is, and therefore tions, and grudges; or, on the other hand, is a hypnosis, which is a state of ,mind, also remains very “good“ person, who is consumed with selfan enigma. T o describe it as a neurosis,sl a pity and suffers in stoic silence. T h e future of state of hypersuggeslibility,ll* 36 a period of cancer could lie in the psychosomatic approach, dissociation of the brain,47 a type of condi- and the precancerous personality might be tioned reflex,60 or a hysteria19 does not take treated with psychological means. I n this study into account the facts we know about it. Let us of personality, one should inquire into the psycall hypnosis that state of mind in which phe- chodynamic basis for pain, for, of two patients nomena described as hypnotic occur. with apparently equal metastatic spread of Hypnotic techniques as used. in this study disease, one will have pain and the other will did reduce pain, allay anxiety, and aid in organ not. ‘One factor demonstrated in these cases function; but the results were proportional to was the influence of a sense of guilt and of a the depth, and only five of these selected twelve need for punishment. Disease and death were cases, who were somnambulistic, can be said not adequate retribution for the unconscious to be unequivocally benefited by this therapy. impulse to kill, to lead an immoral life, or to The remainder of the patients who could enter compensate for the lack of kindness to others. a medium trance were helped, but it is doubt- It was necessary to add pain to balance the ful if this improvement is adequate compensa- moral budget. tion for the time spent to obtain it. Certainly, The second important finding is not the pracan out-patient basis is not satisfactory if the tical therapeutic aspect of emotional control, patient is in as much distress on returning pain elimination, and organic function by home as when he left it. means of “words,” but rather fundamental and T h e great amount of time and energy, pa- basic evaluation of the fact that by “controlled tience, and ingenuity required of the hypnolo- thoughts” alone these things are possible. gist to produce these results has not been adeElectricity and mesmerism were discovered quately emphasized, for herein lies the chief and condemned respectively by Benjamin defect in th& procedure. Certainly, we want Franklin. Electricity has been made the servant each person to end his life with as little suffer- of man, while our understanding of hypnotism ing as possible, but from a practical point of has not advanced; in fact, there are reasons to view this same energy and time could be uti- suspect that Mesmer knew more about it than Deeply rooted obsessional neuroses that prevented her from riding in a car, walking alone on the street, and visiting friends were resolved by hypnotic suggestion. Besides the interviews, the patient was relieved of two attacks of acute anxiety and pain through the use of hypnosis over the telephone. Hypnotherapy was stopped and, within a few days, the patient regressed to her former state. Then her mother died. Immediately she became worse and again had excruciating pains. Codeine was no longer adequate and she required 10 to 20 mg. of morphine sulfate every four hours. T.hree and one-half months after hypnotherapy had been stopped, the patient was seen again. Only a medium trance could be induced; pain was relieved during the trance but recurred quickly afterward. However, again her fears and anxieties were quickly and effectively brought under control. The possibility of living six months, however, precluded the use of hypnosis for this length of time and a chordotomy was advised. 12 CANCER January 1954 he conveyed in his writings, and there is available scientific evidence to support Mesmer’s original contentions or propositions. If we knew fundamentally how the mind could eliminate pain, then possibly this knowledge could be used, freed from the disadvantages that now surround hypnotism. Our present-day knowledge of hypnosis does not elucidate or consider the role of the hypnologist. He might as well be a flashing light or a phonograph record, but this does not explain how hypnosis affects him deleteriously. Possibly he is imperceptibly hypnotized himself and identifies himself so closely with the patient that, without his knowledge, he “becomes the patient” and after the treatment feels the negative affect he has been trying to remove with positive suggestions. It may later be proved that this results from a mesmeric influence. However, if self-analysis may be credited, there is this side of the problem of which anyone who engages in hypnosis with very sick patients must be cognizant. The suggestion that hypnosis is a “psychological” prefrontal lobotomyw has no basis in fact. At least in the cases reported here in which hypnosis was tried before and after lobotomy, hypnotizability was roughly directly proportional to the remaining ability to concentrate and inversely proportional to the completeness of the operation. It did not make the patient more easily hypnotized, as it should if it were a surgical and permanent form of the same state of mind. Hypnotism is not to be considered lightly, for as Sir William Osle96 said, “It is a twoedged sword, and needs careful handling.” Its use must be restricted and it is safest in the hands of the competent psychiatrist, who has had a particular interest and experience with it. Other specialists and general practitioners should use it only after adequate training, and then only when other methods available are inadequate. The use of hypnotism can be compared to the performance of a difficult operation. Anyone can cut the skin, many may remove an appendix, but who should remove a stomach, a pancreas, or a lung? The same is true of hypnosis-anyone can learn to induce it, some can get therapeutic results, but only those with experience and training should attempt to cut out pieces of mind. Vol. 7 CONCLUSIONS 1. Pain, anxiety, and organ dysfunction in the cancer patient can be aided by the intensive use of hypnotherapy. The results are proportional to the depth of trance and the efficiency of the program of therapy employed. 2. Patients who easily enter a deep trance can be helped; those who reach only a medium state can be aided, although the more “organic” the complaints, the more ephemeral the response; while patients who, after repeated trials, can only enter a light stage cannot be helped by this means. 3. The main disadvantages of this form of therapy are the few good subjects, the large amount of time required, and the necessity of an experienced and well-trained hypnologist to govern each case. The possible deleterious etfect upon the health of the hypnologist and the long period of time required for one patient between onset of symptoms and death, thus limit the number of patients a single therapist could manage. Then, too, public resistance to hypnosis persists. 4. The advantages of hypnotherapy for patients who enter a deep trance are numerous. Drug requirements are lessened, pain is relieved, organ dysfunction can be corrected as much as possible, and depression, anxiety, and fear are minimized. Life is prolonged and death is approached as is a night’s sleep. 5. Prefrontal lobotomy interferes with the induction of the hypnotic state in proportion to the decreased ability of the patient to concentrate and, therefore, appears to be different from the hypnotic state. 6. Narcohypnosis helps to counteract superficial resistance but does not appear to aid otherwise in obtaining greater true hypnotic depth. It does not eliminate all resistance. 7. Future efforts should be expended to learn what hypnosis is and how i t alters physiological function. When these fundamentals are understood, its advantages will have a wider and more satisfactory application. 8. There may be a “cancer personality.” From a very intensive study of these cases, either an irihibited individual with repressed anger, hatred, and jealousy or a “good” person consumed with self-pity may be prototypes of this personality. No. 1 USEOF HYPNOSIS IN CAREOF CANCER PATIENT - Butler 13 REFERENCES 1. ABRAMSON, M., and HERON,W. T.: An objective evaluation of hypnosis in obstetrics; preliminary report. Am. J. Obst. 6 Gynec. 59: 1069-1074, 1950. 2. ALEXANDER, F.: Emotional factors i n essential hypertension; presentation of a tentative hypothesis. Psychosom. Med. 1: 173-179, 1939. 3. ALEXANDER, F.: Psychological aspects of medicine. Psychosom. Med. 1: 7-18, 1939. 4. ALEXANDER, F.: Sigmund Freud: 1856-1939.Psychosom. Med. 2: 68-73,1940. 5. ALEXANDER, F.: Psychosomatic Medicine; Its Principles and Applications. New York. W. W. Norton & Co. 1950. R. K.: Some aspects of the treatment of 6. AXELRAD, the emotional problems of the tuberculous. News-Letter Am. A . Psychiatric Social Workers 15: 81-84, 1946. 7. BERNHEIM, H.: Suggestive Therapeutics; a Treatise on the Nature and Uses of Hypnotism. (Transl. from 2d French ed. by S. A. Herter.) G. P. Putnam's Sons. 1900. 8. BINET,A., and F k ~ iC.: , Animal Magnetism, 2d ed. London. Kegan Paul, Trench & Co. 1888. J.: Neurypnology or, the Rationale of Nerv9. BRAID, ous Sleep, Considered in Relation with Animal Magnetism. London. John Churchill. 1843. 10. BRENMAN, M.: Experiments in the hypnotic production of anti-social and self-injurious behavior. Psychiatry 5: 49-61, 1942. 11. BRENMAN, M., and GILL, M. M.: Hypnotherapy, a Survey of the Literature. New York. International Universities Press. 1947. A.: T h e Invisible Influence; a Story of 12. CANNON, the Mystic Orient with Great Truths which Can Never Die. New York. E. P. Dutton & Co., Inc. 1934. 13. CARTWRICHT, F. F.: T h e English Pioneers of Anaesthesia. Bristol. John Wright & Sons, Ltd. 1952. J. M.: Clinical Lectures on Diseases of 14. CHARCOT, the Nervous System, Vol. 3. (Transl. by Savill.) London. New Sydenham Society. 1889. J.: Human Magnetism: or How to Hyp15. COATES, notise, a Practical Handbook for Students of Mesmerism. London. George Redway. 1897. 16. DANIELS, G. E.: Practical aspects of psychiatric management in psychosomatic problems. New York J. Med. 41: 1727-1732, 1941. 17. DANIELS, G. E.: Psychiatric factors in ulcerative colitis. Gastroenterology 10: 59-62, 1948. 18. DAVEY, W.: T h e Illustrated Practical Mesmerist; Curative and Scientific, 2d ed. Edinburgh. MacLachlan & Stewart. 1856. 19. DE ST. DOMINIQUE, C.: Animal Magnetism (Mesmerism) and Artificial Somnambulism: Being a Complete and Practical Treatise on That Science, and Its Application to Medical Purposes. Followed by Observations on the AffinityExisting Between Magnetism and Spiritualism Ancient and Modern. London. Tinsley Brothers. 1874. 20. DICK.W.: Die Dsvchische Form der Dvsmenorrhiie und deren' hypnotis'hk Behandlung. Arch. f. Gynak. 124: 345-366, 1925. 21. DIDIER,A.: Animal Magnetism and Somnambulism. London. T.C..Newby. 1856. 22. DUNBAR, H. F.: Emotions and Bodily Changes; a Survey of Literature on Psychosomatic Interrelationships 1910-1933. 2d ed. New York. Columbia University Press. 1938. J. B.: An experimental study in hypnotic 23. DYNES, anesthesia. J . Abnorm. 6 Social Psychol. 27: 79-88, 1932. J.: Numemus Cases of Surgical Op24. ELLIOTSON. erations Without Pain in the Mesmeric State with Remarks upon the Opposition of Many Members of the Royal Medical and Chirurgical Society and Others to the Reception of the Inestimable Blessings of Mesmerism. London. Lee & Blanchard. 1843. 25. ERICKSON. M. H.: An experimental investigation of t h e possible anti-social use; of hypnosis. P s y c h t r y 2: 391-414, 1939. J .: Mesmerism in India; and its Practical 26. ESDAILE, Application in Surgery and Medicine. Chicago. Psychic Research Co. 1902. 27. FELKIN,R. W.: Hypnotism or Psycho-Therapeutics. Edinburgh. Young J. Pentland. 1890. 28. FORD,W. L., and YEAGER,C. L.: Changes in the electroencephalogram in subjects under hypnosis. Dis. N e w . System 9: 190-192, 1948. 29. FOREL,A.: Hypnotism; or Suggestion and Psychotherapy; a Study of the Psychological Psycho-physiological and Therapeutic Aspects of Hypnotism. (Transl. from 5th German ed. by H. W. Armit.) New York. Allied Publications. 1949. 30. FRANKAU, G.: Introductory Monograph. I n Mesmer, F. A.: Mesmerism. London. MacDonald. 1948. 31. GALICIA,J. C.: T h e psychogenesis of hypnotic suggestion; a survey and critical commentary. Brit. J . Med. Hypnotism 4(2): 2-13, 1952. 32. GRINKER, R. R., and SPIEGEL, J. P.: War Neurosis in North Africa; the Tunisian Campaign (January-May 1943). New York. Josiah Macy, Jr. Foundation. 1943. 33. HOLLANDER, B.: Hypnosis and anesthesia. Proc. Roy. SOC. Med. 25: 597-610, 1932. J. S.: Narco-analysis; a New Technique 34. HORSLEY, in Short-cut Psychotherapy: a Comparison with Other Methods: and Notes on the Barbiturates. London. Oxford University Press. 1943. 35. HOWARD,W. L.: Hypnotism as a therapeutic agent. Tr. M. SOC. Virginia 23: 71-85, 1892. 36. HULL,C. L.: Hypnosis and Suggestibility: an Experimental Approach. New York. D. Appleton-Century Co. 1933. 37. HUNT,J. R.: Nature and treatment of psychic. and emotional factors in disease. J. A. M. A. 89: 10141017, 1927. 38. HUSE,B.: Does the hypnotic trance favor the recall of faint memories? J. Exper. Psychol. 13: 519-629, 1930. A.. and WIBLE.C. L.: Remiration and 39. IENNESS. heart &ion i n sleep and hypnosis. J. Gen.' Psychol. 16: 197-222, 1937. 40. KROGER, W. S., and DE LEE, S. T.: The use o f the hypnoidal state as an amnesic, analgesic and anesthetic agent in obstetrics. Am. J. Obst. & Gynec. 46: 655-661, 1943. W. S., and DE LEE,S. T.: T h e psychoso41. KROGER, matic treatment of hyperemesis gravidarum by hypnosis. Am. J. Obst. 6 Cynec. 51: 544-552, 1946. W. S., and FREED,S. C.: T h e psychoso42. KROCER, matic treatment of functional dysmenorrhea by hypnosis. A m . J. Obst. Q Gynec. 46: 817-822, 1943. W. S., and FREED,S. C.: Psychosomatic 43. KROCER, Gynecology: Including Problems of Obstetrical Care. Philadelphia. W. B. Saunders Co. 1951. 44. LIPKIN,M.; MCDEVI~T. E.; SCRWARTZ, M. S., and DURYEE, A. W.:On the effects of suggestion in the treatment of vases astic disorders of the extremities. psy. 152-157. 1945. chosom. Med. A. B., and JOHNSTON, R. L.: T h e 45. LUCKHARDT, psychic secretion of gastric juice under hypnosis. Am. J. Physiol. 70: 174-182, 1924. 46. LUNDHOLM. H.,and LBWENBACH, H.: Hypnosis 5: 14 CANCER January 1954 Vol. 7 65. SAMUEL, H. L.: Essay in Physics. New York. Harand the alpha activity of the electroencephalogram. court, Brace & Co.. Inc. 1952. Char. 6 Personal. 11: 145-149, 1942. 66. SEARS, R. R.: An experimental stud of hypnotic 47. MCDOUCALL, W.: Outline of Abnormal Psycholanesthesia. J . Exper. Psychol. 15: 1-22, 19 2. ogy. New York. Charles Scribner’s Sons. 1926. 67. SHAKESPEARE, W.: The Tragedy of Hamlet, Act 3, K.: Emotional factors in hyperten48. MENNINGER, Scene 1. London. Oxford University Press. 1938. sion. Bull. New York Acad. Med. 14: 198-211. 1938. J. E.: COBB,S., and 68. SHANDS, H. C.; FINESINGER. F.: 49. MEYER, A.: BOLLMEIER, L. N., and ALEXANDER, R. D.: Psychological mechanisms in patients Correlation between emotions and carbohydrate metab- ABRAMS, olism in two cases of diabetes mellitus. Psychosom. Med. with cancer. Cancer 4: 1159-1170, 1951. 7: 335-341. 1945. 69. SIRNA,A. A.: An electroencephalographic study 50. MILLER,H. C.: Hypnotism and Disease; a Plea of the hypnotic dream. J . Psychol. 20: 109-113, 1945. for Rational Psychotherapy. Boston. Gorham Press. 70. STRICKLER, C. B.: A quantitative study of post1912. hypnotic amnesia. J . Abnorm. & Social Psychol. 24: 10851. MITTLEMANN, B., and WOLFF,H. G.: Emotions 119, 1929. and gastroduodenal function; experimental studies on 71. SUCRUE, T.: There Is a River; the Story of Edgar patients with gastritis, duodenitis and peptic ulcer. Cayce. New York. Henry Holt & Co. 1943. Psychosom. Med. 4: 5-61, 1942. 72. TESTE,A.: A Practical Manual of Animal Mag52. MOLL,A.: Hypnotism: Including a Study of the netism: Containing an Exposition of the Methods EmChief Points of Psycho-therapeutics and Occultism. ployed in Producing the Magnetic Phenomena: with its (Transl. from 4th German ed. by A. F. Hopkirk.) Lon- Application to the Treatment and Cure of Diseases. don. Walter Scott Pub. Co. Ltd. 1909. (Transl. from 2d French ed. by D. Spillan.) London. 53. NEWBOLD, G.: Famous names in hypnotism: (1) H. Bailliere. 1843. Franz Anton Mesmer (1733-1815). Brit. J . Med. HypA. J.: A Study of History. (Abridgement 73. TOYNBEE, notism l(2): 3-8, 1949. of Vol. I-VI by D. C. Somervell.) London. Oxford Uni54. NEWBOLD, G.: T h e use of hypnosis in obstetrics. versity Press. 1947. Brit. J . Med. Hypnotism l(1): 36-38, 1949. C. L.: Psycho-therapeutics: or, Treat74. TUCKEY, 55. NEWBOLD, G.: Famous names in hypnotism; (2) ment by Hypnotism and Suggestion, 3d ed. New York. C. P. Putnam’s Sons. 1892. John Elliotson (1791-1868). Brit. J . Med. Hypnbtisni l(3): 2-7, 1950. F. A.: James Braid’s discoveries and 75. VOLGYESI, 56. NEWBOLD, G.: Famous names in hypnotism; (4) psychotherapeutic merits. Med. Zllus. 3: 217-222, 1949. Antoine Likbeault (1823-1904). Brit. J . Med. Hypnotism 76. WALDEN, E. C.: A plethysmographic study of the 3(3): 2-7, 1952. vascular condition during hypnotic sleep. A m . J . Physiol. 57. NICHOLSON, N. C.: Notes on muscular work dur- 4: 124-161, 1900. ing hypnosis. Bull. Johns Hopkins Hosp. 31: 89-91,1920. 77. WATKINS, J. G.:Antisocial compulsions induced 58. PACHTER, H. M.: Paracelsus; Magic into Science. under hypnotic trance. J . Abnorm. & Social Psychol. 42: 256-259, 1949. New York. Henry Schuman, Inc. 1951. 0.S.: Psychosomatic Med78. WEISS,E., and ENGLISH, 59. PAT~IE,F. A., JR.: T h e genuineness of hypnotically produced anesthesia of the skin. A m . J . Pyschol. icine; the Clinical Application of Psychopathology to General Medical Problems, 2d ed. Philadelphia. W. B. 49: 435-443, 1937. 60. PAVLOV, I. P.: Conditioned Reflexes: an Investi- Saunders Co. 1949. 79. WEITZENHOFFER, A. M.: T h e production of antigation of the Physiological Activities of the Cerebral Cortex. (Transl. by G. V. Anrep.) London. Oxford Uni- social acts under hypnosis. J. Abnorm. 6 Social Psychol. 44: 420-422, 1941. versity Press. 1927. 80. WELLS,W. R.: Experiments in the hypnotic pro61. PYNE,T.: Vital Magnetism: a Remedy. London. duction of crime. J . Psychol. 11: 63-102, 1941. Samuel Highley. 1845. 81. WILLIAMS, G. W.: The effect of hypnosis on mus62. ROBINSON, V.: Victory Over Pain; a History of cular fatigue. J . Abnorm. & Social Psychol. 24: 318-329, Anesthesia. New York. Henry Schuman, Inc. 1946. 1929. 63. ROSEN,H.: T h e hypnotic and hypnotherapeutic L. R.: Medical Hypnosis: the Princi82. WOLBERG, control of severe pain. A m . J. Psychiat. 107: 917-925, ples of Hypnotherapy. New York. Grune & Stratton, Inc. 1951. 64. ROWLAND. L. W.: Will hvmotized Dersons trv to 1948. 83. ZINSSER, H.: As I Remember Him: the Biography harm themselves or others? J. ATnorm. & Social Psyihol. 34: 114-117, 1939. of R. S. Boston. Little, Brown and Co. 1940. 3
© Copyright 2026 Paperzz