11/28/2011 Callous-Unemotional Traits and Developmental Pathways to Violent Behavior in Children and Adolescents DSM-IV Criteria for Conduct Disorder American Psychiatric Association, 1994 Aggression to people and animals Paul J. Frick, Ph.D. University Distinguished Professor Chair, Department of Psychology University of New Orleans Destruction of property Deceitfulness or theft E-mail: [email protected] Web: http://www.psyc.uno.edu/Frick%20Lab/Home.html Childhood-Onset Conduct Disorder Serious violations of rules Runs away from home overnight Truancy Childhood-Onset Conduct Disorder Adult (age 26) Outcome Cruel to Others, Stealing, Running Away from Home, Truancy, Breaking and Entering, Assault Lies, Physical Fights Bullies, Cruel to Animals, Breaks Rules Stubborn, Defies Adults, NonCompliant, Temper Tantrums, Argumentative, Annoys Others 14 13 12 11 10 9 8 7 6 5 4 3 60 50 A G E 40 30 20 10 0 Any Adult Convictions No CP (n=233) Violent Convictions Childhood‐onset (n=42) Adolescent‐onset (n=119) Source: Moffitt, Caspi, Harrington, & Milne, 2002 1 11/28/2011 Childhood-Onset Conduct Disorder Cleckley’s Psychopath Cleckley, H. (1976). The Mask of Sanity, 5th Edition Superficial charm Absence of nervousness Untruthfulness and insincerity Lack of remorse or shame Unreliability Inadequately motivated antisocial behavior Pathological egocentricity Incapacity for love Poverty in major affective reactions Dimensions of Psychopathy in Children Callous-Unemotional Narcissism Impulsivity Is unconcerned about the feelings of others Thinks he/she more important than others Acts without thinking Does not feel bad or guilty Brags excessively about accomplishments Is unconcerned about school work Uses or cons others Does not plan ahead I. Construct Development Does not keep promises Can be charming in ways that seem insincere Engages in risky activities Blames others for mistakes Gets bored easily Does not show emotions Does not keep same friends Becomes angry when corrected Source: Frick, Bodin, & Barry, 2000 2 11/28/2011 Callous-Unemotional Traits Callous-Unemotional Traits Is unconcerned about the feelings of others. Does not feel bad or guilty. Is unconcerned about school work. Does not show emotions. Does not keep promises. Does not keep the same friends. Is unconcerned about the feelings of others. Does not feel bad or guilty. Is unconcerned about school work. Does not show emotions. Does not keep promises. Does not keep the same friends. Source: Frick, Bodin, and Barry, 2000 Factor Analysis of Inventory of CallousUnemotional Traits Essau et al. 2006; Fanti et al., 2009; Kimonis et al., 2008; Roose et al, 2010 Source: Frick, Bodin, and Barry, 2000 Factor Analysis of Inventory of CallousUnemotional Traits Essau et al., 2006; Fanti et al., 2009; Kimonis et al., 2008; Roose et al., 2010 Callousness I do not care who I hurt to get what I want I am concerned about the feelings of others (I) I do not care if I get into trouble I do not feel remorseful when I do something wrong I do not care about doing things well The feelings of others are unimportant to me Uncaring I do not care about being on time I always try my best (I) I do not like to put the time into doing things well What I think is “right” and “wrong” is different from what other people think I do not let my feelings control me I seem very cold and uncaring to others I work hard on everything I do (I) I apologize (“say I’m sorry”) to persons I hurt (I) I care about how well I do school work (I) I try not to hurt others’ feelings (I) I do things to make others feel good (I) I easily admit to being wrong (I) I feel bad or guilty when I do something wrong (I) 3 11/28/2011 Factor Analysis of Inventory of CallousUnemotional Traits Essau et al., 2006; Fanti et al., 2009; Kimonis et al., 2008; Roose et al., 2010 Unemotional I express my feelings openly (I) Stability of Callous-Unemotional Traits in Children and Adolescents Age 11 to 15 (parent report): ICC =.71 Frick et al. (2003) Age 8 to 17 (parent report): r=.50 Obradovic et al. (2007) I am very expressive and emotional (I) Age 17-24 (self report): r=.60 Blonigen et al. (2006) I do not show my emotions Age 12-24 (self report to PCL-R): r=31 I hide my feelings from others It is easy for others to tell how I am feelings (I) Lynam et al, 2007 21% in upper 10% on CU were elevated as adults 3.22 times the risk of those not in upper 10% Adolescent Sex Offenders Lawing, Frick, & Cruise, 2010 150 adolescent boys detained for a sexual offense II. Association with Severity of Antisocial Behavior Age range 12 - 20 (Mean = 15.89, SD=1.53) 49% African-American Sexual battery (32%) and aggravated rape (15%) were most common charges 86% had history of at least one violent offense 4 11/28/2011 J-SOAP-II Items J-SOAP-II Items Prentky & Righthand, 2003 Prentky & Righthand, 2003 Number of sexual abuse victims Score of 0 = Only 1 known victim Duration of sex offense history Score of 0= Only 1 known sexual offense and no other history of sexual aggression Score of 1 = 2 known victims Score of 2 = 3 or more known victims Score of 1 = There are multiple sex offenses within a brief time period (6 months or less). Score of 2 = There are multiple sex offenses that extend over a period greater than 6 months and involve 1 or more victims. Lawing, Frick, & Cruise, 2010 (n=69) High CU F (df) Sexualized aggression Score of 0 = No gratuitous or expressive aggression. No evidence that the individual intentionally physically hurt the victim or demeaned or humiliated the victim. Partial Score of 2 = Moderate or detailed planning. There must be a clear modus operandi. The offenses may appear “scripted,” with a particular victim and crime location targeted. Score of 1 = Mild amount of expressive aggression. As evidenced by swearing or cursing at the victim, threatening the victim, squeezing, slapping, or pushing the victim. Score of 2 = Moderate to high amount of expressive aggression. As evidenced by punching, kicking, cutting, burning, or stabbing the victim; causing physical injuries that require medical attention. Frick, Cornell, Barry, Bodin, & Dane, 2003 Eta2 (n=81) Score of 1 = Mild degree of planning. Some clear evidence that the individual thought about or fantasized about the sexual offense before the encounter. CU Traits and the Prediction of Antisocial Behavior Adolescent Sex Offenders Low CU Degree of planning in sexual offenses Score of 0 = No planning. All known sexual offenses appear to have been impulsive, opportunistic, sudden, and without any apparent forethought prior to the encounter. CU Traits ________________________________________________________________________________________________ Low Number of Victims .40(.65) .69(.80) 5.65(1, 147)* .037 Offense History .76(.81) .96(.87) 1.98(1, 147) Degree of Planning .44(.58) .67(.69) 4.67(1, 147)* .031 Sexualized Aggression .22(.53) .42(.60) 4.74(1, 147)* .031 Duration of Sexual .013 ______________________________________________________________ Note. *p <.05; Effects are the between group effects from a one-way ANOVA, covarying history of antisocial behavior. Means reported are least squares means adjusted for the covariate. Low Conduct Problems High N=224 SEI =53.49 (12.38) Boys = 32% Caucasian = 92% N=66 SEI = 54.53(19.95) Boys = 52% Caucasian = 91% High Low N=77 SEI=22.46 (22.46) Boys = 60% Caucasian = 64% N=128 SEI = 37.17 (19.10) Boys = 64% Caucasian = 68% 5 11/28/2011 CU Traits and Type of Aggression in a NonReferred Sample CU Traits, Conduct Problems, and Type of Aggression in a Non-Referred Sample Frick, Cornell, Barry, Bodin, & Dane, 2003 Frick, Cornell, Barry, Bodin, & Dane, 2003 1 Mean Age = 12.35 (1.72) 0.8 Gender = 52% Girls / 48% Boys 0.4 0.6 0.2 0 Ethnicity =21% African- American / 79% Caucasian ‐0.2 ‐0.4 ‐0.6 ‐0.8 Mean K-BIT Composite = 104.74 (12.98) Control CU‐only CP‐only CU+CP Reactive Aggression CP: F(1,86)= 37.79; p < .001 Conduct Problem Trajectories Control CU‐only CP‐only CU+CP Proactive Aggression CP: F(1,86)= 22.20; p < .001 CU X CP: F (1,86) = 5.53, p < .05 Self-reported Delinquency Trajectories 3.5 7 6 3 5 2.5 Control CU-Only CP-Only CU+CP Conduct 4 Problems 3 2 1 Number of 2 Self-Reported Total 1.5 Delinquent 1 Offenses Control CU-Only CP-Only CU+CP 0.5 0 Time 1 Time 2 Time 3 Time 4 Frick, Stickle, Dandreaux, Farrell, & Kimonis, 2005 0 Time 1 Time 2 Time 3 Time 4 Frick, Stickle, Dandreaux, Farell, & Kimonis, 2005 6 11/28/2011 Property Delinquency Trajectories 0.7 0.6 0.5 Number of 0.4 Self-Reported Property 0.3 Offenses 0.2 Control CU-Only CP-Only CU+CP 0.1 0 Time 1 Time 2 Time 3 Violent Delinquency Trajectories 1 0.9 0.8 0.7 Number 0.6 of 0.5 Self-Reported 0.4 Violent 0.3 Offenses 0.2 0.1 0 Control CU-Only CP-Only CU+CP Time 1 Time 4 Time 2 Time 3 Time 4 Frick, Stickle, Dandreaux, Farrell, & Kimonis, 2005 Frick, Stickle, Dandreaux, Farrell, & Kimonis, 2005 Cumulative Hazard Curves for Parent-Reported Police Contacts Other Evidence for CU Traits being Associated with Severity of Antisocial Behavior in Youth Frick & Dickens (2006) Review 35 30 10 published concurrent studies 25 Cumulative Rate of Police Contacts Control CU-Only CP-Only CU+CP 20 15 10 5 0 Time 1 Time 2 Time 3 Time 4 Frick, Stickle, Dandreaux, Farrell, & Kimonis, 2005 •As young as age 3 and 4 (Kimonis et al., 2006) 13 published predictive studies •Gretton et al. (2004) - CU traits in adjudicated adolescents (ages 12-18) predicted more violent offenses and shorter time to violent reoffending over 10 year follow-up 5 published studies as negative treatment indicator •Hawes & Dadds (2005) - predicted poor response to parenting intervention in 4 to 8 year old clinic-referred children 7 11/28/2011 CU Traits and the Diagnosis of Conduct Disorder in a Nationally Representative Sample Rowe, Maughan, Moran, Ford, Briskman, & Goodman, 2010 N=5,326 (British Child and Adolescent Mental Health Survey) Ages 5-16 2% of sample had CD 46% of those with CD were high on CU traits CU Traits and the Diagnosis of Conduct Disorder in a Nationally Representative Sample Rowe, Maughan, Moran, Ford, Briskman, & Goodman, 2010 3 year outcome No CD / CU CU only (n=4972) (n=124) CD only (n=38) CD + CU (n=36) Any Disorder 7.7% 33.7% 40.9% 74.8% Conduct Disorder 1.2% 12.3% 13.9% 68.6% Police Contact 6.2% 12.5% 36.4% 57.0% Note: The percentages in bold resulted in significantly different odds ratio when comparing CD‐Only to CD+CU, adjusting for age and gender. Predictive Utility CONTROLLING for Other Indices of Severity McMahon et al., 2010 Predictor (Grade 7) Adult Arrests (n=754) ASPD Symptom Count (n=511) CU Traits .87 ** .46 * CD Sx/Dx .43 ** .19 ODD Sx/Dx ADHD Sx / Dx Childhood onset APSD Diagnosis (n=503) .30 * -.02 -.17 .19 .20 .00 -.04 .01 .58 * .33 * -.11 III. Distinct Developmental Pathways within ChildhoodOnset Conduct Disorder Standardized regression coefficients showing independent contribution. * p < .05; ** p < .01; Adult = 2 years post-high school. For continuous outcomes (adult arrests and ASPD criterion count), the criterion counts of CD, ODD, and ADHD were included as covariates. For the binary outcome (ASPD diagnosis), CD, ODD, and ADHD diagnoses were included as covariates. 8 11/28/2011 Estimates of Genetic Influences on Conduct Problems with and without CU Traits in 7374 7-year old Twins Examples of Emotional Pictures Viding, Blair, Moffitt, & Plomin, 2005 100 90 80 70 60 50 40 30 20 10 0 Non-Shared Environment Shared Environment Genetics Conduct Problems Only Conduct Problems + CU N=210 N=234 9 11/28/2011 Emotional Processing and CU Traits in a Sample of Community Children Kimonis, Frick, Fazekas, & Loney, 2006 50 children (ages 6 -13) of college students Mean age = 9.30 (sd=2.00) Mean SEI = 54.73 (sd = 23.24) 70% Caucasian 24% had received mental health services Emotional Processing and CU Traits in a Sample of Community Children (n=50) Emotional Processing and CU Traits in a Sample of Detained Boys (n=88) Kimonis, Frick, Fazekas, & Loney, 2006 Kimonis, Frick, Munoz, & Aucoin, 2008 25 20 15 Emotional 10 Facilitation 5 To 0 Distress Pictures -5 Std Beta = .27, p = n.s. -10 -15 -20 250 Std Beta = -.46, p < .05 Emotional 200 Facilitation 150 To Distress 100 Pictures Std Beta = .13, p = n.s. 50 0 Low CU Low Aggression Mod CU High Aggression Hi CU Std Beta = -.22, p = n.s. Low CU Low Aggression Mod CU Hi CU High Aggression 10 11/28/2011 Emotional Processing and CU Traits in a Sample of Detained Boys Kimonis, Frick, Munoz, & Aucoin, 2008 Munoz et al., 2008 Task goal - press space bar faster than opponent Win - 50 points + take 0-100 points from opponent + record taunt Lose - Low Provocation (n=8) – Lost 0 to 20 points – Mild taunt, “Nice try! I’ll cut you a break. I’ll only take 10 points this time”. Lose - High Provocation (n=8) – Lose 80 to 100 points – Severe taunt, “You’re so slow my Grandma could beat you. That’s going to cost you 100 points”. 88 adolescent detained boys (13 - 18) Mean age = 15.57 (sd=1.28) Mean PPVT-III = 85.60 (sd = 13.50) •PPVT < 65 excluded 68% African-American Skin Conductance Response after high and low provocation messages (mn amplitude 1 to 5 secs post stimulus). CU Traits and Response to Provocation Published Research Support Frick & White, 2008 Munoz et al., 2008 Mn SCR/ Low Prov Total ICU Competitive Reaction Time Task ‐.25 * Mn SCR/ HI Prov ‐.25 * 31 studies showing different correlates than antisocial behavior or showing it designate a distinct group of antisocial/delinquent youth •Reduced responsiveness to emotional stimuli (n=10) •Abnormal responses to punishment cues (n=10) •Negative correlations with anxiety/neuroticism controlling for level of conduct problems (n=7) 11 11/28/2011 Developmental Model Involving Callous-Unemotional Traits Temperament and Parenting Interactions in Predicting Conscience Development in Pre-Schoolers Cornell & Frick, 2007 Inhibited (N =43) ParentRated Guilt 95 93 91 89 87 85 83 81 79 77 75 Uninhibited (N=44) Std Beta = .13, p = n.s. Std Beta = -.32, p < .05 Low Medium High Inconsistent Discipline Temperament and Parenting Interactions in Predicting Conscience Development in Pre-Schoolers Developmental Model Involving Callous-Unemotional Traits Cornell & Frick, 2007 Inhibited (N =43) ParentRated Guilt 95 93 91 89 87 85 83 81 79 77 75 Uninhibited (N=44) Std Beta = -.08, p = n.s. Std Beta = .38, p < .01 Low Medium High Authoritarian Parenting 12 11/28/2011 Psychopathy Variants Psychopathy Variants Kimonis, Frick, Cauffman, Goldweber, & Skeem, in press Kimonis, Frick, Cauffman, Goldweber, & Skeem, in press Primary Variant (n=122) AnxiousDepressed Anger Maltreatment Secondary Variant (n=43) Non-CU Comparison (n=208) Effect Size (d) 5.43 (4.08) 8.57 (3.66) 5.89 (4.64) .69 92.15 (14.610 101.41 (16.73) 85.10 (16.15) .54 1.56 (1.47) 2.24 (1.46) 1.37 (1.60) .41 Note: Sample was 373 male juvenile offenders housed in a secure confinement facility between the ages of 14 and 17; 53% Hispanic, 29% African-American, 6% Caucasian; 69% were sentenced for violent offense; means with different colors differ significantly using Tukey’s HSD. Characteristics of Antisocial Youth Children without CU traits CU Traits, Conduct Disorder, Intelligence Christian, Frick, Hill, Tyler, & Frazer, 1997 Impulsive, with high rates of ADHD •Adjudicated sample (Caputo et al., 1999) •Clinic-referred sample (Christian et al., 1997) •Community sample (Frick, Bodin, & Barry, 2000) 105 A A 100 Distressed by effects of behavior on others •Adjudicated sample (Pardini et al., 2003) •Clinic-referred sample (Frick et al., 1999) •Community sample (Frick, Cornell, Bodin et al., 2003) Full Scale IQ B 95 90 85 80 High levels of emotional reactivity •Self-report ratings (Pardini et al., 2003) •Emotional words (Loney et al., 2003) •Emotional pictures (Kimonis et al., 2004) 75 70 Clinic Control Impulsive Conduct CU Conduct 13 11/28/2011 CU Traits, Conduct Problems, and Dysfunctional Parenting Wootton, Frick, Shelton, & Silverthorn, 1997 CU Traits, Conduct Problems, and Dysfunctional Parenting Pasalich, Dadds, Hawes, & Brennan, in press 1 Std Beta = -.07, p = n.s. 9 0.8 8 Predicted Number of ODD/CD Symptoms Std Beta = -.14, p = n.s. S 7 6 5 Low CU (n=107) 4 0.6 Conduct Problems 0.4 (Z-score) 0.2 Std Beta = .30, p < .05 Low CU Hi CU High CU (n=48) Std Beta = .47, p < .01 3 0 2 -0.2 1 -0.4 0 ‐5 ‐4 ‐3 ‐2 ‐1 0 1 2 3 4 5 Mother’s Coercive Parenting 6 Note: Participants were 96 clinic-referred boys with conduct disorder (4-12 years) Scores on the Dysfunctional Parenting Composite CU Traits, Conduct Problems, and Dysfunctional Parenting Developmental Model Involving Poor Impulse Control Pasalich, Dadds, Hawes, & Brennan, in press 2 1.5 Std Beta = -.56, p < .05. 1 Conduct Problems (Z-score) 0.5 Std Beta = -.13, p = n.s. Low CU Hi CU 0 -0.5 -1 Mother’s Warmth Note: Participants were 96 clinic-referred boys with conduct disorder (4-12 years) 14 11/28/2011 Summary of Conduct Disorder Pathways Summary of Conduct Disorder Pathways Frick & Dickens, 2006 Frick & Dickens, 2006 Conduct Disorder Childhood‐Onset Subtype Conduct Disorder Adolescent‐Onset Subtype Childhood‐Onset Subtype Primarily Impulsive Type Proposed Specifier for Conduct Disorder for the DSM-V: “With Significant CallousUnemotional Traits” (WWW.DSM5.ORG) 1. Meets full criteria for Conduct Disorder. 2. Shows 2 or more of the following characteristics persistently over at least 12 months and in more than one relationship or setting. The clinician should consider multiple sources of information to determine the presence of these traits, such as whether the person self-reports them as being characteristic of him or herself and if they are reported by others (e.g., parents, other family members, teachers, peers) who have known the person for significant periods of time. Adolescent‐Onset Subtype Callous‐Unemotional Type Proposed Specifier for Conduct Disorder for the DSM-V: “With Significant Callous-Unemotional Traits” Lack of Remorse or Guilt: Does not feel bad or guilty when he/she does something wrong (except if expressing remorse when caught and/or facing punishment Callous-Lack of Empathy: Disregards and is unconcerned about the feelings of others. Unconcerned about Performance: Does not show concern about poor/problematic performance at school, work, or in other important activities. Shallow or Deficient Affect: Does not express feelings or show emotions to others, except in ways that seem shallow or superficial (e.g., emotions are not consistent with actions; can turn emotions “on” or “off” quickly) or when they are used for gain (e.g., to manipulate or intimidate others). 15 11/28/2011 ICD -11: Emotional-interpersonal deficit syndrome (Psychopathy) The key features of emotional-interpersonal deficit syndrome are: lack of sensitivity to the feelings of others and a lack of concern for others’ distress. In addition, there is often a failure to show the person’s own feelings or emotions in most circumstances, lack of remorse, shame or guilt over their own behaviour (unless prompted by being apprehended); marked egocentricity, limited capacity for loving relationships and a relative indifference to the probability of punishment for his or her actions. These features are usually evident from middle childhood and often (but not invariably) persist into adult life. 16 11/28/2011 Evaluation of Functional Family Therapy for Adolescents with CU Traits White, Frick, Lawing, & Bauer, 2010 134 arrested adolescents referred to CMH for FFT Ages 11 - 17 (Mn= 15.34; SD= 1.34) 72% male / 59% African-American Offense type: 45% status 22% violent 19% property 6% drug 17 11/28/2011 Evaluation of Functional Family Therapy for Adolescents with CU Traits Evaluation of Functional Family Therapy for Adolescents with CU Traits White, Frick, Lawing, & Bauer, 2010 Emotional Symptoms Relations w Parents Interpersonal Aggression Relations White, Frick, Lawing, & Bauer, 2010 Conduct Problems Emotional Symptoms Pre‐Tx .41 *** ‐.41 ** ‐.34 ** .62 ** .64 ** Pre‐Tx Post‐TX .23 * ‐.38 ** ‐.31 ** .45 ** .36 ** Post‐TX TX Change TX Change Post‐TX ‐.24 * (‐.09) ‐.02 (‐17) ‐.40 ** (.15) ‐.27 ** (.02) Youth – COM Parent – COM .07 (‐.16) Therapist COM Sessions Attended Treatment Drop‐Out ‐.21 * ‐.28 ** ‐.16 ‐.08 .13 Relations w Parents Interpersonal Aggression Relations Parent – COM Therapist COM ‐.24 * Youth – COM Post‐TX Conduct Problems ‐.40 ** ‐.27 ** Sessions Attended Treatment Drop‐Out ‐.08 .13 Correlations are with CU Traits; treatment change measured by subtracting post‐ treatment scores from pre‐treatment scores; correlations in parenthesis are partial correlations controlling for pre‐treatment scores; COM=Client Outcome Measure; * p <.05 ; ** p < .01 Correlations are with CU Traits; treatment change measured by subtracting post‐ treatment scores from pre‐treatment scores; correlations in parenthesis are partial correlations controlling for pre‐treatment scores; COM=Client Outcome Measure; * p <.05 ; ** p < .01 Evaluation of Functional Family Therapy for Adolescents with CU Traits Evaluation of Functional Family Therapy for Adolescents with CU Traits White, Frick, Lawing, & Bauer, 2010 Emotional Symptoms White, Frick, Lawing, & Bauer, 2010 Relations w Parents Interpersonal Aggression Relations Conduct Problems Pre‐Tx .41 *** ‐.41 ** ‐.34 ** .62 ** .64 ** Post‐TX .23 * ‐.38 ** ‐.31 ** .45 ** .36 ** Youth – COM Parent – COM Therapist COM ‐.21 * ‐.28 ** ‐.16 TX Change Post‐TX Sessions Attended Treatment Drop‐Out Correlations are with CU Traits; treatment change measured by subtracting post‐ treatment scores from pre‐treatment scores; correlations in parenthesis are partial correlations controlling for pre‐treatment scores; COM=Client Outcome Measure; * p <.05 ; ** p < .01 Base Rate Priors CP CU DURING TREATMENT All charges 48% 1.238 ** .995 1.029 Violent charges 15% 1.221 ** .949 * 1.165 ** 6 MONTH POST All charges 42% 1.100 * 1.004 1.035 Violent charges 14% 1.118 * .997 1.082a 12 MONTH POST All charges 63% 1.072 Violent charges 22% 1.134 * 1.005 1.013 .998 1.032 Coefficients are odds ratios from logistic regression analyses; a p = .057; * p < .05; *** P < .01 18
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