Careful review of the following scientifically verifiable information will establish the fact that, unless several issues are adequately addressed, precision (personalized) medicine cannot become a reality. For example, signaling molecules in the body that regulate cellular activity have minerals and elements as their primary constituents. When this fact is recognized, principles of physical science can be applied in order to assess interactions and imbalances that can disrupt cellular health and well-being. In simple terms, “sick” cells will create “sick” tissues and “sick” tissues will create the “sick” glands and organs that result in chronic diseases. An example of minerals and elements that interact and can disrupt cellular health and well-being is: http://www.mcfip.net/upload/Basic%20Data%20not%20Big%20Data.pd f Cellular abnormalities can be a primary factor for the causes of chronic diseases. An example is: http://www.mcfip.net/upload/Community%20Acquired%20Pneumonia %20-%20Hospital%20Readmissions.pdf Current methods to identify causes of chronic diseases for use as a foundation from which precision (personalized) medicine can be developed are using a flawed genomic model that requires algorithmic calculations to assess 3 billion base pairs to determine abnormalities. http://www.mcfip.net/upload/Basic%20Data%20not%20Big%20Data.pd f While current genomic testing methods will allow for DNA comparisons, the outcomes (reports) will identify aberrations but the conversion of these findings into practical applications that will prevent 1 or treat chronic diseases will be nearly impossible to convert into medical treatment protocols. http://www.mcfip.net/upload/Big%20Data%20Efforts%20Are%20Flaw ed.pdf Chronic diseases are the result of imbalances that occur between intraand intercellular communication. Examples of such interactions include the following: http://www.mcfip.net/upload/Blood%20Flow%20Imbalances%20(Strok es%20-%20Heart%20Attacks).pdf http://www.mcfip.net/upload/BodilyGasHomeostasis(Overview)9-1115.pdf Summary The many factors associated with obstacles that stand in the way of the evolution of precision (personalized) medicine are too complex to fully explain a document of this nature. With that being said, however, interested parties seeking to pursue these issues should contact The Center for Modeling Optimal Outcomes at [email protected] 2
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