Chapter 12
The
Endomembrane
System and
Peroxisomes
Lectures by
Kathleen Fitzpatrick
Simon Fraser University
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What do the membrane-bound
organelles do?
How are proteins made?
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Figure 12-1
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Rough ER—other functions
• Rough ER is the site for
– The initial steps of addition of carbohydrates to
glycoproteins
– The folding of polypeptides
– Recognition and removal of misfolded proteins
– Assembly of multimeric protein complexes
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Figure 12-3
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Table 12-1
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Which of these is NOT a part of
the endomembrane system?
•
•
•
•
1) Golgi
2) Endosomes
3) Rough endoplasmic reticulum
4) Mitochondria
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Which of these is most likely
involved in the inactivation of
birth-control medications by St.
John’s wort?
•
•
•
•
1) Golgi
2) Endosomes
3) Rough endoplasmic reticulum
4) Smooth endoplasmic reticulum
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What does the Golgi apparatus do
for proteins?
How does it do that?
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Figure 12-4A
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Figure 12-4B
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Figure 12-6
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How are proteins glycosylated?
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Figure 12-7
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How are proteins sent to the right
destination? How do they stay there?
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Figure 12-8
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Figure 12-9
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How do exocytosis and endocytosis
work?
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Figure 12-12A
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Figure 12-13
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How are vesicles formed?
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Figure 12-15
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Figure 12-16
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Figure 12-17A
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Figure 12-17B, C
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Figure 12-18A, C
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Figure 12-18B, D
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How do vesicles attach to and fuse
with a target membrane?
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Figure 12-19
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