Student Name: _____________________________ Date: ____________________ What does DNA do? Activity 1 - Base Pairs ___ 1) Get a base pair. What is the name on the back? Look at its shape. Walk around the room and find someone that you can match up with to make a rectangle. ___ 2) Look at how people matched up. What rule can you come up with for the base pairs? Write this rule down. Rule: Background: DNA is a cells code for creating proteins, which are the building blocks of life. In order for the code to be turned into proteins, the cell must go through some processes. The activities below will teach you about these processes. One rule to remember: the base pairs for DNA are Thymine (T), Adenine (A), Guanine (G), and Cytosine (C). For RNA, Uracil (U) replaces Thymine. -1– Student Name: _____________________________ Date: ____________________ Activity 2 - Replication ___ 1) With a partner, get a strand of DNA from your teacher. ___ 2) Unzip the strand, with scissors. Give one strand to your partner and keep the other one. ___ 3) Follow the base pair rule to fill in the missing base pairs for your strand. ___ 4) Compare your new DNA strand with your partners. Are they similar? What have you done? Where did this process take place in the cell? Why is this process important? Activity 3 -Transcription and Translation ___ 1) Use the amino acid chart to write out a code that spells a word that is between 8-10 letters long. T here are no letters B, J, O, U, X, or Z! Word **Remember, RNA uses Uracil instead of Thymine** mRNA Strand DNA Strand (Base Pairs) ___ 2) Exchange your code with someone else in the class. -2– Student Name: _____________________________ Date: ____________________ ___ 3) Write down the code you received below: DNA Strand: ___ 4) Take the code you have been given and transcribe it into an mRNA strand. Record your code below: **Remember, RNA uses Uracil instead of Thymine** mRNA Strand: ___ 5) Where in the cell are you located now? ___ 6) Take your mRNA strand and translate it by matching it up with the correct amino acid. Record this below and write the letter for the each amino acid. Where does this take place. Amino Acid Code: Location of Translation -3– Student Name: _____________________________ Date: ____________________ ___ 6) What does this word represent in the cell? ___ 7) Check with the person to see if your mRNA strand and word were correct or not. ___ 8) Did you make a mistake with the code? Did it affect the spelling of the word? What do we call it when a cell makes a mistake like this? -4– Student Name: _____________________________ Date: ____________________ Amino Acid Chart Lyl4Science -5–
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