Weber State University Radiologic Technology 4603 MRI Physics and Instrumentation _____________________________________________ Instructor: Rex T. Christensen MHA R.T. (R) (MR) (CT) Water Molecule H O 2 • Atom + Atom = molecule • A water molecule consists of 2 hydrogen atoms and 1 oxygen atom. 1 Water Molecule H O 2 • Hydrogen in the body is found predominately in three forms: 1. Free water in body fluids (CSF) 2. Water bound to large molecules (proteins) 3. Hydrogen atoms within fat. Hydrogen Atom •Has the simplest atomic structure. •Contains one proton and one electron. •The nucleus of a hydrogen atom contains only a proton. •Therefore, hydrogen atoms are often referred as “protons” •Abundant in the body. 2 MR Active Nuclei • Nuclei that aligns its axis to a magnetic field. • They do this because of electromagnetic induction: • Angular momentum or spin. • Posses an electrical charge (+) • If two of these characteristics are present it induces the third - magnetism • Called a magnetic moment MR Active Nuclei: Naturally occurring nuclei with an odd number of Protons or Neutrons. Gyromagnetic ratio is a constant for each type of MR active nuclei. 3 Precession Precession is the wobble of a top Precessional Frequency is the speed it wobbles. (Mhz) Larmor Frequency: The Larmor frequency is also called the Precessional frequency. Precession is a “wobble” of the hydrogen atom. 4 Larmor Equation: MEMORIZE THIS! 5 Larmor Equation: So What? It calculates the operating frequency of the MRI magnet. 42.57 Mhz @ 1 Tesla What would it be at 1.5T? 3.0T? 1.5T = 63.9 Mhz 3.0T = 127.7 Mhz What is a Vector? A quantity (magnitude) that has direction. http://www.e-mri.org/nmr/excitation-nmr.html 6 Cartesian Coordinates Frames of reference: Stationary Frame: Looking at a moving object from a stationary position. Rotating Frame: Looking at a moving object while on the moving object. 7 Hydrogen Atoms before being placed in the MRI: Hydrogen Atoms after being placed in the MRI: 8 Parallel vs. Anti-parallel: Anti-parallel Parallel Anti-parallel = High energy states. Parallel = Low energy states. Net Magnetization: 9 Hydrogen and Field Strength • As field strength increases the number of Hydrogen atoms becomes more visible. 10 Longitudinal and Transverse Magnetization Longitudinal Magnetization is also known as: • T1 Relaxation • Spin-lattice Relaxation Transverse Magnetization is also known as: • T2 Relaxation • Spin-spin Relaxation Resonance: When an RF pulse is turned on and its frequency matches that of the frequency of the hydrogen atom energy is transferred. This tips the hydrogen atoms down into the transverse plane (90 degrees). The magnitude of the flip angle (i.e. 90 degrees) depends upon the amplitude and duration of the RF pulse. 11 Hard/Soft RF Pulses: Hard Pulse: Strong, very short RF pulse. Soft Pulse: Weaker, longer RF pulse. The duration of the pulse rarely exceeds 10 ms. T1 Relaxation: 12 T1 Relaxation: T2 Relaxation: This relaxation is also called: •Dephasing •Incoherence •Lack of phase coherence •T2 Decay Coherence: means sticking together. 13 T2 Relaxation: Free Induction Decay (FID): 14 Free Induction Decay (FID): The induction in reduced signal is called Free Induction Decay (FID) Coils 15 Coils Relaxation Times: T1 Relaxation Time: 63 % relaxation of the tissue along the longitudinal (z) axis. T2 Relaxation Time: 63% decay of the tissue along the transverse (xy) axis. 16 TR = Time to Repetition Time (ms) between the beginning of one pulse sequence and the beginning of the succeeding pulse sequence. TE = Time to Echo Time (ms) between the center of the 90-degree pulse and the center of the spine echo. 17 Image Contrast: T1 contrast = short TR and short TE. T2 contrast = long TR and long TE. PD contrast = long TR and short TE. 18
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