Europaisches P a t e n t a m t
(19)
European Patent Office
© Publication number:
Office europeen des brevets
EUROPEAN
©
PATENT A P P L I C A T I O N
© int. CI.4: C 07 F 9 / 6 5
A 61 K 3 1 / 6 6
© Date of filing: 16.04.86
© Priority: 25.04.85 CS 3017/85
© Applicant: Ceskoslovenskaakademieved
Narodni3
PrahaKCS)
© Date of publication of application:
30.12.86 Bulletin 86/52
Date of deferred publication of search report: 20.05.87
© Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
© Inventor: Holy,Antonin
No1699Trebesovska
1 Horni Pocernice(CS)
j© Inventor: Rosenberg, Ivan
No 82/852 Obrancu miru
Praha7(CS)
j
!
!© Representative: MATTHEWS HADDAN &CO
Haddan House 33 Elmfield Road
Bromley, Kent BR1 1SU(GB)
© 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use.
© The invention relates to SMphosphonylmethoxyalkyl)adenines of the general formula I
s
i
B1CH(R2)-OCH2P-OH
OH
0>
ID
<t
tO
o
CM
206
A3
© Application number: 86302822.1
CO
<
0
wherein R1 is a hydrogen atom, an alkyl group containing one
to three carbon atoms, or a hydroxymethyl group, R2 is a
methylene, ethylene, propylene, ethylidene, methbenzyloxyethylene,
tetrahydropyran-2oxyethylene,
1,2-0(l-ethoxyethoxy)ethylene
or
yloxyethylene,
isopropylidene-1,2-dihydroxypropylene group the method of
their preparation and utilization.
Compounds of the general formula I exhibit biological
effects (e.g. antiviral) or can be converted into compounds
with such effects.
Q.
LU
Croydon Printing Company Ltd
459
J
)
Qtjf
European Patent
£
_
EUROPEAN SEARCH REPORT
EP
Category
D,Y
Y
DOCUMENTS CONSIDERED TO BE RELEVANT
Citation of document with indication, where appropriate,
of relevant passages
Relevant
to claim
F R - A - 2 539 132
( CESKOSLOVENSKA
AKADEMIE VED. )
* Whole d o c u m e n t *
1,2
E P - A - 0 049 072
(ENS
INC. )
* Whole d o c u m e n t *
1,2
BIOLOGICALS
86
0 2 0 6 4 5 9
30 2 8 2 2
CLASSIFICATION OF THE
APPLICATION (Int CI ")
C 07
A 61
F
K
9/65
31/66
TECHNICAL FIELDS
SEARCHED (Int CU)
C 07
F
9/00
The present search report has been drawn up for all claims
Place of search
THE HAGUE
Date of completion of the search
13-02-1987
CATEGORY OF CITED DOCUMENTS
X : particularly relevant if taken alone
Y : particularly relevant if combined with another
document of the same category
A : technological background
O : non-written disclosure
P : intermediate document
Examiner
BESLIER L . M .
T : theory or principle underlying the invention
E : earlier patent document, but published on, or
after the filing date
D : document cited in the application
L : document cited for other reasons
& : member of the same patent family, corresponding
document