DRUGS TO BE AVOIDED BY CONGENITAL LONG QT PATIENTS
CredibleMeds® has reviewed all available evidence and has placed the following drugs in
designated risk categories for their risk of causing torsades de pointes (TdP): Known Risk
of TdP (KR), Possible Risk of TdP (PR), Conditional Risk of TdP (CR) or Special Risk
(SR). The full description of these categories can be found on the CredibleMeds website.
We recommend that patients with Congenital Long QT Syndrome avoid use of these
medicines if at all possible or take them under close medical observation.
Generic Name
Brand Name
Generic Name
Brand Name
Generic Name
Brand Name
Bepridil (KR)
Vascor
Delamanid (PR)
Deltyba
Bortezomib (PR)
Velcade and others
Desipramine (PR)
Pertofrane and others
Bosutinib (PR)
Bosulif
Precedex and others
Buprenorphine (PR)
Butrans and others
Dexmedetomidine
(PR)
Capecitabine (PR)
Xeloda
Dexmethylphenidate
(SR)
Focalin and others
Ceritinib (PR)
Zykadia
Elavil (Discontinued
6/13) and others
Dextroamphetamine
(Dexamfetamine) (SR)
Dexedrine and others
Chloral hydrate (CR)
Aquachloral and
others
Amphetamine
(Amfetamine) (SR)
Adderal-XR and others
Chloroquine (KR)
Aralen
Diphenhydramine
(CR)
Benadryl and others
Amphotericin B (CR)
Fungilin and others
Chlorpromazine (KR)
Thorazine and others
Disopyramide (KR)
Norpace
Anagrelide (KR)
Agrylin and others
Cilostazol (KR)
Pletal
Dobutamine (SR)
Dobutrex
Apomorphine (PR)
Apokyn and others
Ciprofloxacin (KR)
Cipro and others
Dofetilide (KR)
Tikosyn
Arformoterol (SR)
Brovana
Cisapride (KR)
Propulsid
Dolasetron (PR)
Anzemet
Aripiprazole (PR)
Abilify and others
Citalopram (KR)
Celexa and others
Domperidone (KR)
Motilium and others
Arsenic trioxide (KR)
Trisenox
Clarithromycin (KR)
Biaxin and others
Donepezil (KR)
Aricept
Artenimol+piperaquine
(PR)
Clomipramine (PR)
Anafranil
Dopamine (SR)
Intropine
Eurartesim
Clozapine (PR)
Clozaril and others
Doxepin (CR)
Sinequan and others
Asenapine (PR)
Saphris and others
Cocaine (KR)
Cocaine
Dronedarone (KR)
Multaq
Astemizole (KR)
Hismanal
Crizotinib (PR)
Xalkori
Droperidol (KR)
Inapsine and others
Atazanavir (CR)
Reyataz and others
Cyamemazine
(cyamepromazine)
(PR)
Droxidopa (SR)
Northera
Tercian
Efavirenz (PR)
Sustiva and others
Dabrafenib (PR)
Tafinlar
Ephedrine (SR)
Rynatuss and others
Dasatinib (PR)
Sprycel
Epinephrine
(adrenaline) (SR)
Primatene and others
Degarelix (PR)
Firmagon
Eribulin mesylate (PR)
Halaven
Erythromycin (KR)
E.E.S. and others
Albuterol (salbutamol)
(SR)
Proventil and others
Alfuzosin (PR)
Uroxatral
Amantadine (CR)
Symmetrel and others
Amiodarone (KR)
Cordarone and others
Amisulpride (CR)
Solian and others
Amitriptyline (CR)
Atomoxetine (PR)
Strattera
Azithromycin (KR)
Zithromax and others
Bedaquiline (PR)
Sirturo
Bendamustine (PR)
Treanda and others
Bendroflumethiazide or
bendrofluazide (CR)
Aprinox
If list is printed, check website at www.crediblemeds.org • Please see Disclaimer below • List continued over
Generic Name
Brand Name
Generic Name
Brand Name
Generic Name
Brand Name
Escitalopram (KR)
Cipralex and others
Ibogaine (KR)
None
Metaprel and others
Esomeprazole (CR)
Nexium and others
Ibutilide (KR)
Corvert
Metaproterenol
(orciprenaline) (SR)
Ezogabine (Retigabine)
(PR)
Iloperidone (PR)
Fanapt and others
Methadone (KR)
Dolophine and others
Potiga and others
Desoxyn and others
Famotidine (PR)
Pepcid and others
Methamphetamine
(Metamfetamine) (SR)
Felbamate (PR)
Felbatol
Methylphenidate (SR)
Ritalin and others
Metoclopramide (CR)
Reglan and others
Fenfluramine (SR)
Imipramine (melipramine)
(PR)
Tofranil
Indacaterol (SR)
Arcapta Neohaler (US) and
others
Indapamide (CR)
Lozol and others
Metronidazole (CR)
Flagyl and many others
Isoproterenol (SR)
Medihaler-Iso and others
Midodrine (SR)
ProAmatine and others
Isradipine (PR)
Dynacirc
Mifepristone (PR)
Korlym and others
Itraconazole (CR)
Sporanox and others
Mirabegron (PR)
Myrbetriq
Ivabradine (CR)
Procoralan and others
Mirtazapine (PR)
Remeron
Ketanserin (PR)
Sufrexal
Moexipril/HCTZ (PR)
Uniretic and others
Ketoconazole (CR)
Nizoral and others
Moxifloxacin (KR)
Avelox and others
Lansoprazole (CR)
Prevacid
Necitumumab (PR)
Portrazza
Pondimin and others
Fingolimod (PR)
Gilenya
Flecainide (KR)
Tambocor and others
Fluconazole (KR)
Diflucan and others
Fluoxetine (CR)
Prozac and others
Flupentixol (PR)
Depixol and others
Fluvoxamine (CR)
Faverin and others
Formoterol (SR)
Foradil and others
Furosemide (frusemide)
(CR)
Lasix and others
Lapatinib (PR)
Tykerb and others
Nelfinavir (CR)
Viracept
Galantamine (CR)
Reminyl and others
Lenvatinib (PR)
Lenvima
Nicardipine (PR)
Cardene
Garenoxacin (CR)
Geninax
Leuprolide (PR)
Lupron and others
Nilotinib (PR)
Tasigna
Gatifloxacin (KR)
Tequin
Norepinephrine (SR)
Levophed
Factive
Levalbuterol (levsalbutamol)
(SR)
Xopenex and others
Gemifloxacin (PR)
Norfloxacin (PR)
Noroxin and others
Granisetron (PR)
Kytril and others
Levofloxacin (KR)
Levaquin and others
Nortriptyline (PR)
Pamelor and others
Levomepromazine (KR)
Nosinan and others
Nusinersen (PR)
Spinraza
Levomethadyl acetate (KR)
Orlaam
Ofloxacin (PR)
Floxin
Levosulpiride (KR)
Lesuride and others
Olanzapine (CR)
Zyprexa and others
Lisdexamfetamine (SR)
Vyvanse
Olodaterol (SR)
Striverdi Respimat
Lithium (PR)
Eskalith and others
Omeprazole (CR)
Losec and others
Loperamide (CR)
Imodium and many other
OTC and Rx brands
Ondansetron (KR)
Zofran and others
Osimertinib (PR)
Tagrisso
Grepafloxacin (KR)
Raxar
Halofantrine (KR)
Halfan
Haldol (US & UK) and
others
Haloperidol (KR)
Hydrochlorothiazide (CR)
Apo-Hydro and others
Hydrocodone - ER (PR)
Hysinglaâ„¢ ER and others
Hydroxychloroquine (CR)
Plaquenil and others
Hydroxyzine (CR)
Atarax and others
Melperone (PR)
Bunil and others
Mesoridazine (KR)
Serentil
If list is printed, check website at www.crediblemeds.org • Please see Disclaimer below • List continued over
Generic Name
Brand Name
Generic Name
Brand Name
Generic Name
Brand Name
Oxaliplatin (KR)
Eloxatin
Quinidine (KR)
Quinaglute and others
Telavancin (PR)
Vibativ
Oxytocin (PR)
Pitocin and others
Quinine sulfate (CR)
Qualaquin
Telithromycin (PR)
Ketek
Paliperidone (PR)
Invega and others
Ranolazine (CR)
Ranexa and others
Terbutaline (SR)
Brethine and others
Panobinostat (PR)
Farydak
Ribociclib (PR)
Kisqali
Terfenadine (KR)
Seldane
Pantoprazole (CR)
Protonix and others
Rilpivirine (PR)
Edurant and others
Terlipressin (KR)
Teripress and others
Risperidone (PR)
Risperdal
Terodiline (KR)
Micturin and others
Ritodrine (SR)
Yutopar
Tetrabenazine (PR)
Nitoman and others
Ritonavir (CR)
Norvir
Thioridazine (KR)
Mellaril and others
Romidepsin (PR)
Istodax
Tiapride (PR)
Tiapridal and others
Roxithromycin (KR)
Rulide and others
Tizanidine (PR)
Zanaflex and others
Salmeterol (SR)
Serevent and others
Tolterodine (PR)
Detrol and others
Saquinavir (PR)
Invirase(combo)
Torasemide (CR)
Demadex and others
Sertindole (PR)
Serdolect and others
Toremifene (PR)
Fareston
Sertraline (CR)
Zoloft and others
Trazodone (CR)
Sevoflurane (KR)
Ultane and others
Desyrel (discontinued 6/13)
and others
Sibutramine (SR)
Meridia
TrimethoprimSulfamethoxazole (SR)
Septra and others
Solifenacin (CR)
Vesicare
Trimipramine (PR)
Surmontil and others
Sorafenib (PR)
Nexavar
Tropisetron (PR)
Navoban and others
Sotalol (KR)
Betapace and others
Vandetanib (KR)
Caprelsa
Sparfloxacin (KR)
Zagam
Vardenafil (PR)
Levitra
Sulpiride (KR)
Dogmatil and others
Vemurafenib (PR)
Zelboraf
Sultopride (KR)
Barnetil and others
Venlafaxine (PR)
Effexor and others
Sunitinib (PR)
Sutent
Tacrolimus (PR)
Prograf and others
Vilanterol/fluticasone furoate
(SR)
Breo Ellipta
Tamoxifen (PR)
Nolvadex(discontinued
6/13) and others
Voriconazole (CR)
VFend
Vorinostat (PR)
Zolinza
Telaprevir (CR)
Incivo and others
Ziprasidone (CR)
Geodon and others
Zotepine (PR)
Losizopilon and others
Papaverine HCl (Intracoronary) (KR)
none
Paroxetine (CR)
Paxil and others
Pasireotide (PR)
Signifor
Pazopanib (PR)
Votrient
Pentamidine (KR)
Pentam
Perflutren lipid
microspheres (PR)
Definity and others
Perphenazine (PR)
Trilafon and others
Phentermine (SR)
Adipex P and others
Phenylephrine (SR)
Neosynephrine
Phenylpropanolamine (SR)
Pilsicainide (PR)
Acutrim and others
Sunrythm
Pimavanserin (PR)
Nuplazid
Pimozide (KR)
Orap
Pipamperone (PR)
Dipiperon (E.U) and others
Posaconazole (CR)
Noxafil and others
Probucol (KR)
Lorelco
Procainamide (KR)
Pronestyl and others
Promethazine (PR)
Phenergan
Propofol (KR)
Diprivan and others
Prothipendyl (PR)
Dominal and others
Pseudoephedrine (SR)
Quetiapine (CR)
PediaCare and others
Seroquel
Note: Medicines on this list are reviewed on an ongoing basis to assure that the available evidence supports their continued placement on this list. The list changes
regularly and we recommend checking the website at crediblemeds.org for the most up-to-date information. There may be many additional brand names that are not listed
on this form.
Disclaimer and Waiver: The information presented is intended solely for the purpose of providing general information about health-related matters. It is not intended for
any other purpose, including but not limited to medical advice and/or treatment, nor is it intended to substitute for the users relationships with their own health care
providers. To that extent, by use of this website and the information it contains, the user affirms the understanding of the purpose and releases AZCERT, Inc. from any
claims arising out of his/her use of the website and its lists. The absence of drugs from these lists should not be considered an indication that they are free of risk of QT
prolongation or torsades de pointes. Many medicines have not been tested for this risk in patients, especially those with congenital long QT syndrome.
Generated: June 18, 2017.
List last revised: May 17, 2017