Anatomy & Physiology Basic Skeletal Structures
Skeletal System 3.2: Bone Cell Structure
ICan2Ed, Inc.
Osteoblasts are cells with a single nucleus
(mononucleate) bone-forming cells that descend
from a form of stem cells that have the capacity to
become osteoblasts and build new bone cells. The
cells that create new bone cells are called
o________.
New bone cells are made by a specialized cell
called an o________.
“Mononucleate” refers to a cell that has only one
nucleus. The mononucleate cell that builds new
bone cells is the o_______.
The osteiod seam is a narrow region of newly
formed organic matrix, not yet mineralized. New
bone cells are laid down in the osteoid seam by
o_______.
O_______ are the immature bone cells, and
eventually become entrapped in the bone matrix to
become osteocytes- the mature bone cell.
1
Young bone cells that have not undergone
calcification are known as o_________.
The cells that create new bone cells are called
o________.
New bone cells are laid down in the osteoid seam
by o_______.
Osteocytes are osteoblasts that have migrated into
and become trapped and surrounded by bone
matrix that they themselves created. Bone matrix
is made when osteoblasts become o________.
Lacunae are spaces in bones. O_______ occupy
the lacunae until they become calcified, creating
new bone matrix.
Osteocytes migrate into the l______, where they
become new b_____ m______.
2
The bone cell responsible for new bone growth is
the o_______.
The bone cell responsible for bone matrix
maintenance is the o_______.
The bone cell responsible for calcium levels in the
body is the o_______.
The cells that create new bone cells are called
o________.
New bone cells are laid down in the osteoid seam
by o_______.
The bone cell responsible for new bone growth is
the o_______.
The bone cell responsible for calcium levels in the
body is the o_______.
3
The bone cell responsible for breaking down old
or damaged bone cells is the o_______.
O_______ are large cells with multiple nuclei,
located on bone surfaces, or resorption pits, called
Howship's lacunae.
The resorption pits, also called Howship’s
lacunae, are all that remains after the o_______
breaks down the bone tissue.
O_______ migrate to discrete bone surfaces. Upon
arrival, active enzymes, such as tartrate resistant
acid phosphatase, are secreted against the mineral
substrate.
The bone cell responsible for releasing calcium
and phosphorus back into the blood stream is the
o________.
The cells that create new bone cells are called
o________.
New bone cells are laid down in the osteoid seam
by o_______.
4
The bone cell responsible for new bone growth is
the o_______.
The bone cell responsible for calcium levels in the
body is the o_______.
The bone cell responsible for breaking down old
or damaged bone cells is the o_______.
The bone cell responsible for releasing calcium
and phosphorus back into the blood stream is the
o________.
Review
The cells that create new bone cells are called
o________.
New bone cells are laid down in the osteoid seam
by o_______.
The bone cell responsible for new bone growth is
the o_______.
The bone cell responsible for calcium levels in the
body is the o_______.
The b____ c____ responsible for breaking down
5
old or damaged bone cells is the o_______.
35
The bone cell responsible for releasing calcium
and phosphorus back into the blood stream is the
o________.
6