2016 ILSI Annual Report Global Partnerships for a Healthier World International Life Sciences Institute Global Partnerships for a Healthier World Science for the Public Good All ILSI activities have a primary public purpose and benefit. Collaboration Scientists from geographically diverse regions of the world can best address complex science and health issues by sharing their unique skills, insights, and perspectives. Shared Values ILSI believes scientists from industry, government, and academia and other sectors of society can and should work together to identify and address topics of common interest. Table of Contents 2From the President 3From the Chair 4Risk Science and Toxicology 6Food Safety 8Nutrition and Health 10Sustainable Agriculture and Nutrition Security 12Regional Cooperation 152016 Board of Trustees 162016 Supporting Companies 202015 Financial Snapshot From the President One of ILSI’s strengths is its ability to pool financial and human resources so we can achieve more with less, and each year I am incredibly impressed with how much our organization accomplishes. 2016 was no different; dedicated staff, member volunteers, and science advisors organized just under 300 scientific meetings and produced 120 scientific publications. I want to draw your attention to a few accomplishments. Peter van Bladeren, PhD ILSI President We launched a new, enhanced and greatly improved website. Good communication of ILSI’s mission and our contributions to the scientific community remains a priority. The website is the central resource for finding information about our scientific outputs, our impact on health and safety, and our operating principles for achieving our mission. The new site is reorganized and streamlined and has an eye-catching new designed that is mobileready; i.e., it is compatible for use on tablets and smart phones which account for an increasing share of devises used by people visiting our site. I am pleased to say we are averaging about 13,000 website visitors each month, which is approaching our goal of 15,000 per month. In addition to communication, collaboration is essential to what ILSI is as an organization and to our success. I am pleased to recognize our branches in Asia for being leaders in crossgeography collaboration. In 2016, ILSI Focal Point in China, ILSI Japan, and ILSI Korea held their 8th BeSeTo (Beijing – Seoul – Toyko) meeting, which now regularly includes ILSI Southeast Asia Region and ILSI Taiwan. I am very excited to say this One ILSI spirit of cooperation is spreading. For the first time, ILSI branches in Latin America organized a joint annual meeting at which they debated their shared vision for the region and prioritized topics on which they will work collectively. I encourage you to read about both examples of ILSI’s commitment to setting and working toward common goals on page 12 of this annual report. There are many other descriptions of our success in 2016 in this report. It is, however, only a snapshot. I encourage you to visit the new ILSI website for a more complete view of our work and impact at www.ilsi.org. 2016 was not without its challenges. Activists continue to criticize scientific partnerships that involve private sector actors and industry-funded science. It is unfair to be sure, but it serves as a reminder for us to remain true to our mission, maintain the highest levels of transparency, and be ready to defend our integrity. Fortunately, 2016 offered more opportunities than it did constraints. The Board of Trustees, staff leadership, and I have enjoyed working on our strategic goals to optimize the structure and function of the organization, particularly the ILSI parent entity. It is difficult but rewarding work to envision what ILSI can be in ten years’ time and beyond, and to develop the framework that will allow us to adapt and flourish in the coming years. I want to thank all of those who contributed to this effort in 2016 and I look forward to sharing a range of recommendations with all of you in 2017. Peter van Bladeren, PhD ILSI President 2 ILSI Annual Report 2016 From the Chair It is an honor to serve as Chair of the ILSI Board of Trustees. I enjoy engaging with fellow trustees, members and sciences advisors at-large, and staff on our common goal to see ILSI thrive. I feel especially privileged to work with colleagues on the Board and staff leadership to envision what ILSI can and should be now and into the future. The effort we put into defining ILSI involved my own coming to understand what ILSI means to me as a scientist. Why do I, and so many others like me, willingly volunteer our time to help ILSI succeed? Yes, of course, I believe in the organization’s mission to improve the human condition through science. It is more than this, however. It is also how we achieve the mission. First there is collaboration. Last year in this space, I wrote ILSI has a challenge: a challenge to be the best, most transparent public-private partnership (PPP) it could be, even in, or perhaps especially in, an environment when PPPs are viewed with suspicion. Many of us who associate with ILSI are criticized for partnering with our scientific counterparts in industry. Our integrity is questioned because of ILSI’s corporate funding. However, this very collaboration, which is done transparently, improves the scientific process. I am involved with ILSI because I can exchange scientific perspectives with people from other academic institutions, industry, and government agencies in a respectful, neutral forum. We may not always agree with each other, but we always listen and learn from each other. Our cooperation leads to better scientific outcomes. understood for science to inform culturally appropriate solutions. Through ILSI’s international network of dedicated scientists and staff, we are more closely connected than we otherwise would be. I am involved with ILSI because I am enriched by the insights experts from throughout the Americas, Asia, Africa, and Europe bring to ILSI’s attention. I see the challenges facing human and environmental health in local and regional context and I recognize opportunities to resolve them in context because of ILSI. Science is translated into solutions. We come to the ILSI table with different interests. Industry wants to make safe, effective products. Governments want to ensure the health and safety of their citizens. Academic researchers want to foster innovation. The sharing of perspectives and experiences that takes place at the ILSI table leads to better decision making. Alan Boobis, OBE Chair International Life Science Institute Board of Trustees I am involved with ILSI because people with different needs still share common interests and concerns. I am rewarded to see science used by people with these diverse needs to develop and implement solutions that help improve human and environmental health and well-being. Serving as Chair of the ILSI Board of Trustees and my many years of previous collaboration with ILSI before that, have been extremely gratifying. I hope all of us, and particularly public-sector scientists, appreciate the role we play in this dynamic, important institution, even when – especially when – our contribution to it is challenged. Alan Boobis, OBE Chair, ILSI Board of Trustees Collaboration is done on an international scale. Issues of science and health do not respect political boundaries. However, local and regional circumstances must be known and www.ilsi.org 3 Risk Science and Toxicology ILSI conducts clinical research and translates science into practical tools that help protect the health of the environment, ensure the safety of our food and water supplies, and demonstrate the safety and efficacy of drugs and consumer products. Quality of Life During and After Cancer Established by HESI in February 2016, the THRIVE Network began a first-ofits-kind seed grant program focused on improving quality of life for cancer patients and survivors. Friends of Cancer Research (Friends) and the National Patient Advocate Foundation (NPAF) joined HESI in the initiative to make quality of life an active research priority for cancer patients and survivors. The HESI, Friends, and NPAF partnership brings together a collective 65 years of organizational experience in improving the lives of cancer patients and survivors through innovative and effective research, outreach, and educational programs. THRIVE brings together patients, clinicians, basic researchers, drug developers, and government scientists to define and reduce immediate and long-term adverse effects from cancer therapy. The THRIVE partners are committed to creating an active forum to enhance understanding of the causes of treatment-related adverse effects both during treatment and in years following, and to enhance the options available to patients to ensure that they can both survive and thrive. 4 ILSI Annual Report 2016 In October 2016, US Vice President Joe Biden released a final report on the Cancer Moonshot Task Force, which names THRIVE as a participant in the Moonshot program to achieve a decade’s worth of progress in preventing, diagnosing, and treating cancer in five years. Using High-Throughput Screening for Chemical Safety in the Food Supply Thousands of chemicals are directly and indirectly added to food to enhance and preserve taste and appearance and to prevent spoilage. Advances in molecular and cellular biology, testing technologies, and computational toxicology have paved the way for animal-free (in vitro), highthroughput screening (HTS) that can characterize chemical interactions with highly specific biological processes rapidly and efficiently. The US Environmental Protection Agency’s ToxCast HTS program, for example, has examined over 3,000 chemicals to assess their bioavailability in vitro. Cooperation on ERA among the ILSI Research Foundation, ILSI Japan, and ILSI Korea started in 2011. Events in 2016 highlight the ability of ILSI organizations to engage in long-term, cooperative programs to help improve ERA policies, procedures, and practice at the local and regional level. In 2016, ILSI North America published the results of a study evaluating 1,530 food-related chemicals across hundreds of in vitro assays. Their large-scale analyses took a significant step toward characterizing the bioavailability of food-related chemicals, which, in part, helps prioritize chemicals for further safety evaluation. In addition to publishing their data, researchers presented their findings at scientific meetings and conducted training webinars on using ToxCast HTS in food-related chemical evaluations. Sharing of Perspectives on ERA The ILSI Research Foundation, ILSI Japan, and ILSI Korea hosted a set of events in 2016 furthering their longstanding collaboration on environmental risk assessment (ERA). The focus of these events was ERA under conditions of low exposure, such as those experienced during importation of food and animal feed. In Korea, speakers from the United States and Australia highlighted the importance of problem formulation in low exposure risk assessment. Representatives from the Korean Rural Development Administration provided context (history, current practice, and regulatory considerations) for how problem formulation can enhance Korea’s efforts. In Japan, a symposium and workshop involving representatives from the Ministry of Agriculture, Forestry and Fisheries addressed endpoints for ERA, collection of data, and concepts of data transportability. www.ilsi.org Real World Solutions – GE Mosquitos The ILSI Research Foundation and the Foundation for the National Institutes of Health co-organized a workshop to develop a more informed understanding of plausible risks associated with the use of genetically modified mosquitos to control mosquitoborne diseases, and to make recommendations about the research needed to address those risks. International experts on the biology of Anopheles mosquitoes, gene technology, and biosafety came from Brazil; Burkina Faso; India; Kenya; Mali; Mexico; the Netherlands; United Kingdom; United States; Switzerland; and Tanzania. In a pre-Olympics workshop, ILSI Brasil addressed a variety of health and safety concerns of interest to athletes and international visitors, including the high-profile, mosquitoborne Zika virus. Experts from the University of São Paolo provided an overview of national efforts to introduce GE mosquitos to control the spread of Zika. 5 Food Safety ILSI’s food and water safety programs contribute to better prevention, detection, and response to intentional and unintentional contamination of our food and water systems. Food Safety in Taiwan ILSI Taiwan’s programs on food safety risk science and assessment are designed to help ensure all Taiwanese people have access to safe, nutritious food. To achieve this, the branch fosters public-private sector exchange of ideas on the science underlying current risk assessment, risk management, and risk communication practices. It encourages a multisector exploration of the potential of new risk assessment methods. The focus of ILSI Taiwan’s 2016 Annual Meeting reinforced the branch’s commitment to using the latest science to strengthen the safety of Taiwan’s food supply. Prof Junshi Chen, chair of the Codex Committee on Food Additives and executive director of ILSI Focal Point in China, was the keynote speaker. Additional presentations were given by experts from the Taiwan Food and Drug Administration, the National Health Research Institutes, and several universities. Dr. Pinpin Lin, National Health Research Institutes, featured ILSI HESI’s RISK21 approach to risk assessment in her presentation on hazard vs. risk. 6 ILSI Annual Report 2016 Within the ILSI network, ILSI Taiwan is a leader in communication and actively promotes candid, transparent scientific discussion with members of the media. This was demonstrated by Prof Kuei-Jung Ni, Institute of Technology Law of National Chiao Tung University, who provided a unique perspective on communication in his presentation “Speaking Law to Scientists.” The branch hosts several press conferences each year at which journalists, science and health writers, and food and technology bloggers engage with academic experts on topics relevant to the health of the Taiwanese population. The news conference held in conjunction with the 2016 annual meeting focused on dioxin and dioxin-like compounds in the food supply. Detailed data on trends in concentrations of dioxin-like compounds in Taiwanese foods by category were presented. While it was noted that concentration levels were down significantly in most food categories, scientists also explained concerns over flat or even slightly increasing concentrations in certain food categories such as grains, fruits and fats/oils. ILSI Taiwan is a leader in science communication and actively promotes candid, transparent scientific discussion with members of the media. ILSI South Africa Maintains Momentum on Food Microbiological Risk Assessment In 2015, the Food and Agriculture Organization of the United Nations (FAO) and ILSI South Africa coorganized a hands-on food microbiological risk assessment (MRA) training workshop. Held in Namibia, it was the first-ever MRA training held in southern Africa. FAO and ILSI South Africa partnered on MRA training again in 2016; this time with funding from the government of Switzerland. Held in Rwanda, 16 central African nations were invited and 13 participated in an expanded, four-day training program. FAO and ILSI South Africa are already planning 2017’s training event, this time for countries in west African. The Importance of Food Packaging Packaging is an indispensable component of food manufacturing and food distribution processes. It keeps food safe, helps extend shelf life, and gives consumers a range of options for conveniently storing food and preparing meals. ILSI is interested in ensuring the safety and efficacy of new technologies used to improve food packaging. Every four years, ILSI Europe organizes an international symposium on quality and safety of food packaging. Their most recent event, the 6th International Symposium on Food Packaging, focused on innovation. Experts presented on risk assessment of food contact materials (FCM), including renewable and recycled materials; concepts, methods, and tools used to test and evaluate migration of FCMs; and innovations such as “intelligent packaging” involving technology to sense or measure product attributes and shipping environments. The food packaging safety assessment frameworks developed by the European Commission and the US Food and Drug Administration (US FDA) are built on similar principles. ILSI North America held a workshop in 2016 at which several scientists from the US FDA presented their perspectives on issues related to analytical methods for evaluating components of FCMs and contaminant residues from recycled paper, paperboard, and plastics. They highlighted challenges such as lack of standard methods of analysis; standard reference materials; analytical standards for many components of FCM; and standard experimental design for migration tests. www.ilsi.org “Effective food safety and quality management systems are essential not only for safeguarding the health and well-being of people, but also in fostering economic development and improving livelihoods.” FAO, 2015 7 Nutrition and Health ILSI’s comprehensive nutrition and health programs are designed to improve scientific understanding of nutritional requirements throughout the lifecycle; food components that contribute to health beyond basic nutrition; eating behavior; and more. Understanding Dietary Needs in a Diverse Region Southeast Asia is a physically and culturally diverse region. More than 600 million people live there; some in the most globalized urban centers in the world and others in rural areas where development and integration into larger economies has been slow. It is in this context ILSI Southeast Asia Region operates. Over the decades, the branch has worked to improve nutrition and food safety on a regional level while food systems have changed, especially as they have gone from local to global. To do so, the branch has sought to understand and compensate for differences among diverse populations and economic entities. Food composition data must be accurate and current to have clear idea of what people are eating and of the nutritional value of their foods. From this baseline, better nutritional guidelines and food safety policies can be recommended. 8 ILSI Annual Report 2016 In 2016, ILSI Southeast Asia Region organized the symposium “Dietary Intakes: Assessing What We Eat and Evaluating Methodologies.” The symposium was designed to share local experiences and international best practices in dietary assessment methodologies with the goal to identify barriers and opportunities for expanding and improving food composition databases in Southeast Asia. Experts from Australia, Singapore, and the United States presented on methods used in their countries. Researchers and government officials from Indonesia; Malaysia; Thailand; and the Philippines presented data from recent nutrition surveys and what they tell us about diet’s role in various health outcomes in those countries. In addition to providing local diet snapshots, the discussions highlighted gaps in and among methods. Knowing these differences and how they might be bridged will be critical to foster regional harmonization of nutrition recommendations and food safety practices. “The future for research and the health of the public lies in open data and therefore, ILSI North America is pleased to be a part of this significant open data project.” Eric Hentges, Executive Director of ILSI North America ILSI’s Food Fortification Programs Continue to Expand Since 2004, ILSI Japan and the Food and Nutrition Research Institute of the Philippines have worked together to pilot and conduct a market trial of iron and zinc fortified rice. Their efforts are part of ILSI Japan’s Project IDEA (Iron Deficiency Elimination Action), a staple food fortification program active in China; Vietnam; Cambodia; and the Philippines. In 2016, at the end of the successful completion of a large-scale but regional market trial, stakeholders met to outline a strategy for expanding the rice fortification program nation-wide. In late 2016, ILSI-India and ILSI Japan organized a meeting on food fortification programs in Asia and Africa at which the Philippines study was highlighted. ILSI-India and ILSI Japan are using the Philippines experience to determine the feasibility of a similar effort in India. ILSI North America Partners with USDA on Open Data Project In 2016, US Department of Agriculture (USDA) Secretary Tom Vilsack announced the launch of the USDA Branded Food Products Database. This new online tool contains nutrient composition and ingredient information on branded foods and private label data, provided by the food industry, on more than 80,000 (and growing) brand name prepared and packaged foods. The database was the result of a partnership among USDA; ILSI North America; GS1 US; 1WorldSync; and Label Insight. These organizations share a goal to foster access to and use of open data in initiatives designed to improve health. All researchers interested in nutrition and health will find this database useful. It will: • enhance the National Health and Nutrition Examination Survey by more accurately characterizing food selection and nutrient intakes for Americans; • enable nutrition software developers to produce enhanced software so dietitians will be able to better tailor diets to nutritional needs; • enable medical researchers to better link dietary intakes to measures of chronic diseases. www.ilsi.org Micronutrient Supplementation Helps Millions in China In 2001, the Chinese Center for Disease Control and ILSI Focal Point in China began collaborating on the development and testing of a complementary food supplement to alleviate malnutrition in infants and young children in rural areas of China. The supplement, known as Ying Yang Bao, is provided in a soy bean powder base that can be used at home. Three series of intervention trials consistently show Ying Yang Bao significantly reduces anemia and stunting, and improves cognitive development. Ying Yang Bao celebrated 15 years of success in 2016. The program received an additional USD 72 million in support, primarily from the Chinese government, which allows it to expand coverage to 21 rural provinces reaching over 1.4 million at-risk children. 9 Sustainable Agriculture and Nutrition Security ILSI’s programs in sustainable agriculture and nutrition security deal with the challenges of increased food demand and impacts of climate change on food systems through an informed, collaborative approach. 10 ILSI Research Foundation Unites Disciplines Many stakeholders – including researchers; farmers; governments; world health bodies; and others – have recognized for some time that climate change and extreme weather events are threats to our ability to produce sufficient amounts of nutritious food to feed the planet. Complicated linkages among a changing environment, nutrition security, and human health are intensified because of the interconnected nature of the global food system. The ILSI Research Foundation is working to improve our understanding of these complex interactions to better determine how best to adapt so food systems meet nutrition needs in more sustainable ways. ILSI Annual Report 2016 An important step forward in this effort took place in 2016 in Montpellier, France. The ILSI Research Foundation joined academic partners from the University of Washington and Johns Hopkins University to co-host a roundtable discussion titled “Climate Change, Nutrition & Health: Building Collaborative Structures.” The roundtable was held in conjunction with the 6th Global Workshop of the Agricultural Model Intercomparison and Improvement Project (AgMIP), a major international effort linking the climate, crop, and economic modeling communities. Thirty international experts from a variety of scientific disciplines explored whether different types of diets (plant-based vs. animal- and plant-based) impact climate change differently, and conversely, whether climate change impacts dietary patterns and nutrition and health outcomes. They discussed what methods and metrics are needed to better understand relationships among among diets; nutrition; health outcomes; and climate change. Importantly, the group shared ideas on ways the nutrition and climate science communities might better collaborate on these important issues. “We must collaborate across sciences and with other disciplines to achieve sustainability.” Charles Rice, PhD, Kansas State University Charting a Course Forward In the United States, there is a growing demand for nutritious food to be produced in more carbonneutral ways and new research suggests this goal is achievable. However, important questions still need to be answered. For example, what is the permanence of soil carbon reserves and how does one best validate emerging soil carbon protocols? To address these and other important questions, the ILSI Research Foundation organized “C-Quest: Charting a Course for Climate Research in Agriculture” in 2016. Eighty scientists, farmers, and other experts attended the event with the shared goal to prioritize a set of research targets for US agriculture that support the US Department of Agriculture’s building blocks for climate smart agriculture, and integrate existing US field research networks for climate adaptation. C-Quest was co-sponsored by the Foundation for Food and Agriculture Research; the Howard G. Buffett Foundation; Monsanto Company; Soil Health Partnership; USDA; Washington University in St. Louis; and the Sustainable Agriculture Research and Education (SARE) program at the University of Missouri. The ILSI Research Foundation took a multi-sectoral, collaborative approach to planning this workshop, and ensured the C-Quest organizational committee included representatives from the sponsorship groups as well as Field to Market; North American Climate Smart Agriculture Alliance; The Nature Conservancy; and World Wildlife Fund. The top research priority identified by C-Quest participants focused on developing reliable indicators for quantifying soil health. This reflects surging commercial and research interest in promoting robust soil microbial communities, improving cover crop cultivars, and characterizing soil health-related ecosystem services. C-Quest’s summary report, along with the presentations from the workshop, were shared broadly to help inform research and investment strategies in the United States. www.ilsi.org Open Data Leads to Innovation Open data, elemental to identify needs and track progress, are at the center of innovation in agriculture, food security, and nutrition. The ILSI Research Foundation is a strong advocate for open data and has been an early practitioner of data sharing through resources like the ILSI Crop Composition Database. The Research Foundation is pleased to be part of an international effort to greatly expand the use of open data in nutrition modeling through its close collaboration with the Global Open Data for Agriculture and Nutrition (GODAN) initiative. The 2016 GODAN Open Data Summit brought together government representatives; researchers; farmers; students; and leaders from public and private organizations to collaborate on ways to make agriculture and nutrition data open and available, all with a goal to help eliminate world hunger. The GODAN initiative launched two years ago. There are now more than 300 GODAN partners, including the ILSI Research Foundation, working together to build high level policy and institutional support for open data, both in the public and private sectors. 11 Regional Cooperation The initial steps for establishing ILSI and its ultimate incorporation over 35 years ago were made in the United States. Even then, however, ILSI recognized that health and science are borderless concepts and that health decisions are made locally. Global Perspective ILSI’s network is consciously designed so that science – no matter where it is generated – can be applied in national or regional context. safety. They recognized the increasingly interconnected nature of the food systems they share, and wanted to work together to improve food safety harmonization. Today, 16 regional or countryspecific branches, the ILSI Health and Environmental Sciences Institute, and the ILSI Research Foundation work together to provide a flexible mechanism for identifying emerging issues, fostering a harmonized use of science, and building scientific and technical capacity at the local level. Since 2009, their efforts have expanded to include all of east Asia. The 8th BeSeTo meeting, held in 2016, involved ILSI Southeast Asia Region and ILSI Taiwan. It resulted in commitment to a review and assessment of nutrition labeling and health claim requirements currently in place in the region. The study will describe similarities and differences from country to country and how they compare to standards recommended by Codex Alimentarius. Asia ILSI branches in Asia have long been leaders in crossgeography coordination and collaboration. In 2009, ILSI Focal Point in China, ILSI Japan, and ILSI Korea held the first BeSeTo (Beijng – Seoul – Tokyo) meeting; a gathering of stakeholders from the three countries to discuss concerns around food 12 Latin America Latin America is a vast region stretching from the US – Mexico border to the nearAntarctic regions of Argentina and Chile. It includes several countries in the Caribbean. There is immense diversity among the region’s nations in terms of culture, political systems, and economic development. Each country and regions within the ILSI Annual Report 2016 region have unique public health and environmental issues and concerns. On this latter point, however, the ILSI branches in Latin America recognize they share much in common when it comes to addressing human health and wellness and ensuring a safe and sustainable environment. In 2016 and for the first time ever, all ILSI branches in Latin America – ILSI Argentina; ILSI Brasil; ILSI Nor-Andino; ILSI Mesoamerica; ILSI Mexico; and ILSI Sur-Andino – organized a regional annual meeting. Over the course of three days, the branches in Latin America prioritized scientific areas for future collaborative work: comparing and harmonizing food composition databases; building scientific and technical capacity in risk assessment; and better understanding how food science and food technology can improve food safety and nutrition status, and contribute to sustainability of the food supply. www.ilsi.org 13 14 ILSI Annual Report 2016 2016 Board of Trustees Prominent researchers from public and private entities jointly lead ILSI. The individuals who serve on the ILSI Board of Trustees bring a range of expertise, experience, and perspective to their work defining and achieving ILSI’s goals. These individuals are unpaid volunteers who take their scientific and fiduciary responsibilities to the organization seriously. Peter van Bladeren, PhD ILSI President Nestlé Switzerland Professor Alan Boobis, OBE Chair of the ILSI Board of Trustees Imperial College London United Kingdom Todd Abraham, PhD _ Mondelez USA Scott Belanger, PhD Procter & Gamble USA Ary Bucione Dupont Brazil Sushila Chang, PhD Griffith University Australia Michael Doyle, PhD University of Georgia USA Adam Drewnowski, PhD University of Washington USA Professor Dr Gerhard Eisenbrand University of Kaiserslautern Germany Catherine Field, PhD University of Alberta Canada Ernie Harpur, PhD Newcastle University United Kingdom Ivonne Rietjens, PhD Wageningen University The Netherlands Takeshi Kimura, PhD Ajinomoto Co., Inc. Japan B. Sesikeran, MD National Institute of Nutrition India Ik-Boo Kwon, PhD Lotte Company Korea Geoff Smith Nutrition Strategies International Singapore Serrine Lau, PhD Wayne State University USA Josette Lewis, PhD University of California, Davis USA Joanne Lupton, PhD Texas A&M University USA Teruo Miyazawa, PhD Tohoku University Japan John O’Brien, PhD Nestlé Switzerland Timothy Pastoor, PhD, DABT on behalf of Syngenta Crop Protection USA Professor Dr Gerhard Rechkemmer Max Rubner-Institut Germany Professor Lewis Smith University of Leicester United Kingdom Sara Valdéz Martinez, PhD Universidad Nacional Autónoma de México México Ken Wallace, PhD University of Minnesota USA Connie Weaver, PhD Purdue University USA Peter Weber, MD, PhD DSM Switzerland Elizabeth Westring, PhD General Mills, Inc. USA Flávio Zambrone, PhD Planitox Brazil Tracey Reynolds, PhD Monsanto Company USA www.ilsi.org 15 2016 Member and Supporting Companies Generous contributions from the private sector make ILSI’s work to improve scientific knowledge possible. ILSI Argentina Basf Argentina S.A. Bayer S.A. Chacra Experimental Santa Rosa Coca-Cola de Argentina S.A. Danone Argentina S.A. Danone Nutricia S.A. Dow AgroSciences Argentina S.A. DSM Nutritional Products Argentina S.A. Kromberg Fine Chemicals S.R.L. _ Mondelez Argentina S.A Monsanto Argentina S.R.L. Publitec S.A. Editora Syngenta Agro S.A. Unilever de Argentina S.A. ILSI Brasil Abbott Laboratorios do Brasil Ltda. Ajinomoto do Brasil Amway do Brasil Arcor do Brasil Ltda. Arla Foods Arysta Lifescience do Brasil Ltda. BASF S.A. Bayer S.A. Beneo-Orafti Latinoamerica Coord. Regional Ltda. BRF S.A. (Sadia) Cargill Agrícola S.A. Coca-Cola Indústrias Ltda. CTC Centro de Tecnologia Canavieira Danone Ltda. Dow Agrosciences Industrial Ltda. DSM Produtos Nutricionais Brasil Ltda. 16 DuPont Brazil Fábrica de Produtos Alimentícios Vigor S/A Futuragene Brasil Tecnologia Ltda. General Mills Brasil Alimentos Herbalife International do Brasil Ltda. Iharabras S.A. Indústrias Químicas Kellogg Brasil Ltda. Kerry do Brasil Ltda. Masterfoods Brasil Alimentos Ltda. Mead Johnson Nutritional _ Mondelez Brasil Ltda. Monsanto do Brasil Ltda. Nestlé Brasil Ltda. Nutrimental S/A Industria e Comercio de Alimentos Pepsico do Brasil Pfizer Consumer Healthcare Piracanjuba Prodiet Nutrição clínica Ltda. Red Bull do Brasil Ltda. Sanavita Indústria e Comércio de Alimentos Funcionais Ltda. Syngenta Proteção de Cultivos Ltda. Unilever Ltda. Yakult S.A. Indústria e Comércio ILSI Europe Abbott Nutrition Ajinomoto Archer Daniels Midland Company ADM Arla Foods Barilla G&R Fratelli BASF Cargill SE Chr Hansen Cosucra Groupe Warcoing Danone Dow Europe DSM ILSI Annual Report 2016 DuPont Nutrition & Health Firmenich SA FrieslandCampina General Mills Givaudan International AG INDOOR Biotechnologies Ltd Institut Mérieux Johnson & Johnson EMEA KAO Corporation Kemin Health Lavazza S.p.A Lonza Ltd Mars Chocolate Mayr-Melnhof Karton McDonald’s Corporation Mead Johnson Nutrition Merck Consumer Healthcare _ Mondelez International Monsanto Europe Nestlé PepsiCo International Pfizer Consumer Healthcare PIERRE FABRE DERMOCOSMETIQUE Premier Foods Procter & Gamble Red Bull Roquette Frères Sanofi Aventis Group Schwabegroup Sensus B.V. SQM EUROPE N.V. Südzucker Group Suntory Beverage and Food Europe Swiss Quality Testing Services Tate & Lyle Tereos Tetra Pak The Coca-Cola Company Tine SA R&D Ülker Bisküvi Unilever R&D Valspar Corporation WALA Heilmittel Yakult Europe B.V. ILSI Focal Point in China Abbott Laboratories Ajinomoto Co., Inc. Almond Board of California Amway (China) Co., Ltd. BASF (China) Co., Ltd. Cargill Investments (China) Ltd. Carrefour (China) Foundation for Food Safety Coca-Cola (China) Beverages Ltd. COFCO Corporation Danisco (China) Co., Ltd. Dupont Nutrition & Health DSM (China) Ltd. Ferrero China Fonterra Co-operative Group Limited FrieslandCampina General Mills Canada Corporation Givaudan Flavours (Shanghai) Ltd. Groupe Danone Heinz (China) Investment Company Ltd. Herbalife (China) Health Products Ltd. The Hershey Company IFF (China) Ltd. Mars Foods (China) Co., Ltd. McDonald’s (China ) Co., Ltd. Mead Johnson Pediatric Nutrition Institute _ Mondelez Shanghai Food Corporate Management Co., Ltd. Monsanto Biotech Research (Beijing) Co., Ltd. Nestlé (China) Ltd. PepsiCo Asia R & D Center Co., Ltd. Red Bull Rich Products Corporation ROQUETTE Standard Investment (China) Co., Ltd. Starbucks (China) Co., Ltd. Tate & Lyle Tingyi (Cayman Islands) Holding Corp. Unilever China Wrigley Confectionery (China) Ltd. Wyeth Nutritional Co., Ltd. Yum! Restaurants China ILSI Health and Environmental Sciences Institute AbbVie Acea Biosciences, Inc. Alkermes, Inc. ApconiX Ltd. Amgen, Inc. Astellas Pharma Inc. AstraZeneca AB Axiogenesis AG Axion Biosystems, Inc. Axol Bioscience Ltd. BASF Corporation Bayer AG/Bayer CropScience Biogen Idec MA Inc. BioReliance Corporation Boehringer Ingelheim GmbH Bristol-Myers Squibb Company Celgene Corporation Cellular Dynamics International Celsense, Inc. Charles River Laboratories CiToxLAB Covance Laboratories Cyprotex US, LLC Daiichi-Sankyo Co., Ltd. Data Sciences International Dow AgroSciences, LLC Dow Corning Corporation E.I. du Pont de Nemours and Company Eli Lilly and Company Exiqon A/S ExxonMobil GE Healthcare Gentronix Limited Givaudan Schweiz AG GlaxoSmithKline Guangdong IPSyte Biosciences Co., Ltd Hoffmann-La Roche, Inc. ICL-IP America Inc. In Vitro ADMET Laboratories LLC InvivoSciences Inc. Janssen Pharmaceutical Companies Litron Laboratories L’Oreal Corporation Luxembourg Industries Ltd. LyondellBasell Industries Merck & Co., Inc. Monsanto Company NA Nanion Technologies, Inc. Novartis Pharmaceuticals Corporation Novozymes North America Inc. Pfizer, Inc. Pluriomics The Procter & Gamble Company Purdue Pharma L.P. Q-State Biosciences S.C. Johnson & Son, Inc. Sanofi Shell Chemicals, Ltd. Stellar Biotechnologies Sumitomo Chemical Co., Ltd. Syngenta Ltd. Takara Bio Europe AB Takeda Pharmaceutical Company Limited TARA Biosystems, Inc Teva Pharmaceutical Industries Ltd. UCB Biopharma S.P.R.L. Vala Sciences, Inc. VistaGen Therapeutics, Inc. www.ilsi.org ILSI-India Abbott Healthcare Pvt. Ltd. Ajinomoto India Pvt. Ltd. Amway India Enterprises Pvt. Ltd. Bayer CropScience Ltd. Bikanerwala Foods (P) Ltd. Britannia Industries Ltd. Coca-Cola India Pvt. Ltd. Danisco (India) Pvt. Ltd. DSM India Pvt. Ltd. General Mills India Pvt. Ltd. Glanbia India Pvt. Ltd. Herbalife International Pvt. Ltd. Hexagon Nutrition Pvt. Ltd. Hindustan Unilever Ltd. Kejriwal Enterprises Kellogg India Pvt. Ltd. Mead Johnson Nutrition (India) Pvt. Ltd. _ Mondelez India Foods Ltd. Monsanto Holdings India Pvt. Ltd. National Dairy Development Board Nestle India Ltd. Nestle R&D Center India Pvt. Ltd. Pepsico India Holdings (P) Ltd. Roha Dyechem Pvt. Ltd. Sayaji Sethness Ltd. Yakult Danone India Pvt. Ltd. 17 2016 Member and Supporting Companies continued ILSI Japan ADEKA Corporation Ajinomoto Co., Inc. Ajinomoto General Foods, Inc. Amano Enzyme Inc. API Co., Ltd. Asahi Group Holdings, Ltd. BASF Japan Ltd. Bayer Crop Science K.K. Coca-Cola (Japan) Co., Ltd. Dow Chemical Japan Ltd. DuPont Kabushiki Kaisha FANCL Corporation Fuji Oil Holdings Inc. FUJIFILM Corporation Genective Japan Co., Ltd. Ito En, Ltd. Kagome Co., Ltd. Kaneka Corporation Kao Corporation Kewpie Corporation Kikkoman Corporation Kirin Co., Ltd. Knorr Foods Co., Ltd. Kyowa Hakko Bio Co., Ltd. Matsutani Chemical Industry Co., Ltd. Megmilk Snow Brand Co., Ltd. Meiji Co. Ltd. Mitsui Norin Co., Ltd. Mitsui Sugar Co., Ltd. Miyoshi Oil & Fat Co., Ltd. Monsanto Japan Ltd. Morinaga & Co., Ltd. Morinaga Milk Industry Co., Ltd. Nagase & Co., Ltd. Nestlé Japan Ltd. Nichirei Corporation Nippi Inc. Nippon Flour Mills Co., Ltd. NH Foods Ltd. Nippon Suisan Kaisha Ltd. Nisshin Seifun Group Inc. NOF Corporation Ogawa & Co., Ltd. Otsuka Pharmaceutical Co., Ltd. 18 Prima Meat Packers, Ltd. Riken Vitamin Company, Ltd. Rohto Pharmaceutical Co., Ltd. San-Ei Gen F.F.I., Inc. Sapporo Holdings Ltd. Shiono Koryo Kaisha, Ltd. Showa Sangyo Co., Ltd. Suntory Global Innovation Center Syngenta Japan K.K. T. Hasegawa Co., Ltd. Taiyo Kagaku Co., Ltd. Takasago International Corporation The Nisshin OilliO Group, Ltd. Ueno Food Techno Industry, Ltd. Unilever Japan Service K.K. Yakult Honsha Co., Ltd. Yamazaki Baking Co., Ltd. ILSI Korea Amway Korea Ltd. BASF Company Ltd. Bayer Crop Sceince Ltd. CJ Cheiljedang Coca-Cola Korea Daesang Co., Ltd. DOW AgroSciences International Ltd. DuPont Korea Inc. Haitai Confectionery & Food Co., Ltd. Herbalife Korea Co., Ltd. JMC Corporation KOREA YAKULT Lotte R&D Center MARS Korea Monsanto Korea Ltd. Nestle Korea Nongshim Co., Ltd. Pulmuone Co., Ltd. Samyang Corp. Sempio Foods Company SPC ILSI Mesoamerica Alimentos Ligeros de Centroamérica Abbott Nutrition Bimbo de Costa Rica Coca-Cola Company D&PL Semillas DOLE Tropical Products Dos Pinos Grupo DEMASA Mead Johnson _ Mondelez Nestlé Pozuelo ILSI Mexico Abbott Laboratories de México S.A. de C.V. Corporativo Bimbo S.A. de C.V. Effem México, Inc. y Compañias S. en N.C. de C.V. METCO S.A. de C.V. _ Mondelez México S. de R.L. de C.V. Nestlé de México S.A. de C.V. Pepsico México R&D Savory S. de R.L. de C.V. Siaag S.A. de C.V. (Coca-Cola de México) Yakult, S.A. de C.V. ILSI North America Abbott Nutrition Ajinomoto North America, Inc. Applied Food Sciences, Inc. Archer Daniels Midland Company BENEO-Group Biofortis Clinical Research Campbell Soup Company Cargill, Incorporated The Coca-Cola Company Danone Nutricia Research Deibel Labs Dr Pepper Snapple Group DSM Nutritional Products ILSI Annual Report 2016 DuPont Nutrition & Health Egg Nutrition Center Firmenich General Mills, Inc. Heartland Foods Herbalife Inernational of America, Inc. The Hershey Company Ingredion Incorporated International Tree Nut Council Kellogg Company Kemin Foods L.C. Kerry Ingredients and Flavours LTD Kraft Heinz Company Leprino Foods Mars, Incorporated _ Mondelez International Monsanto Company Monster Energy Company National Dairy Council Nestlé USA Ocean Spray Cranberries, Inc. PepsiCo, Inc. Red Bull GmbH Senomyx, Inc. Starbucks Coffee Company Tate & Lyle Unilever The Valspar Corporation Welch’s ILSI North Andean Abbott Alfonzo Rivas Alimentos Polar Alpina Alquería Amway Cargill Cervecería Polar Coca Cola Danisco/Dupont Danone DSM Herbalife Ingredion Kellogg Lafrancol Mead Johnson Meals _ Mondelez Monsanto Nestlé Omnilife Parmalat PepsiCo Postobón Pronaca Seatech TONI Unilever ILSI South Africa Bayer (Pty.) Ltd. Clover South Africa Coca-Cola S.A. Danone Southern Africa DSM Nutritional Products Kellogg Company South Africa Mars Africa Monsanto S.A. Nestlé (South Africa) (Pty.) Ltd. Tate & Lyle Unilever S.A. (Pty.) Ltd. ILSI South Andean Coca-Cola DSM Dupont _ Mondelez Monsanto Nestlé Tresmontes Lucchetti ILSI Southeast Asia Region Abbott Nutrition R&D Ajinomoto SEA Regional Headquarters Co. Ltd. BASF South East Asia Pte Ltd. Bayer CropScience Pty Ltd. BENEO Asia Pacific Pte Ltd. Campbell Arnotts Suntory Beverage & Food Company Japan Coca-Cola Southeast Asia Services Co., Ltd. DSM Nutritional Products Asia Pacific Pte. Ltd. Fonterra Co-operative Group Limited FrieslandCampina Development Centre AMEA Pte. Ltd. General Mills Herbalife International Singapore Pte. Ltd. Kellogg Asia Pacific Pte. Ltd. MARS Incorporated Mead Johnson Nutrition Cadbury Enterprises Pte. Ltd. _ (Mondelez International) Monsanto Singapore Co., (Pte.) Ltd. Nagase & Co, Ltd. Nestle R&D Center (Pte.) Ltd. Nutricia Research Singapore Nutrition Strategies International PepsiCo Services Asia Ltd. PT Nutrifood Indonesia Simplot Australia Pty. Ltd. Syngenta Asia Pacific Pte. Ltd. Tate & Lyle Unilever South East Asia Australasia U.S. Dairy Export Council Yakult Honsha Co., Ltd. Yeo Hiap Seng Ltd. ILSI Taiwan Abbott Laboratories Services Corporation, Taiwan Branch. AGV Products Corp. Ajinomoto Taiwan Inc. Allied Biotech Corp. Amway Taiwan Company Limited BaFang YunJi International Co., Ltd. Bayer Taiwan Co., Limited Cerebos International Health Ltd., Taiwan Branch Chien Cheng Trading Co., Ltd. China Grain Products Research & Development Institute Coca-Cola Far East Ltd. Taiwan Branch Creation Food Co., Ltd. Dupont Taiwan Limited Gemfort Corporation Grape King Inc. Great Wall Enterprise Co., Ltd. Herbalife Taiwan Inc., Taiwan Branch Hey-Song Corporation Hsin Tung Yang Co., Ltd. I Lan Foods Industrial Co., Ltd. K&K Foods Ltd. King Car Food Industrial Co., Ltd. Kuang Chuan Dairy Co., Ltd. Laurel Enterprises Corporation Lian Hwa Foods Corporation Mars Taiwan McDonald’s Restaurants (Taiwan) Co., Ltd. www.ilsi.org Monsanto Far East Ltd., Taiwan Branch NAGASE (Taiwan) Co., LTD Namchow Chemical Industrial Co., Ltd. Nestle Taiwan Ltd. Nu Skin Taiwan Nutritec-Enjoy Corporation Nutritec-Enjoy Nutrition Center Inc. (NENC) Orient EuroPharma Co., Ltd. PepsiCo Foods Taiwan Co., Ltd. Pfizer Limited Standard Foods Corporation Taiwan Chlorella Manufacturing Co., Ltd. Taiwan Sugar Corporation Toong Yeuan Enterprise Co., Ltd. Uni-President Enterprises Corporation Universal Integrated Corporation Vedan Enterprise Corporation Vitalon Foods Company Wei Chuan Foods Corporation 19 2015 Financial Snapshot Combining Resources to Achieve More ILSI branches and the ILSI Research Foundation are separate legal entities affiliated with ILSI corporate through charter agreements. The branches have independent accounting departments and follow accounting principles standard in their home countries. An aggregate of financial information for ILSI corporate, ILSI branches, and the ILSI Research Foundation is presented here. Although ILSI corporate does not audit the information submitted by the branches for this report, it is a best estimate of global financial activity. ILSI & Affiliates Revenue Member Support $ 11,697,026 Grants & Contributions 3,277,359 Government Grants 1,042,707 Interest & Dividend Income 676,514 Publications378,698 Conference Registration 318,438 Other Income 319,739 Total Revenue $ 17,710,481 Expenses Program Staffing & Support $ 5,533,324 Scientific Meetings 3,757,351 General Administrative 3,491,903 Research2,621,729 Publications984,813 Governance895,868 Development400,653 Total Expenses 20 2015 $ 17,685,641 Change in Net Assets from Operations Change in Fair Value of Investments $ 24,840 Change in Net Assets $ -596,619 -621,459 ILSI Annual Report 2016 Contact Information ILSI www.ilsi.org Suzanne Harris, PhD Executive Director ILSI Argentina www.ilsi.org/Argentina Patricia Torres Branch Coordinator ILSI Research Foundation www.ilsi.org/ ReseachFoundation Morven McLean, PhD Executive Director ILSI Brasil www.ilsi.org/Brasil Flavia Goldfinger Executive Director ILSI Europe Celebrating 30 Years www.ilsi.org/Europe Diána Bánáti, PhD Executive Director ILSI Focal Point in China www.ilsi.org/China Junshi Chen, PhD Executive Director ILSI Health and Environmental Sciences Institute www.hesiglobal.org Syril Pettit Executive Director ILSI-India www.ilsi.org/India Rekha Sinha Executive Director The International Life Sciences Institute (ILSI) is a nonprofit, worldwide organization established in 1978 to advance scientific understanding of nutrition, food safety, toxicology, risk assessment, and the environment. ILSI brings experts from the private and public sectors, who work together to improve the science used to ensure human and environmental health and safety. ILSI Japan Celebrating 35 Years www.ilsi.org/Japan Atsushi Uzu Executive Director ILSI North Andean www.ilsi.org/NorthAndean Olga Lucía Mora Gil Executive Director ILSI Korea www.ilsi.org/Korea Ji-Young Lee Executive Director ILSI South Africa www.ilsi.org/SouthAfrica Lucia Anelich, PhD Executive and Scientific Director ILSI Mesoamerica www.ilsi.org/Mesoamerica Hannia León León, PhD Executive Director ILSI South Andean www.ilsi.org/SouthAndean Cristina Cisternas Branch Coordinator ILSI Mexico Celebrating 25 Years www.ilsi.org/Mexico J. Eduardo Cervantes Executive Director ILSI Southeast Asia Region www.ilsi.org/SEA_Region Yeong Boon-Yee Executive Director ILSI Middle East www.ilsi.org/MiddleEast Maysm Nezar Mohamad General Secretary ILSI Taiwan www.ilsi.org/Taiwan Jenny (Yueh-Ing) Chang, PhD Executive Director ILSI North America www.ilsi.org/NorthAmerica Eric Hentges, PhD Executive Director International Life Sciences Institute®, ILSI®, and the ILSI logo image of concentric circles are trademarks of ILSI. ©2016 International Life Sciences Institute All Rights Reserved All photographs ©dreamstime.com For information about ILSI, contact: International Life Sciences Institute 1156 Fifteenth Street, NW Suite 200 Washington, DC 20005 USA www.ilsi.org [email protected] International Life Sciences Institute 22 1156 15th Street, NW 1.202.659.0074 t 1.202.659.3859 f Suite 200 www.ilsi.org Washington, DC 20005 ILSI © 2016 Annual International Report 2016 Life Sciences Institute
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