Reproduced by Sabinet Gateway under licence granted by the Publisher (dated 2012) C L I N I C A L CASE R E V I E W MANAGEMENT PROBLEMS IN GENERAL PRACTICE A 50-year-old woman with a swollen, tender foot Clinical problem We present here a clinical problem encountered in general practice together with a commentary from an expert in the field. If you meet an interesting or puzzling case you. would like considered in this aeries please send it to us. Commentary • In a d d r e s s i n g a p r e s u m a b l y menopausal woman with a history such as this, one would need to consider osteoporosis, diabetic neuropathy, gout and the most likely cause — a sprain of mildly osteoarthritic t a r s o m e t a t a r s a l joints. The X-ray could well show no sign of such arthritic changes, A technetium bone scan woiild reveal microfractures in the midfoot if the injury was due to osteoporosis, or occiilt fractures associated with midtarsal disruption if due to neuropathy. Possibly, the localized periarticular changes of gout or early tarsal osteoarthritis would be seen. A uric acid test and, if indicated, a 24-hour urine test would eliminate the possibility of gout if there was a suspicion of this condition. U!"inalysis and possibly a random blood sugar analysis would confirm or exclude a diagnosis of late Commentary by Professor Edward Bates, MB BS, FRCS, FRACS, associate professor of paediatric orthopaedics. University of New South Waies, and Chairman, department of paediatric surgery. Prince of Waies Chiidren's Hospital, Sydney, New South Wales, Australia. This article was written specially A 50-year-old w o m a n presents with a swollen, tender foot. Her foot h a s b e e n this w a y for around six w e e k s since s h e s t u b b e d h e r t o e . At n o t i m e h a s t h e d i s c o m f o r t b e e n f o c u s e d in t h e toe; rather it is in t h e m i d d l e of t h e foot over all five metatarsals. No abnormality is f o u n d o n Xray but there is a definite swelling w h i c h is improved by resting the foot. Is this related to the initial injury? H o w should this condition be treated? onset diabetes, although most cases of neuropathic feet do not present acutely and have a fairly gradual onset of symptoms. All of these conditions would be associated with swelling and tenderness. Disuse and dependency would aggravate this swelling. If the medical alternatives to simple midfoot sprain have been excluded, traumatic aggravation of subclinical osteoarthritic joints would be the most Kkely and certainly the most common cause of this not uncommon, but rather vague, clinical scenario. Treatment at six weeks shoiild comprise analgesics, probably slow release NSAIDs and/or paracetamol, in conjunction with elevation and compression bandaging of the foot and a physical therapy programme to restore strength and mobility. A moulded sponge-rubber inner sole with medial arch support might provide symptomatic relief This condition is related to the stubbing of her toe. I do not feel that the ubiquitous reflex sympathetic dystrophy syndrome shoiild be considered in this clinical context. • YOUR INF0...F0R YOUR INF0...F0R YOUR INFO. Melanoma vaccine improves survival Four-year survival appears to be significantly better among patients with bull<y but surgically resectable nodal metastases of malignant melanoma who are treated with an investigational melanoma vaccine. In a study of 62 patients who received the vaccine after standard lymphadenectomy, 47% had no relapses after four years, and 58% survived four years. This compares with a 20 to 25% survival in patients who were treated with surgery alone. Patients older than 50 had a better four-year survival rate than those younger (66 vs 46%). 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No. Kclotx-ive I: Kdiv J, tJ. cl .il l.ur I t 'liii I'li.innaiol IMX'i;
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