Patient information (Insemination treatment) 1 Contents WELCOME TO THE FERTILITY CLINIC ....................................................................................................................... 4 Staff ........................................................................................................................................................... 4 Contact ...................................................................................................................................................... 4 BEFORE THE TREATMENT ..................................................................................................................................... 5 Cervical screening test ............................................................................................................................... 5 Female ....................................................................................................................................................... 5 Male ........................................................................................................................................................... 5 WHO CAN BE TREATED BY INSEMINATION? ............................................................................................................. 6 The treatment ............................................................................................................................................ 6 PROCEDURE OF INSEMINATION TREATMENT............................................................................................................ 6 How to start-up treatment? ...................................................................................................................... 6 The term ”day of cycle” ............................................................................................................................. 7 Insemination by hormone treatment ........................................................................................................ 7 Insemination without hormone treatment ................................................................................................ 7 Stages in an insemination procedure ........................................................................................................ 7 First day of control (around day 12 of the cycle) ....................................................................................... 7 DAY OF INSEMINATION ........................................................................................................................................ 8 Semen sample ............................................................................................................................................ 8 USE OF DONOR SPERM ........................................................................................................................................ 8 CHOICE OF DONOR ............................................................................................................................................. 8 Anonymous donor...................................................................................................................................... 8 Non-anonymous donor .............................................................................................................................. 8 Remember when you buy donor sperm: .................................................................................................... 9 Known donor............................................................................................................................................ 10 HOW IS CO-MATERNITY DETERMINED? ................................................................................................................ 10 What should I do if I need to determine co-maternity?........................................................................... 11 THE INSEMINATION .......................................................................................................................................... 11 ACUPUNCTURE AND FERTILITY TREATMENT ........................................................................................................... 12 PREGNANCY TEST ............................................................................................................................................. 13 Positive test.............................................................................................................................................. 13 Negative test............................................................................................................................................ 13 Pregnancy scan ........................................................................................................................................ 13 Risk of miscarry ........................................................................................................................................ 13 Pregnancy outside the uterus .................................................................................................................. 13 End of procedure...................................................................................................................................... 13 NUCHAL TRANSLUCENCY SCAN............................................................................................................................ 14 Purpose .................................................................................................................................................... 14 Backgrond ................................................................................................................................................ 14 Advances of nuchal translucency scan. ................................................................................................... 15 Recommendation..................................................................................................................................... 15 Procedure................................................................................................................................................. 15 NIFTY ............................................................................................................................................................ 15 2 The test is offered pregnant women who:............................................................................................... 16 EMOTIONAL STRAIN .......................................................................................................................................... 16 COMPLICATIONS, SIDE EFFECTS, AND RISKS ........................................................................................................... 16 Hormone treatment - common side effects............................................................................................. 16 Too many follicles - Ovarian Hyperstimulation Syndrome ...................................................................... 16 Hormone treatment and ovarian cancer ................................................................................................. 16 Twin Pregnancy ....................................................................................................................................... 17 EXPENSES FOR THE IUI TREATMENT ..................................................................................................................... 17 MEDICAL EXPENSES .......................................................................................................................................... 17 FUTURE .......................................................................................................................................................... 17 THE NATIONAL ASSOCIATION FOR THE INVOLUNTARY CHILDLESS.............................................................................. 17 MEDICATION AND SIDE EFFECTS ........................................................................................................... 18 DIFFERENT TYPES OF MEDICATION IN CONNECTION WITH TREATMENT AT THE CLINIC: .................................................. 18 3 Welcome to the fertility clinic Ciconia is a private fertility clinic situated in Aarhus, Denmark. At Ciconia we are specialized in all manner of modern fertility treatments. Our treatments are always based on the individual patient’s previous experiences and needs. All members of staff at Ciconia have many years of experience and are looking forward to welcoming you. There is no waiting time to start a treatment. This guidance is supplementary to the information given orally during the treatment and the information available on our website www.ciconia.dk You are more than welcome to contact us for further information on phone 0045 8627 7626 or by e-mail [email protected]. For opening hours please visit our homepage www.ciconia.dk In case you have not yet decided whether or not to start a treatment, we offer a free, non-committal conversation with one of our doctors, who based on your needs and previous experiences, the doctor will assess what kind of treatment would be the best for you. In Denmark it is within the law to treat singles, homosexuals and lesbian women, who have not turned 46 years yet. Staff Karsten Petersen, Medical Director and Anette Gabrielsen, Head of the laboratory, handle the day-to-day management. The other members of staff include doctors, nurses, biomedical laboratory technicians, medical secretaries and customer service assistants. We offer a professional treatment in a safe and welcoming environment. We emphasise that your fertility treatment becomes a personal and positive experience that you will not forget. Contact Karsten Petersen is the doctor you will meet for the non-committal conversation before the treatment. Moreover, he will be the one responsible for scheduling your treatment, but he will not necessarily be your doctor for all examinations. 4 Before the treatment HIV and hepatitis test from the woman and eventually the man The law requires all to be tested against AIDS and infectious hepatitis before starting treatment. According to the Fertility law we are required to demand tests against HIV, hepatitis B (HBsAG and Anti-HBc) and hepatitis C (Anti-HCV-Ab) both from the woman and man before we start up the fertility treatment. Therefore, when the fertility patients begin the treatment, we need a copy of the original result of the above-mentioned tests, which all have to be negative. The results should be no more than three month old at start-up of the treatment. Hereafter they are valid for 24 months. For payment you can have the tests done at Ciconia. Cervical screening test The woman should present results from a cervical screening test (routine treatment against uterine cancer). The test should not be older than two years. Before the treatment start-up it can become necessary to do some previous examinations. Female HSU (Water scan + 3D scan) By water scan it is possible to survey the passage through the egg conductors and the uterus, and by means of a long thin catheter lead through the cervix uteri it becomes possible to inject salty water into the uterus. Hereby you get an impression of the shape of the uterus and explore if there are polyps or muscular nodosity, which can prevent pregnancy. Moreover we can detect that there is passage in both egg tubes. The examination is done without anesthesia and if necessary non-prescription medicine can take the pain afterwards. Male We will recommend an estimation of the male partner’s semen sample, if there is no previous estimation. The semen sample can be produced at the clinic or from home, however the sample should not be more than one hour old when it is handed in, and in the meantime it should be kept the same temperature as the body temperature. It is important that before the semen sample is produced there has been not been any ejaculation within the last three days. On the basis of the above-mentioned examinations the doctor can estimate what treatment will be the best suitable for you. 5 Who can be treated by insemination? Intrauterine Insemination (IUI) is the most simple procedure to treat involuntary childlessness We will recommend IUI in cases where there is passage in the uterine tubes and normal or moderate reduced semen quality. Approximately 30-40 % couples are having a baby after 1-3 IUI treatments. If you do not become pregnant by insemination in vitro fertilisation (IVF) treatment is a possibility. If the man does not have any sperm cells the couple can choose insemination with a donor. Also single women and women in lesbian relationships, who do not have normal uterine tubes function, can choose insemination with a donor. Hormone supplement and insemination can optimise the chance to become pregnant, because the woman mature 1-3 eggs, the ovulation is scheduled and the semen sample is being cleaned and transferred to the uterine cavity and the semen sample is deposited into the tubes. The treatment Two methods of treatments with insemination: Treatment with the male partner’s semen (IUIH) Treatment with donor semen (IUID) Procedure of insemination treatment How to start-up treatment? When your menstruation starts please contact the clinic by phone or email [email protected] to receive further information as hormone stimulation and make a scanning appointment. 6 The term ”day of cycle” At Ciconia we have a term called ”day of cycle” for example we say “the first day in your cycle”, which refers to the first day you start to bleed in your period. Spotting some couples of days before your menstruation begins should not count in. Insemination by hormone treatment The first or second day of your menstrual cycle please call us and book an appointment. The appointment should be placed on the 12th day in your cycle. From day 3-7 in your cycle please take two tablets (Pergotime) in order to mature more eggs. Occasionally, you can be advices to take injections (FSH = Follicle-stimulating hormone) on day 8, 9 and 10 in your cycle. Insemination without hormone treatment If the woman’s fertility is normal the insemination can happen without hormone treatment in other words it can happen in an unstimulated cycle. Stages in an insemination procedure First day of control Ultrasound scan on the 12th day in your cycle Insemination On the basis of the results from the scan the insemination is planned within the days 10-12. Pregnancy test Is taken within 14 days after the insemination First day of control (around day 12 of the cycle) At this day the doctor will scan you to estimate if one or more follicles have grown (follicles are blebs of fluid). The size of the follicle and the thickness of the mucous will be measured in order to plan the insemination. The egg is mature when the follicle is about 18 mm in diameter. Therefore you must take an ovulating injection to secure that the ovulation takes place. All scans are carried out vaginal. 7 Day of insemination Semen sample When you arrive at the clinic a member of staff will welcome you and direct the man to the semen sample room. He must produce a semen sample the same day (remember to write both the woman’s and man’s name and personal identification numbers on the sample cup). Furthermore, a note stating the names and the social security numbers of both the man and the women alongside the man’s personal signature must be submitted. Sometimes the man is not able to produce the semen sample due to the circumstances. This is normal. Therefore we offer Viagra, please feel free to ask at the reception if necessary. It is important that there has been not been any ejaculation within the last two-three days when the semen sample is produced. The sample will be placed in a small cabinet next to the laboratory. If you can manage to drive to Ciconia from home in less than one hour, you can produce the semen sample at home and bring it to Ciconia in a sample cup. Remember the sample should be kept the same temperature as body temperature. Use of donor sperm Many couples will consider use of donor sperm, if treatment with the male partner’s semen cannot be advised because of no sperm cells in the semen sample or poor quality of the semen. Moreover donor sperm is used in treatments of single women and women in lesbian relationships. According to law doctors in Denmark are now allowed to treat patients with semen from anonymous and non-anonymous sperm donors and also from a known donor. Choice of Donor Anonymous donor Anonymous donors with a Basic profile ONLY provide information on eye colour, hair colour, height and weight. On the basis of health professional reasons information about the donor’s blood type can be collected if necessary. The donation is completely anonymous and it is not possible to receive further information about the donor. Non-anonymous donor According to the Fertility law by 1st of October 2012 all types of donations with more information than the Basic profile are defined as non-anonymous donations. This include: Extended donor profile include more information than the basic profile (the sperm donor's background, education, family background, interests, hobbies etc.) However it does not state the donor’s identity. Open donor: When the child turns 18 it is possible to inform him/her of the donor’s identity, if he/she make an application to the semen bank. 8 At Ciconia we have a small store of anonymous donor sperm having the most average Scandinavian characteristics (Basic profile). If you would like a donor from our store, we will do our utmost to match the donor with your wishes, here eye colour will have first priority. If you have specific wishes we will be pleased to help you find the right donor. You only have to then contact us in good time before the treatment starts. Moreover you are more than welcome to contact the semen bank yourself in order to find the right donor. It is again important to contact the semen bank early to make sure we have the semen sample ready for time of treatment. Primarily we collaborate with the semen bank Cryos (www.cryos.dk). However, it is possible to use other semen banks as long as you can have documentary evidence that the semen bank has authorised tissue establishment. Remember when you buy donor sperm: At Ciconia we will recommend you to buy one sperm straw ICI MOT20 or one sperm straw IUI MOT10 per insemination/IVF treatment. Several straws can be ordered at the same time. At Ciconia we can store them while the treatment proceeds. However, please be aware that the semen in excess cannot be returned neither by Ciconia nor the semen bank. Moreover, you are able to reserve plenty of sperm from the donor you choose and have it delivered continually to make sure that the donor’s sperm does not gets sold out during the treatment. Please remember to request the sperm at least 3 weekdays before the treatment. Conveyance can be ordered with dry ice or nitrogen. If you collect the semen please fill in a note about delivery authorisation (ask the at the semen bank). Furthermore you should please consider if you would like to reserve semen for having children in the future. Read more follow the link below https://dk-da.cryosinternational.com/donorsaed/reservation-af-donorsaed/ Code to receive price reduction at the semen bank Cryos: CICO8855 The health of the donors are tested regularly, for instance for AIDS and hepatitis. According to the guidelines of the National Board of Health, Denmark, we have, however, to note: "AIDS is a very serious contagious disease that destroys the body defence system against infectious diseases and some cancer tumours. The disease is caused by a virus that can occur for instance in semen. As far as possible it has been ensured that the donors have not had a behaviour that implies a risk of being infected with HIV. In addition to this, donors are tested for the HIV infection before approval by means of a blood sample. The sperm may not be used before it has been frozen for at least six months, and a new blood sample has been taken from the donor testing for the HIV infection to rule out that the donor has generated antibodies against HIV in the period of time. Despite these precautionary measures, a minimal risk of transmitting HIV through an insemination cannot be ruled out." “When choosing a donor the risk, that inheritable diseases, deformities, etc. are passed on, is attempted to be decreased by using donors, who have informed, that these risks of inheritance are not of their 9 knowledge, and health care personnel has questioned and examined the donor regarding this matter. However, despite these cautions, not risk of inheritance can be eliminated. If contrary to expectations there is something the matter with your child when he/she has been born or during the first years of life, and this is something that may be inheritable, it is very important that you report back to the clinic, so that decisions regarding the donors activity can be made.” To conclude, a donor from a semen bank is tested against various diseases and according to hereditarily diseases it is more secure to use a donor. However, there are no guaranties against these diseases, since some of them are very complex and rare. It is very important to understand and accept this before using a donor. Known donor By the end of 2013 it became possible to use a known donor. A known donor is a donor who you know at the time of donation. The known donor must take a blood sample to be tested against HIV, hepatitis B and C and syphilis and submit a urine sample to be tested against Chlamydia. Moreover, an interview with the donor should be made with questions concerning health and hereditarily diseases in the family. Donor should on the basis of the above-mentioned be approved. The receiver of the sperm should also approve the donor. Cryo-preserved sperm will be used for the treatment. Testing, determining and cryo-preserving will happen at Ciconia and the receiver of the sperm will pay for it. Please be aware use of known donor implies that the known donor will have paternity unless the heterosexual or lesbian couple sign the paper regarding paternity and co-maternity. A single woman using a known sperm donor always implies that the donor will have the paternity. New regulations about co-maternity became effective from 1st of December 2013. The new regulations cause to equal rights between couples with same and different genders when the paternity/co-maternity should be determined. The new regulations cause for example that the co-mother has the same rights and obligations to the child. Furthermore, the new regulations imply that if two women have a child together by artificial insemination the woman that is not the mother will become co-mother to the child automatically. In the new regulations artificial insemination is called assisted reproduction even though it is referring to the same. Please be aware, that when choosing a known donor - a donor that has is not anonymous - the donor will be regarded as the father of the child. The donor, the mother and the mother’s partner (wife, registered partner, or girlfriend) can agree that the donor will not be stated as the child’s father. Instead the mother’s partner will be registered as co-mother. How is co-maternity determined? Co-maternity can only be determined if two women have a child together using artificial insemination. Pregnancy achieved using other methods is not valid, if a woman wishes to have co-maternity. To determine co-maternity, the procedure must be initiated before the treatment with artificial insemination. The State Administration will process cases regarding co-maternity. 10 In order to determine co-maternity the mother to-be must give her consent in writing to the treatment, and it must be probable that a child is the result of that treatment. Please be aware that consent must be given and available before the treatment is started. If the sperm donor is know and not anonymous, the sperm donor must also give his consent in writing to the treatment before it is initiated. Furthermore, the treatment must be conducted by authorised healthcare personnel or under the responsibility of a healthcare authorisation. It does not have any influence whether the treatment is conducted by a private organisation or a public organisation. However the treatment must be performed in accordance with the regulations in the law regarding assisted reproduction. What should I do if I need to determine co-maternity? Before the treatment with artificial insemination is begun, you and your partner must fill out a form, which you will find at the State Administration’s website: www.statsforvaltningen.dk. There are two different form depending on your situation. When you have filled out and signed the form, it must be handed in to the healthcare personnel at place, which you have chosen for the treatment. They must also sign it and give you a copy. At the child’s birth, the healthcare personnel will pass the form on to the State Administration, who will handle the case. The insemination At the insemination the purified semen is put into the uterus through a thin smooth plastic tube. The treatment is without pain and only takes a few minutes. There are no precautions after the insemination so you are aloud to go home right away. It is normal that some fluid will come out the following hours. If you wish acupuncture is possible after the insemination. 11 Acupuncture and fertility treatment A huge development within methods of fertility treatments has happened during the last 20 years. However, not before recently alternative treatment methods as acupuncture have been taken into account. The Chinese people have trough ages used acupuncture as part of the treatment of childless couples. An on the basis of their knowledge acupuncture is used as supplementary to IVF and IUI treatments. Research from Sweden and Germany have proven a physical effect from acupuncture, which means that acupuncture can contribute to a successful IVF treatment. Numbers from the German research show an increase from 26,3 % to 42,5 % in the numbers of pregnancies registered with use of acupuncture as supplementary to IVF treatments. A research conducted in Denmark proves the numbers. Acupuncture can optimize fertility treatment since it: Increases blood circulation in the uterus and improve the mucous membrane so the egg can better stick to it Reduces side effects of the hormones such as headache, vertigo etc. Counterbalances the body and relax the uterus Strengths the immune system Relaxes the body Read more here: http://www.bmj.com/content/336/7643/545.full http://www.fertstert.org/article/S0015-0282(06)00212-3/abstract On the basis of the above-mentioned we have chosen to offer acupuncture at Ciconia both for IVF and insemination treatments. The acupuncture will take place the same day as the eggs will be put up or the insemination. 17 needles will be placed at hands, feet, legs, the head and stomach. Side effects from the acupuncture are rare. However, short-term tiredness, thirst or a small bleeding from the area where the needle was placed can happen. 12 If you are interested in acupuncture in connection with your treatment, please inform a member of staff in order to let us plan your procedure. Pregnancy test 14 days after the insemination you can take a pregnancy test. The 14 days can feel long and it is normal to have both positive and negative thoughts in the meantime. Even though bleeding can occur you can still be pregnant. Therefore it is always our advise to take a pregnancy test. Positive test If the pregnancy test is positive please contact the clinic to book an appointment for scan in pregnancy weeks 7. -8. Approximately five weeks from the insemination. Negative test If the test is negative we will kindly ask you to call us both according to further treatment and for our statistics. Pregnancy scan Three weeks from the positive pregnancy test we will make a virginal ultrasonography. It can show if the pregnancy is within the uterus and if the embryo is growing and that the heart beats. Moreover, the scan can show if there should be more than one embryo. Risk of miscarry As in normal pregnancies 15-20 % of all women miscarry. In 2-3 % of all cases a pregnancy will take place outside of the uterus. Pregnancy outside the uterus A pregnancy outside the uterus often placed in the uterine tubes cannot be accomplished and will often be removed by a laparoscopy. End of procedure You will end your treatment procedure at Ciconia if everything is all right. 13 Nuchal translucency scan A nuchal translucency scan is a sonography of the 12-week-old embryo to estimate the risk of Down’s syndrome. From the age of the pregnant it is possible to estimate the risk of Down’s syndrome. Moreover, research show that embryos with Down’s syndrome have a nuchal fold, which can be proven by nuchal translucency scan in pregnancy weeks 12 and 13. The combination of the results from the nuchal translucency scan and the age of the pregnant woman can bring to an exact estimate of the risk for Down’s syndrome than only estimating from the age of the woman. The nuchal translucency scan can be combined with a blood test, what we call “a double test” to estimate the risk of Down’s syndrome even more precise. Therefore our advice to all our patients is to choose “the double test” no matter of the pregnant woman’s age. Recent research shows that the number of children born in Denmark with Down’s syndrome has doubled in the last 10 years. Half of the women who gave birth to the children were under 35 years. Purpose A pregnant woman under 35 years can choose to measurement of the nuchal fold to estimate if there is an increased risk of Down’s syndrome even though she is young. A pregnant woman between 35 and 40 years old can choose the measurement of the nuchal fold to estimate is there is a reduced risk of Down’s syndrome so she can avoid tests of the amniotic fluid and the placenta. A pregnant woman above 40 years can choose the measurement of the nuchal fold to find out the risk of Down’s syndrome is lower compared to her age. Even with a normal nuchal fold there is an inconsiderable risk of Down’s syndrome in this age group. Backgrond Most embryos with Down’s syndrome have a nuchal, which is above 2, 5 mm. The reason is unknown. The nuchal fold can be measured by ultrasound when the embryo is between 11 to 14 weeks old. A nuchal translucency scan earlier than week 11 will result in an imprecise scan, because the embryo is too small. A scan after week 14 makes it difficult to see the nuchal fold, which probably is because of the natural fat layer, which is being produced after week 14. Embryos with heart diseases might also have a thick nuchal fold, which can be due to swelling because of bad blood circulation. Embryos that are healthy often have a nuchal fold, which is 1, 5 mm. or smaller. However, a small amount of all healthy embryos have a nuchal fold that is 2, 5 mm or more. In these cases the nuchal fold is fine. The risk of Down’s syndrome and heart disease is bigger the thicker the nuchal fold is. The majority of embryos with nuchal folds at for example 3 mm are healthy, while majority of embryos having nuchal fold at 5 mm are not healthy. 14 Advances of nuchal translucency scan. You will get a result right away. In most cases there are no need for further testing of the amniotic fluid and the placenta. The method discovers two out of three embryos having Down’s syndrome. Recommendation The choice of having a nuchal translucency scan of the embryo and measure it for other serious diseases is based on attitudes, feelings, religion, ethics etc. Therefore the choice is very personal. We have based on our experiences chosen to advise all pregnant women having nuchal translucency scan of their embryos. Normally, we advise women above 40 years to test the amniotic fluid and the placenta. Procedure First of all we will start by talking about the principles for the examination. Normally, the scan will be introduced by a scan on the stomach and afterwards virginal. Hereafter, we will discuss the results in order to make you able to take a decision about testing the amniotic fluid and the placenta. This is normally done at the hospital. NIFTY Now it is possible to screen against Down’s syndrome and other chromosome divergences based on a blood test from the pregnant woman (NIFTY). By this test the genes of the embryo is analyzed. The genes circulate in the mother’s bloodstreams. At this point of time there is tested against trisomy 21 (Down’s syndrome), trisomy 18 (Edward’s syndrome) and trisomy 13 (Patau’s syndrome) and X- and Y-chromosomes deciding the gender of the child. By all trisomies a majority of chromosomes are available and therefore an increased amount of specific DNA. The test can be taken after 10 weeks of pregnancy and there are no risks of provoking miscarry. More than 200.000 have been tested worldwide. The likelihood of prove Down’s syndrome is more than 99%, a little lower than the other trisomies. The risks of false positive tests are very low, however if the test should prove sign of chromosome diseases we advise tests of the amniotic fluid and the placenta. 15 The test is offered pregnant women who: wish a screen of the above-mentioned chromosome diseases without any risk of provoke miscarry (also in cases of pregnancies with twins) has increased risk of chromosome diseases after double test and nuchal translucency scan has been through IVF treatment has an increased risk because of their age has increased risk of miscarry, infectious liver inflammation or HIV (AIDS) Response will be in two-three weeks. Emotional strain Going through fertility treatment can often be an emotional strain. Questions and concerns will pop up, and you might both feel hope and disappointment. To be well informed can be a great help to prevent too many concerns and questions. Moreover, it helps to discuss and talk about your feelings during the treatment. It is important to be positive and optimistic, however also realistic. We will do out utmost to support and guide you. If you feel too concerned or have issues, which are hard to overcome please be aware that we have a psychology connected to Ciconia and you can book a consultation. If you have any practical problems please feel free to contact Ciconia directly. Complications, side effects, and risks Hormone treatment - common side effects It is not unusual that you get tired and will experience mood swings during a treatment with hormones. The injections may cause local irritation, redness, and soreness around the injection site. Always read the patient information leaflet carefully. Cancelling of treatment before the insemination The treatment may be cancelled before the insemination if there are too many follicles, ovarian cysts or the man or woman contract a disease. Too many follicles Some patients unexpectedly react very strongly to the hormone stimulation and will produce more follicles than expected. We will of course try to take this into consideration when planning the treatment, but in some cases it may be necessary to stop the treatment and start over with a smaller dosage next time. Hormone treatment and ovarian cancer Some women are unfortunately born with dysfunctional ovaries. This means that they are at a greater risk of childlessness as well as ovarian cancer. However, a worldwide study has shown that women who have received hormone treatment are not at an increased risk of ovarian cancer. 16 Twin Pregnancy Naturally, the chance of twin pregnancy is higher when insemination is performed with two follicles. Twin pregnancies are not always without complications and therefore you must be monitored closely. E.g. the risk of premature birth is increased. Please make sure to notify us, if you wish to avoid the increased risk of twin pregnancy. If so, we will only inseminate with one follicle and maybe omit hormone stimulation. In rare cases two follicles may cause a triplet pregnancy because a single egg is able to split into twins after the fertilization Expenses for the IUI treatment The price for an IUI treatment includes all scans during the treatment cycle, until a pregnancy test is done approximately 14 days after, as well as a ultrasound scan in case pregnance us achieved. Acupuncture and donor sperm are not included in the overall price. These services are paid separately when you visit the clinic. On the day of the insemination you will receive an invoice for the treatment and any additional service. It is possible to pay either in cash, via home banking, or credit card. However we do not accept foreign cards. Medical expenses The medical expenses for the IUI treatment are very limited. Most people can do with a tablet treatment and a single ovulating injection. If it might be necessary with more than one injection with the follicle-stimulating hormone (FSH), we will apply for a so-called “reimbursement for the chronically ill”. This entails that medical expenses within a year will not exceed DKK 3,800. If you are a member of “Sygeforsikringen Danmark” you will receive a contribution to the medication. The contribution depends on which group you are a member of. When the treatment is initiated we will send the pharmacy a prescription for the majority of the medication, which is required during the treatment. If during the treatment it is necessary with more medication, we will write an additional prescription or exceptionally provide you with medication from the supply at CICONIA. THe pharmacy will bill the medication from CICONIA. Future If you experience several unsuccessful attempts of insemination we will guide you through this difficult phase. In future in vitro fertilisation (IVF) treatment can be a new possibility for you to become biological parents, and we will provide you with all necessary information. The National Association for the Involuntary Childless In 1990 the “The National Association for the Involuntary Childless” was founded. Do you wish to establish contact with other couples in the same situation as yours, you can call the The National Association for the Involuntary Childless at +45 3529 4257. The Association publishes the magazine, “KIMEN” and work actively to improve the treatment possibilities of childlessness. 17 Medication and side effects Different types of medication in connection with treatment at the clinic: Type of medication Effect Examples of the most common side effects Pergotime Stimulates the ovaries and causes the biggest follicles to grow and mature the eggs. (Most frequently used in connection with IVF treatment.) Temporary heat sensitivity, nausea, blurred vision, and headache. FSH f.eks Puregon Gonal-F Menopur Pergoveris Hormonal drug that stimulates the ovaries and causes more than one egg each menstrual cycle to mature. Is given as an injection through the skin just below the navel. (Most frequently used in connection with IVF treatment.) Local soreness around the injection site. Hot flushes and sweat. Ovitrelle Matures the eggs at the final stage and causes ovulation. Is given as an injection when the follicles have reached a satisfying size. Headaches, tiredness, and Ovarian Hyperstimulation Syndrome Viagra Viagra is used to treat erectile dysfunction (impotence) in men. Blushing and headache. 18
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