LABOUR AND MANAGEMENT IN RECONSTRUCTION H E L ab o u r P a r ty h as show n b o th im agination an d vision in th e interim rep o rt on reconstruction problem s in w ar-tim e issued early in M arch u nder th e title “T he Old W orld a n d th e New Society” * for dis cussion a t a series of regional conferences an d a t th e an n u a l conference of th e L abour P a r ty being held a t W hitsuntido. I t seems to have grasped th e relation o f reco n stru ctio n to th e w ar effort a n d p u ts th e p o in t as forcibly as it has been p u t b y Sir Stafford Cripps, a n d in a b rillian t in tro d u c to ry n o te to a recent P E P b ro ad sh eet on bodies in G reat B rita in considering reco n stru ctio n problem s. I n d etail an d in broad outlook, th e rep o rt is evidence th a t th e L abour P a rty is facing u p to th e problem s of th e post-w ar world, a n d th e whole sp irit o f th e rep o rt justifies th e hope th a t a n a tta c k on th e problem s of post-w ar recon stru c tio n m ay be possible on n o n -p arty lines. A ny such p ro sp ect is sure of th e atte n tio n of scientific w orkers if only for th e w ider possibilities it w ould offer o f utilizing th e ir services in th e solution o f such problem s a n d th e estab lish m en t of th e four freedom s. T heir in te re st in th e p resen t rep o rt is alread y claim ed b y its reference to th e im portance of research an d to th e need for a m ore creative a ttitu d e on th e p a r t b o th of G overnm ent an d of in d u stry to science an d scientific research. The rep o rt calls for th e conscious a n d d eliberate endow m e n t of scientific research, b o th p u re an d applied, th e financial responsibility for w hich shall be shared b y in d u stry an d th e S tate. T here is no field of economic life in w hich th e possibilities of scientific ad vance are n o t im m ense. M any of th em are arrested or w ith h eld from en joym ent b y th e m otives in h eren t in a profit-m aking society, an d while it m ay ta k e tim e to lib erate such po ten tialities from th e p resen t restrictin g forces, th e necessary endow m ent o f scientific research should n o t be jeopardized. I n th e sam e vein, th e rep o rt directs a tte n tio n to th e need to ap p ly in th e w ork of reco n stru ctio n some o f th e im p o rta n t lessons of m anag em en t an d in d u s tria l w elfare th a t h av e been learned or reinforced during th e W ar. T he w idespread failure to apply th e know ledge acquired by th e In d u strial H ealth R esearch B oard a n d its predecessor tw en ty or more years ago has been profoundly discouraging to m any scientific w orkers. T heir su p p o rt should be assured for a n y m ove to secure th e fuller u tilization o f th e experience w hich is now being accum ulated on such m a tte rs as com m unal feeding in factories, th e organi zation of m edical inspection a n d care as a norm al fu nction o f m anagem ent, th e evolution of factory discipline b ased on consultation a n d co-operation ra th e r th a n on coercion, th e full use of industrial psychology in te stin g fitness for th e job, th e selection for executive posts in term s o f te ste d com petence and th e p ro p er plan n in g of facto ry accom m odation. T h e im p o rtan ce of wise m anagem ent, utilizing th e scientific techniques w hich are now a t its disposal els T C O N T E N T S Labour and^Management in Reconstruction Speculations in Immunology. . . By Prof. A. A. Miles Page 559 562 Logical Foundations of JPsycho-analysis. By Dr. John Cohen . . . . . . . . 563 Materials and Structures . . 563 W o rk of Pierre Duhem. By Dr. H. Jeffreys, F.R.S. 564 Mainly on W ild Geese. . . . . . 564 Radioactivity and the Completion of the Periodic System. By Prof. F. A. Paneth . . . . By Seton Gordon, C.B.E. 565 Mosquito-breeding in Static W a te r Supplies. By J. F. Marshall, C .B.E............................................................568 Science and W a r. By Austin H. Clark . 570 Statistical Control of Production. By Dr. C. G. Darwin, F.R.S............................................................................ 573 Obituary : Mr. W . P. Pycraft. By Sir A rthu r Smith Woodward, F.R. S News and Views . . . . . . . 575 576 Letters to the Editors : Cosmic Rays Duperier and Magnetic Storms.— Dr. . . . . . . . A. 579 Dispersion of Cellulose Strands in Cell Walls.— Dr. R. D. Preston . . . . . 580 Effect of Certain Chemotherapeutic Agents on Experimental Eye Lesions produced by Staphylo coccus aureus.— Dr. J. M. Robson and Major G . I Scott . . . . . . . 581 Microbial Synthesis and Autolysis in the Digestive Tract of Herbivora.— Frank Baker. . . 582 Spore Dispersal in the Mucorales.— Dr. C. G. Dobbs .......................................................583 Sea Waves : Their Growth and Subsidence. By P. J. H. U n n a .........................................................................584 New Seismograph Station at Logan, Utah 585 Editorial and Publishing Offices M ACM ILLAN & CO., LTD., ST. M A R T IN ’S STREET, L O N D O N , W .C .2. Telephone N um ber: Whitehall 8831 Telegrams: Phusis Lesquare London A dvertisem ents sh o u ld b e a d d resse d to T . G . S c o c t & S o n , L td ., T h r e e G a b le s, L o n d o n R o a d , M e rs th a m , S u r re y T e le p h o n e : M e rsth am 316 T h e a n n u a l s u b s c r ip tio n r a t e is £4 10 0 , p a y ab le in a d v a n c e . In lan d o r A b ro a d All r ig h ts re s e r v e d . R e g is te re d as a N e w s p a p e r a t t h e G e n e r a l P o s t O ffice * T h e O ld W a r a n d th e N ew S o c ie ty : a R e p o r t o n th e P ro b le m s o* W a r a n d P e a c e R e c o n s tr u c tio n . P p . 32. (L o n d o n : T h e L a b o u r P a r t y , 194 2 .) 3d. 560 N A T U R E M ay 23, 1942, v o l. 149 th e program m e outlined b y Mr. C ourtauld an d by well as th e increasing store of factu al know ledge as a basis for policy a n d decisions, in reconstruction as th e L ab o u r P a r ty ’s rep o rt, an d also b y Prof. C arr in well as in fu rthering th e w ar effort, is n o t easily ov er h is ch ap ter on “B ritain a t H om e” in his recen t book, stressed. I t is one indispensable facto r in rem oving “ Conditions of P eace” . Mr. C ourtauld believes th a t friction an d m isunderstanding betw een m anagem ent th e tim e is ripe for a review of th e principles and an d w orker an d developing th e sp irit an d practice of bases of in d u stry , an d he points to th e acceptance b y in d u strialists to -d ay of th e inevitableness of co-operation upon w hich efficiency depends. T he change, to th e ir conscious respect for B ritish ideals seventh a n d eighth rep o rts of th e Select C om m ittee o n N atio nal E x p en d itu re afford sufficient evidence an d th e progressive gains of th e p a s t in w hich all classes have h a d a h an d . T here is also a re-aw aken on th is p oint, a n d th e y show also th a t co-operation ing of conscience : an in d u strial career is now a involves a contribution from th e w orkers them selves. A new outlook a n d an u nprejudiced a n d forw ard- metier, n o t m erely a ro ad to p riv ate acquisition. looking m ind are dem anded of labour as well as of F o u rth ly , he notes a grow th of real fellow-feeling m anagem ent in order th a t th e natio n al effort for w ith th e lower ran k s of in d u stry , who h av e come to share th e sensibilities an d aspirations of those placed w inning th e w ar a n d building th e peace m ay a tta in above them . its full pow er a n d efficiency. F o r all th is, th e leaders of in d u stry are n o t likely to T he hope th a t full co-operation betw een m an ag e m e n t a n d labour m a y y e t be achieved an d th a t b e stam p ed ed in to throw ing every th in g overboard, th e problem s o f post-w ar reconstruction m ay be for th e y h av e a firm faith in m an y enduring principles w ith o u t w hich th e re is no possibility of sound rebuild approached u ntram m elled b y th e prejudices of p a rty politics is encouraged b y th e views expressed alm ost ing. T here are m an y passages in th e L abour P a r ty ’s sum ultaneously b y Mr. B evin an d Mr. Sam uel re p o rt w hich in d icate a t least some appreciation of C ourtauld. R eferring p articu la rly to problem s of th is position, an d it w ould b e tru e to say th a t m ost, if n o t all, of Mr. C ourtauld’s assum ptions are im plicit dem obilization afte r th e W ar, Mr. B evin stressed th e im portance of closer co-operation betw een w orkers in its own argum ent. Mr. C ourtauld assum es, for exam ple, th a t p ro duction is th e m ost v ita l activ ity an d em ployers an d th e inevitability of greater S tate control. T he fa ta l error w ould be to allow th e desire of th e n atio n an d th a t G overnm ent control has come to stay . N o G overnm ent, he says, can to lerate the for quick profits or th e disposition tow ards rap id an d u ndue expansion to d isto rt post-w ar developm ent existence w ith in its borders of an organized and com pletely indep en d en t pow er w ith a radius of action in to a disastrous boom . T he controls w hich have apportioned resources in w ar econom y m u st be m a in as w ide as its own, a n d th e sam e overriding principle tain ed in order to d istrib u te those resources in th e th a t m akes it th e d u ty of th e G overnm ent to control m ost beneficial m anner afte r th e W ar ends. T here in d u strial com bination applies to tra d e unions as developed to -d ay . G overnm ent bureaucracy, he m u st be a g rea t n atio n al discipline as keen an d efficiently im posed as th a t w hich has grow n u p during holds, as it exists in G reat B ritain , has proved itself hostilities, u n til th e problem s of re-settlem en t have incapable of conducting business efficiently ; it would require d rastic reform to enable it to ta k e an y p a rt been w orked out. Clearly Mr. B evin is prep ared to face th e u n p o p u in th e ru n n in g of business. Mr. C ourtauld assum es th a t labour will increasingly la rity w hich m ay accom pany th e a tte m p t to guide th e n atio n along a difficult p a th w hich prom ises share in th e m anagem ent policy an d rew ards of p erm an en t recovery ra th e r th a n a te m p o rary boom . in d u stry an d th a t th e tra d e unions will long continue The tw itterin g s w hich Sir W illiam B everidge’s stim u to rep resen t labour. G am bling in in d u strial counters latin g article in T he T im es has caused in th e stro n g is a m alig n an t disease for in d u stry itself. The holds of individualism a n d laissez-faire are tok en of E nglish genius for social evolution a n d for compromise can find a m iddle w ay betw een p u re individualism th e opposition th a t will be forthcom ing from th e rec alc itran t a n d backw ard-looking m in o rity w ho find an d p u re socialism w hich will bring th e greatest th e ir p riv ate interests th reaten ed . Mr. Samuel a tta in a b le good to th e n atio n an d leave m ore and C ou rtau ld’s article in th e Economic Journal of A pril m ore v ested in terests o u t in th e cold. Furtherm ore, he draw s a d istin ctio n betw een productive industry shows, how ever, th a t th e re are leaders in in d u stry as in science who are facing th e fu tu re w ith u n p re a n d financial in stitu tio n s w hich m an y scientific w orkers have voiced before, an d his views on ad v er judiced an d receptive m inds. Mr. C ourtauld’s article m akes p articu larly in te r tising an d p a te n t law as well as on financial in stitu esting reading in th e light of th e L abour P a r ty ’s tions are tolerably certain to be th e su b ject of lively debate. rep o rt. M uch of th e ground covered is com mon, W e m ig h t well hope th a t these fu n dam ental though th e L abour P a r ty ’s rep o rt includes colonial an d in ternational affairs in its survey. Mr. C our assum ptions are sufficiently sh ared b y th e labour side of in d u stry to induce a com m on appro ach to th e ta u ld , on th e other han d , sta te s th e questions ra th e r th a n gives th e answers, a n d if he seems te n ta tiv e , he b ro ad questions bearing on th e relations of G overn is free from th e flavour of dogm atism w hich a t tim es m e n t an d in d u stry which Mr. C ourtauld p u ts w ithout alw ays suggesting an answ er. F ix ed policy an d the creeps in to th e L abour P a r ty ’s report. W hen we have reached agreem ent as to th e ques choice betw een free tra d e a n d p rotection, w ith th e tions to be asked, we are en titled to expect some allied question of subsidies ; G overnm ent ownership m easure of co-operation in th e search for th e answers, a n d control an d th e m eth o d of exercising control, an d th ere is a striking resem blance in th is respect in w ith th e relatio n betw een in d u strial representation No. 3786, M ay 23, 1942 NATURE an d th e G overnm ent ; th e rig h ts of labour, w ith such allied questions as th e ir voice in control an d m anage m ent, fam ily allowances, security an d wages ; in d u s tria l planning, b o th geographical an d h um an, including technical e d u c a tio n ; th e protection of consum ers ; an d th e control o f speculation—these are all b ro ad questions on w hich it ia for th e nation, an d n o t in d u stry itself, to indicate in advance th e m ain lines of th e policies concerned. On all these topics Mr. C ourtauld offers p ertin en t com m ents a n d suggestions, as well as on th e highly technical questions, sim ilarly calling for a n ational lead in policy, such as th e ta x a tio n o f in d u stry , lim itation o f profits, depreciation a n d research ex p en d iture ; equalization of rates ; p a te n t law ; a n d w hether selling an d d istrib u tio n cost too m uch to-day. I t is tru e th a t on certain points he is som e w h at nebulous. H o recognizes th e im portance of retai ning th e p riv ate initiative w hich fosters economic progress, an d a t th e sam e tim e wishes to m ake G overnm ent control in th e interests of th e com m u n ity effective. T he solution he offers, nam ely, th e ap p o in tm en t of G overnm ent directors, is nevertheless scarcely adequate. The key problem of post-w ar economic policy is, how ever, fairly raisod. In d u stria l m anagem ent m u st be efficien t; th is ca n n o t be achieved b y Civil Service formulae, an d th ere m u st be com m unal control. The solution m ay well lie first in th e train in g an d evolu tio n of a new ty p e of Civil S ervant com petent in in d u strial an d economic affairs, an d second, an d m ore im p o rta n t, as Mr. Geoffrey Crow ther insists, in draw ing a sharp distinction betw een those essential industries, such as food, tra n sp o rt, an d p robably fuel, w hich m u st be m anaged directly u nder th e eye of th e com m unity, an d those w hich m u st be p erm itted to develop w ithin th e usual p a tte rn of p riv ate e n te r prise b u t also w ithin th e p a tte rn of a decent, civilized an d dem ocratic society. Mr. C ourtauld’s article is stim ulating an d refresh ingly free from prejudice. H is observations on th e p lanning of th e hum an side of in d u stry as well as its geographical aspects are welcome, a n d it is encour aging to find an in d u strial leader openly expressing th e opinion th a t no business should be allow ed to em ploy m ore juveniles th a n it can absorb la te r into th e ran k s of full-grow n w orkers. T he elim ination of blind-alley occupations is a ta sk th a t calls im p e ra tively for th e closer co-operation o f G overnm ent, em ployers an d labour. I t is a m a tte r on w hich scientific w orkers m ay well be expected to m ake th e ir own co ntribution, an d Mr. C ourtauld’s observation th a t care should be ta k e n n o t to educate people into blind alleys is one th a t teachers, too, should note. T he com m ent th a t colleges an d technical schools pay insufficient atte n tio n to th e ir responsibility for relating th e num ber of pupils ta u g h t to th e probable d em and for th em is fair, if it is tru e th a t q u a n tita tiv e train in g an d recruitm ent im ply willingness on th e p a rt of th e em ployer to forecast an d estim ate his requirem ents. B y an d large, m uch of Mr. C ourtauld’s article finds its co u n terp art in th e L abour P a r ty ’s rep o rt. R ecog nition o f th e inability o f an unplanned society to 561 m a in tain a reasonable sta n d ard of life for m any of its citizens is com m on ground, as are th e consequonces th a t flow from un reg u lated p riv ate enterprise— th e restrictio n o f production, w aste of skilled man-pow er a n d failure to use th e achievem ents o f science an d technology to raise th e sta n d ard of life. Im p licit in b o th Mr. C o u rtau ld ’s p ap e r an d th e L abour P a rty re p o rt is th e acceptance of th e objectives sta te d by P resid en t R oosevelt a n d of th e establishm ent of th e fo u r freedom s ; indeed, th e whole o f th e L abour P a r ty ’s rep o rt shows th a t th e p a rty has grasped th e tr u th s o utlined so ab ly b y Prof. C arr in “ Conditions of P eace” , a n d th a t it recognizes th e stren g th which a reco n stru ctiv e policy will lend to th e w ar effort. D em ocracy can n o t develop its full pow er in w inning th e W ar unless we begin during its course to organize th e conditions w hich will ensure th a t w hen victo ry is w on th e g reat ends of life will be effectively served for every citizen. T he rig h t n o te of cau tio n is sounded b o th in th is rep o rt an d in Mr. C o u rtau ld ’s address. T he first aim is to w in th e W ar, an d a n y m easures now adopted m u st be justified first b y th e ir co n trib u tio n to v icto ry . A t th e sam e tim e, unless opportunities th a t now p resen t them selves of destroying rath e r th a n consolidating abuses an d ob stru ctio n s are used, it is useless to ta lk of rebuilding in d u stry or society on b e tte r foundations. W hile, how ever, th e re is m uch indeed in th e report th a t indicates th a t th e L abour P a rty is prep ared to face questions of in d u strial organization an d th e like in a new sp irit a n d w ith an open m ind, one grave defect m a rs th e rep o rt. I t is com m on ground in alm ost ev ery im p a rtial analysis of th e new society th a t is to be established afte r th e W ar th a t stab ility will d epend on stress being laid on obligations rath e r th a n on rig h ts, on services rendered to th e com m unity ra th e r th a n on benefits to b e draw n from it. A social order in w hich th e four freedom s of President R oosevelt are to b e em bodied in a social m inim um for every citizen m u st h av e as its co u n terp art a sta n d a rd of du ties an d obligations w hich are expected of all. I t is th is n o te th a t is lacking in an otherw ise ad m ir able s ta te m e n t. N o u n ite d a tta c k on th e problem s o f p ost-w ar reconstruction, no n o n -p arty approach is possible in its absence. I f th e em phasis falls exclu sively on benefits a n d rig h ts, no dem ocratic order will be established wide enough to resist th e renewed o n slau g h t of a u th o rita ria n regim es w hen th e present aggressors h av e been overthrow n. The essential ta sk is to tra n sm u te in to th e service o f peace an d th e building of a new order o f society, th a t sp irit of com radeship, o f unselfish a n d strenuous endeavour th a t th e v ery p reservation of dem ocracy now dem ands. I f in th e discussions th a t ensue on th e basis of th is rep o rt th is n o te of service an d d u ty is firm ly sounded, as th e open-m indedness of th e rep o rt w arra n ts th e hope, it should n o t b e vain to look fu rth e r for th a t u n ite d a tta c k on th e problem s ahead o f us, free from prejudice an d p a rty restrictions, in w hich th e resources an d skill of scientific w orkers am ong others can be fully an d effectively deployed, to th e lasting benefit of m ankind. 562 NA T U R E SPECULATIONS IN IMMUNOLOGY M ay 23, 1942, V ol. 149 As an altern ativ e, D r. B u rn et in th e first place p ostu lates th a t th e serum globulins are products of The Production of Antibodies self-reproducing intracellular proteinases, an d repre A Review an d a Theoretical Discussion. B y D r. sen t a stage in th e synthesis a t w hich th e molecule F . M. B u rn et, w ith th e collaboration of M avis F re e has th e essential stru c tu re of th e enzym e itself, and m an, A. V. Jackson, D ora L ush. (M onographs from is consequently stable. In th is form it is presum ably th e W alter and E liza H all In s titu te of R esearch in tu rn e d o u t in th e circulation ; in th e cell, th e pro P athology an d Medicine, M elbourne, No. 1.) P p. teinase reproduces itself fully. A sim ilar conception has viii + 76. (M elbourne a n d L ondon : M acm illan and been ad vanced for th e m u ltiplication o f p la n t viruses, Co., L td ., 1941.) 8s. 6d. net. b u t th e re is no v alid reason w hy it should n o t apply H E introduction o f com plex foreign substances to syntheses in norm al cells. In th e n ex t place, it is o f high m olecular w eight into th e tissues of p o stu lated th a t these proteinases, in v irtu e of their w arm -blooded anim als often leads to th e appearance enzym ic function, come in to co n tac t w ith any of antibodies in th e blood serum . T he reaction of foreign antigens ta k e n in to th e cell, an d are lastingly these antibodies w ith th e substance th a t stim u la ted modified b y th is co n tact. T here is no synthesis of a th eir appearance— th e antigen—is largely specific. new u n it in sp a tia l co n tac t w ith th e an tigen (the Im m unologists have in th e m ain confined th e ir ‘te m p la te ’ view) b u t a change in th e ato m ic stru ctu re atten tio n to th e specificity of com bination betw een of th e p roteinase th a t allows its effectively hydrolytic antigen an d corresponding antibody. A nalysis of action on th e foreign antigen. W hen th e antigenic n atu ral antigens an d th e artificial m odification of stim ulus is rem oved, th e m odified p roteinase con protein antigens b y th e addition of activ e chem ical tin u es to synthesize itself, b o th in th e original cell groups to th e surface of th e molecule have bo th an d its descendants, b u t th e re is a slow reversion to proved fru itfu l in revealing w h at p a rtic u la r con th e original ty p e, a n d th e a n tib o d y grad u ally dis figurations in th e antigenic p article determ ine its appears from th e circulation. A second injection of power to induce an d to com bine w ith specific a n ti th e antigen is followed b y a rap id h y d ro ly tic action body. M uch less is know n a b o u t th e origin and by th e specifically m odified proteinase, w hich yields stru ctu re of antibodies them selves. A single injection prod u cts o f p a rtia l hydrolysis th a t in tu rn m odify the of antigen som etim es yields a detectable a m o u n t of proteinase fu rth er, a n d so lead to progressive change antibody, b u t its m ost striking effect is to sensitize in th e n a tu re of th e an tib o d y . th e anim al in such a w ay th a t a subsequent injection Speculative hypotheses of th is k in d serve two induces a ra p id an d disproportionately large o u tp u t useful purposes. T h ey m ay direct a tte n tio n to the o f an tib o d y . U pon th e readiness of th is ‘secondary facts th e y p u rp o rt to co-ordinate, an d th e y m ay link response’ depends th e persistence of im m unity in u p th e field of speculation w ith h ith e rto unrelated m an an d anim als ; th o u g h all d etectable p rotective fields of science. D r. B u rn e t’s speculations serve the an tib o d y has disappeared, th e an tib o d y response of second purpose less hap p ily th a n th e first. As an th e conditioned anim al to la te r co n tact w ith antigen exam ple, we m ay consider th e m odification of th e is im m ediate an d effective. self-reproducing proteinase b y th e antigen. W e m ay A ntibodies are m odified serum globulins, a n d it assum e th a t th e p roteinase exists, an d th a t globulin appears th a t an tib o d y globulin is produced in th e is n o t form ed b y a m ore com plex sy n th etic u n it cells of th e reticulo-endothelial system , an d perhaps w hich is in effect self-reproducing. B u t th e ju stifi cation for th e ty p e of m odification p o stu lated rests in lym phoid tissue. I n th e absence of an antigenic stim ulus these cells presum ably synthesize th e norm al on d oubtful analogies w ith ad ap tiv e enzymes, an d globulins. W e have little know ledge of th e origin of w ith th e train in g of a b acterial culture to utilize th e norm al serum proteins, an d are consequently substances th a t are n o t norm al p articip a n ts in its unable to speculate very profitably a b o u t th a t of th e m etabolism . T he ad a p tiv e enzym e, th a t becomes modified an tibody globulin. T he c u rren t hypothesis evid en t w hen b ac te ria l cells are b ro u g h t in to contact is an extension of F ischer’s lock-and-key analogy for w ith its corresponding su b strate, bears a superficial th e specificity of com bination betw een an enzym e resem blance to an tib o d y in th a t it is specifically an d its su b strate. I t supposes th a t th e am ino acids called in to being b y th e su bstance on w hich it acts, destined for synthesis in to globulin are specially b u t th e re is little evidence to su p p o rt D r. B u rn et’s disposed in a cell containing antig en ; th e y are held suggestion th a t it represents a m odification of an in a p a tte rn determ ined by th e n a tu re and arran g e existing co n stitu tiv e enzym e. So fa r as is know n, a m en t of th e active groups on th e surface of th e b acterial species possesses a finite range of ad ap tiv e enzymes, an d th o u g h peculiar conditions are required antigenic particle, an d in th is p a tte rn are incorporated for th e ir synthesis, th e y characterize th e species as in to th e globulin molecule, w hich th u s bears th e surely as th e co n stitu tiv e enzymes. specific im press of th e antigen. D r. B u rn et rejects th is view of th e antigen as a T he analogy w ith tra in e d b ac te ria is even more rem ote. W e are dealing here w ith an ad a p ta tio n ‘te m p la te’ for antibody production. N o t only does th a t in m a n y cases m ay fairly be considered as th e th e ty p e o f an tib o d y induced b y a single antigen change as im m unization of th e anim al is prolonged, resto ratio n of sy n th etic pow ers lo st in th e evolution o f a b acterial species from an au to tro p h to a heterob u t also th e anim al m ay still synthesize antibody w hen i t is reasonable to suppose th a t th e injected tro p h , an d n o t a calling fo rth of a new an d abnorm al antigen has been destroyed an d th e cells originally activ ity , for th e re is am ple evidence to suggest th a t stim u lated b y it have been replaced b y th e ir m ore or hetero tro p h s m ay re ta in sy n th etic powers w hich are n o t ord in arily m anifest because th e y are q u an ti less rem ote descendants. Moreover, th e ‘secondary response’ is often characterized b y a sharp ex ta tiv e ly insufficient for th e full needs of th e organism. p o n en tial rise in th e curve of an tib o d y production, The review is wide, an d includes original w ork by w hich suggests a proliferation of th e antibodyth e a u th o r a n d his colleagues, p articu larly on th e form ing m echanism , ra th e r th a n a rap id ly accelerat form ation of antibodies in lym ph nodes, an d on th e ing production from an already established set of logarithm ic phase of th e secondary response. Dr. B u rn e t’s fondness for th e p u rsu it of rem ote and ‘te m p lates’. T No. 3786, M a y 23, 1942 NATURE sometim es m isleading analogies m ay be overlooked, for his speculations, backed b y th e experim ental facts th a t he has m arshalled, will adm irably serve th e purpose of challenging im m unologists to explain those aspects of a n tib o d y form ation th a t are in adeq u ately covered b y c u rren t hypotheses. A. A. M i l e s . LOGICAL FOUNDATIONS OF PSYCHO-ANALYSIS Psychoanalytical Method and the Doctrine of Freud B y D r. R oland D albiez. Vol. 1 : E xposition. T ra n s lated from th e F rench b y T. F . L indsay. P p . xvi + 415. Vol. 2 : D iscussion. T ran slated from th e F rench b y T. F . L indsay. P p . xii + 331. (London, New Y ork an d T oronto : Longm ans, Green an d Co., L td ., 1941.) 40s. net. T is fitting th a t a critical survey of F re u d ’s w ritings should appear a t th is tim e. In siste n t questions are provoked b y th e W ar. W e w itness th e spectacle of a civilized people reduced to b arbarism w ithin a few years an d w onder how th is is possible. A re wars, it is often asked, sim ply th e outcom e of u n conscious aggressive im pulses ? H ow deep is th e im press th a t civilized living m akes upon th e psyche ? A re hum ane dispositions w holly p a r t of ontogenesis, an d can no such dispositions be tra n sm itte d genetic ally ? To w h a t e x te n t can re-education in th e p o st w ar w orld nullify th e effects of to ta lita ria n p ro p a gan d a instilled during th e im pressionable years of y o u th , an d w h at are th e lim its of v ariatio n in conduct th a t th e sam e individuals m ay express u nder diverse conditions ? No satisfactory answ er to these an d oth er u rg en t questions can be a tte m p te d w ith o u t enlisting th e aid of psycho-analysis. Indeed, it is pro b ab ly tru e to say th a t w ith o u t psycho-analysis, contem porary social behaviour is unintelligible an d no coherent p icture of h um an failings an d aspirations in th e m odern w orld can be draw n w ith o u t invoking its theories, provisional though th e y m ay be. The foundations of psycho-analysis still lie in the w ritings of F reud. T he read er of D r. D albiez’s w ork should therefore be led to th e conclusion th a t th e ta sk of disentangling F re u d ’s analytic technique from th e theory w ith w hich it is interw oven an d of subjecting b o th technique an d th eo ry to close exam ination were well w orth undertaking, an d th a t D r. D albiez has ac q u itted him self w ith rare com petence. H e brings to psycho-analysis a sta n d a rd of logical d em o n stra tion th a t has long been painfully lacking in th is field. Several chapters, p articu la rly th e one en title d “T he Various N euroses” , are notew orthy for th e ir qualities of lucid exposition. A specially useful contribution is th e system atic a tte m p t to relate th e w ork of F re u d to th a t of Pavlov. This effort to unify tw o independent h y p o theses form ulated in very different term s m eets w ith a large m easure of success. E v en th e m uch-disputed CEdipus conflict is readily tra n sla te d into th e language of reflexology, an d is show n to resu lt from a clash betw een th e processes of excitation an d inhibition, th e genital reflex m echanism s failing to differentiate betw een tw o sim ilar stim uli. D r. D albiez m aintains th a t th e developm ent of th e sexual im pulse reveals itself in a progressive differentiation of object. This view is presented as m ore in accordance w ith th e facts th a n is th e F reu d ian notion of sexual develop m en t as a succession of perverse phases culm inating I 563 in norm al heterosexuality. The belief th a t sexual developm ent proceeds b y in teg ratio n of separate responses is in line w ith recent experim ents on aggressive im pulses in certain anim al species. M ention should be m ade of th e discussion on sym bolism, w hich clears u p m an y confusions in th e litera tu re. In p articu lar, th e retrospective, reductive, causal in te rp re tatio n of sym bolism w hich is ado p ted by F re u d is co n trasted w ith th e prospective, synthetic, teleological view of Silberer. A n u m b er of criticism s rise to m ind. T he size of th e second volum e could h av e been m uch reduced ; its m a tte r is scarcely com m ensurate w ith its bulk. One m ay blam e th e philosophic train in g of th e au th o r for a n u m b er of pu rely academ ic discussions. The ch ap ter dealing w ith th e psychoses in th e first volume can scarcely be regarded as having achieved its aim. A b o u t a th ird of th is ch ap ter is devoted to a criticism of D r. de C leram bault’s theories of m en tal au to m atism , an allocation of space w hich is surely u n m erited. I t is disappointing to find th a t aggressive behaviour is n o t accorded due recognition. The word ‘aggression’ does n o t even ap p ear in th e index. The w orld of D r. D albiez seems to be th e peaceful world of th e philosopher, an d one w ould g ath er th a t F reu d a tta c h e d little or no im portance to aggressive im pulses— a deduction w hich w ould be v ery misleading. J o h n Co h en . MATERIALS AND STRUCTURES Materials and Structures B y D. A. R . Clark. P p . xii + 384. (London, Glasgow an d B om bay : Blackie a n d Son, L td ., 1941.) 25s. net. Practical Design of Simple Steel Structures B y D r. D avid S. S tew art. Vol. 1 : Shop P ractice, R iv eted Connections an d Beam s, etc. ; a T ext-B ook suitable for Civil Engineers, S tru c tu ral Engineers, R o a d an d R ailw ay Engineers, an d S tudents a t U niversities a n d Technical Colleges. Second revised an d enlarged edition. Pp. xv+ 184. (L ondon: Constable an d Co., L td ., 1941.) 14s. n e tH E first of these tw o books h as been w ritten to m eet th e needs of stu d e n ts prep arin g for exam inations in stren g th of m aterials an d stru ctu res such as those in P a r t I of th e U n iv ersity of London degree, H igher N atio n al Certificate an d engineering in stitu tio n s’ syllabuses. These dem and knowledge of th e calculus, an d th e book assum es a sim ilar standard. I t is therefore disconcerting to find several pages given u p to th e w orking o u t in d etail of th e formulae for th e m om ents of in ertia of such sim ple sections as form th e m ost elem entary exercises in integration. I f th e read er requires to b e show n th e detailed opera tions in th e case of these geom etrical sections, by how m uch th e m ore m u st he need some light on th e m ethods b y w hich p ractical sections can be evaluated. F ro m th is p o in t of view th e a u th o r has n o t gone far enough to satisfy th e needs of stu d en ts a t th e stage indicated. T he p a tte rn of th e book is determ ined b y its d e v o tio n to th e su b ject of stru ctu res, an d this gives it a d istin ct ch aracter. In ste a d of ranging over th e aspects of stren g th of m aterials w hich ap p ertain to m achines, it confines itself to those concerned w ith stru ctu re s an d its exam ples are draw n from this b ran ch of engineering. I t is therefore to th e stru ctu ral engineering stu d e n t in p articu lar th a t it will appeal an d w hom it will m ost g reatly help. H e will find it a valuable m edium of p rep aratio n for his profession T 564- NATURE as well as for tlie m ore im m ediate needs of exam ina tions. Following a v ery able presen tatio n of th e behaviour o f m aterials u nder stress, th e re is a useful chap ter on th e pro d u ction of m etals a n d on th e various tr e a t m en ts b y w hich steel, in p articu la r, can be im proved or developed in certain desired directions. Besides fam iliarizing th e stu d e n t w ith th e m etals, th is will assist h im in u n d erstan d in g th e ir specifications. A len g th y ch a p te r on testin g contains m uch inform ation regarding th e recognized te sts an d test-pieces, an d describes various te stin g m achines an d appliances, th e te x t being supplem ented b y diagram m atic sketches illu stratin g th e ir principles. T he la tte r p a r t of th e book is devoted to stru ctu res, a n d tre a ts of fram ed stru ctu res, influence lines, deflections, sus pension chains an d bridges, a n d finally m asonry. As a concise an d educative sta te m e n t of th e th e o ry of stru ctu res, th is section can be confidently recom m ended to th e stu d e n t to w hom th e sub ject is as y e t unfam iliar. In co n tra st to th e volum e ju s t described, D r. S tew art’s book deals w ith th e practical design of some o f th e m ore sim ple stru c tu ra l details. In its earlier ch apters it provides inform ation regarding th e rolled sections used, draw ing office practice an d procedure in relatio n to estim ates an d tenders, specifications an d th e ordering of m aterial— all extrem ely useful inform ation to th e un in itiated . E q u ally so is th e description of th e tem p late loft, th e w orks an d th e m achines an d processes w hich are to be seen there. T he designs w hich are d ea lt w ith in th is first volum e of th e series are of sim ple riv eted fastenings a n d splices for various purposes an d of beam s. The com plete design of a 20 -ft. span g a n try girder form s th e tail-piece. As com pared w ith th e earlier edition, several new features have been introduced in the form of am endm ents to bring th e te x t into line w ith th e la test specifications, fresh m aterial has been ad d ed , a n d an in novation is m ade in th e arran g e m e n t of th e te x t on th e final design so th a t th e calculations an d ex p lan ato ry notes are k e p t a p a rt on opposite pages, th u s giving a greatly im proved p resen tatio n of th e sub ject in its tw o aspects, in stru ctio n an d exam ple. W O R K OF PIERRE DUHEM The Methodology of Pierre Duhem B y A rm and Lowinger. P p . ix + 1 8 4 . (New Y o rk : Columbia U niversity Press ; L ondon : O xford U n i v ersity P ress, 1941.) 15s. 6d. net. N a p refato ry note th e a u th o r sta te s th a t his aim is to provide a sum m ary in E nglish of th e w ork o f Prof. P ierre D uhem (1861-1916) on scientific m ethodology. T he g rea ter p a r t of th e book consists o f ex tra cts from his papers an d from his book “La T heorie P h ysique” , published in 1900 an d 1914, w ith connecting passages supplied b y th e auth o r. In the la st ch ap ter th e au th o r offers some criticism s. I t is ra th e r difficult to assess th e value of a book published in these conditions. A t th e p resent tim e th e re is little in it th a t is n o t fam iliar to w orkers in th e subject, m an y of w hom will em phatically accept it an d others equally em phatically reject a g reat deal of it ; to th em th e only question will be w hether D uhem an ticip ated w ork th a t has been generally a ttrib u te d to others. I t does n o t ap p e ar to m e th a t he did. H is approach is su b stan tially I May 23, 1942, V o l. 149 th a t of Macli, except th a t he does n o t w holly reject m etaphysics ; he only draw s a line distinguishing it from science. B u t th is distinction involves th e rejection of “m odels” an d explanations from science ; he insists on a b s tra c t form alism . I should say th a t th e la tte r is v ery good if it can be done, b u t before accepting it as a general principle I should like to see th e facts of geophysics represented w ith o u t th e aid of th e m odel th a t we call ‘th e E a r th ’. H e accepts M ach’s view th a t th e whole aim of scientific theories is econom y of sta te m en t. H e agrees th a t we m ake inferences from th em beyond th e original d ata, an d expect th e results to be verified, b u t says th a t this has no logical justification an d is n o t science. I should say, so m uch th e worse for such a narrow logic. T here is no m ention in th e book of K arl P earso n ’s “ G ram m ar o f Science”, published in 1892, w hich does face th is problem ; a n d I consider th a t an y la te r w ork on m ethodology th a t om its reference to th e “G ram m ar” is like one on g rav itatio n th a t om its K ep ler’s laws or one on th e th eo ry of th e com plex variable th a t om its C auchy’s theorem . D uhem ac tu a lly insists a t a m uch la te r stage th a t we m u st accep t testim o n y ; b u t we could n o t even arriv e a t th e m eanings of w ords w ith o u t th e process th a t he has rejected. H. J e f f r e y s . MAINLY ON W ILD GEESE Through the Air A dventures w ith W ild Fowl, an d Sm all-boat Sailing. B y M ichael B ra tb y a n d P e te r S co tt. P p . 128 + 21 plates. (London : Country L ife, L td ., 1941.) 10s. 6(2. net. H IS is a rep rin te d account of a series of b ro ad casts w hich M ichael B ra tb y has m ade, m ainly upon w ild geese, an d th e re are a n um ber of black an d w hite illu stratio n s b y his friend P ete r Scott. T here are also tw o excellent photo g rap h s of a p in k footed goose on her nest, evidently in Iceland or G reenland, an d a m agnificent p h o to g rap h of an A rctic hare. U n fo rtu n ately , we are left in th e d ark as to who took these o u tstan d in g photographs. There are tw o v ery good p h o tographs (facing p p . 57 an d 60), tak en , wo are told, in Icelandic w aters. Ju d g in g from th e icebergs th e clim atic conditions th a t season in Iceland m u st have been exceptionally severe, an d th e conditions recorded resemble, ra th e r, G reenland or Spitsbergen. T here is a m ost in terestin g account (pp. 29, 30) of a flight of blue snow geese descending on th e w ater on m igration in dense m ist an d being sw ept over N iag ara Falls. M ost w ere killed during th a t trem endous descent, b u t a few survived, an d w ere b ro u g h t to E ngland. A nother interesting record (pp. 66 - 68 ) is of a p in k footed goose w hich h ad been sh o t an d slightly ‘w inged’. T his b ird becam e v ery tam e, a m ate was provided for her, an d seven years afte r she was ‘w inged’ th e goose nested in a flower bed in the garden an d reared a fam ily. T here she lived for tw elve years, an d th en , as circum stances h ad altered for h er h u m an friends, she w as given aw ay. She was less h ap p y in h er new surroundings, an d being full winged, joined a skein of wild pink-footed geese, an d was n o t seen again. B y th e w ay, th e a u th o r is w rong w hen he w rites of th e wings of th e lesser black-backed gull (p. 80) as being “as black as coal” . T he wings of th e B ritish lesser black back are soot-grey, b u t th e w ings-of th e S candinavian lesser black back are black. T S E T O N (j O B I) O N . No. 3786, M a y 23, 1942 NATURE RADIOACTIVITY AND THE COMPLETION OF THE PERIODIC SYSTEM* By PROF. F. A. PANETH University of Durham N E of th e trib u te s p aid by th e G overnm ent an d m en of science of th e U .S .S .R . to th e m em ory of Mendeleeff on th e occasion o f th e centenary of his b irth 1 was th e publication o f his “ Collected W orks” . I t contains all th e different tables of th e Periodic System designed by M endeleeff a t various tim es, an d so offers an excellent o p p o rtu n ity to stu d y a t w h a t pace, an d u p to w h at point, th e com pletion of th e system proceeded during his life. In th e first tables, w hich O appeared aro u n d th e y ear 1870, em p ty spaces were left for th e elem ents eka-boron, eka-alum inium an d eka-silicon; for eka-, dwi-, tri-, an d chatur-m anganese; for th e rare e a rth elem ents betw een bariu m an d ta n ta lu m (m any o f w hich were know n b u t could n o t be assigned to definite places) ; for several elem ents betw een b ism uth a n d u ran iu m ; an d , to com plete th e la st horizontal row, for a few tran s-u ran iu m elem ents. T he atom ic w eight of tellurium w as assum ed to be 125, instead of th e experim ental value 128, in order to m ake it sm aller th a n th a t of th e following elem ent iodine, 127. All these sta te m en ts were equivalent to predictions. W hich o f th em did th e au th o r see fulfilled ? In 1886 Mendeleeff him self answ ered th is question in a v ery original w ay. H e h ad four photographic p o rtra its m ounted in a com m on fram e, w ith th e au to g rap hs of th e persons represented an d his own com m entary on th e back. (The second volum e of th e “ Collected W orks” contains a reproduction o f this highly interesting historic piece.) T he four m en an d th e ir contributions to th e developm ent of th e Periodic System , as explained b y Mendeleeff, w ere : Lecoq de B oisbaudran, discoverer in 1875 o f gallium (eka* S u b sta n c e o f a le c tu re d e liv e re d b e fo re th e I n s t i t u t e o f C h e m is try in L o n d o n o n F e b . 18. 565 alum inium ) ; L. F . N ilson, discoverer in 1879 of scandium (eka-boron) ; Cl. W inkler, discoverer in 1886 of germ anium (eka-silicon) ; an d th e Czech chem ist B. B rau n er, who h ad g reatly pleased Mendeleeff by confirming by a re-determ ination of th e atom ic w eight of tellu riu m th a t it actu ally was 125, as expected b y Mendeleeff. W hen in 1905, review ing th e question, Mendeleeff prep ared for th e la st tim e a ta b le of th e Periodic System , scandium , gallium an d germ anium were filling th e low est th ree of th e form erly em p ty spaces, b u t still none o f th e higher homologues of m anganese could be added, an d th e placing o f th e rare earth s h ad m ade b u t little progress ; th e re w ere now indeed tw en ty in stead of n ineteen spaces available betw een b ariu m a n d ta n ta lu m — th a n k s to th e ad d itio n of th e rare gases as G roup 0 o f th e System , th e only really im p o rta n t developm ent betw een 1886 an d MendeWeff’s d ea th in 1907. T he atom ic w eight o f tellu riu m was now assum ed to be equal to th a t of iodine ; M en deleeff a p p a ren tly p ersisten tly refused to believe th a t it was even higher (as proved b y th e best atom ic w eight d eterm inations), alth o u g h B rau n er him self h ad a d m itte d th a t his earlier low value was an ex p erim en tal erro r. T he la st horizontal row shows rad iu m in its p ro p er position a n d so points to a fu tu re developm ent—th e placing o f th e o th er rad io activ e elem ents a n d hence th e conception o f isotopy — w hich Mendeleeff did n o t live to see. I f to -d ay we resum e th e never-ending ta sk of d raftin g a ta b le of th e Periodic System em bodying p resen t know ledge, it will ta k e th e form of F ig. 1, or some ta b le sim ilar to it. W e are now aw are th a t atom ic n u m b er an d n o t atom ic w eight defines th e position of an elem ent, an d th a t betw een barium (atom ic n u m b er 56) an d ta n ta lu m (atom ic num ber 73) th e re are only sixteen places. W e h av e given up hope o f assigning th e fourteen know n rare-earth elem ents to consecutive groups in th e System , an d therefore prefer to w rite th em outside its fram ew ork. The discovery o f hafn iu m (elem ent 72) filled in 1922 th e place o f eka-zirconium ; th a t o f rhenium (elem ent 75) in 1925 th e place of dw i-m anganese. Polonium , radon, actin iu m K , actin iu m , a n d p ro tactin iu m have tak en 566 NATURE th eir respective places in th e la st tw o horizontal rows. O nly throe positions below uranium are left em pty, those corresponding to th e atom ic num bers 43, 61 an d 85, th a t is, eka-m anganese, a rare ea rth , and eka-iodine. Before saying m ore ab o u t these, it seems necessary to ad d a w ord of explanation to th e assign m e n t o f an elem ent actin iu m K to place 87 (ekacffisium). I t is well know n th a t m o st of th e elem ents from th alliu m (81) to u ran iu m (92) are represented b y m ore th a n one atom ic species, th a n k s to th e th ree radioactive disintegration series w hich s ta r t from uranium , actino-uranium , a n d th o riu m an d em it a- as well as (3-particles, th u s covering some p a rts of th e Periodic System rep eated ly (“R adioactive D isplace m en t Law s” ). All th re e series have, how ever, one peculiar featu re in com m on, nam ely, th e successive emission o f four a-particles, sta rtin g from th e thorium isotopes ionium , radio-actinium , a n d radio-thorium , respectively. As a consequence, im m ediately afte r elem ent 90 th e elem ents 88, 86, 84, an d 82 are form ed. T he elem ents 89 an d 83 are nevertheless represented in th e Periodic System , because th e form er is produced in th e actinium an d th o riu m series before, a n d th e la tte r in all th ree series afte r, th e ‘four a-particle r u n ’. E lem ents 87 an d 85, how ever, are m issing in th e th ree disintegration series ; com pare F ig. 2, in w hich th e full line represents th e actinium series in th e generally accepted form . There was alw ays hope o f finding th e m issing elem ents outside th e m ain series as so-called ‘branch p ro d u cts’, an d it was easy to pred ict theoretically, on th e basis o f th e displacem ent laws, w hich atom s would have to undergo a ‘dual d isin teg ratio n ’ in order to produce th e looked-for effect. I f an y one of th e em anations em itted fi-particles (in addition to th e ir well-known a-radiation), or if eith er actinium or its isotope m esothorium 2 em itte d a-particles (in add itio n to th e ir (3-radiation), th e resu lt w ould necessarily be an isotope o f elem ent 87. E x perim ents proved th a t n eith er in th e uranium nor th e th o riu m series does such a branching occur2. On th e o th e r han d , it was found in V ienna3 so early as 1914 th a t carefully purified actinium em itted, in v ery sm all in te n sity com pared w ith th e ac tiv ity of th e m ain series, a-rays of th e range (in air a t n . t . p .) of 3-4 cm . T he possi b ility was considered th a t th is indicated a “ dual disintegration of actinium , a sm all percentage of the atom s em itting a-particles, th e g rea t m a jo rity (3particlea” . T he resu lt o f th e a-radiation would, of M ay 23, 1942, V o l . 149 course, b e th e elem ent 87. T he co n tin u atio n of these researches w as p rev en ted b y th e o u tb rea k of war, b u t th ree years ago Mile M arguerite P erey 4 in P aris n o t only confirm ed th e existence of a-ray s from a c tin ium o f th e range observed in V ienna, b u t also was able to show th a t in purified actinium solutions to a sm all e x te n t a (3-radiating substance of a half-value period of 21 m in u tes is co n stan tly form ed ; th a t this substance can n o t be rem oved b y th e p recip itatio n of sulphides or carbonates, b u t th a t it can be crystallized to g eth er w ith caesium perchlorate o r chloroplatinate. I t seems m ost likely th a t th is (3-radiating substance w ith th e properties of an alkali m etal is th e p ro d u ct o f those co m paratively few actin iu m ato m s which em it a- in stead of (3-particles, an d possesses therefore th e atom ic n u m b er 87. O f 1000 atom s, less th a n 10 seem to follow th is p a th . (In th e disintegration of actin iu m C th e pro p o rtio n is reversed ; ab o u t 2 in 1000 em it fi-particles w hile th e re st decay w ith a-em ission to actin iu m C".) T he (3-radiation displayed b y th is elem en t 87 w ould necessarily lead back to an elem ent 88, p ro b ab ly id en tical w ith actinium X , in th e sam e w ay as b o th ro u tes s ta rtin g from actinium C u n ite in ac tin iu m D . See F ig. 2 ; th e abscissa show s th e atom ic n u m b e r ( th a t is, n u m b er o f protons) o f each atom , th e o rd in ate its m ass n u m b er ( th a t is, n ea rest in teg er to th e ato m ic w eight, or n u m b er of p ro to n s p lu s neu tro n s). F u rth e r confirm ation o f Mile P e re y ’s experim ents is ce rtain ly desirable. T he fac t, however, th a t she w as able to follow th e decay as w ell as th e g ro w th of th e 21-m inutes substance, a n d th e agreem ent o f th e chem ical evidence w ith th e observed a-rad iatio n of actin iu m , is v ery assuring. As th e nam e “ actinium K ” h as been suggested for th is new elem ent we have in serted its sym bol A cK in place 87 o f o u r Periodic T able (Fig. 1). T here is so fa r no tru stw o rth y indication o f a b ran ch in g of a n y o f th e m ain rad io activ e series leading to an elem ent 85, n o r h as a stab le form o f th is elem ent been found. W e m u st assum e a t p resen t th a t th e elem ents 43, 61 a n d 85 are m issing on o u r ea rth . T he reg u larities o f th e P eriodic S ystem enable us to describe ap p ro x im ately th e p ro p erties to be ex pected from th ese elem ents ; b u t especially for 85, since it is on th e b o rd er line betw een m etals an d non-m etals, an d w ith o u t a higher homologue, such pred ictio n s are necessarily vague. F o rtu n a te ly for th e in te rests of chem ists who are sy stem atically m inded, th e re is a possibility of stu d y in g ex p eri m en tally th e pro p erties even o f elem ents w hich are n o t rep resen ted in N a tu re : we can tr y to m ake them , an d if we are lucky enough to o b ta in th em in a (not too short-living) rad io activ e form , th e well-know n m ethods o f rad io chem ical investigation, th a t is, a com bination o f electro m etrical m easurem ents w ith analytical-chem ical operations, will enable us to explore th e ir chem ical b ehaviour even if q u an tities of only 10-10 gm . or less h av e been produced. T he m o st efficient in stru m e n t for atom ic tra n s m u ta tio n is E . O. L aw rence’s cyclotron. O f th e overw helm ing n u m b er of n u clear reactio n s carried o u t w ith its help, for th e purpose of o u r p resen t su rv ey , in w hich we in te n d to om it all d etails of no im m ediate in terest to th e chem ist, we need rem em ber o nly tw o. In m a n y cases w hen an ato m o f atom ic n u m b e r Z and m ass n u m b er M is b om barded w ith d eu tero n s (fD), an ato m o f ato m ic n u m b er Z -f- ] an d m ass num ber M + 1 m akes its ap p earan ce w hile one n e u tro n per ato m is lib erated . I f th e b o m b ard m en t is carried o u t w ith helium nuclei (iH e), an elem ent Z - f 2 of No. 3786, M ay 23, 1942 NATURE 567 in eq u ilibrium q u a n tity , a n d its a-rad iatio n (range 6-5 cm .) decays w ith th e half-value period of its p a re n t, nam ely, 7-5 hours. T h a t m akes it possible to in v estig ate th e chem ical p ro p erties of elem ent 85 as th o u g h i t w ere itse lf em ittin g th e a-ray s. T he final p ro d u c t m u st be th e sam e as th a t o f th e o rdinary AcC', n am ely ac tin iu m D, or ‘actin iu m le ad ’, of ato m ic w eig h t 207. ( I t seems likely th a t th e slime final p ro d u ct is also reached b y an o th e r w ay, as ele m en t 85 a c tu a lly undergoes a d u al disintegration, a b o u t h alf its ato m s em ittin g a-particles.) In Fig. 2 we have in d icated b y d o tte d lines th e w ay in w hich elem ent 85, artificially p roduced from 2g°aBBi, is changing in to th e n a tu ra l radio-elem ent AcC7. This exam ple, w hich is n o t th e first of its kind, illustrates well th a t th e re is no fu n d am e n tal difference between ‘artificial’ an d ‘n a tu ra l’ ra d io a ctiv ity ; it is therefore b e tte r to speak o f ‘artificially p ro d u ced ’, an d n o t of ‘artificial’, radio-elem ents. T h an k s to th e fav o u rab le d ecay p eriod o f more th a n seven h o u rs, th e ch e m istry o f elem en t 85 can be th o ro u g h ly s tu d ie d . T h e follow ing reactio n s are of special in te re s t. M ixed w ith b ism u th it is q u a n tita tiv e ly p re c ip ita te d b y h y d ro g en su lphide in acid solutions. F ra c tio n a l h y d ro ly sis o f b ism u th n itra te enriches elem en t 85 in th e first fra ctio n s ; since it is know n th a t th e ten d en cy o f polonium to hydrolyse is a lre a d y g re a te r th a n th a t o f b ism u th , it w ould be in te re stin g to com pare in th is resp e ct elem ent 85 w ith polonium . Closely connected w ith hydrolysis is th e v ery c h a ra c te ristic fe a tu re o f polonium of b e having like a colloid in all b u t stro n g ly acid solutions ; th e sam e p e c u la rity sh o u ld be easily d etectab le in so lu tio n s o f elem ent 85. I f th is ‘eka-iodine’ is mixed w ith iodine, i t ca n n o t be p rec ip ita ted , to g eth er w ith th e la tte r, b y silver n itra te , an d i t is only p a rtly e x tra c te d b y carb o n tetrach lo rid e. I t can be deposited electro ly tically . I t is n o t p re c ip ita te d by h y d ro chloric acid, in presence o f lead. I ts fa c u lty o f form ing a v o latile h y d rid e h as n o t y e t been d em o n strated conclusively ; th is one chem ical p ro p e rty , however, can be p red ic ted w ith com plete confidence, since it d epends d ire c tly on th e p o sitio n o f an elem ent in th e Periodic Table-—w hich m u st precede a ra re gas by n o t m ore th a n fo u r places— an d is show n even by th e stillm o re m etallic elem ents polonium an d b ism u th . I t sh o u ld be n o t too difficult an ex p erim en t to com p are th e s ta b ility o f th e gaseous h y d rid e of 85 w ith th a t o f H J an d H 2Po. I t is clear from th e above th a t elem ent 85 differs in im p o rta n t reactio n s from its lower homologue iodine an d resem bles m ore its left-h an d neighbours in th e VTth period. I t is all th e m ore in terestin g th a t some sim ila rity to iodine is rep o rted in its p h y sio logical behaviour ; i t is co n cen trated in th e thyroids o f guinea pigs. I t h as I icon m entioned before th a t Mendeleeff, in som e o f h is tables, reserved room for tran s-u ran iu m elem ents. T h e ease w ith w hich in m an y cases artificial tra n sm u ta tio n g en erated elem ents higher in th e P erio d ic S ystem th a n th e b o m b ard ed ones T he first line shows th a t elem ent 85 is form ed accord n a tu ra lly led to experim ents to create th ese tran sing to expectations ; its in stab ility is, how ever, of uranides. F o r a w hile it w as believed th a t, by a a p eculiar ty p e, as in d icated b y th e second line : n e u tro n b o m b ard m en t o f u ran iu m , radioactive instead o f em ittin g p ositrons its nuclei cap tu re elem ents up to ato m ic n um ber 96 could be obtained. electrons (out of th e ff-shell) an d a re th e re b y tr a n s C areful chem ical in v estig atio n proved, however, th a t form ed in ato m s of a well-known n a tu ra l radio-elem ent m ost o f th e elem ents th u s produced were fission actin ium C', a n isotope o f polonium . T his process p ro d u cts o f u ran iu m , rad io activ e isotopes o f elem ents goes on w ith a half-value period o f 7-5 hours. p laced m uch low er in th e Periodic Table; fo r exam ple, A ctinium C has a m uch sh o rter period, only 5 x 10-3 brom ine, stro n tiu m , an tim ony, tellurium , xenon and sec. ; it is, therefore, alw ays p resent in elem ent 85 b ariu m . H ow ever, elem ent 93, th a t is, th e one mass M -|-2 m ay be form ed, th is tim e w ith em ission of two neutro n s p e r atom . T he new ly created atom s are m ostly u n sta b le ; th u s th e se tw o reactio n s give us th e possibility of producing rad io a ctiv e elem ents one a n d tw o places higher in th e P eriodic System th a n the bom barded elem ents. T h e ir applicatio n has provided ac tiv e form s o f all th re e m issing elem ents for chem ical in v estig atio n . H ere are th e m ain results. E lem ent 43, M endeleeff’s eka-m anganese, w as o b tain ed b y bom b ard in g elem ent 42, m olybdenum , w ith d e u tero n s5. A t le a st five rad io a ctiv e isotopes of atom ic n u m b e r 43 w ere recognized ; as th e ir h a lf value p eriods w ere o f th e o rd er o f hou rs a n d days, a stu d y o f th e ir chem ical behaviour w as possible. I t w as found th a t elem ent 43 can be p re c ip ita te d w ith hydrogen sulphide fro m alkaline a n d (not too) acid solutions ; th a t it can easily be deposited electroly tically ; an d th a t its oxide is v olatile. A ll th is shows th a t it resem bles m ore its higher hom ologue, rhenium , th a n its low er, m anganose. I t m a y be m entioned th a t th e id e n tity of one o f th e isotopes w ith elem ent 43 could be verified even b y th e m easu re m en t of th e K a line o f its X -ra y spectru m ; n o t in th e usual w ay, o f course, by excitin g it on th e an ticath o d e o f a n X -ra y tube, b u t th ro u g h th e sp o n taneous em ission o f th is line as a consequence o f th e tran sitio n from a higher to a low er isom eric s ta te of th e nucleus. F o r th e p ro d u ctio n o f elem ent 61 both th e atom ic reactions m entioned above h av e been successfully trie d . W hen elem ent 60 (neodym ium ) w as bom barded w ith d e u ta ro n s6, a rad io activ e isotope o f elem ent 61 w ith a ha)f-value period of a few hours was o b tain ed ; b o m b ard m en t of elem ent 59 (praseodym ium ) w ith a-particles7 resu lted in a radio-elem ent 61 o f a h a lf value p erio d o f a b o u t 200 days. I n th is case th e chem ical c h a ra c te r can lie deduced w ith g re a t c e r ta in ty from th e p osition in th e P eriodic S ystem ; elem ent 61 m u st be a rare e a rth , o f a b asicity higher th a n sam ariu m a n d low er th a n neodym ium . I t is a ta sk for th e chem ist now to te s t th is p red ic tio n w ith th e help of one of th e radio activ e isotopes o f 61, b u t scarcely a n y th in g else o f in te re st can b e expected from an investigation of invisible q u an tities o f th is now m em ber of th e raro e a rth group. F a r m ore im p o rta n t, for th e reasons given above, is th e chem ical stu d y of elem ent 85, an d it deserves special consideration also on account o f its ra d io activ e behaviour. Since th e elem ent one place low er down, polonium , is n o t available in su licient q u a n tities for a b om bardm ent, th e m ost prom ising reaction w as th e tre a tm e n t o f th e elem ent tw o places below, b ism uth, w ith helium nuclei accelerated in th e cyclotron. I t w as found th a t, bosides others, th e following sequence o f reactions took p la ce8 : 568 NATURE im m ediately following uranium , w as synthesized in an ac tiv e fo rm a n d its chem ical c h a ra c te r studied". I t seem s th a t here, too, th e sim ila rity w ith th e preceding elem ent, uranium , is g re a te r th a n w ith its low er hom ologue, rhenium . E lem en t 93 is, for exam ple, n o t p rec ip ita ted b y hydrogen sulphide in acid solution, an d does n o t possess an oxide volatile a t re d h e a t. F in ally , th e question m ay be considered how g reat is th e chance th a t th e elem ents w hich so fa r h ave only been produced artificially occur in N atu re . F o r th e elem ents 43 an d 61 it is certainly very sm all, for ex p erim en tal as w ell as th e o re tic al reasons. W e have seen th a t th e analytical-chem ical p ro p erties of elem ent 43 are v e ry m uch lik e tho se o f rhenium , an d th a t th e re is no reaso n to d o u b t t h a t elem ent 61 follows th e o th e r ra re e a rth s. N ow rh en iu m h a s been p re p a re d in h u n d red s of kilogram s, b u t n o t th e slig h test tra c e of elem en t 43 w as ever fo u n d associated w ith it. F o r elem en t 61 a special search h as been m ade, am ong o th ers, b y A uer v on W elsbach, w ho n o t only h ad u n u su a lly large q u a n titie s o f rare-ea rth m a teria l a t h is disposal b u t possessed also an u nrivalled ex p eri ence in th e ir fra ctio n al se p aratio n ; he cam e to th e conclusion t h a t no ra re e a rth existed betw een n eodym ium an d sam arium . To th is we m ay a d d th a t, q u ite in d ep en d en tly of th ese ex p erim en tal fac ts, a general ru le seem s to exclude th e possib ility of a stable elem ent 43 or 61. J . M a tta u c h 10 h a s d irected a tte n tio n to th e absence, or, a t le ast, ex trem e r a r ity , of stab le isobars ( th a t is, atom s o f equal atom ic w eight) belonging to neighbouring elem ents. I f tw o neighbours in th e P eriodic T able have isobars, one o f th e atom ic species is alm ost in v a riab ly u n sta b le , changing in to its iso b ar b y em ission o f an electron or a positro n (or both ). F o r exam ple, |jjK is isobaric w ith |g A a n d w ith Ca ; in accordance w ith M atta u cli’s R ule, IJ K em its (3-particles, th u s changing in to ft”t'a (and p erh a p s also p o sitrons, th e re b y p roducing f "A, th e astonishing te rre s tria l abu n d an ce of w hich has been te n ta tiv e ly ex plained b y th is assum ption). I f M a tta u c h ’s R ule is v alid in th e region o f th e elem ents 43 an d 61, th e re are no sta b le isotopes o f these tw o elem ents possible, as all m ass num bers are occupied b y sta b le isotopes o f th e ir neighbours. E le m en t 42, m olybdenum , possesses th e stab le isotopes 92, 94, 95, 96, 97, 98 a n d 100 ; elem ent 44, ru th en iu m , 96, 98, 99, 100, 101, 102 an d 104 ; so for elem ent 43, th e com bining w eight of w hich o u g h t to be betw een m olybdenum a n d ru th en iu m , no atom s w ith m asses betw een 94 a n d 102 are available. T he case o f elem ent 61 is sim ilar. F o r elem ent 85 M a tta u c h ’s R u le m akes no prediction, since from elem ent 84 onw ards no stab le atom s are know n. N o r are th e n egative resu lts of th e ex p e ri m en ts carried o u t so fa r in search o f th is elem ent conclusive ; fo r it w as generally supposed th a t in th e course of an aly tical separations it w ould follow iodine, w hile we know now th a t it is m uch m ore like polonium an d b ism u th . T he ta sk of a chem ist em barking to-day on a new a tte m p t a t its discovery w ould be facilitated n o t o nly b y th is know ledge b u t also b y th e o p p o r tu n ity o f adding th e artificially produced radioactive form o f elem ent 85 as an ‘in d ic ato r’ to his m a teria l ; th e a-ray s, decaying w ith th e ch a racteristic period of 7-5 hours, w ould show him a t once in w hich fractio n th e looked-for n a tu ra l elem ent, if p rese n t a t all, is c o n c en tra ted . E v en if it should be im possible to d etec t an y of th e May 23, 1942, V o l. 149 th ree m issing elem ents on th e ea rth , i t is n o t unlikely th a t th e y possess a tra n sito ry existence in th e course o f th e in n um erable therm o-nuclear reactions occurring in th e in terio r o f th e su n an d th e o th e r stars. 1 See N a t u r e , 134, 799 (1934). “ H a h n , 0 . , N a tu r w is s e n ., 14, 159 (1926). 3 M ey er, S t., H ess, V . 1’., a n d P a n e th . P . A ., S itzber. W ie n . A k a d . W iss., 123, 1459 (1914). 4 P e re y , M ., C .it., 208, [97 [(1 9 3 9 ); J . P h y s. et le R a d iu m , 10, 435 (1939). • S e a b o rg , G. T ., a n d Segife, E ., P h y s. lie v ., 65, 808 (1 9 3 9 ); SegrS. E ., N a t u r e , 143, 400 (1939). • P o o l, M . L „ a n d Q u ill, L . L ., P h y s. R e v., 53, 437 (1 9 3 8 ); L aw , H . B ., P o o l, M . L ., K u r b a to v , J . It., a n d Q u ill, L . L ., P h n s. R e v., 59, 936 (1941). 7 K u r b a to v , J . D ., M a c D o n a ld , D . C ., P o o l, M . L ., a n d Q u ill, L . 1,„ P h y s . R e v., 61, 100 (1 9 4 2 ); W u , C. S., a n d S eg i6 , E ., P h y s. R ev., 61, 203 (1942). • C o rs o n , 1). I t . , M acK en zie, K . K ., a n d S cgr6, E ., P h y s. R ev., 58, 0 72 (1940). •M c M illa n , E ., a n d A b e lso n , P . H ., P h y s . R e v ., 57, 1185 (1940). 10 M a tt a u c h , J . , P h y s . Z ., 35, 617 (1 9 3 4 ); N a tu r w is s .. 25. 738 (1937). MOSQUITO-BREEDING IN STATIC WATER SUPPLIES By J. F. MARSHALL, C.B.E. Director, British Mosquito Control Institute. countries such as G reat B ritain, w here n eith er m alaria, yellow fever n o r oth er m osquito-bom o diseases are endemic, consideration of th e h ab its of these insects in connexion w ith w ar has scarcely ever been necessary. D uring th e W ar of 1914-18, it is tru e, quite extensive o utbreaks of m alaria occurred in E n g lan d owing to th e fact th a t soldiers who h ad co n tracted th e disease abroad were sent to convalesce in d istricts w here Anopheles maculipennis, th e chief m alaria-carrier of E urope, was th en (as now) p articu la rly p rev a len t1. I t m ay p erhaps also be n oted th a t neglect of ag ricu ltu ral drainage during th a t w ar led to a m arked (and in some cases serious) increase in th e m osquito infestation of m an y lowlying areas of G reat B ritain. N eith er of th e above-m entioned co n tacts between B ritish m osquitoes an d war, however, a ttra c te d more th a n local in te r e s t; an d it w as only in th e early p a r t of la st year, w hen fire-fighting au th o rities com m enced to in stal v ery large, open-air ta n k s all over th e co u n try , th a t an y such association can be said to have become a m a tte r of general concern. A lthough public know ledge regarding m osquitoes is extrem ely lim ited, m ost people are aw are of th e fact th a t static w ater is liable to encourage th em : hence th e ap p e ar ance of these conspicuous receptacles th ro u g h o u t our u rb a n areas has u navoidably given rise to considerable apprehension. I t seems therefore advisable to con sider, first, how far these misgivings are justifiable ; and, secondly, to w h at e x te n t precau tio n ary m easures can an d should be adopted. I n theory, th e ‘co n tro l’ of m osquitoes is a co m p ara tiv ely sim ple m a tte r, owing to th e fac t th a t b oth th e ir larv al an d p u p al stages of developm ent are passed en tirely in w ater. M osquitoes of th e Culicine trib e (to w hich all b u t four of th e B ritish species belong) breed exclusively in sta tic w ater ; b u t those o f th e A nopheline trib e breed also (and in th e case of m an y species chiefly) in running w ater— th eir larva) being able to anchor them selves to surface weeds by m eans of certain hook-ended hairs. I t th u s follows th a t m osquito-control operations include (in addition I n No. 3786, M ay 23, 1942 NATURE to th e obvious procedure of abolishing po ten tial breeding-places b y drainage, filling-in, etc.) the clearing an d re-grading of ditches an d th e rem oval of aq u atic vegetation. I t frequently happens, how ever, th a t lack of tim e (or of funds) renders such m easures im practicable, in w hich case an alternative m ethod is to kill the larv;e, either b y spraying oil upon, or m ixing ‘larv icid al’ chemicals w ith, th e infested w ater. In th e form er case th e oil dissolves aw ay a hydrofuge secretion from w ithin th e breathing orifices of th e la rv a a n d th e n enters th e tracheal system w ith fa ta l re su lts 2 ; in th e la tte r case th e larv a is poisoned w hen it feeds. F or larvicidal p u r poses p reparations based on coal ta r derivatives an d introduced into 30,000-50,000 tim es th eir own volum e of th e infested w ater are m ost com m only em ployed. I t is im p o rta n t to note, however, th a t w ater should on no account be tre a te d w ith either oil or larvicide if th e presence of m osquito larva! has n o t been actually observed : tre a tin g uninfested w ater being n o t only a sheer w aste of b o th tim e and m oney b u t also liable to destroy fish, w ater bugs an d various other ‘m osquito enem ies’ th a t n a tu ra l collections of w ater so frequently contain. A lthough all th e above-m entioned operations are simple in them selves, th e practical application of them is a m uch m ore com plicated m a tte r th a n it sounds. This is chiefly due to th e num erous idiosyncracies th a t characterize different species of m osquitoes, n o tab ly in regard to th e q u ality and environm ent o f th e w ater th a t th e y instinctively select for oviposition. (Some B ritish species lay th eir eggs separately on w ater ; others lay them sep arately on land liable to flooding ; others stick them tog eth er during laying, so as to form ‘eggra fts ’. The species Culex pipiens, G. molestus and Theobaldia annulata belong to th e last-m entioned group.) O f th e th irty species a t present know n in G reat B ritain, seven have been b u t rarely recorded, b u t th e hab its of th e rem aining tw en ty -th ree have been m ore or less thoroughly studied. O f th e species included in th e la tte r group, eight are know n to breed chiefly in w oodland pools ; three, exclusively in rainfilled cavities in trees ; tw o, alm ost exclusively in slow-running, w eedy w ater ; two. chiefly, an d one, exclusively, in th e sa lt or brackish w ater of coastal m arshes—an d so on. The coastal species have an exceptionally long flight-range and are consequently able to cause annoyance in localities several miles d istan t from th e ir breeding-grounds. In regard to th e breeding of m osquitoes in tan k s, reservoirs an d oth er containers, it has u n til recently been believed th a t only tw o B ritish species—nam ely Culex p ipiens Linnaeus an d Theobaldia annulata Schrank—are a t all likely to do so. O f these tw o m osquitoes, th e form er breeds im partially in either clean or foul w ater ; th e la tte r chiefly in w ater contam inated b y sewage or other nitrogenous m a tte r. U nder n a tu ra l conditions, C. pipiens rarely, if ever, bites hum an beings (its custom ary victim s being birds), b u t T . annulata avidly does so. These facts indicate th a t tan k-sto red w ater, unless allowed to become contam inated in th e m anner above m en tioned, is unlikely to give rise to an y ‘m osquito an noyance’ other th a n th e possible public apprehen sion th a t th e sight (or sound) of a n y species of m osquito is liable to arouse. A lthough, however, this assum ption m ay still hold tru e where ta n k s in open-air situ atio n s are concerned, it would be unsafe to consider it generally applicable u n til th e breeding h ab its of an o th er B ritish m os 569 quito, nam ely, C ulex molestus Forskal, have been m ore fully investigated. B o th in th e larval an d ad u lt form s th is species resembles C. pipiens so closely th a t its presence in G reat B ritain rem ained u n n oticed u n til 1931, w hen it w as accidentally discovered a t H ayling Islan d (H an ts)3. Previous to its being fo u n d in G reat B ritain , th e presence of G. molestus in o th er p a rts of E u ro p e (for example, in F ran ce4, G erm any'', Greece6, H u n g ary 6 an d M alta6) had alread y been detected, a n d its biology studied, by C ontinental an d o th er entom ologists, who considered it to be an abnorm al ‘v a rie ty ’ o f G. pipiens rath er th a n a sep arate species. T he a u th o r’s reasons for preferring th e la tte r classification have been fully expounded elsew here7. To say th e least, th e biological peculiarites of C. molestus are extrem ely striking. O f th e two th o u san d odd species o f m osquitoes a t present described, less th a n a dozen are know n to be stenogam ous (th a t is, able to m a te in a v ery sm all space) an d only th ree to be autogenous (th a t is, able to lay fertile eggs w ith o u t h aving h a d a blood m eal before or a fte r m ating). N o t only does C. molestus differ from b o th C. p ipiens an d T . annulata in being b oth stenogam ous an d autogenous, b u t it also differs from th e form er species in being an extrem ely fierce ‘manb ite r’ w henever o p p ortunities occur. I t was suggested th a t th e detectio n of G. molestus in G reat B rita in m ight su p p ly th e long-aw aited ex planation of m ysterious cases, rep o rted from tim e to tim e, in w hich h um an beings h ad been fiercely b itte n (n otably in houses an d tu b e railw ays in London) b y m osquitoes diagnosed as G. pipiens. The accuracy o f th is suggestion was afterw ards established b y th e investigation o f ‘molestus plagues’ occurring in houses in H u ll9 ; in houses in W estm inster and o th er Tham es-side d istricts of L ondon (for example, B attersea, Berm ondsey, Chelsea, D eptford, Fulham a n d Greenwich) ; an d in various statio n s of the already m entioned tu b e railw ays. I n ad d itio n to being b o th stenogam ous an d a u to genous, C. molestus is also hom odynam ic ( th a t is, able to breed a t an y tim e of th e y ear provided th a t ex tern al conditions rem ain favourable). Possessing these th ree u nusual characteristics, it is v ery easily bred in th e la b o ra to ry all th e y ear ro u n d ; b u t, in sp ite of th is fact, our knowledge regarding its n atu ral breeding h ab its is u n fo rtu n ately far from complete. I n th e case of th e tu b e railw ays, however, larvse of th is species were found to be heavily infesting collections of w ater sta g n atin g u n d er sta tio n p la t form s an d betw een th e lines. T hey h av e also been found in flooded cellars an d cesspools, in underground system s of household w aste disposal, in septic tanks, in cavities w ithin a w ater-logged ru b b ish dum p and in th e underground ta n k s of a Tham es-side laundry. C onsideration o f th e above an d certain other facts h av e led some entom ologists to suggest th a t C. molestus m ay breed chiefly in w ater which, in u rban an d other b u ilt-u p localities, is allowed to stag n ate in d ark , underground situ atio n s ; an d since, b o th in L ondon an d elsewhere, sta tic w ater is now being stored in th e basem ents of m any houses, th e possi b ility of C. molestus being th u s provided w ith facilities for extending th e range of its undesirable activ ities app ears to be fa r from rem ote. (Should a n y such developm ents occur, th e covering of ven tilato rs, window openings, etc., to p rev en t gravid females of th is species from reaching th e water, m ig h t p erh ap s b e deem ed advisable.) I t is obviously im p o rta n t th a t ta n k s of th is k in d should be k ep t NATURE 570 u n d er observation, an d specim ens of any m osquito la rv a seen collected for identification. W h eth er even th e ‘m an-ignoring’ G. p ip ien s is likely to breed in th e very large outdoor ta n k s th a t are now in use is still a m a tte r for speculation. Should such cases occur, th e question of applying oil or larvicide m erely to allay public apprehension m u st presum ably receive consideration. I t has to be noted, however, th a t oil is extrem ely injurious to ta n k s w ith bitum inous linings. As already m entioned, tan k -sto red w ater th a t is allowed to become co ntam inated b y sewage or other nitrogenous m a tte r will very prob ab ly becom e infested w ith larvae of th e m an-biting species T. annulata. A tte n tio n has, m oreover, been directed to th e possibility of tank-stored w ater becom ing a su itab le breeding m edium for certain of our m ore ‘countrified’ species, owing, for exam ple, to algal d evelopm ent or to th e accidental or mischievous in tro d u ctio n of vegetable or other organic m a tte r. I t is, how ever, obviously preferable to deal w ith such contingencies if an d w hen th e y arise ra th e r th a n to a d o p t th e sp e n d th rift policy—advocated in some q u arte rs— of indiscrim inately tre a tin g enorm ous n u m bers o f ta n k s on th e off-chance of a few of them containing m osquito larvae. These creatures are so easy to recognize th a t anyone who has ever seen one— w hether in a specim en tu b e or a ta n k — can have no difficulty w hatever in deciding w hen an ti-larv al m easures are necessary. 1 M a rsh a ll, J . F ., “ T h e B r itis h M o sq u ito e s ” , ]>. 319 ( B ritis h M u se u m 1938). 2 K e ilin , n . , T a te , P ., a n d V in c e n t, M ., P arasitology, 27, 257 (1935). ” M a rs h a ll, J . F ., a n d S ta le y , ,T., N a t u r e , 135, 34 (1935). 4 R o u b a u d , F ., C .R . A c a d . S e t , 188, 735 (1929). 5 M acG reg o r, M . E ., T ra n s , lio v . Soc. T r o p . M e d . a n d H y u ., 26, 307 (1932). 6 T a te , P ., a n d V in c e n t, M ., P arasitology, 28, 512 (1934). 7 M a rs h a ll, J . F ., a n d S ta le y , J . , Proc. R o y . E n t. Soc., A , 1 2 ,1 7 (1937). 8 M a rsh a ll, .T. F ., a n d S ta le y , J . , P arasitolooy, 27, 4 (1935). 9 M a rs h a ll, J . F .. a n d S ta le y , ,T., N a t u r e , 136, fi41 (1935). 10 S h u te , P . G ., L a n cet, 1, 0 (1941). SCIENCE AND WAR* By AUSTIN H. C LA R K U.S. National Museum ROM th e earliest tim es of w hich we have a record to th e p resent day, th e history of m an has been m arked b y co n stan t changes in th e social system s, changes th a t often were a b ru p t an d violent. One form of social stru c tu re or of governm ent has suc ceeded another. Small b u t pow erful social or political un its have grow n b y accretion or by conquest into g reat kingdom s or em pires. These kingdom s or em pires eventually have decayed or fallen ap a rt. T ogether w ith these freq u en t social, political, or economic read ju stm en ts of th e p a s t we see a constant an d fairly continuous developm ent of other forces w hich to a large ex ten t are independent of tran sien t political conditions. W e n o te a growing interest in an d u n d erstanding of th e products of th e e a rth and th e ir uses. W e also are able to trac e th e everincreasing subjugation of th e forces of N ature, w hich m ore an d m ore come to be th e servants instead of th e enemies of m an. T he g rea test of all hum an achievem ents w as th e control and use of fire. W e have no knowledge of F * S u b s ta n c e o f th e a d d re s s o f th e r e tirin g p re s id e n t o f th e W a s h in g to n A c a d e m y o f S ciences d e liv e re d a t th e 3 0 9 th m e e tin g o f th e A c a d e m y o n J a n u a r y 10. May 23, 1942, V o l. 149 w hen or how fire was first transform ed from a te rrify ing n a tu ra l phenom enon in to m a n ’s m ost useful serv an t. Second am ong h u m an achievem ents was th e fashioning an d use of tools an d weapons. The origin of th e use of tools is lost in th e far d istan t p ast. T hen cam e th e w eaving of textiles from p la n t or anim al fibres an d th e m oulding of p o tte ry vessels, followed b y th e appearance of bronze. N o t long after th e appearance of bronze utensils of various sorts, th e wheel an d axle appeared in Asia, soon spreading to E urope. F ro m th e Bronze Age onw ard th e know ledge of th e use of n a tu ra l pro d u cts an d th e control of n atu ra l forces have shown a fairly continuous developm ent. Since th e beginning of th e present cen tu ry th e adv an ce in th e know ledge an d und erstan d in g of th e prod u cts an d forces of N atu re has been g reater th a n in all th e thousands of years preceding— or a t least since th e su b ju g atio n of fire, th e first fashioning of tools, an d th e dom estication of anim als an d plants. W h eth er we like th e idea or n o t, we are now living in an age, an d u n d er conditions, in w hich science plays a do m in an t p a rt, an d th e established scientific principles th a t underlie m an y of th e m ost fam iliar of our p resen t-d ay im provem ents were u n h eard of, or considered fallacious, no longer th a n a generation ago. This is self-evident to all ; b u t th e im plications inseparable from a culture based ever m ore intensely an d extensively on increasingly ab stru se science are n o t as y e t fu lly appreciated. T he progress th a t th ro u g h th e ages has been m ade in th e u n d erstan d in g of n a tu ra l phenom ena an d in the u tilizatio n of n a tu ra l products is continuing a t an accelerated pace, an d will continue in th e future, in spite of w h at m ay h appen in th e n ex t few years. I t m ay be locally o bstructed, or even b ro u g h t to an end, b u t somehow, somewhere, it will carry on. The present struggle is no m ore a contest in th e m ilitary field th a n it is in th e field of science. I t is quite possible to win th e W ar on th e b a ttle front, b u t lose it in th e lab o rato ry . W e m u st see to it th a t, so fa r as possible, th e stead y advance of science is m aintained. A t th e present tim e we are utilizing to th e m axim um ex ten t our scientific resources an d our scientific personnel to aid in our w ar effort. B u t th is is n o t enough. V arious branches of science n ot of im m ediate m ilitary application are in th e long run quite as essential for our progress an d our welfare as are those form s of engineering, of physics, an d of chem istry th a t underlie th e construction and th e use of m odern im plem ents of w arfare. These are th e m an y an d v aried ty p es of p u re science, lines of w ork leading to results seem ingly of no im portance, th a t all too often are regarded m erely as a form of m ental exercise u n d ertak en solely for th e persona] satisfaction an d gratification o f th e person con cerned. W h a t we call p ure science is sim ply a branch of science for w hich no economic application has as y et been found. B u t a t an y tim e a body of unco ord in ated facts m ay suddenly and unexpectedly fit in to an in teg rated whole, to our advantage. W ith o u t its advance fringe of com petent w orkers in p ure science co n stan tly probing th e g reat unknow n a n d accum ulating m asses of d a ta w ith no ap p aren t im m ediate application, th e b roader aspects of scientific progress soon w ould languish. P ure science is likely to suffer severely in tim es like the present— in tim es when it w ould seem to be the wisest course to give it th e m axim um encouragem ent. I n th e dem ocracies, progress in an y line of science is m ainly dependent upon th e willingness of the people No. 3786, M ay 23, 1942 NATURE to su pp o rt w ork in th a t p a rtic u la r line which, in tu rn , is dependent upon p opular in terest an d appreciation. T here are people w ho are b y no m eans sciencem inded. T heir a ttitu d e varies all th e w ay from passive superciliousness to outspoken hostility. W e who are engaged in scientific w ork, an d who u n d er sta n d its im portance in th e general com plex of present-day h um an affairs, often fail to realize how recently science has been able m ore or less success fully to overcom e various form s of popular p re judice an d to secure th e favour of a very large section of th e general public. The p resen t po p u lar a ttitu d e tow ards science c a n n o t properly be understood w ith o u t some know ledge of th e public a ttitu d e in th e m ore or less recent p ast. I propose, therefore, to digress here in order to indicate briefly th e changes th a t have ta k e n place here and in E ngland since th e early days of th e settlem ent of th e U nited S tates. A t th a t tim e, in the reign o f Queen E lizabeth, Galileo was still a stu d e n t a t th e U niversity of Pisa, Tycho B rahe h a d ju st com pleted his observatory, an d P aracelsus and Agricola only recently h a d died. In those days science was alm ost wholly included in th e subject of theology, an d scientific w ork was restricted w ithin narrow bounds b y th e dogm as of th e theologians. F o r some tim e th e re h ad been a growing restiv e ness against th e restrictions placed on scientific investigations b y th e theologians. This restiveness began to ta k e th e form of concerted action in th e first h alf of th e seventeenth century. As early as th e reign o f Charles I , ab o u t 1615, there existed in E ngland an organization referred to by th e H on. R o b e rt Boyle, seventh son of th e first E arl of Cork, as th e “Invisible College” . T his “Invisible College” w as first suggested b y T heodor H a a k (or H ank), a G erm an from th e P ala tin a te, th e n resident in London. I t consisted of w eekly m eetings a t w hich th e results of experim ental w ork in philosophy, in its b road sense, were discussed. This was ra th e r an unorthodox procedure for th e tim e, b u t those who atten d e d th e m eetings were am ong th e ab lest m en of E ngland, an d included theologians as well as others. One of th e theologians was D r. Jo h n W ilkins, afterw ards Bishop of Chester, who h ad m arried R obena, sister of O liver Cromwell. A nother p a r tic ip a n t was Sir C hristopher W ren, who la te r laid down th e plan for th e College of W illiam and M ary. According to D r. Cromwell M ortim er, “h ad n o t th e Civil W ars happily ended as th e y did, Mr. Boyle and D r. W ilkins, w ith several other learned m en, w ould have left England, and, o u t of esteem for th e m ost excellent an d valuable G overnor, John Wintivrop th e younger, w ould have r e tir’d to his new -born Colony [Connecticut] an d th e re have established th a t Society fo r promoting N atural Knowledge, w hich those G entlem en h ad form ed, as it were, in Embryo am ong them selves” . E m igration to Am erica was, however, forestalled. On N ovem ber 28, 1660, th e “ Invisible College” becam e visible as “T he R oyal Society of L ondon for Im proving N atu ra l K now ledge” . On th e W ednesday following, w ord was bro u g h t th a t K ing Charles I I approved th e design of th e m eetings ; in O ctober 1661, th e K ing offered to be entered as one of th e Society ; and in th e n ex t y ea r th e Society was incorporated under th e nam e of th e R oyal Society, th e first ch a rter of incorporation passing th e G reat Seal on J u ly 15, 1661. A lthough the R oyal Society rem ained in E ngland, b o th the College of W illiam and M ary and H arv ard 571 College received considerable am o u n ts of m oney from th e estate of Boyle a fte r his d ea th in J a n u a ry 1691-02. Science now began to assum e a new aspect. Charles I I h ad in effect declared th a t th e re is nothing irreligious in rep o rtin g facts. So records of observed facts an d th e ir in te rp re tatio n in th e light of other facts began to supersede introspection in w hich th e aid of facts was regarded as superfluous, com bined w ith interm inable com m entaries on th e w orks of A ristotle. Follow ing th e R esto ratio n , science in B ritain becam e largely an occupation of th e aristo cratic and th e w ealthy, a n d for th e m o st p a r t w as followed along lines th a t h ad little or no economic application. I n th e public m ind it came to be identified m ore or less com pletely w ith th e aristo cracy an d to be regarded as p arta k in g of th e sam e aloofness from th e general ru n of hum an affairs th a t characterized th e social life of th e u p p er classes. T he n a tu ra l resu lt of th is was th a t w hen, in th e V ictorian era, th e cham pions of th e lower classes began to gain a considerable following, th ey , or a t least m a n y of them , a tta c k e d science as one of th e perquisites of th e aristocracy. T his a ttitu d e is well illu strated by Charles D ickens’s “Mudfog P ap ers” published on th e occasion of th e first m eeting o f th e B ritish A ssociation for th e A dvancem ent of Science. Since th a t tim e science in E n g lan d gradually has come m ore an d m ore in to p o p u lar favour. Applied science has m ade rap id strides an d is now q u ite as fully developed an d as highly regarded as it is in a n y o th e r lan d . T he rise in th e prestige o f applied science, how ever, has n o t been accom panied b y an y noticeable decline in th e p o p u la rity of p ure science, so th a t here we find th e tw o ty p e s advan cin g side by side in m ore or less ideal balance. B u t, u n fo r tu n a tely , science in B ritain still does n o t have th e com plete confidence of th e public, a n d is n o t b y an y m eans free from neglect, disparagem ent, or even a tta c k in th e popular Press. I n th e U n ited States th e h isto ry of science has been som ew hat different. In early Colonial tim es scientific effort was devoted m ainly to m aking know n th e n a tu ra l resources of th e new land, p articu larly th e p la n t anti anim al life. B u t applied science early a ttra c te d th e atte n tio n of th e colonists. In later Colonial tim es applied science, especially in certain engineering branches, was sy stem atically discouraged in th e fear th a t th e Colonies m ight become com p etito rs of th e m o th er co u n try in th e p roduction of m an u factu red goods. I t was possibly p a rtly as a reaction from th is suppression th a t afte r th e R ev o lution science stood high in th e favour of th e rep re sen tativ es o f th e A m erican people, its m o st insistent an d pow erful advocates being T hom as Jefferson of Virginia, B enjam in F ran k lin of P ennsylvania, an d Jo h n A dam s o f M assachusetts. B u t it w as som e tim e before the new co u n try was sufficiently well organized to enable th e people to devote m uch th o u g h t to science. W hen th e y did, a sp ontaneous in terest, ta k in g various stran g e an d crude form s, appeared, p articu la rly in th e ag ricu ltu ral areas. This crude p opular science—an d pseudo-science—g rad u ally b e cam e am algam ated w ith th e m ore orthodox science o f th e schools an d colleges, a n d we note, especially a fter th e m iddle of th e la st century, a n enorm ous expansion of applied science in all form s, la te r v ery largely supported b y F ederal an d S tate ap p ro p ria tions m ade possible by active a n d w idespread interest am ong all th e different groups in our population. 572 NATURE I n th e United. S tates p opular in te rest in science is twofold, arising b o th from th e v ista of economic b etterm e n t resulting from applied science, an d from its appeal to th e im agination. W e all like to look forw ard to th e d ay w hen we shall be even m ore com fortable th a n we are now. B u t we all have a n on-m aterial side. W e like to get aw ay from th e h ard realities of everyday life and to contem plate th e unknow n, an d beyond th a t th e unknow able. W e all would like to know m ore a b o u t th e w orld we live in. W h a t w ould we find a few hun d red m iles down in th e earth , or 20,000 feet below th e surface of th e sea ? W e w ould like to know m ore ab o u t th e sta rs : A re th e re any oth er w orlds like ours ? A nd w h a t is it like in in terstellar space ? W e w ould like to know m ore ab o u t u ltim ate hum an origins—indeed, ab o u t v ery m a n y things concerning w hich our p resent infor m ation is vague an d fragm entary. Now although p o p u lar in te rest in science is m ore general a n d m ore w idespread in th e U nited S tates th a n it is in m ost o th er countries, it tends to g ra v ita te in these two directions, tow ards th e directly economic an d tow ards th e m ysterious. Betw een these tw o extrem es lies a broad, in term ediate field in w hich th e A m erican people as a whole tak es little interest, b u t w hich is intensively cu ltiv ated elsewhere. This is th e de scrip tiv e b ranch of p u re science, th e results of w hich are of no im m ediate economic im port an d are n o t m ysterious. P o p u lar in te rest in science m u st n o t only be m aintained, it m u st also be increased if we are to hold our own in th e years to come, for w hether carried on u nder G overnm ent su p p o rt or in endowed in stitu tio n s of learning, th e full developm ent of our scientific potentialities is dependent upon a sy m p a th e tic public a ttitu d e . In order to secure, to m a in ta in an d to increase public interest in and sy m p a th y tow ards scientific work, an d to convert th e still d is concertingly numeroife unbelievers, it is essential th a t we continually provide th e public w ith news regarding scientific progress in all lines of in te rest to them , from b o th th e m a terial an d non-m aterial or philo sophical points of view. Such im personal news is especially desirable in tim es of natio n al em ergency. F o rtu n a te ly , in th is respect th e U nited S tates is in an excellent position. More an d b e tte r science appears in its daily Press an d oth er journals th a n in those of m o st other countries, an d science is less freq u ently disparaged an d denounced th e re th a n elsewhere. F o r th is we have chiefly to th a n k th e N atio n al A ssociation of Science W riters, th e m em bers of which, in addition to know ing science, know th e public m ind an d are able to p resent th e advances in science in term s everyone can understand. P rogress in science is possible only w ith th e supp o rt o f an in terested and appreciative public. I t is also possible only thro u g h th e efforts of a carefully selected a n d adequately train ed personnel. T his is a m a tte r th a t heretofore has scarcely received th e atte n tio n it deserves. A t th e present tim e a very serious danger to our continued progress in science has arisen. T his is the in tro d u ctio n into th e A rm y of m an y young m en who w ould be o f v astly greater value to th e co u n try if th e y were p erm itted to continue th eir studies, or to rem ain in research positions. T he m a tte r is fu rth e r com plicated b y th e fac t th a t as a rule th e m ost valuable of these young m en are those m ost likely to enlist on th e ir own initiative. A fter th e W ar of 1914-18 th e re was a m arked scarcity o f able young scientific m en. This was m ost May 23, 1942, V o l. 149 noticeable, perhaps, in th e biological sciences, though it w as m ore or less noticeable in o th er branches as well. M any prom ising young m en were killed. O thers, as a resu lt of several years spent in th e various arm ies, found them selves unable to m ake th e neces sa ry rea d ju stm e n t to scientific w ork. Still others trie d to rea d ju st them selves b u t were only p artially successful. B reaking th e th re a d of co n tin u ity of effort betw een th e im pressionable boy in th e fo rm a tiv e period an d th e m a tu re m an cannot b u t result in a certain am o u n t of dislocation. W e are rem inded of th e old B erber proverb : “Teaching boys is like ploughing earth, Teaching m en is like ploughing rock, Teaching old m en is like ploughing w ate r.” T here are tw o w ays out of th is dilem m a. E ith e r th e stu d e n t m ay be placed on a deferred list so th a t he m ay be enabled to continue his studies u n in te r ru p ted ly , or he m ay be assisted in carrying on his work, to w hatev er degree m ay be found practicable, while in th e Services. M any young b o tan ists an d zoologists would w el come an o p p o rtu n ity for collecting specim ens and continuing th e ir studies in regions new an d strange to them . Such m aterial as th e y collected could to sen t hom e to be identified, or to be stored u n til th eir arrival. A ctivities of th is n a tu re carried on in th eir spare hours would go far tow ards overcom ing th a t feeling of boredom th a t afflicts alm ost everyone statio n ed a t an isolated arm y p o st or n av al base, and there is no reason for believing th a t these activities would in an y w ay d e tra c t from th e ir m ilitary effi ciency. N o t only w ould th is w ork benefit th e men engaged in i t ; it w ould also go far tow ards filling m any gaps in our know ledge of th e d istrib u tio n of anim als an d p lan ts, and o f o th er features connected w ith th e m . In arm y posts an d n av al bases a young zoologist or b o ta n ist who spends his spare tim e catching insects or pressing p la n ts will a t first be an object of ridicule to his associates, b o th officers an d men. H is situ atio n , how ever, is b y no m eans w ith o u t precedent— an d m ost honourable precedent. I t m ay com fort him to realize th a t th e w orld’s leading a u th o rity on th e Hesperiidfe, a peculiarly difficult group of butterflies especially characteristic of Am erica, is B rigadier G eneral W illiam H . E v an s of th e R o y al Engineers, while in th e R oyal N av y R ear A dm iral H u b e rt L ynes is th e leading au th o rity on a very puzzling group of sm all A frican birds. Some tim e ago th e collections o f th e B ritish M useum were enriched b y a fine collection of butterflies presented by C aptain L ord Byron. Looking a t th e m a tte r in a m ore frivolous light, is a young m an using his spare tim e to continue his studies, an d a t th e sam e tim e to advance our know ledge of anim als an d plants, an y m ore ridiculous th a n an ancient tough old sea-dog in th e forecastle engaged in fine em broidery w ork w ith delicately coloured silks, to th e accom panim ent of blood-curdling o aths ? A v a st am o u n t of such w ork has been done b y the personnel of foreign arm ies an d navies in th e p ast, p articu larly b y officers in th e B ritish services. In fact, a t one tim e th e U n ited S tates N av y assigned in terested young officers to th e S m ithsonian I n s ti tu tio n for in stru ctio n in th e collection an d preserv a tio n of m aterial. W h eth er in its m aterial or in its non-m aterial aspects, progress in science is d ependent upon th e fostering of th e scientific spirit. T he scientific sp irit is m ore th a n m ere curiosity. I t is an insatiable No. 3786, M ay 23, 1942 NATURE curiosity th a t impels one to learti everything th a t is know n ab o u t a given subject, an d th en to go fu rth e r a n d broaden a n d extend th a t know ledge by personal investigation an d research, in spite of all difficulties an d discouragem ents—an d theso are alw ays m any. T he sp irit of science is inborn, though it m ay appear in anybody, anyw here, in an y class, or group, or race. In order to develop th e scientific sp irit to th e m axim um , as it m u st be developed if we are to hold our place in th e w orld of th e futu re, we m u st w atch for it a t its inception, an d w henever an d w herever it is found encourage it. STATISTICAL CONTROL OF PRODUCTION* By DR. C. G. D A R W IN , F.R.S. National Physical Laboratory OR a num ber of years I h a d been interested in th e general question of tolerances, first from the point of view of pure science an d la ter in its more practical aspects. My in te re st in th is subject was very m uch focused w hen I cam e to th e N ational Physical L aboratory, w here I found th a t w ork was being done on th e ac tu a l verification of m a n u fa ctu r ing an d inspection gauges ; th is w ork, of course, deals w ith th e su b je ct in an enhanced degree— squared, so to speak, because th e re is n o t only to be considered th e tolerance of th e w ork, b u t also th e tolerances on b o th th e go an d th e not-go gauges w hich are to check th e work. F rom internal evidence of th e gauge draw ings, it looked as if some of th e tolerances w ere assigned m uch closer th a n should be necessary, an d I sta rte d to tr y to find o u t how th e y h a d been fixed. T o accom plish this, on every occasion w hen I m et an engineer I asked him how he decided th e tolerances in his b ranch of th e sub ject ; I fear I bored a g reat m any people a t th is tim e. I got a v arie ty of answers w hich som etim es explained things a b it, b u t often not a t all, an d th o u g h I discussed it w ith q u ite a num ber of m en, m an y of them occupying prom inent places in different branches of th e profession, I came aw ay w ith th e im pression th a t scarcely an y of them were really interested in the sub ject of tolerances. To exaggerate th e pictu re w hich I got as th e result of m y inquiry, I concluded th a t in designing a new m achine th e chief engineer drew it free-hand w ith dimensions to th e nearest inch, a n d sen t it to the d rau g h tsm an to w ork out th e detail to th e nearest th ousandth, who th e n gave it to his junior assistan t to m ark in th e tolerances. Instru ctio n s were certainly always given th a t tolerances should be as easy as possible, b u t only lip service was done to them , and th e ju n ior assistant, anxious n o t to get him self into trouble, would, as a general rule, th in k of th e sm allest num ber he knew an d th e n halve it. This is a carica ture, of course, an d h as some of th e ab su rd ity of one, b u t also perhaps ju s t a little of th e resem blance. Seriously, it seem ed to m e th a t th e re w as a defect in th e h a b it of th o u g h t of m a n y in th e engineering profession, an d th a t som e so rt of cam paign was needed to inculcate in people’s m inds th e idea th a t every n um ber has a fringe, th a t it is n o t to be regarded as ex act b u t as so m uch plus or m inus a b it, a n d th a t F * F r o m a p a p e r b efo re a jo in t m e e t i n g o f t h e I n s titu tio n s o f C ivil, M ech an ical a n d E le c tric a l E n g in e e rs h e l d o n A p ril 15. 573 th e size of th is b it is one of its really im p o rta n t qualities. W ith o u t an y v ery clear idea of where to catch hold of th e subject, I h a d full in ten tio n of try in g to do som ething a b o u t it a t th e tim e I w ent to th e U nited S tates a year ago. T here I cam e across th e m eth o d of ‘sta tistica l co n tro l’ of m ass production, an d it was obvious a t once th a t th is is th e rig h t approach. Sim ilar w ork has been done in G reat B ritain too, in p articu la r b y th e staff of th e General E lectric Com pany a n d b y m em bers of th e R oyal S tatistical Society, an d it w as p erhaps ill-luck th a t I never cam e across it before crossing th e A tlan tic ; b u t th a t I did n o t shows th a t it was n o t v ery widely know n. I w ould ad d th a t it is n o t b y an y m eans v ery widely used y e t in th e U n ited S tates, though th e use is spreading. I n b o th countries it has been principally used in industries associated w ith elec tricity , such as th e telephone in d u stry , b u t I w an t to em phasize th a t it should be of even g reater im p o rt ance in th e m echanical industries, an d th a t it is specially applicable to a business like th e m anufac tu re of m unitions in all th e ir aspects. One of th e im p o rta n t p oints in th e new m eth o d is th a t it gives reasoned in stead of guessed values to th e tolerances. I will ta k e as an exam ple th e m aking o f tim e fuses for an ti-aircraft, an d I am giving aw ay no m ilitary secrets in doing so, since I shall in v en t th e d a ta a n d miss o u t a lo t of o th er considerations th a t w ould really enter. Suppose th a t th e leth al area of a b u rstin g shell is such th a t, if it explodes w ith in a te n th of a second of th e set tim e, it will m ake a kill. T he gunner therefore dem ands of th e m an u factu rer th a t he m ake a fuse w ith accuracy a te n th of a second. T he m an u factu rer w orks o u t his m ethod, b u t finds th a t w hereas it is easy to get one to a fifth of a second, he will h av e a lo t of tro u b le to g et to a te n th , and, indeed, he estim ates th a t for th e sam e effort of w ork an d cost h e could n o t hope to g et m ore th a n a q u a rte r as m an y fuses if th e y m u st have th e accuracy of a te n th . Now h alf his shells will b u rst w ith in th e range I asked for an d so, in fact, I shall be wise if I accept his inferior fuse, since I shall th ereb y get four tim es as m an y shells of w hich h alf will do w h a t I w an t, an d I shall therefore double th e ra te of killing. I need n o t say th a t I h av e over simplified th e business ; on one side I have m issed o u t th e cost of th e other p a rts of th e shells, an d on th e other, I h av e forg o tten th a t th e gunner has u n certainties of range to consider, so th a t his dem and for a te n th of a second is m ore ex act th a n he can ju stify for p ractical use. My exam ple is in ten d ed to show th a t it is good business for th e user an d th e m ak er of an y article to g et to g eth er before deciding th e tolerances of m an u facture. T he user m ay be inclined a t first to feel th a t in doing th is he is surrendering some of his freedom of choice, b u t if y o u consider it closer you w ill see th a t th is is n o t so. H e has n o t g ot an y real freedom of choice, since he m u st surely tr y to design th e article so as to be as easy to m ake as possible, b u t he has foregone th e q u a n tita tiv e inform ation of w h at will in fac t prove to be easy, a n d above all of w h at thing, easy to m ake, will be good enough for th e job. I m ay sum m arize th is aspect of th e m a tte r b y saying th a t th e user h as ten d ed to dem and th a t everything should be m ade for him as well as possible, b u t he ought to w an t every th in g to be m ade for him as b ad ly as possible, or perhaps n o t quite th a t, b u t as b ad ly as perm issible. I t is in th is aspect th a t sta tistica l control specially gives th e rig h t inform ation. 574 NATURE T here are a good m an y varieties of procedure called for in th e circum stances of applying sta tistic a l con trol. F irst, th e re are th e tw o classes according to w hether it is a q u a n tity or a q u ality th a t is concerned. I t m ay be a m easure, say, of a length or perhaps an electrical resistance, w hich has to fall w ithin certain prescribed lim its ; for th is wo can m easure each specim en an d record it for analysis. In other cases th e te st is q u alitativ e, in th a t th e specim en either passes a te s t or fails to pass—for exam ple, a vessel is w a te rtig h t or n o t ; an d even th e m easure of a length m ay fall in th is class if it is te ste d w ith a gauge, so th a t th e answ er is given in th e form th a t it passes or fails to pass th e gauge. T hen there is an o th er distin ctio n th a t divides either ty p e of w ork in to tw o classes. Some tests, such as a m easure of length, can be applied to every article m ade b u t o th er te sts are d estru c tiv e of the specim en ; for exam ple, th e te st of th e force of a n explosive or of th e tensile stre n g th of a bar. In th is la st case th e te st m u st of necessity only be done on a sam ple, an d it is obviously im p o rta n t to ta k e th e sam ple as sm all as perm issible. Moreover, even in th e case w here every specim en could be tested, there will be g rea t econom y in only doing it for a sam ple ; so th a t, in fact, we m ay reckon th a t sam pling is one o f th e m ain features of th e process, an d to determ ine th e advisable fractio n of th e whole n um ber th a t m u st be sam pled is an im p o rta n t p a r t of th e d u ty of th e sta tistician . T hen again th e practical problem of sta tistic a l control itself falls in to tw o p a rts, for there is first th e business of sta rtin g a new process and g ettin g it in to sta tistica l control, an d th e n th e busi ness of carrying it on later, after th e control has been established. All these m a tte rs are described in th e British S tandards In stitu tio n publications B.S. 1008 an d 600 (revised), b u t I shall co n ten t m yself w ith giving a very crude sketch of a single exam ple. T he exam ple I shall ta k e is based on one I le arn t ab o u t in th e U n ited S tates, an d I am intentionally leaving th e details incorrect an d falsifying some of th e facts. I le arn t a b o u t it from Colonel Simon, who F ig . 1. has show n g reat brilliance in developing th e m ethods for m unitions in th e U .S. arsenals. T he subject was a p articu la r ty p e of tim e-fuse, and th e gunners h ad assigned certain lim it s of tolerance w hich are described in th e d iagram (Fig. ]). T he m anufacturers all had g reat tro u b le in satisfying th e dem and for th e longer tim es, so th a t th e tolerances were exceeded bo th ab o v e an d below, an d Simon w as called in to set M ay 23 , 1942, V ol. 149 th e m a tte r rig h t. This he did, b u t to simplify the sto ry we will im agine he h ad been in a t th e sta rt, an d describe how th e process m ig h t h av e gone. I t is first necessary to be sure th a t th e process is ‘in con tro l’, in th e technical sense of th e term . We ta k e a considerable b atch of th e fuses, keeping th em sorted according to tim e an d place of m anufacture. Group these sets (or p ro b ab ly sam ples of them ) in batches of five an d set th e fuses a t 20 sec. Tim e each fuse, an d w ork o ut th e m ean of each b atch an d its ‘ran g e’, th a t is to say, th e difference betw een th e shortest an d longest am ong th e five. These are m arked on tw o c h arts in a w ay described on th e B ritish S tandards In stitu tio n publication (Fig. 2). F ro m th e ‘range’ ch art it is possible w ith th e help of tables th a t have been co n stru cted b y statistician s to draw on th e other a p air of lim its w ith in w hich th e dots should fall. P erhaps th e y will n o t do so ; say th e d o ts for fuses m ade by one p articu la r tool fall outside. T his gives sure know ledge th a t som ething is w rong w ith th e process— th e sta tistician cannot say w h at, th o u g h I was told of cases w here he could go so far as to say either th a t th ere was only one th in g w rong or else certainly several things wrong. I t is for th e engineer to re exam ine his process an d find th e fau lt. N ext, of course, sim ilar w ork m u st be done a t th e oth er fuse settings. Suppose th is h as been done, an d th a t th e whole system is in control, an d th a t th e accuracy is good enough for th e user. A fter th is, m uch less sam pling is needed, b u t every so often a group should be ta k e n an d te ste d in th e sam e w ay ; I will n o t go in to detail, b u t th is sam pling will nearly always give w arning of pending trouble, before th e trouble is so b ad th a t th e fuses w ould actu ally fail in passing th e ir test. R e tu rn in g to th e ac tu al h isto ry of these fuses, Simon p lo tte d average tim e an d ‘ran g e’ for batches of five fuses a t various tim ings of th e fuse, an d got the curves I show (Fig. 1) for th e average tim ing an d for th e d o tte d lines on eith er side between which all values will fall. T his was for th e fuses of one m an u factu rer, an d th e re were sim ilar curves, some up an d some down, for th e others. I t will be seen th a t th e fuses m ostly failed to fulfil specification a t 20 sec. an d above, an d y e t th eir tolerance was m uch finer th a n th a t w hich h ad been specified. This could be overcom e in a v arie ty of w ays ; for exam ple, by reg rad u atin g th e m arkings of th e tim e on th e fuse. T he resu lt w as th u s th a t an article w hich system atic ally failed to pass its te st, was, w ith a q uite triv ial change, found to be actu ally b e tte r th a n h ad been asked for. I m ay ad d th a t as a consequence of his w ork Simon found th a t th e old te sts h ad destroyed som ething like twice as m any of th e fuses as is now necessary. No. 3786, M ay 23, 1942 NATURE I will conclude w ith a few general rem arks. W hen 1 first came across th e m eth o d I knew it w as of th e greatest im portance, b u t I dou b ted if th e m iddle of a w ar w as th e tim e to s ta r t it. I asked th is very question of tw o of th e experts in th e Bell L aboratory, an d b o th con trad icted th is first th o u g h t of m ine and said th a t it could be applied piecem eal to one p ro cess after another w ith o u t delay in production. T hen, as showing how quickly people could a d a p t th e m selves to it, I m ay recount an incident I experienced. Im m ediately after visiting Colonel Simon, I happened to be a t F ra n k fo rd A rsenal, w hich in peace-tim e was th e principal facto ry m aking am m unition for th e U.S. Arm y. As such, I expected it w ould be ra th e r con servative an d th a t it m ight be suspicious of new fangled m ethods, a n d I therefore asked one of th e chief colonels th e re w h at he th o u g h t of these m ethods, w h ich , I m ay em phasize, are q uite new in th e ir applica tio n to m ilita ry stores. H is reply w as th a t it seemed th e only sensible w ay of doing th e business. A nother p o in t well w orth consideration is th a t m any w orks have already existing a m ass of d a ta of th e k in d used b y th e statistician , b u t th e y do n o t subm it them to th e sam e analysis. In such cases th e change of procedure w ould be only slight, a n d a greatly im proved control w ould be obtained by applying th e sta tistica l m ethod. Thirdly, th e m ethod gives inform ation ab o u t the size of sam ple th a t should be tested. In some cases it m ay be inadequate, w hereas in others it will be found th a t testin g a m uch sm aller sam ple would give sufficiently reliable inform ation on th e quality of th e whole. W e cannot, of course, expect th a t th e m ethod is a panacea for all troubles, a n d I expect in some cases it will be tried an d prove u nsuitable ; b u t I will v en tu re th e forecast th a t th e opposite will m uch m ore often be th e case, a n d th a t m a n y processes to w hich a t first sight it seems inapplicable will la ter be found to benefit greatly b y th e intro d u ctio n of statistical control. OBITUARIES Mr. W . P. Pycraft W illiam P lane P yckaft , who died on M ay 1, was a well-known ornithologist an d com parative anatom ist. H e was born a t G reat Y arm o u th in 1868 an d while a schoolboy was a ttra c te d to n a tu ra l history b y th e w ild life of th e N orfolk Broads. H e becam e a keen observer of all living things, b u t devoted him self specially to birds. A fter leaving school, he desired to follow n a tu ra l histo ry as a profession, an d sta rte d as a p riv ate pupil w ith th e cu rato r of th e L eicester M useum, w here he learned th e a rt of preserving and preparing anim als for stu d y and exhibition. In 1892 he was introduced to Prof. (afterw ards Sir) R a y L ankester, who invited him to be his assistan t in m aking p reparations for th e O xford U niversity Museum. W hile th u s occupied he atten d ed L an k ester’s lectures and dem onstrations, an d th u s extended his outlook b y acquiring a good knowledge of th e stru ctu res an d relationships of anim als. W hen L ankester was appointed director of th e B ritish M useum (N atural H istory) in 1898, P y craft accom panied him to L ondon an d becam e his tem p o rary assistan t there. Soon afterw ards he joined th e perm anent staff of th e Zoological D e p a rt m en t of th e Museum, w here he rem ained as an 575 assistan t u n til his retirem en t in 1933. H e sp en t his la ter life a t Longcross n ear Chertsey, Surrey, in surroundings w here he could continue th e field observations w hich he h a d begun in early youth. T he original researches carried o u t b y Mr. P y craft w ere concerned chiefly w ith th e an ato m y of birds. H is first paper, published in th e Ib is in 1895, d e scribed an d discussed th e arran g em en t of th e feathers in th e Tinam ous, an d in 1898 he co n trib u ted a m em oir on th e feathering o f th e owls to th e T ra n s actions o f the L in n ea n Society. Betw een 1898 and 1907 he w rote a v aluable series of nine p apers on the osteology of birds published in th e Proceedings o f the Zoological Society, an d in 1900 he discussed th e m orphology an d phylogeny of th e Pakeognatha; an d N eognatha; in an extensive m em oir in th e T ra n s actions of th e sam e Society. Mr. P y craft also began to ta k e m uch in terest in th e v ariatio n s of th e h u m an skull, an d in 1915 he proposed to su b stitu te for th e F ra n k fo rt b ase line an o th er line w hich passed w holly th ro u g h the cranium avoiding th e u p p er p a r t of th e face. This proved to be n o t generally acceptable, anti he retu rn ed to th e su b ject in a p ap er in M a n in 1925. H e w rote several accounts of h um an skulls, th e m ost n o te w o rth y being his description of th e Boskop fossil from South Africa in th e Journal o f the Royal A nthro pological In stitu te of 1913, an d a description of th e R hodesian fossil skull in a B ritish M useum volum e in 1928. H e took p a r t in several discussions on th e P iltdow n skull, a n d in 1917 published in Science Progress an account of th e lower jaw w hich po in ted o u t its differences from th e jaw of an ape. Mr. P y craft was also a prolific w riter of popular books an d articles on n a tu ra l history, w hich b ro u g h t him a large correspondence an d n o t infrequently led to th e discovery of new facts. H is first p o p u lar books were th e sm all “ Stories of B ird L ife” , “F ish Life” an d “R eptile L ife”, published b y Newnes in London betw een 1900 an d 1905. “A H isto ry of B ird s” , a m ore serious work, appeared in 1910, an d his “ Birds of G reat B rita in ” followed in 1934. H is volum es on th e “ In fan cy of A nim als” , “T he Courtship of A nim als” (1913) an d “Camouflage in N a tu re ” (1925) are especially readable an d contain original observations. H is w eekly article in th e Illustrated London N ew s was a m uch-appreciated feature of th is p ap e r for m an y years, an d a ttra c te d wide atten tio n . In all his w ritings Mr. P y craft show ed g reat in terest in th e possible m ode of evolution of th e various stru ctu res an d h ab its w hich he described, and an address on “ Some N ew A spects of E v o lu tio n ” w hich he delivered to th e N orfolk an d N orw ich N a tu ra lists’ Society in 1935 w as rep rin ted in th e an n u al rep o rt of th e S m ithsonian In stitu tio n , W ashington, in th e following year. B is sty le was som etim es forceful, for w hen he h ad form ed an opinion he could n o t readily be p ersu ad ed th a t it m ig h t be m istak en ; b u t he h a d a versatile m ind an d was alw ays inspiring. H e is m ourned b y a large circle of friends who learned th e m ore to appreciate him th e closer th e y were associated w ith him . A. S. W o o d w a r d . W e reg ret to announce th e following d eath s : Prof. Charles Cohen, form erly of th e Brussels P aste u r In stitu te , aged sixty-one. D r. R . L. D itm ars, th e distinguished herpetologist, form erly cu ra to r of m am m als an d reptiles in New Y ork Zoological P ark , on M ay 12, aged sixty-five. 576 NATURE D r. B ern h ard Fischer-W asels, professor of m orbid a n ato m y a t Frankfort-on-M ain, president of the G erm an Pathological Society an d ed ito r of th e F rankfurter Zeitschrift fiir Pathologie, aged sixtyfive. Sir Jam es L arm or, F .R .S ., form erly L ucasian p ro fessor of m athem atics in th e U niversity of Cambridge, on M ay 19, aged eighty-four. Prof. B. Malinowski, professor of anthropology in Y ale U niversity, form erly U niversity professor of anthropology in th e London School of Econom ics, on May 16, aged fifty-eight. D r. C. H a rt M erriam, founder in 1885 an d u n til 1910 chief of th e U nited S tates B ureau of Biological Survey, now know n as th e F ish and W ild Life Service, on March 19, aged eighty-six. M ay 23, 1942, V o l . 149 D r. Jo h n Miller, director of aircraft production (factories), form erly chief engineer, London and N o rth -E a stern R ailw ay (N .E. A rea), on M ay 16. T he R ev. T. E . R . Phillips, a p ast-p resid en t of th e R oyal A stronom ical Society an d of th e B ritish A stronom ical A ssociation, on M ay 13, aged seventyfour. D r. G. G. Stoney, F .R .S ., who for m any years was associated w ith C. A. P arsons an d Co. L td ., p articu larly in connexion w ith th e developm ent of th e steam tu rb in e , on M ay 15, aged seventy-eight. Prof. G. A. W itherington, form erly professor of m ath em atics in th e R o y al N aval College, Greenwich, on M ay 1, aged sixty-nine. Prof. W . J . Young, professor of biochem istry in the U niversity of M elbourne, aged six ty -th ree. NEWS and VIEWS W orld Mineral Resources and Post-War Needs I n th e fo u rth clause of th e A tlantic C harter, Mr. Roosevelt an d Mr. Churchill s ta te “th a t th e y will endeavour, w ith due respect for th e ir existing obliga tions, to fu rth e r enjoym ent b y all S tates, g reat or small, v icto r or vanquished, of access, on equal term s, to th e tra d e an d to th e raw m aterials of th e world w hich are necessary for th eir economic p ro s p e rity ” . T he D ivision for th e Social an d I n te r national R elations of Science of th e B ritish Association is therefore arranging a conference on “R aw M aterials and In d u strial Needs : M ineral Resources an d O u t look” , to be held in London a t or ab o u t th e end of Ju ly . As Sir R ichard Gregory, president of th e Association, pointed o u t in subm itting th e proposal for such a conference, th e w orld’s n a tu ra l resources —b o th organic an d inorganic—are m uch too large a subject to be d ea lt w ith in a single conference, b u t a survey of th e p resent position of m inerals of industrial im portance, w ith suggestions for fu rth e r investigations into th e ir geographical distributions an d research into th e production of su b stitu tes, will show th e close contact betw een science an d fu n d a m en tal n ational an d in tern atio n al problem s. The Conference will indeed be sim ilar to a jo in t m eeting of th e Sections of Geology, G eography, Physics and Chem istry a t an annual assem bly of th e B ritish Association, an d its papers will be of th e n a tu re of contributions to a rep o rt upon th e distribution, o u t p u t an d in d ustrial uses of th e chief m ineral deposits of th e world. Such energy resources as solid, liquid and gaseous fuels belong to a class of th eir own, an d th e facts relating to them have been brought before a num ber of W orld Pow er Conferences. W hatever is know n ab o u t th e n atu re , d istribution an d uses of m inerals in th e e a rth ’s cru st has been gained by scientific inquiry, an d th e knowledge is in ternational in origin an d scope. B y presenting th e chief facts as to n a tu ra l resources of m inerals and th eir geographical control, such a conference can do m uch to prom ote recognition of th e interdependence of nations an d th e need for collaboration betw een them . Scientific Workers of the Argentine D u r i n g la st M arch, Prof. E . D. A drian, professor o f physiology in th e U niversity of Cam bridge, paid a v isit to th e A rgentine a t th e in v itatio n of th e A rgentine N ational A cadem y of Medicine. H e was welcomed w ith m uch cordiality an d w as frequently assured of th e sy m p a th y of A rgentine m edical men an d scientific w orkers for th e Allied cause. Tow ards th e end of his visit, Prof. A drian w as asked to receive a d ep u tatio n from th e Comisi6 n S an itaria A rgentina de A y v d a a las D em ocracias (H ealth C om m ittee to Aid D em ocratic Countries). This d ep u tatio n asked Prof. A drian to convey a m essage of solidarity to m em bers of th e m edical profession a n d scientific men in G reat B ritain . T he C om m ittee said th a t th e exam ple se t b y B ritish m en of science w orking in th e ir laboratories an d clinics, holding congresses even in w ar-tim e to prom ote th e application of scientific discovery to th e progress of m ankind, an d arranging th e co-ordination of th e scientific w ork of G reat B ritain , th e U .S.S.R . an d th e U n ited S tates, stren g th en s th e ir fa ith in th e triu m p h of dem ocracy th ro u g h science. This v ery cordial m essage from th e A rgentine will be received w ith m uch satisfaction b y scientific w orkers in G reat B ritain , who will be en couraged to pursue th e course th e y h av e set for th e m selves in helping to rid th e w orld of to talitarian ism . Illuminating Engineering Society A t th e an n u al general m eeting of th e Illu m in atin g E ngineering Society on M ay 12, Mr. W . J . Jones (president) was able to p resen t an encouraging record for th e p a st session. A featu re h as been th e fu rth e r developm ent of centres a n d groups, of w hich there are now eleven, an d w hich are expected to do useful w ork in stu d y in g th e lighting requirem ents of special local industries. T he position in reg ard to th e Society’s w ork on A .R .P . lighting, und ertak en jo in tly w ith th e M inistry of H om e Security, has for th e tim e becom e stabilized, b u t a n u m b er of com m ittees are now exploring various aspects of lighting in relatio n to after-w ar reconstruction. T he “R ecom m ended Values of Illu m in atio n ” p u t forw ard by th e Society (I.E .S . Code) has been ad o p ted by th e M inistry of Supply, th e A d m iralty an d th e M inistry of A ircraft P roduction, in applying th e F actories (Standards of L ighting) R egulations (1941). M any m em bers of th e Society are engaged in th e ta sk of designing lighting in stallations for factories engaged on n atio n al w ork. T he Society in 1940 in itiated th e practice of conferring fellowship on those of its m em bers having th e requisite technical qualifications. The n um ber of fellows created is now 96—ra th e r less no. 3786, M a y 23, 1942 NATURE 577 th an te n per cent of th e m em bership of th e Society. Industry in Scotland The new president for th e forthcom ing session is I n th e discussion in com m ittee in th e H ouse of Mr. R . O. Ackerley. Commons on M ay 1 2 on th e estim ates for th e Scottish The Illum inating Engineering Society m ade a H om e D ep artm en t, Mr. T . Jo h n sto n , S ecretary of practice, in th e years preceding th e W ar, of inviting S tate for Scotland, gave a su rv ey of in d u stria l develop an em inent expert from abroad to deliver an address m en t in S cotland since 1918. H e referred to th e on th e occasion of each annual m eeting. T his p ractice advisory com m ittee on Scottish in d u stry w hich has is no longer possible in th e p resent circum stances, been set up, an d expressed th e hope th a t b y its b u t its own m em bers h ave filled th e gap. The lecturer m eans th e in d u strial afte rm a th in S cotland of 1914on May 12 w as Mr. G. H . W ilson, who took for his 18, due to concentration on h eav y industries for subject “ S treet L ig h tin g : P a st, P resent and F u tu re ” . export, will be avoided. In th e course of th e d is Mr. W ilson rem arked th a t th e period 1928-38 was cussion, Sir Jo h n G raham K err p u t in a plea for the one of g reat technical progress. An outstanding developm ent of a v a rie ty of sm all lig h t industries. event in 1928 w as th e erection of fifty model lighting T he in d u strial b e lt of S cotland has grow n in its installations illustrating th e eight classes of the p resen t position because th e sources o f pow er are B ritish sta n d ard specification. This led to a recogni close a t h an d . In d u stry ten d s to d rift to th e more tion of th e im portance of ro ad surface brightness as populous p a rts of th e co u n try — in S cotland to th e a facto r in relation to visibility. D uring th e ten-year so u th — an d one w ay of stopping th is d rift is to carry period tw o new sources, th e sodium an d m ercury pow er all over th e co u n try . T he tra n sp o rt of pow er v apour lam ps, were introduced. T heir unusual is o f v ita l im portance. In th e form of coal an d oil, spectra raised new problem s an d th e ir shape an d su b ject to road or rail tra n sp o rt, pow er is only dis size m ade necessary considerable changes in the trib u te d w ith difficulty an d a t relativ ely high cost. design of lanterns. A tte n tio n w as also devoted to T he new er m eth o d of d istrib u tio n o f pow er through th e problem of th e siting of posts, w hich was dis an electric grid m ig h t h av e a trem endous influence cussed in th e rep o rt of th e d ep artm en tal com m ittee on Scotland an d its industries, for, b y these means, appointed b y th e M inistry of T ran sp o rt appointed in th e site of in d u stry is no longer tie d to th e source of 1934. A fter referring briefly to lessons to be learned power, an d th e feeding of sm all u n its becomes feasible. from our experience of th e low orders of illum ination available during th e present black-out, Mr. W ilson reviewed after-w ar problem s. H e pointed o u t th e Austrian Scientific W orkers in Great Britain A n A ssociation of A u strian Engineers,, Chemists possibilities of th e new fluorescent lam ps, express ing th e belief th a t technical resources are enormous. an d Scientific W orkers in G reat B rita in has recently The fu tu re of stree t lighting, he affirmed, depends been form ed. The m ain activities of th e A ssociation largely on th e ex ten t to w hich th e scientific a ttitu d e will be to assist m em bers in th eir professional w ork of m ind is em ployed in th e application of th e achieve an d interests, to represent th em w ith th e au thorities, to prom ote co n tact an d relations w ith B ritish col m en ts of research—for exam ple, in connexion w ith leagues an d to form a link w ith B ritish scientific bold experim ents in tow n planning. an d technical in stitu tio n s. L ectures, courses an d discussions will be held an d will give o p p ortunities Fluorescent Lighting A p a p e r o n th is subject, read recently by L. J . for th e exchange of views an d to discuss m a tte rs of Davies, H . R . R uff an d W . J . S cott before th e I n s ti m u tu a l interest. I t is hoped th a t th e Association tu tio n of E lectrical E ngineers in London, gives a m ay assure th a t b e tte r use is m ade of th e know ledge an d abilities of A u strian engineers, chem ists b rief histo ry of fluorescent lighting an d follows this b y a description of a ty p ical m ains-voltage tu b u la r a n d scientific w orkers w ho are anxious to assist in th e w ar effort. T he actin g chairm an of th e A ssociation fluorescent lam p an d th e principles of its operation. T he new fluorescent lam p com bines th e high efficiency is D r. F . E hrenfest-E gger ; inquiries should be sent of th e straig h t electric discharge lam p, w ith m uch of to th e ho n o rary secretary, Mrs. K . H ilfreich, 133 th e convenience of operation of th e incandescent H ath e rley Court, London, W .2. L ectures are being lam p, while possessing, in addition, special charac given on th e first M onday of each m o n th . E v ery teristics of low brightness, exceptional colour- M onday, com m encing Ju n e 1 , a t 7 p.m ., a clubrendering power, a n d com parative absence of rad ia n t room will be open for m em bers of th e A ssociation h eat. The 200/250-v., 80-w att lam p an d its auxiliaries, a t th e A u strian Centre, 69 E to n A venue, N .W .3, m arketed in G reat B rita in in M arch 1940 to im prove w here th ere will be o p p ortunities to read technical factory lighting in b lackout conditions, are described periodicals an d to m eet other colleagues. in detail an d th e characteristics an d com ponents of A Relic of Dr. John Dee th e com plete u n it are explained. T his lam p is 5 ft. long an d in. in diam eter, ta k in g 0-8 am p. a t a T h e sale b y Messrs. S otheby of an in terestin g relic lam p voltage of 115 ; its nom inal lum inous efficiency of th e m ath em atician an d astrologer D r. J o h n Dee, is 35 lum ens/w att an d its m ean brightness is 3-3 who was patro n ized b y Queen E lizab eth , was recorded candles/sq. i n . I ts high electric pow er/light con in The T im es of M ay 5. T he relic is a gold disk 3J in. version ratio is exam ined together w ith th e con in d iam eter weighing 1 oz. 4 dw t. 5 gr., bearing th e ventions w hereby these are assessed. T he paper L ondon d a te le tte r for 1589 an d engraved w ith a concentrates a tte n tio n upon th e practical features of d iagram of th e “ Vision of th e F o u r C astles” w hich th e lam p, b u t gives a sufficient description of th e ap p eared to his m edium E d w ard Kelley, on th e physics involved to prom ote an appreciation of b o th m orning of J u n e 20, 1584, a t a house in St. S tephen’s th e present characteristics an d fu tu re im portance of S treet, Cracow, w here th e tw o m en w ere staying. this ty p e o f light source. T he au th o rs conclude th a t T he d iagram is reproduced in “A T rue a n d F aith fu l th e lam p is satisfactorily fulfilling a p resent industrial R elatio n o f w h a t passed for m any Y ears betw een need, an d th a t its qu ality has been so g rea tly ap p re D r. Jo h n D ee . . . an d some S p irits” published in ciated th a t it is u ndoubtedly th e forerunner of a new 1659 b y D r. Meric C asaubon. T he disk was b ought series o f lighting lam ps. b y th e B ritish M useum for £230. 578 NATURE Institution of Electrical Engineers Awards T h e Council of th e In stitu tio n of E lectrical E ngineers has m ade th e following aw ards of prem ium s for papers read during th e session 1941-42, or accepted for publication : In stitution P rem ium to Mr. J . M. Meek ; A yrton P rem ium to Mr. J . S. F o r r e s t; Fahie P rem ium to D r. W . C. R adley an d Mr. E . P . G. W right ; John H opkinson P rem ium to D r. A. L. Williams an d Mr. L. E . Thom pson ; K elvin P rem ium to Mr. E . Colin Cherry ; Overseas P rem ium to Prof. K . A ston an d Mr. M. V. ICesava R ao ; E xtra P re m ium s to D r. A. H . M. A rnold, Mr. G. W . Bowdler, Messrs. G. W . Bowdler and W . G. S tandring, Mr. R . D avis, D r. H . D. E inhorn an d P ro f. B. L. Goodlet, D r. H a c k e tt an d Mr. A. M. Thom as, Mr. E . A. R ichards, Mr. V. Sia, Messrs. R . C. W oods an d A. S. M acD o n ald ; Installations Section P rem ium s to Messrs. L. J . D avies, H . R . R u ff a n d W . J . Scott (Crompton Prem ium ), Mr. R . Grierson ; M eter and Instrum ent Section P rem ium s to Messrs. E . A. B urton, J . S. F o rrest an d T. R . W arren (Silvanus T hom pson Prem ium ), Mr. D. J . Bolton ; T ransm ission Section Prem ium s to Mr. J . W . L each (Sebastian de F erra n ti Prem ium ), Messrs. W . Casson a n d F . H . B irch ; Wireless Section P rem ium s to Mr. O. S. Puckle (Duddell Prem ium ), D r. D. C. E spley a n d Mr. D. O. W alter (Ambrose Flem ing P rem ium ), Messrs. J . E. T hw aites an d F . J . M. L aver. Earthquake in Ecuador R e p o r t s have been received from G uayaquil, th e chief p o rt of E cuador, th a t a severe ea rth q u ak e took place in th e interior on th e n ig h t of M ay 13-14. G uayaquil itself was severely shaken for some 60 seconds according to h u m an perception, an d buildings collapsed. I t is estim ated th a t ab o u t sixty people lost th eir lives. Mr. J . J . Shaw ’s seism ograph a t W est Brom w ich recorded a severe earth q u ak e a t 2h. 25m. 52s. t j . t . on M ay 14. F u rth e r news is aw aited. I t will be recalled ( N a t u r e , F eb. 11, 1939, p. 238) th a t several earthquakes shook a considerable area in E cuador including th e tow ns of Vallechillos and Quito on th e n ig h t of F eb ru ary 1, 1939. On th a t occasion th e volcano Cotopaxi erupted. Earthquakes Registered at Kew Tw o strong d ista n t earthquakes have recently been recorded a t K ew O bservatory. T he first, on April 8, 1942, began recording on th e vertical com ponent a t 15h. 53m. 58s. t j . t . im pulsively, and on th e N an d E com ponents a t the sam e tim e P was em ergent. The shock p robably originated some 11,000 km . distan t, a t m axim um a tta in e d an am pli tude of 410 (J. a t Kew, an d finished recording a t 19h. 20m. t j . t . T he second, on April 13, began recording im pulsively on all th ree com ponents a t 07h. 55m. 48s. u . t . from an epicentral distance of 6,130 km ., a tta in e d a m axim um am plitude of 94 and finished recording a t lOh. 00m. u . t . All readings are te n tativ e. Betw een April 15 an d M ay 5 eighteen earthquakes were registered b y th e seism ographs a t K ew O b servatory. All these shocks gave rise to sm all am pli tudes w ith th e exception of th e ea rth q u ak e of A pril 20. This began recording a t 08h. 52m. 40s. u . t . and finished recording a t lOh. 25m. t t . t . T he in te rp re ta tio n of th is record is a t present te n tativ e, though a n epicentral distance of 125° is possible. M ay 23, 1942, V ol. 149 The Ipswich Man T h e skeletal rem ains know n as th e Ipsw ich m an, w hich have been housed a t th e R o y al College of Surgeons, London, since th ey w ere discovered in Bolton an d Co’s brickfield, Ipsw ich, in 1911, have now, th ro u g h th e in stru m en tality of Mr. R eid Moir, an d th e kindness of th e president an d Council of th e College, been presented to th e Ipsw ich Museum. Since 1911 a g reat deal has been discovered regarding th e age of these rem ains, which were th o u g h t originally to be older th a n th e U pper Chalky Boulder Clay— a deposit of one of th e m ajo r glaciations of E a s t Anglia. I t now seems clear th a t th e skeleton is referable to one of th e prehistoric floors situ ated in th e slopes of th e ad jacen t valley, an d examples of flint im plem ents, etc., found in these floors are exhibited w ith th e h u m an bones in th e entrance hall of th e Ipsw ich Museum. Though all th e geological and archfoologieal aspects of th is m a tte r are n o t y e t com pletely understood, it is highly probable th a t th e Ipsw ich m an lived in th e earlier p a rt of U pper Palaeolithic tim es, and is of considerable an tiq u ity . Announcements P ros’. E . H . A lto n , reg istrar an d professor of classics in T rin ity College, D ublin, who represented th e College in th e D ail from 1923 un til 1937, when the U niversity rep resen tatio n w as abolished an d he was elected to th e Irish Senate, has been appointed provost of th e College in succession to th e late Dr. W . E . T hrift. Mr . H arry B r ear I iEy , th e w ell-know n steelm aker of Sheffield, has been elected to h o n o rary m em ber ship of th e Iro n an d Steel In stitu te . Mr. B rearley’s recen tly published au to b io g rap h y was review ed in N a tu re of A pril 11, p. 397. T h e B ritish S tan d ard s In stitu tio n has been recognized b y th e G overnm ent as th e sole organiza tion for th e issue, in consultation w ith an y G overn m ent, professional or in d u strial bodies concerned, of sta n d ard s having a n atio n al application. I n regard to th e p rep aratio n an d issue of codes of practice for building an d civil engineering work, th e M inister of W orks an d Buildings is m aking special arrangem ents b y th e ap p o in tm en t of a rep resen tativ e com m ittee w ith w hich th e In stitu tio n is co-operating. As from th e com m encem ent of n ex t session, th e nam e of th e M eter an d In stru m e n t Section of the In stitu tio n of E lectrical E ngineers will be altered to “M easurem ents Section” . T he Section will include w ithin its scope all m a tte rs relating to electrical m easurem ent an d control, th e design an d application of th e ap p a ratu s, an d th e m aterials em ployed in connexion w ith them . A d i s c u s s i o n on “ Soviet M etallurgy” , arran g ed by th e F a c u lty of Science, M arx H ouse, will bo held a t th e London School of H ygiene an d T ropical Medicine, K eppel S treet, W .C .l, on M ay 28 a t 7 p.m . The discussion will be based on a p ap er b y Mr. Tom B arker, w ho took a leading p a r t in th e creation of th e g rea t K uzbas M etallurgical Com bine in Siberia. T ickets of adm ission, including a copy of Mr. B arker’s paper, can be o btained from M arx House, Clerkenwell Green, London, E .C .l, price 2a. No. 3786, M a y 23, 1942 NATURE 579 H ouely records of th e in te n sity o f cosmic rays h av e been m ade during th e p a s t year. T he ap p a ratu s used consisted of a b a tte ry of Geiger counters register ing a b o u t 25,000 threefold coincidences each hour. The circuit used gave a negligibly sm all n um ber of casual coincidences. No absorbing screens were used, b u t prelim inary experim ents w ith lead showed th a t th e thickness of th e counter walls was sufficient to th e o th er tim e v ariations. A detailed account of th e results of th e w ork will be given elsewhere. I t will be show n th a t th e changes from d ay to d ay in cosmic rays, w hen corrected for changes in atm o spheric ab sorption, are well correlated w ith th e v aria tions in h eig h t of th e atm ospheric layer of given pressure a t w hich mesons are supposed to be formed. This is consistent w ith B lac k ett’s ex p lan atio n on th e basis of th e in stab ility of th e meson. W hen th is effect is elim inated from th e observations, th e n th e well-know n world-w ide changes appear w hich are associated w ith th e disturbances of th e te rrestrial m agnetic field. These changes are being stu d ied in detail. In th is le tte r an account is given of th e rem arkable changes of cosmic ra y in te n sity associated w ith th e c u t o u t all radioactive ray s a n d th e v ery soft cosmic rays. To count such a ra p id ra te of coincidences w ith o u t loss, a W ynn-W illiam s’ scale-of-two co u n ter 1 was used. F o r this circuit th e resolving tim e is so reduced th a t, a t th e counting ra te of 400 p er m inute, th e n um ber of particles w hich is m issed is n o t m ore th a n one p er thousand. T he n um ber of pulses re corded b y th e telephone counter is photographed au to m atically every hour. T he whole ap p a ratu s was p repared in th e P hysical L aboratories a t th e U niversity of M anchester, an d th e observations are being m ade in a room a t th e top of th e Im perial College o f Science, South K ensington. T he observations began in F eb ru ary 1943, b u t th e photographic recording sta rte d only in A pril. The first phenom enon to w hich a tte n tio n w as given was th e so-called te m p eratu re effect of cosmic rays, n o t only because of its im portance in itself, b u t also so as to be able to elim inate th is influence from the observations a n d th u s to establish m ore accurately m agnetic sto rm of M arch 1, 1941. T he figure shows th e observed tim e v ariatio n from F eb ru ary 27 to M arch 6 . T he decrease of n early 12 p er cen t on M arch 1 is certainly u nusually g reat, and, so far as is know n to us, is th e largest v ariatio n of th is kind so far recorded. T he points on th e diagram rep resen t th e m ean value of th e cosmic ra y in te n sity d u rin g a period of th ree hours. T he scale is in percentages from th e norm al value. T he cosmic ra y distu rb an ce began sh o rtly before th e onset o f th e m agnetic storm . F ro m inform ation kindly given b y th e R oyal O bserva to ry , th e la tte r began a t 7h. 27m. on M arch 1. Allowing for th e sta tistica l fluctuations ( ± 0-36 per cent for th e three-hour period), it ap p ears th a t th e cosmic ray s distu rb an ce began ab o u t one h o u r earlier. T he sto rm subsided rap id ly afte r 1 a.m . on M arch 1 an d finished th ree hours later. A fter th e first rap id recovery of ab o u t h a lf th e initial drop, w hich occurred w ithin tw e n ty hours of th e onset, th e recovery was v ery slow an d w as n o t com plete b y th e six th day. LETTERS TO THE EDITORS The Editors do not hold themselves responsible fo r opinions expressed by their correspondents. No notice is taken of anonymous communications. Cosmic Rays and Magnetic Storms NATURE 580 I t is rem arkable th a t th e m agnetic storm was n o t so intense as some others w hich have been accom panied b y a less violent disturbance in cosmic rays. The extrem e range in th e horizontal m agnetic force H was 512 y, equivalent to less th a n 3 p er cent of th e H value. Nevertheless, it appears th a t th e b rig h t eruption w hich began to be observed on th e sun 19h. 27m. earlier was one of th e m ost extensive recorded, lasted for an unusually long tim e an d p ro duced a m uch larger m agnetic effect th a n usual. Also a special feature of th e sto rm w as a series of 27 g ian t pulsations in H and V w hich lasted from I5h. 5m. to 17h. 3m. on M arch 1, an d are, it seems, unique in th e A binger records. I t w as ju s t in th is in terv al w hen th e n u m b e r of cosmic particles reached its low est value. T he m ean of th e tw o-hourly ob serv a tions centred a t 16h. an d 17h. represents a decrease in th is n um ber of 12-0 ± 0-44 p er cent. F ro m th e record of th is an d oth er storm s, i t seems clear th a t, a t an y ra te in these latitu d es, th e re is no sim ple p roportionality betw een geom agnetic an d cosmic ray s disturbances. A. Im perial College of Science an d Technology, D ep a rtm en t of Physics, London, S.W.7. M ay 6 . 1 W y n n -W illiam s, C. I:.. R e p . r r o a . 3, 239 (1937). Dispersion of Cellulose Strands in Cell W alls I n a recent le tte r in N a t u r e 1 P rof. Frey-W yssling directs atte n tio n to th e im portance in cell w all studies of th e angular dispersion of th e co n stitu en t cellulose micelles an d refers to m y papers as ignoring th is p ro p erty. Cell w all physics is a stu d y in w hich there is already m uch controversy, a n d it seems th e re fore a p ity to give th e im pression of a difference of opinion w here none actually exists. T he question centres ro und th e desirability of ta k in g in to account n o t only th e ‘parallel’ te x tu re said to be ty p ical of fibres b u t also th e so-called ‘dispersed’ or ‘re tic u la r’ te x tu re p resent in some o th e r cell typ es. So far as I am concerned, th e difference betw een ‘p arallel’ an d ‘dispersed’ te x tu res is one o f degree only an d actually, far from ta k in g “ . . . only parallel te x tu res into account . . .” , 1 have y e t to in vestigate a single cell in w hich I am convinced th a t th is te x tu re does occur in an y th in g like a stric t sense. In some fibres 2 an d wood cells3, for exam ple, w here Frey-W yssling h im self supports parallel te x tu re , an d in some collench y m a4, m y collaborators an d I have show n th a t th e an g u lar dispersion of th e cellulose micelles ab o u t th e ex tinction direction m ay be considerable an d is p ro b ab ly of im portance in explaining certain optical properties of th e wall. These la tte r p apers have ap p a ren tly n o t been available to P rof. Frey-W yssling since his citations of m y p apers cease in 1939. In th e pap er fro m w hich he quotes, how ever, I m ade th e first suggestion, la te r applied also to th e conifer trac h eid 3, th a t certain optical properties are to be explained in term s of th e angular dispersion o f th e cellulose m a trix . In cross-section th e walls o f some of th e cells referred to (vessels of some ringporous trees) show optical discontinuities, a n d con cerning th e explanation of th is fac t I rem arked : M ay 23 , 1942, V ol. 149 “ . . . th e observed phenom ena m ay be accounted for eith er b y a v ariatio n in chain direction from layer to layer, b y a v ariatio n in chem ical n atu re , by ‘a change in th e dispersion of a single d irection’, b y a v aria tio n in th e am o u n t of cellulose p resen t in th e crystalline phase, etc. A ny one of these possible causes ‘m ay be accepted only w hen th e others have been ru led o u t’.” T he sections q uoted b y Prof. Frey-W yssling (enclosed in single in v erted commas) are therefore m isleading. T he full q uotation, an d even m ore strongly th e sense of th e whole paper, m akes it ab u n d a n tly clear th a t here I am questioning n o t th e existence of dispersion or even of changes in dispersion b u t w hether these can explain th e phenom ena u n d er review. In fact th e purpose of this p arag rap h was to em phasize w h at I have repeatedly said elsewhere— th a t th e angular dispersion of th e cellulose in a w all should n o t be overlooked in s tu d y ing its optical properties. In several places 6 I h av e directed atte n tio n to th e dangers involved in th e in te rp re tatio n of optical properties, an d p articu larly of ex tinction directions, w hen u n su p p o rted bDy u oth an d it comes p e r er i e k evidence . therefore as a surprise to find m yself indicted for failing to observe m y own precepts. On th e other han d , w hile it is clear th a t th e cellulose of m ost, if n o t all, cell ty p es is to be th o u g h t of as ‘dispersed’ ra th e r th a n ‘p arallel’ in th e stric t sense, it seems to m e a n a tu ra l an d legitim ate sim plification, in m aking prelim inary calculations such as I h av e presented, to ta k e th e ex tin ctio n direction of a wall of th e ‘dispersed’ ty p e as a h y p o th etical unique ‘cellulose chain d irectio n ’. I n m ost cases th e modifications to be expected in ad d in g th e dispersion around th e extin ctio n direction to th e resulting figures are of secondary im portance only, an d m ay be considered a t a la te r d ate as th e o p p o rtu n ity an d necessity arise. A d m ittedly, th ere are some cases where th is assum ption can n o t safely b e m ade— cases where th e dispersion itself is of v ita l im portance—a n d one of these I propose to exam ine elsewhere in th e n ear futu re, b u t generally in geom etrical considerations of grow th problem s w here I have used th is sim plifica tio n I m a in ta in th a t it is fully justified. W ith th e sta te m e n t of Prof. F rey-W yssling th a t th e dispersion can be m easured m ost readily from th e X -ra y pho to g rap h I am , of course, in com plete agreem ent. I m yself have h ith e rto used no m ethod o th er th a n th is, b u t of th e available indirect m ethods I w ould prefer th e fluorescence stain in g m ethod of M orey 7 to th e chlorzinc iodide m eth o d of FreyW yssling since th e la tte r technique introduces possible changes in dispersion on swelling. I w ould like, how ever, to p o in t o u t fu rth e r th a t Prof. Frey-W yssling is in error w hen he im plies th a t no X -ray photographs are available of single cell walls. A pho to g rap h has alread y been published of th e X -ray diagram of an oak vessel 5 an d of w h at corresponds to single walls of a conifer trach eid , an d in each of these p h o to graphs th e an g u lar dispersion can be m easured ap proxim ately. U n d er some conditions, m oreover, th e dispersion can be detected an d m easured in some cell types even th o u g h bundles of cells ra th e r th a n individual walls are p h otographed1. T here is, therefore, no fu n d am en tal difference betw een P rof. Frey-W yssling’s a ttitu d e a n d m ine concerning th e ‘dispersed’ te x tu re. T he ‘reticu lar’ te x tu re figured so often b y Frey-W yssling is, however, of a som ew hat different ty p e an d I m u st confess som e h esitatio n in accepting th is as a possibility as it stan d s. T h a t th ere occurs in latex vessels an d in No. 3786, M a y 23 , 1942 NATURE 581 m ost cells w ith p rim a ry walls a high degree o f d is persion is well established, b u t th is b y no m eans suggests th a t th e cellulose com plex is reticular. R. D. P reston. D ep artm en t of B otany, U niversity o f Leeds. A pril 22. 1 F r e y - W y s s li n g , A ., N a t u r e , 149, 3 8 4 (1 9 4 2 ). ' K u n d u , B . C ., a n d P r e s to n , R . D ., P roc. R o y . S o c., B , 128, 214 (1940); P r e s to n , l i . D ., a n d A llso p p , A ., B io d y n a m ic a , N o. 53 (1939); P re s to n , R . D ., Proc. R o y . S o c., B , 130, 103 (1941). * P re s to n , 11. D ., P roc. Leerls P h il. So c., S ei. S e c ., 3 , 546 (1939). * M a ju m d a r, G. P ., a n d P r e s to n , R . D ., P roc. R o y . Soc., B , 130, 201 (1 9 4 1 ). * P re s to n , R . D ., A n n . B o t., N .S ., 3, 507 (1939). * P re s to n , R D ., P roc. R o y . Soc., B , 125, 372 (1 9 3 8 ); P h il. T ra n s ., B , 224, 131 (1 9 3 4 ): B io l. R e e s., 14, 281 (1939). P r e s to n , R . D ., a n d A s tb u ry , W . T ., Proc. R o y . S o c., B , 122, 76 (1937). ’ M o rey , D . R ., T e x t R e s., 4, I I (1934). Effect of Certain Chemotherapeutic Agents on Experimental Eye Lesions produced by Staphylococcus aureus The difficulty of p roducing uniform staphylococca* lesions of th e cornea in th e ra b b it, for th e purpose of estim ating th e value o f th e ra p eu tic m easures, has long been recognized1 although Brow n an d P u g h 3 succeeded in producing a fairly satisfacto ry ulcer by using a strain found a fte r m a n y trials. I n th e following experim ents eight coagulase positive strain s of Staphylococcus aureus, obtained from h um an lesions, w ere trie d in prelim inary te sts on ra b b its ’ eyes, an d th e one found to be th e m ost virulent was used as it consistently produced a lesion. The lesions, how ever, were too ac u te a n d rapidly d estructive w hen an u n d ilu ted cu ltu re was injected into th e cornea, an d therefore, a fte r a n um ber of prelim inary trials, th e following technique was evolved. A 24-hour cu ltu re in b ro th w as dilu ted w ith saline to contain 1,500 organism s p e r c.c., a n d th is was injected in to th e cornea to m ake a sm all bleb u n d er th e epithelium . I n each ra b b it b o th eyes w ere so injected, an d g rea t care w as ta k e n to m ake these initial inoculations as equal as possible. I n each anim al one eye w as tre a te d w ith th e ap p ro p riate chem otherapeutic agent, w hile th e other eye was sim ilarly tre a te d w ith saline. T he first tre a tm e n t w as applied one h o u r afte r inoculation, an d th e tre a tm e n t w as usually continued a t hourly intervals for th e n e x t forty -eig h t hours, an d th ereafter a t less fre q u en t intervals. Lesions involving ulceration of th e cornea in v a ri ab ly developed in th e control eyes, a n d in 90 p er cent o f cases th is w as associated w ith developm ent of hypopyon. I n some 75 p er cent of cases th e ulcers were large an d resulted in eith er extensive corneal scarring or gross d estruction of th e eye w ith or w ith out p erforation. The lesions developed rap id ly a n d b y th e end of forty-eight hours afte r inoculation th e ulcers w ere already, as a rule, m oderately severe a n d associated w ith h ypopyon an d considerable iritis. T he following chem otherapeutic p rep aratio n s were used : (1) sodium sulphacetam ide (this w as supplied to us as a 30 p e r ce n t solution, a n d w as u sed either u ndiluted or d ilu ted w ith saline to a 10 p e r cent or a 2-5 p er cent so lu tio n ); (2) a 15 p er ce n t solution of solubilized sulphathiazole (sulphathiazole sodium form aldehyde su lp h o x y la te ); an d (3) solutions con taining penicillin, prep ared b y ex tra ctin g from fluid cu ltu re w ith am yl ac e ta te an d re-ex tractin g in to w ater, as described b y F lorey et a l.3. W hen assayed b y th e m ethods described b y these a u th o rs th e solu tio n p roduced a n are a of bacteriostasis 21-23 m m . in d iam eter, w hen te ste d ag ain st Staphylococcus aureus. T he resu lts o b tain ed w ith these p rep aratio n s are show n in th e accom panying tab le. Penicillin p ro v ed E f f e c t s o f V a r io u s T r e a t m e n t s o n E x p e r im e n t a l S t a p h y l o c o c c a l L e s io n s T h e m a in s u b d iv is io n h a s b e e n d ra w n b e tw e e n s lig h t a n d m o d e r a te , s in ce t h e ‘s lig h t’ le sio n s le f t sc a rs w h ic h w e re s m a ll a n d lo c alized a n d w o u ld n o t h a v e s e rio u s ly in te r f e r e d w ith v isio n , w h e re a s t h e ‘m o d e r a te ’, a n d o f co u rse th e m o re se v e re le sio n s, p ro d u c e d s c a rrin g w h ic h w a s c o n s id e ra b ly m o re e x te n s iv e , a n d w h ic h w o u ld h a v e s e rio u sly in t e r f e r e d w ith th e fu n c tio n o f th e ey e . T h e v e r y se v e re le sio n s in v o lv e d g ro ss d e s tr u c tio n o f t h e e y e . T h e fig u res r e p r e s e n t th e p e rc e n ta g e o f e y e s, in a n y o n e g ro u p , sh o w in g t h e p a r tic u la r ty p e o f le sio n . 582 NATURE M ay 23, 1942, V ol. 149 over, th a t th e p ro d u cts of synthesis as well as th e in itial p ro d u cts of decom position m ay be utilized by th e h o st an im al3.4-5.6. I n conform ance w ith th is opinion is th e fa c t th a t v ery few iodophile m icro organism s are found in th e fe c e s3.6. I t can be d em on s tra te d th a t several agents m ay be concerned in th e ir elim ination. T hus in vitro experim ents on centrifuged suspensions of iodophile m icro-organism s from th e ru m en o f c a ttle h av e show n th a t th e y are n o t acted upon b y p ep tic an d only slowly affected b y com m ercial try p tic p rep aratio n s. O bservations, how ever, on fresh ru m en co n ten ts dem o n strated th a t th e y are ingested an d digested in large num bers by th e ciliates p resen t (Ophryoscolecidw a n d Isotrichidse), th u s confirming W estp h al’s results w ith in vitro cultures o f rum en p ro to zo a7. I t was found, m oreover, th a t th e ciliates, unlike th e iodophile m icro-organism s, were readily ac te d upon b y enzym e prep aratio n s. Sim ilarly, exam ination of post-m ortem m a terial show ed th a t in th e abom asum th e m a jo rity o f th e ru m en P ro to zo a h a d been digested (cow an d sheep). In th e c s c u m of th e horse a digestion of b acteria b y ciliates (Cycloposthidae, Paraisotriehidai, Butschilidse, etc.) h ad also been recorded6. In th e guinea pig, how ever, th e E n to d in io m o rp h a are n o t represented an d th e sm all flagellates p resen t (Hexam ita, T richom onas, etc.) do n o t p lay an im p o rta n t p a r t in th e rem oval of b a c te ria 5. F inally, in th e a d u lt ra b b it, P ro to zo a m ay be altogether a b se n t4. I n these cases o th er agencies m u st be invoked to acco u n t for th e observed elim ination of iodophile m icro-organism s. An intensive action of digestive enzym es is precluded b y th e position of th e cajcum and colon. I t h ad been conjectured, therefore, th a t in these conditions b acterial autolysis m ig h t play an im p o rta n t p a r t6. T his hypothesis has now been te ste d as follows : Caical co n ten ts of a guinea pig were rem oved and a p o rtio n suspended in 10 per cent form alin (control). T he rem aining p o rtio n w as d ilu ted w ith saline sa tu ra te d w ith chloroform an d divided in to tw o fractions. One of these was h eated to 100 ° C. for 2 m in. B oth were in cu b ated a t 37° C. for 12 h r. ‘ M cD o n ald , R ., a n d T e t t i t , H ., A r c h . O p kth a l., 21, 817 (1939). T he form alized control show ed an a b u n d a n t d is ’ B ro w n , A . 1 ., a n d P u g h , J . , A r c h . O phthal., 16, 476 (1930). in teg ratio n of starch grains w hich were entirely * F lo re y , I I . W „ et a l., L a n cet, ii, 177 (1941). surro u n d ed b y iodophile m icro-organism s. In th e boiled fractio n th e iodine reaction of th e iodophile m icro-organism s was unchanged, w hereas in th e unboiled fractio n it h a d en tirely disappeared. Since Microbial Synthesis and Autolysis in the th e reaction of th e grains w as unim paired th e absence Digestive Tract of Herbivora o f free am ylase could be inferred. T he changes B o t h th e rum en in ru m in a n t an d th e caicum in w itnessed were, therefore, a ttrib u te d to autolysis. n o n-rum inant H erb iv o ra su p p o rt an a b u n d a n t iodo- Id en tical results w ere o btained in parallel experi phile m icroflora : th a t is, an association of taxonom - m en ts perform ed w ith ru m en co n ten ts of cattle. ically diverse species exhibiting, in consequence of I t is clear, therefore : th e deposition w ith in th em of bacterial sta rc h or (a) T h a t several agencies m ay co-operate to a granulose, th e com m on characteristic of giving a v ary in g degree in different H erb iv o ra in th e elim ina blue reaction w ith iodine. tio n o f th e iodophile m icro-organism s, nam ely : I h av e established b y d irect m icroscopic observa ( 1 ) Ingestion an d digestion b y Protozoa. tio n th a t th e iodophile m icro-organism s m ake th e ir (2) A ction of digestive enzymes. appearance on th e adoption b y th e young anim al of (3) B acterial autolysis. a vegetable diet, progressively displacing th e aniodo(b ) T h a t th e m ode of elim ination in ru m in an ts is phile species prev alen t in th e early phases of m ilk- m ore com plex th a n in non-rum inants. feeding ; and, fu rtherm ore, th a t th e y p lay a d e te r (c) T h a t in th e sim plest instance elim ination m ay m in a n t role in th e decom position of sta rc h , pectins be effected b y b acterial autolysis alone. W an d cellulose 1.2.3. A ny effort, therefore, to elucidate th e complex T hus th e decom position of these substances in th e problem s concerned in th e effective u tilizatio n of a rum en or caecum is accom panied by th e deposition p articu la r d iet m u st in ev itab ly ta k e account of th e w ithin th e m icro-organism s of an iodophile p o ly in te ra d ju stm e n t of th e processes enum erated, th a t is, saccharide. T he opinion has been advanced, m o re of th e actu al m ode of transference of th e available to be th e m ost effective in th e tre a tm e n t of these staphylococcal lesions. I t is probable th a t still b e tte r results will be produced w ith m ore concentrated solu tions of penicillin. T he resu lt in one anim al (494) is illu strated in th e accom panying figure. Sodium sulphacetam ide (30 p er cent) produced q u ite obvious beneficial effects. Because of its know n value again st staphylococci, we expected very satisfacto ry results w ith th e con c e n trated solution of sulphathiazole, b u t th e y were u n fo rtu n ately disappointing. W eaker concentrations of sodium sulphacetam ide were tried in sm all groups of anim als. T he results suggest th a t a 10 per cent solution m ay perhaps be as effective as th e 30 p er cent solution, b u t th e 2-5 per cent solution produced only slight benefit in th e tre a tm e n t of these lesions. T he prelim inary reports of F lo re y et. a l.* have already suggested th a t penicillin m ay be effective in th e tre a tm e n t of eye lesions. O ur experim ental results su p port th is conclusion, an d also offer evidence th a t sodium sulphacetam ide m ay be of value in th e local tre a tm e n t of staphylococcal lesions of th e hum an eye. W e should like to th a n k D r. Oag, of th e D e p a rt m en t of Bacteriology, U niversity of E dinburgh, for his advice an d for supplying th e cultures an d dilu tions used in these experim ents. Mrs. M acN aughtan, of th e D ep artm en t of Bacteriology, U niversity of E dinburgh, very k indly supplied us w ith penicillin solution. W e are indebted to D r. P re sc o tt of B u r roughs, W ellcome an d Co. for th e p rep a ra tio n of the solubilized sulphathiazole an d to Mr. E dw ards of B ritish Schering, L td ., for th e supply of sodium sulphacetam ide (albucid soluble). We are g rateful to th e W . H . Ross F o u n d atio n (Scotland) for th e S tu d y an d P revention of Blindness, w hich defrayed th e expenses of th is investigation. J . M. R o b s o n . D ept, of Pharm acology, S c o tt. U niversity of E d inburgh. M ay 4. No. 3786, M ay 23, 1942 NATURE polysaccharides from th e vegetable m aterials ingested to th e tissues of th e anim al. No m ention h as been m ade in th is com m unication o f th e p rotein syntheses integral to th e m aintenance of a m icrobial population in th e crecum or rum en ; n o r of th e initial nitrogen sources from w hich th e y m ay lie able to proceed. A detailed stu d y of some m icrobiological aspects of th e problem is, however, now being m ade in close collaboration w ith th e biochem ical investigation of in vitro incubations of rum en contents in progress a t th e H an n ah D airy R esearch I n s titu te 3-8. F b a n k B a k er . D ep artm en t of Biology, County Technical College, Stoke P ark , Guildford. April 27. 1 B a k e r, F ., a n d M a rtin , E ., N a t u r e , 141, 877 (1938). * B a k e r, I1'., S c i. Prog., N o . 134 (O c t., 1939). 1 B a k e r, F ., N a t u r e , 149, 220 (1942). 1 B a k e r, F ., a n d M a rtin , 11., Z e n t. B a ld ., A b . I I , 96, 18 (1937). * B a k e r, F ., a n d M a r tin , K ., Z e n t. B a k t., A b. I I , 97, 201 (1937). * B a k e r, I ’., a n d M a rtin , E,., Z e n t. B a h t., A b . I I , 99, 400 (1939). 7 W e stp lia l, A ., Z en t. P a r a s ite n k ., 7, 71 (1934). * O w en, E . C ., S m ith , J . A . B ., a n d W rig h t, N . C ., N a t u r e , 147, 710 (1941). Spore Dispersal in the Mucorales problem of spore dispersal presented in m y last com m unication 1 is now p artially solved, as a resu lt of spore-blowing experim ents a n d th e observa tion of cultures grow n in cem ented glass cells w ith coverslip surfaces. T he chief fact w hich em erges is th a t th e M ucor sporangium is prim arily a w ater dispersal m echanism , an d th a t M ucor spores, for th e m ost p a rt, becom e a ir borne only afte r prelim inary separation in w ater, and th en chiefly on th e surface of soil d u st particles and h y p h al fragm ents. T he sporangial m em brane in M ucors breaks up an d eventually disappears in co n tac t w ith w ater. In Mucors w ith th in walls, usually described as ‘diffluent’ (for exam ple, M . liiemalis), this process is rapid, and if th e sporangium rem ains untouched in m oist air it gives place to a conspicuous sporangial drop. The stalk on losing tu rg id ity collapses a n d usually brings th e drop against a solid surface, w hereupon it spreads o u t rap idly owing to surface tension. T he w ord ‘b u rs t’ is in ap p ropriate to describe th is process. On drying dow n th e spore m asses rem ain firm ly stu c k tog eth er w ith m ucilage which, however, is readily dissolved an d th e spores separated in w ater. Growing on organic m a tte r in soil th e sporangiophores can be seen to form a netw ork linking th e soil particles, against w hich th e sporangia are inevitably bro u g h t into co n tact a t some stage, w ith th e p re sum ed resu lt th a t th e spores a re dispersed b y th e soil w ater w hen present. Spore-blowing experim ents on th is ty p e of Mucor show th em to be com plete spore retainers in air. T he function of th e sporangiophore is th u s seen to be th a t of ensuring some prelim inary dispersal of th e spore masses, ra th e r th a n th a t of raising th e sporangium into th e air. I ts sensitiveness to light in th e early stages of grow th m ay also have th e effect of co u n terac t ing th e down-washing of w ater, a n d raising th e spore masses so as to keep th em in th e u pper layers of th e soil, w here b o th aeration an d organic m a tte r provide more favourable conditions for th e grow th o f Mucors. H ow ever, w hen air-dried soil, w hich has been T he sterilized an d th e n soaked in a suspension of spores of M ucor hiemalis, is su b jected to gentle blowing, m any colonies are o btained, som e of w hich arise from visibly single spores, b u t th e m a jo rity from soil particles, a n d n a tu ra l soils also yield sc attered col onies of diffluent-w alled M ucors. T he occurrence of air-borne infections b y M ucors of th is ty p o is th u s explained, a n d also th e ir freq u en t presence in d ust. Some species, however, n o ta b ly M . rouxianus, exhibit a subsidiary form of air dispersal, in th a t th e old d ry m ycelial n etw o rk is extrem ely b rittle, an d when blow n upon fragm ents, yielding sc attered colonies each of w hich is found to arise from a spore m ass, or even a single spore, a tta c h e d to a hyp h al fragm ent. T his is referred to as hyphal spore dispersal. M ucor racemosus also fragm ents in th is w ay, d is persing chlam ydospores as well as a tta c h e d sporangiospores. A few spore m asses, w ith o u t hyphaj, are also dispersed, an d th e stalk s do n o t collapse so com pletely, so th a t some direct air dispersal is possible. H ere th e wall survives longer in co n tact w ith w ater, an d th e spores h av e been seen to pass o u t in to a superficial drop. The sporangial drops are less conspicuous, as surviving pieces of w all m ay render th em relatively opaque. P ro b a b ly m ost of th e M ucors w ith th ick (‘frag m en tin g ’) walls are of th is ty p e, w hich rem ains chiefly w ater-dispersed. A bsidia glauca is a spore-mass-shudder w ith re la tively little h y p h al dispersal. D espite such a d a p ta tions to air dispersal as stoloniferous grow th, rigid sporangiophores, an d a colum ella w hich collapses into a cup, liberating th e w hole spore m ass, i t form s sporangial drops, scatters no single spores in air, an d seems to be readily w ater-dispersed. I t is th u s in te r m ed iate in ty p e. Rhizopus nigricans, however, exhibits advanced a d a p ta tio n to air dispersal. T he sporangiophores, b orne alo ft on ‘stolons’ a n d firm ly ‘ro o ted ’ on th eir su b strate, rem ain rigid w hen dry, an d th e collapse of th e colum ella in to a bell-shaped cap exposes th e spores to air m ovem ents for long periods. Such sporangiophores, grow n in a glass cell in 1939, are still erect an d capable of shedding viable spores afte r th ree years. T he rough ang u lar spores are n o t easily w etted, an d do n o t ‘clum p’ closely in w ater, so th a t th e y d ry o u t rapidly, an d are n o t stu c k to g eth er in m ucilage. This type, how ever, sheds no spores w hen m oist, b u t b ro ad casts spore m asses of v ary in g size, an d single spores, w hen q u ite d ry. I t is therefore called a dried-spore-shedder. F inally, in conidial ty p es such as Cunningham ella we h av e spore shedders w hich sc a tte r spore m asses from th e fresh, m oist colony, an d v a s t n u m b ers of single spores from th e d ry , an d are com parable in efficiency of air dispersal w ith m a n y H yphom ycetes. The M ucorales are th u s b ro u g h t in to closer rela tionship w ith th e o th er groups from w hich th e y have been som ew hat isolated. Once it is realized th a t th e Mucor sporangium is a w ater-dispersal m echanism , it can b ear some com parison w ith th a t of th e soil O om ycetes, especially in th o se species w hich liberate akinetes, an d a t th e sam e tim e th e various conidial forms, some of th em approaching those of th e Plectom ycetes, become intelligible as a d a p ta tio n s to air dispersal. C. G. D o b b s . B o tan y D ep artm en t, K in g ’s College, London, a t T he U niversity, B ristol 8 . A pril 4. ‘ N a t u r e , 143, 2 8 6 (1 9 3 9 ). NATURE 584 M ay 23, 1942, v o l. 149 SEA W AVES: THEIR GROWTH AND SUBSIDENCE By P. J H. U N N A H E effect of tid al stream s on swell w as discussed in N a t u r e of F eb ru ary 21, p. 219, th e standard for com parison being th e slack-w ater sta te . E stim ates depended on th e fac t th a t, in swell, w aves re ta in th eir identities as individuals. B u t w ind-forced waves cannot do so, even w hen th ere is no change in stream , because, w ith speed proportional to ro o t of length, th eir periods lengthen as th e y grow—see below— an d in so fa r as this affects th e issue th e argum ents for swell m ay n o t hold good. B u t stream , m ore efficiently as th e w aves lengthen, an d so, except tid al or otherwise, can also influence ra te of grow th, a t q u ite an early stage, b y pressure ra th e r th a n by for w hich no slack-w ater sta n d a rd is available, th e friction, th e area of application of th e pressure speed ing up as th e waves m ove faster. L ater, well beyond laws of grow th being still unknow n. I t is therefore th e lim it of Stevenson’s equations, dim inution in necessary to im provise. I t seems th a t an y system of w ind-forced waves steepness an d in relativ e speed o f w ind an d waves consists of a t least th ree series : th e p rim ary a n d m ost will cause th e pressure to g et less, an d d Pj dF to do conspicuous waves, th e sm aller secondary ones w hich th e same. T he figures for tim e show how long th e w ind has ride upon them , an d th e long low w aves1’2, m ore akin to swell, th a t are m asked b y th e prim aries. I t to blow before th e sea a tta in s a stead y m axim um for m ay be assum ed th a t, u n d er stabilized conditions, a given fetch. T hey are based on th e speed of th e energy of th e prim aries. stead y w ind of given stren g th gives rise to p rim ary E L , th e to ta l energy of a w ave, p er foot of crest, waves of given average length an d height, according ten d s to con cen trate n ear th e crest ju s t before b reak to fetch an d to stre n g th a n d direction, or absence, of stream . B u t th e only d a ta available are tw o inde ing, an d should therefore be an index of strik in g force ag ain st a breakw ater. Values are given for p en d en t sets of observations, w hich, w hen com bined, give figures for p rim ary w aves due to th e strongest d( EL) jdF to show how, w ith stead y wind, an ex tra w inds ordinarily m e t w ith. These figures are m erely mile added to a long fetch increases m axim um strik in g force m uch m ore th a n w hen added to a sh o rt te n tativ e, b u t suffice to show th e general tren d , and one. T h ey are based on th e derived expressions, to illu strate th e principles involved. F irst, th e re are Stevenson’s eq uations3, intended (6O H 3 + 4- 8H3 + 16L H ) (0-75F - i - 0 -2 5 ZM) for to give g rea test w ave height according to fetch : sh o rt fetches, Hmax. = l ' 5 F i + 2-5 — F i for fetches from 1 to (6O H 2 + 4-8H 3 + 16L H ) x 1 -125/7-1 for longer 39 miles, fetches. H max. = 1 -5Fi for fetches from 40 to 120 miles, Owing to lengthening of period, w hen waves in F being fetch in miles. Secondly, ta k in g W ilto n ’s 4 crease in len g th from L t to L 2, one w ave in every theoretical lim it of 0-13 for steepness as applicable y/L-i -7- (\/-^ 2 — ’S /Fj) has to disappear. In other to new -born waves, th e m ore reliable recorded m easurem ents, including m an y of those sum m arized words, one w ave m every 2 Lr .dF — -f 1 vanishes m dL b y G aillard5, indicate th a t for w ave-lengths u p to each m ile of fetch. The figures given for percentage 400 ft. th e g rea test steepness ordinarily m et w ith in loss show th a t th e waves become m ore p erm an en t th e open m ay be expressed as : w ith g reater fetch, an d presum ably th e y th en behave Smax. = (7-5 + 0-3 H ) ~\ m ore like swell w ith change of stream . However, th a t is, L — 7*5//rrwx. 0 * • } ( / Imax.)2' it is w ith these longer w aves th a t stream has least There is no guaran tee th a t all th e m easurem ents effect on swell. on w hich these equations are based relate to slack B u t stream m ay h av e consequences w hich do n o t w ater, as will be assum ed here. A nd th e equations will arise w ith swell, for n o t only m ay it affect ra te of be ta k en as th e histo ry of grow th of a definite w ave grow th, b u t also it m a y a lte r effective fetch. F or system u nder stead y wind, although th e strongest exam ple, w hen th e re is a local w ind in th e open, and w inds over sh o rt fetches are unlikely to persist over so n o t blowing off a w eath er shore, speed over th e long ones. T he following equations resu lt : ground becomes irrelev an t, an d y e t stream m ay m odify th e fetch. T ravel of th e centre of a cyclonic dP — = QH(2-5Li + 0-15L -iH -) (0-75F -i - 0-25F-i) distu rb an ce is an analogous case. I t increases fetch iij one semicircle, b y m ere coincidence th e one called up to 39 miles, ‘dangerous’ for q u ite a different reason, an d reduces dP — = 25L i 4 - 1-5L - i H 2 from 40 to 120 miles, it in th e o th e r6. T he speed of th e cen tre in relation dF to th a t of th e w ave energy is th e relev an t factor. P (— E G ) being power, th a t is, energy jjer sq. ft. of Consideration of th e effect of stream on ra te of w ater surface m ultiplied b y its speed to leeward. grow th raises th e ra th e r puzzling problem of th e The resulting values are as in th e tab le below. hairp in bend. A riv er tak es a hairpin bend, and The figures for dP jd F only relate to pow er th e w ind blows u p one reach. A lternatively, it m ay effectively used in raising th e p rim ary waves. More be blow ing u p an arm of th e sea w ith a narrow is required for th e other series, viscosity, turbulence, entrance, up th e Solent from H u rs t would be a case breaking, an d to give leew ay to th e w ate r n ear the in point. Given, say, a 3-knot w eather-going stream , surface. N evertheless, th ey indicate th a t th e w ind acts th e waves will fail to stem th e tid e u n til th ey a tta in T No. 3786, M ay 23, 1942 NATURE a 5-ffc. length, and th e ir energy will fail to do so until they become 20 ft. long. P resum ably waves do form near th e w eather shore w hen it s ta rts to blow, b u t it looks as if th e y m u st be soon dispersed b y breaking. The solution m ay be th a t those w hich form to lee w ard, an d so in th eir early life are independent of speed over th e ground, a tta in th e lengths necessary for survival before th e y are sw ept back to th e w eather shore. I n th a t case th e re should be w aves of ap p re ciable length w here th e re is alm ost inappreciable fetch, afte r th e w ind has been blow ing long enough for th e conditions to be stabilized. I t w ould be interesting to know w h at actually does happen. B u t assum ing th a t a stab le regim e has been a t tained, it is possible to roughly estim ate th e change in th e dem and for w ind energy, an d so th e surplus available for increasing th e sea, th a t a w eather-going stream entails. W ave pow er over th e ground is E(G -j- C), G being stream in ft./sec., an d negative for w eather going. L et E 1G1 ap p ly to a given position, an d _Z?j(r2 to an o th er position a mile to leew ard. The increase in w ave pow er w ithin th a t distance, th a t is, over a strip of w ate r a m ile long an d a foot wide, will be E 2G2 — E 1Gl in slack w ater, an d E 2G2 — E 1G1 -f C (E t — E ,) w ith strea m C. T h a t w ould only be stric tly correct if th e w ind could be so ad ju sted th a t E 2 an d G2 m ight retain th e ir slack-w ater values. Then G(E2 — E j) w ould be th e change w hich G entails in th e dem and for power, b u t it m ay also be tak en as a rough estim ate of th e surplus available for increasing th e sea w hen th e strea m has m ade to th e w eather w ith o u t change in wind, a su r plus additional to an y due to greater speed of w ind over w ater. To p u t th is in an o th er w ay, d(EG) T dH. ■~~jj? = 16HG.-^j-p = 18(7 ft.-lb. p e r sq. ft. p er sec. p er mile, for Stevenson’s highest w aves w ith long fetches. The corresponding expression for short fetches would be (18 + 347'' ! — IS i'H — 10F-i)C, giving 24C, 19C, 17-5(7, 16-80, 16-3C, 16C, 15-80 for th e fetches in th e table. To ta k e an exam ple, th e value of 18C for a 3-knot stream is 90, a co n stan t stirplus for w eather going, an d deficiency for lee going, stream com prised in th e increasing slack w ater figures for dP /d F for th e longer fetches in th e tab le. T hus, as w ith swell, stream seems to have less prop o rtio n ate effect on longer waves ; and from th e w ay in w hich th e sea steepens w hen th e stream tu rn s to th e w eather, i t looks as if th e surplus is used in heightening ra th e r th a n in lengthening them , an d so in intensifying ra th e r th a n in speeding up th eir energy. B u t th is line of reason ing for th e case in w hich a w eather shore has to be tak en into account has obvious defects, an d it is only p u t forw ard in th e hope th a t someone m ay be able to explain w h at really happens. Now as to subsidence. T he ra te a t w hich swell subsides owing to th e viscosity of th e w ater can scarcely be m easured, b u t i t has been calculated by Stokes7, who, tak in g as exam ples waves 2 in. an d 240 ft. long, has show n th a t it is m uch slower for th e longer waves. U nfortunately, his form ula gives th e daily loss in height for th e 240-ft. w aves as only } p er cent, an d th is seems m uch too sm all. In fact, a steepisli swell only 100 ft. long should subside into an alm ost flat calm afte r a couple of days, w hereas by form ula it w ould only lose a te n th of its height a week. T he p ro b ab ility is th a t other effects p re p onderate. T hus a sh o rt sea is generally local, and always so in narrow w aters. T herefore th e ta il of its energy will soon pass on, an d leave a calm behind. 585 A gain, waves lose height because th e ir energy only trav els h a lf as fast as th e y do, a n d th e sh o rter waves will lose heig h t m ore quickly on th is account. Com p are tw o h y p o th etical swells, w ith 6,000 waves, 400 ft. a n d 100 ft. in length. T hey will cover 400 an d 100 m iles to s ta rt w ith. T he m iddle waves of each will s ta r t to lose height, for th e reason m en tioned, w hen th e y h av e trav elled th ro u g h these distances, th a t is, afte r 15 an d 7|- hours, as th e case m ay be. T he m odulus of viscosity is based on frictional action betw een layers shearing one over th e other. On th e o th er han d , w ater m ovem ent u n d er w ave action involves tw o-dim ensional distortion, w h at were elem entary cubes in calm being d isto rted , approxim ately, from u p rig h t to h o rizontal oblongs, cubical form being passed m idw ay. I f th e w ork done ag ain st viscosity w ere p ro portional to th e linear d isto rtio n o f th e cubes, th e loss in w ave heig h t p er second w ould be absolute, an d n o t a percentage one, an d p ro portional to L -i, w hile th e d istance th ro u g h w hich th e w aves w ould h av e to trav e l before th e y com pletely flatten down w ould be p ro p o rtio n al to L U , T h a t seems m ore in accordance w ith ordinary experience. P erh ap s an ac tu al exam ple will be m ore convincing. T he period of th e s u rf on th e G uinea Coast, 10-12 sec., is ab o u t double th e o rd in ary period of w aves in th e S traits of D over. T he su rf p ro b ab ly originates in energy th a t has trav elled from th e S outhern Ocean, a jo u rn ey of a t least a week, w hile hours ra th e r th a n days w ould be th e m easure of th e tim e of calm ing in th e S traits. B u t to re tu rn to th e original question o f length an d heig h t in relatio n to w ind an d fetch. D eterm in a tio n of th e em pirical laws should go some w ay to w ards solving th e problem s th a t su rro u n d windforced waves. M easurem ents ta k e n a t lee shores w ith various b u t preferably sm all exposures, during stead y w inds of various strengths, m ig h t give some clues, an d th e y could easily be m ade w'here th e con ditions are suitable. I n a n y event, w aves affect so m an y things, ships— b reakw aters, erosion an d litto ral d rift—th a t fu rth e r know ledge as to th e ir behaviour can scarcely fail to p ay . 1 V a u g h a u C o rn ish , “ W a v e s o f th e B oa” , 87. 2 J e ffre y s , H ., Proc. R o y . S o c ., A , 107, 189. 3 S te v e n so n , T h o m a s , “ T h e D e sig n a n d C o n s tru c tio n o f H a r b o u r s ” 2 n d e d ., 2 2 -2 6 . 4 P h il. M a g ., (6) 23, 1055 (1913). 6 G a illa rd , “ W a v e A c tio n ” , 32, 76. 6 See also V a u g h a n C o rn is h , “ W a v e s o f t h e S ea” , 121. 7 S to k es, “ M a th , a n d P h y s . P a p e r s ” , 3, 42 (w ith f o o tn o te ). N EW SEISMOGRAPH STATION AT LOGAN, UTAH H E in stallatio n of a seism ograph a t U ta h S tate A gricultural College was m ade possible th ro u g h a g ift from th e estate of fhe late T hom as E . O ldham , an E nglish-born resid en t of Logan, who died in 1938 (“The O ldham Seism ograph sta tio n a t U tah S ta te A gricultural College, Logan, U ta h ” , b y J . S tew art W illiam s, B ull. Seis. Soc. A m er., 32, No. 1, Ja n u a ry , 1942). T he nam e is a v ery h ap p y one in view of th e histo ry o f seismology, th o u g h th e late T hom as E . O ldham of U ta h b ea rs no know n relatio n sh ip to T hom as O ldham o f th e Geological S urvey of In d ia (1816-1878), an d R . D. O ldham his son (1858-1936), who first recognized th e longitudinal an d tran sv erse T 586 NATURE ch aracter of th e tw o types of prelim inary waves of a n earth q u ake. T he seism ograph room is in th e basem ent of th e m ain college building, th e approxim ate geographical location being la titu d e 41° 45' N ., longitude 111° 47' W . T he sta tio n is equipped w ith tw o horizontal com ponent W ood-A nderson seism ographs bought w ith th e gift, and an accelerograph installed b y th e U n ited S tates Coast a n d G eodetic Survey. T he seism om eters are m ounted on concrete blocks 28 cm. high, keyed into th e surface of a pier, resting in wellcem ented gravels of th e Bonneville delta, a n d s ta n d ing a t a height of 4,772-3 ft. above sea-level. I n s ta l lation of th e accelerograph was com pleted in J u ly 1939 an d th e W ood-A nderson instrum ents began operation on J a n u a ry 26, 1940. Since O ctober 1, 1940, all seism ogram s have been checked b y th e U nited S tates Coast an d G eodetic Survey, an d th e results will be published in th e m onthly seism ographic report. The n o rth -so u th seism om eter has a sta tic m agni fication of 716-8, th e east-w est seism om eter one of 697-9. T he period for b o th is m ain tain ed a t 6-0 seconds, th e dam ping ratio a t 20 : 1. T he recording drum has so far been ru n a t 15 m m ./m . T he seism o m eters are in pro tectiv e coverings w hich are also provided w ith w ater cans in an a tte m p t to elim inate tem p eratu re variations n ear th e instrum ents. The accelerograph, le n t an d m ain tain ed b y th e U nited S tates Coast a n d G eodetic Survey, is a No. M -45, w ith a 12-in. recorder, an d has th ree com ponents. T he site appears to be a p articu la rly h a p p y one, especially for th e accelerographs, since U ta h appears to be th e m ost seism ically active of th e R ocky M ountain S tates. T his la tte r m ay be rela ted to th e zone of faulting th a t m arks th e eastern m argin of th e G reat Basin. One centre of a c tiv ity has been in W ashington an d Iro n Counties, ad jac en t to th e H urrican e fault, a n d an o th er centre lies in Sevier C ounty betw een th e T u sh ar an d Sevier faults. N early one th ird of th e earth q u ak es of U ta h have occurred close to th e W asatch fault. FORTHCOMING EVENTS (M eetings m a rk ed w ith a n asterisk are open to the public) Wednesday, May 27 P h y s ic a l S o c i e t y (C o l o u r G r o u p ) (at, th e R o y a l P h o to g ra p h ic S o c ie ty , 16 P rin c c s G a te , L o n d o n , S .W .7), a t 2.30 p .m .— D iscu ssio n o n “ T h e R e la tiv e M e rits o f S p e c tr o p h o to m e try a n d C o lo rim e try ” (to b e o p en e d b y M iss D o ro th y L . T ille a rd ). I n s t it u t e o f C h e m is t r y (L o n d o n a n d S o u t h E a s t e r n C o u n t ie s S e c t i o n ) ( a t 30 R u s s e ll S q u a re , L o n d o n , W .C .l ) , a t 6 p .m .— D r. H . B ain es : “ R e c e n t A d v a n c e s in P h o to g ra p h ic T h e o ry ” . Thursday, May 28 B r i t i s h P s y c h o l o g ic a l S o c i e t y ( I n d u s t r i a l S e c t i o n ) ( a t th e N a tio n a l I n s t i t u t e o f I n d u s tr ia l P sy c h o lo g y , A ld w y ch H o u se , A ld w y c h , L o n d o n , W .C .2), a t 1.20 p .m .— M iss M ay S m ith : “ F a tig u e , a R e v isio n o f P a s t a n d S u rv e y o f P r e s e n t P ro b le m s ” . Friday, May 29 R o y a l I n s t i t u t io n o f G r e a t B r it a i n ( a t 21 A lb e m a rle S tre e t, L o n d o n , W .l ) , a t 5.15 p .m .— M r. S e to n G o r d o n : “ W ild L ife in th e W e s te rn H ig h la n d s ” .* B r i t i s h I n s t i t u t i o n o f R a d io E n g i n e e r s ( L o n d o n S e c t i o n ) ( a t t h e F e d e r a tio n o f B ritis h I n d u s tr ie s , 21 T o t h i l l S tr e e t, L o n d o n , S . W .l ) , a t 7 p .m .— M r. O . S . P u ck Je : “ T im e B a s e s ” .* INSTITUTE OF PHYSICS (MANCHESTER AND DISTRICT BRANCH) (in th e P h y sic s D e p a r tm e n t, U n iv e rs ity o f M a n c h e s te r), a t 7 p .m .— D r. J . M cG . B r u c k s h a w : “ P h y sic s in th e S e a rc h fo r O il” .* Saturday, May 30 N u t r it io n S o c i e t y ( a t th e L o n d o n S chool o f H y g ie n e a n d T ro p ic a l M edicine, K e p p e l S tre e t, L o n d o n , W .C .l). a t 1 1 a .m .— C o nference on “ P ro b le m s o f C o llectiv e F e e d in g in W a r- tim e ” . M ay 23. 1942, V o l. ms APPOINTMENTS VACANT A p p l i c a t i o n s a re in v ite d fo r th e fo llo w in g a p p o in tm e n ts o n o r b e fo re th e d a te s m e n tio n e d : M e t a l l u r g i s t fo r re s e a rc h w o rk in c o n n e x io n w ith p ro b le m s a tte n d in g co llie ry w ire ro p es a n d o th e r co a l-m in in g a p p lia n c e s — T h e C h ie f E x e c u tiv e O fficer, S a fe ty in M in es R e s e a rc h L a b o ra to rie s, P o r to b e llo S tr e e t, Sheffield 1 (M ay 29). S p e e c h T h e r a p i s t ( w o m a n ) — T h e D ire c to r o f E d u c a tio n , E d u c a tio n O ffices, W o o d la n d s R o a d , M id d le sb ro u g h (M ay 30). T e a c h e r o f M a t h e m a t ic s a n d a T e a c h e r o f P h y s ic s — T h e P rin c ip a l, S o u th -W e s t E s s e x T e c h n ic a l C ollege a n d S ch o o l o f A r t, F o r e s t R o a d , W a lth a m s to w , L o n d o n , E .1 7 ( M a y 30). L e c t u r e r i n S c i e n c e — T h e P rin c ip a l, D o m e s tic S cien ce T ra in in g C ollege, K n ig h to n F ie ld s , L e ic e s te r (M ay 31). E l e c t r ic a l E n g i n e e r a n d M a n a g e r — T h e T o w n C le rk , T o w n H a ll, S t. H e le n s, L a n c s, (en d o rsed ‘A p p o in tm e n t o f E le c tric a l E n g in e e r a n d M a n a g e r’) (J u n e 1.) S e n i o r L e c t u r e r ( m a n o r w o m a n ) in th e S c i e n c e D e p a r t m e n t o f th e C ity o f L e ed s T ra in in g C ollege, w ith sp e c ia l q u alific atio n s in B io l o g y —-The D ir e c to r o f E d u c a tio n , E d u c a tio n Offices, L eed s 1 (J u n e 1 ). C h i e f L a b o r a t o r y S t e w a r d — T h e P r i n c i p a l , T e c h n ic a l C o lle g e , D o n c a s te r. S e n i o r W o m a n L e c t u r e r i n B io l o g y — T h e P rin c ip a l, S o u th la n d s T r a in in g C ollege (L o n d o n ), a t H ig h b u r y , A tla n tic R o a d , W e sto n su p e r-M a re . M i s t r e s s t o t a k e c h a r g e o f t h e G e n e r a l S c i e n c e W o r k ------- T h e H e a d m is tre s s , D a y T e c h n ic a l S ch o o l f o r G irls, F o r t P i t t , C h a th a m . REPORTS and other PUBLICATIONS (not included in the monthly Boohs Supplement) Great Britain and Ireland S o u th -W e st E s s e x T e c h n ic a l C ollege a n d S ch o o l o f A r t. A n n u a l R e p o r t, S ession 194 0 -4 1 . P p . 23-f-4 p la te s . ( L o n d o n : S o u th -W e st E s s e x T e c h n ic a l C ollege a n d S ch o o l o f A r t, W a lth a m s to w ./ [45 P ro ceed in g s o f th e R o y a l I r is h A cad em y . V o l. 47, S ectio n A , N o. 6 : I n h e r e n t R e la tio n s b e tw e e n R a n d o m V ariab les. B y D r. R . C. G eary . P p . 6 3 -7 6 . I s . V ol. 47, S e c tio n B , N o . 13 : R . L iffey S u rv ey , 4 : T h e F a u n a o f th e S u b m erg e d “ M osses” in a n A cid a n d a n A lk alin e W a te r . B y W in ifred E . F r o s t. P p . 2 9 3 -3 6 9 + p l a t e 6. 5s. V ol. 47, S ectio n B , N o . 14 : T h e E x p lo ra tio n o f so m e C aves n e a r C astleto w n ro ch e, Co. C o rk (S tu d ie s in I r is h Q u a te rn a r y D ep o sits, N o. 4). B y A . M . G w y n n , G. F . M itc h ell a n d A . W . S telfo x . P p . 3 7 1 * 3 9 0 -I-plate 7. Is . 6d. V ol. 48, S e c tio n B, N o . 1 : T h e D is tr ib u tio n o f P h y to p la n k to n in so m e N o rth -W e s t I r is h L o u g h s. B y W . H . P e a rs a ll a n d E d n a M . L in d . P p . 24. I s . (D u b lin : H o d g es, F ig g is a n d Co., L td . ; L o n d o n : W illiam s a n d N o rg a te , L td .) [45 O ther Countries S m ith s o n ia n I n s tit u tio n : U n ite d S ta te s N a tio n a l M u seu m . B u lle tin 161 : T h e F o ra m in ife ra o f th e T ro p ic a l P a c ific C o llectio n s o f th e A lb a tro ss, 1 8 9 9 -1 9 0 0 . P a r t 3 : H e tc ro h e lic id a e a n d B u lim in id ae. B y J o s e p h A u g u stin e C u s h m a n . P p . v + 67 + 15 p la te s . (W a s h in g to n , D . C . : G o v e rn m e n t P r in tin g Office.) 20 c e n ts . [274 M in is try o f F in a n c e : S u rv e y o f E g y p t. S u rv e y P a p e r N o . 45 : M ap P ro je c tio n s in P ra c tic e . B y J . H . Cole. P p . i i i + 4 3 . ( G iz a : S u rv e y o f E g y p t.) [304 U .S . D e p a r tm e n t o f A g ric u ltu re . C irc u la r N o . 6 3 2 : R ic e -F ie ld I n s e c ts . B y W . A . D o u g las a n d «T. W . I n g r a m . P p . 32. (W a s h in g to n . D . C . : G o v e rn m e n t P r in tin g O ffice.) 10 c e n ts . [15 I n d ia n C e n tra l C o tto n C o m m itte e : T e c h n o lo g ical L a b o ra to ry . T e ch n o lo g ical B u lle tin , S eries A, N o . 53 : T e c h n o lo g ical R e p o rts o n T r a d e V a rie tie s o f I n d ia n C o tto n s, 1941. B y D r. N a z ir A h m a d . P p . v ii + 103. 1 .8 ru p e e s . T e c h n o lo g ic a l B u lle tin , S erie s A , N o . 5 4 : T e ch n o lo g ical R e p o r ts o n S ta n d a r d I n d ia n C o tto n s , 1941. B y D r. N a z ir A h m a d . P p . ii + 115. 1.8 ru p e e s . ( B o m b a y : I n d ia n C e n tra l C o tto n C o m m itte e .) [115 B u re a u o f E d u c a tio n , I n d ia . E d u c a tio n in I n d ia in 1 9 3 7 -3 8 . P p . v ii - f 109. 2.8 ru p e e s ; 4s. E d u c a tio n in I n d i a in 1 9 3 8 -3 9 . P p . vii + 138. 3 ru p e e s ; 5s. ( D e lh i: M a n a g e r o f P u b lic a tio n s .) [115 I n d ia n F o r e s t R e c o rd s (N ew S eries). B o ta n y , V ol. 3, N o . 2 : Som e A d d itio n s to th e “ B o ta n y o f B ih a r a n d O ris sa ” . B y H . F . M ooney. P p . v + 6 3 -1 2 0 . 2 r u p e e s ; 3s. B o ta n y , V ol. 3, N o . 3 : F iv e N ew I n d ia n a n d B u rm e se F lo w e rin g P la n ts — C eropegia bo rii M . B . R a iz a d a , B a u h in ia lyra ta M. B . R a iz a d a , N e p tu n ia robertsonii M . B . R a iz a d a , C a p p a ris c h a m o m sis M . B . R a iz a d a , a n d P hlogaeanthus p o c h in ii M. B . R a iz a d a . B y M . B . R a iz a d a . P p . iii + 1 2 1 -1 2 8 + 5 p la te s . 14 a n n a s ; I s . 3d. B o ta n y , V ol. 3, N o . 6 : T h e R e lic t V e g e ta tio n o f t h e S h illong P la t e a u , A esam . B y D r. N . L . B o r. P p . v 4 -1 5 2 -1 9 5 . 2.2 r u p e e s ; 3s. 6$. S ilv ic u ltu re , V ol. 4, N o . 4 : In v e s tig a tio n s in to A rtificial R e g e n e ra tio n D e ta ils o f th e D r y F u e l F o r e s ts o f M a d ra s. B y A . L . G riffith . P p . i v - f 1 6 1 -2 2 4 + 4 p la te s . 2 .8 r u p e e s ; 4 s. ( D e lh i: M an ag er o f P u b lic a tio n s .) [115 F o r e s t R e s e a rc h I n s t i t u t e , D e h r a D u n . L e a fle t N o . 6 : N o te o n so m e E x p e r im e n ts o n C o rk S u b s titu te s . B y D r. D . N a ra y a n a im irti. P p . ii-j-4 + 1 p la te . L e a lle t N o . 7 : A N ew T y p e o f V en eer D ry in g R ack. B y M . A . R e h m a n a n d S u lta n M o h a m m a d . P p . i i + 4 + 2 p la te s . (D e h ra D u n : F o r e s t R e s e a rc h I n s tit u te .) [115 H e r b e r tia . V ol. 8 : D a y lily e d itio n . E d ite d b y H a m ilto n P . T ra u b . P p . 186 (27 p la te s ). (O rlan d o , F la . : A m e ric a n A m arv llis S o ciety .) 3.25 d o lla rs . ‘ [115
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