Datasheet
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Date : 2016/4/12
Catalog Number
Product Name
GTX84003
Package:100 μl
NRBP1 antibody [6C11]
Full Name
nuclear receptor binding protein 1
Synonyms
NRBP, NRBP1, MUDPNP, BCON3, MADM
Product Description
Specificity
Background
Host
Clonality
Mouse monoclonal antibody [6C11] to NRBP1
GTX84003 is specific for human NRBP1.
May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rhotype GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular
membrane structure associated with flaviviral replication.
Mouse
Monoclonal
Clone Name
6C11
Isotype
IgG2a
Target
NRBP1
Immunogen
Antigen Species
Species Reactivity
Applications
Application Note
Protein expressed in 293T cell transfected with human NRBP1 expression vector
Human
Human, Monkey
FACS, IHC, IHC-P, WB
Recommended Starting Dilutions:
WB 1:2000 IHC 1:50
Optimal working dilutions should be determined experimentally by the end user.
Cellular Localization
Form Supplied
Purification
Storage Buffer
Storage Instruction
Notes
Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
Liquid
Purified from mouse ascites fluids by Protein A/G affinity chromatography
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C
(aliquotted). Avoid repeated freeze-thaw cycles.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human
consumption.
GTX84003 IHC-P Image
Immunohistochemical staining of paraffin-embedded breast tissue using anti-NRBP1 mouse monoclonal antibody. (GTX84003, Dilution 1:50)
GTX84003 IHC-P Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-NRBP1mouse monoclonal antibody. (GTX84003, Dilution 1:50)
GTX84003 WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NRBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell
lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NRBP1.
GTX84003 WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-anti-NRBP1monoclonal antibody.
GTX84003 WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-NRBP1 monoclonal antibody.
GTX84003 FACS Image
HEK293T cells transfected with either NRBP1 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-NRBP1 antibody (GTX84003),
and then analyzed by flow cytometry.