Maternity Information Leaflet Information about Pre Eclampsia What is pre-eclampsia? Pre-eclampsia is a common condition that only occurs during pregnancy, affecting the mother, baby or both. It can develop from around 20 weeks of pregnancy to as late as several days after delivery, the severity of which can vary. In the mother, the condition causes high blood pressure and protein leaks from the kidneys into the urine, other symptoms may develop and are mentioned below. For the baby, growth may be slower than normal. How common is it and how dangerous is it? Pre-eclampsia affects around one in 14 pregnancies and is the most common complication of pregnancy. Pre-eclampsia is usually mild but in one in every 100 pregnancies it is severe. Who gets pre-eclampsia? No one can predict who is at risk of developing pre-eclampsia. However, you are at an increased risk of developing the condition if you have a strong family history of pre-eclampsia, if you have had pre-eclampsia before or if you are pregnant for the first time, or are pregnant for the first time by a new partner. Preexisting medical conditions may also increase the risk of pre-eclampsia developing including high blood pressure prior to pregnancy, diabetes, systemic lupus erythematosis, and kidney disease or if you have a raised BMI (Body Mass Index). What causes pre-eclampsia? It is thought that the condition probably originates in the placenta; this is the attachment between the baby and mother. It is thought that the blood vessels in the placenta do not develop properly affecting the transfer of oxygen and nutrients to the baby. It is also believed that genetic factors are involved, as women whose mothers and sisters have suffered with pre-eclampsia are more likely to get it themselves. 2 How is pre-eclampsia detected? Pre-eclampsia can develop anytime after 20 weeks of pregnancy. Most commonly pre-eclampsia is present if: • Your blood pressure is high and • You have an abnormal amount of protein in your urine Serial blood pressure monitoring, detailed urine tests and blood tests will help with the diagnosis of pre-eclampsia. Is pre-eclampsia the same as high blood pressure of pregnancy? No. many women develop high blood pressure. Most do not have pre-eclampsia. With pre-eclampsia you have high blood pressure, plus protein in your urine, and sometimes other symptoms listed below. About 1 in 5 women with high blood pressure progress to pre-eclampsia. Therefore, if you develop high blood pressure you will have regular ante-natal checks which can detect pre-eclampsia, if it occurs, as early as possible. What are the symptoms? The severity of pre-eclampsia is usually (but not always) linked to the blood pressure level. You may not have any symptoms at first; if pre-eclampsia worsens one or more of the following symptoms may develop: • Headaches • Blurring of vision, or other visual problems. • Abdominal pain (generally in the upper part of the abdomen, under the ribs.) • Vomiting • Just not feeling right Swelling of your feet, face and hands (oedema) is also a symptom of preeclampsia although it is also common in normal pregnancy. Oedema may become worse with pre-eclampsia therefore, if you notice a sudden increase in the swelling in your feet, face and hands you should inform your midwife. 3 What is the treatment for pre-eclampsia? Delivering the baby The only complete cure for pre-eclampsia is to deliver the baby. At delivery the placenta is also delivered, therefore, the cause of the condition is removed. After the birth, the blood pressure and any other symptoms in the mother usually settle quickly. It is common practice to induce labour if pre-eclampsia occurs late in pregnancy. The risk to the baby is small if he or she is born a few weeks early. The best time to deliver the baby has to balance several factors including: • The severity of the condition in the mother, and the risk of complications occurring. • How the baby is affected. • The chance of a premature baby doing well. Generally, the later in pregnancy the baby is born, the better. However some babies grow very poorly if the placenta does not work well in severe pre-eclampsia. They may do much better if they are born, even if they are premature. If pre-eclampsia is severe, then delivery sooner rather than later is best. If the pre-eclampsia is not too severe, then postponing delivery until nearer full term may be best. Other treatments Until the baby is delivered, other treatments that may be considered include: • Medication to reduce blood pressure: Medication to reduce blood pressure may be an option for a while if pre-eclampsia is not too severe. If the blood pressure is reduced it may help to allow the pregnancy to progress further before delivering the baby. • Rest: Rest is often recommended although there is little evidence that this makes much difference. It is sometimes necessary to admit women with pre-eclampsia to hospital, particularly if it is severe. This is not just for rest, but also to monitor the mother and developing baby. 4 Can pre-eclampsia be prevented? There is some evidence to suggest that regular low dose aspirin and calcium supplements may help to prevent pre-eclampsia in some women. These are not standard or routine treatments as the evidence for their benefit is not strong or conclusive. However, one or other may be considered by a specialist if you have a particularly high risk of developing pre-eclampsia. Will pre-eclampsia develop in my next pregnancy? If you had pre-eclampsia in your first pregnancy, you have about a 1 in 10 chance of it recurring in future pregnancies. There is no way of predicting if it will happen again. If you do not have pre-eclampsia in your first pregnancy, it is unusual to develop it in future if you become pregnant again by the same partner. 5 Help and information If you are concerned or have any questions please contact your community midwife or Labour Ward (St Richard’s Hospital 01243 788122 ext 2962) Worthing Hospital 01903 285230) Further sources for information and help APEC (Action on Pre-Eclampsia) Helpline: 020 8427 4217 (Weekdays 10am – 3pm) Web: www.apec.org.uk References RCOG guideline (No. 10), Management of eclampsia, November 1996 APEC patient information leaflets Pre-eclampsia patient information leaflet. www.patient.co.uk 6 Further Information NHS Choices Website — www.nhs.uk National Institute for Clinical Excellence — www.nice.org.uk Contact details: St Richard’s Hospital, Spitalfield Lane, Chichester, West Sussex, PO19 6SE Labour ward: Antenatal Clinic: 01243 831433 01243 788122 ext. 2871 Worthing Hospital, Lyndhurst Road, Worthing West Sussex, BN11 2DH Labour Ward: Antenatal Clinic: 01903 285138 01903 205111 ext. 84371 We are committed to making our publications as accessible as possible. If you need this document in an alternative format, for example, large print, Braille or a language other than English, please contact the Communications Office by: email: [email protected] Or by calling 01903 205 111 ext 84038. www.westernsussexhospitals.nhs.uk Department: Issue date: Review date: Author: Maternity Dec 2011 Oct 2014 Obstetric Registrar 7
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