• Defined: Tightly coiled
DNA
• Forms during cell
division
– New chromosomes
created for new cells
• 2 Parts:
– 1) Chromatids:
Ch
tid two
t
identical parts of a
chromosome
h
– 2) Centromere:
Joins
i chromatids
h
id
together
• Defined: Picture of an
individuals chromosomes
– Identify sex & chromosome
defects
• Size of final pair identifies
sex
– Same size: XX = female
– Different size: XY = male
• Normal human will have
46 chromosomes
Down Syndrome: What’s Wrong?
• Writing notation:
– 1stt: totall
chromosome #
– 2nd: Sex
S
chromosomes
– 3rd: extra or
missing
• Down Syndrome:
47, XY, +21
Turner’s Syndrome: What’s Wrong?
• Write the notation
for Turner’s
T rner’s
Syndrome.
45, X, -23
or
4 XO,
45,
O -23
23
Patau’s Syndrome: What’s Wrong?
• Write the notation
for Patau’s
Pata ’s
Syndrome.
47, XY, +13
Klinefelter’s Syndrome: What’s Wrong?
• Write the notation
for Klinefelter’s
Syndrome.
47, XXY, +23
• Diploid Cells = Cells
with the full set of
chromosomes
– Paired chromosomes
• Half of our chromosomes
come from each parent
(23 from each parent)
• Somatic (non-sex) cells
are diploid
• Created by mitosis
• Ex: Skin, Muscle, Nerve,
Blood Cells
What is the human diploid chromosome
number?
Remember…Diploid
Remember
Diploid = total number of chromosomes
Answer = 46
What is the human somatic chromosome
number?
Remember…Somatic cells are non-sex cells…
…Somatic cells are diploid…
…Diploid cells have the full set of chromosomes
Answer = 46
How many chromosomes are in brain cells?
Remember…Brain cells are non-sex cells…
…Somatic cells are non-sex cells…
…Somatic cells are diploid…
…Diploid cells have the full set of chromosomes
Answer = 46
• Haploid Cells = Cells with ½ the
total number of chromosomes
• Gametes (sex cells) are the only
haploid cells
– Ex: Sperm, Egg, Pollen
• Chromosome number is reduced
by meiosis
• How do humans gget 46
chromosomes?
Haploid sperm cell (23) + Haploid egg cell (23) = Diploid zygote (46)
What is the human haploid chromosome
number?
Remember…Haploid
Remember
Haploid = half number of chromosomes
Answer = 23 chromosomes
What is the human gamete chromosome
number?
Remember…Gamete cells are sex cells…
…Sex cells are haploid…
…Haploid cells have ½ the set of chromosomes
Answer = 23
How many chromosomes are in female egg
cells?
Remember…Egg cells are sex cells…
…Sex cells are gametes…
…Gamete cells are haploid…
…Haploid cells have ½ the set of chromosomes
Answer = 23
• What is the diploid chromosome number?
42
• What is the haploid chromosome number?
21
• How many chromosomes would be in somatic cells?
42
• How many chromosomes would be in brain cells?
42
• How many chromosomes would be in gamete cells?
21
• How many chromosomes would be in egg cells?
21
• How many chromosomes would be in muscle cells?
42
• How many chromosomes would be in sperm cells?
21
• Is this a male or female rat?
male
Quick Review
• Chromsomes are tightly coiled
strands
t d off DNA
• Diploid (somatic) cells contain the
entire set of chromosomes
• Haploid (gametes) cells contain only
½ the total number of chromosomes