Badges for Donar Recognition NATIONAL GUIDEBOOK ON BLOOD DONOR MOTIVATION MINISTRY OF HEALTH AND FAMILY WELFARE NATIONAL AIDS CONTROL ORGANISATION GOVERNMENT OF INDIA NEW DELHI-110 001 First Edition - 1990 Second Edition - 2003 Published by: National AIDS Control Organisation Government of India 36 Janpath, Chandralok Building, 9th Floor New Delhi - 110 001 Compiled, Prepared and Edited by; Association of Voluntary Blood Donors, West Bengal, 20A, Fordyce Lane, Koikata-700 014, India Printed at : Nabapress Private Limited 66 Grey Street Kolkata - 700 006 Contributors: Text and Research - Debabrata Ray with assistance from: Arunabha Chattopadhyay, Ardhendusekhar Dutta, Arunangshu Sarkar, Dipak Bose, Satyabrata Roy, Subrata Ray. Reviewers: AVBDWB: Bhaskar Bhattacharya, Jayanta Kumar Bhattacharjee, Ram Ram Chattopadhyay, Samir Kumar Gupta, Sujit Kumar Datta. NACO: P Salil, Viswa Nath Sardana, Zarin Soli Bharucha. Language Desk: Amal Kumar De, Paramita Chowdhury, Ramaprosad De, Sati Chatterjee - School of Language Management, National Council of Education, Bengal. Design, Setting and Layout: Thoughtshop Communication Private Limited, Kolkata. Photograph: Dhiman Ghosh, Rathindra Chandra Poddar, Subir Sen, Subrata Ray FIRST BLOOD BANK IN INDIA Established in March, 1942 at the All India Institute of Hygiene & Public Health, Calcutta Table of Contents Preamble Basic Concept of Blood Transfusion Service 7 9 History of Blood Transfusion History of Blood Donation Movement in India 11 32 Estimating Blood Need and Planning 36 Blood Bank Commercialisation in Blood Banking 40 43 Blood Donor Blood Donor Motivators 46 50 Basic Blood Science for Motivators 53 Indications of Blood Transfusion 65 Hereditary Blood Disorders 71 Transfusion Transmitted Infections Donor Selection 76 78 Theory of Donor Motivation 86 Principles of Donor Recruitment 92 Donor Recruitment Strategies 95 School Education Programme Women in Blood Donation Movement Blood Donation Camp 101 105 107 Donor Counselling and Care 116 Donor Recognition Donor Retention Panel Donors 120 126 130 Law and Transfusion Service 132 Ethics in Transfusion Service 137 Public Relations in Transfusion Service 141 Communication in Donor Recruitment IEC Materials for Donor Recruitment 145 156 Use of Mass Media 159 Donor Records 170 Quality Management in Donor Recruitment 173 Community Based Organisations 176 Leadership in Voluntary Organisations 181 Handling Errors and Complaints 186 Evaluation of Blood Donor Motivation Programme Research in Blood Donor Recruitment Modern Technology in Donor Motivation 190 192 195 Land and People 197 Common Questions and Answers References 199 207 Annexures National Blood Policy 212 National Blood Transfusion Council State Blood Transfusion Council 225 226 Drug Rules 227 Adverse Donor Reactions 239 Licensed Blood Banks in the Country 247 Training Modules for Blood Donor Motivators 248 Slogans on Blood Donation 259 Important Dates for Blood Donation Drives 263 State AIDS Control Societies Glossary 267 271 Name Index 279 Preamble ndia happens to be the first country in the world to produce and publish Ian official National Guidebook on Blood Donor Motivation as far back as 1990 as a WHO supported programme of the Directorate General of Health Services, Ministry of Health and Family Welfare, Government of India. On the basis of the recommendation of the first ever National Seminar and Workshop, exclusively on Blood Donor Motivation held at Calcutta on January 23, 24 and 25, 1985 with the participation of blood bankers and donor motivators from all over the country, along with a few experts from abroad, Director Emergency Medical Relief, Government of India under the auspices of the Directorate organised a few meetings and workshops at Delhi, Suraj Kund, Jamshedpur and Calcutta to prepare the National Strategies for voluntary blood donor recruitment. As a result of these exercises and the collective wisdom of many people, the first National Guidebook on Blood Donor Motivation saw the light of the day in June 1990. The whole work was coordinated by the Association of Voluntary Blood Donors, West Bengal. Indian blood banks, since inception, mainly depended on commercial blood sellers barring the periods of war and battles. Voluntary blood donation movement was launched by well-meaning individuals only in a few cities and towns in a sporadic manner. In 1980, the first attempt to tackle the social problem in an organised manner by actively involving the community as a whole — was planned on a regional basis. On a public interest litigation, the Supreme Court after appointing two expert committees and after hearing the advocates of all the parties at full length, delivered a historic judgement on January 4, 1996. The Judgement, inter alia, directed the Union Government to ban the buying of blood from commercial blood sellers in any blood bank of the country with effect from January 1, 1998. World Health Organisation directed that replacement blood donor system be phased out and abolished by 2005. With the formation of the National and State Blood Transfusion Councils, the health planners and the voluntary organisations are eager to achieve the much cherished dream of blood transfusion services dependent totally on voluntary blood donors to ensure safe blood transfusion. In the days of blood communicable life-threatening infections, all over the globe, efforts are being made to ensure safe blood transfusion by recruiting and retaining real voluntary blood donors. [7] he voluntary blood donation movement in India is at different levels in different states. In some states, blood transfusion service is totally dependent on replacement blood donor system; in some states, the movement is at its zenith, while in a few states it is still at its embryonic state. Blood donor motivation is an art based on science and should be practised with conviction and dedication either from within the transfusion service or from outside. In both the cases, there would be requirement for a large number of trained motivators who would be needing a guideline containing strategies and techniques based on experiments and experiences in advanced regions. The newcomers in the field instead of starting from datum level can start from the ground prepared by others earlier. The first edition the National Guidebook being out of stock, National AIDS Control Organisation entrusted the Association of Voluntary Blood Donors, West Bengal to prepare the second revised edition of the Guidebook for the donor motivators of the country. The Association, after consulting experienced motivators and organisations of the country, decided to rewrite the book suitable for the twentyfirst century with four sections: (1) Text (2) Annexures (3) Pictorial and (4) References, so that those who don’t have enough time or scope to do the library work or undergo training in any advanced center can get everything in between two covers. Opinion and materials were collected through exhaustive correspondence, email, meetings, workshops, research and library work. These painstaking efforts continued for little over two years. The second edition of the book is the work of many people from all over the country. Materials from different sources have been used freely, acknowledging the sources. The Association and its volunteers would have a sense of fulfillment if the current edition of the book which is the product of their untiring efforts, help people working for the promotion of voluntary blood donation to lead the country to a unique plateau where there would be no buying and selling of blood. Gift of love would flow from the healthy to the ailing as a natural social process to maintain the river of life flowing with all its glory singing the songs of sharing and caring as a real manifestation of humanism. Kolkata December 10, 2003 Debabrata Ray [8] Basic Concept of Blood Transfusion Service In the course of seventy five years, blood banking has developed from a bench in a corner of clinical pathology into a speciality of Transfusion Medicine. Beautiful, well-designed buildings with glow-sign and sophisticated plant, equipment, instruments, furniture and fixture manned by trained doctors, technologists, nurses, supported by modern computer and information technology cannot ensure the desired service in time of need of any ailing or dying patient unless blood is readily available. Replacement of ancient glass-bottles by modern poly-bags, introduction of gamma ray-sterilised disposable transfusion sets, extended shelflife of blood, use of blood components and plasma products, technology of pheresis and modern laboratory technologies have changed the quality of blood banking and blood transfusion service. But one thing that has not changed since the dawn of first blood transfusion of modern era, is the need of human volunteers to donate blood. Modern medical science is very service. Without blood there can be human blood donors, there can be regular flow of real voluntary blood keep blood bank shelves full, delivery at the right time can never be ensured. much dependent on blood transfusion no blood transfusion service. Without no blood for transfusion. Without a donors who have no axe to grind, to of good quality blood in right quantity But, all over the world blood donors belong to a minority community. India is no exception. It should be accepted and appreciated that: • Nobody is born as a blood donor. • There are several myths, misconceptions and fear complex arounds blood donation. • People do not donate blood unless they are asked to do so. • People are generally not self-motivated to donate blood. • There are more than enough potential blood donors in the country in respect of blood need. • People have to be motivated to donate blood to keep the blood bank shelves full. Naturally, to motivate people to donate blood is a fundamental task for any transfusion service. Awareness has to be generated for regular voluntary blood donation in the community. Misconceptions, fear complex and prejudices have to be removed scientifically by rationally emphasising [9] that blood donation is harmless to the donor; a social necessity and a friendly gesture of caring and sharing for the human society crying for compassion and respect. Philosophy and science of blood donation together with blood need for transfusion have to be propagated in a sustained, systematic and scientific manner in a listener-friendly language in the community. For this task, a large number of trained, dedicated blood donor motivators and recruiters are needed for this vast country with so much diversities in language, culture and religion. The work of blood donor recruitment would need scientific planning, careful organisation, rational outlook, pragmatic and appropriate direction, control and coordination. To many, even among the doctors, blood transfusion service is just another discipline of medical science or at best an emergency medical service. But, in fact, ideally, this service should be a highly coordinated and organised social service, linking the healthy with the ailing through a host of intermediaries like donor motivators, doctors, technologists, nurses and clinicians integrated into the system. Starting point of the service is blood donor recruitment through education and motivation. Every year a large number of young adults are attaining the age of blood donation. Every year regular blood donors are moving out from donor base owing to old age, ailment or change of residence. Blood donor motivation is, therefore, an ongoing process to change the behavioural pattern of non-donors. The work has no scope for respite. [10] History of Blood Transfusion The story of blood begins long before the days of written history when people used to live in caves. The primitive people knew nothing about blood. But they saw their own blood when they had cuts on their body. Some of them saw people bleed to death. They realised that their lives depended on blood. Why blood is red and what blood does was a mystery and magic to them. These people were mostly hunters. When they killed animals, they saw blood and discovered the heart and figured it out as important. This is known from the detailed paintings of animals on the walls of caves. The animals1 hearts were shown in some of these paintings. Of course, these primitive people didn’t know what the heart was for or how it moved blood inside the body. The earliest written medical records that mention blood, comes from people called the Sumerians, who lived thousands of years ago in the fertile crescent, in the land between the Tigris and the Euphrates rivers in middle eastern Asia. Ancient Sumerian doctors thought that blood was the seat of life. They thought that the liver controlled blood. A little later, in the same area, Babylonian priest doctors wrote about two kinds of blood: Day blood and Night blood. When they described day blood, they were actually talking about the bright red blood carried by arteries to feed oxygen and nourishment to all parts of the body. Night blood was the darker blood in the veins that took wastes like carbon dioxide to be expelled from the body through the lungs or bladder. Over 5000 years ago, in ancient Egypt, the physicians were learning more about blood. In a document written at the time, the heart and the circulating system — the blood moving system — were described. This document also tells about the pulse for the first time: “If a doctor puts a finger on the neck, head, hands, arms, feet or body, the doctor will find the heart there; for the heart reaches out to every part of the body and speaks in the blood vessels of every part.” At about the same time, 4500 years ago, on another part of the world, a Chinese Emperor named Hwang-Ti (builder of the Chinese Wall) wrote a surprisingly accurate description of the circulatory system and of the blood’s role in carrying food to all parts of the body. The early investigators were doctors who combined medicine with magic and religious rituals. They had to fit what they learned about the body into the religious ideas of their time, failing which, no one would listen to them. [11] The investigations were carried forward by the Greek philosophers at the zenith of Greek civilisation 2500 years ago. In the third Century B.C. a Greek doctor called Erasistratus recognised heart as a pump forcing blood in the system. He also figured out that the pulse could tell about a person’s health. Greek doctors trained in Greek schools carried on research when the Romans came to power in the Mediterranean world over 2000 years ago. They carried this research without instrument or equipment. Experiments on living animals were not done. They had strange ideas about blood vessels. While examining enemy bodies after death, these researchers came to a strange conclusion. They noted that one half of blood vessels contained blood, while the other half was empty. These early researchers thought that the empty vessels carried air. Today we know that these researchers were seeing arteries empty of blood some time after death. Born in 130 A.D., Galen, the famous Greek doctor who was also a philosopher and scientist wrote more than 400 books amidst his busy practice. About one hundred books have survived. Some of them deal with anatomical studies including blood vessels. Galen believed in the two blood systems in the human body. One system, he believed was filled with bright red blood, while the other system was full with darker blood. This false idea was akin to the early Babylonian belief. He thought blood was formed in the liver, where it picked up food and took it to the right side of the heart. Some of this blood seeped into the left side of the heart and was mixed with air pumped into the heart by the lungs. The movement of blood. Galen decided, was caused by a pumping action of blood vessels. He believed that this pumping action sucked blood from the heart and sent it on its way to the brain and through the nervous system to all parts of the body. The blood itself just disappeared into the body and was replaced by new blood that was manufactured in the liver. The popularity of Galen helped these false ideas to sustain for 1400 years. It was dangerous to doubt anything that Galen had written. On the other hand, in the dark ages no ‘witches brew’ could have been effective without its complement of human blood. The Romans are said to have drunk the blood of slain gladiators in order to rejuvenate themselves. The queens of Egypt used to bathe in human blood to become beautiful by slaying the slaves. In the Mahabharata, it is found Bhima took an oath to kill Duhsasana to drink his blood, which he actually did later. There was a popular belief that human characteristics like vice and virtue flow with the blood. Attempts were made in medieval Europe to change the character of the prisoners by injecting blood from noble people. [12] Transfusion techniques and equipment, as pictured by German surgeon J. S. Elsholtz in 1667. Elsholtz believed that mutual transfusions between a husband and his wife could transfer personality traits, thereby easing marital discord. Even as doctor began to understand the benefits of infusing blood, the ancient practice of blood-letting persisted. In this illustration. The Blood-letting, by the French artist Abraham Bosse (1602-1676), a barber-surgeon treats his wealthy patient. 13 Three illustrations from a 1679 treatise “concerning the Origin and Decline of Blood Transfusion.” The author of the work maintained that animal-to man transfusions, depicted in the top panel, had been “shown to be wrong,” while those from man to man, shown in the bottom two panels, should be “left to the test of experience.” [14] ` Blood bath To become beautiful IntheMahabharata drinking of blood of Duhsasana Bhima Drinking of blood by Roman and Greek Speculation about injecting blood to bring about rejuvenation or t cure disease continued over the centuries. The dying Pope Innocent VIII in 1492 was injected with blood taken from three healthy boys; the donor died, so also did the Pope. 1000 years after Galen’s death, Pictro d’Abano, a gifted Portuguese teacher, was put to trial because he dared to question Galen’s ideas. The famous anatomist Vesalius had to resign from teaching at a university of Italy for contradicting Galen’s theories. As late as 1553, Miguel Serventus, a Spanish doctor, was actually burned alive because he said publicly that Galen was wrong. Because people believed Galen, medical science of blood circulation was kept at stand still until 1616. 1616\ Dr. William Harvey discovered circulation of blood in human body On April 17, 1616 Galen’s hold on medicine was finally broken by an English physician named William Harvey, who had his medeical education 15 Man receiving blood from a lamb. This fanciful illustration, from a 1692 German medical textbook, depicts the experiments of those who attempted to transfuse lamb’s blood for the treatment of insanity. in Italy. In a public speech to a group of doctors, Harvey discussed what he had learned through research about the circulation of blood. It was the first accurate description of the way blood moves through the body. He talked about only one circulation system, where blood is forced through arteries by the beating of the heart and comes back to the heart through the veins. Harvey also disproved Galen’s idea that new blood was made from food each day and disappeared in the body. Harvey measured that the amount of blood that went through an adult body every minute was about 3.78 litres. He noted that if Galen was right, the body had to make 1,440 gallons of blood every single day! This was impossible. Harvey reasoned that the same blood had to be circulated through the body over and over again. Harvey knew that he was right, yet he was slow to tell the world at large about his ideas. He was afraid that everyone would be up against him. It took great courage in 1616 for Harvey to talk about his findings and research. He had to pay the price. His patients left. He was jeered in the streets of London. He was considered a crank. Gradually some listened to him. Harvey regained his good name. In 1628, he published his findings in a book. His book was banned in many parts of Europe. Not everyone scoffed at Harvey. In secret, many taught Harvey’s idea. One such teacher was Bartolomeo Massari of Italy. His student was Marcello Malpighi who was born in the same year when Harvey’s book was published. Malpighi, after his medical education, became a teacher at Pisa. He started teaching Harvey’s findings. In no time most of his students left as they would not listen to Harvey’s ideas. Malpighi persisted and some scholars and thinkers began attending his lectures. One scholar who thought Malpighi correct was a man named Borcelli. From him Malpighi learned about a new tool, named microscope, used in Holland. He procured a microscope and proceeded to study the only missing link of Harvey’s observation — a crossing over of blood from arteries to veins. With the help of the microscope, Malpighi could see the tiny blood vessels in which the cross over from artery to vein took place. He named these tiny blood vessels as capillaries, from the Latin word capillus, meaning hair. He declared his findings in 1661 just four years after Harvey’s death. With the discovery of capillaries the focus shifted from the circulating system to the blood itself. Long before the days of Harvey, blood letting originated in the ancient civilisations of Egypt and Greece, persisted through the medieval renaissance and enlightenment periods, and lasted through the second Industrial Revolution of modern era. It flourished in Arabic and Indian medicine. In terms of longevity no other practice comes close. Germ theory, basis of [16] James Blundell successfully performed human to human transfusions. His equipment was rudimentary as this contemporary illustration shows. William Harvey (1578-1657) demonstrated the circulation of the blood. The lower illustration i ’ d i f Jean Baptiste Transfused blood from animals to humans A collection of blood-letting instruments. Blood-letting as therapy endured for millennia, although there was no evidence to show that it worked. A transfusion at La Pitie hospital in Paris, 1874. This illustration is at least partially imaginary. It is doubtful that the blood would have fountained so neatly into the cup, or that it would have reached the woman’s vein before clotting. [18] modern Western medicine, was formulated about 130 years ago. The modern practice of transfusion is about seventy five years old. The path was paved by Harvey nearly 385 years back. But blood letting was faithfully and enthusiastically practised for more than twentyfive hundred years. This practice resulted in loss of many lives including the legendary Robin Hood and President Washington. In 1833 French doctors imported 41.5 million leeches for blood letting therapy. Harvey worked in Oxford among a group of brilliant scientists who called themselves Experimental Philosophy Club. His colleagues were so impressed by his methods that they undertook their own circulation work, even if they had been trained in completely different fields. Sir Christopher Wren, the legendary architect and Robert Boyle, the founder of modern chemistry, dabbled in circulation using hollow quill and bladder to inject opium and antimony into dogs and then milk, honey and wine in the human circulation system. This paved the path of intravenous injections. 1665 Dog to Dog Blood Transfusion by Dr. Richard Lower In 1665 a talented young doctor Richard Lower attempted to transfuse blood from one dog to another. He tried vein-to-vein transfusion which railed. After a series of experiments, Lower was successful by connecting the artery of one dog with the vein of another dog. This simple advancement became useful to transfusionists in centuries to come till the preservation of blood in the bottle. On November 23, 1667, Dr Lower and Dr Edmund King transfused blood from a sheep to one Arthur Coga who received 20 shillings for his cooperation and gave an address in Latin to the Royal Society on his experiences. [19] On the other side of the English Channel at France, Dr Jean-Baptiste Denis started transfusing animal blood to human beings from 1667. He used the blood of calf and lamb. There were many deaths due to transfusion, resulting in court cases. French Parliament officially banned all transfusion involving human beings. In 1678, the Pope banned the practice throughout Europe. So, there was not much work for nearly 150 years. 1667 Lamb to Man Blood Transfusion On December 22,1818 in London Dr James Blundell, having shown that the blood to be transfused must come from the same species, performed the first transfusion of human blood in cases of haemorrhage after child birth by using an instrument designed by him. It was a direct transfusion. By these means he was able to save lives of a number of his patients. Dr Blundell made two pivotal recommendations after a series of experiments: • Only human blood can be transfused to human beings. • Transfusion,could not be used for curing madness or change of character. It should be only to replace blood. However, progress was still slow. Transfusion of blood was not always successful and at times caused death due to lack of sterile procedure, clotting of blood in the needles and tubes and absence of knowledge about blood groups. Polish doctor F Gesellius compiled statistics about transfusion in 1873; he found that the death rate due to transfusion was 56 percent. Eminent doctors in Germany and Austria denounced transfusion as a showpiece that brought attention to the clinic at the expense of the patient By the end of the nineteenth century, the brief resurgences in transfusion [20] was causing so much human suffering and death that the procedure threatened to slide into another long eclipse. In those days it was not known how much blood a donor could part with. There were cases when the donors collapsed and almost died. Dr Alexis Carrel, a French researcher, an immigrant to USA, introduced a technique of suturing the artery of a donor to the vein of the patient to make a continuous vessel to prevent blood from coming in contact with air and the clotting process to begin. This, of course, was done without the knowledge of compatibility of blood type. The surgeon’s fee for such transfusion was a handsome $500. There were many deaths too. Dr Carrel became a celebrated man for ‘one of the most remarkable surgical successes ever achieved in the USA’. In 1912 he got the Nobel Prize. Next year the French acknowledged his brilliance and made him a Knight of the Legion of Honour but his genius was not utilised in France during the Second World War. In 1875 Dr Leonard Landois, a German scientist, mixed human and animal blood and observed the result under a microscope to find that red cells swelled up and burst. He found that a second reaction was possible. The transfused red cell would stick together in the patient, forming plugs that blocked the capillaries and the complex network of blood vessels in the kidneys. The same reaction happened in some human blood when mixed with other human blood. 1901 ‘A’ ‘B’ ‘O’ Blood Group discovered by Dr Karl Landsteiner 1940 Rh factor discovered along with Dr Wiener A Group B Group O Group [21] These deadly reactions were explained 26 years later by an Austrian pathologist Dr Karl Landsteiner at the Institute of Pathological Anatomy in Vienna. In 1900 while mixing blood samples taken from different persons in a test tube he noticed that under certain conditions the blood cells would clump. He decided to explore with a series of experiments. In 1901, he carried on the experiments in a straightforward way. He withdrew blood samples from himself and his associates and allowed the blood to settle until the red cells separated from plasma. In a series of test tubes, he mixed plasma from each person with the red cell of every other. Sometimes red cells would clump or even burst, other times nothing unusual would happen. He recorded the results of 22 tested specimens. He found blood seemed to fall into three distinct groups. The plasma from one group which he called ‘A’, caused the red cells of another group which he called ‘B’ to clumpand burst. Similarly the plasma from ‘B’ group clumped the red cells of Group A. Neither caused the red cells of a third group to clump. He first called this ‘C’ and later he designated it as ‘O’ Landsteiner himself belonged to ‘O’ group. There was no one in the laboratories belonging to AB group. In 1902 two of his students Dr Struli and Dr Decastello discovered a fourth group in Germany which reacted to both kinds of plasma. They labelled it as ‘AB’ group. Dr. Landsteiner migrated to the USA in 1922. He got the Nobel Prize in Medicine for the discovery of ABO grouping system in 1930. In 1910, Moss discovered that the plasma i.e. the liquid part of blood, also contains some chemical substance which interacts with the chemical substance present in the envelope of the red cell. DΓ Reuben Ottenberg of the USA after studying Landsteiner’s work in 1907, introduced cross matching of blood. It took thirteen years before cross matching became a standard practice in 1920, and that too after campaigning, experimenting and a few accidents. In the earlier days blood groups were much used in forensic and legal work. In 1920 Dr Leone Lattes in Italy developed reagents to determine blood grouping after a bloodstain had dried. The heritability of blood group gained legal standing. From 1924 blood grouping evidence of paternity exclusion and also baby swapping incidents in hospitals was accepted by extending Mendelian theory of inheritance. In the early years of the twentieth century doctors were learning transfusion by trial and error method. Nobody asked the transfusion - not the patient or the donor, not even the doctors. The procedure of direct transfusion was complicated and costly. Donors were difficult to find even from the near relatives. The doctors had no choice but to buy blood from sellers on payment of $50. [22] In 1913 Dr Edward Lindman of New York, USA eliminated the need of artery-to-vein transfusion by introducing multiple syringe method. The needle was put into the arm of the donor and kept in place for quite some time. The doctors shuttled back and forth from donor to recipient withdrawing and reinjecting blood with a syringe. The surgeons used to work quickly to avoid clotting of blood. In 1914, Dr Lester J Unger of Mount Sinai Hospital designed a stopcock that eliminated the need of multiple syringe. Needles in the hand of the donor were connected with rubber tubing and a four way valve. By changing the position of the stopcock, blood could be drawn into a graduated cylinder and then direct it to the recipient. Clotting of blood was delayed by spraying the apparatus with ether which kept it chilled. But the donor had to come to the hospital and face the inconvenience. So the medical world was on the lookout for anticoagulants to prevent the inevitable blood clot which after 3/5 minutes halted the blood transfusion directly from the donor by blocking up the needles and tubes. After blood grouping and cross matching, this was the third hurdle of blood transfusion. In 1860 the English obstetrician Dr John Braxton Hicks was the first to experiment with an anticoagulant and lost three patients as a result. Some other doctors tried hirudin, a chemical found in leeches. That also proved toxic to humans. Others used oxalates, bicarbonates and phosphates, all of which delayed the blood clot but were toxic or poisonous. Simultaneously in Belgium, USA and Argentina, experiments were made to use sodium citrate to prevent blood clottinq. The discovery of a satisfactory anticoagulant made indirect blood transfusion relatively simple. Dr Albert Hustin in Belgium on April 24, 1914 demonstrated the use of sodium citrate to prevent coagulation of blood in a glass jar and on November 14, 1914 at Buenos Aires in Argentina Dr Agote carried out the first successful citrated indirect blood transfusion. In January 1915 this was also done independently by Dr Lewison in the USA. He also improved upon the technique and standardised the amount of citrate to preserve donors blood. He wrote in his notes “Technique requires no special apparatus any country physician could use it”. But doctors raised several ‘ifs and buts’ to prevent the use of this technique for quite some time. Sodium citrate gave surgeons the time they needed to bleed a donor into a flask and slowly infuse blood into the patient after mixing with measured quantity of sodium citrate. But transfusion remained a laborious affair. No one was storing blood. Doctors viewed citrate as a short term anticoagulant to keep the blood liquid, long enough to complete transfusion. When a patient needed blood, the doctor had to recruit a compatible donor, [23] Bring him to the hospital and use the blood right away. True, transfusion had become an ‘indirect’ procedure; blood no longer had to flow directly from donor to recipient. Storing of blood had to wait till 1932 when in Russia Dr Andre Bagdasarov demonstrated the system of storing blood for 21 days at 4°C by adding a measured quantity of dextrose to the sodium citrate as a nutrient of red cells. 1914 Dr. Hustin discovered Blood preservation in bottles Now a days Blood in a bag is preserved for 35 days 1932 Andre Bagdasorov introduced Blood preservation for 21 days at 4°C In the thirties of the twentieth century, Hitler used serologists like Dr Otto Reche, Dr Ludwing Hirszfeld to establish his racial theory by causing a wrong interpretation of blood groups from predominately ‘A’ group among the white Europeans and ‘B’ group among the coloured Asians but carefully avoiding the incidence of ‘O’ and ‘AB’ groups among both white and colouredpeople. In 1926 Dr Alexander Bogdanov established the world’s first centre for Transfusion Research “Central Institute of Haematology” in Moscow. A lot of work on cadaver blood was undertaken in Russia. Even attempts were made to establish a cadaver blood bank. Scientists in Canada, India and the United States quietly experimented with cadaver blood. On March 23. 1930 Dr Serge Yudin at Skilifosvsky Institute named after the Russian pioneer of emergency battlefield surgery, transfused cadaver blood with success. He used the blood of a just dead person. Dr Yudin never understood why the blood of sudden death victims remained unclotted whereas the blood of those who suffered lingering death did not. Haematologists subsequently learned that only in cases of sudden death the body releases enzymes that dissolve blood clots. The attempt to use [24] By the 1930s arm-to-arm transfusions were becoming common. Above, a depiction of Dutch doctors transfusing blood directly from a nurse into a patient. During the Spanish Civil War, Dr. Norman Bethune. a Canadian surgeon and revolutionary, took blood transfusion to the Republicans in Spain. He ran a mobile transfusion service, speeding along the front lines delivering blood to the wounded. He is shown here assisting refugees during the 1937 evacuation of Malaga. [25] During World War II the Allies mobilised blood and its constituent parts on an industrial scale. Here, an American medico administers plasma to a wounded soldier in Sicily. Dr Charles Drew pioneered the industrial processing of plasma during the early years of World War II. He was lionised by the governmet as an exemplary Black American, at a time when blood donations were segregated by race. [26] cadaver blood was abandoned for logistical and legal reasons. The first blood bank of the world was established by Dr Norman Bethune during the Spanish Civil War at Madrid on December 10, 1936. Immediately thereafter, another blood bank was established at Barcelona by Dr Federico Duran Jorda by storing only ‘O’ group blood on the concept of universal donor. Having collected, processed, stored and distributed nine thousand litres of blood at his Blood Transfusion Center, he had no choice but to abandon the enterprise at the end of the civil war. He moved to England and was received by Dr Janet Vaughan who also took part in a British physician’s group that supported the Republicans in the Spanish Civil War. In doing so she became familiar with Duran Jorda’s work and became convinced” that like Barcelona, London must have stocked blood if it ever went to war. Together they established War Blood Transfusion Service in Britain. Britain entered into the war with only fifty bottles of blood but developed the transfusion service readily which after the war was converted into National Blood Transfusion Service. In 1937 Dr. Bernard Funtus, a doctor at the Cook County Hospital in Chicago, after reading about the work in Russia and Spain established a blood bank at his hospital, where he bled the donors into a flask containing a small amount of sodium citrate with dextrose, tested it, sealed it and stored it in a refrigerator. Funtus called the facility ‘Blood Preservation Laboratory’ but given the system of deposits and withdrawals soon came up with a snappier name immediately became part of the popular vocabulary. He, called it a ‘Blood Bank’. The date was April 25, 1937. Never before were these words used, although, the world had seen functioning of blood bank in some other name in Spain before. In Russia, side by side with cadaver blood, efforts were made to store blood drained from placentas and also from walk-in donors. In 1937, sixty large blood centres and five hundred subsidiary ones started using ‘canned’ stored blood amounting to ten thousand quart. Russians, in view of this pioneering work in blood transfusion and storing, had dozens of research institutes and fifteen hundred transfusion centres under the Health Ministry just before the war. Many of those institutes and centres working efficiently and effectively under the leadership of Prof - Andre Bagdasarov, the Director of Blood Transfusion Institute in Moscow, were converted to war blood transfusion centres in four divisions. During the first twelve months of the war, literally hundreds of tons of blood have thus been applied to wounded men in all stages of evacuations and with truly a tremendous success, wrote Dr Bagdasarov. Russians also produced blood substitutes including ‘Petrov’s Solution , a suspension of salt in sterile water and ‘Seltsovski’s solution’, a liquid designed to stimulate blood [27] producing bone marrow and the ‘Federov and VasUiev solution’, a gelatinous liquid designed to maintain blood pressure. These prevented shock for a few hours but none had the long lasting benefits of plasma or albumen. Nothing would match the Russians’ bravery, resourcefulness and ability to provide blood and transfusion fluids at the siege of Leningrad. At the height of the blockade, more than thirty five hundred people were dying per day. By the end of the “nine hundred day siege” more than 6,30,000 people had died but amidst the appalling suffering and destruction the staff at the Leningrad Institute of Haematology and Blood Transfusion carried on, often without water, electricity or even food. Britain did not have enough blood at the beginning of the Second World War. From the other side of the Atlantic, Dr Charles Drew, who invented the process of plasma separation, and whose famous thesis of ‘Banked Blood’ was of the thickness of New York Telephone Directory, considered as authoritative work on the science of blood storage, organised large scale shipment of ‘Plasma for Britain’ , as the first international medical despatch of blood products. In 1940, Dr Karl Landsteiner discovered the Rh factor in blood along with Dr Alexander Weiner. Two disciples of Dr Landsteiner. Dr Philip Levine and Dr Stetson proceeded to show along with Dr Weiner that Rh negative woman could be immunised to prevent haemolytic disease of newborn by injecting her with suitable immunoglobulin immediately after the birth of her first Rh positive child. By the late 1960s this injection became commercially available and with it began the era of ‘Exchange Blood Transfusion’ of new born babies of Rh negative mother by ‘O’ Rh negative or mother’s group specific negative blood. During 1940-41, standards of glass bottles for preserving blood were formulated. In the Second World War, glass bottles were the only containers for storing blood, but had some disadvantage in respect of transport, air dropping and storage space. Prof Carl W Walter of Harvard Medical School invented in 1947 blood containers made of PVC (Polyvinyl chloride) plastic resin. PVC containers were suitable for air dropping. Subsequently. Dr Walter proceeded to convert PVC bottles to bag by adding some plasticisers with PVC. These bags were flexible, soft, pliable. In 1961 U.S. Govt gave permission for mass production and marketing of poly bags. These bags, after further modifications are now being used all over the world. In the late eighties and early nineties of the twentieth century, further technological advancement increased the shelf life of blood to 28 days with [28] CPD and 35 days with CPDA and CPDA1. Thirty five day’s shelf life of blood is now in practice in India. But the western countries and some centres of India are using SAGM, ADSOL, NETRICEL to increase the shelf life to 42 days. During the Vietnam war, U.S.A. used liquid nitrogen to preserve blood, plasma and bone marrow for longer periods. Since the days of Dr James Blundell, blood donors were paid. Even when transfusion became indirect the doctors were depending on unreliable donor supply, recruited from the patients family or their own personal network, including individuals on payment. There were often no compatible donors. There was a time lag, often fatal, between the need and the supply. That was the situation Percy Lane Oliver confronted in London in 1921. Oliver, a balding bespectacled, bookish looking man, was the Secretary of the Camberwell Division of the British Red Cross in Southern East London. When a call came urgently requesting for blood with no other resources from whom to draw, Oliver and three co-workers rushed to the hospital. One had a compatible blood type and the patient survived. The dramatic rescue gave Oliver the idea of a city-wide bureau of providing pre-screened and pretested voluntary blood donors. He went on to maintain a donors’ panel. In the first year, doctors called him thirteen times, in 1925, 428 times. Oliver ran the organisation from his home, where aided only by his wife and a secretary, he worked 7 days a week recruiting, doing paper work and phoning volunteers. In 1926, he had 2000 outgoing and 3500 incoming calls. The service was free. For one donor, an average eight telephone calls were needed. Expenses for campaign, recruiting and travel of these voluntary donors compelled Oliver to raise money. These blood donors were known as ‘donors on the hoof. It had obvious limitations. Inspired by Oliver’s example and compelled the by pressing need, donor panels were established in Germany, Belgium, Australia, Russia and even in Siam. In Japan, Dr H Ijima established the Nippon Blood Educational Society with two hundred donors. In France, Dr Arnault Tzanck established the Emergency Blood Transfusion Society. Donors received small allowance to compensate for the inconvenience, most of which were raised from the public. Dr Tzanck was actually the founder of the International Society of Blood Transfusion. Dr Jean Pierre Soulier, one of his disciples who headed the French Blood Transfusion Service for thirty years wrote about Dr Tzanck that he was an incomparable motivator, who always preached that ‘the man is truly poor who does not know how to give’. If Tzanck represent the height of humanity and Oliver the epitome of unselfishness, then the Americans with their practical and market driven [29] methods embodied cool professionalism in mobilisation of donors. They saw nothing wrong in trading blood for money. Naturally, blood donors ‘bureaus’ were established by recruiting people who were selling blood fifty six times in a single year. Some of them carried syphilis and other blood communicable diseases. Horrified at the situation, eminent doctors in the field like Dr Ottenberg, Dr Coca and Dr Landsteiner in trying to raise the standard of professional donation formed the Blood Transfusion Betterment Association. It was actually a professional donors panel with rigorous standard of discipline, hygiene and testing. Donors received $35 and the bureau got a commission of $6. During the Spanish Civil War, appeals over the radio brought hundreds of donors. Patriotism prompted people to donate blood in U.K. Dr P L Mollison was entrusted with the responsibilities of recruiting donors in 1943. Unschooled in the art of recruiting donors, the great man and his colleagues hired a theatrical impresario, who plastered several neighbourhoods with posters for recruiting donors. In Russia during the Second World War more than two thousand people queued up in Moscow each day to donate blood. Donors received food and money for their blood, although, many returned the cash payment. All donors were women; most of the men had been called to the front. The use of the woman’s name on the bottle of transfusion fluid sometimes led to correspondence and friendship between the donor and the recipient, an occurrence that increased enthusiasm among neighbouring donors. In Calcutta the Britishers, the Anglo Indian community organisations having British chiefs provided the blood to meet the war need. and After the war all the conferences and declarations from international organisations recommended voluntary blood donation to ensure safe blood transfusion. Associations and Federations of blood donors started coming up. Red Cross joined in blood transfusion. An International Federation of Blood Donor Organisations (FIODS) was formed at Luxembourg in 1955. Not content with whole blood transfusion, advanced transfusion centres are now using blood components and plasma fractions. The blood of the patient is also collected before surgery to meet the blood loss during surgery. This is known an autologous transfusion. Red blood cells were first described in 1658. Vincenzo Menghini found iron in the blood in 1746 and Dr William Charles Weslls in 1777 showed that iron was in a complex substance subsequently named Haemoglobin. [30] In 1884 Russian scientist Dr Elie Metchnikoff found the role of white cells to destroy germs, in 1877. Dr Earnest Newmann showed that red cells and white cells were produced in the bone marrow. Dr Paul Ehrlich in 1879 established the basis of the differential count of the cell. Dr Emilvon Behring (1857-1917) received the first Nobel Prize in Physiology or Medicine in 1901 for his work on serum therapy, which opened the way to blood transfusion. In 1940. Professor Edwin Cohn and Professor Blomback at Harvard Medical School developed the process of plasma fractionation. Dr John Elliot demonstrated the efficacy of albumen transfusion. In 1964 plasmapheresis .was introduced. 1965 saw apheresis in a limited way. Professor Macforlaned in Oxford recognising that absence of the protein (factor VIII) was the cause of haemophilia introduced transfusion of fresh blood and plasma that laid the foundation for modern haemophilia therapy. This, in turn, led to application of fractionation technique on a commercial scale. Use of fresh blood for haemophilia patients was followed by fresh frozen plasma in 1965. Cryoprecipitate, discovered by Dr Judith Grahan Pool and her colleagues in Stanford, California and introduction of freeze dried concentrates made home therapy and prophylaxis for haemophilic patient possible. In 1971 Hepatitis B surface antigen (HBsAg) testing of donated blood was introduced. With the arrival of AIDS in the eighties, the panicky world of transfusion medicine could get the screening tests to detect HIV only in 1985. These tests were improved upon during the next fifteen years including some kinds of confirmatory and rapid spot tests. None of the tests can totally eliminate the window period but some costly sensitive tests available can reduce the window period. Thus altruistic genuine voluntary blood donors declaring truthfully their history of past ailments and health habits are the base of transfusion service to ensure safe blood transfusion. World Health Organisation had rightly declared 2000 AD as the year of Safe Blood Transfusion with a slogan ‘Safe Blood Starts With Me’. World Health Organisation, International Federation of Red Cross and Red Crescent Societies, International federation of Blood Donor Organisations and International Society of Blood transfusion have jointly decided to observe June 14 (birthday of Dr Karl Landsteiner) as World Blood Donor Day from 2004 with a slogan “Safe Blood starts with the blood donor” and thrust would be on youth Programme. [31] History of Blood Donation Movement in India In 1925, the Imperial Serologist started a Transfusion Centre at the School of Tropical Medicine in Calcutta. This was a service to draw blood from a donor by syringes and transfuse to the recipient without any storage in between. In 1939 the Indian Red Cross Society formed a Blood Bank Committee to support the Transfusion Centre with equipment and donors. By then the Transfusion Centre was collecting blood in a flask and transfusing to the patients, occasionally keeping the flask for a couple of hours in a refrigerator. The war necessitated establishment of a blood bank with storage for a considerable period. On March 6. 1942 under a Government order of Major General W C. Paton, I. M. S., Surgeon General, Government of Bengal, Calcutta Blood Bank the first real blood bank of the country was established at the All India Institute of Hygiene and Public Health, 110 Central Avenue (now Chittaranjan Avenue) Calcutta to meet the war need. The management of this blood bank was entrusted to the Blood Bank Committee of the Red Cross. To meet the blood need of the war casualties, the Britishers, British managed industrial and commercial houses, government employees and the Anglo Indian community came forward to donate blood. The blood bank team collected 39050 units of blood between March 6, 1942 and May 15, 1943 from Calcutta, its suburbs, including the railway head quarters at Nagpur, tea gardens of Assam and Darjeeling. Only 5458 units of blood were collected in the blood bank premises. After the war, this blood bank was handed over to the State Govt. and transferred to Calcutta Medical College campus. Nobody thought of motivating and recruiting voluntary blood donors during peace time. Professional blood sellers were accepted as the main source of blood to meet the need of the day. Blood banks were established in metropolitan cities of the country in the forties. In the fifties the district blood banks were established. All these blood banks depended on professional sellers. Nonavailability of blood in these government blood banks encouraged a number of doctors to establish commercial blood banks throughout the country. In 1954, the son of Mrs. Leela Moolgaoker, housewife of the Tata family met with a road accident in Bombay while travelling on a motorcycle. He was taken to St. Georges Hospital near VT Railway station. Blood was needed to save his life. Hospital employees and the employees of Tata House came forward to donate blood. The life was saved. But this incident [32] triggered off the need of oranising blood donation drives in the mind of Mrs Leela Moolgaoker. Mrs Moolgoker carried on her mission till her last day in 1992. In 1980 under the leadership of Dr H M Bhatia and Dr Z S Bharucha, Federation of Bombay Blood Banks was founded. In 1962, Dr V G Mavalankar an eminent surgeon of Ahmedabad, finding difficulty in getting right type of blood at the right time took up the cause of promotion of voluntary blood donation under the umbrella of Red Cross along with Dr Vani and carried on his self-assigned task till his death in 1984. Led by Dr Triguna Sen, then Rector of Jadavpur University, students and teachers organised first blood collection drive during peace time in West Bengal on August 4, 1962. In a month long daily blood collection drive, 301 students and teachers donated blood. Some of the donors of this camp initiated the move to set up the Association of Voluntary Blood Donors, West Bengal in 1980 with eminent doctor and social, worker Dr Labanya Kumar Ganguli as the president and established professional engineer Arunabha Chattopadhyay as the secretary to build up voluntary blood donation movement by involving the community and by using various innovative techniques. Voluntary organisations in the districts and subdivisions of the state were established and voluntary blood donation in the state became a statewide people’s movement At the moment, there are forty voluntary organisations working exclusively on blood donor motivation, recruitment and retention for the fifty eight government blood banks of the state. In 1962 Dr ML Gupta Director Indian Red Cross Society Blood Bank, Delhi initiated voluntary blood donation movement in Delhi by bringing in other voluntary organisations. In 1964 at Chandigarh, led by a housewife Mrs K Swaroop Krishen and supported by the then in-charge of the blood bank at P G I Chandigarh Dr JG Jolly, the Chandigarh Blood Bank Society was established to recruit voluntary blood donors. From Chandigarh at their initiative Indian Society of Blood Transfusion and Immunohaematology (ISBTI) was established on October 22, 1971. This organisation introduced All India Voluntary “blood Donation Day on October 1 in 1975. Since then, the day is being observed throughout the country. National AIDS Control Organisation (NACO) came forward to support the observance of this day from 1996. ISBTI has chapters in some states of the country. In 1967, patronised by the Tata House, Jamshedpur Blood Bank was established to recruit voluntary blood donors and collect, store and distribute [33] blood. In 1985, Voluntary Blood Donors Association, Jamshedpur, Bihar was established to work from outside the blood bank to motivate and recruit blood donors. In 1970, the students of Madurai Medical College, with the inspiration from their teachers Dr S A Kabir, Dr T Dorairajan and Dr T Chelliah set up Madurai Blood Donors Club to organise voluntary blood collection drive for the hospitals of the city. In 1974, Dr T Subramanian took over the charge and the club could do away with the professional blood sellers from the medical college hospital in 1983. In 1975, Mrs Shanti Ranganathan, a housewife of the TTK family, established the Madras Voluntary Blood Bank to spread the message of voluntary blood donation in the state. Subsequently, led by R Rajkumar, a bank employee, the Association of Voluntary Blood Donors Tamil Nadu was established in 1991 to function from the same premises to work for the same cause for the whole state. In 1985, the First National Seminar and Workshop exclusively on blood donor motivation took place at Calcutta. This three-day meet enabled field workers and the organisers working in the country to meet and share their experiences and inter state contacts and communications were established. The meeting after a whole night session, formulated a draft National Policy on Blood Transfusion, which was printed and circulated The proceedings of the said meet served as the hand book on blood donor motivation for quite sometime. This prompted the Government of India to constitute a working group and organise workshops and the National Guidebook On Blood Donor Motivation came out in June 1990. On the basis of the recommendations of the first-ever national meet on blood donor motivation, a link quarterly bulletin “Gift of Blood” came to be published regularly from Calcutta from October 1985. The bulletin has now completed its eighteen years. National meets on donor motivation were subsequently organized by different organisations in Mumbai, Chennai, Chandigarh, Indore, Pune. Jaipur, Tamluk, Bhavnagar at regular intervals. Even two International meetings on donor motivation and recruitment were hosted at Calcutta in1990 and 1995. Other voluntary organisations to recruit blood donors were established in Tripura. Assam, Madhya Pradesh, Orissa and Punjab between eighties and till the publication of this guidebook. [34] On a public interest litigation, the Supreme Court directed the Union Government on January 4, 1996 to abolish buying blood from sellers with effect from January 1, 1998 and asked the Government to constitute National and State Blood Transfusion Councils to promote voluntary blood donation. National AIDS Control Organisation established, in 1992, under its Blood Safety Programme has been supporting voluntary blood donation of the country. National and State Blood Councils were set up in July 1996 under the direction of the Supreme Court. The portions of the Drug Rules under the Drugs and Cosmetics Act related to blood banking were thoroughly revised and came into force from April 5, 1999 and subsequently modified thrice. National Blood Policy, after processing through all levels, was released on April 2002. The Action Plan for Blood Safety was released by NACO in May 2003. NACO had his first phase of programme between 1992-99 and entered in its second phase of the programme on November 9, 1999. The second phase would continue upto 2004. Thirty percent of the project cost is focussed on Blood Safety. The project finances HIV and other test kits, technical assistance on blood safety, and up gradation of equipment in government blood banking facilities. It also sponsors information, education and communication (IEC) campaign at both national and state level to generate awareness of potential danger of unsafe blood from unlicensed blood banks and professional sellers, and promotes the voluntary blood donation movement. Every year, exercise by way of workshops, seminars, conferences are being organised by National AIDS Control Organisation (NACO), World Health Organisation (WHO), Department of Science, Technology, Government of India (DST) and voluntary organisations to train up the blood donor motivators to embark upon a journey to achieve total voluntary blood programme for the country. “If there is one place on the face of the earth where all the dreams of living men have found a home from the very earliest days when men began the dream of existence, it is India. Romain [35] Rowland Estimating Blood Need and Planning O ne of the most important essential first move for blood donor recruitment is establishing clear goals by estimating pragmatically the blood need of the Country/State/Region/ Blood Bank. For a well established transfusion service, with a long history of success, knowledge of current patterns of blood usage and data of changes from year to year, it is a straightforward matter to project need into the future, to plan blood collection and recruit donors accordingly. The process is much more difficult at the beginning in regions or states where no data is available for any estimation at all. It is, therefore, quite natural that maiden attempts of donor recruitment may result in insufficient blood collection in reality. Surrounding every mountain peak, there are valleys and into these valleys one must go before climbing the peak. There are joys. There are disappointments. There will be success and there will be failure. Blood donor motivators should have a mental makeup to accept both the rough and the smooth. The journey of a thousand miles begins with the first step. And, a beginning has to be made. There may be three principal reasons for failure in the first venture: • Immature organisation • Lack of clear goals • Underestimation of blood need. When there is no blood, suppressed need of blood would not come to the surface. Blood need will increase with the availability of blood. Even donor awareness campaigns may inculcate the sense of need of blood in the minds of the clinicians and surgeons resulting in irrational use of blood. That should be taken care of when blood would become easily available from the blood banks. There may be a number of approaches for the estimation of blood need. Some are simple and some are complex in character. Some may give an approximate idea and some may give a fairly accurate target. To start with a goal, however approximate, a target is badly needed to set the ball rolling. [36] There are four approaches to estimate how much blood is needed: • In relation to hospital beds • In relation to total population • In relation to medical facility available in the region • In relation to past blood usage. Ideally, if 2% of population donates blood, it will be more than sufficient to meet the need of a country like India. For a population of 100 crores (1000 million), 2 crores (20 million) of intending blood donor would be more than sufficient for the country by taking into consideration all possible allowances. The present estimated blood need of India is 80 lakh (8 million) units. In the first method the need of blood can be calculated as 3 to 15 units per hospital bed per year. It may also be calculated as 7 to 20 units per acute hospital bed per year. In the primary health centres, the need may be 3 units per bed per year, while at a super speciality surgical hospital the need may be as high as 25 - 30 units /bed /year. The golden mean may be worked out. With the introduction of open heart surgeries, liver transplants and treatment for oncological disorders in the country, the need of blood in different regions have increased. The table below indicates the enormous variations of blood donor per 1000 population between different countries. Switzerland 113 Japan 70 Australia 58 New Zealand 56 Canada 55 UK 40 Greece 33 Singapore 24 Macao 23: Hongkong 27 Korea 22 Spain 21 Jordan 17 Malaysia 13 Zimbabwe 10 Mexico 10 9 Fiji 9 Philippines 7 New Guinea China 4 Brazil 2 Vietnam 2 Sudan 2 Ethiopia 0.4 [37] In India, this figure at the moment is 4 per thousand population with some regions/states at a higher than the national average and some below the national average. If this national average can be raised to 8 voluntary blood donor per 1000 population, there would not be any shortage of blood for the country and none would die for want of blood for transfusion. The ideal simple method of estimating blood need at the beginning would be to make a list of hospitals together with the details of bed strength of a region for which a particular blood bank or transfusion service is supposed to cater. This data is available with the health authority of the state. From this data, by counting the actual bed or acute bed, by using rule of thumb, blood need can be calculated by multiplying by the appropriate factor between 3 and 20 depending upon the standard of the health service . Another method may be to collect data about the requisitions received and served by the blood bank / transfusion service over a period of not less than three months. If such study had been conducted in the past, the results should also be studied. While computing such data, care should be taken pragmatically to: • Express all data on annual basis (if information availability covers only three months, it should be multiplied by four). • If data are not up-to-date, there should be interpolation and or extrapolation to allow for changes during the intervening period. • It should be ascertained that information collected is, in fact, complete. • Inconsistency between blood collection and blood usage should resolved before interpretation. It will be difficult to get data in many states due to poor documentation and improper record keeping system. Still a survey has to be undertaken. The survey may be based on the following questionnaires: • How many units of blood are collected by the hospital in day/ week/month/year? (any one) • How many requisitions are received in a day/week/ month/year? (any one) • How many units are asked for on an average per requisition? • Whether blood for the patients are obtained from other sources? • If so, what is the quantum? With these data, blood need can be estimated for the state/region/ blood bank for the year [38] The motivators have to collect another set of data i.e. actual storage capacity of blood bank(s) or transfusion service for which blood donor recruitment is being planned. The blood donor motivators should remember that the donor recruitment target should always be higher than the estimated blood need. The reasons are: • Recruited donor may not turn up on the day of blood collection. • Intending donor may be temporarily deferred on medical reasons at the time of actual blood collection. • Collected blood after testing may be discarded for containing blood communicable parasite/virus. Further, to meet each and every blood need, the services will have to stock blood more than the estimated requirement. As it is not known from which blood group patients would come, blood of all groups including rare groups is to be adequately stocked. There may be some marginal periodic so-called ‘wastage’ due to out dating of blood of some groups. A question can be raised: which is better, some one dying for want of right group of blood or some blood bags being discarded after the prescribed expiry period for want of requisition of that particular group? How do we feel if the unfortunate victim, whose blood need could not be met, is our near and dear one? A small portion of the collected blood, about 5%, may be outdated, another portion of about 1% may be discarded after testing, for various reasons. Some of the intending donors may be deferred on medical reasons; some intending donors may not turn up on the date and time of blood collection. Considering all these allowances and adding a blanket allowance of further 10%, the target of donor recruitment may be planned for the year and computed for month or week. Target of donor recruitment, annually, monthly or weekly should be at the finger tip of donor recruiters. A portion of blood would be collected in the blood bank but a goal has to be set. The goal should be pragmatic Estimation of blood need and planning the target of blood donor recruitment are the initial steps to identify the goal. The donor motivators/recruiters should assess, review and reset the goal from time to time by generating data from different sources. [39] Blood Bank O n April 25, 1937 Dr Bernard Fantus at Cook County Hospital in Chicago coined the word “Blood Bank” for the blood preservation laboratory equipped with the system of deposit and withdrawal. But blood banks had been established even before the nomenclature was coined. Blood transfusion service does not exist in isolation. It is an integral and indispensable part of the health care system. Today no hospital can function effectively without blood. Blood has to be provided to the patient in need in right time and right quantity. A stock has to be maintained. Only well planned and efficiently managed blood banks can meet the requirement of health care service. An Ideal blood bank has the following functions: • Blood donor motivation, recruitment and retention • Blood collection • Blood processing and storing • Blood distribution • Record keeping • Human resource development • Post blood transfusion follow up and research. The first task of any blood bank is blood donor motivation, recruitment. and retention. Without blood all other functions of blood bank become non-existent. Only the blood banks depending on voluntary donors motivated through education of self-exclusion can ensure safe blood transfusion by preventing transfusion transmissible infections. There should be steady supply of blood from voluntary blood donors throughout the year. There should not be any flush or lean season. Hence blood donor motivation in a scientific, systematic and sustained way is a demanding task. Some of the blood banks wrongly depend totally upon the ‘family donor’ or replacement donor system. There are, however, several reason why such blood banking system is unsatisfactory and dangerous. It may not be possible for the patients’ family to find a suitable family donor. Some may feel obliged to donate even if they know that they have some health condition which prohibits donation of blood. Moreover, since this blood meant for a particular patient, it is not easily made available to other patients, who may have a greater need. It is not possible, therefore, to utilise family donations effectively for running a blood bank with adequate stock of blood, ensuring its availability at right time of right group. [40] In addition, this system may ultimately lead to professional bloodselling system in disguise, has the potential to corrupt the personnel working in the blood bank. Since these are the people who have first access to the family, there is great temptation to accept pay offs for referring the family to the professional seller syndicate. Corruption of this kind thus introduces further dangers for the patient by subverting the professional integrity of the transfusion service staff. Systems of this kind are undesirable and should not be allowed to develop. The solution is to create a viable, ethical voluntary blood programme which succeeds in providing the required services. Paid donor system cannot succeed if something better is already in place. Blood banks, therefore, must have their own donor motivation, recruitment and retention programme, or may entrust one or more respectable voluntary organisations with the responsibility of undertaking. the job for them. There are four different models of blood banking service which have been tried successfully. These are: • Centralised • Regionalised • Coordinated hospital services • A coordinated mixed system. In India there are three types of blood banking service: • Government blood banks • Private non-profit making blood banks run by trust/society or snon-government organisation • Commercial blood banks. Government blood banks run on tax payers money from the public exchequer and therefore, they donot have to depend on total cost recovery from the patients. Non-profit making blood banks have to be funded from different sources including cost recovery from the patients. Commercial blood banks trade in human misery. Often their blood banking practices are unethical. Commercial blood banks have a high price for blood to meet the salary bills and the profit of the owners. Ideally, there should be a National Blood Transfusion Service (BTS) based on the existing model of National Health Service (NHS) in the United Kingdom (Britain). [41] Blood procurement Donor motivators procurement in time rules for providing blood. have to of need. face questions about procedures for blood Different blood banks may have different Some blood banks work round the clock and some work during daytime only. Even in 24-hour blood banks different services may have different working hours. Some have fixed hours for issuing blood for cold cases. Donor motivators must be conversant with all these working procedures so as to answer all such questions. One may have donated blood hundred times in camps. But the donor may not have visited any blood bank in quest of blood for his/her near and dear ones. This may be necessary once in a blue moon. So, the procedure of blood procurement is an important ingredient in awareness talk or campaign. This also helps in donor retention. For procuring blood, proper requisition is always required. Requisition from the attending clinician or surgeon and blood samples of the patient should be presented at the blood bank counter. While bringing blood from a blood bank the cross match slip must be obtained from the blood bank and made available to the attending doctors. The cross match slip certifies that donor’s blood and patient’s blood are compatible. In case the distance between blood bank and the place of transfusion is considerable, suitable container with ice-packing would be needed. Blood bank personnel have a great role to play in donor motivation, recruitment and retention. The best motivational exercise may go in vain if blood bank personnel do not reciprocate with donors with equal earnestness and respect. On the other hand a well meaning, courteous and sincere blood bank team may inspire many around a camp to become blood donor. Tender loving care and empathy from the blood bank personnel across the counter to handle patients’ relatives in agony with requisitions for blood for their near and dear ones help in donor motivation and retention. In fact, they are the ambassadors and public relations people of the transfusion service. They carry with them the immense possibilities of being the best motivators if they mean their job with sincerity, devotion and credibility born out of compassion for the ailing patients whose lives rest on a fraction of hope in quest of this vital life saving fluid which has no substitute as yet. [42] Commercialisation in Blood Banking Forall many years, monetary inducement of blood donation was over the world barring a couple of countries. In India all banks started functioning depending on poor paid blood sellers. relied on the blood Transmission of infection is a serious complication of blood.transfuion In spite of sophisticated laboratory techniques to screen blood from donors, safe blood transfusion cannot be ensured unless the quality of donors is assured at the source. Blood donors recruited in lieu of payment would be untruthful about their history of past ailments and sell blood by suppressing their health status particularly when they should exclude themselves. A global study has revealed that prevalence of infectious diseases in paid‘ donors’ is higher than in voluntary donors. Naturally, incidence of transfusion transmitted infections from commercial* blood banks is higher than those from non-profit making blood banks. To ensure blood safety, a move towards a totally voluntary blood donor service for all blood products has long been advocated at the international level. As already indicated, under the directive of the Supreme Court buying blood from blood sellers has been officially banned in India from January 1, 1998. But many transfusion centres or blood banks of the country, in view of banning of buying blood from professional blood seller have switched over to replacement donor system. They put the responsibility of bringing donor for the blood bank on the patient or their friends/relatives instead of going out to motivate and recruit voluntary blood donors. This has resulted in patronisation of blood seller system where money is not officially paid at the blood bank but unofficially outside the blood bank door by the patients’ relatives. The most serious danger of family donor system is that the difficulties described above may create entrepreneurial opportunities for the blood sellers to pose as family surrogates, on payment in an organised manner. Such systems have the ability to make the sellers dependent upon this activity for their livelihood. The resulting deep corruption may be difficult to eradicate, yet so dangerous to both the donor and the patient. The professional donor is tempted to give blood too frequently; stories are common of professional donors admitted to hospital in shock after several donations in one day. Moreover, it is not possible to rely upon health history [43] information provided by the professional donor because such ‘donors’ often come from economically and socially deprived sections of society. Therefore, there is a greater likelihood that the ‘donor’ will be anaemic and in poor general state of health. They will be less likely, out of financial need, to reveal any medical condition. In India, hospitals particularly specialised ones are in the metropolitan cities or in state capitals. Rural people coming to these hospitals cannot bring donors of required group with them. Naturally they fall prey to blood sellers. These blood sellers are poor people themselves who sell their blood for want of money caring little for their own health. They suffer from various ailments and are often drug addicts, alcoholics and carriers of blood transmissible infections. Their only concern is to earn money. It makes no difference to them whether the recipient suffers or dies because of the poor quality of blood. They often sell their blood at short intervals in different names to different blood banks. Often, their blood is poor in respect of haemoglobin content in view of their frequent blood letting. They hoodwink the haemoglobin test prior to donation in different ways such as by taking iron tablets orally. From the point of view of social values, buying and selling of human blood is a positive insult to humanity and can be compared with trading in human slavery. To the sick, counting days for a bag of blood, the community has a moral and social responsibility. Refusal to donate blood when one is fit to do so takes away one of one’s right to expect that somebody would donate blood in time of one’s need. There is another angle which must be emphasised. not a merchandise; it is a collection of living human tissues body the cells must be ‘fed’ to continue living). Trading in organisms cannot be legally permitted. And blood cannot market-mechanism. Awareness is also growing all over requirement of ‘safe blood’ is an “entitlement” under Rights” which cannot be denied to any individual. In Human blood is (Outside a donor’s such living human be priced by the the world that universal “Human some blood collection drives, donor-organisers lure donors by costly gifts having monetary value. The gifts do not ensure real voluntary blood donation. If enticements truly motivate people to donate blood, they have the same potential danger as ‘selling’. It brings in people who are not supposed to donate blood. Quality of blood collected from ‘donors’ with enticements having monetary value does not ensure safe blood. Thus, enticement serves no useful purpose. Instead, it adds the unnecessary. [44] costs and logistic complications. In a study at Kolkata it was revealed that costly gifts attracted more first time donors, who had a higher prevalence of viral blood transmissible infections but did not attract more repeat donors. Regular donors feel insulted by such gift. Real non-remunerated altruistic voluntary blood donors have the following advantages over the paid, replacement or directed donors: • Voluntary donors are not under any pressure to donate blood and therefore would be truthful about their health status. • They would meet the natural criteria of low risk donors. • They can be easily converted into regular voluntary donors. • Regular voluntary donors are more likely to be free from transfusion transmitted diseases. This is time tested. • They would self exclude themselves whenever not fit to donate in view of their education. • These voluntary blood donors would easily respond to the call for rare group donor or ‘on call’ emergency donors in view of their high level of motivation and commitment to voluntary blood donation. Therefore, elimination of commercialisation in blood banking can ensure safe blood transfusion. The starting point is recruitment of voluntary blood donors through education to meet the national need. Through awareness programmes common people should be motivated not to accept blood from commercial blood banks. There should be no coercion to get replacement donation. All government blood banks should provide blood to private hospitals and nursing homes. Conviction, dedication, enthusiasm, perseverance among the donor motivators and organisers within the transfusion service or from outside can eliminate the commercialisation in blood banking, of course, with adequate support from the government. [45] Blood Donor Blood India donor base is the foundation of any blood transfusion system. In any able-bodied individual between the age of 18 and 60 years can donate blood upto 168 times. After the historic directives of the Supreme Court officially, there is theoretically no paid blood seller in India from January 1, 1998. So, at the moment, blood donors are of two types: • Voluntary Blood Donor • Replacement Blood Donor. Voluntary Blood Donor: A voluntary blood donor donates blood out of his/her free will without expecting anything of monetary value from the blood bank or patients” relatives or any other source at the time of donation or in future. Acceptance of voluntary blood donor’s certificates, badges or cards is permissible according to the law of the land. Such recognition of donor is universal. Replacement Blood Donor: Replacement blood donor is a member of the family or a friend of the patient who donates blood in replacement of blood needed for the particular patient without involvement of any monetary or other benefits from any source. Normally, blood bank or transfusion centre provides the right group of blood for the patient and replacement donor belonging to any other blood group replaces the supply in quantity. But whenever blood is donated by a relative donor for a particular patient, it is called Directed Donation. Directed donation from relatives is not always safe. Husband’s blood given to wife can lead to antibody formation causing problems to the foetus in future. Blood from any blood relative such as father, mother, son, daughter, brother, sister can lead to serious medical complications. Even for transfusion transmitted infection, the close relation who had been socially pressurized to donate, are at times not able to disclose their risky sexual behaviour. Such donation should be avoided as far as possible to maintain ethical code of anonymity between the donor and the recipient and to avoid many future complications — social, legal, emotional. It has been proved universally and accepted non-profit blood is statistically less contaminated obtained from commercial or other sources. [46] all by over the world that diseases, than blood So, in the days of blood communicable infections, which are often fatal any ideal transfusion service should depend on real voluntary blood donors recruited through education. In view of the city based health care service in a predominantly agricultural country with a very low national income, rural people coming to city based hospitals are unable to organize replacement/relative donor to meet their blood need. More than half the population of the country is medically fit to donate blood. But 4 out of 1000 of the population in India are blood donors. So the reasons for not donating blood should be studied by blood donor motivators to convert the non-donor to donor. The reasons for not donating blood are: • Fear of the needle • Fear of pain • Fear of sight of blood • Fear of future weakness • Fear of possible ill effects • Objection from the elders • Apathy • Indifference • Social taboo • Medical excuses • Story of wastage of collected blood • Ignorance and illiteracy • Blood is sold at a high premium • Inconvenience due to location and timing of blood collection • Apprehension of post donation reaction • Has never been asked personally. Motivators should also know the reasons for present microscopic minority. Reasons for donating blood are: • Altruism • Service to the community • Sense of social duty • Gaining experience • Personal obligation • Personal appeal • Social pressure • Group pressure • For helping friends or relatives • For blood donor credit card • For recognition and awards [47] blood donation by the • • • • • Checking up health Reciprocity to pay back the social debt For- knowing blood group Seeing others donating blood Celebrities appealing to donate blood. Motivators should appreciate that in the materialistic the donor has some expectations. Expectations are: • Cordial reception • Painless bleeding • Clean and hygienic environment • Blood group and credit card • Proper utilisation of blood • Availability of blood in later time of donor’s need • Transparency of blood transfusion service. world of today It is well known that in the corner of every human heart there is a desire to do good to others without causing any harm to oneself and be remembered for the service, therefore, donors and non-donors should be handled keeping in mind the eternal human psychology. The donors have a right to know many things. Donor motivators should equip themselves to satisfy the quest of the donor for knowledge about blood and blood transfusion service, which includes basic blood science, blood group, its inheritance, principles of selection of donors, blood need of the state or region and present supply, procedure for procuring blood from blood banks in time of need. It should be borne in mind by the donor motivators that blood donors are not mere numbers in statistics but are human beings in flesh and blood and should be handled with tender loving care. Blood donors are the ambassadors of blood transfusion service. They can become donor-recruiters too, in course of time. The word of mouth from blood donors may bring credit or discredit to any transfusion service. Identifying Low-risk Donors The donor recruiter must appreciate that to ensure safe blood transfusion, identifying and recruiting low-risk donors is absolutely essential. Selection of low risk donors may be based on the following considerations: 1. Regular, voluntary non-remunerated donors or family replacement donors and commercial donors. are 2. People who give blood under pressure or for payment are less [48] safer than family likely to reveal blood transfusion. their unsuitability as donors. They are 3. Potential donors may be unsuitable to give blood because of: • their own poor health • they are not giving blood voluntarily • risk behaviour. 4. It is not possible to detect HIV antibodies period’. therefore during a the risk to ‘window 5. HIV seroprevalence is generally higher in blood sellers and even in the so called replacement or relative donors than amongst regular voluntary donors. 6. Every blood transfusion service and hospital blood bank should be aware of national criteria for identifying low risk donor groups and, therefore, potentially safe donors. They should concentrate on finding donors from amongst low risk groups by: • Avoiding unsuitable donors • Recruiting regular voluntary non-remunerated donors. 7. Potential donors who are in poor health should is only possible if potential bank staff should always confidential unit exclusion. be maintained. have engaged in high risk behaviour or who be encouraged to self-exclude or self-defer. This donors are made aware of risk behaviour .Blood provide opportunities for donors to ask for In such cases, strict confidentiality must always 8. Donors should be asked questions in donors who approach blood banks should be deferred. 9. Considering history-taking of units of blood is a great mistake. as a [49] barrier a private in area. collecting Result seeking large number Blood Donor Motivators Toare motivate, needed. recruit, and retain voluntary blood donors, dedicated people In whatever name we call them- donor motivator/donor organiser/donor recruiter/social worker/donor managertheir need is great for any transfusion service. They may work from within the transfusion service or from outside, to extend their voluntary service as labour of love individually or in an organised manner. Anybody having empathy, compassion and respect for the ailing patients in their quest for a new lease of life can become a donor recruiter or motivator. He/she should be appropriately motivated and enthusiastic enough regarding blood donation. The donor recruiters may be of three types: • Those who would like to organise blood donation camps in their place of work or their locality once or twice a year. • Those who would work as full-time staff within the transfusion service. • Those who would work closely with blood transfusion service as honorary trained volunteers on their own of on behalf of any social welfare organisation. The tasks of donor motivators are: • To build up a general awareness campaign message of voluntary blood donation deep community. • To recruit new donors and expand the donor base. • To retain donors and make them regular donors. • To organise outdoor blood donation camps. • To maintain a panel of rare group and on call donors. • To maintain liaison with donors, donor organization and blood banks • To assist in relieving emergency and shortage blood.. An effective donor motivator must with good public relations skill and stamina. be a blood The following are considered as qualities of Donor Motivators. • Compassion and Empathy • Understanding • Patience • Polite and pleasant personality [50] and spread down in donor, good the the organizer • • • • • • Imagination and Innovation Enthusiasm Strong motivation, conviction and dedication. Knowledge of blood, donation and transfusion service Competence in public relations Communication skill. The task of the donor motivator service in: • Donor recruitment • Donor retention • Donor recognition • Donor counselling • Organising camps • Record keeping • Planning IEC materials • Evaluation of programmes launched. would be to assist Knowledge of the land and the people, ability to psychology of non-donors and knowledge of blood and practice are essential for blood donor motivators. blood transfusion understand the blood banking Motivators can develop themselves by self study or library work or through observation in blood bank and blood donation camps. Those who have neither time nor facilities to develop themselves may avail themselves of the facilities of the structured workshop/training programme. It is not difficult to develop faculty members for such training programmes of any region through training and workshops by inducting people from different disciplines, having good communication skill. They should be blood donors and must have seen recruitment programme / blood donation camps. They must have direct knowledge of local blood bank (s) through visits and interaction. people from the field of bioscience, social science, management science, transfusion medicine, blood banking, haematology, pathology, medicine, surgery, education, journalism, public relations, theology, history, philosophy. literature may be groomed for this work through orientation programmes and teachers guidebooks prepared by experts in the field. After training, the motivators should be able to: • Have an understanding of the basics of blood science and science of blood donation. • Gather correct information and facts about blood donation and other related matter of the region. [51] • Learn the techniques of motivating people to donate blood. • Earn competence in conducting motivational meetings organising blood donation camps. • Develop skills in preparing materials for blood donor recruitment. • Apply all knowledge and experience so gained for the cause. They must acquire a good concept on the principles and strategies donor recruitment appropriate for the region. They must be competent answer all possible questions that may crop up in donor motivation sessions. and of to Curricula or the training modules have to be designed to meet all these needs. Designing curriculum requires expertise. Each curriculum must have clearly spelt out objectives and duration of the programme would depend on the background of the trainees, their assimilation power and depth of the content. All training modules should be evaluated and modified with time to meet the need of the era. Pretested training modules for blood donor motivators used by the Association of Voluntary Blood Donors. West Bengal appended in the annexure may be used for training of donor motivators. However, this is just a guide line. This may be modified to suit the need of the trainees. “A student acquires a quarter of his knowledge from his teacher, another quarter from his own intelligence, the third quarter from his co-students and the last quarter in course of time from experience”. -MAHABHARATA “Knowledge is not something to be packed away in some corner of our brain, but what enters into our being, colours our emotion, haunts our soul, and is as close to us as life itself”. - Dr Saruapalli Radhakrishnan [52] Basic Blood Science for Motivators is made up of minute elements Blood yellow fluid known as plasma. Each called cells suspended in a pale drop of blood contains primarily three types of cells - about 250 million red corpuscles, 400, 000 white corpuscles and 15 million platelets. Each of them plays a part in keeping the body healthy. Blood is red in colour. This red colour comes from red blood cells. Those cells contain a substance called haemoglobin, a combination of iron and other materials that give them the red colour. Haemoglobin makes it possible for red cells to pick up oxygen from the lungs and to carry the oxygen to all parts of the body. The trillions of cells that make up the body need oxygen to survive. As such, the red blood cell distributes its load of oxygen, it picks up carbon dioxide waste from the body cells and takes it to the lungs to be breathed out. Red blood cells have no power to move on their own. They must be pumped throughout the body in the blood stream. The red cells are manufactured in the bone marrow of the larger bones of the body. The red cells are continuously at work and they have an average life span of 120 days. New ones are made constantly at a rate of millions per second. [53] Blood carries Oxygen, Water and Food to all cells [53] Old blood cells are sent to an organ called spleen, where they are taken apart. The wastes are disposed of and iron is recycled to go into new red blood cells. Certain food such as red meat, cereals and green vegetables provide the body with iron. For donating blood one must have at least 12. 5 gm. of haemoglobin per 100 ml of blood. There are several types of white blood cells. Together these cells provide an active defence to protect the body when it is invaded by bacteria, viruses or other harmful substances. 60 to 70 percent of the white cells have a very simple mission. Their job is to attack and literally eat up bacteria and other harmful substances. They are the body’s first line of defence against infection and many illnesses. Another very important group of white blood cells protect the body against catching the same disease over and over again. These cells are especially effective against many diseases that are caused by bacteria and viruses. Many common diseases, such as chickenpox, are caused by viruses. The first time one of these diseases is caught, it triggers an immediate reaction from these special white blood cells. They begin to produce a substance called antibody meant to fight the virus. The antibodies are produced too late to prevent the first occurrence of the disease. However, the antibodies are stored away available to prevent the disease from occurring a second time. A different type of specific antibody is produced for each type of virus that causes disease. The white blood cells use the blood stream as a highway in order to rush to the site of an infection or illness. White cells are larger than red cells. They also have the ability to change shape in order to pass through the narrow twisting capillaries. White cells can get through some tight spots. Pus formed is actually the dead bodies of white cells. Platelets are tiny irregular shaped cells and. like red blood cells, are made in the bone marrow. Platelets are sticky. They can and do stick to each other and to the inner surfaces of blood vessels. When a blood vessel cut or punctured, platelets begin to gather at the site of the injury. The platelets stick to each other and to the edges of the injury, forming a plug that reduces the loss of blood. As the plug gets bigger, it becomes more solid and firm. It becomes a clot or scab, stopping the flow of blood and providing a foundation upon which the healing process can take place. The fluid part of blood called plasma carries all cells. consists of plasma while cells constitutes 45% of the blood. Out of the 55% [54] 55% of blood of plasma, 92% is water. The balance 8% of plasma consists of proteins, sugar, fats, vitamins and minerals that are needed by the body cells. In addition, plasma contains antibodies and hormones. Hormones are chemical messengers that regulate growth, physical responses to emotions and other body functions. Circulation of Blood Circulation is a movement, starting from a the same point. To maintain the movement, otherwise it becomes static, i. e.. circulation fails. point force and has coming back to to be applied, BRAIN PULMONARY ARTERY LUNGS . SUPERIOR VENA CAVA RIGHT AURICLE- PULMONARY VEIN AORTA LEFT AURICLE INFERIOR VENA CAVA CAPILLARIES RIGHT VENTRICLE LEFT VENTRICLE Circulation System in Human Body: In the human body the smallest living unit is a cell. To live, it must be fed and nourished. This process is achieved by blood. Irrespective of size, shape, function and location of the cell, blood must reach each individual cell. The bulk of the nutrients is derived from the food we take, which passes from the intestines to the blood in a fashion which is readily utilisable by the cell. For proper utilisation of the nutrient, another essential substance, oxygen is required. This is also carried by blood. But as we do not eat oxyen, the source of its supply is different. The source of supply of oxygen is the lungs. We breathe in air containing oxygen and this oxygen passes from the lungs to the blood, to be carried along with other nutrients to each cell of the body. [55] While oxygen is being utilised by a cell, it gives out a waste productcarbon dioxide. This is a harmful product and must be thrown out of our system. This process of throwing out is carried out by the lungs during breathing. The vehicle of carriage from cells to lungs is blood. Thus we see that blood, carrying nutrients, oxygen and carbon dioxide must be continuously moving from cells to the lungs and back to cells again. This is, therefore, circulation. Nature wants that once blood gets its oxygen from the lungs, it should not get mixed up with blood carrying carbon dioxide. So the human body is provided with two distinctly separate set of channels. The set of channels which carries oxygenated blood is called artery while another set which carries blood rich in carbon dioxide is called vein (There are of course two exceptions - pulmonary vein and pulmonary artery. The classical definition is vessels carrying blood away from the heart are arteries and vessels carrying blood towards the heart are veins. ). The arteries are linked to the veins by very tiny vessels called capillaries which are invisible to the naked eye. The movement of blood by a pump, which is the heart. through the arteries and veins is maintained The Heart As has been described, oxygenated blood and carbon-dioxide carrying blood must not come in contact with each other, the construction of the pump - the heart - conforms to this rule. I 24 hours heart pumps out 36,000 litres of Blood through a distance of 20,000 km. [56] The heart is a muscular organ divided into two compartments – the right and the left by a muscular partition. There is no connection (normally) between the two compartments. The right side is meant to receive and pump out venous blood and the left side is to receive and pump out oxygenated blood. Each compartment is again divided into an upper and lower chamber. Upper chamber of each compartment, called the atrium (plural atria), is to receive blood and then push it into lower chamber called ventricle. The opening in between the upper chamber and the lower chambers is guarded by valves, so that when pumping action takes place, the flow of blood remains unidirectional (one way traffic). The right upper chamber receives venous blood from each cell from the scalp to the toe. Once it is filled, it pumps its content into the right lower chamber, which then pumps blood into the lungs to get rid of carbon dioxide and to be oxygenated. The left upper chamber receives oxygenated. blood from the lungs, and this blood passes into the left lower chamber, which in turn pumps the contents (oxygenated blood) out to reach every cell of the body. Actually, therefore, the heart is a ‘2 pump’ organ. The heart in a healthy adult beats (i. e., pumps) at the rate of about 72 per minute. At each beat it pumps out about 70 ml of blood. Through its rhythmic contraction and dilation the heart maintains the circulation of blood. Distribution of oxygen by blood flow through the body [57] Blood Volume The amount of blood content in any human body can be easily derived from the empirical mathematical equations: V (Men) - 0. 3669H3+0. 03219W+0. 604l V(Women) = 0. 3561H3+ 03308W+0. 1833 Where, V is volume of blood in litre, H is height in metre and W is body weight in kilogram. Since most of us know our height and weight, the amount of blood stored in our body may easily be computed. Computation from the above formula reveals that normally a healthy man has roughly at least 76 ml of blood per kilogram of his body weight, whereas this amount is 66 ml per kilogram of body weight in case of a woman. Though blood content is generally proportional to body weight, yet fat in the body account for much less quantity of blood. Body fat accounts for only 11 to 22 ml of blood per kg whereas in other components of the body it is about 92 ml per kg. Blood Volume: No harm in Donating 8 ml. of Blood per kg. of Body Weight Men 76ml. per kg. of Body W i ht Out of the total quantity of blood (76 ml/kg or 66 ml/kg as the case may be] contained in the body, at best only 50 ml of blood per kg of body weight in the circulation system is more than sufficient for performing normal [58] routine work. Hence, the automatic deduction is that men have 26 ml/kg and women have 16 ml/kg, of blood in the circulation system as surplus or factor of safety. From this surplus, it has been scientifically established that if one slowly parts with 8 ml of blood per kg. of one’s own body weight, no harm is done to the body mechanism in any way. For donating blood in India one must have a body weight 45 kg. or more. Anybody having a body weight of 45 kg can donate 45x8=360 ml. In India not more than 350 ml of blood is collected from a donor. Those having higher body weight can donate more blood. But in a blood bank storing different quantities of blood in different blood bags would cause much problem at the time of distribution. So the quantity that can be collected from a 45 Kg. body weight person can also be collected from persons having higher body weight. For collecting 450 ml of blood it is desirable that the donor should have at least 55 Kg body weight. The liquid part of the donated blood is made up automatically within 2 days, and cells are completely replenished within 21 days. Still one is allowed to donate blood not more than once in 90 days i.e., three months after donation. For recuperation of the donated blood, which is only a fraction of the surplus amount, no additional nutritious food, rest or any medicine or tonic is needed. Normal diet is sufficient to make up the donated blood. Blood Group The blood of all human beings can be grouped or classified on the basis of presence or absence of particular chemical substances in the envelope of the red blood cells (known as antigen). Chemical substance present in the plasma (commonly know as antibody) interacts with the antigen and if incompatible causes the red cell to agglutinate. The plasma of a particular group will not contain any chemical substance which will cause injury to the red ceils of the same group. To elucidate, in the plasma of ‘A’ group blood, there will be no A’ cell destroying substance. On the contrary it will contain ‘B’ cell destroying substance known as anti ‘B’. Similarly, the plasma of ‘B’ group contains no anti ‘B’ but it contains anti ‘A’. The plasma of “0’ group contains both anti ‘A’ and anti ‘B’, while the plasma of ‘AB’ group contains none. The whole thing may be represented as follows: [59] Determination of Blood Groups The presence of ‘A’ and ‘B’ antigen in the red cell membrane forms the basis of determination of blood groups. Anti ‘A’ will be present in the plasma of ‘B’ group individuals and anti ‘B’ will be present in the plasma of ‘A’ group individuals. Blood from a ‘A’ group and from a ‘B’ group individual are allowed to clot. Afterwards the sera from the respective groups are collected and marked ‘B’ and ‘A’ respectively. A drop or two of anti ‘A’ and anti ‘B’ serum are placed on two different glass slides. 2 ml blood to be tested for groups is drawn in a syringe containing 0. 4 ml of 3. 8% sodium citrate solution and subsequently transferred to a container. A drop or two of the blood is placed on each of the slides containing anti ‘A’ and anti ‘B’ sera and slightly tilted for mixing. Agglutination can be observed under the microscope. The results interpreted on the basis of agglutination are as follows; If the red cells of the test blood are agglutinated by anti ‘A’ serum only, then the blood belongs to group A: if agglutinated by anti ‘B’ serum only it is group B; if agglutinated by both anti ‘A and anti ‘B’ it is AB group and if no agglutination takes place it is O group. Now a days tube method is preferred and mostly used. The main significance of blood group is for the purpose transfusion of compatible group. In other words. A group blood should be [60] of blood transfused to A group persons, B group blood to B group persons and so on. In transfusion reactions, the recipient suffers due to the donor’s incompatible red cells. In limited transfusion the plasma of the donor is suitably diluted and, therefore, has negligible effect on the cells of the recipient. So, in case of emergency. ‘O’ group blood can be transfused to persons of any other group as the red cells of ‘O’ group devoid of both ‘A’ and “B’ antigens will not be affected by the recipients plasma. On the other hand, the plasma of ‘O’ group, which contains both anti ‘A’ and anti ‘B’ will not affect the red cells of the recipient much. So, ‘0’ group is called universal donor. Similarly, ‘AB’ blood group which does not contain any antibody its plasma and as such can receive blood in emergency from all other groups and is. therefore, called universal recipient. The whole thing can be represented as follows: Who can Donate Blood to whom ? Donor Recipient A B A But in all normal should be transfused. cases, right group of blood after cross matching Cross matching and compatibility tests discovered by Dr Reuben Ottenberg in the USA. match serum of blood of the recipient with cells of blood of the donor and serum of blood of the donor with the cells of the recipient. Serum means plasma minus fibrinogen (protein present in plasma). [61] Rhesus factor or Rh factor Nearly 40 years after the discovery of the ABO blood groups, another type of blood group was discovered by Landsteiner and Wiener in 1940. They noted that reaction occurred in a large percentage of population when treated with antisera derived from rabbit or gunie pig immunised by red cells of a small monkey Rhesus Macacus. This is due to the presence of a different type of antigen in the envelope of the human red blood cells. Those individuals who possess this antigen are called Rh positive and those without it are grouped as Rh negative. But unlike ABO groups, the Rhesus group has no naturally occurring antibody. For transfusion purpose this factor should also be taken into consideration. Besides these two different systems of grouping mentioned, human red cells can be grouped by detecting the presence or absence of a host of different chemical substances in their envelope. To name a few, they are the Kell. Duffy, Kidd, MNSs. Lutheran, Lewis, Diego and Sutter systems. These are not taken into much practical consideration for transfusion purpose, but their importance lies mainly in anthropological and genetical studies. Why one should know one's own blood group Depending on the group, the blood of one individual may or may not be compatible with that of another. While it is generally known that the blood group typing of the donor and the recipient is a must before blood transfusion, there are everyday life situations in which we need to know our own blood group. Before marriage, it is advisable to check the blood group and Rh type of the couple. In case the Rh type of the bride is negative and the groom is positive, special care of the would-be-mother and the foetus is needed. Lack of prior knowledge of the blood type in such cases can lead to stillbirth or toxic conditions, resulting in loss of life. In pregnancy, the would-be-mother's blood group must be checked. During or after delivery, she may require blood transfusion, depending on the extent of blood loss. In the increasing pace of life, commuting day-to-day is becoming more and more risky. Accident rate has increased, one can meet with an accident whether one is driving a car or travelling in a public vehicle or even walking. In such an emergency, every minute counts. A prior knowledge of the blood group can save time and save a life. [62] Inheritance of Blood Group All our features and characteristics are controlled by genes which exist as the basic units of inheritance within our living body cells. These genes are, carried by chromosome - a thread like structure, present in the nucleus of living cells. Each gene has its own place in a particular chromosome and is responsible for a particular characteristic ranging from the colour of the eyes, hair to blood groups. Every cell - with the exception of reproductive cells (sperm and ova) - has 23 pairs of chromosomes, altogether 46, inheriting one set from each of the parents. Of these, 22 have been given numbers 1-22 and are called 'autosomes'. The-23rd pair consists of the sex chromosomes: X and Y The sexes are determined by females having two X chromosomes and males one X and one Y chromosome. The sperms and eggs (ova) have only half the number of chromosomes, one of each pair. During fertilisation, each parent, therefore, contributes half of each pair in the cells of the resulting embryo. Amongst our inherited characteristics there is a gene in chromosome No. 9 responsible for the specificity of our ABO blood group and another gene in chromosome No. 1 responsible for Rh factor. In other words, we inherit two blood group genes, one from each parent. For the ABO blood groups, chromosome from the mother carries one of A, B or O gene. Similarly, the other chromosome from the father carries one of A, B or 0 gene. A and B genes are dominant over the O gene. O is recessive gene. Thus a child inheriting A from father and 0 from mother would be AO i. e. A group. Similarly by inheriting A from father and A from mother the child will be AA i. e. A group. The AO or AA is called Genotype and A is called phenotype. The genes inherited [63] from each parent which are present on the chromosomes are called genotype and observable effect of the inherited genes i. e. the blood group itself is called phenotype. The table shows the possible combinations of genes and the blood groups they confer, Genotypes Phenotype (Blood Group) AB AB AA,AO A BB,BO B OO The Rh system, unlike the ABO system, has six genes called c, C. d, D, e, E. The genes travel in sets of three, with one set being received from each parent. But it is the presence or absence of the D gene that determines Rh positive or Rh negative. If the child inherits d from father and d from mother then and only then the child can be Rh negative, although the parents are positive with Dd, Dd combinations. But the child of Rh negative father (dd) and Rh negative mother (dd) must be Rh negative. 83% of the world population are Rh positive and in the Indian population 97% are Rh positive. I n h e r i t a Inheritance of the Rhesus factor [64] Indications of Blood Transfusion T ransfusion of whole blood from one individual to another is indicated for two main reasons: firstly, when the volume of blood within the circulation system of the patient is less than that required to sustain life and, secondly, when the red blood cells are deficient either in quantity or quality. If we have insufficient red cells, or if our red cells are abnormal, there will not be enough haemoglobin to maintain the body efficiently and we are then said to be anaemic. Blood loss through accident, surgery, or haemorrhage at childbirth, or from such a condition as the bleeding of a stomach ulcer, may reduce the amount of circulating fluid in our bodies below safe limits and we may die unless this loss is speedily replaced. Blood Supply from Govt. Blood Banks [100% ] Emergency Situation [17%] Post -operation Bleeding [9%] N=10000 Non Emergency Situation [83%] Planned Surgery [35%] Obstetric Emergency including exchange transfusion [6%] Obstretie & Gynaecological Cases[13%] Road and industrial Accident [1%] General Surgery including Tumour & Cancer [14%] Burn. Case [ 0. 7%] Malena[0. 3] Cardiac and Thoracic. Surgey [3%] Orthopaedic Surgery Haematological Case [48%] Thalassemia [20%] Severe Anaemia [15%] Leukaemia [7%] Haemophilia [6%] A study by AVBDWB at Kolkata Indications of blood transfusion can be summed up as: • Anaemia • Major Surgical Operation • Accidents resulting in considerable blood loss [65] • Cancer patients requiring therapy • Women in childbirth and newborn babies in certain cases • Patients of hereditary disorders like Haemophilia and Thalassaemia • Severe burn victims. Components In addition to being used as whole blood, blood can be separated into its components: red cells, white cells, platelets, plasma, cryoprecipitate which are used to treat certain conditions. One of the components, plasma, can be further subdivided by chemical procedures into its constituent parts, the socalled (plasma fractions] anti-hoemophilic factor concentrate, immuno globulins, plasma protein fraction and albumin etc. BLOOD COMPONENTS 1 unit = whole blood Red Blood Cells Platelets Plasma Cryoprecipitate Main blood products that can be prepared from one whole blood unit: Red Blood Cells, Plasma, Platelets and Cryoprecipitate. Transfusion of whole blood has long been a well-recognised life saver during and after major surgery and where there has been massive loss of blood in an accident or in childbirth. There are, however, various conditions which do not need whole blood replacement. For example, chronic anaemic condition requires transfusion of only the red cells of blood, Indeed, transfusion of unnecessary plasma may be harmful if the patient has a weak heart. Separation of red cells from plasma can be achieved either by allowing the container in which the blood is collected to stand for some hours during which the red cells will separate themselves from the plasma by gravity, or by spinning the container in a centrifuge, a machine which spins the container around a central axis. Adjustment of the number of revolutions per minute and the duration of spinning allow the different cells, e. g. red cells and blood platelets, to be separated from each other. Platelet transfusion These cells circulate in the body with the red and white cells and play an important role in the clotting process of the blood. Transfusion of platelets separated from several units of blood is now an important part of the treatment of platelet deficiency. [66] White cell transfusion It is now established that successful transfusion of white cells can assist patients to combat infections when, as it sometimes happens in certain blood diseases, the patients' body is unable to produce its own white cells, These transfusions involve the use of specialised techniques and cell separation equipment. It is not possible to collect sufficient white cells through conventional blood donation. plasma and albumin Plasma Protein Fraction (PPF) is a clear fluid containing approximately 5% albumin. This is an end-product of plasma fractionation, it is widely used for the treatment of surgical shock and burns or, in remote areas, to maintain the volume of fluid in the circulation until a patient can be removed to a hospital with full transfusion facilities, or until compatible blood can be provided. Thus, it is extremely valuable in small hospitals and to ships, which traditionally carried dried plasma (which has now been largely succeeded by PPF). A more concentrated solution of albumin, about 20 per cent, is also available. Fresh Frozen Plasma Fresh Frozen Plasma (FFP) is prepared from freshly collected blood by spinning it in a centrifuge. On separation, the plasma is immediately deep frozen and stored at minus 40°C. FFP contains all the proteins required for normal clotting of blood, and is commonly used in clotting factor deficiency usually caused by liver diseases. Cryoprecipitate This is prepared from Fresh Frozen Plasma by allowing it to thaw under conditions so adjusted that the Factor VIll settles out as a solid substance or precipitate. This can be separated by removal of the greater part of the thawed plasma after spinning in a centrifuge, and then deep frozen in packs. Cryoprecipitate also contains fibrinogen, another protein essential for normal clotting of blood. In some conditions, this disappears temporarily from blood and bleeding ensues. Transfusion of cryoprecipitate rapidly corrects the deficiency of fibrinogen and stops the bleeding. It can stored for one year at minus 40°C. factor VIII Concentrate This preparation has certain advantages over cryoprecipitate for the treatment of haemophiliacs. In particular, it enables them to be treated at It is also convenient for the control of bleeding when they undergo major surgery. This concentrate is prepared by fractionation of [67] Immunoglobulins These are substances carrying the antibodies which the body forms to protect itself against infectious diseases and foreign materials Immunoglobulins separated from the blood of healthy adults are valuable in preventing or attenuating certain infectious diseases such as measles and hepatitis. The blood of certain persons may contain particularly large amounts of one antibody for example, antibody against chicken pox or antibody against Rhesus factor D. The immunoglobulin prepared from such blood will contain high level of the antibody and is called, for example, anti-chicken pox immunoglobulin, or anti D immunoglobulin. Such specific immunoglobulins are of great value, particularly in case of Rhesus incompatibility between father and mother, which may lead to the birth of a child affected with haemolytic disease, the mother at risk can be sensitised with anti D immunoglobulins. Autologous Blood Transfusion In autologous blood transfusion, the patient serves as one's own blood donor. The underlying principle is that one's own blood will certainly be compatible and will not contain extraneous transmissible infections. The assumption is that 'one's own blood is the safest blood. ' This is true, but it should not be assumed that autologous blood can be used indiscriminately. Even autologous blood should be transfused only when absolutely needed. There are three basic forms of autologous blood use: • pre -deposit a) prior to planned (elective) surgery b) long-term (frozen) storage • pre-surgical haemodilution • Intraoperative blood salvage. Autologous Blood Collection Prior to Planned Surgery Persons who require surgery, but are otherwise in good health and able to donate blood safely, may reasonably donate blood for themselves prior to surgery. It is generally possible for a patient to donate 2 to 6 units o blood in this way, within a period of 2 to 4 weeks. A slight fall in haemoglobin level (not below llg-l00ml) is acceptable. Prescription of iron supplement, is usual which generally prevents the development of significant anaemic Some centres treat such patients with erythropoietin (EPO), a powerfu hormone drug which stimulates the production of red blood cells in the bone marrow. The use of EPO in autologous donor/patients is stil controversial because of the cost and the possibility of side-effects such a: thrombosis. [68] Autologous donation has become well established in preparation for certain orthopaedic procedures which are likely to require blood transfusion (e. g- spinal fusion) and has been widely used in plastic surgery. More controversial, but also widely practised, is the collection of autologous blood prior to cardiac surgery or caesarean section. Some industrial and advanced countries have active autologous transfusion programmes for paediatric patients; others accept patients of any age (including above 90 years), regardless of cardiac status. There are concerns about the potential risk of such aggressive programmes. Indications for Autologous Donation Generally accepted • Surgery will be required in the next 2 to 4 weeks • Patient can safely donate blood • Patient is likely to need blood during surgery • Patient is willing to undergo autologous donation Controversial • Pregnancy • Myocardial ischaemia, cardiac arrhythmias, cardiac insufficiency • Children • Donation of just one unit of blood • Blood is not likely to be needed during surgery Not acceptable • Risk of bacterial contamination of donated blood • Haemoglobin level less than llgm/100 ml. Apheresis Donation 'Apheresis' refers to a type of donation in which the desired component is selectively withdrawn from the donor while residual parts of the blood are transfused back to the donor during the blood collection process itself. Apheresis techniques are most commonly used to obtain plasma and platelets. The principal factor limiting the amount of blood that can be collected from a donor is the slow replacement of red cells after donation. By returning the red cells to the donor, it becomes possible to collect much larger amounts of plasma, platelets, leukocytes. Apheresis may be applied therapeutically (therapeutic apheresis) as well as to obtain Products for transfusion. [69] Plasmapheresis Plasmapheresis is useful in three distinct situations: • if the donor has some specific plasma factor which is required (e. g., rare or valuable antibody). • to obtain plasma products for regular patients from highly selected donors; • to obtain plasma for fractionation into specific derivatives (e. g., albumin, immunoglobulin, blood coagulation factors). Establishment of a volunteer donor plasmapheresis programme is a major decision. It is possible to develop large-scale programmes of this type, as has been demonstrated dramatically in Belgium. Many other countries have smaller but growing programme of this kind, for example Canada, France and England. The decision to initiate such a programme cannot be taken lightly because it requires a huge expansion in facilities, investment in cell separators, training of staff and complete reorganisation of the way the donors are recruited and organised. Cytapheresis Cytapheresis. or selective removal of specific cells like platelets, white cells etc. from the donor, while returning red cells and plasma with the help of machine known as cell separator. In case of platelet pheresis. sufficient platelets can be removed from a single donor in less than two hours to provide all the platelet needed for one patient. Naturally the donor has to stay in blood bank for longer hours. This also needs motivation. The donor recruiters have to be prepared to meet such requirement. Voluntary Blood donor Patient Whole Blood CENTRIFUGING Pached Red Cells plasma CENTRIFUGING Platelets Plasma FREEZING AND THAWlNG Cryoprecipltata Plasma SERUM LABORATORIES [70] Hereditary Blood Disorders T halassemia and Haemophilia are hereditary blood disorders requiring blood or blood product transfusion at regular intervals. There is no permanent cure as yet. Life is only prolonged by blood transfusion. Thalassaemia is a hereditary disorder, a kind of anaemia, characterised by a deficiency of normal haemoglobin. The disorder is also known as Cooley's anaemia. Mediterranean anaemia or Hereditary leptocytosis. Modern research has revealed that there are various types of thalassaemia. but the more prevalent is the homozygous beta thalassaemia, commonly known as thalassaemia major. Clinical symptoms of the disease are observed a few months after birth. These include anaemia, and later enlargement of spleen and liver. At about the age of four, stunted physical growth is seen accompanied by abnormally projecting upper jaws and prominent cheek bones. Bone marrow expansion takes place in the long bones, ribs and vertebrae and the bones become brittle leading to fracture easily. With blood transfusion therapy and desferal, the lives of affected persons may be prolonged. Inheritance of Thalassaemia A new life starts by the union of a male gamete (sperm) and a female gamete (egg or ovum). Each chromosome has several active regions called genes carrying the coded message for the synthesis of a particular substance. As the chromosomes are in pairs, the corresponding genes also appear in pairs. In normal persons, both the genes of a particular pair are normal, i. e. they carry the message for synthesising normal haemoglobin. But in some persons, one of the genes in the pair is normal and the other thalassaemic. This person is said to be a carrier or thalassaemia minor. The carrier person may be either male or female and has no apparent outward symptoms. When marriage takes place between two such carriers, then there is a 25% chance of their offsprings inheriting thalassaemia major. On the other hand, if one partner is normal and the other as carrier, then their offsprings will not be affected by thalassaemia major, but there is chance of 50% of their offsprings being carriers. Treatment and Prevention of Thalassaemia The lives of persons affected by this disorder may be prolonged by regular transfusion of normal blood, at an interval of three or four weeks. But blood transfusion alone is not sufficient treatment, for repeated transfusion tends to accumulate excess iron in the body, which affects the vital organs like liver, heart, etc. So, along with blood transfusion, the excess [71] iron has to be removed. This is done by slowly pumping a drug called Desferal under the skin from a small pump. But the best way of preventing the occurrence of the disease is to know before marriage whether both the partners are carriers or not. This can be done by performing a simple blood test, and if both the partners are found to be carriers, then such marriages should be discouraged or partners may be persuaded not to bear any child. Diagnosis is also possible during antenatal period which allows a choice for medical termination of pregnancy. Haemophilia Haemophilia, an inherited genetic disorder linked to the sex chromosome, is characterised by a marked increase in the coagulation time of human blood. The disease is transmitted by carrier females, who herself shows no symptoms, but the disease is manifested only in the male offspring. The blood is a fluid when, it flows through blood vessels, but clots when it comes out of the body. The blood of normal person clots in 5 to 10 minutes, while the blood of persons affected by haemophilia may [72] take 1-12 hours for clotting. The chemistry of blood coagulation involves an interaction of several factors and if any one factor is deficient or lacking, the coagulation time is prolonged markedly. In haemophilia, a normal plasma thromboplastin factor, which is essential for satisfactory thrombin (another essential factor for blood coagulation) formation, is missing. This plasma thromboplastin factor is a kind of globulin protein which is called Anti Haemophilic Globulin (AHG). It is also known as Factor-VIII. Inheritance of Haemophilia As explained earlier, sex chromosomes of females are XX and in males these are XY. The gene carrying the coded message of synthesizing the Anti- Haemophilic Globulin (Factor-VIII) is located in the 'X'- chromosome. In normal females both the 'X'-chromosomes have normal genes and in normal males one 'X'-chromosome present has normal gene. But in the carrier females, one of the'X'-chromosomes bears the normal gene while the other is haemophilic i.e., it lacks the normal gene. Now, when a female gamete (egg) with haemophilic gene on its 'X'-chromosome unites with a male gamete (sperm) having normal 'X'-chromosome, the resulting offspring will be a carrier daughter. These carriers have no problem with dotting of their blood, since they possess one normal 'X'-chromosome which is capable of producing sufficient quantity of Factor VIII required for blood clotting. But when a haemophilic egg unites with a sperm containing 'Y' chromosome, the resulting offspring will be a son. This son will be haemophilic, for it has no normal 'X' chromosome to produce Factor VIII. As the defective gene is located in the sex chromosome, it is called sexlinked genetic disease. Such patients would need cryoprecipitate or factor VIII throughout the life at regular intervals. Part of the family tree of Queen Victoria [73] Rhesus Babies (Haemolytic Disease of Newborn) If the father is Rh positive and the mother is Rh negative, the child can be Rh negative like mother or Rh positive like father. If the child is Rh negative like mother, there would not be any problem. If the child is positive like father then there can be problem, if not in first pregnancy but in subsequent pregnancies unless taken care of after the first delivery. About one child in 900 may be born as a 'Rhesus baby' Before delivery, blood may leak from the child in the womb into the circulation of the mother. Mother's defence mechanism is alerted with the entry of this 'foreign body'. She starts producing anti Rh positive antibody to destroy the invading Rh positive red cells. The antibodies remain in her blood for a few months after the delivery and may then disappear. But she is now permanently sensitised and if Rh positive cells enter into her circulation again at the time of a subsequent pregnancy she will respond after 72 hours by making anti Rh positive antibodies in a large scale, which passes into the baby in the womb and attack its red cells. Red cells of the baby are destroyed and release a pigment yellow in colour. The baby may die in the womb or is bom with Haemolytic Diseases of the Newborn (HDN). [74] To save the life of such babies exchange transfusion is needed. Exchange transfusion is the gradual removal of the baby's blood and its replacement by O Rh negative or mother's group specific negative blood. This blood for such transfusion should not be more than five days old. Now a days Anti Rh positive antibody (a protein called immunoglobulin present in the plasma of the people sensitised to Rh factor) is refined, and concentrated and injected to Rh negative mother within 60 hours of her giving birth to a Rh positive first issue. It has the effect of causing any Rh positive cells which have passed from the baby's to the mother's circulation to be neutralised in her blood. Rh negative mothers treated in this way do not become sensitised unless a large number of red cells have passed from the child to the mother. However, once a mother has become sensitised and has formed Rh antibodies, there is no method of removing them. This injection is administered only to Rh negative mothers who are not already sensitised and must be repeated at each pregnancy if the baby is Rh positive. It is of no value to already sensitised mothers since the leakage of blood from the child in the womb to the mother takes place at the last stage of the pregnancy. Often the child is taken out a few weeks before the full term by caesarian section to prevent complication. It is prudent to advise the family to organise one or two of O negative or mother's group specific negative donor well in advance before the scheduled date of delivery. If the situation warrants, these donors may be called upon to donate blood for exchange transfusion to the newborn. A timely action in such a case makes the difference between life and death. "Science may have found a cure for most evils, but it has found no remedy for the worst of them all — the apathy of human beings". — Helen Keller [75] Transfusion Transmitted Infections M alaria. Hepatitis (B&C), Syphilis, AIDS are considered as transmissible infections associated with blood transfusion. According to law all these tests are to be conducted after blood collection. It is not pragmatic to conduct these tests before blood collection as donors have to come twice, to suffer the needle pricks and may have to wait for quite some time. As a result, transfusion service may lose donors. So, donor selection can be on the basis of history of past ailments. After donation laboratory testing of blood should be undertaken in the blood bank. Presently, a sensitive screening test for malaria is not available. The most effective way of screening donors is to take the proper case history of malaria and of fever that could be due to malaria. Donor selection criteria should be designed to exclude potentially infectious individuals from donating blood. However, available slide test for malarial parasites is mandatory according to the rules now in force in the country. To reduce the occurrence of post transfusion hepatitis, it is essential to screen all blood donors for hepatitis B surface antigen, by the most sensitive and specific tests. Results may be made known to the donor with an advice to contact family physician for guidance. Hepatitis C can also be transmitted through blood transfusion. HCV antibody testing has become mandatory from June 2001 in India. Serum samples from all blood units must be selected for Venereal Disease Research Laboratory (VDRL) test before transfusion to detect syphilis. Any unit found positive should be discarded. But if blood is kept in cold room for three days, then there is no chance of contracting syphilis by transfusion of such blood as these germs become ineffective in cold. For transfusion safety, each and every unit of blood donated should be tested by combined HIV/1 and HIV/2 assay using ELJSA reader. This is just a screening test, and not a confirmatory test. Blood should be discarded if the test gives positive results but the donor should not be informed and should not be identified as HIV positive or AIDS patient. Strict confidentiality should be maintained. In smaller blood banks or in cases of emergency, rapid spot tests can be done to reduce the possibility of HIV/AIDS infection due to transfusion. But all these tests are not full proof. These are indirect tests to trace the antibody formed caused by the entry of foreign body from outside. Body mechanism takes time to produce antibody to fight against entry of germs from outside. There is a time lag between the entry of germs [76] and formation of antibody known as window period. The tests are ineffective during this window period. Motivators should, therefore, attach due importance not only to the truthful declaration of the donors but also to the pre-donation counselling for self exclusion to ensure safe blood transfusion. The confirmatory tests for HIV infection include Western Blot test and Immunofluorescence tests. These tests cannot be done in the blood banks due to high cost, time and expertise required. It has been observed that blood collected from genuine voluntary donors recruited through education based motivation are much safer and are very rarely to be discarded on the basis of the above mentioned screening tests. [77] Donor Selection A ll intending donors have to be screened before they are actually permitted to donate blood. This ensures safety of both the donors and the recipients. Donor screening has three primary objectives. Firstly, to ensure that the donor's blood has such qualitative standards as to be useful to the recipient. For instance, if a red cell suspension is to be transfused to a patient having severe anaemia, it is necessary to establish that the donor's blood has the requisite haemoglobin level to fulfil the purpose of transfusion. Secondly, screening of the donor is required to ensure that the recipient does not have any harmful reaction after the transfusion of the donor's blood, owing to offending agents being present in the donor. Thirdly, donorscreening also ensures that the donor does not come to any harm for the benevolent act. Donor safety is as much a concern of the blood banker as is the question of welfare of the recipient. With these objects in mind, donor-screening has to be undertaken in all blood donation camps as a necessary prerequisite before the actual blood donation. A trained social worker or a technician should be able to handle most of the work involved in this regard. However, it must be made clear that all blood donation camps must function under a medical officer, whose responsibility is to safeguard all interests of both the donor and the recipient, and that the medical officer of the camp must be the final authority for deferring or accepting a donor. Donor-screening is undertaken by (a) recording of personal particulars and history of past ailments and (b) physical examination of the donor by the medical officer. Selection Criteria General: The decision as to whether an individual is suitable for blood donation is based upon certain general criteria and upon the donor's health history, physical examination and tests done prior to donation. This decision is made before donation at the donation site. Some transfusion service personnel prefer to use a predetermination system on the day before the donation. However, there are two major disadvantages of this approach: a) it is inconvenient for the donor, involving the expenditure of time and travel on two different days; b) explaining a disqualification to the donor is [78] made more difficult and prone to breach of confidentiality. For these reasons screening on the previous day is generally not recommended, though there is a valid argument for using such pre-screening for new (first-time) donors. General information to be obtained from all donors should include the following: Name, address, telephone number, office address, employer, etc The necessity to identity and trace donors requires that all donors provide standard identifying information. This basic information is essential for follow-up, retention of the donor and for accurate maintenance of donation records, in situations where a donor who has been permanently disqualified, but for some reason attempts to donate again, accurate identifying information permits recognition of the unsuitability. Date of last donation Rules for frequency of donation vary from country to country; some stipulate the maximum number of donations per year while others spell out the minimum interval between donations. Some set different criteria for men and women. Whole blood donation must be restricted because the iron lost in a blood donation is not restored quickly from the diet. Frequency of whole blood donation should not be more than 4 times in a year. Date of birth (and age) This information serves to ensure that donors are not too young or too old to donate. Accuracy can be confirmed by matching stated age with date of birth. This information can also serve to confirm the donor's identity in situations where there may be more than one donor with the same name. The minimum age for donation is 18 years. It is legally the age of consent in India at which young people can reasonably be expected to be sufficiently matured to decide to be blood donors. Occupation It is better to know the occupation of the donor, to enable the doctor to instruct the donor on taking certain precautions applicable for those in hazardous professions, like flying, long distance driving and so on. Time of Last Meal All donors must be asked about the time when the donor took the last meal (major or minor), and about activities during the last two hours or so. The idea of such queries is to ensure that the donor has not been starving for more than 4 hours or that the donor has not been exposed to undue [79] exertions, sweating or dehydration. This situation particularly applies to suburban donors attending blood donation camps in the city, or for people starving voluntarily for religious or other reasons (Mohammedans during Ramzan month, or certain Hindus during Navaratri or other religious festivals). History-taking (i) Only for Lady donors The relevant queries should be made by a lady-worker or by a lady doctor or a lady volunteer from the organisation of the collection drive. Suitable questions are to be asked about the menstrual and obstetric history of the donor. (ii) For ail donors (including ladies) History taking concerns elimination of certain transmissible infections in the donor. Some donors may understand what malaria or jaundice is, but not all donors are expected to be knowledgable enough. For the latter category, specific question is to be asked for elimination of malaria. "Did you ever have fever, periodically (on alternate days or the like), with chill and shivering?" Whenever the reply is in the affirmative or is uncertain, suitable notes are to be made in the screening form, to enable the blood bank to undertake special tests. Donors with history of repeated attacks of malaria are to be deferred. Those that had a single attack, and were cured after due treatment, may be accepted after a lapse of three months from the last attack. Regarding jaundice, similarly, the question would be: "Did you ever have yellow discolouration of the eyes, accompanied by high coloured urine, and loss of appetite?" Donors with such history are not to be accepted within one year of illness. All such cases are to be referred to the medical officer. Another transmissible infection for which the donor must always be specifically screened is syphilis. It is preferable, however, that the donor is not asked directly about such illness, unless it is volunteered by the donor spontaneously. Such screening is done by later post-donation laboratory tests. The donor has also to be asked about any major illnesses like typhoid, malaria (during the last three months) or about any major surgery or bleeding illnesses (like piles) during the last six months. Such illness would lead to deferral of the donor. Donors receiving immunisation against viral diseases (like rabies, yellow fever etc.) or having suffered from any viral disease during the past one month or so are unacceptable. History of drug use of the donor is important for people who are under heavy antibiotic therapy, cortio-steriods (patients of bronchial asthma or skin diseases). [80] and antidiabetic drugs. These donors are to be deferred also. However, symptom free diabetic, not under drug therapy, are acceptable as donors. Donors giving history of allergic states (bronchial asthma, eczema, persons with history of skin rash after ingestion of certain food stuff) should be avoided. History of epilepsy, particularly in young adults, disqualifies the donor. There is yet another issue of tuberculosis of the donor. If the disease is active, the donor should be deferred outright. History of tuberculosis in past years has to be judged critically before deferring the donor. A donor who had tuberculosis, and has since been cured, is acceptable. Such acceptance must necessarily be at the discretion of the medical officer only, who may ask for radiological and laboratory evidence of the cure. History taking should be followed by a physical examination of the donor. Such examination must include weight check. The medical officer should undertake the general examination of heart, lungs, blood pressure etc. and decide on the acceptability or otherwise of the "donor on the basis of such examination, in collaboration with the history sheet, which is usually filled up by social workers. All these apart, the donor is screened by way of some laboratory tests. Estimation of the haemoglobin level is done before the actual donation. This is done by collecting a drop of the donor blood in a pasteur pipette and dropping it freely into a solution of copper sulphate (the specific gravity of which is 1053) from a height of one cm. If the drop, after the initial momentum of the fall, floats up eventually, it indicates that the donor has a haemoglobin level less than 12.5 gm/100 ml, and is unacceptable as a donor. If, on the other hand, the drop sinks into the solution, the donor is all right and acceptable. It has to be made clear that this method of estimating haemoglobin level is crude, and rather inaccurate. However, it has the time honoured sanction, because of its simplicity, quickness and low cost. To be effective, the blood bank worker must ensure that the copper sulphate solution is fresh, and is replenished after every 30 tests, or so. Unless this is done, the specific gravity of the solution will go down significantly, and blood drops from donors with haemoglobin levels below 12.5 gm/100 ml, will sink to the bottom of the solution, thus causing acceptance of unsuitable donors. The disposable piercing needle is required to be used once only to avoid transmission of infection in consecutive donors. The emergence of HIV/AIDS has revealed another type of donor population which must be excluded. Persons predisposed to sexually transmitted diseases are not safe blood donors and must be excluded. This is difficult because sexual practices are a sensitive and private matter and [81] sexually unsafe persons are not segregated or easily recognisable. It has become clear that male homosexuality is incompatible with safe blood donation, that prostitution and indiscriminate heterosexual activity facilitate the transmission of syphilis, hepatitis and HIV/AIDS. Intravenous drug abuse is a potent source of infection within groups who are sharing injection needles Furthermore, the recipients of unsafe blood products, most notably regular transfusion recipients like people with haemophilia and thalassaemia, also including certain recipients of sporadic transfusions, are more than usually liable to transmit dangerous infections to others. All of the above are unsuitable blood donors and must be excluded from blood donation. The same is true of their sexual partners. Individuals whose risk factors require exclusion from donation: • Homosexuals • Prostitutes • People having multiple Sex partners • Intravenous drug abusers (particularly multiple-use of needles) • People with haemophilia or thalassaemia • Sexual partners of any of the above. Techniques for identifying and excluding high risk persons: • Direct questioning, including specific questions about sexual practices or by circulating information sheet. • Physical examination, including a search for stigmata puncture marks of drug abuse by syringe, • Facilitation of self-exclusion by those at risk, by providing explicit written information to all donors in a confidential way to inform the Blood Transfusion Service that the donated blood should not be used for transfusion, and confidential procedure at the time of donation informing all individuals known to be specifically • at risk that they should not donate blood. • Maintaining confidential data concerning persons who have been permanently excluded from blood donation (donor deferral register). • Discouragement of persons tempted to give blood so as to obtain results of blood tests. Notwithstanding the generality of the standards mentioned above, each donor is to be assessed for acceptance or otherwise, in his or her own merit, and that, the final decision must lie with the medical officer of the blood bank, who would be held responsible. Translated into other form, it may be said that while it remains the duty of the citizen to volunteer to donate blood for the cause of the afflicted fellow - human, it is up to the [82] blood banker to screen the volunteer effectively in the interest of the welfare of the recipient and safety of the donor. Deferral General: The exclusion of anybody who is willing to be a blood donor is a delicate task for any Blood Transfusion Service (BTS). Nevertheless, the safety of the donation process and of the blood supply are at stake. Systems for the exclusion of unsuitable donors must be reliable and error free. At the same time, the community's resource of healthy blood donors must be protected and encouraged. What this means, in practical terms, is: • donors who must be permanently disqualified must be identifiable and must be effectively excluded: the donor should be informed of the reason and referred for further investigation, if necessary. • donors who are temporarily deferred must be clearly informed of the reason and actively encouraged to return after a suitable interval. • active donors should be informed about these procedures while being reassured that, in their own case, continued regular donation is quite safe and is encouraged. Temporary Deferral In all cases, the donor must be informed of the disqualification and the reason for it. A written explanation should also be provided to the donor. The explanation requires sensitivity, with the understanding that the donor may feel upset and dejected and therefore needs encouragement and support. It is particularly important that the donor understands clearly that the deferral is temporary and that further donation is encouraged after a suitable interval. No transfusion service can afford the permanent loss of donors whose deferral need only be temporary. The donor should be told when it will again be possible to donate. A Donor Deferral Register would be useful. If the donor's condition seems to warrant referral to a physician, this recommendation can appropriately be made at the time of the deferral. A written record of all referrals is essential. Regular Voluntary Donors Voluntary blood donors who give blood regularly are considered to be donors at the lowest risk of all, because their blood is tested frequently and they are less likely to attend the donation site if they know that they have engaged in any risk behaviour. Since they donate blood regularly, [83] they help to ensure that there is normally an adequate supply of blood, and they can also be relied upon to donate blood in emergencies. Blood transfusion services and hospital blood banks should therefore always encourage donors to become regular donors. Individuals who have donated blood at least three times and who continue to donate at least once a year (or whenever called on to do so) can be regarded as regular donors. Some centres use stricter criteria to define regular donors. They may, for example, require donors to give blood at least two or three times a year before they can be considered regular donors. Donor Self-Exclusion and Self-Deferral Encouraging donor for self-exclusion and self-deferral is a very important part of recruiting donors whose blood is likely to be safe. Selfexclusion means that potential donors make the decision not to give blood because they recognise that their blood may be unsafe for the recipient as a result of risk behaviour or because of the state of their own health, selfdeferral means that they wait until the condition that makes them unsuitable has been resolved. Every donor motivator has a responsibility to educate existing donors and the general public, who are potential donors, about the importance of avoiding risk behaviour. It is also essential that a motivator is trained to counsel donors about risk behaviour and to encourage them to self-exclude if they have engaged in any behaviour that may have exposed them to the risk of transfusion-transmissible infection. Confidential Unit Exclusion Some donors may be unwilling to self-exclude or self-defer, even if they know that their blood might be unsafe, because they do not want other people to know why they are reluctant to give blood. For example, if you are visiting a factory to collect blood, some people may donate because their friends or their manager expect them to do so. They may be worried that, if they refuse, others may suspect that they are HIV positive and will be hostile towards them. This is known as 'peer group pressure'. Because of this, it is important to give all donors the opportunity to tell motivators/social workers in confidence to remove and dispose of the blood they have donated. This is called confidential unit exclusion. Strict confidentiality must always be maintained when donors ask for unit exclusion. It is imperative for the donor motivators to make themselves conversant with the standards for donor screening prevalent in the country [84] at least, to satisfy the inquisitiveness of the listeners in the question-answer sessions. Drugs and Cosmetic Rules, as amended in 1999 prescribe the criteria for blood donor summarised hereunder and should be strictly followed. (i) Age . Between 18 and 60 years (ii) Weight: 45 kg. or more (iii) Pulse : 60 to 100 beats per minute and regular (iv) Blood Pressure : Systolic 100 to 180 mm of mercury; Diastolic 50 to 100 nam of mercury (v) Haemoglobin : Minimum 12.5 gm/100 ml of blood (vi) Oral temperature : Not exceeding 37.5°C. Before each donation queries shall be made to determine that the donor is in normal health and has not suffered from or is not suffering from any serious disease or illness like malignant disease, epilepsy, renal disease, allergic disease, abnormal bleeding tendency, unexplained weight loss of a significant degree, cardio-vascular disease. None should be accepted as a donor during the period of pregnancy and till six months after delivery and during lactation and also in case of excessive menstrual bleeding. Persons immunised or vaccinated can be accepted after two weeks if they are symptom-free. In case of bite by any rabid animal, the donor can be accepted only after one year. Those receiving anti-tetanus, anti-venom, anti-diptheria, anti-gas gangrene sera may be accepted four months after the last injection. If there is no history of having suffered from hepatitis within a year, the donor will be accepted. Donors having a history of malaria and treated with anti-malarial drugs may be accepted after three months. Donors are acceptable six months after recovery from any major operation and three months after the recovery from minor operation. One can be allowed to donate blood once in twelve weeks (3 months). The medical officer of blood bank shall explain to the donor any clinically significant abnormality detected at the time of donor screening. [85] Theory of Donor Motivation T he words motivation, innovation and communication have Latin origins. Motivation comes from the word motive, which in turn derives from the Latin verb movere', meaning 'to move'. So a motive, quite simply, is something that moves one to action. Characteristically the words 'motive' and 'motivation' suggest that something within one is at work impelling or driving the person. It may be a need, desire or emotion. Any single action can be driven forward by more than one motive. In other words, motives are often mixed. People are identical in-as-much as they share the same general physical and mental characteristics. At the same time, each individual is a unique product of genetics and environmental influences. We are all born with individual sets of characteristics and are then continuously influenced for the rest of our lives through contacts with other persons ranging from parents, relatives, friends, teachers, colleagues, political and religious leaders by education, training, books, films and jobs coupled with a variety of experiences. Life is a process of continual learning, modification and change. Depending on factors such as intelligence, background, schooling and sensitivity, some people are more disposed to learn or help others. No human being, however, can avoid the influence that comes from the external environment. The effects of these influences on behaviours are not always perceived at the conscious level. Individuals may change their behaviour without being aware that other person or experience has initiated the change. The external influence might shape values, attitudes, perceptions, motivations, judgements and decisions. Values and attitudes developed through' motivation are important determiners of behaviour. Motivation is the impetus that drives people to behave in various ways and seeks to fulfil a variety of needs. We all have needs. In the age of the great Epic the Mahabharata, Lord Krishna in the battlefield of Kuruskhetra (circa fifteenth century B.C.) delivered a lecture consisting of 745 verses in eighteen chapters to motivate the great warrior Arjuna to fight for a cause. This book, the Bhagabad Gita, is an algorithm of motivation for decision-making. Mastow, Herzberg and Vroom among the social scientists have earned universal fame for their studies on human motivation. The theories of [86] motivation studies as produced, vary in their emphasis and conclusions, but there is a general consensus: • Motivation is a force that drives people to satisfy needs. • Needs that people seek to satisfy are universal. • The motivational force has a direction towards specific goal. • The intensity of motivation depends on desire. • The motivational force may be short or long lasting. • With the satisfaction of need, motivation terminates and may be transferred to a new goal. • Motivation is the result of individual's perception of personal value system. • Two great movers of the human mind are the desire of good and fear of evil. In the field of blood donor motivation, the oldest theory on earth the "carrot and stick" principles of man management - never motivates real altruistic blood donors. Similarly, money cannot ensure good quality of blood for transfusion. No theory of motivation has been so influential as Abraham Maslow's hierarchy of needs enumerated in the U.S.A in 1943 in his paper 'A Theory of Motivation.' In essence, it suggests that a person is not motivated by mere external motive such as rewards or punishment but by an inner programme of human needs. These needs are arranged in sets of steps. When one set is satisfied, another set comes into play . A satisfied need ceases to motivate. Maslow organised human needs into a hierarchy of relative prepotency. Self Actualisation Sofety Physiological Hunger. Thirst, Sleep Security, Protection from Danger Social Esteem Belonging. Acceptance, Social life. Friendship Love; Affection Self Respect, Achievement. Status, Recognition [871 Growth Accomplishment, Personal Development Professor Maslow, in 1950 explained his concept of the "Self Actualising Man" further in his paper Self Actualising People: A study c f Psychological Health. "'Even, if all these needs are satisfied", wrote Prof; Maslow "We may still often (if not always) expect that a new disconten and restlessness will soon develop, unless the individual is doing what he is fitted for, A musician must compose music, an artist must paint, a poe~ must write, if he is to be ultimately in peace with himself. What a man car be. he must be. This need we may call self actualisation". Maslow defined self actualisation as "man's desire for self-fulfillment, namely to tend for him to become actualised in what he is potentially…..the desire to become more and more what one is, to become every thing that one is capable of becoming. The clear emergence of these needs usually rests upon prior satisfaction of the physiological, safety, love and esteem needs". This is exactly where blood donor motivator should decide : • Who of motivation? • What of motivation? • Why of motivation? • When of motivation? • Where of motivation? but at the same time by keeping things simple. The blood donor motivators have to bear in mind that there is a driving force as well as a restoring force as according to Newton's Law, all bodies tend to remain in a state of rest or of uniform motion in a straight line unless acted upon by a force. The force can promote a change but again according to Newton's Law: for every action there is an equal and opposite reaction. There will always be factors which will resist change and need to be neutralised according to the land, people and culture. In 1959, Fredrick Herzberg, an American Professor of Psychology published his research work in a book "The Motivation to Work". Herzberg established two separate sets of factors which influence motivation. Prior to this, people assumed that motivation and lack of motivation were opposite of one factor on a continuum. Herzberg upset the traditional view by stating that certain job factors primarily dissatisfy people when the conditions are absent. But their presence brings people to a satisfied neutral state. The presence of these factors does not motivate automatically but absence acts in demotivation. He called these potent dissatisfactory factors as Hygiene Factors or Maintenance Factors because they are necessary to maintain a reasonable level of satisfaction in people. Herzberg [88] identified some components of job satisfaction which motivates people. He labelled these factors as Motivation Factors. Examples of Maintenance Factors are : • Policies of organisation • Quality of supervision • Working condition • Status and inter personal relationship. Examples of Motivation Factors are : • Achievement • Recognition • Advancement • Work itself • Responsibilities This theory is known as Herzberg's Two Factor Theory. Donor motivators have to find out the factors promoting people to donate or not to donate blood or dropping out after the maiden donation. Another widely accepted approach of motivation is the "Expectancy Theory" developed by Prof. Victor H Vroom. Vroom explained that motivation is a product of how much one wants something and one's estimate of probability that a certain action will lead to it. He used the formula: Valence' X Expectancy', = Motivation (Strength of. (Probability of (Strength of desire one's desire for getting it with a towards action) . something) certain action) In short, all want is aimed at satisfaction of some order. This satisfaction may be extrinsic or intrinsic. This motivation often springs from the want. The want may be for love or recognition to derive satisfaction. [89] This theory was further expanded on the assumption that WE ALL HAVE WANT. Level of want X Expectancy Motivation Action Result Satisfaction From these premises, blood donor motivation can be defined as a force or a process which causes non-donors to donate blood on their own desire without any compulsion. Thus blood donor motivation means; • Encourage, inspire and stimulate people to donate blood • Provide reason and logic to donate blood • Develop desire to solve a social problem • Instil pride for blood donation. It has to be accepted that 50% of such motivation comes from within and 50% from the environment. There may be two types of motivation: • Attitude Motivation • Incentive Motivation. Blood donor motivation essentially aims at attitude motivation; incentive motivation would not ensure good quality of blood. Laws of Motivation can be summed up as: • Only the motivated can motivate • Motivation requires goal, recognition, challenge, participation and group belongings. • Motivation once achieved may not last for ever. • Motivation is an ongoing process • Progressing motivates • Everybody can be motivated. [90] Thus, motivation to donate blood involves several distinct steps or processes. It requires first an awareness of the need for blood. This requires education. Awareness about the need is an external part of donor motivation but awareness alone is not sufficient to cause people actually to donate blood. The motivation requires interest in the idea of donating blood voluntarily to save a life. Interest is an outgrowth of awareness. It develops over time, with the family or among friends, in school or in work place through discussion and reconsideration over and over again. It is a small group function and not totally a function of the public or mass. Interest alone does not lead people to donate blood. It is however an essential step in the process of motivation towards commitment to donate blood voluntarily without coercion whatsoever. Motivation implies that the person has a desire to donate blood. This desire is found only in people who have already been made aware and interested. The role of the blood transfusion service is to harness the strength of networks of donor groups or donor organisations in the country. The desire to donate blood may also come in a disorganised fashion through a family crisis or national calamity or disaster or even battle or war. This is a normal human instinct and reaction. The donor motivators and blood transfusion service can utilise this human reaction in a constructive manner. However, it is not sufficient to rely upon such causes to meet the daily need. Even the desire to donate blood will not without necessary organisation to channel the desire motivation of the blood transfusion service as a voluntary blood programme for the country. The essential point is that blood process needing education, organisation transparencies and credibility of blood transfusion service. donor with lead to blood donation into action. This needs whole to achieve total motivation good is a continuous planning, perfect All these will not happen without continuous effort of blood donor motivators and transfusion service in an organised form as the saying goes Together Every One Achieves More (TEAM) to build awareness and creation of interest and desire to act. [91] Principles of Donor Recruitment A blood bank with a beautiful building, well equipped and trained staff .sophisticated modern equipment and techniques, blood collection vans, kits, reagents, chemicals and glow sign cannot serve the ailing patients unless it has adequate blood. For safe blood transfusion good quality of blood is needed. To ensure quality, voluntary blood donors are to be recruited and voluntary blood donors base has to be built up in the community to keep the blood bank shelves full all the time, It is accepted all over the world that blood donors are microscopic minority in any community, be it industrial, developed, developing or backward country; although in every society there are enough people capable of donating blood. • • The chief reasons for not donating blood all over the world are: Fear complex Nobody approached people to donate blood. Therefore, donor recruiting is a demanding task. This is a continuous process with newer innovation with time. Pragmatic programmes suitable for land and the people based on rational principles have to be formulated. There are two models in vogue in different countries: One is: • Publicity • Propaganda • Enticement. • • • • Second one is: Education Motivation Donation in camp Recognition of donor. Some of the countries have taken coercive or compulsive method which should not be taken into consideration in democratic countries like India. We have to choose between the two for the country/region/state. Many donor recruitment programmes overemphasise audio-visual publicity through poster, newspaper, radio and TV announcements. Without a thorough organisational process to reach the donors individually or in groups, these publicity techniques in Indian context have not recruited [92] sufficient donors. The publicity may have a reinforcement effect. But this cannot be the prime principle. Propaganda of blood shortage in blood banks and consequent appeal for blood donation send a wrong message. This propaganda gives impression that blood transfusion service is failing in its mission. These appeals have never been productive. Donor recruitment is the process that includes public motivation, identification and recruitment of donor groups; education and motivation of donor recruiters, donor groups and individual donor: organisation and scheduling of blood collection sessions; maintenance of records of donors and donor groups; development and maintenance of comprehensive programme for retention of known donors; maintenance and analysis of statistics and recognition of the contribution of individual donor and donor groups for the cause. Thus, motivation to donate blood involves several distinct processes. It requires first an awareness about the need of blood and then an awareness that there is no harm in donating blood. Desire to donate blood may come in organised or unorganised manner through the process of being asked by somebody, normally a blood donor motivator. It seldom comes from publicity or public appeal as all these are too impersonal to motivate an individual to take action. Even the desire to donate blood must be channelled into action, that is, by organising blood donation camps. Encouragement to donors e.g. pinning a lapel pin or awarding a certificate helps in recognition of donor. A person can donate blood 168 times between the age of 18 and 60 years. So a donor has to be retained and converted to a regular donor as this is a tested blood and can ensure safe blood transfusion. Thus, in the Indian context, the principles Education, Motivation, Donation in Camp, Recognition of Donor should be followed. Motivation of the whole population is necessary if the country is to ‘succeed in collecting requisite quantity of blood from the voluntary blood donors. This challenging task requires indepth knowledge of the land and people, their attitude and common behavioural pattern. Before a public education programme can be planned, knowledge must be available of the current understanding, attitudes and taboos within the community. [93] The principles of donor recruitment may be short term i.e. to recruit: donors to meet the immediate blood need. But without any long tern, planning to recruit donors of tomorrow, a culture of voluntary blood donation in the community cannot be developed. Thus, short term and long term programmes should go hand in hand. The approach to the community can be: • Individual Approach • Group Approach • Mass Approach. Again, mass approach is impersonal and costly. Besides proper feed back cannot be obtained. The result is not proportional to the effort put in and expenses incurred. So in the Indian context combination of Individual approach and Group approach may be considered as pragmatic and ideal — individual approach for the leader or influential member of the group and group approach for the group as a whole. SOME MYTHS RELATED TO BLOOD DONATION IN INDIA Blood donation Causes weakness or fatigue. Donating blood disturbs the balance of the body. It may Cause weight gain. Fear of transmission of foreign genes. Fear of the possibility of discovering some disease. Belief that a man who gives blood for his wife will die before she does. Fear that one who gives blood will not be able to have children. Belief that one will become a blood relative of the spouse. “If you have a Rupee and I have another, and we exchange, we have one Rupee each. But if you have a better idea and I have another and we exchange, we have two better ideas each. Ideas are more powerful than weapons”. -Anon [94] Donor Recruitment Strategies Many techniques of blood donor recruitment have been advocated. The best methods are understandably based on personal contact between motivator and prospective donor or at least contacts between motivator and group. Person to person contact may be difficult. But person to group contact is pragmatic. The transfusion service must get steady flow of blood to keep their shelves full all the year round. Some group or other should organise blood collection drive throughout the year. Group approach being considered as most pragmatic and effective approach to recruit donors as a short term strategy, the community may be divided into various target groups that may be approached during their convenient period. The groups may be: • Educational Institutions • Industrial and Commercial Organisations • Social and Cultural Organisations • Religious Orders • Political Organisations • Trade Unions • Fan Clubs • Govt. Organisations • Sports and Recreational Clubs and Organisations • Women’s Organisations • Medical Organisations/Institutions • Uniformed Services. Each group may be encouraged to select a suitable day for its blood collection drive. Every organisation likes to associate its blood donation day with significant day. The significant days may be International, National, Regional or even Local for the particular organisation. With a little library work and stretching of imagination, a calendar may be drawn up whereby every day can be found to be a significant day for some group or the other. Some such dates are listed in the Annexure IX. When a group of dreamers with conviction of purpose and a plan to act unite, an organisation is born. On the strength of such an organisation social change depends. The status of voluntary blood donation movement in different countries of the world and even among the states of this vast [95] country bear testimony to the strength, weakness or presence of such organisations. In 1947, India achieved independence. But before 1964, Independence Day was never observed by donating blood. The accident to Nari Contractor dates back to 1962. But Nari Contractor inaugurated the blood donation camp at Calcutta only in 1981 by donating blood in memory of Sir Frank Worrell for the first time anywhere in the world. It is the imagination which is needed in the motivation, recruitment and retention of blood donors. The motivator may approach the leader or the key person of the group and after convincing him or her. sits with the group for a motivational session using display materials and or flip charts. After the talk or discussion there should be question and answer session followed by distribution of some take-home materials like folder or booklet containing basic information on blood and blood donation. In the motivation session a suitable date for blood collection drive may be chosen. The gap between the motivation session and the date of blood donation drive should not be normally more than seven days. The key personnel of the group should be provided with posters/folders/stickers and encouraged to launch campaign locally. If a suitable date for the group is fixed and efforts are made by the motivators to induce the group to hold the camp in and around the date for 3/4 years then the blood collection drive becomes a regular activity of the group. The print and electronic media may be used to publicise the blood collection drive so that the group feels important. Handing over blood group-cum-donors card to the donors in due time helps in sustaining the blood donation by the group for years to come Weekdays are most suitable for educational institutions, industrial and commercial houses, trade unions, government organisation, uniformed organisations. Sundays and holidays are suitable for clubs and other groups Short Term Methods Any programme supporting and helping to propagate the message of particular blood collection drive is a short term strategy which may include seminars, talks, meetings, poster, banner, hoarding, leaflet, radio, TV newspaper announcements and reporting. [96] Long Term Methods Any donor recruitment strategy meant for recruiting donors of tomorrow may be considered as long term strategy. These include walk, rally, hoarding, articles in print media and general awareness programme to inform and educate common people. School education programme, incorporation of lessons in school text book, demonstration of blood donation camps in schools are the methods for recruiting donors of tomorrow. Converting blood donors and young adults to honorary donor recruiters through structured training programme to spread the message of blood donation deep down in the community helps building up a healthy people’s movement. After successful school education programme the school may be encouraged to organise blood donation camps with teachers, parents, ex-students and people of the locality as donors and the children as organisers and motivators. The children able to motivate their parents and relatives to donate blood in the camp organised at their school may be presented with a badge with inscription like “I am proud. There is blood donor in my family” Mass blood donation camps after a general awareness campaign by bringing in a number of blood banks to work side by side and pre-donation announcements and post-donation reporting are also considered as long term strategies as these camps help in spreading of the message of voluntary blood donation in the community, which in turn helps in organising smaller camps throughout the year. On one occasion there can be a number of camps in different places concurrently. The quiz contest, debate, elocution contest, sit and draw contest, slogan contest, essay contest on blood and blood donation are also part of long term strategies. Direct method The most common methods employed generally are lectures / discussions / seminar / symposia / group-meetings, etc. These are particularly applied to organised target groups like industrial and commercial establishments, dubs or locality based organisations, schools and colleges as also for organised professional bodies like those of medical professionals, Paramedicals, nurses, teachers and those of sportsmen, intellectuals, performing artists and the like. The areas covered in such talks include: • brief history of blood donation movement and blood transfusion, • present status of blood transfusion service of the region, • indications of blood transfusion, as a life saving measure, [97] • blood requirement of the region vis-a-vis availability and their source, • evils of blood procured from commercial sources, • eligibility of the donor, • actual ‘material loss’ after donation and recuperation thereof • advantages of blood donation. • importance of safe blood donation, • blood donation as safe procedure • possible role of the target audience in this regard, • an appeal to participate in the movement. In conclusion, some time should always be made available for a question and answer session. Indirect methods • • • • • • • • • • • The common but useful method applied for group or community motivation is by way of putting up of banners, display hoardings posters, etc. in public places and distribution of leaflets and handouts. Puppet shows, drama, songs and poems with the theme of blood donation. Presentation of badge, lapel pin, watch-sticker (depicting blood group), awarding certificate in public ceremonies to help motivate the non-donor general public. Occasionally such awards is modelled to have a special appeal to a particular group of donors. Impressive thanks letter addressed to the donor to generate lasting warmth and to induce the donor to repeat the act of donation, Group recognition like inter-institution / inter-class / inter-club trophies are awarded for mobilising maximum number of blood donors. Organisation of ‘Know your blood group’ stall decorated with colourful slogans, posters and allied visuals at fairs, exhibitions. festival pandals etc. accompanied by short talks and distribution of leaflets. Short-film show and skit on the theme of blood donation. Display of cinema slides and mobile audio-visual campaigns. Use of mass-media like news papers, periodicals, Radio and TV. Debate, poster, quiz and slogan competitions. Distribution of special donor-badge for multiple donations, e.g. 5/10/25/50/100 times. Printing of blood donation slogans on hospital outdoor ticket. bill presented by Electricity / Water board / Treasury, Premium [98] notices and receipts of LIC, Milk pouch or Food packing, Postal cancellations, etc. • Introduction of national / state level awards for donor organisations. • Appeals from religious leaders to their followers and general public. Supplementary methods • Motivation of the blood users, i.e., medical professional, paramedicals and nurses as well as those in the administration who run the service. • Laying stress on the importance of a well-organised and standadised blood transfusion service as part of the national health care service. • Emphasis on avoidance of injudicious use of blood. • Impressing upon the blood bank personnel the need to be courteous in approach to the donors. • Introduction of comprehensive in-service training of blood bank staff for the updating of their knowledge and skill. • Pleasant housing for blood banks and appropriate collection apparatus to impress the donors. • Strict donor-screening according to the standard norms to instil confidence in the donors. In donor recruitment ideas and imagination play a great role to boost up blood donation movement. Technique to Meet Rare and Fresh Blood Need With the advancement of technology of open-heart surgery in the hospitals of the country, the people irrespective of social and financial status are haunting donor motivators and social welfare organisations in this field, in quest of blood donors to meet their fresh blood need (i.e., blood of a donor bled on the date of the elective surgery). The people, otherwise willing to donate blood in camps, are reluctant to donate blood in such cases to the dictate of surgeons and according to the administrative and managerial balance of convenience of the blood banks. These blood needs put the regular donors under pressure over and over again. Motivators may try the following pre-tested method: [99] At least fifteen days before these elective surgeries, motivational sessions are organised either at the place of work of the patient or next of his/her kin or at the locality of the patient. The science of blood and blood donation is explained vis-a-vis the blood need of the particular patient. The blood groupings of the willing donors are carried out on the spot. The simplicity of the procedure often prompts the onlookers to volunteer. A short list of donors of the right group is then prepared and handed over to the patient or his/her relative to escort the donors to the hospital on the day, of elective surgery. Such donors in their locality or place of work are considered as heroes as the patient is known to all of them. There is no magic formula for success in donor recruitment and success is not automatically guaranteed unless backed by hard work, sincerity, dedication, conviction and imagination. [100] School Education Programme An ideal blood donor recruitment programme to ensure a blood transfusion service for the country entirely depending on real total voluntary blood donation must have two concurrent strategies: (i) short term strategies to meet the need of today as far as possible and (ii) long term strategies to meet the need of tomorrow or day after tomorrow. There are programme for donors of tomorrow in Australia, Portugal. France, USA, Zimbabwe and India. Each one is culture specific of the country. A pretested programme of a particular region of India is being suggested for the whole country. This is. in fact, a class room teaching by the trained volunteers / staff from blood bank or voluntary organisation. The programme should be in the form of extension lecture and should not be a passing head of examination. Lecture Plan I. Title of the Lecture : Blood and Blood Donation II. Entry behaviour Students of age group between 13 and 16 years who normally study “Human Blood” in their Life Science/Biology curriculum in school. III. • • • Object To inspire students to donate blood on attaining the age of 18. To explain the need of knowing one’s own blood group. To impress upon the students the danger of transfusing blood collected from blood sellers and commercialisation of human blood. IV. Teaching Aids Chalk, duster, chalk board, flip chart, poster, models, polybag, leaflet, folder and booklet. V. Duration Not exceeding two periods (70 to 90 minutes) including time for question and answer. VI. Method Lecture, board work, demonstration followed by question and answer including general discussions. [101] VII. Concept to be imparted in a single lecture/talk/interaction Concept 1 - Importance and significance of the topic in the present society. Concept 2 - Importance of blood transfusion in modern medical science. Concept 3 - Who needs blood and when (indications of blood transfusion). Concept 4 - History of blood transfusion and blood banking. Concept 5 - Blood requirement of the state and its source of supply - statistics. Concept 6 - Reasons for shortage of blood for transfusion in the country (i.e. reasons for not donating blood). Concept 7 - There is no substitute for human blood. Concept 8 - Blood volume, volume of donation and time for recuperation - no special diet, rest or medicine necessary. Normal life of blood cells and shelf life of blood. Interval between two successive blood donations. Concept 9 - Blood is collected from vein - pain experienced in venipuncture during blood donation. Concept 10 - Who can donate blood (selection of blood donor)? Concept 11 - What do voluntary blood donors gel? Concept 12 - Blood group and importance of knowing one’s own blood group and inheritance of blood group. Concept 13 - Evils of commercialisation of human blood vis-a-vis professional blood sellers. Concept of safe blood transfusion in the days of blood communicable diseases. Concept 14 - Why should every eligible person donate blood? Concept 15 - hat can school students do? Concept 16 - Conclusion - One can donate blood on attaining the age of 18 years. (viii) Evaluation : Question and Answer and Quiz Competition. [102] (ix) Exit behaviour; Students are motivated to donate blood on attaining the age of 18 years. Methodology The classroom may be decorated with attractive colourful posters with visuals and message of voluntary blood donation. The lecture should be supple merited by board work and flip charts. The selected stories from the epics, literature, history and everyday life are to be used as the vehicle of oral communication of message and science along with simile, metaphor, allegory and parable to keep a mark on the young mind to act later, even after five years. Attractive printed materials communicating messages of blood donation with visuals like class routine (timetable) / folder / booklet / card may be presented to every student at the end of the class to carry home and retain as memento. Evaluation After effective interactions students would normally be able to answer the following questions by spontaneous raise of hands. • Would you donate blood on attaining the age of 18 years? • Can you calculate your own blood volume? How much surplus blood you have in your body? How much blood you can part with without causing any harm to yourself? • Will you buy blood from commercial blood sellers? Inter-school quiz contests can be organised on Blood and Blood Donation as a follow up action. Follow-up by Short Term Programme Wherever teachers of the school or head of the institution and students will be interested to organise a blood collection drive as a part of their community service or social service programme, a blood donation camp may be organised in the school premises on a subsequent convenient date where school students of tender age become organisers, motivators and recruiters with teachers, guardians and ex-students as blood donors. Teachers’ Training The trainers/instructors/teachers of this programme are volunteers coming from different walks of life to extend their labour of love for the cause. They are to be trained/groomed/oriented in the oral communication and art of teaching through a series of workshops and other teachers training [103] programme. The teachers’ manual, teachers’ hand book and guide book ensure the uniformity of this teaching programme. The trained volunteer teachers should remember: • Indoctrination of the teenaged students with idealism of serving fellow human beings need be practised with conviction. • In every school 90 minutes time may not be available. When time is a constraint, the history of blood transfusion may be pruned and if necessary, may be omitted. • Use of medical terminology or jargon should be avoided as far as possible. • Concept of unit 8 and 10 being the means to remove fear complex, should not be curtailed or omitted. • Salient points should clearly be written on the board at d demonstrated by flip charts. A popular story used in School Education Programme School students forget the speaker but remember the story. in West Bengal. A NIGHT TO REMEMBER The majestic passenger liner Titanic’ on her maiden voyage with 2203 passenger and crew on board struck an iceberg while cruising through the Atlantic on the midnight of April 14, 1912. The blow was fatal for survival. SOS signals were sent out and the life-boats lowered. Captain Arthur Rostran of the SS Carpethia sailing in the opposite direction responded first. Within minutes the Captain altered the course and; covered a distance of 58 miles in 4 hours and picked up 763 survivors from the life boats. Another ship, the SS Californian, commanded by Captain Stanly Lord noticed the distress rockets fired from the Titanic from a distance of 19 miles, did not care to respond. His timely response could have saved all the lives, in all probability, because the distance of 19 miles could have been covered in 90 minutes at the most. The ‘Titanic’ was afloat for two and a half hours after the collision. Which Captain would be your idol of life? [104] Women in Blood Donation Movement Population-wise the men: women ratio is almost 50:50, blood donor-wise though the same would be about 95 : 05 in the country, whereas in the consumption of blood the ratio is again somewhat like 40 : 60. This would logically lead to the conclusion that in case of blood transfusion, women of our country are dependent on the men-folk. The task before the donor motivator is to inspire them and to win over their shyness. Both in physical and mental characteristics, women differ from men and these differences have determined their respective domains and roles in the society. Of course, today’s spokeswomen of “Women’s Lib” in their revolutionary flair often deny this fact outright. According to them, there is no difference of domains earmarked for the male or the female. Sociologists may engage in an unending debate on who is dominating whom or who wants to be dominated by the others and similar other issues. But what appears to us are that the elements to become a sister, to become a wife or to become mother is instilled in the very nature of women; but never to become a servant. Women posses more love and affection — otherwise the child would not have grown to manhood, the family would have toppled down. Mother nurtures the child out of sheer love, there is not obligation; wife serves the husband out of love and not as an obligation. Today, all over the world, women have come out to take their rightful position in the vast expanse of the world. Now, they have equal responsibility in the community of mankind. If they cannot discharge the same then it would be a matter of shame, a failure on their part. Such being the perspective, the women of contemporary India have to think over and over again, as to how best they may play their role, shoulder to shoulder with their male partners in the development of the country. Physiologically, the size of the heart of women is smaller; similarly their blood-volume is 66 ml/kg, of body weight as against 76 ml/kg for men. But in the social life, lion-hearted women outnumber the men, since they have the instinctive love to overcome gracefully tribulations and yet remain magnanimous. Once we reach this loving heart of women, the problem of donor recruitment would be solved. Women in any community may serve the transfusion service in more ways than one: by becoming a blood donor (which is the simplest way) and by educating their children to become blood donors on their attaining [105] adulthood (which is a more far-reaching way}. Women are in an advantageous position to eradicate the superstitions and taboos from the minds of their children. Once the child is allowed and trained to think free, there is less chance of confused thinking later on. Emotionally, women are more receptive. One may try to motivate the students in any coeducational college to vouch for this. Listening to the same talk on the story of blood and blood transfusion, girls would respond more than boys in registering their readiness to donate blood. Has anyone ever come across an instance where a sister has refused to donate blood for the need of her brother or a mother refusing to donate for her son or daughter? There is no example of ladies of rare group empaneled who have to serve as on call donors refusing to respond to donate blood for a newborn baby. This is unimaginable. May be, shyness and fear initially stand in the way, but once they are made to understand what is what, their readiness is exemplary. West Bengal’s experience of ‘Florence Nightingale Day’, when nursing sisters of all the Nursing Schools of West Bengal hospitals donate blood every year, is yet another example of women’s response to the call of the ailing fraternity. Similar is the experience with women’s colleges. Indian women are generally shy in nature. Donating blood in the open camps exposed to the public eye often acts as a hindrance to their willingness. In any assembly of women they behave more freely as may be seen in camps organised on the occasion of International Women’s Day and in camps organised at women’s colleges. Use of draw sheets for female blood donor in a camp is a must. In fine, women should not forget that they require quite a large quantity of blood in treatment of various surgical cases and particularly at child-birth. So they have an obligation to donate back. However, where women are concerned, the question of obligation need not arise at all. They will be ready to donate out of sheer love and ‘love without obligation is heavenly’. To motivate women-folk to donate blood would be the task of the donor motivators. Motivators should remember the maxim: “If you can educate a man. you educate a person. If you can educate a woman, you educate a whole family”. Let us remember that women are the mothers of the human race. [106] Blood Donation Camp Voluntary blood donation programmes - recruitment and retention are about people and community, about understanding them, capturing their interest and influencing their behaviour. The main communicating task for both blood donor recruitment and retention should be geared towards getting public understanding about the importance and triggering a response for action. Once a blood donor motivator raises awareness, he or she must motivate and persuade people to donate blood. One key secret of successful blood donor recruitment is to take the beds to the donors as close as possible on their convenient date and time rather than expecting the donors to come to the blood bank. The closer the bed to the potential donor, the stronger is the likelihood of success. This is possible only through outdoor blood donation camps. If the camps are held in a relaxed manner, it can be an enjoyable pleasant experience for all concerned. All over the world, most blood from voluntary blood donors is collected from outdoor camps in rural and urban areas. In Indian context camps can be organised on holidays or in the evening in residential area or locality based socio-cultural organisations not only in cities or towns, but also in suburbs and villages. The people of all ages assemble either on holidays or at the end of day’s or week’s work and the example of adults donating blood would be a strong teaching and demonstration effect for the children. Even diehard determined non-donors may be expected to donate blood someday if the camps become a regular activity in a particular venue. Camps can be organised in educational institutions, industrial and commercial houses throughout the week. Only all these combined efforts would ensure steady flow of blood in the blood banks. A few blood banks have well equipped mobile blood collection vans fitted with everything including beds, doctor’s chair, wash basin, storage refrigerator and even a small refreshment corner with own power generating unit. These vans are quite costly and cannot negotiate through the roads in suburban areas and villages and are not suitable for mass blood donation camps even in camps with 200 donors. Besides, festive mood of the environment and demonstration effect would not be there. [107] So in Indian context, best method is outdoor camps by carrying blood bank personnel and equipment in a vehicle and pitching the camp in a prefixed well ventilated place. The outdoor camps in India are and will be organised in places fa away from blood banks. So a checklist of blood collection equipment and instruments should be maintained and carefully checked before the departure of the vehicle from the blood bank. Most of the blood collection items cannot be organised locally. Any omission to carry even a small item may frustrate the noble effort of the donor organisers and the donors. • • • • • • • • Advantages of collection of blood from camps: Intending donors get opportunity to donate according to their convenience. Familiar faces and known atmosphere help in the shedding of fear complex by the first time donors. Community participation. Recruits new donors. Health status and habits of intending blood donors are known to organisers, quality blood is assured due to self exclusion. Demonstration effect. Convert non-donor to donor. Help in donor retention. In camp management and organisation, local organisers have scope of using their imagination to convert the area to a festive mood with decoration, light music rather than the silence inside a hospital blood bank. The motivator should identify a key person amongst the group. In consultation with the key person, motivation session and the date and time of the camp should be fixed up according to the convenience of the donor group. The proposed camp site should be inspected well due importance to the following points: • Adequacy of the space for anticipated number of donors and on-lookers • Lighting and ventilation • Electrical outfits • Availability of water • Toilet facilities • Waiting space • Donors’ screening space • Furniture (tables and chairs) [108] in advance with • • Refreshment space not far away from the donors’ beds Cleanliness of the site. Movement of the donor in the camp should be as far as possible unidirectional. Flow diagram of donor may be as hereunder; Intending donor Reception Filling in Registration card Checking Body weight Registration Haemoglobin Estimation Medical Check up Medical Questionnaire Blood donation and rest in Refreshment and rest Recognition of donor by badge and certificate Hearty send off Donor On the day of the camp, the chief motivators and the team of volunteers and the blood bank team should reach in time. The donors should be warmly received and guided and escorted through different stages. Presentation of memento, badge, certificate with courtesy and sincerity and answering all queries of donor should be considered as part of donor motivation. The refreshment corner should be well managed and donors should be handled with personal human touch. This being the last point of the camp, it leaves a permanent impression in the mind of the donors. Talking with the donor throughout all the stages is extremely important, as it helps donors to feel wanted and also helps the first time donors to shed their fear. The donors should be advised to remain in refreshment room for at least 15 minutes and should be advised to increase their water consumption I during the day and refrain from smoking for half an hour. A hearty good-bye with a request to donate again after three months is destined to inspire a donor to become a regular repeat donor. Signs of minor reaction like the following should be handled with tender loving care and compassion : • Restlessness • Perspiration on forehead • Pale colour • Lack of willingness to communicate [109] • • Nervous glances Tendency to faint. When reaction occurs to a donor, motivator or medico-social work should remain calm and try not to get other donors upset and call in the medical officer-in-charge of the blood collection team, but ensuring the prevention of the donor from falling down. Placing the donor in the bed or floor with a pillow under the feet, helps in subsiding minor reactions. But doctors should check up the donor in all such cases. In case of bleeding from the seal of venipuncture, finger pressure with cotton wool, folding the arm with a cotton wool pad in between and raising the folded hand a little upward helps in stopping such bleeding. Once the bleeding stops, the venipuncture site may be sealed again. The best motivational efforts may go in vain, in spite of best possible donor recruitment and retention strategies, if the camps are not organised in an efficient manner with active involvement of blood bank team, local organiser and motivators. At every stage, care should be taken so that the donor can leave the area with a good impression with a resolution to come back again. Donors’ blood cards should be made available to the donors in time directly or through their local organisers. Refreshment should be offered neatly with a friendly gesture and hospitality. The motivators should understand the significance of serving refreshment to keep the donor engaged under the watchful eyes of socio-medical volunteers or the medical officer. The donor should be made to understand that refreshment has nothing to do with immediate recuperation of blood loss due to donation. A piping hot or cold drink and light refreshment are offered to compel the donor to spend some time in a relaxed mood. Whatever be the items of refreshment, they should be served neatly and nicely with a smile. A well organised camp inspires many onlookers around to become blood donors. Blood Donation Camp Premises The premises used for outdoor donor sessions may often be the only local venue available, but they must be of sufficient size, suitable construction and in an appropriate location to allow proper operation. They must be clean and maintained in accordance with accepted rules of hygiene. [110] Space Requirement The space required will obviously depend on the number of staff and donors and the rate at which donors arrive. The following activities should be kept in mind when accepting a venue. • Registration of donors and all other necessary information processing. Wherever possible, there should be easy access to a telephone, preferably within the venue. • Pre-donation counselling, the medical history and the health check-up to determine donors’ fitness to donate blood. Facilities should be available for confidential discussions between donors and social workers or the medical officer. • Withdrawal of blood from donors without risk of contamination or errors. Visitors and onlookers should not be allowed to come too close to the bleeding area. • The social and medical care of donors, including those who suffer adverse reactions. Sufficient seating arrangements should be provided for donors and staff, with allowance made for possible queues during busy periods. • Storage of equipment, reagents and disposable. Health and Safety Health and safety factors should be taken into account when selecting venues for outdoor camps. In particular, the following points should be kept in mind: • The venue should be as close as possible to the centre of population being served. It should be possible for the vehicle to park close to the access doors in order to facilitate the unloading of equipment. The ground to be covered by staff carrying equipment into the building should be even and well-lit, if possible, the space to be used should not require the carrying of equipment on stairs. A similar safe approach to the building should be ensured for donors. Notices should be displayed directing donors to the appropriate entrance to the building and to the room being used. • The place should be free from dust as far as practicable. Cement floor with appropriate matting would be helpful. • The furniture and equipment should be arranged within the available space to minimise crowding (for avoiding possibility of mistakes or accidents), enabling privacy and adequate supervision to be maintained and ensuring a smooth and logical work-flow. • There should be adequate lighting for all the required activities. Wherever possible, there should be provision for the use of [111] • • • • • • emergency lighting in the event of a power-cut. The blood collection team should always carry a hunter’s torch. It may not be possible for the collection team to control the temperature, but every effort should be made to ensure that the space does not become too hot. too cold or stuffy and must be comfortable. There should be arrangement for fans in summer. Facilities for providing refreshments for donors and staff should be separate from other activities, wherever possible. Every effort should be made to ensure that equipment used in this area does not pose a safety hazard. Toilet facilities for male and female donors and staff should be available. Separate washing facilities are desirable for staff. Adequate facilities should be available for .the safe disposal of waste. Sharp and solid waste should be collected in suitable containers for return to the blood transfusion centre or blood bank and for subsequent safe disposal. The premises should be free from vermin. Proper arrangements should be made for cold chain maintenance. Mass Blood Donation Camp In industrial or commercial houses and educational institutions, facilities for holding blood donation camps may be extended once in a year by suspending their normal activities. If smaller blood banks opt to collect blood according to their need or capacity many willing donors have to be refused. This may send a wrong signal to the community and would certainly make the task of the donor organisers a difficult one. as they would not be able to make such make-shift arrangement for camps again at successive intervals. The organisations may not like to suspend their normal work for the camp in the same year once again. Camps at such a place organised by massive awareness campaign, particularly when the camp is organised at a central place where donors come individually by availing themselves of public transport, should be planned in a different way as refusal to accept from such donors on account of logistics may affect the blood donation movement to a considerable extent. Besides large scale awareness campaign through electronic or print media is not possible for smaller camps of 20/50 blood donors. The solution lies in bringing in a number of blood bank teams to work side by side under the same roof, each collecting blood according to its respective capacity. Donor screening, registration and donors refreshment corner may be arranged for centrally so also the campaign. [112] There have been such successful mass blood donation camps in the cities like Delhi. Calcutta, Mumbai. Chennai, Surat, Bangalore, and Pune. Some such camps have become regular fixed day camps of over twenty years’ standing. Many donors of these mass donation camps have subsequently become organisers of smaller camps in their place of work or in their locality. There are three main advantages derived from a mass donation camp. First the resources available with any voluntary agency in India are just not sufficient to sustain a mass awareness campaign round the year .However, a specific campaign can start about three weeks before a mass donation camp and can gradually build up into a crescendo through postering, outdoor hoardings, radio talks, TV. exposures and through the free coverage in the newspapers. The publicity generated leads to increased awareness in general. Secondly, mass camps have a demonstration effect. When one sees so many fellow human beings donating blood, he feels inadequate unless he also donates himself. This is the demonstration effect of peer pressure. The third benefit is that a number of big and’ small blood banks working side by side act as a technical workshop and activate the less active blood banks. This, of course, needs a competent technical supervision. Mass blood donation camps call for very well coordinated organised efforts between the organisers, the collecting agency and above all, the donors. A well managed mass blood donation camp can motivate the non-donors and a reminder to repeat the act may also become instrumental in ensuring better participation on subsequent occasions. Mass blood donation camps also open up opportunities to involve more blood bank personnel, social organisations and volunteers with the blood donation movement. Such camps may be organised in educational institutions, factories, big offices, banks, social clubs or at central convenient places where donors being motivated through campaign may come individually. Precaution should always be taken so that quality is not sacrificed for the sake of quantity. All technical procedures should be strictly adhered to. In mass blood donation camp poor turnout due to natural calamity or situation beyond the control of the organisers may frustrate the elaborate arrangement. So the organisers should be pragmatic and not over ambitious while planning such camps. [113] Mass Blood Donation Camp 114 Mega blood donation camps of India [115] Donor Counselling and Care The recruitment of blood donors (and retention of them as a sustained regular activity based on systematic and scientific manner) is not merely a combination of education, motivation, donation and recognition but includes donor counselling and donor care. Donor counselling starts from the motivational and educational sessions for motivating and recruiting donors. The chief reasons for not donating blood by the majority are fear complex, social taboo and age-old superstition. Therefore, pre-donation counselling in the motivational session; should aim at eliminating fear complex through information and education This should include blood need for transfusion in the region, indication of blood transfusion, harmlessness of blood donation, blood volume in human body, amount of surplus, amount of donation, recuperative power of human body, principles of donor selection, blood communicable diseases, safe blood transfusion, safety of blood donor, safety of recipient and need of self exclusion by the intending donors when one is not fit to donate blood Techniques are oral communication supported by display materials and distribution of short attractive reading materials in readers’ friendly language Pre-donation counselling is essential for ensuring safe blood supply because lack of education and awareness aggravates problems of transfusion transmitted infections. The objectives of pre-donation counselling are: • To increase donor awareness - of transfusion transmissible infection, route of transmission and prevention. - of that the donated blood would be tested. - of the implication and possible consequences of that process. • To discourage blood donations - by self-deferral of people coming only for testing. - among people who may have history of risk. Pre-donation counselling should be provided before donation in private area maintaining confidentiality and stressing the need for hones; and truthful reply, explaining the need of selfdeferral when history of pas: ailments or recent risk history so demands. [116] A prospective donor, motivated through the above, arrives at the site of blood donation. His/her first impression is of paramount importance. The reception should instill a sense of confidence. Quick, efficient and to the point handling of a donor right from the entry of the donor till departure from the donation spot are considered as a part of donor care and donor retention. Punctuality is considered as a virtue. To the donor, his/her time is important. Unnecessary waiting would put the donor off for ever. Scientific donor screening with tender loving care is an indicator of donor care and creates in the donor a sense of satisfaction and feeling of safety of donation. Giving company to donor and escorting donor upto bed are part of care. During donation, all operations are keenly observed by the critical eyes of the donor. Talking to the donor, answering to all questions to satisfy the curiosity of donors, clean atmosphere, a few words of confidence add credence to the blood collection team. Care should be taken to avoid haematomas, bruises or double puncture of vein. The donor has to be persuaded to rest in bed or in a couch for the prescribed period. Any short cut for quick disposal of donors should be avoided. Pinning of the voluntary donor badge at the end of the donation by the social worker and a smiling “thank you” before the donor leaves the bed, pay enormous dividends to retain donors. The donor should be escorted to the refreshment corner which must have a cheerful look. Food and drinks should be served neatly and cordially with a smile. Giving company and advising about do’s and don’ts for the next few hours are part of donor care. A hearty “good bye” with a request to donate again after three months is part of donor counselling and care. In the post donation stage, handing over of donor certificate and blood donor cards to respective donor in the shortest possible time should be considered as part of donor care so that the donor in case of first donation can know his/her blood group. The blood group should be carefully determined and cards and certificates should be neatly prepared. Indicating wrong blood group to repeat donors may deter them from donating again resulting in loss of motivated persons. The donor has a right to know everything about blood, blood donation and blood transfusion service. Motivators and social workers should equip themselves to answer questions in an easy-to-understand language which should include, apart from the science of blood donation, blood group, its [117] determination and inheritance or procedure of getting blood from blood bank in time of need. Post-donation counselling in case of positive test results can be undertaken by very senior trained staff confidentially, only after confirmatory tests, about future requirement, treatment and follow-up facilities with dos and donts. In case of negative test results, post donation counselling whenever possible may be undertaken on: • Need to know about window period. • How to remain safe blood donor • Need for safe blood donor base. • How to be a regular donor. Proper counselling and care of donors with courtesy, concern, care and sincerity may inspire many onlookers and potential donors to become blood donors for the first time and one time donors to become regular donors to strengthen the healthy donor base. Prevention reinforced Stage 1 Stage 1 PrePre- donation donation information information Self-Deferral Self-Deferral Stage 2 Stage 2 PrePre-donation donationcounseling counseling physical physical check check and and selsction selsction Deferral/Self-Deferral Deferral/Self-Deferral Stage 3 Stage 3 Blood Blood donation donation andand testing testing Positive/Equivocal Repeat test test on new on new sample sample NegativeNegative Negative Stage 4 Stage 4 Positive/Equivocal Positive/EquivocalPostPostdonation donation counseling counseling and/orand/or referred referred Stage 4 Stage 4 Post- donation Post- donation information information and/or and/or counselling counselling Health Healthcare careand andsupport support services services for testing for testing follow-up follow-up counseling counseling and/or care and/or care Recruit for regular donor Flow Chart of Stages in Blood Donor Counselling WHO [118] Serving refreshment to the donors is a part of donors’ care [119] Donor Recognition In the four principles of voluntary donor recruitment strategies, recognition of donor comes in line with the other three — Education, Motivation and Donation. Human beings value positive recognition — that precious moment when someone important expresses some real appreciation for what he/she has contributed. When one person knows that he/she has worked hard and has done something, should he/she not expect to be recognised for it? If it is not forthcoming from the team leader or colleagues in the team everybody tends to feel unhonoured, unvalued and unrecognised. The motivation drops, energy level falls and spirit evaporates. Therefore, recognition has a big role in motivation. Milton wrote: “Fame is the spur that the clear spirit doth raise To scorn delights, and Hue laborious days”. Where does recognition come from? It can have a variety of sources. In the case of a famous person, it is a matter of public esteem. Fame comes from the Latin word ‘fama’ meaning report. So fame is how people talk about a person which adds up to his/her personal reputation. A person who is much talked about favourably is a reputed person. Reputation based upon significant achievements make people famous. Of course, in our society, individuals can more easily achieve a kind of spurious fame by gaining the attention of many people for diverse reasons. A footballer, cricketer, television interviewer, pop singer can easily become famous in our society with the favour of media. Although, such fame carries positive overtones, it can simply suggest popularity or general recognition rather than discriminating approval or general recognition of inherent excellence. The media can, to a large extent, make or break this form of popularity or recognition. The vast majority of people, however, are not destined to become famous in the real sense of the word. Therefore, for most, recognition will be particular rather than general. Recognition for common people needs to come both formally and informally. There should be formal occasions when you recognise the quality or value of a particular contribution; be it of an individual or team effort. [120] There will also be plenty of informal opportunities for expressing appreciations. But recognition in both forms should have the following characteristics: • • • • • • Giving recognition should be on the principle of treating everyone in a fair and equal way. It should reward real achievement or contribution to the common good, not self-seeking gain. It should serve to inspire and encourage all concerned. Wherever possible, it should be given in a public way in front of the working group or organisation. Remember to treat recognition informally as well as formally. Above ail, it must be genuine and sincere or in a word, real. The last point is crucial. People dislike insincerity. In the hierarchy of human needs, recognition plays an important role in donor recruitment and retention. Recognition of the donors and enticement to recruit donors are not the same thing. In some developed countries attempts were made to entice donors with free hamburger or steak of McDonald or such other renowned outlets. Donors felt insulted as they thought their gift of love was being equated with hamburgers. Complaints were received over phone from some regular donors deploring attitude of persons needing such incentive. Paying health insurance premium for the donors is a monetary form of incentive and therefore, is not recommended. Recognition of voluntary blood donor means honour without any monetary value. Recognition of donors helps as: • Automatic incentive • Paramount impression • Social prestige • Motivation to panel donors • Healthy spirit of competition • Spurs donors to greater participation • Feeling appreciated and honoured • Forms stronger commitment • Help in retention of donors. • • • • Forms of Donor Recognition may be in the following form: Letter of appreciation Greetings cards / Thank you letters Certificate Badge [121] Certificates play a big role in Donor Recognition [122] • • • • • • ■ Memento Souvenir Annual felicitation by way of convocation Donors card Special award for 10/25/50/100 time donation Donors' get-together Honouring at a public function. 1' 0/25/50/100 donation award or badge at a public ceremony is a part of donor recognition. Recognition of donor organisations in the form of letters of appreciation, greetings cards for special occasions and by giving award/' souvenir/memento, etc. through public function is highly recommended. Although a voluntary donor does not expect anything in lieu of gift of love, yet a metal badge bearing the national emblem and marked voluntary donor and a certificate presented in the camp just after the donation in recognition of the donation help a long way in motivating people to donate blood. Blood group-cum-donors cards also help in the promotion of the blood donation movement. Special awards for multiple donations draw the attention of the society to this social cause and should be instituted for donors. Outstanding social workers, doctors, camp organisers may also be honoured and recognised. Inter organisation challenge trophies can build up a healthy competition among various groups. Within the state, a three-tier system of awards is recommended, i. e., local, district and state. There should be recognition of the services of the blood banks and donor motivating organisations by the appropriate authorities at all three levels. It is desirable that the performance of the state blood transfusion service should be evaluated against a predetermined norm and meritorious service may be acknowledged by National Awards. Recognition and awards act as an incentive to existing donors/ institutions and motivate potential donors to become regular voluntary donors. A very effective motivational tool is an annual prize distribution function which could be held at the local, district or state level. This affords the voluntary organisation an opportunity to publicise its activities in the community and project its positive image. It can outline its goal and spell out the targets it hopes to achieve. Involving a respected person of the community as its Chief Guest, enhances the image of such programme. Efforts should be made to I give maximum possible publicity through mass media. [123] Another method is to organise an "At Home" for repeat donors/group motivators at Raj Bhawan, if possible, or at, any important place involving a V. l. P This makes donors feel appreciated and important. Again, at Republic or Independence Day Functions, outstanding donors/motivators could be honoured by requesting the local authority organising the function to do so. Public recognition makes their commitment even stronger and donors become a part of the movement. Membership of imaginary 5 litre or 10 litre clubs with a presentation of appropriate memento is another way of donor recognition. Printing of photographs of donors in house magazine may boost up morale of the donors and help in recruitment of new donors in subsequent blood collection drive. It will be interesting to have a look at the method of donor recognition in different countries. Awards given in some countries: Germany; • A bronze badge for 3 blood donations • A silver badge for 6 blood donations. • A gold badge for 10 or more blood donations. Austria; • A badge in the form of a drop of blood at the first donation. • A silver badge for 5 donations. • A gold badge for 10 donations. Belgium: • A special certificate for those who have distinguished themselves as blood donors or as voluntary blood donor recruiter. • A certificate at the first donation (giving them the right to an equal amount of blood and plasma for themselves or their next relations for one year). • Certificate after 10 donations. • Small bronze "Pelican" plaque after 25 donations: • Certificate with bronze medal for 40 donations. • Gold medal for 80 donations. U. S. A.: • After first donation a badge in the form of a drop of blood. • For all following donations the same badge in gold with a figure marked corresponding to the number of donations. [124] Greece: • Ordinary badge for upto three donations. • For 5 to 9 donations, a badge with one star, • For 10 to 14 donations, the same with two stars. • For 15 to 19 donations, the same with three stars. • Silver medal and certificate for 20 to 21 donations. • Gold medal and certificate for 50 donations. Turkey: ■ Amongst other genera! recognitions, the Turkish Red Crescent gives women donors a pair of earrings in the form of a drop of blood. In India, recognition of a donor with a badge and a certificate at the time of each donation are very common in most of the states. Special award after multiple donations like ten/twentyfive/fifty donations are also in vogue in some states. In states like Gujarat and Jharkhand donors donating blood for hundred times are specially honoured and they are called "Centurion Blood Donor". 50 TIMES VOLUNTARY BLOOD DONORS UPTO MARCH 2002 2 Donors were honoured upto March 2001 3. Sri Arunabha Chattopadhyay 25 TIMES VOLUNTARY BLOOD DONORS UPTO MARCH 2002 95 Donors were honoured upto March 2001 96. Sri Amitava Cangvili, KolkaLi - 11 97 Sri Alish Chakraboriy, Kolkata - 26 98. Sri Chiranjib Bhattacharya, Howrah 99 Sri Dipak Roy, Kolkata - 48 100. Sri Gobindalal Ghosh, Kolkata- 15 101SnKallolKumarchattaprj ee, Kolkata-30 102Sri Kamalesh Dey, North 24 Pgs. 103. Sri Nanda Dulai Paul, Kolkata - 48 104. Sri Netal Bardhan. Howrah 105. Sri Rajkumar Tat, Howrah I06- Sri Shyamal Kumar Nath, Kolkata-58 107. Sri Subrata Das, Bardhaman 108. Sri Subrata Kumar Panja, Kolkata 13 109 Sri Sukumar Gupta, holkala-^ [125] Donor Retention o establish a transfusion service, dependent totally on voluntary blood Tdonors to meet the entire blood need of the country or the region, a good donor base is absolutely necessary. Building up a good donor base is not an easy task and retaining the donor base is equally difficult. To maintain a donor base, recruitment of new donors and retention of the old donors are absolutely essential. There are people who do not donate blood after their first donation and remain one time donor for the rest of their lives. Retention of old donors is equally important along with the recruitment of new donors. The reason is simple. These pool of eligible donors have already overcome superstitions, taboos and fear complex for donating blood and therefore, the dropping out of such donors weakens donor base. The entire work of donor motivators or organisers is lost if a donor donates blood once and then does not return for future donation. Further, if the reasons for the dropping out of donors are not taken care of, they may in the long run adversely affect the donor recruitment drives. Any whispering from such dropouts communicated to the non-donors is magnified and exaggerated and may strengthen the will of non-donors to remain non-donors for ever. The reasons for dropping out generally are: • Illness/weakness/general health consideration • Lack of time • Lack of communication/information • Unfavourable location or time of the camp • Unhappy past experience • Bad handling by the blood bank personnel • Negative reactions of the blood donation e. g., dizziness, fainting, painful venipuncture, double puncture etc. • Non-availability of blood in time of his/her need ■ Wastage/improper utilisation of blood. Donor retention is emphasised in the days of fatal blood communicable diseases not only because it significantly eases the work of donor recruiters but even more important is the fact that regular repeat donors are safer than new donors. Their blood was tested and transfused safely keeping all records with the transfusion service or the blood bank. [126] An active programme of donor retention is necessary. The most important is the care and handling of donors. Good public relations is the tool. Phlebotomy staff must ensure that the donation process is a pleasant experience for the donor. Scientific donor selection, proper examination and testing instil confidence in the mind of donors. Personal attention, smiling face, clean blood collection site, cheerful refreshment corner and show of sign that donors are wanted by the service help in donor retention. Pinning of donor badge, properly handing over blood group card with correct bloodgroup written neatly speak about the effectiveness of the service. Careful avoidance of haematomas, bruises or double puncture of veins speaks highly about the competence of the blood collecting team. A single case of post donation fainting acts as a big damper at any camp with consequential loss of the donor on the day and also for the future. Donor of less than three donations may need special encouragement before during or after donation to come back again. The regular donor who may be temporarily deferred for medical reasons should be handled carefully with encouragement to come back when fit to donate. Recognition of donors always plays an important role in retention. Besides, the following activities help in donor retention: • Observing days of importance, days of joys and sorrows by different groups help in accepting blood donation drive as a part of annual activity of the organisation: • Outdoor blood collection drives at the same place on a fixed day every year help in retaining old donors: • Donors may be encouraged to become voluntary donor organisers through training programmes/workshops; • Formation of blood donors' club, society, pledge 25 groups. association, friends of blood bank society or group and guiding them with due recognition of their service also help in retaining old donors. The best motivational efforts may go in vain if blood collection teams treat donors indifferently. On the other hand, they can convert one time donors to regular repeat donors. In India if has been observed that: Retention of old donors becomes easier if the task of donor motivation and recruitment are in the hands of one or more weII-organised voluntary organisations rather than on the transfusion service itself. [127] Such organisations may have separate identity but should work hand in hand with the transfusion service in a well co-ordinated manner with mutual respect for each other as an essential member of the team. Donor retention is a global problem. Motivators should keep in mind the following cardinal points to retain donors: How do you keep Blood Donors as Regular Donors? The short answer would be "to make the donors feel wanted and appreciated". To achieve this, the transfusion service or the organisations responsible for donor motivation should do several things. Maintain accurate records: Encourage donors to intimate change of address. Treat donors courteously. Each contact between the staff member of the blood bank or volunteers of social welfare organisations in the field of donor motivation and the donor, whether by letter, telephone, in blood bank, at the camp or at the enquiry/blood distribution centre of the blood bank can either cement or strain the donor-blood bank relationship. Try not to keep donor waiting: Donors are busy people, and may have constraints on their time. Make sure that there are sufficient staff and volunteers available all the time to minimise the pre-donation waiting period. Listen to complaints: Every complaint, real or imaginary, merits investigation and prompt and polite response. A soft (prompt) answer 'take away wrath'. Recognise the donor: Thanks offered at each visit, together with tokens of honour (badges, certificates, and cards) will encourage donors and make them feel appreciated. Inform the donor: Keep the donors aware of the invaluable role they play and the use which is made of their gift of love. Donors are to be intimated and invited to camps when they are eligible to donate again. [128] Encourage donors to bring others: A satisfied and committed donor is the best ambassador of recruiting other donors. No blood bank, however well supported by its donors, can afford to become complacent about such support. The donors' support cannot be taken for granted for ever. The transfusion service must be attentive to its donors, encourage them and inform them of the vital and unique support they are extending in supporting the health services of their community. Individual intimation retains donors [129] Panel Donors There are people and organisations who preach that there is no r =ed of regular blood donation drives or camps. People are to be blood* grouped and listed with addresses and telephone numbers. In time of need they should be called to donate blood. The propagators of this technique Torget the basic point that the blood donors may also be busy people md may not be available always at their recorded addresses. They may be i: or out of station. On top of this, there may be problem of communication, transport and road condition. Above all, who would meet all these costs? This system has not met the basic need of blood banks. Furthermore, when blood is needed, time may be the most important factor. Some organisations have printed donors' directory. They have burnt their fingers. Donors being approached from different corners, on the same day, have decided not to donate blood again. It may be appreciated that donors would love to donate blood according to their convenience and at a convenient camp. They would like to donate blood with known faces around, They would not like to donate amidst stony silence in isolation in a blood bank. Besides, there is the ethics of anonymity between the donor and the recipient. Thus the method of 'on call donation system' ultimately leads to directed donation resulting in many social and legal problems. It has been observed that unless one has never donated blood in camps, when empaneled as a panel donor on the basis of blood grouping, one does not respond in time of need as an 'on call donor'. In some European countries they are called "Paper Donors". Still, there is a need for panel donors for a second line of support for rare group, fresh blood and preparation of particular component. Such panel can only be developed from amongst the regular donors after obtaining their consent in writing. The panel has to be maintained by the blood bank or a reputable, voluntary blood donor organisation in the field. Such a panel should never be made public. The blood bank or the voluntary organisation should act as an intermediary between the donors and the patients in emergencies requiring blood; otherwise confidentiality between the donor and the recipient cannot be maintained. [1301 The record of such panel donors should be maintained, updated for the simple reasons that they should never be approached for donation more than once in three months and also for facilitating award for multiple donation. They should be asked to donate once or twice in a year in any camp and save the other two for on call donation to maintain their habit of blood donation. A meet of such donors once in a year with blood bank or voluntary organisation in a ceremonial manner for sharing of experience and better utilisation of the panel would be helpful. In the meet various aspects of transfusion service should be discussed and good suggestions from the panel donors, if implemented, may help in maintaining the panel effectively. The modalities of record keeping of such donors and method of approaching and utilising them sensibly may vary from place to place but should be pragmatic and easy to understand, keeping in mind all the time that donors' convenience and goodwill are most important for such service. It should be kept in mind by donors, blood banks and blood users that this panel is not a substitute for regular camp donation but a supplementary support to camp donation. In cases of regular blood requirement of genetic disorder like Thalassaemia or Haemophilia, a regular blood donation camp can be organised in the locality of the patient or the workplace of their parents. From these camp donations, a list of twenty five donors belonging to right group of the patient may be prepared with consent. Such donors may be requested to adopt the child with the genetic disease in respect of their blood need. This list may be made available to the parents of the child who may contact the donors when blood would not be available from the blood bank owing to shortage. Such donors should be advised to donate at least once or twice in a year in a camp and save remaining two for possible donation for the child as on call donor. Such donors would not normally be asked to donate for the child more than once in two years. A get-together of such donors, patients and their parents once in a while would be enjoyable, refreshing and useful. Such donors may form a very informal 'Donors' Club' for the child. The presence of many such groups or clubs in the society would be some sort of insurance of the children with hereditary blood disorders in respect of their blood need. By this method confidentiality between the donor and the recipient cannot be maintained. But as a very special case the method may be accepted in the interest of the child. [131] Law and Transfusion Service Blood and blood components are categorised as a "drug" under Section 3(b) of Drugs and Cosmetics Act, 1940 because of their interna adminstarion. This Act and the Rules thereof provide the legal framework for regulating the functions of blood banks, which in turn directly irnpart and determine the quality of the blood transfusion service delivery in thecountry. Since initial formalities, the ambit of the Drugs and Cosmetics Ac 1940, has been expanded and the Rules have frequently been amended to incorporate blood as drugs because of their internal administration and use in treating diseases. The transfusion of blood cells is also transplantation and cells must survive and function after transfusion in order to have therapeutic effect. As with drugs, adverse effects may occur due to blood transfusion. All these necessitates careful consideration and handling of service in accordance with the law of the land. Article 21 under part III titled fundamental rights of the Constitution of India clearly spells out that no person shall be deprived of his life. Blood transfusion can be life saving and also can be fatal, therefore, comes under this section of fundamental rights. Besides under chapter XIV of the Indian Penal Code Section 269 provisions for fine and imprisonment for negligent act likely to spread infectious disease dangerous to life and section 270 of the Malignant Act likely to spread infection of disease dangerous to life covers blood transfusion and blood banking in all aspects. Consumer Protection Act Consumer Protection Act of 1986 came into force in July, 1987 for all goods and services, covers all sectors - private, public, cooperative etc It enshrines the six rights of the consumers: • Right to safety • Right to be informed • Right to choose • Right to be heard • Right to seek redressal • Right to consumer education. The portions of the Act are compensatory in nature. Supreme Court Directive The Supreme Court on November 13, 1995 upheld the National Consumer Commission's judgement of April 1992, whereby patients who [132] received deficient services from medical professions and hospitals are entitled to claim damages under this Act. Naturally, blood banking service comes under this Act and both donor and recipient may take the cover of this Act. public Interest Litigation On a public interest litigation filed by a Delhi based organisation 'Common Cause' by a writ petition (civil) no 91 of 1992 under Article 32 of the Constitution of India, Hon'ble Justice S C Agarwal and Hon'ble Justice G B Pattanaik on January 4, 1996 issued the following directives: 1. The Union Government shall take steps to establish forthwith a National Council of Blood Transfusion as a society registered under the Societies Registration Act. It would be a representative body having in it representation from the Directorate General of Health Services of the Government of India, the Drug Controller of India, Ministry of Finance in the Government of India, Indian Red Cross Society, private blood banks including the Indian Association of the Blood Banks, major medical and health institutions of the country and non-Government organisation active in the field of securing voluntary blood donations. In order to ensure coordination with the activities of the National Aids Control Organisation, the Additional Secretary in the Ministry of Health, who is in charge of the operations of the programme of National Aids Control Organisation for strengthening the blood banking system could be the President of the National Council. 2. The National Council shall have a secretariat at Delhi under the charge of a Director. 3. The basic requirements of the funds for the functioning of the National Council shall be provided by the Government of India but the National Council shall be empowered to raise funds from various other sources including contributions from trade, industry and individuals. 4. In consultation with the National Council, the State Governments/ Union Territory Administration shall establish a State Council in each State/ Union Territory which shall be registered as society under the Societies Registration Act, The State Council should be a representative body having in it representation from Directorate of Health Services in the State, State Drug Controller, Department of Finance of the State Government/Union Territory Administration, important medical institutions in the State/Union Territory, Indian Red Cross Society, private blood banks, Non-Government Organisation active in the field of securing voluntary blood donations. The Secretary to the Government in charge of Department of Health could be the President of the State Council. [133] 5. The State Council should have its headquarters at the premises of the premier medical institution or hospital in the State/Union Territory and should function under the charge of a Director. 6. The funds for the State Council shall be provided by the Union of India as well as the State Government/Union Territory Administration. The State Council shall also be empowered to collect funds in shape of contributions from trade, industry and individuals. 7. The programmes and activities of the National Council and the State Council shall cover the entire range of services related to operation and requirements of blood banks including the launching of effective motivation campaigns through utilisation of all media for stimulating voluntary blood donations, launching programmes of blood donation in educational institutions, among the labour, industry and trade, establishments and organisations of various services including civic bodies training of personnel in relation to all operations of blood collection, storage and utilising, separation of blood groups, proper labelling, proper storage and transport, quality control and archiving system, cross-matching of blood between donors and recipients, separation and storage of components of blood, and all the basic essential of the operations of blood banking. 8. The National Council shall undertake training programmes for training of technical personnel in various fields connected with the operation of blood banks. 9. The National Council shall establish an institution for conducting research in collection, processing, storage, distribution and transfusion of whole human blood and human blood components, manufacture of blood products and other allied fields. 10. The National Council shall take steps for starting special postgraduate courses in blood collection, processing, storage and transfusion and allied fields in various colleges and institutions in the country. 11. In order to facilitate the collection of funds for the National Council and the State Councils, the Government of India (Ministry of Health and Ministry of Finance] should find out ways and means to secure grant o100% exemption from income tax to the donor in respect of donation made to the National Council and State Councils. 12. The Union Government and the Government of the States and Union Territories should ensure that within a period not more than one year all blood banks operating in the country are duly licensed and if a blood bank is found ill equipped for being licensed, and remains unlicensed after [134] the expiry of the period of one year, its operations should be rendered impossible through suitable legal action. 13. The Union Government and the Governments of the States and Union Territories shall take steps to discourage the prevalent system of professional donors so that the system of professional donors is completely eliminated within a period of not more than two years. 14. The existing machinery for the enforcement of the provisions of the Act and the Rules should be strengthened and suitable action be taken in that regard on the basis of the scheme submitted by the Drugs Controller (I) to the Union Government for upgradation of the Drugs Control Organisation in the Centre and the States (Annexure II to the affidavit of Shri R Narayanaswami. Assistant Drug Controller, dated September 16,. 1994. ) 15. Necessary steps be taken to ensure that Drug inspectors duly gained in blood banking operations are posted in adequate numbers so as to ensure periodical checking of the operations of the blood banks throughout the country. 16. The Union Government should consider the advisability of enacting a separate legislation for regulating the collection, processing, storage, distribution and transportation of blood and the operation of blood banks in the country. 17. The Director General of Health Services in the Government of India, Ministry of Health shall submit a report by July 15, 1996 about the action taken in pursuance of these directions. 18. It will be open to the Director General of Health Services, Government of India as well as the National Council to seek clarification/ modification of these directions or further directions in this matter. Drugs and Cosmetics Act In accordance with the directive of the Supreme Court, NACO appointed an expert committee to revise the Drugs and Cosmetics Rules Pertaining to blood banking. After a series of meetings spanning over two years the amended Drugs and Cosmetics Rules virtually a total revision came into force with effect from April 5. 1999. The rules thereafter were modified thrice till 2003. Under this act and its rules, no blood bank in the country can function without first obtaining license from the Central License Approving Authority of the Ministry of Health and Family Welfare on the basis of recommendation [135] of Director, Drug Control of the state by abiding the condition laid down: in, the Act and the Rules. The license has to be renewed on expiry. The most important point of this legal provision motivators should take note of that blood from voluntary out door camps can only be collected by: * A licensed Government Blood Bank, * Indian Red Cross Society, ' A licensed Regional Transfusion Centre State Blood Transfusion Council constituted Government. that the donor blood donor in designated by by the State Relevant extracts of the Drugs & Cosmetics Rules (1999) for blood donor motivators are given in Annexure IV. Drugs and Cosmetics -:: ^: - • Act 1940. - -:; -. (23 Of 1940) : -, THE DRUGS AND COSMETICS RULES, 1945 amended by THE DRUGS AND COSMETICS (THIRD AMENDMENT}. RULES, 2003 t - [136] Ethics in Transfusion Service The word 'Ethics' is derived from the Greek adjective 'Ethica' which comes from the Greek substantive 'ethos' meaning customs, usages and habits. It is also known as 'Moral Philosophy'. The word moral is derived from the Latin substantive 'mores' which also means customs or habits. Customs are not merely habitual ways of acting. They are ways approved by the group or society. Thus 'Ethics' is the science of rightness and wrongness of conduct. Conduct is purposive action, which involves choice and will. It is the expression of character which is a settled habit of will. Character is the permanent habitual inner bent of mind, and naturally reflected in habitual conduct. This is how any text book of 'Ethics' will explain the term; a term intimately connected with the 'science of ideal involved in human life'. Blood transfusion is a complex science that links healthy blood donor with the ailing patient in quest of a new lease of life with various intermediaries and a system. The first requirement is the blood donor. Only four out of a thousand people in India can think of donating blood. Dearth of donors prompted many people to trade in human misery, to open commercial blood banks engaged in buying and selling of blood. Nowhere in the world can paid professional sellers ensure the quality of blood in spite of sophisticated post donation tests. So, all over the world stress is given on voluntary blood donors and switching over to total voluntary blood programme. To achieve this, the culture of blood donation should be the custom of the community. This can be done by converting the Egoism of individuals to Altruism. The ideal life of one requires others to complement it, and it is by mutual help that the whole develops towards perfection. An individual is a member of a social unit, his supreme will should not simply be the perfecting of his own life, or the realisation of what appeals to him as the most fundamental values but also the perfecting of the society to which he belongs. To a great extent one end will coincide with the other. When we seek simply our own individual ends, this attitude is called 'egoism' while the term 'altruism' has been used to devotion to the ends of others. We can realise the true self or the complete good only by social end. In order to do this, we must negate the merely individual self, which is not the true self. We must realise ourselves by becoming worthy of the society to be useful for others. The more fully we do so realise ourselves, the more do we reach an universal point of view - i. e., a point of view from which our own private good is no more to us than the good of anyone else. This [137] is self-realisation — self realisation for the sake of the whole. This good is clearly a social good. With conviction and faith in this philosophy, any individual, group and organisation can take up the task of blood donor motivation, recruitment and retention by converting 'egoism' of individuals to altruism, remembering all the time that motive means what moves us or causes us to act in a particular way. The means should not be overlooked. Education of soul is the only tool. The donor should be assured of absolute confidentiality about identity and blood test results and reasons of deferral. Then comes the blood bank to collect blood to ensure safety of the donor and safety of the recipient. Scientific donor screening, maintaining confidentiality at every stage should be the creed of blood bank personnel to collect blood and maintain adequate stock. In storing and distribution of blood the administrative or personal balance of convenience should not get precedence but the need of the patient should be the supreme. For this, development of personnel at all levels through training, education and self-development would be necessary. The community should have appreciation for the blood donor, blood bank personnel including those behind the public eyes working faithfully in the laboratory, counter and other places. Then comes the doctors, the users of blood. Blood transfusion is transplanting from outside in large quantity to human circulation system. There are some hazards which may be fatal too. Unnecessary transfusion should be avoided to ensure safety of the recipient. In case of planned, cold or chronic cases, the attending doctor can deter a patient's relatives from going' to commercial blood sellers. He/she can inspire the patient's friends and relatives to donate blood for some one whom they love. He/ she can help the blood bank by sending the report of blood transfusion through feed back/reaction forms. One more thing. Asking for the so-called fresh blood every now and then puts the patient in the hands of paid donors in disguise and also to the hazard of untested blood transfusion. This ethics can be implanted among the doctors from their student days through education and demonstration and culture of the elders. International Society of Blood Transfusion, International Federation of Red Cross and Red Crescent Societies, World Health Organisation between the period 1948 and 2000 have released various documents on the ethics of blood transfusion service. [138] Finally, it may be said, that the laws of a country are made by the rulers and are therefore changeable. Laws of nature are constant, inviolable, all pervading and unchangeable. The laws of ethics evolve and cannot be changed but they may be violated. On the attitude of the community about the ethical laws/practices depends the quality of life of the people of the country. A Code of Ethics for Blood Donation and Transfusion formulated by International Society of Blood Transfusion on July 12, 2000. The objective of this code is to define the ethical principles and rules to be observed in the field of Transfusion Medicine. 1. Blood donation including haematopoietic tissues for transplantation shall, in all circumstances, be voluntary and non-remunerated; no coercion should be brought to bear upon the donor. The donor should provide informed consent to the donation of blood or blood components and to the subsequent (legitimate) use of the blood by the transfusion service. 2. Patients should be informed of the known risks and benefits of blood transfusion and/or alternative therapies and have the right to accept or refuse the procedure. Any valid advance directive should be respected. 3. In the event that the patient is unable to give prior informed consent, the basis for treatment by transfusion must be in the best interests of the patient. 4. A profit motive should not be the basis for the establishment and running of a blood service. 5. The donor should be advised of the risks connected with the procedure: the donor's health and safety must be protected. Any procedures relating to the administration to a donor of any substance for increasing the concentration of specific blood components should be in compliance with internationally accepted standards. 6 Anonymity between donor and recipient must be ensured except in special situations and the confidentiality of donor information assured. 7 The donor should understand the risks to others of donating infected blood and his or her ethical responsibility to the recipient. 8 Blood donation must be based on regularly reviewed medical selection criteria and not entail discrimination of any kind, including gender, race, nationality or religion. Neither donor nor potential recipient has the right to require that any such discrimination be practised. [139] 9 Blood must be collected under the overall responsibility of a suitably qualified, registered medical practitioner. 10 All matters related to whole blood donation and haemapheresis should be in compliance with appropriately defined and internationally accepted standards. 11 Donors and recipients should be informed if they have been harmed. 12 Transfusion therapy must be given under the overall responsibiliiy of a registered medical practitioner. 13. Genuine clinical need should be the only basis for transfusion therapy. 14 There should be no financial incentive to prescribe a blood transfusion. 15. Blood is a public resource and access should not be restricted. 16. As far as possible the patient should receive only those particular components (cells, plasma, or plasma derivatives) that are clinically appropriate and afford optimal safety. 17 Wastage should be avoided in order to safeguard the interests of all potential recipients and the donor. 18. Blood transfusion practices established by national or intemational health bodies and other agencies competent and authorised to do so should be in compliance with this code of ethics. Blood safety Instruments * Legislation & regulation * Committee on Ethics * operational strategies * BloodPolicy Ethical principles Medicalprofessionals Human dignity Non discrimination Honest & clear information Free & informed consent Confidentiality Medical secrecy Who is responsible ? *National authorities * Health system RIGHTS DONOR RECIPIENT OBLIGATIONS [140] Public Relations in Transfusion Service It may be interesting to look back to the historical background of public relations. Emperor Ashoka used to inscribe his edicts on pillars and hills I to inform his subjects. There is also ample evidence in records to show that early Roman and Greek emperors took great care and attention to influence public opinion. The American revolution was initiated by a small group of men including Thomas Paine, Benjamin Franklin. Hamilton and Thomas Jefferson — all of whom utilised public relations to influence public opinion in favour of the struggle for independence. In England too, pamphleteers of the eighteenth century like Jonathan Swift and Daniel Defoe were using methods to propagate their ideas which resembled the present day PR practice. The phrase "Public Relations" was first coined by PresidentThomas Jefferson when he scratched out the words "State of thought" and replaced hose with the word "Public Relations" as early as 1807 when he was writing his address for the seventh Congress. Modern profession of Public Relations can however be traced back to 1923. Dr Edward L Bernays wrote a book "Crystalising Public Opinion" a full length treatise on Public Relations. At every stage of transfusion service Public Relations is the tools and implements based on both oral and written communication to ensure safe blood transfusion. But mere publicity is not public relations. Publicity is mostly nonI personal stimulation of demand for a product or business unit by planting commercially significant news about it in published media or obtaining favourable presentation of it through print or electronic media. Public Relations practice is the planned and sustained effort to establish and maintain goodwill and understanding between an organisation and its publics. Publics is a part of jargon of public relations. It is an invented word not to be found in any orthodox dictionary. It shows that public relations is rarely concerned with the "General Public'. [141] An ideal blood bank has five basic functions, as stated and explained earlier: • Blood donor recruitment • Blood collection • Blood processing and storage • Blood distribution • Post transfusion follow-up and research. Therefore, basic Publics of blood banks would be: • Blood donor motivators and donor organisations • Blood donors and intending blood donors • Community • Blood bank personnel • Patients' relatives in quest of blood • Blood users • Media personnel. Advertisement is not public relations. The difference between advertisement and public relations is: Advertising Media Public Relations Media Display of. Classified Advertisements Feature Articles, News Stories Outdoor advertisement Posters Educational Visual Aids and Posters Sales Promotion Schem Educational Literature Sates Sales literature Seminars. Meetings Modern marketing is also not public relations. Marketing deals with market and public relations deals with publics. Public relations is actually a transfer process. In blood banking a negative situation is converted into positive achievement through knowledge — the result is the objective of public relations, understanding in blood banking and the process is known as Public Relations. In tabular form Public Relations in blood banking may be summed : up as an activity to change the behavioural pattern from a Negative Situation | to Positive Achievement as: [142] Negative Situation Non Donor/Irraiional User Positive Achievement Blood Donor/Rational User Sympathy Acceptance Interest, Knowledge Hostility Prejudice Apathy Ignorance The Public Relations is a transfer process. Public Relations is NOT • A barrier between the truth and the public. • Propaganda to impose a point of view regardless of truth, ethics and public good. • Publicity aimed directly at achieving sales although public relations activities can be very helpful to sales and marketing efforts. • Composed of stunts or gimmicks. • Unpaid advertisement. Therefore Public Relations practice includes: • Everything that is calculated to improve mutual understanding between an organisation and ail with whom it comes into contact, both within and outside the organisation. • Action to discover and eliminate source of misunderstanding. • Action to broaden the sphere of influence of an organisation by appropriate publicity, advertisement, exhibitions, films, etc. • Everything directed towards improving communication between people and organisations. International Public Relations Association (IPRA) defines Public Relations as: "Public Relations practice is an art and science of analysing the trends, predicting their consequences, counselling organisations, leaders and implanting plans and programmes of action which will serve both the organisation and the public". The national body, Institute of Public Relations (IPR) has adopted more direct definition as: "Public Relations practice is a deliberate, planned and sustained effort to establish and maintain mutual understanding between the organisation and the public. " [143] Seat and Draw Competition for Motivational Posters [144] Communication in Donor Recruitment All living organ isms communicate. Starting from the uni-cellular amoeba to the highly sophisticated human being, all living creatures communicate their feelings in one way or another. In modern era the following are the common modes of communication: • S i g n communication • Oral communication • Written communication • Audio-visual communication. Human beings communicate by any of the above methods. In our Society, because of our complex mental nature, such communication may often be deceptive and difficult to explain. Sign Communication Much of our communication is through signs, - the show of fists, the look of the eyes, the shaking of the head (the North Indian's "no" and the South Indian's "no" are just the opposite here), the clapping of hands (here too, slow clapping means just the opposite of the clapping for applause) or even a silent yawn are some of the many forms of sign communications, which, though not vocal, are often very much understandable. The communicator should remember the significance of all such signs, particularly when he/she addresses the public for getting his/her message through. Oral Communication The spoken word, though short lived, has immense power of influencing. In fact, it can draw hearts near or tear them as under, it can lull a mob or move an army. But the success of the spoken word depends entirely on how effectively the speaker uses it. All leaders, generals and motivators have succeeded on account of their excellence in verbal communication. Such communication has an important advantage of the speaker noting audience reaction all the time he speaks and he can thus modify his address according to the needs of the situation. Basic Communication Theory But, whatever be the method of communication, the theory of [145] communication to be effective, is always the same and can be represented in the simple diagram as shown below: Channels Communicator encodes message Media Newspaper, Television, Cinema, Poetry. Etc. message decoded Target audience Response Feed-back It will be seen that the communicator encodes a message and sends t through different media at his command to reach the target audience. The message is decoded by the target audience which generates a response, which, again serves as a feedback to the communicator for revised action as necessary. The important factors in this programme obviously are not only the design of the message but also the study of the feedback. If the message s not decoded in the manner the communicator desires it to be, the response will be different from the intended one and the communicator will have to redesign or revise his message. This is of particular importance to any speaker whose action must be instantaneous to the response. Communication Effectiveness: The Design and Delivery of Message Wilbur Schramm has laid down some excellent points to make communication effective. He states: • The message must be designed and delivered in a manner so that it attracts the attention of the target listener. • It must employ signs which refer to experiences common to the target listener and match his value system. • The message must arouse a sense of needs in the listener and suggest ways to satisfy them. • It must reach at a time after the listener may be moved to make the desired response and be allowed to do so. Lord Mahabir, bom in 599 BC, in his sermon preached that carefulness in speech (Bhashasamiti) consists in avoiding slanderous, ridiculous, harsh, critical, boastful and meaningless talk. These bring good neither to oneself nor to others. He emphatically preached that a wise ascetic should speak [146] what he has seen; his speech should be brief, free from ambiguity and clearly expressed. His speech should neither be deceptive nor cause anxiety to any one. The postulates of Schramm, however simple they may seem, should be remembered at all times by motivating speaker. They speak about the manner and the theme of the message have to be designed, employing experience and analogies that are common to the listening public and also about the time to be chosen for delivering it so as to make an effective impact. The occasion, the time, the facilities, the mood and the inclination of the listeners must be keenly observed before and during the process of communication. The message will have to be modified, pruned or enlarged as the situation may demand. The time planning, i. e., duration of speech or talk is the key to success and must be according to the situation. While delivering the message, its contents must not be made too technical or stuffed with statistics. It should contain a promise and must lead to a personal ego-satisfaction of the listener only then he will be motivated- A blood donor or blood recipient in the role of donor motivator will succeed much more in motivating his fellow-workers towards blood donation than a doctor who is much more knowledgable and may even be a better speaker. In verbal communication, the qualities of a speaker are very important. He/she should know his subject well, and should have a good bearing, appropriate dress and proper manners. He should have a loud dear voice with good articulation. He/she should also be able to make friends with the audience, earn trust and be in a position to persuade them. Thus, he/she should be a person with versatile knowledge and taste. Finally, he/she must be tenacious enough to drive his/her point home. The talk he/she delivers should have the following desirable qualities: • Appropriate for the audience • Concise, informative and appealing • Suiting the time and attitude of the listeners • Clear, lucid language• Correctly pronounced without mannerism or unnecessary repetition of words and phrases • Should be delivered by the speaker who should look to each section of audience by rotation and not vaguely or to one section of it only • Contain a sense of humour. Properly chosen moments of lightness, even in a serious topic, make a speaker impressive and make a talk interesting. [147] The 'X'factor And yet. even by possessing all the above qualities perfectly, a speake might fail and without consciously following them, while another may succeed. This is due to what is called the unknown factor or "X" factor. This factor is truth and the speaker's firm conviction about it. If the speaker believes in what he/she says and can say it well, it has a magic influence or the audience. Truth itself has an inherent strength that gives any speech i sound foundation. So, if the speaker is himself/herself truly convinced c his/her mission, words that flow out of him/her are spontaneous. He/she can electrify and touch the hearts of his/her audience and move them it the manner he/she desires. Any campaigner would do well to remember it Donation of blood on a voluntary basis is a social necessity and for a noble cause. If the campaigner sincerely believes in it and can voice his/her conviction well, it should not be difficult for him/her to win his/her audience, even if partially, Conviction to convincing is only one step away. In Indian context oral communication backed by display materials and distribution of take-home printed materials are found to be most effective. In the oral communication for motivation of blood donors the following should be focused: • Need of blood for transfusion • No substitute of human blood • Need and importance of voluntary blood donation to ensure safe blood transfusion • Statistics of deficit in supply of blood • Blood volume, surplus quantity, amount of donation, recuperation period, shelf-life of blood • Eligibility of donors and donor education for self exclusion • Blood donation is a social and moral responsibility. Ten Commandments of Good Oral Communication • Clarify ideas before attempting to communicate. • Examine the purpose of communication. • Understand the physical and human environment while communicating. • In planning communication, consult with others to obtain the1 suggestions as well as the facts. • Consider the content and the overtone of the message. • Whenever possible, communicate something that helps or is valued by the receiver. [148] • • • • Communication to be effective requires follow-up. Communicate messages that is short-run and longrun importance. Actions must be congruent with communication. Be a good listener. Written Communication Though effective, the limitation of the written form of communication is that it can influence literate persons only. Poets, authors and editors have used the written word to make communication charming and even memorable. Even today, speeches before august gatherings are read out from written material. It has the unique advantage of being precise, concise and unambiguous. It. however, has one shortcoming that the communicator cannot project his personality and give the finer touches of emphasis which he/she can do with the spoken word. Ten commandments of Good Written Communication • • • • • • • • • • Use simple and familiar words. Use personal pronouns (such as you) wherever appropriate. Give illustration and examples; use charts. Use short sentences and paragraphs. Use active verbs such as "The organisation plans". Economy on adjectives. Express thoughts logically and in a direct way. Avoid unnecessary words. Use simple words and phrases. Avoid printing or typographical errors. The audio-visual communication A combination of speech and sight, this form of communication is perhaps the best because it incorporates the best features of the written word, the painted picture and the spoken word. Appealing to the senses of sight and hearing, its imprint on the mind is most. It can also motivate an illiterate audience. Stories as Vehicle of Communication Since the prehistoric days stories have been used for passing around the message. Stories of the Upanishads. Parables, stories of Vishnu Sharma and Panchatantra are well known. In donor motivation and recruitment, stories are being used with great success. Reasons for success are; • Stories built on the impact of spoken words are morepowerful than written words. [149] • Everyone is interested in stories; they can identify themselves with characters of the stories. • While some educated people might have been trained to thin: in a logical, organised way, the story format is closer to the wa*. most people think, including the educated community. • People remember information better when it is presented in, story format than in a mere formal talk or lecture. • Stories can make truth concrete or absolute - abstract ideas can be expressed in everyday terms. • Stories begin with things people understand most. • Stories can help people to discover action plan/values/principles for themselves or develop an attitude towards life. The human values might constitute main ingredients of the story with the hints of blood donation on the sidelines. Another approach is to have the main story dealing with topics having a high universal appeal with characters real or imaginary and donation of blood as derived sub-theme. A well developed story will provoke a response if listeners find it to be relevant to their life. The stories should be presented in an interesting way. by changing one's voice to suit the different sequences and the characters. If people believe in the stories and identify themselves with the characters they are more likely to remember the message and take action to change their behaviour. To find stories, one must look around and pick up stories from every day life. The Epics and literatures are the store house of enough stories. A caution of story telling is that one should not miss wood for the trees. Too many stories without appropriate linkage with the theme may spoil the presentation. Using Visual Aids in Donor Motivation Sessions Visual aids such as films, slides, transparencies can help to clarify the talk and highlight salient points but these may be counter productive to the talk in the Indian context. Darkness in the room may result in one's losing eye contact with the listeners, so essential for successful communication In the middle of the talk, the hardware may go out of order or sudden power failure may lead to confusion. Visual aids are not vital tools in donor motivation sessions. Those can be used if they add real value to the talk. The speaker should make sure whether or not they are really needed, and if so. which type should be used - OHP, slide projector or video and should get the answers to the following [150] questions before using the visual aids: • Does the visual aid add clarity to the speech? • Is the meaning of the visual aid instantly obvious ? • Can the speaker talk just as effectively without it ? Transparecies Here are tips for successful use of transparencies in such places. They are; • • • • • • • • • • • • • • • Have no more than five words in a line and not more than seven lines in a transparency; too many transparencies may spoil the talk. Omit all unnecessary details. Letters and words should be big enough to, be clearly visible even from the back of the room. Avoid spelling mistakes. Don't spend more than a minute or two discussing each heading. Consider making transparencies with drawings, cartoons with the help of computers and colours. Consider covering up the headings revealing only one at a time to prevent the audience from getting ahead of the speaker. Transparencies should be numbered and should be in order. Projector light should be switched off whenever there are pauses between transparencies. Never compel the audience to look at a brightly lit but empty screen. Talk to the audience and not to the transparency. Practice using OHP before the audience enters the room. Make sure written materials fit in the screen. Practice transferring from one transparency to another smoothly. Make sure that the there is a table at the side of OHP high enough to lay transparency before and after use. Do not be in the way of anyone viewing the screen. Transparencies are not substitute for speakers' home work or organisation of presentation. These can only be visual supplements to the talk. Only imaginative preparation and use of transparencies can help in presentation as aids. Slides The use of slides to display the presentation material can be an effective technique, if and only if the audience needs to see it. A 35 mm slide programme creates a highly professional image. Similarly, if the slides are well chosen, less text is needed. Disadvantage of using slides is in [151] momentary lo40ss of eye contact with the audience due to darkness. Slides are to be kept in plastic pages, in a cool dry area. This will keep them from warping. The slides on the very top (as they appear in a box) starting from front left and moving towards back right are to be maintained. This way when loading the projector, a quick glance will ensure that all the slides ere in the right side up and in order. Flip charts A flip chart is the easiest visual aid to create. It can be done in advance or as the audience responds. While using a flip chart for presentation, the presenter should remember not to speak to audience with his back facing them. Care must also be taken regarding spelling, legibility, etc. Though flip charts are the easiest of all visual aids to make, they are relatively time consuming. Printed flip charts for one campaign may be used by a number of people. Presentation with Computer Presentation with computer (with LCD), however attractive it may appear, would not be suitable in motivation session for most of the target group owing to logistics and cost. Preparation of material for such presentation needs expertise and presentation requires practice. Using Visual Aids While using visual aids, there are a few points to be kept in mind. Consistency: It is important that art work and lettering be consistent from slide to slide or transparency to transparency. All the titles should utilise the same size print. Centering: The centre of the visual aid is the first place the audience will focus their attention on. This is followed by the top of the visual aic. Visual aids ought to be arranged in such a way so that the most important message is in the centre, and other important messages are in the top areo. Colour psychology: Different colours get different reactions from the audience. While white stands for peace and tranquility, blue stands for cool and relaxation. Purple stands for royalty and richness. Red stands for alarm and stimulation. Yellow stands for happiness and warmth. Green stands for health and freshness. Too many colours should not be used in one transparency. [152] Over doing: Too many visual aids can be distracting. Placement: Placement of visual aid should be such that the presenter and the aid receive equal attention. Designing Visual Aids All visuals should be properly planned for the target audience. Simplicity: Each visual should have one main point and a maximum of 3 or 4 minor points — more the number, less is the effectiveness. Format: The format should be the same for all visual aids of a particular presentation. Not cue cards: Visuals should not be a cue card. One should know his/her presentation well enough so that the presenter need not have to rely on visuals to know what comes next. Distribution of Take Home Materials It is always better to distribute take-home materials at the end of presentation. Listening Listening is an important tool in donor recruitment in individual approach or group approach strategies. The chief complaint about donor recruiters is that they do not really listen. They always go on talking. This is a mistake. Listening is a part of communication. One can pay people no greater honour than to actually absorb the content and intent of what they have to say. Communication in donor motivation session is neither one way nor superficial stringing of words together. Communication for blood donor recruitment is actually a communication between heart and heart supported by head. Once people find that motivators are willing to take the time to understand them, they will take time to arrange thoughts into concepts that are easier to comprehend. The motivator may even create some listeners of his/her own. Then one can reach a state where true communication takes place. The motivator is actually transmitting and receiving real messages. Once the motivator has a basis for eliminating or preventing misunderstandings, success is at hand. Nothing is more important than true understanding and nothing is harder to come by. [153] President Lincoin makes "A few appropriate remarks" At the dedication of the National Cemetery at Gettysburg. On November 19, 1863 "Fourscore and seven years ago, our fathers brought forth upon this continent a new ation, conceived in liberty, and dedicated o the proposition that all men are created equal. Now we are engaged in a great civil war, testing whether that nation, or any nation so conceived and so dedicated, can long dure. We are met on a great battlefield of that war. We are met to dedicate a portion of it as final resting place of those who here gave their lives that that the nation might live. It is altogether fitting and proper that we should do this. But in a larger sense we cannot dedicate - we cannot consecrate - we cannot hallow this ground. The brave men, living and dead, who struggled here, have consecrated it far above our poor power to add or detract. The world will little note, nor long remember, what we say here, but it can never forget what they did here. Is for us, the living, rather to be dedicated here to the unfinished work that they have thus far so nobly advanced. It is rather for us to be here dedicated to the great task remaining before us, that from these honored dead we take increased devotion to that cause for which they here gave the last full measure of devotion; that we here highly resolve that these dead shall not have died in vein; that this nation, under God, shall have a new birth of freedom, and that government of the people, by the people, for the people, shall not perish from the earth". The president had spoken in a clear, loud voice, but he was through before the audience felt he was fairly started, and the applause was Slow and perfunctory. Some newspaper actually ridiculed the address, a few praised it; a few people at once recognised a masterpiece- Edward Evertte, the orator of the day who spoke for two hours, himself wrote to the President the next day: "I should be glad if I could flatter myself that I came as near the central idea of the occasion in two hours as you did in two minutes". In his grateful reply Lincoln said: "In our respective parts yesterday, you could not have been excused to make short address, nor I a long one. I am pleased to know that, in your judgement, the little I did say was not entirely a failure". [154] Blood- Share Life [155] IEC Materials for Donor Recruitment A lthough oral communication, both for short term and long ter n strategies to recruit voluntary blood donors in the Indian context has been found to be useful and has been strongly recommended, supporting information, education and communication materials in print would be needed as complementary tools and implements. Most important IEC material is poster. The message of posters should be short, simple and easy to understand. Message may be emotion; 1, statistical or scientific. The visuals should be easy to understand and must appeal to the value system of people of the land or region. The language should be always local. The trained motivators would be able to write the copy of such posters and an artist having knowledge or experience in blood donation may be able to design visuals. Type of printing would depend on the quantity required and fund available. Printing may be lithography, letterpress, silk screen, offset or even xerox offset. The quality of paper may be selected depending on the design and purpose of the poster. The paper may be art paper, chromo art paper, maplitho, white printing, bond or even news print. Posters for permanent display or for using over and over again may be laminated and or mounted on board or wood. A number of posters covering all aspects of blood and blood donation may constitute a set and may be used for blood collection drive. For outdoor camps, Books, booklets, folders, stickers, sunshades, calendars, paperweights, paper handfans, key rings and badges with appropriate message and design or content can be supportive lEC materials for blood donor recruitment. Postal stamps of many countries on blood donation give ideas of visuals which may be adopted for lEC material. AVIS, Italy has coloured pictorial booklet with all stamps on blood donation so far published by different countries. Slides, transparencies, film, filmstrips. video and audio cassettes, can be used as IEC materials. In motivation sessions in India it would be difficult to organise hardware and curtains. Furthermore, by making the room dark the motivator may lose eye contact with the audience. Eye contact with audience is an essential ingredient of successful direct oral communication. But motivators should learn the technology to produce such materials with the help of others and they should be able to use those when the situation so demands. The motivators should be careful while designing messages for IEC materials. The message must be clear and if possible indicate some benefit to the donor or to the society. The message must be tested with donors and non-donors. The messages developed and tested should be used as frequently as possible because repetition is a key element in communication process. In addition to creating the messages, graphic elements to accompany the messages sometimes may be useful. lEC Materials Used in Different States of India 1, Poster 7. Paper Article with Message • Class time-table • Emotional • Message • Sun guard • Statistics • Fan • Science 8. Visual • Announcement • Slides 2, Flip chart • Transparencies • Science 9. Cards • History • Greetings • Statistics • Announcement • Story 10. Books & Periodical 3, Sticker • Book • Message • Folder • Announcement • Pamphlet • Watch Sticker • News Letter 4, Badge • Journal • Message • Bulletin • Symbol 11. Advertisement 5, Hoarding • Radio spot • Message • TV spot • Announcement • News paper Ad • Ad in Periodicals 6, Novelties with Message • Key-ring 12. Print & Electronic Media • Carry-bag • Feature • Purse • Appropriate slot • Bust • Special article • Special programme [158] Use of Mass Media M ore and more people in the third world have been gaining access to mass media. Mass media in India are often poorly used as one way 'top down communication' in the field of blood donor recruitment However, with little imagination, it is possible to make effective supportive use of media to spread the message of blood donation. Mass media may be expensive unless the existing slots are effectively used. The 1990s is a decade of intense social change. The most important factors contributing to this change are increasing access of common people to modern electronic media. Radio is still the media channel that reaches widest audience particularly away from metropolitan cities. The following slots of TV/Radio can be used: • News items • Interviews • Spot announcement • Drama • Jingles • Quiz • Phone ins • Music • Discussions • Panel discussions There are an estimated 1050 million TV sets in the world. One for every six persons. Most of these are in industrial countries with one TV for every two persons. In the developing countries, particularly ir. cities and towns, there is one TV for every twelve persons. In Asia there is now one VCR/VCD for every seven TVs. In India more than 12000 VCPs have been fitted to long distance buses that travel between the states. Mass media messages tend to be general and are not always relevant to the needs of the specific community or groups. It is also difficult to be selective and target one particular age group. And, unlike face to face approaches, there is no direct feedback. But on the other hard if carried out well, mass media has the advantage of being able to reach a large audience rapidly and does not require an infrastructure of field workers. Although, many people prefer face to face communication, lack of time, shortage of field volunteers and difficulties of transport can make mass media a vehicle of communication but these have to be used with careful pretesting, evaluation and audience research, obviously with pragmatic planning. The mass media can help in creating awareness and in behaviour change, agenda setting, creating a favourable climate of knowledge and opinions suggesting action plan and conveying newer ideas [159] and concepts. The feedback of the programme should be obtained through survey, opinion poll and audience research. In Amambara state, Nigeria, 43 mini dramas on family planning were used in the popular variety show "In a lighter mood". During the period attendance at the major clinic in Enuga increased from 50 in a month to more than 120 in a month. After the first month, an average 45 percent of the visitors to the clinic mentioned the show as their source of referral. In a survey carried out on the streets more than half the people surveyed had. watched the programme the night before. More than two third of these people could give the address of the clinic mentioned in the programme In India, a soap opera produced, was called HUM LOG (our people that used stories about ordinary people to promote ideas of equal status for, women, family harmony and small family sizes, An average of 50 millior people watched 156 episodes spanning over a period of 17 months ir 1985-86. It was evaluated through a survey of viewers. Evaluation revealed that the first twelve programmes were not as popular as later ones. The earlier programmes put too much emphasis on family planning messages and not enough entertainments and establishing the characters for the drama. In Switzerland a six month radio campaign was run to promote home made oral rehydration solution. Twenty radio programmes of 15 minutes each, 46 radio inserts each of 5 minutes and 22 spot announcements were developed. A leaflet with mixing instructions was produced and poster were displayed at health clinics. Training workshops were held for health workers and participants in turn trained other volunteers. Local volunteer, were given yellow flags to hang outside their homes to show that they could help in treatment of diarrhoea. Evaluation of the campaign showed that 85 percent of the country's population had been exposed to the campaign, A survey before the campaign showed that only 15 percent could correctly make up the solution. After the campaign, this increased to 42 percent. In 1981, prior to first ever mass blood donation camp in West Bengal AVBDWB launched a three-month campaign: announcement of the programme jointly with the Indian Football Association, sponsored newspaper advertisement with coupons one month before the camp, display of posters throughout the state, sponsored hoarding, radio talks in sport slots, news write-up in sports page and announcement during the interval of charity football matches through the PA system of the stadium as also at intervals through running commentary on radio, distribution of 50 thousand ■ leaflets in a single day in a charity football match, decorating the stadium with colourful announcement posters requesting the TV crews to focus their [160] Educational Programme ;Sl"tK.f«ni'll'«i- live Reminder to Donors una Blut Motivational Materials Information Materials Just be a blood Donor screened blood Therefore old transfusion unless bsolutely necessary. n of whole blood !■ seldom us r,.,n*foie -*** btaod is Hot ii«tf»,iry rewdrbps4oi your Mood Educational Materials Touching the Heart camera on the posters while the important football match was in progress. On the day of the donation radio announcements from time to time communicated the latest number of donois. On August 16, 1981 there was no newspaper but there were 1208 donors. They came individually by using public transport, despite intermittent torrential rain. Next day, the press covered the programme through sports columns as it was a donation in the field of sports. The radio and TV made it an important local news. This camp has now entered into its twenty third year generating a large number of smaller camps by the individual donors of the day in their locality or place of work. Print media can play an effective role to propagate the news of blood donation, forthcoming blood donation programme, messages and articles on blood and blood donation by using appropriate slots without cost besides advertisements, special issues and supplements. Appropriate slots in print .media are: • News items ■ Letters to the editor • Feature articles ■ Health columns For all these, donor recruiters must maintain good rapport with media people. But media should be used judiciously. Over using media may have a counter productive effect. Constant Review & Evaluation Translating the vision In designing Communication Strategy — Message & Media Target Operational Programme Field Trials [169] Rework Feed back and Evaluation Donor Records I n all stages of activities of blood bank, various data are generated. It is essential to collect and store these data so that appropriate information can be retrieved as and when required for assistance to patients, planning, evaluation and research for donor recruitment programme. The objectives of record-keeping are: • To improve upon the day to day work of the blood bank • To help promotion of blood donation • To provide information of donors' profile • To monitor availability, distribution and utilisation of blood. All blood banks and transfusion centres usually have at least one thing in common, i.e., the volume and scope of their work tend to expand rapidly beyond the limits originally foreseen. It is important, therefore, that the record keeping should be systematically planned from the first day so that for expansion of activities, basic system or format need not be changed. For small blood banks, records can be maintained manually by registers. For medium size blood banks record keeping can be done by cardex system with appropriate cabinet or box; The best way, however, of modern age is to use computer . Now a days, most of the educational institutes have computer centres. Their facilities and human resources can be easily utilised by transfusion centres, blood banks and donor recruiting voluntary organisations. This will also involve the educational institutes with blood donation movement. From blood donors and donor organisers' side, the following data of donors are to be maintained in any of the three methods: • Name • Address • Telephone No. • Pincode . • Date • Bag No. • Camp Code • Age • Sex • Weight • Blood Bank • Group • Rh • Remark Each donor organisation can be allotted a numerical code so also the blood bank collecting blood. By designing a suitable computer coding sheet, all information can be collected for each and every donor, [170] By feeding the fourteen line data in a computer, all embracing donors' and donor organisers' directory can easily be maintained to give a number of systems and subsystems: Donors' Directory subsystem Apart from the classified particulars in the Donors' Directory files, it should also contain a short list of Rh negative donors who can be contacted in case of emergency. Promotional subsystem Designed to maintain contacts with the prospective and regular donors. Outputs of this subsystem are the various mailing lists, camps and organisations such as: • Mailing lists of regular donors who should be thanked, recognised or sent birthday greetings etc. • Mailing lists of prospective donors who will attain blood donation age in the following month. • Mailing lists for sending invitations regarding various functions, including blood donation camps on special occasions. The various reports that can be generated from the donors' directory are: • Negative donors list • Pincode-wise donors' list • Multiple donation record of donors and donor organisations • Collection pattern of blood banks • Sex ratio of blood donors • Blood group distribution in the community • Age distribution pattern of donors • Average body weight of male/female donors • Graphical display of all such data can easily be prepared. Classification of donor organisations and their days of blood donation camp would help in planning blood donation drives in the next year. Without proper record keeping, donors or donor organisations cannot be honoured. Honouring donors and donor organisations help in donor retention. The donors' directory may be utilised to meet emergency blood need, rare group patients' need, fresh blood need and also for inviting donors for subsequent donation after three months or at least once in a year and also for 10/25/50/100 donation awards. [171] Blood banks can easily maintain their record of storage, shelf life, requisition, blood bag movement, blood users' details by properly designing a coding sheet or their registers/cards/forms suitable for direct data entry in the computer. These data in turn would help in developing the following subsystems: Routine subsystem To provide information regarding the stock of various categories of blood and to provide timely warning if certain categories fall short of specified limit. The subsystem should also provide messages regarding the bags of which the dates of expiry have crossed. Analysis subsystem The objective of this subsystem is to use the information stored in various files and to provide a number of statistical report as: • • • Utilisation/wastage analysis Blood requisition pattern by doctors and for different medical/ surgical cases Seasonal changes in blood requisition. In each stage of donor recruitment, the motivators would need data. At the time of starting the work, available data of others or from other sources may be used and with the progress of work the motivators should develop their own data through a survey which should be checked and updated from time to time. Selection of appropriate sample for the survey plays a important role in deriving realistic inference. Deferral donors' list can also be maintained by using the same coding sheet by only adding the reason of deferral by using pre-determined coding number. The donors, temporarily deferred may be encouraged to come back to the main stream of donors on fulfillment of requisite criteria. Donor counselling record can also be maintained in a similar manner by designing a suitable coding sheet. [172] Quality Management in Donor Recruitment Q uality is never an accident, it is always the result of high intentions, sincere effort, intelligent direction and skilful execution of many alternatives. There are four universal steps to accomplishment: plan purposefully, prepare pragmatically, proceed positively and pursue persistently. People forget how fast a job was done - but they always remember how well it was done. Donor recruitment is the first step to any successful transfusion service. In our country, personnel in medical service are mostly taught to handle sick people, dying people and people hovering between life and death in conscious, semiconscious and unconscious state. But the transfusion services have to handle healthy persons as donors as well as anxious and perturbed able-bodied friends or relatives of patients across the blood bank counter in quest of the vital life saving fluid with sophisticated technology in between. Our view of quality in the world today is getting broader as the world around us is getting smaller. In this small world, owing to the advancement of information technology, sky is the limit of expectation but we must have the basic minimum in the country within the various constraints and limitations. The quality in donor recruitment obviously includes public relations, communication and the art of man management, psychology of intending donor, regular donor and patients' relatives, process control, training of personnel, statistical measurement and analysis of satisfaction of donors, users and patients' relatives. All these are based on science. The blood bank's path of work-flow begins with public relations, donor motivation, recruitment and retention and proceeds through blood collection, processing, storage, distribution and post transfusion follow-up and research. The quality at each stage directly or indirectly has a major effect on donor recritment and retention, because satisfaction of people in and around the system help in donor motivation and recruitment in the society. All activities in the light of quality assurance and process simplification can be monitored, reviewed and audited for compliance with standard for the Purpose of improvement. People seldom improve when they have no other model than themselves to copy after. The saying goes, that "there is always room at the top". The quality of a system or service is in direct proportion [173] to the commitment of the management to excellence. Unless improvement is attempted all the time, the system will have an inherent tendency to go down the stairs. In the quality system, the next operation in the path of work-flow is dependent on the output of the one before. Public education, donor recruitment and donor retention are the first three functions in the blood banking path of work-flow. Without the proper operation of these three functions, there will not be enough blood for transfusion to patients. Voluntary blood donors who offer their gift of love need to be handled with care at the collection drive as also the patients" relatives or friends in the blood distribution counter. These help in building up confidence of the community around on the transfusion service and in turn ensure the steady supply of blood from the voluntary blood donors for the next stage of the process. Quality of donor can be assured prior to donation through interview, self declaration and some simple testing and physical examination. Scientific donor screening helps in instilling confidence in the minds of prospective donors and at the same time ensures the quality of blood. But the quality of blood in totality can only be assured in the laboratory after collection and transportation. The laboratory testings are technical in nature. Their correctness and" credibility help in donor recruitment. Still., donor recruitment strategies mus float the idea of inducing all eligible persons to offer their gift of blood. The system at the time of scientific donor screening and laboratory testing wouk take care of quality to ensure safety of donor and safety of recipient. The donor must be motivated and inspired to donate blood voluntarily withou any coercion, compulsion, pressure and regimentation to endure a little bi of inconvenience and discomfort. While doing this, the function of the recruiter is to overcome the negative issues. This task requires skill, prudence patience, knowledge. There is no short-cut to success in this area of blood banking activities. Blood banks of this country suffer owing to shortage of blood by not paying much attention to this vital and fundamental area of service. The quality system approach for blood donation ensures that the process of educating and recruiting potential donors and retaining then provide the best quality of blood going into the blood bank. Naturally, the education of common people to donate blood shall include the parameter for awareness for self exclusion for the purpose of safety of both the donor and the recipient. Blood banks must have trained manpower to handle donors an [174] their donation for proper utilisation with adequate provision for monitoring, evaluating and quality assurance in all fronts to ensure blood safety. Planning of blood collection drive must take into onsideration: (a) the ability of the community to provide requisite blood donors, (b) capability of the blood bank to collect enough blood in a day and store to meet its need for at least seven days, (c) ability of blood bank personnel to recruit, collect, process, test, store and distribute blood following standard operating procedures (SOP). After the major functions are identified, they are analysed using the flowcharting. Process analysis on flowcharting demonstrates the way the process is currently performed. Another activity, called gap analysis, compares the way the process is carried on now to 'best practice'. Gap analysis of blood bank's current process to best practice identifies policies, processes or procedures that are missing and are needed for improvement. In a quality system the blood bank will actively determine the requirement of both the donor and the recipient so that it car. plan its process to accommodate their needs to the level of total satisfacticn. The needs include : • safe, satisfying blood donation experience on al counts, • sufficient supply of blood, • safe blood transfusion. This, in turn, will need planning and scheduling more than just sufficient number of blood donation camps to meet the reed of patients and hospitals. The donor recruitment function must deliver what it commits to deliver for each of the other functional areas to be successful to ensure blood safety. Statistical information on public education, donor recruitment and donor retention functions can be analysed to ensure the success of the activities of that particular sphere. Statistical measurements capture vital information on the percentage and type of donor defera the number of no shows, best days and times for the best turnouts for the group, the best donation sites and the features that make them successful, effectiveness of recruitment and promotional strategies including techniques and materials used. These can help in evaluation of the total programme with path correction and evolving strategies for both the near and distant future to achieve total voluntary blood programme by ensuring quality at every stage. [175] Community Based Organisations F or safe blood transfusion, a wide base of a large number of voluntary donors and a culture of voluntary blood donation in the community are required. To recruit and motivate people to donate blood voluntarily blood donor motivators and organisers are needed. A donor motivator cannot work alone. Naturally, suitable organisations are required to be built up to achieve a total voluntary blood programme for the country. The organisation can be an integral part of the transfusion service with aid professional people. In India, there are 1832 blood banks; one professional in each of blood bank is a drop in the ocean. The paucity of fundi .will restrict blood banks from bringing in the required number of peop to carry out projects in changing social attitudes. The fund constraints does not permit blood banks to induct the best persons for the job. These limitations can easily be overcome by establishing voluntary organisations. In some states, voluntary organisations with active involvement : of the community are working from outside the blood banks to motivate recruit and retain voluntary blood donors. There can be any number of organisations in the form of Society, Association. Clubs. Such organise ons may be voluntary but they can work with professional competence The organisations may be at state / district / subdivision level or one for each blood bank. One can see such organisations in Tamil Nadu, West Bengal, Gujarat, Punjab Chandigarh, Maharashtra, Tripura. Madhya Pradesh, Orissa and Delhi. The advantages of such voluntary organisation are: • Requires little funding as there is no salary and administrative heads. • Involves the community. • Can induct the best available persons for a particular job. • Helps in improving the quality of life of the volunteers. • Can embrace any number of volunteers by expanding the activities, both in the horizontal and vertical planes. • Manpower is the vital resource. • People well placed in life get a platform for implementing their ideas and innovative skills, thus deriving mental satisfaction. • Volunteers can choose their work according to their ability, skill and liking. • There is a place for anybody and everybody willing to work for the cause in this organisation. [176] The essential technique of running these organisations is the blending of the best of formal and informal structures honouring the classical definition of organisation, i.e., an organisation is the systematic arrangement of people working together towards a common objective, goal and purpose. There are four fundamental requirements for this type of organisation : (1) Work: product of careful thinking and planning based on objectives. (2) People: Who will carry out the activities. They must be well qualified and trained. (3) Organisational structure: functional set-up with coordination from the nucleus. (4) Working place: coordinating office. The executive committee elected by the members should meet to formulate the policies, to evaluate the feedback reports and to initiate path correction, if necessary. The informal volunteers' meetings would implement the programmes based on the policy laid down by the executive committee. The coordination and proper liaison between the executives and volunteers at all level would be needed for success of any programme so also with the blood banks. The volunteers would get the authority from the following sources: Authority given by the executive committee or the volunteers' meetings. • By virtue of position in the organisation according to the constitution, rules and regulations. • By personal acceptance as innovator or job-doer. • By recognition of skill knowledge or leadership qualities. • The objective, goal and target should be set up after deliberation, debate and collective decisions on the action to be taken today to obtain the desired result tomorrow. Activities should be based on anticipating and predicting the future. A balance should be sought to achieve between the Present means and future results. The organisation structure of such a novel organisation should be functional. A group of volunteers having more spare time than others should constitute the core or nucleus of the organisation. The coordination, monitoring, evaluation, path correction and overseeing all the activities should be in their hands. In times of extreme need, they may become fullvolunteers for a specified period for a particular project by taking leave from their place of professional work or engagement. [177] Another group close to the nucleus/core, but bigger than the former should undertake responsibilities of some fixed work by adjusting their free time according to their liking, skill and temperament. Out of 168 hours in a week at the disposal of every individual, the voluntary organisation can claim at least four hours per week from these types of volunteers. Another bigger ring of people - friends, members and associates surround the first two rings; they should be available on call for a very short time to undertake highly specialised work commensurate with their professional skill. They may work from their own place of work. Beyond these three rings there should be sympathisers from the community and friends of the movements who would consider the organisation as their own in view of their personal acquaintance with the volunteers of the first three ring of the organisation. They would act as ambassadors of the movement. With time, people from different rings may shift their position inwards or outwards. There may be dropouts with the passage of time. Health, family, transfers in the field of professional work or pressure of work would be the causes. They must be replaced by newcomers. New programmes would induct new volunteers. The volunteers are individuals, but they have to work together as a team. Such an organised group always has a distinct character. Though composed of individuals, their vision, their practices, their attitudes and behaviour, i.e., the character of the team is a common feature. The organisation, through various training programmes, should mould the behaviour pattern and attitudes of the newcomers to fit into the organisation in an effective manner. [178] The nucleus or core should fill in the gap whenever there is any. A leader of a particular work area should work as a volunteer in other areas and thereby dignity and importance of all types of work could be maintained. Small bits of work added together give birth to a big success. Recruiting better people in the army of volunteers is part of the regular process and culture. Since the volunteers will be coming from different walks of life, suitable training programme would be needed to make these volunteers worthy of the organisation. For conducting training programmes suitable resource persons from the society would be needed. Two sayings exemplify the spirit of these type of voluntary organisations. First is the Inscription on Andrew Carnaige's tombstone in USA: "Here lies α man Who knew how to enlist In this Service Better Man than himself The second is the slogan "it is the abilities, not the disabilities, that count". The focus of the organisation is always on the strengths of its volunteers and not on the weaknesses, because weaknesses of individuals do not exist when the organisation is considered as a whole. The following activities may be taken up by these voluntary organisation from outside the blood bank with success but with proper networking with other similar organisations working in the region and also with the blood banks: 1. Education of • Common People • Donor Motivators • Blood Users 2. • • • Motivation Seminar IEC Materials TV, Radio Programme. • School Students • Social Workers • Blood Bankers. •Exhibition •Newspaper Articles 3. Blood Donation • Regular blood donation camps • Occasional mass blood donation camp. [179] 4. Recognition of • Donors • Donor organisations • Donor motivators. 5. Database • Donors' Record • Rare group panel donors • Web page in internet. 6. Publications • Bulletin • Periodicals • Literature. 7. Organisation • Coordinating regular office • Sharing of expertise : State / National /International Seminars / Conferences / Colloquium. 8. Study and Research • Donors' profile Donors behaviour • Blood need • Use of blood • System analysis. These organisations cannot remain static. It needs periodic changes and modification according to future needs and situations in terms of objectives, and work and personnel. Otherwise the organisation would be in danger of losing its dynamism. With time the work should expand horizontally and vertically. Voluntary organisations should cause SWOT (Strength, Weakness, Opportunity and Threat) analysis and initiate action to plug loopholes, if any. [180] Leadership in Voluntary Organisations T he success of any voluntary organisation lies in the ability of its leaders to plan, organise, direct, coordinate and control its activities aimed at its mission to fulfil a set of well defined objective to reach the goal. Leadership can be defined as the activities of influencing people to cooperate towards some goal which they come to find desirable. In other words, leadership may be defined as the relationship between an individual and a group around some common interest and behaving in a manner directed or determined by the individual. Leaders have the task of visualising and harmonising the desires and the motives of those led. Thereby, they create better attitude, arouse enthusiasm, create improved morale and foster a spirit of cooperation. They use their personal influence to alter human behaviour. They are able to motivate people. The four basic leadership styles are: Style 1: Directing The leader provides specific instructions and closely supervises task accomplishment. Style 2: Watching The leader not only continues to direct and closely supervise task accomplishment but also explains, solicits suggestions and supports progress. Style 3: Supporting The leader facilitates and supports fellow volunteers' efforts towards task accomplishment and shares responsibility for decision making with them. Style 4: Delegating The leader turns over responsibility for decision-making and problem-solving to volunteers. In an ideal case all the four styles combined together make a perfect leader. In a voluntary organisation collective leadership instead of autocratic leadership is desirable as one can cover the other. It is a debatable question as to whether leaders are born or made. Research in behavioural sciences' has shown that leaders barring a few exceptions are not born but made. Even though personality traits and habits [181] tend to be stable, yet all of us change our behaviours, though not basic personalities. Therefore, there can be training programmes for the leaders of the voluntary organisations which may have two wings (i) value inculcation (ii) skill development. The question - “what makes a leader”, has been asked by many. The question has been answered at political revolutions, mass movement or socio-economic field. There are exceptional leaders who make history such as Gandhiji, Netaji Subhas Chandra Bose, Swami Vivekananda, Abraham Lincoln, J R D Tata and many others. Every system and organisation need leaders. A leader of the voluntary organisation will move the organisation rather than be moved by the organisation. Here are few a qualities and characteristics of the leader: • A sense of purpose and direction • Willingness to act • Sensitivity to and interest in fellow volunteers • Demands more on self and keeps on growing • Powerful convictions • Emotional strength to keep stable under stress • Ability to differentiate between the significant and the insignificant • Attaching faith, trust and confidence on fellow volunteers • Have resourcefulness and ingenuity • Flexibility to adopt to the community’s needs and demands • Ability to develop a team. It must be remembered that leadership in a voluntary organisation is concerned with values, issues and motivation. Leaders have to take a stand, have to take risks and have to anticipate and initiate action often in a innovative way. Effective leaders of voluntary organisations are not commanders or controllers or bosses but are servers, supportive partners and providers. This type of leadership unleashes much more energy, talent and commitment from the volunteers which the commanding and controlling types cannot. There are seven basic principles of leadership known as seven ‘I’s: • Insight: Self awareness, understanding others and seeing the situation. • Initiative: Taking responsibilities and risk to direct action with vitality. • Inspiration: With vision, trust, appropriate communication and passion. • Involvement: Enrolment, experiment and feedback. [182] • Improvisation; • Individuality: • Implementation: Creativity, flexibility. Style, personal experience, values, integrity, neutrality. Action minded, perseverance, model behaviour. Thus the leaders of voluntary organisations have to achieve the task, building and maintaining team and developing the individual. The seven ‘I’s are a useful way of remembering the seven leadership principles. They also highlight perhaps the most powerful part of effective leadership. Last but not least, the leaders of voluntary organisations should be successful volunteers first and work with the volunteers hand in hand as one near and dear to them. Ultimately, on the ability of team building by the leadership of voluntary organisation, depends the success of any programme provided the programme is specific, measurable, action oriented, realistic, time and resource bound. “The great difference between the real leader and the pretender is that the one sees into the future, while the other regards only the present; the one lives by the day, and acts on expediency; the other acts on enduring principles and for immortality”. - Edmund Burke “A leader takes people where they want to go. A great leader takes people where they don’t necessarily want to go but ought to be”. - Rosalyn Carter [183] Handling Errors and Complaints Errors accompany us everyday in our lives. Most of them are annoying although rarely serious or fatal, others are neutral, and a few may result in a happy finding. Sir Alexander Fleming discovered penicillin as the result of an error, most of the genetic mutations (errors) produce aberrant consequences, but some of them represent a progress. Our attitude towards errors should be a mixture of fear and curiosity. To hide an error is an additional mistake, because error study is a fruitful source of knowledge on the one hand as its analysis is the right first step in order to prevent its recurrence, and on the other hand we can learn something about unexpected and positive features connected with an error. Quality programmes include error management systems designed to detect, investigate, neutralise the effects, and correct errors. Entropy (degree of disorder inside a system) is a quantity studied in Thermodynamics. A physical principle states that entropy grows on and on continuously unless something is done against this growth. This also applies to everyday life, even to blood donation. Programmes and tasks that work well should be actively maintained. Otherwise they would deteriorate little by little through everyday erosions. Error categories What is called an error in a broad sense may be subdivided into categories: Errors are the result of a problem badly handled or the result of a mistake of human origin. In most instances, the consequences are unacceptable products or services. Deviations occur when the method followed does not match exactly with what the accepted procedures say. Many deviations do not result in unacceptable products or services, but all of them should be studied, the possibility of adverse effects should be determined, and measures should be implemented to avoid its recurrence. Audits are the best tools for detecting deviations. Accidents are unexpected events which differ from the errors in their non-human origin. In these cases, the right procedures have been followed but something has interfered in the method. Complaints come up when the user returns a faulty product or requests an explanation related to what has been considered a bad service [186] Not always a complaint is equal to an error, but all the complaints of blood donors should be investigated. Negative trends are the result of an analysis in which a deteriorating situation is detected but clear cause or causes cannot be determined. If the problem is not with an element or a set of elements of the system but their performance as a whole (structural), then we should speak about crisis. Error management As stated above, errors should be detected, investigated and their adverse effects should be neutralised and their recurrence must be prevented. To achieve these goals, the system should be accessible and used by all appropriate members of the staff or volunteers. Strong emphasis must be put on the positive aspects of error management. The whole system works on documented basis: written procedures, records, written reports, documents, audits, etc. Error management in blood donation Elements Usually, a single error management system operates in the whole organisation, ordinarily managed by the quality department. Nevertheless, we shall see how the system may be applied to the particular situation for the promotion of blood donation. The following elements should be put in place: 1) Complaint files. All written and oral complaints received must be recorded and all the data gathered with the type of complaint, source, circumstances, name of the person who received the complaint, etc. The records should be forwarded to the appropriate person in order to be investigated in depth. The results of the investigation should be recorded. A reply to the complaint should be ready as soon as possible. Usually the reply is done in two steps. Within one or two working days a first reply may be addressed to the donor (either the donor or the organisation in which the donor session takes place), and in a period not longer than fifteen working days, a full reply should be completed. The replies must be recorded. 2) Written procedures shall bear instructions regarding the method to be followed in each type of error and circumstance: what should be done, in which order and period of time, by which person should be replied to, etc. In general, the following steps should be included: - Detection of the error. Record. - Magnitude of the problem. Immediate action to be taken. [187] - Documented in-depth investigation. Report. - Preventive/corrective measures to be included in the system. - Once corrected, review the system to see if it works. 3) Written records. It is essential to maintain good records from the beginning. An unimportant detail may be the main clue to the problem, this happens quite commonly. Moreover, written records allow a study of the trends and form the basis of the management review in the organisation A form accompanied by a pre-written questionnaire may be a useful tool in the error management system. Other elements may have a role in error detection. For example, an opinion poll (easier and more interesting to be done on donors than on non-donors or general population) may include direct questions related to different aspects of the blood donation and how it is perceived by the donor. This source of information has an additional value of qualitative nature as long as one may know the donor’s point of view expressed by herself himself. Methods From the practical point of view, blood banks ideally should manage errors following two schemes, one for complaints or observations coming from outside, and another for quality incident reports of internal origin The main difference between them is that every complaint must be answered in a timely manner, a matter being of paramount importance. As long as errors are registered in a book, it is useful to keep two books, one for complaints and another for internal incidents that makes it easier to control the follow-up of complaints in the first book. A very few centres manage lesions and injuries done to blood donors during or after the phlebotomy following an alternative specific method for registration. An ad-hoc form for handling this kind of error is filled with answers to specific questions. A complaint form, an internal incident report, a donor lesion form, should be completed in three steps. The information related to the error itself should contain what happened and what was done immediately. This is usually completed by the persons who had a direct contact with the error. Recording of matters related to the study of the error should have the information about - What were the causes? Are they likely to happen again. What could be the consequences? Is it necessary to take corrective actions If necessary it should be stated that measures (if any) have to be implemented. [188] And finally every error should be specifically closec. This means that someone reviews the records related to the error, the implemented measures, the answer given to a complaint, etc, and agrees that the error has been cleared up. The donor motivators have to face new donors as well as old donors. In motivation sessions, he/she may have to face questions / statements / complaints regarding the real / apparent / pseudo errors of blood collection team or blood bank personnel. He / she must have first-hand knowledge about handling problems out of error by his / her blood bank or organisation. In some cases donor motivators can be error resolvers too. In effect, error management is part of the quality system in Transfusion Medicine, and consequently in blood donation. Well-handled errors may be a fruitful tool to improve the quality besides the mitigaton of the negative consequences of the error. Standard Operating Procedures QUALITY ASSURANCE Quality control external Audit internal external Training “Meaningful work, mutual respect, honest communicator!, continuous learning - are the ingredients that stimulate men to improve in personal competence and meet the future with confidence. When these needs are suppressed, human resources dry up; men become only a fraction of what they could be”. - Rohrer Hibler [189] internal Evaluation of Blood Donor Motivation Programme Any programme involving Man, Method, Material, Money and Management would require periodic evaluation, monitoring and path correction with due regard to the objectives of the programme. Blood donor motivation, recruitment and retention are complex subjects involving the above mentioned ‘M’s and naturally the programme should be evaluated from time to time. Among all the items, manpower is the main resource and should be considered as a costly item of the system warranting judicious, effective and productive use. If the effort and time spent are not commensurate with or proportionate to the results achieved, it may lead to frustration, particularly if the effort put in is voluntary in nature. This in turn, may lead to drop out from the work force causing harm to the cause. In India finance is a constraint and as such each paisa should be properly spent and accounted for. There is a rule of thumb to evaluate social welfare and awareness programme. How much portion of a rupee of the budget goes to the direct service or awareness head? Higher the apportionment for the salary and administrative expenses, the less effective will be the service area. Cardinal evaluating factor for any donor recruitment and motivation programme will be the number of voluntary blood donors actually recruited and retained. For long term programmes such results may not be immediately perceived but if the long term programme is effective, it must have a direct palpable effect on the community. The subject will crop up in everyday vocabulary, colloquial use, literature, poems, drama, news, songs, jokes. TV and Radio programmes and even in question papers of educational institutions and interviews and tests for jobs. Study on blood donor recruitment programme may be undertaken to evaluate the end results. The indicators for evaluation may be: • Number of units of blood collected from voluntary blood donors. • Proportion of donors who are voluntary non remunerated community based with respect to total blood collection. [190] • Yearly reduction in the number of replacement donors. • Proportion of blood donors who are regular repeat donors and proportion of new donors. • Proportion of women donors. • Proportion of one time donors. • Number of blood units collected per session. • Actual collection per camp with respect to the arrangements rnade. • Proportion of blood discarded after collection for markers of transfusion transmissible infections. • Proportion of deferred donors. • Proportion of donors self deferred after going through the literature in camp. • Number of organisations and trained volunteers working in the field. • Level of increase in blood donation following motivational programme for different groups. • Number of organisations accepting blood donation as their regular routine activity. • Number of schools accepting blood programme on their own. • Number of school visits undertaken. • Number of news/articles/feature on blood donation coming out in print or electronic media. • Number of stalls on blood and blood donation in fairs or exhibitions. • Number of requisitions honoured by the blood bank. • Number of requisitions refused by the blood bank. All these data can be obtained by field study and using proper questionnaire. Even the oral presentations in motivation sessions can be evaluated by conducting a survey among the listeners. IEC materials can be evaluated through personal interview and opinion poll. All these are integral parts of donor recruitment programme. It should be an in-built concurrent procedure alongwith voluntary blood programme. [191] Research in Blood Donor Recruitment Blood Banks can be gold mines of academic-minded research workers, social scientists and donor motivators. Through research work or research data of their own or of others, the motivators can develop newer technology of donor recruitment and make the path correction. They may even do away with fruitless unproductive exercises. The most important studies would be knowledge, attitude and behaviour pattern of community towards blood banks and blood donation. Strength, weakness, opportunity and threat (SWOT) analysis of blood banks and donor recruiting organisations can be the basic areas of research. Deferral of donor and discarding of blood after collection can give an idea of the status of donor group. Donor recruitment with respect of recruitment strategies and techniques and in expansion of blood donation movement with time can be an useful area of research. The blood group distribution pattern of blood donors of the region would be needed to determine maximum level and minimum level of stock in blood bank shelves to meet all requisitions irrespective of blood group. The research workers can provide these types of information to blood transfusion service. Quality of blood supplied by different target groups and their convenient day and time of organising blood collection drives would give an insight to the donor motivators to have their blood collection programme evenly spread throughout the year. The study of blood requisitions from clinicians and surgeons may give data about the rational use of blood. All research workers will need proper training with knowledge about the land and people, data collection, structured or unstructured interviewing of people, scientific representative sample selection, blood banking service including its technical aspects and ability to interpret the data generated from different sources. Effectiveness of lEC materials in changing behavioural pattern of the society can constitute an area of research. [192] Starting point of any investigating research work in the field of blood donor motivation, recruitment and retention is planning in a systematic, logical manner as hereunder: Review existing information Define general procedure to follow before starting the investigation Define existing objectives of research Define general procedure to follow before starting the investigation Define scope and objectives of research Define chronogram Define research questions Select and train research learn Choose appropriate methodology Choose techniques and develop instruments Define sample and select sites One of the most important phase of formative investigation is data collection. During this phase, an order is found and a better understanding of the subject is attained. This understanding, however, cannot be gained without the effort, persistence and determination of the research team. Steps to implement a formative investigation Implementing the Investigation • Data collection • Supervision. Organising and Analysing Data • During data collection • After completing the data collection • Writing the report. It is necessary to prepare a written report to present the results of the investigation. The report should contain: • Table of contents • Abbreviations [193] • • • • • • • • • • Executive summary Introduction Objectives Description of the study Methodology - Sample selection (units and segments) - Techniques and instruments - Selection and training of the research team - Duration of research - Limitations Results Discussion Recommendations Bibliographical references Appendices. When writing the report the final product and its use must be kept in mind to ensure appropriate specific recommendations. It should be remembered that the information is going to be used as a basis in the development of strategy with a purpose of increasing the number of voluntary donors. Writing the report by sections usually makes the task more simple and efficient. The easiest section can be written first and then writing the more difficult ones can be undertaken. The use of tables, charts and other graphics help to transmit information in a clear way. Quotes of the notes taken during the investigation give life to an idea and help illustrate specific aspects of research work. Research Area for Motivators • Blood group distribution of region • Participation of different groups in the region • Age group of the donors • Discardation of blood after collection • Myths and misconception about blood donation in the community [194] Modern Technology in Donor Motivation Starting point of any voluntary blood donor recruitment programme requires trained human resource - the donor motivators. The dedicated willing pairs of hands and legs can do miracle in transforming non-donors to donors and one-time donors to repeat donors without any modern gadgets. But with the development of the movement, Telephone, Computers, Email. Fax. VCR, DVD can judiciously be used for communication, record keeping and data retrieval. Motivators should appreciate that the above mentioned gadgets have neither any heart nor brain. They are made by man, to be used by competent human beings for the good of the society, and are not substitutes of human donor motivators having their heart at the right place and brain to innovate newer ideas and strategies to recruit and retain voluntary blood donors to achieve the cherished goal of a blood transfusion service totally dependent on voluntary blood donors. Use of computer in blood donor recruitment has been dealt with in the chapter ‘Donor Records’. Computer network can maintain inter blood bank contact and exchange of stock position. Email, fax, telephone including mobile phone can help in informing, reminding and contacting blood donors. Internet may give information from home and abroad while floating queries to get appropriate answers from far and near. One question is often raised: what is the future of blood donation? This question was provoked in the past by the continuing fascination with the idea of artificial blood. The term “artificial blood’ is used only for substances intended as a substitute for the oxygen-carrying functions of red cells. There are two principal approaches to this endeavour haemoglobin and perflurocarbon. The former has not been demonstrated to be safe. The later has many unsolved problems of toxicity and instability. Both can have, at best, a brief clinical effect because their survival in circulation is less than 24 hours. It must be concluded then that there is yet no blood substitute in sight which could take the place of red cell. There is also no early prospect of a substitute for platelets. Factor VIII is the only blood product which has an imminent prospect of replacement; two recombinant DNA products have been used in patients with haemophilia with promising results. [195] However, it remains unclear whether production on an industrial scale will succeed, whether these products can be produced at a cost which can compete with plasma-derived factor VIII and, indeed, whether recombinant products have any real advantage. All indications are that human blood will continue to be needed for the foreseeable future and that voluntary blood donors will continue to be the primary source for whole blood, components and apheresis, even in the third millennium. In spite of modern sophisticated gadgets, the oral communication in donor recruitment should remain the most effective tool for years to come and modern technology will play the second fiddle to support the motivational activities. The motivator should build up a flair for the prudent blending of the proven old techniques proportionately with the induction of beneficial modern technology to become really successful in donor motivation recruitment and retention in this era remembering that ‘old order changes giving place to the new’. [196] Land and People Enveloped by the ocean on three sides and cut-off by mountain ranges from the rest of Asia. India has all times enjoyed a marked geographical unity. The dominant geographical features which stand up in relation to this area are the high and impenetrable wall of the Himalayas which provide the Gangetic Valley with its great river systems; the Bindhya which divides the country and separates the peninsula from the plains of North India; and the Great Indian Desert which is a projection of the arid regions of West Asia almost to the heart of India. While the Gangetic plain is well watered by its perennial river system of the Ganges and its tributaries, the Deccan plateau is an upland where, broadly speaking the rivers become irrigable only at their deltaic mouths. India also presents a variety of climates which give to the country its continental character. From the Himalayan regions with their perpetual snows to the torrid heat of the South. India possesses every kind of climate. Another geographical feature -the seasonal trade wind, the monsoon, blows across the sea and reaches India with almost mathematical regularity in May and traverses the country in June and July. It brings with it rain laden cloud which water practically every part of India in varying degrees and return to the sea in September and October. Ofcouse, coastal areas of the east beyond the Bindhya have double monsoon. Not only has the economy of India been dependent on the regularity of this rain fall, but from early times the monsoon winds helped to make peninsular India a center of maritime communications. Not much is known of prehistoric man in India. The Harappans, as these proto Indians have come to be designated, lived in well-planned cities with a very good system of drainage. Their houses were commodious and made of baked bricks. They knew the use of gold and precious stones and seem to have cultivated cotton and wheat. The humped bull, the sheep, the elephant and camel had been domesticated. The harbour that has been excavated at Lothal in Gujarat proves that they were a sea faring people, who probably had established connections with the ports of Sumer. The destruction of Harappan civilisation was the result of the Aryan invasion. Many of the religious practices and speculative doctrines of these early Indians inspite of destruction of the old civilisation, such for example as Worship of Siva and the mother goddess, have survived in the Hinduism of today. The settlement of nomadic, pastoral of the Aryans in India, their [197] culture, the Vedas, the Ramayana, the Mahabharata, the Bhagvad Gita the Upanishads could put India in the global map by the fourth century B.C. as a highly developed civilisation. Then invasion after invasion from the Greek to conquering of the country by the Britishers with Hun and Muslims in between inter spaced by Pallav, Chalukya, Rajputs, Maratha and Hindu medieval periods had social, cultural effect on the country. Indian population is polygenetic and is said to be the melting pot of various races. At present India has officially eighteen recognised languages. India is believed to have 1652 mother tongues, of which 33 are spoken by people numbering over a lakh. The Indian languages now in use have evolved from different language family corresponding more or less to the different ethnic elements that have come into India from the dawn of history. India has an area of 3,287,263 sq km and population over 1 billion with 28 states and six union territories and one National Capital territory. The blood donor motivators must have or acquire knowledge about the country in general and region of their work in particular. They must have knowledge about: population of the region, sex ratio, birth and mortality rate, literacy rate, child mortality rate, age group distribution, occupation of the local people, per capita income, local festivals, tourist spots, cultural traditions, history and geography of the region, hospital bed strength, health of the region and the medical history of the country. Handbooks on the country, census report, publications of Health Department and National AIDS Control Organisation would provide all these information. Naturally, such books should be needed for the library of the blood banks or donor motivating units or organisations. “The importance of Indian literature as a whole consists of its originality. When the Greeks towards the end of the fourth century B C. invaded the north-west, the Indians had already worked out a national culture of their own, unaffected by foreign influences. And in spite of successive waves of invasion and conquest by Persians, Greeks, Scythians, Mohammedans, the national development of the life and literature of the Indo-Aryan race remained practically unchanged and unmodified from without down the era of British occupation. No other branch of the Indo-European stock has experienced an isolated evolution like this. No other country except China can trace back its language and literature, its religious beliefs and rites, its dramatic and social customs through an uninterrupted development of more than 3,000 years. - Professor Macdonell in his ‘History of Sanskrit’ [198] Common Questions and Answers Q.1. Why is one not allowed to donate blood before attaining the age of 18 years ? Ans: Physiologically there is no harm if one satisfies otter conditions for blood donation. 18 being the age of consent in our county, the reason is legal. Q.2a. Can one donate blood after 60 years of age if he/she is physically fit? Ans: Yes, medically speaking, there would be nothing wrong. Q.2b. Then why people above 60 years of age are net allowed to donate blood in India? Ans: With ageing, blood vessels start constricting. Bloodletting from constricted veins may lead to unnecessary pressure on hear resulting in many physiological problems. It is not known at what age blood vessels start constricting. It varies from individual to individual. Therefore, arbitrarily the retiring age is considered as the age of cutoff for blood donation. Q.3. Can one donate blood if one’s body weight is lessthan 45 kg? Ans: Not desirable. But in extreme emergency, a margial difference in weight to the tune of 1 to 2 kg is not harmful, so long as body weight x 8 ml is above or equal to the volume of donation. Q.4. Why blood is not collected from a person having a haemoglobin content of less than 12.5 gm/l00ml? Ans: The stipulated haemoglobin content of 12.5 gm/100 ml for a donor is the standard for a healthy person. Persons having lessHb content than the prescribed one cannot be treated as healthy donor having sufficient Hb for donations and hence are not allowed to donate blood. Further, blood weak in Hb content does not help the patient much in carrying oxygen to cells. Q 5. Why 3 months’ interval has been stipulated though donated blood is recuperated within 21 days? Ans: As an additional precautionary measure for safet of donor. [199] Q.6. What physical tests are performed before blood donation? Ans: • • • • Weighing Hb estimation (copper sulphate solution method) Measurement of blood pressure Checking heart beats, condition of liver, lung and spleen. Q.7. What laboratory tests are performed in blood bank for each bag of collected blood? Ans: • • • • • • Jaundice (Hepatitis B & C) Malaria HIV (AIDS) test Venereal disease (STD) Blood Group Before issuing blood, compatibility tests (cross matching) are done. Q.8. Why the above laboratory tests are not performed before donation? Ans: They are time consuming tests, and if performed in camp before donation, there will be excessive delay in disposal of donors, and the disgusted donors may leave the camps and refrain from donating blood for ever. Besides, post donation tests are mandatory. Q.9. Blood is collected from a vein. Naturally, it is rich in carbon dioxide content. What purpose does it serve? Why is blood not collected from an artery to get blood rich in oxygen content? Ans: Though the blood collected from a vein is rich in carbon dioxide, it is transfused in the vein of the recipient and is automatically oxygenate in course of normal circulation and therefore serves the required purpose. Blood is not collected from artery for the following reasons: • Veins remain in the upper surface of the body muscle and can be easily identified while arteries remain in the subsurfaces and therefore cannot be easily identified. • Blood pressure in vein is low compared to that in artery. Puncturing of artery causes bleeding at higher pressure and velocity leading to trouble in stopping the bleeding after donation which is not a problem in case of vein. It is easier to pierce a vein. [200] Q.10. Is there any chance of contracting blood communicable disease by donating blood? Ans: No, since sterilised disposable bleeding sets areused. Q.11. What is AIDS? Is there any chance of contracting AIDS by donating blood? Ans: AIDS is an abbreviation for Acquired Immuno Deficiency Syndrome, which reduces the inherent power of the defence mechanism of human body. As a result, the affected person suffers fromother ailments, which may be fatal. No. there is no chance of contracting AIDS by donating blood, since disposable bleeding sets are used. Q.12. Will my blood group be the same as that of either of my parents? Ans: May or may not be exactly. But there should be a sort of relationship. We inherit our blood group from our parents by random combination of one gene from each of the parents. Dominant genes (A, B) prevails over recessive gene (O). Q.13. Does the blood group of a particular person change with time? Ans: No. Q.14. What is Rh factor? Ans: Rh factor indicates the presence or absence of an organic compound in the membranes of red cells of human blood, similar to that present in the membrane of the red cells of Rhesus Macacusmonkey. Those having the compound are denoted as Rh positive and those without such compound are denoted as Rh negative. Q.15. How long can blood be preserved in a bloodbank? Ans: In India blood is normally preserved in blood bank for 35 days using CPDA or CPDA1 solution as anticoagulant. Q.16. The maximum life span of RBC is 120 day. Why is then blood is preserved in blood bank for only 35 days? Ans: Donated blood contains cells ranging from 1 to 120 days’ life span. Naturally, cells having such varied life spans cannot be preserved for 120 days in the bag since in that case there will only be a few living cells Present. In order to get a considerable number of living cells present in the blood for transfusion, 35 days shelf life has been found to be optimum with [201] CPDA and CPDA1 solution on the basis of various experiments. Furthermore, cells which can remain alive for 120 days within the human body cannot survive for such period in an artificial environment. Q.I7. Will there be any good if blood is transfused to a patient on the 34th day after collection from the donor? Ans: It will serve the purpose of volume expander. There will still be a considerable number of living red cells present in the bag which will be able to carry oxygen to the cells and bring back carbon dioxide. Q.18. The blood collected from the vein may contain dead cells. Will there be any good by transfusing this blood? Ans: The blood collected will contain cells of various life spans. A considerable portion will certainly be living cells which will serve the purpose. Q.19. Often on tendering the blood donor’s card, blood is not being made available from the blood banks and then what is the use of donating blood? Ans: Donation in the real sense of the term is unconditional and without any string. Further, the credit card is given to the donor as a recognition and to meet the donor’s own future need or the need of the donor’s near relatives, who have no other alternative but to depend only on the donor to meet his/her blood need. It is expected that 10-15% donor cards would be tendered. If all the cards are tendered, then blood banks would not be able to honour cards in view of existing gap between demand and supply, as blood banks have to issue blood to serious patients also who have no cards at all. One should remember blood donors are not depositors. If there are enough donors, everybody should get blood in time of their need. Q.20. Why commercial blood banks are not being banned by legislation? Ans: Without organising voluntary blood donor base and the culture of voluntary blood donation in the community, mere banning of commercial blood banks will not solve the problem. Rather, the actual gap between the demand and supply will only lead to the establishment of more illegal commercial blood banks. Q.21. Is it true that the donated blood in blood bank is wasted unused? Ans: No it is just a myth and the story is cooked up by vested interest. Question of wastage does not arise when a big gap between demand and supply exists. [202] Q.22. Is there any corruption in blood bank? Ans: So long as there is a gap between demand and supply and people are afraid to donate for their near and dear ones, chances of corruption may be there. The only way to combat possible corruption in this specific area is to step up voluntary blood donation in a big way. Q.23. Which are the states of India where blood donation movement can be palpably felt? Ans: Maharashtra, Gujarat, Delhi, Tamil Nadu, West Bengal and Chandigarh, Punjab, Haryana at present. Q.24. Which country of the world has the best blood transfusion service totally dependent on voluntary donors? Ans: U. K., Canada and Australia. Q.25. What is the blood need of India and how is it met? Ans: 8 million units per year. Total collection is 4 million units. 2 million units by voluntary donors, 2 million units by relative and exchange donors. Q.26. What is the harm if blood donation is made compulsory? Ans: It has been observed that common people are apathetic to compulsion. The people should be motivated and inspired to donate blood voluntarily. Compulsion may lead to hatred towards the cause, which does more harm than good to the movement. Only sustained painstaking motivational programme based on education can help the country to achieve total voluntary blood programme. Moreover, blood collected from people donating under compulsion may not be safe. Q. 27. We have read in the science journals about artificial blood. What is it? Can it be used for transfusion as a substitute for human blood? Ans: The research is still in a preliminary stage. The term ‘artificial blood’ is a misnomer as blood has various functions. The so called ‘artificial’ blood can only carry oxygen to the cells and bring back carbon dioxide in a limited way but cannot perform any other function of blood at all. Further, this so called substitute is quite costly. Q.28. Why does blood coagulates when it comes outside the body out do not coagulate inside the body? Ans: Secretion of heparin by WBC inside the body prevents blood coagulation. But when tissues are wounded resulting in bleeding, a series [203] of reactions takes place in the bled blood which ultimately forms a fine mesh of hard fibre within which the blood cells are trapped and the blood is thus clotted. Q.29. Who can give blood? Ans: Anyone between 18 and 60 years of age and in normal health having a body weight of 45 kg. or more and a haemoglobin content no less than 12.5 gms/hundred ml can be a donor. Q.30. Does it take long time to donate blood? Ans: It should take up not more than 20 minutes of time including time for rest and taking refreshment. Q.31. How much blood do you take? Ans: Blood banks take only 350 ml of blood as your gift of love. Q.32. Why is my finger pricked before donation? Ans: To estimate “haemoglobin” content in blood. This is the component of the red cells which transport oxygen in the human body to all the organs and tissues. If the level is low, it is not wise to give blood. Q.33. What is the liquid in the bag into which the blood is taken? Ans: It is called anti-coagulant and prevents the blood from clotting. It also helps to preserve the blood cells. It is known as CPDA (Citrate, Phosphate, Dextrose, Adenine) solution. Q.34. How often can one give blood? Ans: Not more than once in 90 days. Q.35. Is blood donation very painful? Ans: No. Not more than a prick of an injection needle. Q.36. Will I feel all right after donation? Ans: Yes, you can go back to your normal work after 30 minutes. Q.37. I have heard of people fainting. Is that common? Ans: Very occasionally a donor may faint. The most common reason is psychological and often due to rushing to get up too soon after donating. Relax and rest a little and you will be fine. [204] Q.38. You wouldn’t want my blood, would you? I am of a common group. Ans: We constantly need donors of all blood groups. Q.39. Nobody has ever asked me to donate blood. Ans: Consider yourself invited! Q.40. I am too old! Ans: If you are between 18 and 60 years and in good health you can donate blood. Q.41. But l am underweight! Ans: Not, if you are 45 Kg. or more, and in good health you can donate blood. Q.42. Oh! but I am anaemic! Ans: We test for anaemia before every donation. Q.43. But it will make me weak. Ans: Blood donation has no ill effect on the body. You can resume your routine duties immediately after blood donation. The amount of blood donated is a small part of your surplus blood and is recouped by the body in twenty one days and you can donate blood again after 3 months. Q.44. I am too busy and it is too inconvenient! Ans: The entire procedure of blood donation takes about 15-20 minutes whereas the actual Blood Donation is just 5 minutes job! Q.45. How long does it take to transfuse a unit of blood? Ans: This depends on the condition for which transfusion is being given. If the patient is being transfused to replace blood for sudden massive blood loss, one unit of blood may be given rapidly in about 10-15 minutes. However, if the blood transfusion is being given for anaemia, it may take over 3-4 hours. Normal rate of transfusion is 28 drops per minute. Q.46. Can I develop a serious reaction to blood transfusion with blood from another person? Ans: Not usually. People differ from each other with respect to their blood groups and blood of compatible group is only transfused. Before blood transfusion, a sample of the blood is tested, and cross-matched with [205] a suitable donor unit. These tests reduce the risk of any serious reactions Of course, no medical procedure is absolutely hundred percent safe. Most blood transfusion reactions, if they occur, are mild. There are so many unfounded ifs and buts against blood donation that donor motivators should equip themselves with appropriate polite scientific answers [206] References A. publications of World Health Organisation 1211 Geneva 27 Switzerland or World Health House Indraprastha Marg, Ring Road New Delhi- 110 002 1. Safe Blood and Blood Products Module I, WHO/GPA/CNP/93. 2B. 2. Strategies for Safe Blood Transfusion – Dr ZS Bharucha and others. 3. Blood Transfusion: A Basic Text - Dr. Anthony F H Britten, Dr F A Ala, Dr Mohammed EL Nageh. Indian Authorised Edition available at AITBS Publishers & Distributors, J-5/6 Krishnan Nagar. New Delhi 110051. 4. Management of Blood Transfusion Service - Dr S R Hollan, Dr W Wagstaff, Dr J Leikola, Dr F Lothe. 5. Guidelines for the Organisation of a Blood Transfusion Service - Dr W N Gibbs & Dr. A F H Britten. Authorised Indian Edition available at B I Churchill Livingstone Pvt Ltd., 54 Janapath, New Delhi 110001 6. Recruiting, Educating and Retaining Safe Blood Donors, WHO/GPA/ BLS/95. 7. Safe Blood Starts With Me .......Blood Saws Lives. 8. Developing a National Policy and Guidelines on Clinical use of Blood. 9. Safe Blood and Blood Products, Costing Blood Transfusion service, WHO/BLS/98.8. 10. Guidelines for Quality Assurance, Programme for Blood Transfusion Service. 11. Consensus Statement on How to Achieve an Adequate Blood Supply by Recruitment and Retention of Voluntar, Non-remunerative Blood Donors, WHO/LBS/93.2. [207] B. Publications of International Federations of Red Cross and Red Crescent Societies: P.O. Box 372 CH 1211 Geneva Switzerland. 12. Quality Manual. 13. Development Manual. 14. Making a difference Recruiting volunteers, non-remunerative blood donors. C. Publications of American Association of Blood Banks Bethesda Maryland 20814 - 2749 U.S.A 15. Motivating Blood Donors in Today’s World: Recruitment and Retention - Lorraim, Kohr, Merlyn Sayers. 16. Donor Recruitment: Strategies For Success - Carolyn P Mihalko and Leslie A Botos. D. Publications of Council of Europe / European Commission BP432 RF 67006 Strassbourg Cedex France / or Rue Alcide de Gaspe L - 2920 Luxembourg. Director General for Development Health and Family Plannings AIDS Unit, Rue de la Loi 200 B 1049 Brussels Belgium. 17. Safe Blood in Developing Countries Principles and Organisation - Dr. C Gerard, Dr D Sondag Thull, Dr EJ Watson-Williams, Dr L Franser 18. Safe Blood in Developing Countries: The Lessons from Uganda - Re. Winsbury. 17. Mass, Media and Blood Donations - U Rossi, I Cipriani, V Fresia. F. Publications from Other Sources 19. The Hand Book For Blood Donation in Practice - Dr Gregor Veltkamp General Sckratarrat Post fach 45030 D-12172 Berlin Germany. 20. Blood Transfusion and the Challenge of AIDS in Greece - Dr Costantina Politis. Dr Johon Yfantopoulos. Beta Medical Publishers Ltd., 3 Adrianian StreetGR - 115 25 Athens, Greece 11525 [208] 21. Methodological Guide Lines For Socio Cultural Studies on Issue Related to Blood Donation - Pan American Health Organisation. 22. Organisation & Management of Blood Transfusion Service. Policies and Plans - Dr Z S Bharucha, Department of Transfusion Medicine Tata Memorial Hospital. Mumbai, Maharashtra, India. 23. Education as a Toot For Blood Donor Motivation and RecruitmentAssociation of Voluntary Blood Donors, West Bengal 20A, Fordyce Lane, Kolkata - 700014, India. 24. Science of Blood. and Blood Donation and Transfusion -Association of Voluntary Blood Donor, West Bengal, 20A, Fordyce Lane. Kolkata 700014. India 25. Blood - Dougls Starr. Little Brown & Co (U. K.), Brettenham House Lancaster Place, London WC 2E 7 EN U. K. 26. The Gift Relationship - Richard M. Titmus Revised. (1997) The New Press New York, U. K. 27. Effective Motivation - Johan Adail, Rupa & Co., 15 Bankim Chatterjee Street, Kolkata - 700 073, India. 28. Developing Presentation Skills - Dr R L Bhatia, Wheeler Publishing, 23 L B Shastri Marg. Allahabad, U P - 211 001, India. 29. Motivating to Win - Richard Denny, Kogan Page India Pvt Ltd. 4325/3 Ansari Road, Daryagunj, New Delhi - 110 002. India. 30. Voluntary Action - D K Ohja, National Book Trust. India, A-5 Green Park, New Delhi -110 016, India. 31. Guide Lines for Appropriate use of Blood - National AIDS Control Organisation, Chandralok Building, 36 Janpath New Delhi - 110 001. 32. Guide Book on Blood Donor Motivation - Association of Voluntary Blood Donors, Tamil Nadu, 6 Cathedral Road, Chennai - 600 004, Tamil Nadu. 33. Chicago Address - Swami Vivekananda - Advaita Ashram, 6 Dehi Entally Road, Kolkata - 700 014. [209] F. Journals (English) 1. Transfusion Today: ISBT Journal Blood Bank Noord Netherlands P. O. Box 1191 9701 BD Groningen Netherlands 2. Gift of Blood: Association of Voluntary Blood Donors, West Bengal 20 A Fordyce Lane Kolkata - 700 014 India 3. Donor Recruitment International: IFRRCS Journal P. O. Box 372 CH 1211, Geneva Switzerland [210] INDIAN RED CROSS SOCIETY. (Constituted under Act XV of 1920) President: HIS EXCELLENCY THE VICEROY AND GOVERNOR-GENERAL OF INDIA, (BENGAL PROVINCIAL BRANCH) Blood Bank Committee. Chairman: ‘ Major General W. C. PATON K. H. P., I. M. S. ALL INDIA INSTITUTE OF HYGINE AND PUBLIC HEALTH. 110, Chittaranjan Avenue, CALCUTTA The 6th March, 1942 MEMORANDUM The war has necessitated the establishment of Blood Banks at various centres in this country to meet war needs. The Imperial Serologist started a transfusion service in 1925 fur Calcutta in the School of Tropical Medicine, which resulted in the establishment of the present Blood Bank Committee in I939. This Committee was expanded for war-time needs and began present operations in January 1942. The Blood Bank has drawn up its “routines” for self-guidance and appraisal in the light of experience gained so far. These “routines” are naturally subject to modification with further experience. However, the accompanying is made public in case the procedures may be of some use to any other Banks now in course of establishment. It is universal experience that the actual procedures in any individual Bank must depend on local circumstances and experience gained locally. The Blood Bank at Calcutta will, so far as practicable, be prepared to furnish any further information upon request and will also be glad to render any assistance possible. W. C. PATON, MAJOR GENERAL, I.M.S. Surgeon-General with the Government of Bengal and Chairman, Blood Bank Committee. [211] Annexure I National Blood Policy INTRODUCTION: A well organised Blood Transfusion Service (BTS) is a vital component of any health care delivery system. An integrated strategy for Blood Safety is required for elimination of transfusion transmitted infections and for provision of safe and adequate blood transfusion services to the people. The main component of an integrated strategy include collection of blood only from voluntary, non-remunerated blood donors, screening for all transfusion transmitted infections and reduction of unnecessary transfusions. The Blood Transfusion Service in the country is highly decentralised and lacks many vital resources like manpower, adequate infrastructure and financial base. The main issue, which plagues blood banking system in he country, is fragmented management. The standards vary from State to State cities to cities and centre to centre in the same city. In spite of hospital based system, many large hospitals and nursing homes do not have their own blood banks and this has led to proliferation of stand-alone private blood banks. The blood component production/ availability and utilisation is extremely limited. There is shortage of trained health-care professionals in the field of transfusion medicine. For quality, safety and efficacy of blood and blood products, well-equipped blood centres with adequate infrastructure and I trained manpower is an essential requirement. For effective clinical use of blood, it is necessary to train clinical staff. To attain maximum safety, the requirements of good manufacturing practices and implementation of quality system moving towards total quality management, have posed a challenge to the organisation and management of blood transfusion service. Thus, a need for modification and change in the blood transfusion service has necessitated formulation of a National Blood Policy and development of a National Blood Programme which will also ensure Implementation of the directives of Supreme Court of India -1996. MISSION STATEMENT The policy aims to ensure easily accessible and adequate supply of safe [212] and quality blood and blood components collected / procured from a voluntary non-remunerated regular blood donor in well equipped premises, which is free from transfusion transmitted infections, and is stored and transported under optimum conditions. Transfusion under supervision of trained personnel for all who need it irrespective of their economic or social status through comprehensive, efficient and a total quality management approach will be ensured under the policy. OBJECTIVES OF THE POLICY To achieve the above aim, the following objectives are drawn: 1. To reiterate firmly the Govt. commitment to provide safe and adequate quantity of blood, blood components and blood products. 2. To make available adequate resources to develop and re-organise the blood transfusion services in the entire country. 3. To make latest technology available for operating the blood transfusion services and ensure its functioning in an updated manner. 4. To launch extensive awareness programmes for donor information, education, motivation, recruitment and retention in order to ensure adequate availability of safe blood. 5. To encourage appropriate clinical use of blood and blood products. 6. To strengthen the manpower through human resource development. 7. To encourage Research & Development in the field of Transfusion Medicine and related technology. 8. To take adequate regulatory and legislative steps for monitoring and evaluation of blood transfusion services and to take steps to eliminate profiteering in blood banks. OBJECTIVE - 1: To reiterate firmly the Govt. commitment to provide safe and adequate quantity of blood, blood components and blood products. [213] STRATEGY: 1.1. A national blood transfusion Programme shall be developed to ensure establishment of non-profit integrated National and State Blood Transfusion Services in the country. 1.1.1 National Blood Transfusion Council (NBTC) shall be the policy formulating apex body in relation to all matters pertaining to operation of blood centres. National AIDS Control Organisation (NACO) shall allocate a budget to NBTC for strengthening Blood Transfusion Service. 1.1.2 State/UT Blood Transfusion Councils shall be responsible for implementation of the Blood Programme at State/UT level, as per the recommendations of the National Blood Transfusion Council. 1.1.3 Mechanisms for better co-ordination between NBTC and SBTCs shall be developed by the NBTC. 1.1.4 Mechanisms shall be developed to monitor and periodically evaluate the implementation of the National Blood Programme in the country. 1.1.5 The enforcement of the blood and blood products standards shall be the responsibility of Drugs Controller General (India) as per Drugs and Cosmetics Act/Rules, with assistance from identified experts. 1.1.6 NBTC shall ensure involvement of other Ministries and other health programmes for various activities related to Blood transfusion services. 1.2. Trading in blood i. e. Sale & purchase of blood shall be prohibited. 1.2.1 The practice of replacement donors shall be gradually phased out in a time bound programme to achieve 100% voluntary non-remunerated blood donation programme. 1.2.2 State/UT Blood Transfusion Councils shall develop an action plan to ensure phasing out of replacement donors. 1.3 The following chain of Transfusion Services shall be promoted for making available of safe blood to the people. 1.3.1 State Blood Transfusion Councils shall organise the blood transfusion [214] service through the network of Regional Blood Centres and Satellite Centres and other Government, Indian Red Cross Society & NGO run blood centres and monitor their functioning. All Regional Centres shall be assigned an area around in which the other blood banks and hospitals which are linked to the regional centre will be assisted for any requirement and shall be audited by the Regional Centre. It will also help the State Blood Transfusion Council in collecting the data from this region. 1.3.2 The Regional Centres shall be autonomous for their day to day functioning and shall be guided by recommendations of the State/UT Blood Transfusion Councils. The Regional Centre shall act as a referral centre for the region assigned to it. 1.3.3 NBTC shall develop the guidelines to define NGO run blood centres so as to avoid profiteering in blood banking. 1.4 Due to the special requirement of Armed Forces in remote border areas, necessary amendments shall be made in the Drugs & Cosmetics Act/Rules to provide special licences to small garrison units. These units shall also be responsible for the civilian blood needs of the region. OBJECTIVE - 2: To make available adequate resources to develop and re-organise the blood transfusion service in the entire country. STRATEGY: 2.1 National & State/UT Blood Transfusion Councils shall be supported/ strengthened financially by pooling resources from various existing programmes and if possible by raising funds from international / bilateral agencies. 2.2 Efforts shall be directed to make the blood transfusion service viable through non-profit recovery system. 2.2.1. National Blood Transfusion Council shall provide guidelines for ensuring non-profit cost recovery as well as subsidised system. 2.2.2. Efforts shall be made to raise funds for the blood transfusion service for making it self-sufficient. [215] 2.2.3. The mechanism shall be introduced in government sector to route the amounts received through cost recovery of blood/blood components to the blood banks for improving their services. OBJECTIVE - 3: To make latest technology available for operating the blood transfusion services and ensure its functioning in an updated manner. STRATEGY: 3.1 Minimum standards for testing, processing and storage shall be set and ensured. 3.1.1. Standards, Drugs & Cosmetics Act/Rules and Indian Pharmacopoeia shall be updated as and when necessary. 3.1.2. All mandatory tests as laid down under provisions of Drugs & Cosmetics Act/Rules shall be enforced. 3.1.3. Inspectorate of Drugs Controller of India and State FDA shall be strengthened to ensure effective monitoring. 3.1.4. A vigilance cell shall be created under Central/State Licensing Authorities. 3.2 A Quality System Scheme shall be introduced in all blood centres. 3.2.1 Quality Assurance Manager shall be designated at each Regional Blood Centre/ any blood centre collecting more than 15,000 units per year to ensure quality control of Blood & its components in the region assigned. He shall be exclusively responsible for quality assurance only. 3.2.2 Every blood centre shall introduce an internal audit system to be followed by corrective actions to reduce variations in Standard Operating Procedures(SOPs) as a part of continuous improvement programme. 3.2.3 Regular workshops on the subject of quality assurance shall be conducted to update the personnel working in blood centres. 3.2.4 Regular proficiency testing of personnel shall be introduced in all the blood centres. [216] 3.3 An External Quality Assessment Scheme (EQAS) through the referral laboratories approved by the National Blood Transfusion Council shall be introduced to assist participating centres in achieving higher standards and uniformity. 3.3.l Reference centres shall be identified in each State/UT for implementation of EQAS. All blood centres shall be linked to these reference centres for EQAS. 3.3.2 NBTC shall identify a centre of national repute for quality control of indigenous as well as imported consumables, reagents and plasma products. 3.4 Efforts shall be made towards indigenisation of kits, equipment and consumables used in blood banks. 3.5 Use of automation shall be encouraged to manage higher workload with increased efficiency. 3.6 A mechanism for transfer of technology shall be developed to ensure the availability of state-of-the-art technology from out side India. 3.7 Each blood centre shall develop its own Standard Operating Procedures on various aspects of Blood Banking. 3.7.1 Generic Standard Operating Procedures shall be developed by the National Blood Transfusion Council as guidelines for the blood centres. 3.8 All blood centres shall adhere to bio-safety guidelines as provided in the Ministry of Health & Family Welfare manual "Hospital-acquired Infections: Guidelines for Control" and disposal of bio-hazardous waste as per the provisions of the existing Biomedical Wastes (Management & Handling) Rules- 1996 under the Environmental Protection Act -1986. OBJECTIVE - 4: To launch extensive awareness programmes for blood banking services including donor motivation, so as to ensure adequate availability of safe blood. [217] STRATEGY: 4.1 Efforts shall be directed towards recruitment and retention of voluntary, non-remunerated blood donors through education and awareness programmes. 4.1.1 There shall not be any coercion in enrolling replacement blood donors. 4.1.2 The replacement donors shall be encouraged to become regular voluntary blood donors. 4.1.3 Activities of NGOs shall be encouraged to increase awareness about blood donation amongst masses. 4.1.4. All blood banks shall have donor recruitment officer/ donor organiser. 4.1.5. Each blood centre shall create and update a blood donor's directory which shall be kept confidential. 4.1.6. In order to increase the donor base specific IEC campaigns shall be launched to involve youth in blood donation activities. 4.2. Enrolment of safe donors shall be ensured. 4.2.1 Rigid adherence to donor screening guidelines shall be enforced. 4.2.2 At blood donation camps, appropriate attention shall be paid on donor enrolment and screening in accordance with national standards instead of number of units collected. 4.2.3 A Counselor in each blood centre shall be appointed for pre and post donation counseling. 4.2.4 Result seeking donors shall be referred to a Blood Testing Centre (BTC) for post donation information and counseling. 4.3 State/UT Blood Transfusion Councils shall recognise the services of regular voluntary non-remunerated blood donors and donor organisers appropriately. 4.4 National/State/UT Blood Transfusion Councils shall develop and launch [218] an IEC campaign using all channels of communication including mass-media for promotion of voluntary blood donation and generation of awareness regarding dangers of blood from paid donors and procurement of blood from unauthorised blood banks/ laboratories. 4.5 National State/UT blood transfusion councils shall involve other departments/ sectors for promoting voluntary blood donations. OBJECTIVE: 5: To encourage appropriate clinical use of blood and hood products. STRATEGY: 5.1 Blood shall be used only when necessary. Blood and blood products shall be transfused only to treat conditions leading to significant morbidity and mortality that cannot be prevented or treated effectively by other means. 5.2 National Guidelines on "Clinical use of Blood" shall be made available and updated as required from time to time. 5.3 Effective and efficient clinical use of blood shall be promoted in accordance with guidelines. 5.3.1 State/UT Governments shall ensure that the Hospital Transfusion Committees are established in all hospitals to guide monitor and audit clinical use of blood. 5.3.2 Wherever appropriate, use of plasma expandes shall be promoted to minimise the use of blood. 5.3.3 Alternative strategies to minimise the need for transfusion shall be promoted. 5.4 Education and training in effective clinical use of blood shall be organised. 5.4.1 Medical Council of India shall be requested to take following initiatives: 5.4.1.1 To introduce Transfusion Medicine as a subject at undergraduate and all post graduate medical courses. [219] 5.4.1.2 To introduce posting for at least 15 days in the department of transfusion medicine during internship. 5.4.1.3 To include Transfusion Medicine as one of the subjects in calculating credit hours for the renewal of medical registration by Medical Council of India, if it is introduced. 5.4.2 CME and workshops shall be organised by State Blood Transfusion Councils in collaboration with professional bodies at regular intervals for all clinicians working in private as well public sector in their States. 5.5 Blood and its components shall be prescribed only by a medical practitioner registered as per the provisions of Medical Council Act - 956. 5.6 Availability of blood components shall be ensured through the network of regional centres, satellite centres and other blood centres by creating adequate number of blood component separation units. 5.7 Appropriate steps shall be taken to increase the availability of plasma fractions as per the need of the country through expanding the capacity of existing centre and establishing new centres in the country. 5.8 Adequate facilities for transporting blood and blood products including proper cold-chain maintenance shall be made available to ensure appropriate management of blood supply. 5.9 Guidelines for management of blood supply during natural and man made disasters shall be made available. OBJECTIVE: 6: To strengthen the manpower through Human Resource Development. STRATEGY: 6.1 Transfusion Medicine shall be treated as a speciality. 6.1.1 A separate Department of Transfusion Medicine shall be established in Medical Colleges. 6.1.2 Medical Colleges/Universities in all States shall be encouraged to start [220] PGdegree (MD in transfusion medicine) and diploma courses in Transfusion Medicine. 6.1.3 PG courses for technical training in transfusion medicine (PhD / MSc) shall also be encouraged. 6.2 In all the existing courses for nurses, technicians and pharmacists, Transfusion Medicine shall be incorporated as one of the subjects. 6.3 In-service training programmes shall be organised for all categories of personnel working in blood centres as well as drug inspectors and other officers from regulatory agencies. 6.4 Appropriate modules for training of Donor Organisers/ Donor Recruitment Officers shall be developed to facilitate regular and uniform training programmes to be conducted in all States. 6.4.1 Persons appointed as Donor Organisers/Donor Recruitment Officers shall undergo training for Donor Motivation and Recruitment organised by State Blood Transfusion Councils. 6.5 Short orientation training cum advocacy programmes on donor motivation and recruitment shall be organised for Community Based Organisations (CBOs)/NGOs who wish to participate in Voluntary Blood Donor Recruitment Programme. 6.6 Inter-country and intra-country exchange for training and experience of personnel associated with blood centres shall be encouraged to improve quality of Blood Transfusion Service. 6.7 States/UTs shall create a separate cadre and opportunities for promotions for suitably trained medical and para medical personnel working in blood transfusion services. OBJECTIVE: 7: To encourage Research & Development in the field of Transfusion Medicine and related technology. [221] STRATEGY: 7.1 A corpus of funds shall be made available to NBTC/SBTCs to facilitate research in transfusion medicine and technology related to blood banking. 7.2 A technical resource core group at national level shall be created to coordinate research and development in the country. This group shall be responsible for recommending implementation of new technologies and procedures in coordination with DC(I). 7.3 Multi-centric research initiatives on issues related to Blood Transfusion shall be encouraged. 7.4 To take appropriate decisions and/ or introduction of policy initiatives on the basis of factual information, operational research on various aspects such as various aspects of Transfusion Transmissible Diseases, Knowledge, Attitude and Practices (KAP) among donors, clinical use of blood, need assessment etc shall be promoted. 7.5 Computer based information and management systems shall be developed which can be used by all the centres regularly to facilitate networking. OBJECTIVE: 8: To take adequate legislative and educational steps to eliminate profiteering in blood banks. STRATEGY: 8.1 For grant/ renewal of blood bank licenses including plan of a blood bank, a committee, comprising of members from State/UT Blood Transfusion Councils including Transfusion Medicine expert, Central & State/UT FDAs shall be constituted which will scrutinise all applications as per the guidelines provided by Drugs Controller General (India). 8.2 Fresh licenses to stand-alone blood banks in private sector shall not be granted. Renewal of such blood banks shall be subjected to thorough scrutiny and shall not be renewed in case of non-compliance of any condition of licence. [222] 8.3 All State/UT Blood Transfusion Councils shall develop a State Action plan for the State/UT Blood Transfusion Service where in Regional Blood Transfusion Centres shall be identified. These centres shall be from Government, Indian Red Cross Society or other NGO run blood banks of repute. Approved regional blood centres/ government blood centres/Indian red cross blood centres shall be permitted to supply blood and blood products to satellite centres which are approved by the committee as described in para 8.1. The Regional Centre shall be responsible for transportation, storage, cross-matching and distribution of blood and blood products through satellite centres. 8.4 A separate blood bank cell shall be created under a senior officer not below the rank of DDC(I) in the office of the DC(I) at the headquarter. State/UT Drugs Control Department shall create such similar cells with the trained officers including inspectors for proper inspection and enforcement. 8.5 As a deterrent to paid blood donors who operate in the disguise of replacement donors, institutions who prescribe blood for transfusion shall be made responsible for procurement of blood for their patients through their affiliation with licensed blood centres. 8.6 States/UTs shall enact rules for registration of nursing homes wherein provisions for affiliation with a licensed blood bank for procurement of blood for their patients shall be incorporated. 8.7 The existing provisions of Drugs & Cosmetics Rules will be periodically reviewed to introduce stringent penalties for unauthorised/irregular practices in blood banking system. [Released by the Ministry of Health and Family Welfare, National AIDS Control Organisation, Government of India in April 6, 2002. Action Plan was released in May 2003. ] [223] Reading Materials for Donor Motivators [224] Annexure II National Blood Transfusion Council In accordance with the directive of the Supreme Court, National Blood Transfusion Council was constituted in 1996 as a Registered Society with its office at New Delhi with the objectives to: • • • • Promote voluntary blood donation Ensure safe blood transfusion Provide infrastructure to blood centres Develop human resource. The Council has its elaborate Memorandum of Association and Rules and Regulation. Additional Secretary and Project Director, National AIDS Control Organisation, Ministry of Health and Family Welfare. Govt, of India, is the President of the Council and the Director National Council who shall be appointed by the Governing Body with the prior approval of the Union Government shall be the Member Secretary. The Governing Body can have not more than fourteen members at present but the first Governing Body however was constituted with seven members. The management of the affairs of the Council shall be entrusted to the Governing Body. The Governing Body shall have the power to constitute the Executive Committee as hereunder: 1. President of the Council Member 2. Representatives from the Directorate General of Member Health Services. Govt, of India Member 3. Representatives of the Ministry of Finance Govt. of India 4. Drugs Controller of India Member 5. One expert in Blood Transfusion Medicine Member 6. Representative from Indian Red Cross Society Member 7. Director, National Council Member, Secretary [225] Annexure III State Blood Transfusion Council In 1996, State Blood Transfusion Council in all states and union territories were formed. This was according to the directive of the Supreme Court The main objectives of the State Council are to: • • • • Promote voluntary blood donation through education Ensure appropriate use of blood Develop nodal centres/district and subdivision blood centres. Initiate human resource development programme. The Governing body of the State Council to whom the management of its affairs is entrusted shall be constituted in the following manner: President 1. Secretary to the Department of Ministry of Health & Family Welfare Member 2. Director of Health Services Member 3. State Drugs Controller Member 4 Representative of Ministry of Finance 5. 6. Representative of State Red Cross Society Member Representative of Private Blood Banks 7&8. Maximum two experts in Blood, Transfusion Medicine & Health Institution of the State 9. Representative of Non-Government Organisation (active in the field) Member Member 10. Representative of Nodal Blood Centres 11. Director, State Council Member Member Member, Secretary The State Councils are to be funded by Union and State Government. National AIDS Control Organisation. State Blood Transfusion Councils have power to collect donations. All donations to the Councils are 100% income tax free. [226] Annexure IV Drug Rules Relevant Portions of Drugs and Cosmetics Rules (1999) for blood donor motivators are reproduced: This amended Drugs and Cosmetic rules are applicable for Blood Banks and Blood Donations effective in the country from April 5, 1999. Some Definition: "Donor" means a person who voluntarily donates blood after he has been declared fit after a medical examination, for donating blood, on fulfilling the criteria given herein after, without accepting in return any consideration in cash or kind from any source, but does not include a professional or paid donor. Explanation: For the purpose of this clause, benefits or incentives like pins, plaques, badges, medals, commendation certificates, time off from work, membership of blood assurance programme, gifts of little intrinsic or monetary value shall not be construed as consideration. "Professional donor" means a person who donates blood for a valuable consideration, in cash or kind, from any source, on behalf of the recipient - patient and includes a paid donor or a commercial donor. "Replacement donor" means a donor who is a family friend or a relative of the patient recipient. License; Each Blood Bank must have licence from Central Licence Approving. Authority of Ministry Health and Family Welfare on the basis of recommendation of Director, Drug Control of the State. Conditions of Licence 1. The licensee shall neither collect blood from any professional donor or paid donor nor shall he prepare blood components from the blood collected from such a donor. 2. The licence and any certificate of renewal in force shall be displayed on the approved premises and the original shall be produced at the request of an inspector appointed under the Drugs and Cosmetics Act, 1940. [227] 3. The licensee shall inform the Licensing Authority and/or Central Licence Approving Authority in writing in the event of any change in the constitution of the firm operating under the licence. Where any change in the constitution of the firm takes place the current licence shall be deemed to be valid for maximum period of three months from the date on which the change has taken place unless in the meantime, a fresh licence has been taken from the Licensing Authority and /or Central Licence Approving Authority in the name of the firm with the changed constitution". Requirements for the Functioning and Operation of a Blood Bank and/or Preparation of Blood Components: A. General: 1. Location and Surroundings: The blood bank shall be located at a | place which shall be away from open sewage, drain, public lavatory or similar unhygienic surroundings. 2. Building: The building(s) used for operation of a blood bank and/ or preparation of blood components shall be constructed in such a manner so as to permit the operation of the blood bank and preparation of blood components under hygienic conditions and shall avoid the entry of insects, rodents and flies. It shall be well lighted, ventilated and screened (mesh), where necessary. The walls and floors of the rooms, where collection of blood or preparation of blood components or blood products is carried out shall be smooth, washable and capable of being kept clean. Drains shall be of adequate size and where connected directly to a sewer shall be equipped with traps to prevent back siphonage. 3. Health, clothing and sanitation of staff: The employees shall be free from contigious or infectious diseases. They shall be provided with clean overalls, head-gears, foot-wears and gloves, wherever required. There shall be adequate, clean and convenient hand washing and toilet facilities. Accommodation for a Blood Bank: A blood bank shall have an area of 100 square meters for its operations and an additional area of 50 square meters for preparation of blood components. It shall be consisting of a room each for (1) registration and medical examination with adequate furniture and facilities for registration and selection of donors. [228] (2) blood collection (air-conditioned) (3) blood component preparation (This shall be air-conditioned to maintain temperature between 20 degree centigrade to 25 degree centigrade). (4) laboratory for blood group serology (air-conditioned). (5) laboratory for blood transmissible diseases like Hepatitis. Syphilis. Malaria. HIV-antibodies (air-conditioned) (6) sterilization-cum-washing. (7) refreshment -cum-rest room (air-conditioned) (8) store -cum-records Notes: (1) The above requirements as to accommodation andarea may be relaxed, in respect of testing laboratories and sterilizationcum-washing room, for reasons to be recorded limiting by Licensing Authority and/or the Central Licence Approving Authority, in respect of blood banks operating in hospitals. provided the hospital concerned has pathological laboratory and a sterilization-cum-washing room common with other departments in the said hospital. (2) Refreshments to the donor after phlebotomy shall be served so that he is kept under the observation in the Blood Bank. Personnel Every blood bank shall have following categories of whole time competent technical staff and their number shall be in accordance with the quantum of work load: (a) Medical Officer - With a Degree in Medicine (M. B. B. S. ) of a University recognised by the Central Government and having experience in a Blood Bank for one year during regular service. He shall have adequate knowledge and experience in Blood Group Serology, Blood Group Methodology and Medical principles involved in procurement of blood/ or preparation of its components. (b) Technical Supervisor - with a Degree in Medical Laboratory Technology (M L T) or equivalent qualifications with one year experience in the processing and preparation of blood components. [229] (c) Registered Nurse(s). (d) Blood Bank Technician(s) - With a Degree in Science subject and having a certificate/ Diploma in M. L. T. (Diploma in Medical Laboratory Technology) as recognised by a State Government/ Union Territory, with one year of experience. NOTE: (a) The number of whole time technical personnel required by a blood bank shall be such as may be approved by the Licensing Authority or Central Licence Approving Authority, in accordance with the quantum of workload in a blood bank. (b) It shall be the responsibility of the licensee to demonstrate through maintenance of records and other latest techniques used in blood banking system and the personnel involved in blood banking activities for collection, storage, testing and distribution are adequately trained in the current Good Manufacturing Practices/ Standard Operating Procedures for the tasks undertaken by each personnel. The personnel shall be made aware of the principles of Good Manufacturing Practices/ Standard Operating Procedures that affect them and receive initial and continuing training relevant to their needs. Criteria for Blood Donation Condition for donation of blood (1) General: No person shall donate blood and no blood bank shall draw blood from a person, more than once in three months. The donor shall be in good health, mentally alert and physically fit and shall not be inmates of jail, persons having multiple sex partners and drug-addicts. The donors shall fulfil the following requirements, namely: (a) the donor shall be in the age group of 18 to 60 years; (b) the donor shall not be less than 45 kilograms; (c) temperature and pulse of the donor shall be normal; (d) the systolic and diastolic blood pressure are within normal limits without medication; (e) haemoglobin which shall not be less than 12. 5 gms/hundred ml. [230] (f) the donor shall be free from acute respiratory disease; (g) the donor shall be free from any skin diseases at the site of phlebotomy; (h) the donor shall be free from any disease transmissible by blood transfusion, in so far as can be determined by history and examination indicated above; (i) the arms and forearms of the donor shall be free from skin puncture or scar indicative of professional blood donors or addiction of self injected narcotics. 2. Additional qualification of a donor: No person shall donate blood, and no blood bank shall draw blood from a donor, in the conditions mentioned in column (1) of the Table given below before the expiry of the period of deferment mentioned in the column (2) of the said Table: Table: Deferment of blood donation PERIOD OF DEFERMENT CONDITIONS (2) (a) (1) Abortions 6 months (b) History of blood transfusion 6 months (c) Surgery 12 months (d) Typhoid 12 months after recovery (e) History of Malaria and duly treated 3 months (endemic) 3 years (non endemic area) (f) Tattoo 6 months (h) Breast feeding 12 months after delivery (i) Immunization (Cholera) Typhoid, Diptheria, Tetanus. Plague, Gammaglobulin) 15 days (j) Rabies vaccination 1 year after vaccination (k) History of Hepatitis in family or close contact 12 months (l) Immunoglobulin 12 months [231] (3) No person shall donate blood and no blood bank shall draw blood from a person, suffering from any diseases mentioned below: b) Heart disease a) c) Cancer Abnormal bleeding tendencies d) Unexplained weight loss e) Diabetes controlled on insulin f) Hepatitis B infection g) Chronic nephritis h) Signs and symptoms, suggestive of AIDS i) Liver disease j) Tuberculosis k) Polycythemia Vera l) Asthma m) Epilepsy n) Leprosy o) Schizophrenia P) Endocrine disorders General Equipment and Instruments: 1. For blood collection room: (i) Donor beds, chairs and tables: These shall be suitable and comfortably cushioned and shall be of appropriate size. (ii) Bedside table (iii) Sphygmomanometer and Stethoscope (iv) Recovery beds for donors (v) Refrigerators for storing separately tested and untested blood maintaining temperature between 2 and 6 degree centigrade with digital dial thermometer recording thermograph and alarm device. with provision for continuous power supply. (vi) Weighing devices for donor and blood containers. 2. For haemoglobin determination: (i) Copper sulphate solution (specific gravity 1. 053) (ii) Sterile lancet and impregnated alcohol swabs (iii) Capillary tube (1. 3x1. 4x96 mm or pasteur pipettes) (iv) Rubber bulbs for capillary tubings (v) Sahli's haernoglobinometer/Colorimeteric method [232] 3. For temperature and pulse determination: (i) Clinical thermometers (ii) Watch (fitted with a seconds-hand) and a stop watch. 4. For Blood containers: (a) Only disposable PVC blood bags shall be used (closed system) as per the specifications of IP/USP/BP. (b) Anti-coagulants: The anti-coagulant solution shall be sterile, pyrogenfree and of the following composition that will ensure satisfactory safety and efficacy of the whole blood and/or for all the separated blood components. (c) Citrate Phosphate Dextrose Adenine solution (CPDA) or Citrate Phosphate Dextrose Adenine 1 (CPDA1) - 14 ml solution shall be required for 100 ml of blood. NOTE 1 (i) In case of single/double/triple/quadruple blood collection bags used for blood component preparations, CPDA blood collection bags may be used. (ii) Acid Citrate Dextrose solution (ACD with Formula-A) I. P. 15 ml solution shall be required for 100 ml of blood. (iii) Additive solutions such as SAGM, ADSOL, NUTRICEL may be used for storing and retaining Red Blood Corpuscles upto 42. days. 5. Emergency equipments/items: (i) Oxygen cylinder with mask, gauge and pressure regulator; (ii) 5 percent Glucose or Normal Saline; (iii) Disposable sterile syringes and needles of various sizes; (iv) Disposable sterile I. V Infusion sets; (v) Ampoules of Betamethasone injections; Adrenaline, Noradrenaline, Mephentin, or Dexamethasone, Metoclorpropanide (vi) Aspirin and spirit Ammonia Aromatic. [233] 6. Accessories: (i) Such as blankets, emesis basins, haemostats, set clamps, sponge forceps, gauze, dressing jars, solution jars, waste cans, (ii) Medium cotton balls, 1. 25 cm adhesive tapes. (iii) Denatured spirit. Tincture Iodine, green soap or liquid soap. (iv) Paper napkins or towels (v) Autoclave with temperature and pressure indicator (vi) Incinerator (vii) Standby generator. TESTING OF WHOLE BLOOD: Each blood unit shall also be tested for freedom from Hepatitis B surface antigen, VDRL and malerial parasite and HIV I and HIV II antibodies and results of such testing shall be recorded on the label of the container. NOTE: (a) Blood samples of donors in pilot tube and the blood samples of the recipient shall be preserved for 7 days after issue. (b) The blood intended for transfusion shall not be frozen at any stage. (c) Blood containers shall not come directly in contact with ice at any stage. RECORDS: The records which licensee is required to maintain shall include inter alia the following particulars: — Blood donor record: It shall indicate serial number, date of bleeding, name, address and signature of donor with other particulars of age, weight, hemoglobin, blood grouping, blood pressure, medical examination, bag number and patient's detail for whom donated in case of replacement donation category of donation (voluntary /replacement) and deferra records and signature of Medical Officer in-charge. [234] LA BEL S: The labels on every bag containing blood and/or component shall contain the following particulars, namely: (1) The proper name of the product in a prominent place and in bold letters on the bag. (2) Name and address of the blood bank (3) Licence number (4) Serial number (5) The date on which the blood is drawn and the date of expiry as prescribed under Schedule P to these rules: (6) A colored label shall be put on every bag containing blood. The following colour scheme for the said labels shall be used for different groups of blood. Blood Group Color of the label O Blue A Yellow B Pink AB White (7) The results of the tests for Hepatitis B surface antigen, syphilis freedom from HIV I, and HIV II antibodies and malaria parasite. (8) The Rh group (9) Total volume of bags, the preparation of blood, nature and percentage of anti-coagulant. (10) Keep continuously temperature at 2 degree centigrade to 6 degree centigrade. (11) Disposable transfusion sets with filter shall be used in administration equipment (12) Appropriate compatible cross matched blood without a typical antibody in recipients shall be used. [235] Annexure VII Training Modules for Blood Donor Motivators Module I: Orientation Workshop on Approach to Voluntary Blood Donation Target Group: Blood Bank personnel working in the field of blood donor motivation, blood collection, blood supply across counter i. e., having opportunity to meet face to face with donor, intending or prospective donor, patients’ relatives and friends in need of blood and blood donor organisers/ social workers/donor motivators/volunteers of other social welfare organisations in the field of blood donor recruitment. Object (i) To impress upon the participants that blood donor motivation is a art based on science and should be practised with dedication and organised manner. (ii) To expose a large number of people in the field to a organised structured training schedule as a crash programme. Entry Behaviour: Prior experience in the field of blood banking: or blood donor recruitment. Duration: 4 hours. Course Content Unit 1: Basic Concept Indications of blood transfusion in modern medical science; history of blood banking with special reference to India and the particular state or district where the programme would be offered: basic functions of blood bank; present system of blood banking and blood need of the state concerned; types of blood bank in the state, types of blood donors; evils of commercialisation of blood, need of a voluntary blood donor base in the region to ensure safe blood transfusion; role of blood donor motivators and organisers to recruit and retain voluntary blood donors to achieve total voluntary blood programme. Unit 2: Basic Blood Science Elementary concept of blood circulation, vein and artery - nature of blood flowing through them. Blood component -cells-R. B. C., W. B. C, [248] platelets plasma; percentage composition of cells, liquid part and water. Blood volume (Male, Female), amount of donation, surplus; recuperative period, life span of cells, shelf life of blood. Blood group and importance of knowing one’s blood group; Donor screening - safety of donor and recipient. Blood communicable diseases and safe blood transfusion. Unit 3: Principles and Practice of Blood Donor Motivation and Recruitment Definition of motivation. Principles of blood donor recruitment Education, Motivation, Donation and Recognition. Target Setting. Identification of Target groups. Method of approach, short term and long term methods. Blood donation in camp and blood donation in blood bank, consent of donor; Panel donor - formation and utilisation. Anonymity between donor and recipient to meet fresh blood and rare group blood need. Unit 4: Communication and Public Relations Types of communication, Fundamental basic tools of Donor recruitment. Theory of oral communication, preparation for oral communication, maintaining time frame, preparation and use of posters, folders. Do’s and don’ts of public relations. Telephonic communication and handling people across the counter and handling of grievances and complaints. Feed back and reinforcement. Module II: For Blood Donor Motivators and Recruiters Object: (i) To introduce the social workers and donor organisers to the various facets of blood donor recruitment; (ii) To inspire the social workers and donor organisers to work with respect and dignity to achieve their target or reach the goal. (iii) To instil a sense of importance about the vital basic area of blood banking to ensure safe blood transfusion in the minds of social workers and donor organisers. Duration: 12 hours. [249] Course Content Unit 1: Broad Perspective Importance of blood banking and blood transfusion in modern medical science, history of blood banking, blood transfusion science and blood donation movement at home and abroad. Unit 2: Blood Bank Need of blood banks; types of blood banks in the country; functions of ideal blood banks; source of blood - voluntary blood donor, relative and replacement blood donor, blood sellers; evils of commercialisation of blood; ethics in blood banking, blood banking system of the concerned region; how to get blood at the time of need. Unit 3: Basic Blood Science Blood, its composition, function, types and functions of cells and plasma, percentage of cell, liquid portion and water content, life span of RBC. circulation system, venous and arterial blood, volume calculation, amount of surplus and amount of donation, recuperative power of human body; recuperation of cells and plasma is a natural process, no special diet or medicines required; pain one has to suffer at the time of donation. Unit 4: Blood Groups ABO and Rh systems, its meaning and significance in blood transfusion. Importance of knowing one’s own blood group; compatibility of blood group; concept of universal donor and recipient. Haemolytic disease of new born and precautions. Need of blood group tests in pregnancy and provision of blood in case of Rh negative mother. Unit 5: Precautions from Blood Communicable Diseases and Inherited Blood Diseases Blood communicable diseases - Hepatitis. STD, Malaria, AIDS; tests, validity, cost and time involved; quality of blood donor and education. Inherited blood diseases -Haemophilia and Thalassaemia; technique of meeting their blood need; counselling for the donors and patients. Unit 6: Blood Donor Screening Objectives of donor screening, safety of the donor and safety of the recipient, scientific donor screening helps in donor motivation. Principles, techniques and strategies of donor screening - history of past illness and present ailments, date of last blood donation, age, body weight. Physical [250] examination - heart, lung, liver, spleen, blood pressure, pulse, temperature and physical appearance. Haemoglobin estimation. National standard of blood donor screening. Role of social worker and doctors in donor screening. Temporary deferral and permanent deferral; technique of handling unfit intending blood donor. Need of uniformity of donor screening standard in all the blood banks of the country, education for self exclusion. Unit 7: Principles of Blood Donor Motivation Four basic principles of blood Donor recruitment -Education, Motivation. Donation and Recognition. Why people do not donate blood, why people donate blood, why people don’t donate blood after their first blood donation. Need for both recruiting new blood donors and retaining old blood donors to build up a healthy voluntary blood donor base to develop the culture of blood donation in the community: consent of donors. Types of approach - Individual or personal approach. Group approach and Mass approach. Need of short term and long term programmes. Unit 8: Donor Motivation Practice (Techniques) Dividing the community into target groups; determining the method of approach. Short term approach techniques for donor recruitment, advantage of blood donation in outdoor camps in the place of respective target groups; mass blood donation camps, identification of days of blood donation of the group on significant or auspicious day of that group; use of media - news paper, periodicals, TV and Radio. Designing and producing campaigning materials like - posters, folders, stickers, hoardings, newspaper ads. TV, Radio spots and programmes in different slots; preparation and use of audio visual aids-slides, audio and video cassettes, transparencies for overhead projectors. Techniques of honouring and recognising donors. Long term programme for the donors of tomorrow - school education programme - philosophy and technique, demonstration of blood donation camps in school. Unit 9: Blood Donation Camp Planning and setting up blood donation camp; Furniture, equipment, layout, physical facilities. Using blood donation camp as a tool of blood donor motivation. Cleanliness, discipline, consent, comfort, entertainment and handling of donors from reception to send off; paper work in blood donation camps, significance and simplification. Refreshment of donor budget. menu, serving; donors badge and certificate; donors card: after donation care; management of donor in case of post donation shock or any other inconvenience. Role of Social Worker in the camp. Liaison with technical people and their work. [251] Unit 10: Communication Techniques Types of communication, principles of oral communication, preparation of lecture/ lesson for short term and long term goal; principles and techniques of lecture planning, home work; voice, modulation of voice, pronunciation, pitch of the voice, audibility, study of mental make up of the audience, eye contact, mannerism, use of story, stories as a vehicle of communicator. selection and presentation of story, time planning -over stepping beyond allotted time. Use of audio visual aids and distribution of campaign materials and literature. Unit 11: Organisation The need for an organisation within or outside the blood bank for recruiting blood donors like blood donors society, club, association by involving the community - method of formation, registration, running office work and management of such organisations, books of account; meetings and meeting procedures and constitution, recruitment and training of volunteers. Unit 12: Social Worker and Donor Organisers Qualities of social workers, development of social workers, types of leadership qualities, innovative and imaginative leader, responsibilities of leader, self development, updating, information level. Project: (1) (2) (3) To visit a blood bank To visit an outdoor blood donation session To attend a donor motivation session. Module III: Refresher Course For Senior Motivators Object: To help the motivators to perform better. Duration: 15 hours. Course Content Unit 1: Land and people Population, area, districts, language, “festival, literacy, birth rate, death, rate, historical background, contribution to the culture of the country number of blood banks in the state, total requirement and collection from voluntary blood donors in the country, blood requirements of the state collection from other different sources. [252] Unit 2: Background Transfusion medicine is a speciality with blood donor motivation as its foundation, role of blood donor motivators and organisers. Historical background of blood banking from ancient days to work of Dr William Harvey, Dr. Richard Lower, Dr James Blundell, Dr Karl Landsteiner, Dr Hustin, Dr Andre Bagdasorov, Dr Norman Bethune, advancement during the second world war, Korean war and Vietnam war. Growth and development of blood transfusion service in India- vis-a-vis the voluntary blood donation movement in different states and union territories. Unit 3: Basic Blood Science What is blood; composition of blood - blood cells and plasma -their percentage composition; cells, plasma and water in plasma, types of blood ceils - RBC. WBC, platelets - function and life span, automatic destruction and replacement of cells; blood circulation system, function of heart and lungs; significance of blood pressure, venous blood and arterial blood; reason for blood collection from vein: approximate distance travelled by a blood cell and approximate volume of blood pumped by heart in a day in a circulation system; blood volume, meaning of total volume, approximate volume of blood per unit Kg body weight for male and female; amount required in the circulation system for routine work, amount of surplus, storage places of surplus blood- liver, spleen, lungs; amount of donation its scientific basis, minimum body weight required for donating blood, normal recuperative power of human body; no special diet or medicine is required, amount of blood donation and interval between each donation, recuperative power of human body, shelf and of blood, modern improvement in blood preservation. Unit 4: Blood Group Discovery of Blood Groups, ABO system of Blood Groups, significance and importance of ABO and Rh system of blood group in blood transfusion; who can receive blood from whom; statistics of percentage of people belonging to different blood group in the world, country and the region, inheritance of blood group - it does not change in life, method of determining blood group in laboratory; compatibility test and cross matching; advantage and importance of knowing one’s own blood group, meaning of rare group, easiest way to know one’s own blood group is by donating blood voluntarily. [253] Unit 5: Blood Donor Screening for Safe Blood Transfusion Meaning and object of donor screening, safety of donor, safety of recipient, quality of blood; need of safe blood transfusion; scientific donor screening is a part of donor motivation strategies; temporary unfit willing donor- responsibility and behaviour pattern of social worker and donor organisers in each case. History of past ailments, last date of donation, time of last meal taken, body weight, age. physical check up - heart, liver, spleen, pulse, temperature by medical officer of the camp, estimation of haemoglobin, role of social workers, decision of medical officer present in the camp is final. Tests undertaken in the blood bank, need of uniform standard for donor screening in all blood banks. National guideline. Self exclusion. Unit 6: Human Psychology Basic human need, analysing human psychology in blood donor recruitment. Psychology of donor, non-donor and one time donor, common apprehension of people on blood donation. Donor has a right to know. Common expectation of donors. Necessity of designing donor recruitment programme on the basis of above psychology and need. Unit 7: Blood Bank Need of blood bank; types of blood banks in the country; functions of ideal blood banks; procurement of blood by blood banks from voluntary donors in camps or bank and replacement or relative or directed donor evils of commercialisation of blood; ethics in blood banking. Blood Banking system of the concerned state; how to get blood in time of need, panel donor, on call donor system. Unit 8: Principles of Blood Donor Motivation Four basic principles of Blood Donor Recruitment - Education, Motivation, Donation and Recognition; why people do not donate blood, why people donate blood, why people do not donate blood after their first blood donation. Need of both recruiting new blood donor and retaining old blood donor base to develop the culture of blood donation in the community; consent of donors. Types of approach - Individual or personal approach, Group approach and Mass approach. Need of short term and long term programmes. Unit 9: Donor Motivation Techniques Dividing the community into target groups; determining the method of approach. Short term approach techniques for donor recruitment, advantage of blood donation in outdoor camps in the place of respective [254] target group; mass blood donation camps, identification of days of blood donation of the group: use of media - news paper, periodicals, TV & Radio. Designing and producing campaign materials like - posters, folders, stickers, hoardings, news paper ads, TV, Radio Spots and programmes in different slots: preparation and use of Audio Visual aids - slides, audio and video cassettes, transparencies for overhead projectors. Techniques of honouring and recognising donors. Long term programme for the donors of tomorrow. Unit 10: Blood Donation Camp Planning and setting up blood donation camp; Furniture, equipment, layout, physical facilities. Using blood donation camp as a tool of blood donor motivation. Adantage of blood collection in camp over collection in blood bank or mobile van. Cleanliness, discipline, consent, comfort, entertainment and handling of donors from reception to send off; paper work in donation camp - significance and simplification: Refreshment of donor- budget, menu, serving; donors badge and certificate; donors’ card; - after donation care; management of donor in case of post donation shock or any other inconvenience. Role of social worker in the camp. Liaison with technical people and their work. Unit 11: Communication Techniques Types of communication, principles of oral communication, preparation of lecture/ lesson for short term and long term goal; principles and techniques of lecture planning, home work; voice, modulation of voice, pronunciation, pitch of the voice, audibility, study of mental make up of the audience, eye contact, mannerism; use of correct fact, figures and statistics. Use of story, stories as a vehicle of communication, technique of story telling, time planning - over-stepping beyond allotted time. Use of Audio-visual aids and distribution of campaign materials and literature. Unit 12: Demand and Supply of Blood for Transfusion Indications of blood transfusion, - Major area. Source of supply; Techniques of estimating blood need of country/ state/ region /hospital. Planning to meet blood need. [To be worked out by using relevant data of a hospital or a region]. Blood donor per thousand of eligible population of developed, developing countries including India. Fresh blood need, blood need in disaster, blood need in blood diseases - Techniques of meeting these needs. Unit 13: Social Worker Definition of social work and social worker. Basic difference between a common person and a social worker, human need and want. Why people [255] should do social work. Qualities temperament, background of social worker Knowledge and information level of social workers in the role of blood donor motivator / organiser/ recruiter. Expectations from social worker to meet the challenge of blood donor recruitment to ensure safe blood transfusion and achieve total voluntary programme for his/ her area of work. Unit 14: Blood Communicable Diseases Malaria, Hepatitis. Syphilis, AIDS; available laboratory tests in he country - validity of tests, time required for each test and cost involved Theoretical knowledge about the name and method of each tests Demonstration of laboratory tests. Feedback of laboratory tests to the donor or donor organisers and the mode of communication. Confidentiality. Unit 15: School Education Programme Object of planning the recruitment of donors of tomorrow. Importance of school education programme in blood donation movement; Reasons for selecting school students for education on blood donation: Model; of school education programme used all over the world -Models used in Portugal, France, U. S. A.. Australia and India. Technology of the Indian programme, contents of the programme, methods of teaching aides to be used, stories as vehicles of communication. Do’s and Don’ts of school teaching faculty. Should this programme be undertaken as a part of school syllabus or as an extension lecture by social workers? Difference between mode of teaching in a school and a talk in a seminar. Children in the role of donor organiser and message carriers to elders. Demonstration blood donation camp or demonstration blood grouping camp in school. (Source: AVBDWB] [256] Documents on Blood Donor Motivation [257] Guidebooks of Blood Donor Recruitment [258] Annexure VIII Slogans on Blood Donation With appropriate visuals, posters and stickers may be prepared with these slogans. In hoardings and TV spots these slogans may also be used: 1. A bottle of blood saved my life. Was it yours? 2. My son is back home because you donated blood. 3. Ma is coming back home because you gave blood. 4. Blood donation is a friendly gesture. 5. Blood owners should be blood donors. 6. Blood is meant for circulation. Donate Blood. 7. Blood Donors bring Sunshine. 8. Keep blood bank shelves full. You may need blood someday. 9. Someone is needing blood somewhere. 10. Life of some patients is resting on a fraction of hope in quest of your gift of love. 11. A life in the surgeon’s hand may be yours. Donate blood for tomorrow. 12. Observe your birthday by donating blood. 13. Wouldn’t you have given blood if this child was yours? 14. Donate blood - Gift life. 15. Give mankind the greatest gift. Donate blood when Blood Bank comes to your place. 16. A few drops of your blood can help a life to bloom. 17. At 18 you grow up. At 18 you drive. At 18 you give blood to keep someone alive. 18. Give the gift that keeps on living. Donate blood. 19. We need you to save life. 20. You don’t have to have a medical degree to save a life. Just a fair degree of humanity. Give Blood. Save Life. 21. Blessed are the young who can donate blood. 22. Blood donation will cost you nothing but it will save a life ! 23. Patients need your gift of love to fight against mortal sickness. 24. Your donation of blood today may be an investment for your future. 25. Share blood - Share life. 26. It is a joy to give blood. 27. Tears of a mother cannot save her Child. But your blood can. 28. Be a blood donor and save a life. 29. Donation of blood means a few minutes to you but a lifetime for somebody else. [259] 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. People can get along without teeth or hair but not without blood. Donation of blood is harmless and safe. Safe blood starts with me. You can donate blood 168 times between the age of 18 - 60 years. Your refusal to donate blood may cost a life of your near and. dear one. A life is waiting for a bag of blood from you. Remember, today you can give your blood. Tomorrow your near and dear one may need it. Every tomorrow needs a blood donor today. Many things in this world can wait but transfusion of blood to a dying patient cannot. Calling blood donors to save life. Can you hear? Give a gift of love. Your own blood. Vote for life with your Blood. Be a Life Guard. Give Blood to save life. Have you donated Blood? If not — do it Now. Give the gift of Blood, the gift of life. For every 1000 who can donate blood only four do! What about you! Give Blood and gift a life. Blood is meant to circulate. Pass it around. If blood bank gives blood only to the blood donors, what would be the chance of those who depend on you? Five minutes of your time + 350 ml. of your blood = One life saved. I am a blood donor. Are you too ? The finest gesture one can make is to save life by donating blood. Blood donors bring a ray of hope. Blood for human comes from human beings only. Blood Bank cannot get blood from stone. Blood Donation would not hurt you, but it would save a life. Thank you. Blood Donor. Be a regular Blood Donor. Blood has no substitute as yet. Anybody having a heart to respond can donate blood to save life. Blood donation - a Gift of Love. Do not shed blood. Donate Blood. You can be a life saver without knowing swimming. Have a heart. Give Blood. [260] 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. 96. 97. 98. 99. 100. Donate blood so that others may live. Donation of blood makes a difference between life and death. It is time to roll up your sleeve to offer your gift of love. Share a little, care a little - Donate Blood. You too can have the joy of saving a man’s life by donating blood. Do you have a blood donor friend to stand by you in time of your need? You too can take up the job of saving a life by just donating your blood. Do you make friendship with blood donors? Let us be blood brothers. Let blood bind us together in friendship for ever. The colour of human blood is red all over the world. Anywhere you can donate your blood. It’s time to go to Blood Donation Camp. Donating blood is a social responsibility The blood is red gold in time of saving a life. Blessed are the young who can give back life with their blood — Donate blood, save a life. To the young and healthy it’s no loss. To sick it’s hope of life. Donate blood to give back life. Donate blood to save the dying. Care, share and live by donating blood. Among flowers — the Rose. Among Human beings — the blood donor. Life is precious. Save a life by donating a little bit of your blood. Blood donation is safe. It will cost you nothing but a few moments of your time. Heart beat goes on - when you give blood. Are you a blood donor? Blood is for the people by the blood donors. Help them. Help others, make your blood donation. You cannot manufacture blood in factory. It has to be donated by human being. Safe blood starts with voluntary blood donors. Light up a lamp of life by donating blood. Share the joy of life, give the life of a child by donating blood. I am proud, there is blood donor in my family. The blood donor of today may be recipient of tomorrow. Voluntary blood donors are the key to safe blood. [261] Many people pray for mountains to be moved when all they need is to climb. Donate blood for your near and dear one. Excuses never save a life. Blood donation does. Smile and give, some one will smile and live. Someone lives when someone gives. There is no substitute of human blood. The finest gesture one can make is to save life by donating blood. Drive carefully — otherwise you might need me — 1 am a blood donor. Share the happiness of glory. There is a feeling of joy when you give the gift of blood. [262] Annexure IX Important Dates for Blood Donation Drives It has been observed that different organisations or groups love to organise their blood collection drive on a significant day. The day may have international, national, regional and local significance. The donor motivators have to be on the lookout for such days and make them popular for blood collection drives. In India nobody observed Independence Day by donating blood before 1964. Now throughout the country on this day hundreds of blood donation drives are organised. A calendar can be prepared with a little bit of library work and by using encyclopaedia of dates and events, so that every day can be a significant day for blood donation for some group or the other. The days of joys and sorrows, anniversaries, historical events, may be the days of blood donations. Some examples are shown below: January 1 12 14 15 23 26 27 30 February 3 11 19 21 22 28 March 8 12 15 16 18 19 20 Birthday of Guru Gobinda Birthday of Swami Vivekananda & National Youth Day. Birthday of Martin Luther King & Albert Schweitzer Army Day Birthday of Netaji Subhas Chandra Bose Republic Day World Leprosy Day Martyrs’ Day Frank Worrell Day World Day of Sick Birthday of Shivaji Bhasa Sahid Dibash International Girls’ Guide Day Science Day International Women’s Day National Volunteers Day Consumer’s Day Immunisation Day Handicapped Day Azad Hind Fouz hoisted National flag at Mairang Social Empowerment Day 21 Forest Day 23 Bhagat Singh Day 24 World TB Day [263] April May June July August 27 4 5 7 10 11 14 15 25 1 5 8 9 12 13 17 20 24 31 5 14 26 27 1 4 6 8 21 23 26 29 1 6 8 9 15 16 20 Theatre Day Safety Day Maritime Day World Health Day Birthday of Hahnemann National Mothers’ Day Jaliwanwala Bag Dibash World Standards Day Words ‘Blood Bank’ first used May Day World Literacy Day Red Cross Day. Birthday of Henry Dunant & World Thalassaemia Day, Birthday of Rabindra Nath Tagore Birth Day of Rana Pratap Florence Nightingale Day Solidarity Day Telecommunication Day National Public Relations Day Commonwealth Day World No Tobaco Day Environment Day Birthday of Karl Landsteiner World Blood Donor Day Anti Drug Day Hellen Keller Day Birthday of Dr B C Roy & Doctors’ Day Bastille Day (French Revolution) Birthday of Dr Shyamaprasad Mukherjee Azad Hind Fauz Day Adoption of National Flag of India Birthday of Bal Gangadhar Tilak Kargil Day Indian Science Congress formed Non-cooperation Movement Launched by Mahatma Gandhi Hiroshima Day Quit India Day Nagasaki Day Independence Day Football Lovers’ Day Ronald Ross Discovered Malaria parasite in [264] 26 27 29 September 1 5 11 16 22 23 24 26 27 29 October 1 2 4 8 9 10 12 15 16 25 28 31 November 2 7 11 13 14 16 17 18 21 23 28 30 December 1 3 4 Jaharbrata by Rani Padmini at Chitorgarh Adi Grantha Sahib installed at Amritsar Golden Temple National Sports Day, Birthday of Dhyan Chand Rakhi Bandhan falls on full moon day of August INA formed Teachers’ Day Chicago address delivered by Swami Vivekananda Peace Day Alzeimer’s Day World Deaf Day Girl Child Day Birthday of Iswar Chandra Vidyasagar Birthday of Bhagat Singh/Tourism Day Matangini Hazra became martyr All India Voluntary Blood Donation Day Birthday of Mahatma Gandhi National Integration Day Postal Day/Air Force Day International Natural Disaster Reduction Day World Mental Health Day World Arthritis Day World White Cane Day World Food Day United Nations Day Birthday of Sister Nivedita Birthday of Sardar Ballab Bhai Patel Birthday of Guru Ramdas Birthday of C V Raman Birthday of Abul Kalam Azad Birthday of Ranjit Singh Children’s Day/Birthday of Pandit Nehru Birthday of Rani Laxmi Bai Death of Lajpat Rai Army Day First Postage Stamp of Independent India released Birthday of Shri Satya Sai Baba NCC Day Birthday of Sir Jagadish Chandra Bose Border Security Force Day International Day of Disabled Persons Navy Day [265] 10 11 18 25 27 Human Rights Day UNICEF Day Goa Liberation Day Christmas Day Janagana Mono was first sung at Calcutta session of Indian National Congress Occasions like Good Friday, Palm Sunday, Birthday of Guru Nanak Hajrat Mohammand. Various Pujas and Muharram follow luner calendar and as such these days fall on different dates in different years. Motivators should consult almanac every year to find out these days. Blood donor motivators should prepare his/her own calendar the calendar must have a relevance with the culture and people of the region. [266] Annexure X State AIDS Control Society (Blood Safety Units) Project Director, Andhra Pradesh State AIDS Cell Society, Directorate of Medical & Health Services, Sultan Bazar, Hyderabad-500 059, Andhra Pradesh project Director, Assam State AIDS Control Society, Khanapara, Guwahati-781 006, Assam Project Director, Andaman & Nicobar AIDS Control Society, G. B. Pant Hospital Complex, Port Blair-744 104, Andaman and Nicobar Islands Project Director, Arunachal Pradesh AIDS Control Society, Naharlagun, New ltanagar-791 110, Arunachal Pradesh Project Director, Bihar State AIDS Control Society, Health Department, New Secretariat, Patna-800 015. Bihar Project Director, State AIDS Preventive & Control Society, Union Territory of Chandigarh, General Hospital. Sector 16, Chandigarh-160 016 Project Director, Chatishgarh State AIDS Control Society, State Health Training Centre, Kalibari, Chhatisgarh Programme Officer (AIDS) & DHS, State AIDS Control Society, UT of Daman & Diu, Primary Health Centre, Mori Daman, Daman-3% 220. [267] Programme Officer (AIDS) Administration of Dadra & Nagar Haveli, Silvassa-396230. Project Director, Delhi AIDS Niyantran Samiti, 11, Lancer Road, Mall Road, Timarpur, Delhi -110054. Project Director, Goa State AIDS Control Society, Directorate of Health Services, Campal, Panaji-403 001, Goa Project Director, Gujarat State AIDS Control Society, Old Cardiology Building. Civil Hospital, Ahmedabad-380016, Gujarat Project Director, Haryana AIDS Control Society, State Health & FW Training Institute. Sector-6, Chandigarh, Panchkula. Haryana. Project Director, Himachal Pradesh State Society for AIDS Control, Health & Family Welfare Directorate, Shimla-171 009. Himachal Pradesh Project Director, J & K State AIDS Prevention & Control Society, Health & Medical Education Department, Old Secretariat, Jammu/ Srinagar., Jammu and Kashmir Project Director, Jharkhand State AIDS Control Society, Sadar Hospital Campus, Purlia Road, Ranchi - 834008 Project Director, Karnataka State AIDS Prevention Society, Directorate of Health & Family Welfare Services, Ananda Rao Circle, Bangalore-560009, Karnataka [268] project Director, Kerala State AIDS Control Society, IPP Building. Red Cross Road. Thiruvananathapuram-695037. Kerala programme Officer (AIDS) & DDHS, Directorate of Medical & Health Services, UT of Lakshadweep, Kavaratti-682555. project Director, Madhya Pradesh AIDS Control Society. DTC Building. J. P. Hospital Campus, Tulsi Nagar, Bhopal-462 003, Madhya Pradesh Project Director, Maharashtra State AIDS Control Society, Directorate of Medical Education, Govt. Dental Medical College. 3rd Floor, De Mello Road. Mumbai-400001, Maharashtra Project Director, Manipur State AIDS Control Society Medical Directorate, Lamphelpat Imphal. Manipur. Project Director, Meghalaya AIDS Control Society, 3rd Secretariat Building. Lower Lachumiere, Shillong- 793001, Meghalaya Project Director, State AIDS Control Society. Govt, of Mizoram, Aizawl-796 001, Mizoram Project Director, Nagaland State AIDS Control Society, Health & Family Welfare Deptt. New Secretariat Building. Kohima-797 001, NagaJand Project Director, Orissa State AIDS Control Society, Directorate of Health Services. Bhuvaneshwar-751 001, Orissa [269] Project Director, The Pondicherry AIDS Society, PHC Campus, Odien Salai, Pondicherry-605001. Project Director, Punjab State AIDS Control Society, Civil Hospital, Phase-IV, Mohali, Punjab. Project Director & DHS, Rajasthan State AIDS Control Society, Medical & Health Directorate, Swasthya Bhawan, Tilak Marg, “C” Scheme, Jaipur-302005. Rajasthan Project Director, Sikkim State AIDS Project Cell, STNM Hospital. Sikkim, Gangtok-737101, Sikkim Project Director, Tamil Nadu AIDS Control Society 4/7 Pantheon Road. Egmore Chennai - 600 008. Tamil Nadu Project Director, Tripura State AIDS Control Society. Health Directorate Building, Gurkhabasti, P. O. Kunjaban, Agartala, West Tripura-799006. Project Director, UP State AIDS Control Society. 2nd Floor, Maternity Home, Nawal Kishore Road, Hazratganj, Lucknow-226001. Uttar Pradesh Project Director, Uttaranchal State AIDS Control Society, Directorate General of Health Services, Chandan Nagar, Dehradoon, Uttaranchal Project Director, West Bengal State AIDS Prevention & Control Society, Shed “C” Bhawani Bhavan 34/1 Belvedere Road Kolkata- 700 027, West Bengal [270] Annexure XI Glossary ACD Acid Citrate Dextrose: anticoagulant preservative solution for donor blood, no longer much used because better solutions exist, permitting longer storage and better preservation (e. g. CPDA. CPDA1, and various additive solutions. ) AIDS Acquired Immunodeficiency Syndrome: chronic fatal disease caused by HIV infection. Albumin Predominant plasma protein, accounting for about 60% of the protein content of human blood. Plays an important role in maintenance of fluid balance and normal blood volume. Albumin, prepared by fractionation of human plasma, is one of the important blood products for transfusion. Antibody Protein, of the immunoglobulin class, which is produced in response to exposure to a specific antigen, and which is capable of binding specifically to that antigen. Anticoagulant Substance which prevents blood coagulation (clotting, fibrin formation!. Antigen Substance which is capable of provoking an antibody response. Apheresis Type of blood donation in which only one specific constituent (e. g. plasma, platelets) is retained for transfusion while the rest of the donated blood is returned to the donor. Australia antigen Term originally applied to what is now known as HBsAg (Hepatitis B Surface Antigen). Air embolism Obstruction of a blood vessel caused by air entering the circulatory system. Agglutination The clumping together of human red cells. Autologous transfusion The trnsfusion of any blood component that was donated by the intended recipient himself/herself. Blood bank Facility where blood can be collected, processed and stored for transfusion. Blood cells The cellular part of blood. Each cell is a living particle, enclosed in a membrane. [271] The principal blood cells ate red cells (erythrocytes), white cells (leucocytes) and platelets (thrombocytes). Blood centre Building or location specifically dedicated to blood collection, component production testing, storage, distribution, etc. Blood components Blood products, which can be routinely prepared by a BTS from donations of whole blood, which are made by separating specific parts of the blood which are useful for transfusion. Important components are red blood cells, platelets, plasma and cryoprecipitate. Blood donor Person whose blood is collected for transfusion. This term is most commonly used for donors of whole blood but may also be used for donors of plasma, platelets. etc Blood groups Term referring to systems of antigens on the cell surface, which may vary from person to person and which determine the compatibility of blood for transfusion. Blood products Any preparation which can be made from blood is a blood product. Blood products include blood components, plasma derivatives and a variety of preparations which are used for non-transfusion purposes (e. g. serological or cellular reagents). Blood substitutes Substances which can be used instead of blood. Blood transfusion Intravenous administration of blood or blood components to a patient. Blood Transfusion Service (BTS) Any organization designed to make blood and blood components available for transfusion. The typical BTS is involved in donor recruitment, blood collection, laboratory testing, component production, storage and distribution of blood products, and provides a service to multiple hospitals. Blood typing Laboratory testing to determine a person’s blood group. Centrifugation Technique, based upon spinning at high speed in a centrifuge, and thus exaggerating differences in specific gravity of different components, useful for separation of whole blood into its major components. Component therapy System of transfusion therapy (haemotherapy) based upon the availability of blood components and their active appropriate use for transfusion purposes. By implication most whole blood is used for making components. [272] CPD Citrate Phosphate Dextrose: anticoagulant preservative solution for donor blood. CPDA1 Citrate Phosphate Dextrose Adenine formula 1 (several other formulae are in routine or experimental use. ) CPD-Adenine is a better preservative than ACD or CPD but has, in many countries, been largely replaced by additive solutions. Cryoprecipitate One of the major blood components, prepared by slow thawing of fresh frozen plasma and separation of the resulting cold-insoluble precipitate from the rest of the plasma. This cryoprecipitate contains increased concentrations of factor VIII, von Willebrand factor and fibrinogen, fibronectin and cold-insoluble globulin. Cryoprecipitate has proved useful in the treatment of haemophilia A, von Willebrand’s disease and fibrinogen deficiency. Cytapheresis Apheresis procedure designed to collect specific cells from the donor’s blood. Chromosome A thread-like structure which carries genes. They are present in the nucleus of most living cells. Coagulation Clotting of blood which takes place when blood is collected in a dry container or reaches an open wound. Commercial or professional donor (seller) A donor who gives blood in return for money or other form of payment, Confidential unit exclusion The removal and disposal of a unit of blood after donation at the request of the donor. Demand Term referring to the blood product/service which is wanted/ordered/requested. Direct transfusion Obsolete technique whereby transfusion was accomplished by direct flow of blood from the donor into the patient. Directed donation Blood donation where the donor’s blood is reserved for a specific patient. Donor deferral Term referring to the non-acceptance of a prospective blood donor. Deferral may be temporary (for a specific time) or indefinite (no specific time can be assigned) or even permanent. Donor motivation Term applied to the process of public education and motivation for blood donation. [273] Donor recruitment Term applied to the whole process of ensuring that there will be a sufficient number of suitable blood donors. Donor retention Term applied to the process of ensuring that known donors will become regular donors and continue to donate. ELISA (ElA) Enzyme Linked Immunosorbent Assay. A test system designed to detect specific antibodies or antigens in a test sample. An important part of BTS technology since it became necessary and possible to detect the presence of infections transmissible by blood. Erythrocyte The red blood cell (the most numerous blood cell), which contains the red pigment haemoglobin and is responsible for transporting oxygen to the body tissues. Factor VIII Glycoprotein macromolecule, found in normal plasma and necessary for normal blood coagulation. This factor is absent or abnormal in haemophilia A arid is essentia] for effective treatment of this condition. Factor IK Essential for the treatment of haemophilia B. Fibrinogen Plasma protein which is converted to fibrin during the blood coagulation process. Fractionation The term ‘fractionation’ is sometimes incorrectly used to refer to ‘component production’, but this usage is confusing and best avoided. Fibrin Fine protein strands produced when soluble fibrinogen is acted upon by thrombin in the process of blood coagulation. Family replacement donor A donor who gives blood when it is required by a member of the donor’s family or community. HBV, HCV Hepatitis B and C Virus respectively. HBsAg Hepatitis B surface antigen; antigenic product of infection with hepatitis B which provides the basis for blood donor screening with the ELISA test for hepatitis B. Haemoglobin A red-looking fluid found in the red blood cells which is made up of iron (haem) and polypeptide chains (globin). [274] Haemolysis The breaking down (lysis) of the red cell membrane which liberates its content: haemoglobin. Haemolysis results from the reaction between a haemolytic antibody and its specific red cell antigen in the presence of complement. Haemolytic disease of the newborn (HDN) Severe, potentially life-threatening condition caused by maternal antibodies attacking and destroying the red cells of the fetus/newborn child. Haemophilia Hereditary disorder of blood coagulation. Haemophilia A (Factor VIII deficiency) and haemophilia B (Factor IX deficiency) are clinically identical but biochemically distinct; treatment depends upon specific plasma fractions for each condition. Hepatitis Inflammation of the liver. In the context of blood transfusion, hepatitis refers to the various forms of viral hepatitis which can be transmitted by blood transfusion, of which hepatitis B and hepatitis C are of the most serious concern. HIV Human Immunodeficiency Virus: retrovirus which predisposes to AIDS. Homologous Homologous transfusion refers to the transfusion of blood to a recipient of the same species. This term therefore applies to most instances of blood transfusion as currently practised, as distinct from autologous, heterologous and isologous transfusion. Heterozygous A condition where non-identical allelic genes are carried on homologous chromosomes. Homozygous A condition where two identical allelic genes are carried on homologous chromosomes. Immunogtobulin Generic term applying to the class of plasma proteins which comprises the antibodies. Immunoheamatology Literally, the study of the immunological aspect of blood. In the context of a BTS, immunohaematology has traditionally referred to the study of blood groups, their corresponding antibodies, and assurance of compatibility of blood destined for transfusion. Incidence The proportion of a specific population becoming newly infected by an infectious agent within a certain period of time. [275] Infectious disease markers The detectable signs of infection appearing in the bloodstream during or after infection. Lapsed donor A voluntary donor who. after making one or more donations, does not return to give blood, despite being requested to do so. Legislation The act of making laws. The distinction is emphasized between legislation and regulation. Leucocyte White blood cell. Low-risk donor The term commonly used in blood transfusion practice to describe a donor who is at low risk for transfusion-transmissible infections. Match A term used when testing the patient’s serum against the donor’s red cells and the donor’s serum against the patient’s red cells, prior to transfusion. This is better known as cross matching Naturally -occurring antibody An antibody that appears in the bloodstream without any known antigenic stimulus. Neutrophil A member of the family of white cells involved in fighting infection. Ova The reproductive egg cells of the female. Plasma The straw-colored protein-rich liquid part of blood in which the blood cells are suspended. Plasma derivatives High purity preparation of specific plasma proteins, prepared by plasma fractionation Plasma fractions. Plasma fractionation The process by which plasma derivatives are prepared. Effective fractionation requires large quantities of good quality plasma and increasingly high technology methods beyond the capability of most BTS’s. Plasma products A generic term applicable to both plasma derivatives and plasma prepared at the BTS level for transfusion purposes. Fhenotype The observable effect of the inherited genes: e. g. the blood group itself. [276] Rhesus (Rh) Important blood group system, also known as D, once the major cause of haemolytic disease of the newborn. Regular donor A donor who has given blood at least three times and who donates blood at least once a year. Risk behaviour Behaviour that exposes a person to the risk of acquiring transfusion transmissible infections. Serology Technology, commonly used in BTS laboratories, involving the interaction between antibodies (from serum) and antigens. Self-deferral The decision by a potential donor to wait until a condition that makes him/her unsuitable has resolved. Self-exclusion The decision by a potential donor not to give blood because he/she has engaged in risk behaviour or because of the state of his/her own health. Serum Plasma minus fibrinogen. Spermatozoa The reproductive cells of the male. Transfusion medicine Branch of medical science and medical education which deals specifically with blood transfusion and related scientific topics Transfusion-transmissible infection An infection that is potentially capable of being transmitted by blood transfusion. Thrombocyte A blood platelet, which plays a major role in the blood clotting mechanism. Voluntary donor A donor who gives blood, other blood components freely and voluntarily without receiving any payment in the form of money or a substitute for money. Whole blood Donor blood, with added anticoagulant/preservative solution, from which no components have been removed. Window period The period between infection and the development of detectable antigen or antibodies. [277] Name Index A Abanod Pictro 15 Agote 23 B Bagdasarov A 24. 27 Barnays EL 141 Behring E V 31 Bethune N 27 Bharucha Z S 33 Bhatia H M 33 Bhima 12 Blomback 31 Blundell J 20, 29 Bogdanov A 24 Borcelli 16 Bose S C. 182 Boyle R 19 Burke E 183 C Camaige A 179 Carrel A 21 Chattopadhyay A 33 Chelliah T 34 Coca A F 30 Coga A 19 Cohn E 31 D Decastello 22 Defoe D 141 Denis J B 20 Drew C 28 Dorairajan T 34 Duhsasana 12 E Ehrlichp 31 Elliot J 31 Erasisfratus 12 F Franklin B 141 Funtus B 27, 40 G Galen Galen 12, 15. 16 Gandhi MK 182 Ganguli L K 33 Gasellius F 20 Gupta ML 33 H Hamilton 141 Harvey W I5, 16 Herzberg F Hibler R Hicks B J Hirszfeld L Hood R Hustin A Hwang T 86, 88, 89 189 23 24 19 23 11 I Ijima H 29 Jefferson T Jorda D F Jolly J G J 141 27 33 K Kabir S A 34 King E 19 Krishen K S 33 L Landois L 21 Landsteiner K 22, 28, 30, 31 Lattes L 22 Lindman E 23 Levine P 28 Lewison 23 Linclon A 154, 182 Lord S 104 Lower R 19 M MalpighiM 16 Massari B 16 Mendel G 22 Moss 22 Macdonel 198 Macforlaned 31 McDonald 121 Mahabir 146 Maslow A 86, 87 Mavalankar V G 33 Menghini V 30 Metchnikoff E 31 Mollison PL 30 Moolgaokar L 32, 33 N Newton I 88 Nightingale F 106 Newmann E 31 [279] O Oliver PL 29 Ottenberg R 22, 30 P Paine T 141 Patton W C 32 Pool G J 31 Pope Innocent VIII 15 R Rajkumar R 34 Ranganaihan S 34 Reche O 24 Rostran A 104 Rowland R 35 S Schramn W 146, 147 Serventus M 15 Sen T 33 Skilifovsky N V 24 Soulier J P 29 Struli 22 Stetson 28 Subramanian T 34 Swift J 1 38 T Tata J R D 182 Tzanck A 29 U Unger L J 23 V Vani 33 Vaughan J 27 Vesalius 15 Vishnu Sharma 149 Vivekananda S 182 Vroom V H 88 W Walter C W 28 Washington G 19 Weiner A 28 Weslls WC 30 Wren C 19 Y Yudin S 24 [280]
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