Dextrans

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DEXTRANS
OPOLYMER
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SYNTHESIS
http://www.univ-toulouse.fr
Synthesising biocompatible products is a major stake for cosmetic and biomedical industries.
Pierre Monsan’s team in Toulouse (LISBP-INSA) has developed new enzymes transforming sugar
called glucan-saccharases. One specific enzyme (DSR-S) allows synthesising from saccharose a
glucose polymer called dextran, and obtaining in one step dextrans with controlled molecular weight
and various structures (types of bond, size).
These molecules of dextran, produced through an environmentally-friendly process, can be used for a
large range of applications in cosmetics, biomedical and chemical industries: proven biocompatibility,
controllable viscosity which is a key factor for cosmetic formulation, active ingredient for water
retention, stimulation of cell growth as a major property for tissue regeneration, exclusion
chromatography, biopolymer substituting synthesised polymer.
A partner is sought to contribute to the development of
this technology in the fields of cosmetics and chemistry.
Development stage
Proof of concept done
Intellectual property rights
Patents filed on 19/12/2001 and 08/02/2006
International protections:
WO 02/074943 and WO 07/091178
Joint ownership INSA-INRA-CNRS
Project Manager / Laboratory
Dextran molecular structure
Pierre MONSAN
LISBP
- INSA (National Institute of Applied Sciences), Toulouse
http://www.insa-toulouse.fr/fr/recherche/labo/lisbp.html
Advantages
Natural process
Fields of application
- Active ingredient for water retention
- Thickening agent
- Stimulation of cell growth
- Tissue regeneration
- Emulsion stabilisation
- Exclusion chromatography
Easy to implement
Biocompatible
Controlled viscosity
Collaborations
Licence agreement - Technical collaboration
Targeted Industries
- Cosmetics
- Biomedical
- Chemistry
Active ingredient for water retention
and tissue regeneration
http://www.insatoulouse.fr
Technology transfer manager
Claire MÉTAIS
Université de Toulouse Valorisation
+33 (0)5 34 41 35 36
[email protected]