Thousands of Lipids. One Name to Remember: Lipidyzer

LIPIDYZER TM PL ATFORM POWERED BY METABOLON ®
Join Us at Metabolomics 2015 and
Meet Our Experts in Lipidomics and
Metabolomics Applications
Join the SCIEX Omics Community to
continue the conversation. There you
Join our luncheon workshop:
will find blogs, discussions, and interest
Next-Generation Lipidomics: An Automated Solution that Rapidly Identifies and Quantitates Over a
Thousand Molecular Species
groups dedicated to Life Science Research.
Wednesday, July 1, 11:30 AM -12:45 PM — GRAND BALLROOM F/G
learn from others.
View our Lipidomics and Metabolomics poster presentations:
Visit sciex.com/community.
Post your questions, share content and
Monday, June 29, 6:30 - 8:30 PM
#048 A Novel MSMSALL Workflow for Unbiased Lipidomics Discovery for Serum Biomarkers
Leo Jinyuan Wang 1, Paul Baker 1, Clementina Mesaros 2, 4, Andrew J. Worth 2,3 and Ian A. Blair 2
1
4
SCIEX, Redwood City, CA; 2 University of Pennsylvania, Philadelphia, PA; 3 Center for Excellence in Environmental Toxicology, Philadelphia, PA;
A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA
#058 A Novel Lipid Screening Platform Allowing a Complete Solution for Lipidomics Research
Alex Connor 1, Baljit K. Ubhi 2, Eva Duchoslav 3, Fadi Abdi 4, Leo Wang1, Paul Baker 4 and Steve Watkins1
1
Metabolon, West Sacramento, CA ; 2 SCIEX, Redwood City, CA; 3 SCIEX, Ontario, Canada; 4 SCIEX, Framingham, MA
#288 Quantitative and Qualitative Metabolomics for the Investigation of Intracellular Metabolism
Baljit K. Ubhi 1, Aaron Hudson 2 and Douglas McCloskey 3
SCIEX, Redwood City, CA ; SCIEX, Framingham, MA; Department of Bioengineering, University of California, San Diego, CA
2
3
Wednesday, July 1, 12:45-2:45 PM
#332 An Autonomous Workflow for Untargeted Metabolomics Profiling
Baljit K. Ubhi1, H. Paul Benton 2, Duane Rinehart 2 and Gary Siuzdak2.
SCIEX, Redwood City, CA; 2 Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA
1
#372 SelexIon® Technology: Mobility Separation of Leukotriene Isomers
Cyrus Papan1, Sebastian Fabritz 1, Baljit K. Ubhi 2, Michael Driscoll 2 and Martin Giera 3
SCIEX, Darmstadt, Germany; 2 SCIEX, Redwood City, CA; 3 Center for Proteomics and Metabolomics, Leiden University Medical Center (LUMC),
Leiden, The Netherlands
1
#536 Targeted Metabolic Profiling Using High-Resolution Accurate Mass Database to Identify and
Confirm Potential Biomarkers in Rose and Sunflower Plant Extracts
Jeffrey D. Miller 1, Cyrus Papan 2, Dr. Jens Pfannstiel 3, Iris Klaiber 3, Baljit K. Ubhi 4, Christie Hunter 4, Shaokun Pang 4,
Emmanuel Varesio 5, Tobias Bruderer 5 and Gerard Hopfgartner 5
SCIEX, Framingham, MA; 2 SCIEX, Darmstadt, Germany; 3 Universität Hohenheim, Serviceeinheit des LSC, Stuttgart, Germany;
SCIEX, Redwood City, CA; 5 University of Geneva, Geneva, Switzerland
1
4
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trademark of Metabolon, Inc. AB SCIEX™ is being used under license.
RUO MKT-07-2208-B 6/2015
Tuesday, June 30, 12:45-2:45 PM
1
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Thousands of Lipids.
One Name to
Remember: Lipidyzer™
LIPIDYZER NEXT-GENERATION LIPIDOMICS PL ATFORM
Metabolomics
2015
June 29 -July 2
Attend our Luncheon Workshop on
Wednesday, 11:30 AM -12:45 PM
Grand Ballroom F/G
See us at Booth #5
Review our Presentation
Roster, page 4
The new Lipidyzer™ Platform enables you to rapidly and accurately differentiate
and quantitate over a thousand lipid species, and translate your data into
knowledge with ease and efficiency.
Finally, All-in-One
Lipid Analysis is Within
Your Reach
Developed by SCIEX and powered by Metabolon®,
the Lipidyzer™ Platform enables labs of all sizes to
perform next-generation lipidomics. The all-in-one,
Lipid classes and their
chemical structures
turnkey, benchtop platform can run hundreds of
samples and quantify over a thousand lipid species
A Complete Solution —from Sample
to Biology
O
O
R1
• Proprietary
R
N+
H
O
R2
O
O-
O
R2
O
O
O
O
O
HO
go from sample to biologically relevant knowledge.
O
O
R2
H
Triacylglycerols
Phosphatidylethanolamines
R
There’s simply no faster or more efficient way to
OH
P
O-
R3
O
O
R1
NH2
H
O
O
O
R2
O
O
Work faster and smarter
cal insight for 100s of samples in days, not wee
i
g
o
l
o
i
b
ks
Gain
SelexION® Technology for effective
separation across lipid classes
•
data sharing and access to scientific specialists.
O
P
O
Platform delivers expert data analysis via cloud-based
Diacylglycerides
O
Lipidyzer Platform makes lipid analysis easy and seamless. The simple, integrated
workflow allows you access to comprehensive data, quickly and confidently,
Lipidyzer Next-gen lipidomics solution Components | Workflow | Benefits INFOGRAPHIC 4.21.15
while expert analysis services provide you with the assurance to gain accurate
biological insight.
Only the Lipidyzer™ Platform features:
quickly, efficiently, and accurately. In addition, the
Phosphatidylcholines
One Streamlined
Workflow for
Peak Performance
Ready-to-use sample preparation kits with
standardized procedures for up to ten lipid classes
•
Custom-designed software for easy species
identification and biological interpretation of results
Samples
Prepare
Samples
Log Samples
& Select
Experiments
Differentiate
& Quantitate
Interpret
Biological
Data
Access
Consulting
Services
Unravel
Mechanism
of Action
Next-generation lipidomics at your fingertips.
Learn more at sciex.com/ lipidyzer
H
O
ID Biomarkers
Sphingomyelins
H
OH
O
O
R
P
O
HO
ID Novel Targets
N+
H
NH
O
Lysophosphatidylcholines
O
R
Lysophosphatidylethanolamines
O
O
O
HO
P
O-
H
O
O
N+
O
R
O
P
O
HO
O
HO
NH2
H
Ceramides
H
OH
NH
H
Cholesteryl Esters
O
H
R
• Ensures optimum data
acquisition conditions
• Lipidomics
workflow-driven
software interface
LC-MS/MS SYSTEM WITH
SELEXION TECHNOLOGY
• Performs separations
across all classes and
species
• Differentiates and
quantifies over a
thousand lipid species,
rapidly and accurately
• Ensures accuracy
of results
H
O
OH
• Automatic method
selection based on
lipid class
• Delivers unparalleled
sensitivity
H
H
R
LIPID SELECTION
• Standardized
procedures
• Ensures
reproducibility
O
Free Fatty Acids
SAMPLE PREP KITS
• Simplified operation
OH
R
Knowledge
H
O
For Research Use Only. Not for use in diagnostic procedures.
CUSTOM SOFTWARE
• Reports quantitative
results
• Provides confident
species identification
• Built on one of the
world's best selling
LC-MS/MS mass
spectrometers platforms
EXPERT ANALYSIS AND
CONSULTING
• Facilitates data analysis
to understand biological
significance
• Provides access to
scientific specialists