GENOMICS
X-MAN® Cell Lines
Disease Models for Your Research
Over 1,200 cell lines containing defined
genomic alterations available, genetically
validated and ready to ship
Presenting the X-MAN human cell line collection: over 1,200 diploid and
haploid cell lines containing defined genomic modifications. An unparalleled
resource for the characterization of genes and their role in disease biology
and drug response.
t + 44 (0)1223 655 580 (UK) or +1 (844) 655-7800 (USA)
f + 44 (0)1223 655581
e [email protected]
w www.horizondiscovery.com
Horizon Discovery, 7100 Cambridge Research Park, Waterbeach, Cambridge, CB25 9TL, United Kingdom
X-MAN®
Key benefits
•
Study loss and gain of function at the endogenous level
•
Easily attribute phenotypes directly to genomic modifications (mutant vs control cell lines)
•
Accelerate your research by choosing from hundreds of cell lines available
•
Target identification via phenotypic and synthetic lethality screens
•
Target validation with patient relevant disease models
•
Identification of responsive or resistant patient populations
•
Analysis of expression, protein interactions and localization using endogenously tagged genes
Available individually or as extensive gene family and signaling pathway panels.
X-MAN®
DNA Damage
Autophagy
Kinases
mTOR
Caspases
Oncogenes & Tumor suppressor
TNF alpha
Sialylation Pathway
Epigenetics
RAB proteins
Ubiquitination
Solute Carriers
And many more
© X-MAN® Human Cell Line Disease Models for Your Research 2015 v-02
t + 44 (0)1223 655 580 (UK) or +1 (844) 655-7800 (USA)
f + 44 (0)1223 655581
[email protected]
w www.horizondiscovery.com
Horizon Discovery, 7100 Cambridge Research Park, Waterbeach, Cambridge, CB25 9TL, United Kingdom