SBI4U – Molecular Genetics Unit
Name: __________________________________
Teaching DNA Structure and DNA Replication Assignment Objective of the Task: Your task is to teach someone, not currently taking Grade 12 Biology (preferably an adult), the concept of DNA and how it undergoes replication. The key to effectively teaching a concept to someone is understanding it first! Task: You must hand in the following items: (1) Teaching Notes q Notes should be your own, not those taken from the resources provided to you q Includes all the key points of the topic q Key points are explained in adequate detail q Can be typed or hand-­‐written (2) Teaching Outline q A step-­‐by-­‐step synopsis of how you will conduct the lesson. A blank Word document template file will be provided for you to fill in. (3) Teaching Aids q Should be more than just lecturing and PowerPoint presentation -­‐ Think outside the box! An interactive manipulative(s) is required to achieve a Level 4 mark. q Your teaching aid should be demonstrating your understanding of the content q Correct scientific terminology should be used q Teaching Aid must be separate from Teaching Notes q The delivery of the lesson may include, but not limited to, the following formats: § Interactive models, visual aids, animations, PowerPoint presentation, interactive website (multiple pages) or any alternative format (see teacher for approval) (4) Assessment Tool w/ Answer Key q Does it effectively measure what was taught? q Is it geared towards the target audience? q Questions relate to the most important concepts taught q Not based on how well your student performs, but hand in the completed assessment (5) References q References are required q To be written in APA format (6) Completed Survey q No marks will be allocated for this section; it will only be used for feedback Accommodations: The lesson must have been taught to someone. If you are unable to find someone who is eligible to teach it to, please see me well before the due date and we can set up an alternative teaching opportunity! Marking Scheme – see rating scale Key Dates: q Q & A -­‐ Thursday, February 25th q DNA Replication Quiz – Mon. February 29th q Submission of Teaching Notes – Tues. February 29th Due Date: _________________________________________ (Ultimate Deadline) Sources of Info: q Textbook: pg. 210-­‐223 / pg. 223 #1-­‐8 / pg. 230 #1, 4, 6, 10, 11, 14, 15 (draw it), 21 q See class website for animations DNA Replication Worksheet 1. Define semi-­‐conservative replication. 2. Define the roles of the following key players found in DNA replication: ∗
DNA helicase ∗
DNA gyrase ∗
Single strand binding proteins (SSBs) ∗
DNA polymerase III ∗
RNA primase ∗
DNA ligase 3. What are the starting points of DNA replication called? 4. Why is it necessary to have more than one location for DNA replication to occur on the same DNA molecule? 5. Differentiate between replication fork and replication bubble? Draw a diagram to illustrate this. 6. What does anti-­‐parallel mean with respect to the structure of DNA? 7. What is the purpose of the RNA primers? 8. In which direction does DNA replication occur? 9. How does DNA replication obtain its energy to conduct the addition of nucleotides to the growing chain? 10. What are Okazaki fragments? 11. What are the differences between the lagging strand and the leading strand? 12. What enzymes are involved in proofreading once DNA replication is complete? 13. Complete the replication fork diagram located below. 14. Summarize the list of events that must occur before the elongation stage of replication. 15. Explain the elongation stage of replication. Your answer should include a discussion of leading strand, lagging strand, Okazaki pieces and RNA primer.