MATERIAL SAFETY DATA SHEET
04/01/2016
1- PRODUCT & COMPANY INFORMATION
Product Name
(S)-(-)-Indoline-2-Carboxylic Acid
Catalog Number
OC-0157
Company
OmegaChem inc.
480 rue Perreault
Saint-Romuald (Quebec) Canada G6W 7V6
Tel. (418) 837-4444
Fax (418) 837-5196
[email protected]
www.omegachem.com
2 – COMPOSITION / INGREDIENTS
Substance Name
(S)-(-)-Indoline-2-Carboxylic Acid
CAS Number
SARA 313
Formula
79815-20-6
No
C9H9NO2
3 – HAZARDS IDENTIFICATION
Emergency Overview
Toxic (USA) Harmful (EU).
Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact. Harmful: danger of serious
damage to health by prolonged exposure if swallowed. Possible risk of impaired fertility. Harmful if swallowed.
HMIS rating (0,1,2,3 or 4)
• Health : 3*
• Flammability : 0
• Reactivity : 0
• Special hazard(s) :
NFPA rating (0,1,2,3 or 4)
• Health : 3
• Flammability : 0
• Reactivity : 0
• Special hazard(s) :
*additional chronic hazards present.
For additional information on toxicity, please refer to section 11.
4 – FIRST AID
Oral exposure
Inhalation exposure
Dermal exposure
Eye exposure
If swallowed, wash mouth with water, provided the person is conscious and call a physician.
Remove the person to fresh air. If not breathing give artificial respiration. If breathing is difficult,
give oxygen.
Immediately wash skin with soap and large amounts of water.
Flush eyes with large amounts of water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
MATERIAL SAFETY DATA SHEET
page 2 of 4
5 – FIRE FIGHTING MEASURES
Flash point
Autoignition temperature
Flammability
N/A
N/A
N/A
Extinguishing media
Firefighting
Carbon dioxide; dry chemical powder or appropriate foam. Water spray.
Protective equipment:
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin
and eyes.
Specific hazard(s):
Emits toxic fumes under fire conditions.
6 – ACCIDENTAL RELEASE MEASURES
Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves.
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash
Method for cleaning up
spill site after material pickup is complete.
Personal precautions
Procedure in case of
leak or spill
Evacuate area.
7 – HANDLING AND STORAGE
Handling
Storage
User exposure: avoid breathing dust. Avoid contact with eyes, skin, and clothing. Avoid
prolonged or repeated exposure.
Suitable: keep tightly closed.
8 – EXPOSURE CONTROLS / PPE
Engineering controls
Personal protective
equipment
General hygiene
measures
Safety shower and eye bath.
Mechanical exhaust required.
Respiratory: government approved respirator.
Hand: rubber gloves.
Eye: chemical safety goggles.
Wash thoroughly after handling.
9 – PHYSICAL / CHEMICAL PROPERTIES
Appearance
Molecular Weight
pH
Boiling point
Melting point
Freezing point
Vapor pressure
Vapor density
Saturated Vapor Conc.
SG / Density
Odor threshold
Volatile
VOC content
Water content
Solvent content
OmegaChem Inc.
Solid
163.18 AMU
N/A
177°C (dec)
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Evaporation rate
Viscosity
Surface tension
Partition coefficient
Decomposition temp.
Flash point
Explosion limits
Flammability
Autoignition temp.
Refractive index
Optical rotation
Solubility
Miscellaneous
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
-114°, c = 1, HCl (1N)
N/A
N/A = not available
OC-0157
MATERIAL SAFETY DATA SHEET
page 3 of 4
10 – STABILITY AND REACTIVITY
Stability
Hazardous
decomposition
products
Stable: Stable.
Materials to avoid: strong oxidizing agents.
Carbon monoxide
Carbon dioxide
Nitrogen oxides.
11-TOXICOLOGICAL INFORMATION
Route of exposure
Skin contact
Skin absorption
Eye
Causes skin irritation.
May be harmful if absorbed through the skin.
Causes eye irritation.
May be harmful if inhaled. Material is irritating to mucous membranes and upper respiratory
Inhalation
tract.
Ingestion
Harmful if swallowed.
Sensitization
Skin: May cause allergic skin reaction.
Signs and symptoms of To the best of our knowledge, the chemical, physical, and toxicological properties have not been
exposure
thoroughly investigated.
Toxicity data
Oral
Rat
360 mg/kg
LD50
Irritation data
Eyes
Remarks: Moderate irritation effect
12 – ECOLOGICAL INFORMATION
Acute ecotoxicity test
Test Type: LC50 Poisson
Species: Pimephales promelas (Fathead minnow)
Time: 96 h
Value: 26.1 mg/l
13 – DISPOSAL CONSIDERATIONS
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix
Appropriate method of
the material with a combustible solvent and burn in a chemical incinerator equipped with an
disposal of substance
afterburner and scrubber. Observe all federal, state, and local
or preparation
environmental regulations.
14 – TRANSPORT INFORMATION
DOT
IATA
Proper shipping name: none
Non-hazardous for transport: this substance is considered to be non-hazardous for transport.
Non-hazardous for air transport
OmegaChem Inc.
OC-0157
MATERIAL SAFETY DATA SHEET
page 4 of 4
15 – REGULATORY INFORMATION
EU
USA
Canada
Symbol of Danger: Xn
Indication of Danger: Harmful.
R: 43 48/22 62
Risk Statements: May cause sensitization by skin contact.
Harmful: danger of serious damage to health by prolonged exposure if swallowed. Possible risk
of impaired fertility.
S: 22 25 26
Safety Statements: Do not breathe dust. Avoid contact with eyes. In case of contact with eyes,
rinse immediately with plenty of water and seek medical advice.
Indication of Danger: Toxic (USA) Harmful (EU).
Risk Statements: Irritating to eyes, respiratory system and skin. May cause sensitization by skin
contact. Harmful: danger of serious damage to health by prolonged exposure if swallowed.
Harmful if swallowed. Possible risk of impaired fertility.
Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice. Wear suitable protective clothing.
SARA LISTED : No
WHMIS Classification: This product has been classified in accordance with the hazard criteria of
the CPR, and the MSDS contains all the information required by the CPR.
DSL: No
NDSL: No
16 – OTHER INFORMATION
The product is to be used for R&D only. Not for drug, household or other uses.
The above information is based on the present state of our knowledge and is applicable to the product with regard to
appropriate safety measures. It is believed to be correct but does not purport to be inclusive and shall be used only as a
guide.
OmegaChem Inc. shall not be held liable for any damage resulting from handling or from contact with the above
product.
OmegaChem Inc.
OC-0157