Preclinical Modelling Workshop
for Regenerative Medicine
Challenges, Economic Opportunities and UK Capabilities
“all models are wrong, but some are useful” George E P Box
Keynote speaker: Dr Marina
Dobrovolskaia (NIH)
Nanotechnology Characterization Laboratory, National Cancer Institute, Maryland, US
Marina’s experience includes validation and performance qualification of in vitro
and ex vivo assays to support preclinical characterization of nanoparticles
Dr Michael Sullivan
Dr Thomas Becker
Dr Michaela Sharpe
Prof Alicia El Haj
Darren Carwardine
Dr Nick Forsyth
Dr Divya Chari
Dr Neill Liptrott
Claire Crowley
Charles River Laboratories
John Egan
Dr Patrizia Ferretti
Prof Frank Barry
Dr Alan Burns
Dr Ilida Ortega
Propath
Thu-Fri
27-28th
Feb 2014
Technology Strategy Board, Funding for non-animal model technologies
Centre for Neuroregeneration, University of Edinburgh
Cell Therapy Catapult
Keele University
Bristol University, Cell transplantation for pet dog spinal cord injury
Keele University, In vitro models employing in vivo oxygen levels
Keele University, Organotypic tissue slice models of neural injury
University of Liverpool, Immunogenicity/haemocompatibility of nanomaterials
UCL, Tissue engineered trachea – ‘world’s first synthetic organ’
Off-the-shelf animal models for regenerative medicine
HealthTech and Medicines Knowledge Transfer Network
Development and Regeneration group, UCL, Chick models
Regenerative Medicine Institute (REMEDI), NUI Galway
UCL, In vivo and ex vivo gut models for enteric nervous system stem cell therapy
Sheffield University, Ex vivo model of corneal stem cell niches for regeneration
Q&A session: Designing the best preclinical testing strategies
Presenting opportunities are available for students and early career post-docs to discuss their models
This workshop offers:
Details of significant funding available for the development of non-animal technologies
Results of a nationwide survey assessing the UK’s capacity for preclinical modelling
Cutting edge models for assessing the efficacy of regenerative therapies
Details of commercial off-the-shelf models/assays for testing regenerative therapies
Advice on developing models to meet regulator expectations
Networking opportunities throughout between academic, clinical and commercial investigators
Opportunities to ‘steer’ the development of new preclinical models to meet your needs
Discussions will address:
What data are required for clinical trial approval?
How are assays/models validated as having predictive value?
Which animal models have failed, why, and what are the alternatives?
Exploiting gaps in the preclinical marketplace for development of models/assays/consumables
Enquiries and registration: Dr
Stuart Jenkins, Keele University
[email protected]
01782 733678
Sponsor: Prof
@Keele Hall
Keele University ST5 5BG
David Williams, Loughborough University
Attendance: 1 day for £29; both days £58. Parking available.
On-campus accommodation available: £41/night (£99 for 2 days, 1 night)
E-TERM: Engineering, Tissue Engineering
and Regenerative Medicine