Robert M. Kelly
MASTER’S STUDENTS
Student
1. David Sherry
2.
3.
4.
John
Godshalk
Characterizati
on of bacteria
from extreme
enviro
Stuart A.
Hurwitz
Francis J. Sturm
B.S. Degree
Johns
Hopkins
N.C. State
Grad. Degree
M.S., 1983
(JHU)
M.S., 1984
(JHU)
Thesis Topic
The effects of diffusion and intrinsic kinetics on production rate of
aspartic acid by aspartase in Escherichia coli
Characterization of bacteria from extreme environments
Last Known/Current Employment
Anheuser-Busch, St. Louis, MO
Maryland
(Chemistry)
Coast Guard
Academy
(Chemistry)
M.S., 1985
(JHU)
M.S., 1986
(JHU)
The effects of temperature and pressure on the growth of the
extreme thermophile Sulfolobus acidocaldarius
Growth of extremely thermophilic archaebacteria in a hyperbaric
helium bioreactor
IBM, RTP, NC
Cognizant Technology Solutions,
Wash., DC
5.
A.K.
Parameswaran
IIT-Kanpur
M.S., 1987
(JHU)
6.
Wei-wen
(Winston) Su
NTU, China
M.S., 1987
(JHU)
Extremely thermophilic archaebacteria of the genus Pyrodictium:
Effect of yeast extract and hydrogen and carbon dioxide partial
pressures on growth and sulfide production
Engineering studies of extremely thermophilic archaebacteria:
Sulfolobus acidocaldarius and Pyrococcus furiosus
7.
Balrina Malik
M.S., 1988
(JHU)
Growth and gas production for the extremely thermophilic
archaebacterium: Pyrococcus furiosus
8.
Anne Robinson
IIT-New
Dehli
(Chemistry)
Johns
Hopkins
Johns
Hopkins
Bucknell
M.S., 1989
(JHU)
M.S., 1989
(JHU)
M.S., 1991
(JHU)
M.S., 1991
(JHU)
Isolation and characterization of proteolytic enzymes from the
hyperthermophilic archaebacterium, Pyrococcus furiosus
Isolation and characterization of amylolytic enzymes from the
hyperthermophilic archaebacterium, Pyrococcus furiosus
Growth physiology and biochemical studies of a novel, deep sea
hyperthermophilic archaebacterium, ES4
Characterization of metabolic patterns in the hyperthermophilic
archaebacterium, Pyrococcus furiosus
9.
Henry
Costantino
10. Jeffrey
Schuliger
11. Lesley
Snowden-Swan
Washington
The Biologics Consulting Group,
Alexandria, VA
U.S. Coast Guard, Homeland
Security. Washington, DC
Department of Molecular
Biosciences and Bioengineering,
University of Hawaii
Schering-Plough, Union, NJ
CHE, Tulane University
Alkermes, Inc., Waltham, MA
US Army, Aberdeen, MD
PNNL, Richland, WA
12. V. Muralidharan
IIT-Madras
13. Olga
D'Hennezel
14. Pascal Leduc
UTC, France
15. Rockey
Bandlish
Ohio State
(Biochem.);
Emory
(Pharmacy)
(M.S.)
Louisiana
Tech
M.S., 1998
(NCSU)
Florida
M.S., 1999
(NCSU)
16. Lance Driskill
17. Jun Gao
UTC, France
M.S., 1992
(JHU)
M.S., 1993
(NCSU)
M.S., 1994
(NCSU)
M.S., 1998
(NCSU)
Interspecies hydrogen transfer in cocultures of extremely
thermophilic bacteria
Characterization of a novel thermostable DNA polymerase from a
hydrothermal vent microorganism
Purification and characterization of an -galactosidase and an
exo--mannanase from the hyperthermophilic eubacterium
Thermotoga neapolitana strain 5068
Comparative study of glucose isomerases from the mesophile
Streptomyces murinus and hyperthermophile Thermotoga
neapolitana for high fructose corn syrup production
BHP Billiton, Houston, TX
Beta-specific glycosyl hydrolases from the hyperthermophilic
archaeon Pyrococcus furiosus and their role in utilizing
carbohydrate nutrient sources
Characterization of a hyperthermophilic chitinase and its binding
domain
Diagnostic Radiology, Plano, TX
Merck & Co., Durham, NC
Bonduelle, Quebec, Canada
Illumina, San Diego, CA
TVS, Inc., RTP, NC
PH.D. STUDENTS
1.
2.
Craig N.
Schubert
John R. Lindner
3.
Ilse I.
Blumentals
4.
Richard N.
Schicho
Stephen H.
Brown
Tonya L.
Peeples
Sheryl Halio
Bauer
J. Michael Hess
5.
6.
7.
8.
UCSD
Johns
Hopkins
Simon
Bolivar,
Caracas, VZ
(Biology)
Duke
(Chemistry)
MarylandCollege Park
N.C. State
Tufts
Grove City
College
Penn State
(M.S.)
Ph.D., 1988
(JHU)
Ph.D., 1988
(JHU)
Ph.D., 1990
(JHU);
Postdoc,
1991
Ph.D., 1992
(JHU)
Ph.D., 1992
(JHU)
Ph.D., 1994
(JHU)
Ph.D., 1995
(NCSU)
Ph.D., 1997
(NCSU);
Postdoc 1998
Experimental studies of selective acid gas removal
Mathematical model for selective chemical absorption of H2S from
CO2 in packed columns
Characterization of growth physiology, cell-sulfur interaction and
SDS-resistant proteolytic activity in the hyperthermophilic
archaebacterium Pyrococcus furiosus
Bioenergetic studies of sulfur reduction in the hyperthermophilic
archaebacteria Pyrodictium brockii and Pyrococcus furiosus
Saccharidases from high-temperature bacteria: Physiological and
enzymological studies
Bioenergetic studies of hyperthermophilic and extremely
thermoacidophilic archaea as related to coal desulfurization
Cloning, sequencing, expression and physiological characterization
of protease S66 from the hyperthermophile Pyrococcus furiosus
Thermostabilization and thermoactivation of free and immobilized
xylose isomerases from hyperthermophilic microorganisms
Dow Global Technologies,
Midland, MI
TerumoBCT, Denver, CO
Glaxo-SmithKline, Philadelphia,
PA
Bristol Myers Squibb, MA
Novozymes Biotech, Davis, CA
Prof., Chemical and Biochemical
Engineering, U Iowa
Biogen-IDEC, Cambridge, MA
Novozymes, Franklinton, NC
9.
Michael W.
Bauer
10. Kristina D.
Rinker
Cornell
11. Chae Han
UT-Austin
12. Paula M. Hicks
Dayton
13. Kimberley
Rollins Parker
NC A&T;
NC State
(M.S.)
NC State
14. Amitabh C.
Sehgal
15. Swapnil R.
Chhabra
16. Marybeth Pysz
Alabama
IIT Bombay
17. Lara S. Madding
SUNY
Buffalo
Virginia
18. Keith R.
Shockley
New Mexico
State
19. Kevin L. Epting
Penn State
N.C. State
(M.S.)
Simon
Bolivar,
Caracas, VZ
(Biology)
Mt. Holyoke
College
(Biochem.)
Cornell U
(Biol & Ag
Engr)
20. Clemente
Montero
21. Shannon B.
Conners
22. Matthew R.
Johnson
Ph.D., 1997
(NCSU)
Ph.D., 1998
(NCSU)
Hemicellulases from hyperthermophilic archaea: Genetic,
biomolecular, physiological and engineering characterization
Bioenergetic and physiological studies of hyperthermophilic archaea
Ph.D., 1998
(NCSU)
Ph.D., 1998
(NCSU)
Physiological studies of extremely thermoacidophilic
microorganisms under normal and stressed conditions
Genetic, biochemical, and biophysical characteristics of intracellular
proteases from the hyperthermophilic archaeon Pyrococcus furiosus
and the hyperthermophilic bacterium Thermotoga maritima
-specific
galactomannan-degrading enzymes from hyperthermophilic
microorganisms
Effect of reaction environment on biocatalysis and enantioselectivity
of hyperthermophilic esterases
Physiological, biochemical, and biotechnological characterization of
glycoside hydrolases from the hyperthermophilic bacterium
Thermotoga maritima
Transcriptional analysis of biofilm formation and stress response in
hyperthermophilic microorganisms
Role of 1 subunit in function and stability of the 20S proteasome
from the hyperthermophilic archaeon Pyrococcus furiosus
Ph.D., 2000
(NCSU)
Ph.D. 2002
(NCSU)
Ph.D. 2002
(NCSU)
Ph.D. 2003
(NCSU)
Ph.D.
2003
(NCSU)
Ph.D. 2004
(NCSU)
Biogen-IDEC, Cambridge, MA
Assoc. Prof., Department of
Physiology and Pharmacology, U
Calgary
Amgen, Newbury Park, CA
Evolva, Inc., San Francisco, CA
Biogen IDEC, RTP, NC
Novartis, Holly Springs, NC
JBEI, LBL, Berkeley, CA;
Graduate student, Northwestern
Univ. - Aanlytics
Stem CentRx, South San
Francisco, CA
Postdoc, Duke U Medical School
Functional genomics investigation of microbial physiology in the
hyperthermophilic microorganisms Pyrococcus furiosus and
Thermotoga maritima
Xylose (glucose) isomerases from Thermotoga species:
Biochemical, biophysical and bioprocessing issues
NIEHS, RTP, NC
Ph.D. 2005
(NCSU)
Molecular microbial ecology of the hyperthermophilic bacterium
Thermotoga maritima: Transcriptional and physiological response to
antibiotic challenge and inter-species interactions
Dept. of Clinical Microbiology,
Albany Med Center
Ph.D. 2005
(NCSU)
Carbohydrate utilization pathway analysis in the hyperthermophile
Thermotoga maritima
SAS Institute, Cary, NC
Ph.D. 2005
(NCSU)
Intercellular communication in hyperthermophilic microorganisms
Biogen IDEC, RTP, NC
Ph.D. 2004
(NCSU)
Sartarious, Harrisburg, PA
23. Donald A.
Comfort
Case
Western
24. Joshua R.
Michel
UC-Davis
25. Chung-Jung
(Hank) Chou
NTU Taiwan
26. Sabrina
Tachdjian
27. James M. Harris
Univ. of
Lyon,
France
N.C. A&T
28. Steven R. Gray
UVa
29. Kathryne S.
Auernik
Notre Dame
30. Amy L.
VanFossen
Delaware
31. Derrick L. Lewis
South
Alabama
32. Charlotte R.
Cooper
South
Carolina
Ph.D. (NCSU)
33. Inci Ozdemir
Middle
Eastern U.,
Turkey
Virginia
Tech
UDCT
Ph.D. (NCSU)
34. Andrew D.
Frock
35. Jaspreet S.
Notey
Ph.D.
2006
(NCSU)
Ph.D.
2007
(NCSU)
Ph.D.
2007
(NCSU)
Ph.D.
2007
(NCSU)
Ph.D.
2009
(NCSU)
Discovery, functional genomics, and characterization of alphaspecific glycosyl hydrolases from hyperthermophilic microorganisms
Department of Chemical and
Materials Engineering, U Dayton
Identification, characterization, and physiologic analysis of
proteolytic enzymes from hyperthermophilic microorganisms
Genecor, Palo Alto, CA
Functional genomics analysis of biohydrogen production by
hyperthermophilic microorganisms
Chung-Yuan Christian Univ.,
Taiwan
Functional genomics of stress response in the hyperthermophilic
crenarchaeon Sufolobus solfataricus and role of vapBC ToxinAntitoxin loci in RNA management
Biochemical and biophysical characterization of hyperthermophilic
sugar epimerases and isomerases
Samsung, Seoul, Korea
Ph.D.
2009
(NCSU)
Ph.D.
2009
(NCSU)
Ph.D.
2009
(NCSU)
Ph.D. 2010
(NCSU)
Functional Genomics Analysis of Carbohydrate Conversion to
Biohydrogen by Pure and Mixed Cultures of Hyperthermophilic
Thermotoga Species
Functional genomics analysis of metal mobilization by the extremely
thermoacidophilic archaeon Metallosphaera sedula
Ph.D. 2013
(NCSU)
Ph.D. (NCSU)
Pfizer, Sanford, NC,
Postdoc, Department of
Biomedical Engineering, Duke
University
Muufri, San Francisco, CA
Takeda Pharmaceuticals, RTP,
NC
Carbohydrate utilization in the extremely thermophilic bacterium
Caldicellulosiruptor saccharolyticus
Agrivida, Medford, MA
Functional Genomics Analysis of Extremely Thermophilic
Fermentative Microorganisms from the Archaeal Genus Pyrococcus
and Bacterial Genus Caldicellulosiruptor
VapBC Toxin-Antitoxin Loci in the Extreme Thermoacidophile
Sulfolobus solfataricus: Regulation of and Functional Biochemical
Roles during Thermal Stress Response
Novel S-layer homology domain glycoside hydrolases from
extremely thermophilic Caldicellulosiruptor spp.
Novozymes Biologicals, Inc., RTP,
NC
Biohydrogenesis in the Thermotogales
Novozymes, Franklinton, NC
Microbial Physiology Studies of Hyperthermophilic Microorganisms:
Functional Genomics Analysis of Post-Exponential Growth and
Biochemical Specificity of Ribonucleolytic VapC and HicA Toxins
KBI Pharma, RTP, NC
Fujifilm Diosynth Biotechnologies,
RTP, NC
Pfizer, St. Louis, MO
36. Arpan Mukerjee
IIT Madras
Ph.D. 2014
(NCSU)
37. Hong Lian
East China
U
Ph.D. 2014
(NCSU)
38. Aaron Hawkins
Macalester
College
RoseHullman
Institute
Colorado
State Univ.
University of
Virginia
Notre Dame
Ph.D. 2014
(NCSU)
Ph.D. (NCSU)
Univ. of
Pittsburgh
Highpoint
Univ.
U Florida
Ph.D. (NCSU)
Student
Previous
Training
Period
Research Topic
Ilse I. Blumentals
Johns
Hopkins
Virginia
Tech;
Rutgers
NC State
Duke
South
Carolina
1990-92
1991-97
Hyperthermophilic consortia
Hyperthermophilic glycosidases and DNA polymerases
Animal vaccines, Caracas, VZ
1997-98
1997-2000
1998-99
Xylose isomerases
Biocatalysis in nonaqueous solvents
Hyperthermophilic glycosidases
Novozymes, Franklinton, NC
University of Silicon Lake, China
NC State, Chemistry
39. Andrew Loder
40. Jeffrey Zurawski
41. Garrett Wheaton
42. Jonathan
Conway
43. Benjamin
Zeldes
44. Laura Lee
45. James Counts
Functional genomics and Biochemical characterization of Uranium
biooxidation and stress response in extremely Thermoacidophilic
Metallosphaera species
Transcriptomic and Physiological Analysis of a Recombinant
Pyrococcus furiosus Strain Metabolically Engineered to Produce 3Hydroxypropionate from CO2 and Maltose
Elucidation and Implementation of a Thermophilic Carbon Fixation
Cycle for Electrofuels Metabolic Engineering
Genome Engineering of Extremely Thermophilic Microorganisms for
Biofuels Production
Alexion Pharmaceuticals, New
Haven, CT
Current
Ph.D. (NCSU)
Plant biomass deconstruction by extremely thermophilic
Caldicellulosiruptor species
Heavy metal biooxidation and resistance mechanisms in extremely
thermoacidophilic archaea
Role of S-Layer homology glycoside hydrolases in plant biomass
deconstruction by extremely thermophilic Caldicellulosiruptor
species
Gas to liquid fuels bioconversion using metabolically engineered
hyperthermophiles
Metagenomics strategies for lignofuels at high temperatures
Ph.D. (NCSU)
Microbial Metal Biooxidation by Thermoacidophilic Archaea
Current
Ph.D. (NCSU)
Ph.D. (NCSU)
Ph.D. (NCSU)
School of Public Health, Xiamen
University, China
Novozymes, Franklinton, NC
Current
Current
Current
Current
Current
POSTDOCTORAL STUDENTS/VISITING SCIENTISTS
Guy Duffaud
J. Michael Hess
Hong Chen
Susan Cady
Employment
GSK, Philadelphia, PA
Hak-sung Kim
Stephen Chang
Edward S. Miller, Jr.
Donald E. Ward
Leon Kluskens
Shannon B. Conners
Jason D. Nichols
Sara BlumerSchuette
Yejun Han
Stephanie Bridger
Javier Izquierdo
Carlos Goller
Laura Ott
Thomas Lentz
KAIST,
South Korea
(Professor)
Univ. of
Virginia
NC State
Wake Forest
Univ.,
Wageningen
University
Wageningen
University
(Doctoral
student)
NC State
Duke
University
Michigan
State U
Chinese
Academy of
Sciences,
Univ. of
Illinois-CU
UGA
UMass,
Dartmouth
Univ
Duke Univ.
(Postdoc)
UNC-CH
(Postdoc)
UNC-CH
(Postdoc)
1997-1999
Hyperthermophilic hydantoinases
KAIST, Seoul, Korea
1998-2000
Hyperthermophilic amylases
Medimmune, Gaithersburg, MD
1999-2000
2000-2001
Hyperthermophilic enzymes in transgenic plants
Hyperthermophilic proteases; cDNA microarrays
DuPont, Wilmington, DE
Genencor, Cedar Rapids, IA
2000-2001
Hyperthermophilic pectinases; cDNA microarray studies
Wageningen University; Danisco,
Portugal
2005-2006
2005-2007
Bioinformatics analysis of DNA microarray data
Quorum sensing in hyperthermophiles
SAS Corp., Cary, NC
Syngenta Corp., RTP, NC
2008-2014
Microbial genomics and bioenergy of Caldicellulosiruptor species
2010-2013
Electrofuels
Dept. of Biology, Oakland Univ.,
Oakland, MI
Key Laboratory for Process
Engineering, Chinese Acad. Sci.,
Beijing, China
2013
2014
Pyrococcus furiosis genetics
Metagenomics and genetics of Caldicellulosiruptor species
Asuragen, Austin, TX
Dept. of Biological Sciences,
Hofstra University
2012-2015
Teaching Postdoc, NCSU Biotechnology Program
2012-2015
Teaching Postdoc, NCSU Biotechnology Program
2014-present
Teaching Postdoc, NCSU Biotechnology Program
NCSU BIT Program, Dept. of
Biological Sciences, NCSU
Univ. of Maryland-Baltimore
County
Current