Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Data Source: CSOs from 15 Counties and Lab Highlights Seventeen neonatal deaths reported from seven counties Four maternal deaths reported from four counties Twenty clinically confirmed cases of pertussis including one death was reported from Grand Bassa County Reporting Coverage 100% (745/745) of expected health facilities reported from 90 health districts across 15 counties. 99.5% (741/745) of health facilities submitted timely reports to the district level. 99% (88/90) of health districts submitted timely reports to county level. 100% (15/15) of counties submitted timely reports to the national level. Vaccine Preventable Diseases Measles Eight (8) suspected cases reported. Grand Gedeh (2), Margibi (2), Lofa (1), Bomi (1), Sinoe (1), and Montserrado (1). Specimens were collected from all cases for laboratory confirmation. Four negative results received from the National Reference Laboratory for Epi week 43 and 44. Lofa (2), Montserrado (1) and Bomi (1). Cumulatively, 924 cases have been reported: Lab-confirmed (124), Epi-linked (481), Compatible (137), suspected (33) and discarded (149) (Figure 2). CFR 1% (n=5). Liberia's annualized non-measles febrile rash illness rate stands at 4.3 per 100,000. Grand Cape Mount, Nimba, Rivercess, River Gee and Sinoe Counties are below the target of 2/100,000 (Table 1). Of the total 924 cases reported (Lab confirmed, Epi-linked and suspected), 15% were reportedly previously vaccinated, 39% were unvaccinated, and 46% had unknown vaccination status. 41% of the confirmed and suspected cases are below 5 years. 1 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Table 1. Distribution of Reported Measles Cases by County and Epi-Classification, Liberia, Week 1 - 44, 2016 Lab County Confirmed Bomi 2 Bong 10 Gbarpolu 0 Grand Bassa 20 Grand Cape Mount 0 Grand Gedeh 0 Grand Kru 0 Lofa 4 Margibi 46 Maryland 0 Montserrado 41 Nimba 1 Rivercess 0 River Gee 0 Sinoe 0 NP 0 Liberia 124 Target Achieved EpiLinked 0 49 0 116 0 0 0 29 162 0 104 21 0 0 0 0 481 >=2 Compatible 2 0 5 5 1 14 0 70 0 0 34 5 0 0 0 1 137 Suspected Discarded 3 17 3 13 0 3 0 12 0 0 5 5 0 3 8 10 7 41 0 5 5 29 0 8 0 1 1 0 0 2 0 0 33 149 Below Target Total 24 75 8 153 1 24 3 121 256 5 213 35 1 1 3 1 924 Annualized Non Measles Febrile Rash Illness Rate 20.2 3.9 3.6 5.4 0.0 4.0 5.2 3.6 19.5 3.7 2.6 1.7 1.5 0.0 2.0 4.3 <2 Acute Flaccid Paralysis Two (2) cases reported. Bong (1) and Nimba (1). Cumulatively, 57 cases of AFP have been recorded: Zero confirmed, 49 discarded and 8 pending lab confirmation. As of week 44, the annualized non-polio AFP rate is at 3.6 per 100,000 population in less than 15 years of age (Table 2). Table 2: Non-polio AFP rate/100,000 <15yrs, Liberia, Epi week 1-44, 2016 < 15 years pop County Bomi Bong Gbarpolu Expected Reported Non-Polio AFP Rate % of stool <14days % of NPENT 44700 177210 0.4 1.5 4 6 10.6 4.0 100 100 50% 40% 44312 0.4 1 2.7 100 0% Grand Bassa 117807 100 20% 67527 66562 30775 147124 3 1 3 2 7 3.0 Grand Cape Mount Grand Gedeh Grand Kru Lofa 1.0 0.6 0.6 0.3 1.2 1.8 5.3 7.7 5.6 100 100 100 100 0% 0% 0% 0% Margibi Maryland Montserrado Nimba Rivercess 111552 72237 594229 245519 35492 0.9 0.6 5.0 2.1 0.3 5 2 9 7 1 5.3 3.3 1.8 3.4 3.3 100 100 100 100 100 120% 0% 14% 17% 0% 38000 54410 1847457 0.3 0.5 15.6 2 4 57 6.2 8.7 3.6 100 25 95 0% 50% 32% River-Gee Sinoe Liberia <2 = Non-Polio AFP Rate ≥2 = <80% = Stool adequacy ≥80% = <10% = Non-Polio Enterovirus ≥10% = Silent 2 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Neonatal Tetanus Three (3) cases reported including one (1) death. Montserrado (2) and Grand Bassa (1). The death was reported from Grand Bassa County. Cumulatively, 19 cases have been reported. CFR is 32% (n=6). Viral Hemorrhagic Diseases Ebola Virus Disease (EVD) A total of 121 suspected cases reported (5 alive and 116 dead) of which samples were collected from all. 91 samples tested (12 whole blood and 79 oral swab). 89 samples were tested negative and 2 indeterminate. Overall samples were submitted from 11 counties. Cumulatively, 28,993 alerts have been reported out of which three (3) were confirmed. CFR in confirmed cases is 33.3% (n=1). Table 3. Count of patient samples tested for EVD by county and samples type, Liberia, Epi-week 41 - 44, 2016 Week 41 Week 42 Week 43 Week 44 Whole Blood Oral Swab Whole Blood Oral Swab Whole Blood Oral Swab Whole Blood Oral Swab 17 98 10 126 10 166 12 79 Bomi 3 9 0 4 6 16 1 3 Bong 3 1 1 3 0 4 1 0 Gbarpolu 0 0 0 3 0 1 0 0 Grand Bassa 1 3 0 5 0 3 0 3 Grand Cape Mount 0 1 0 0 0 0 0 0 Grand Gedeh 0 1 0 5 0 1 0 0 Grand Kru 0 1 1 1 0 0 3 0 Lofa 0 1 1 14 0 10 0 6 Margibi 0 2 0 4 0 5 4 2 Maryland 0 0 0 2 1 2 0 0 Montserrado 0 49 1 77 2 86 0 43 Nimba 8 24 5 5 0 28 3 17 Rivercess 0 1 0 2 0 0 0 1 River Gee 0 3 0 0 0 2 0 2 Sinoe 2 2 1 1 0 8 0 2 Unknown 0 0 0 0 0 0 0 0 Geographical Distribution All Counties By County 3 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Lassa Fever One (1) suspected case reported from Grand Bassa County. Cumulatively, 68 cases have been reported, of which 12 confirmed, 29 not a case, 27 suspected (13 awaiting lab confirmation, thus 5 from Epi week 38, 3 for Epi week 39, 2 from Epi week 43 and 1 each from Epi week 40, 42 and 44). CFR for suspected and confirmed cases is 61% and for confirmed cases is 33%. Bong County accounts for 58% of the total confirmed cases. Yellow Fever Three (3) suspected cases reported. Bomi (2) and Grand Kru (1). Cumulatively, 40 cases have been reported, of which twenty-nine (29) tested negative and ten (10) are pending laboratory confirmation. Meningitis Zero case reported. Cumulatively, 26 suspected cases have been reported. Events of Public Health Importance Maternal Mortality Four (4) maternal deaths reported. Bomi (1), Lofa (1) Margibi (1) and Nimba (1). Primary causes of deaths were post-partum hemorrhage (2), ectopic pregnancy and anemia. All of the deaths were reported from health facilities. Cumulatively, 258 maternal deaths have been reported, of which 80% (206) were reported from health facilities and 20% (51) from communities. Annualized maternal mortality ratio is at 173 per 100,000 live births (Table 3). The expected MMR based Demographic (DHS) is on 2013 Health Survey 1072 deaths per 100,000 live births. 4 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Table 4: Cumulative Maternal Deaths Reported by Counties, Liberia, Epi week 1-44, 2016 No. of Maternal Deaths Reported % of Deaths Reported Annualized Maternal Mortality Ratio Bomi 14 5 387 Sinoe 12 5 273 Grand Cape Mount 14 5 256 Grand Kru 6 2 241 Bong 34 13 237 Margibi 19 7 211 River Gee 6 2 209 Maryland 12 5 205 Gbarpolu 7 3 195 Rivercess 5 2 163 Grand Gedeh 8 3 149 Grand Bassa 14 5 147 Nimba 27 10 136 Lofa 16 6 135 64 258 25 100 133 173 Counties Montserrado Liberia Neonatal Mortality Seventeen (17) neonatal deaths were reported. Montserrado (8), Maryland (3), Grand Gedeh (2), Bomi (1), Bong (1), Lofa (1), and Grand Bassa (1). Primary causes of deaths were birth asphyxia (7), neonatal sepsis (5), prolonged labor, hepatitis B and unknown cause. One (1) of the deaths was also reported as Neonatal tetanus attributable death from Grand Bassa. All reported deaths occurred in health facilities. Cumulatively, 450 neonatal deaths have been reported. Annualized neonatal mortality rate is 6 per 1,000 live births. The expected NNMR based on 2013 DHS is 26 deaths per 1,000 live births. 5 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Counties Table 5: Cumulative Neonatal Deaths reported by counties, Liberia, Epi week 1-44, 2016 Cumulative number of % of Deaths Annualized Neonatal Mortality Rate Neonatal Deaths Reported Reported Per 1,000 Live Births Grand Kru River Gee Grand Gedeh Bong Rivercess Maryland Gbarpolu Montserrado Sinoe Lofa Bomi Grand Cape Mount Grand Bassa Margibi Nimba Liberia 19 16 29 71 13 22 13 154 13 31 9 12 20 10 18 450 4 4 6 16 3 5 3 34 3 7 2 3 4 2 4 100 15 11 11 10 8 8 7 6 6 5 5 4 4 2 2 6 Human Exposure to Animal Bites (Suspected Rabies) Nine (9) suspected cases reported. Grand Bassa (3), Montserrado (3), Grand Kru (2) and Margibi (1). Cumulatively, 911 suspected cases have been reported including 8 deaths. CFR is <1%. Laboratory confirmation of rabies is currently unavailable in Liberia. Bloody Diarrhea (Shigellosis) Six (6) suspected cases reported. Margibi (3), Bomi, Grand Kru and Rivercess (1) each. Specimens were collected from all cases for laboratory confirmation. Cumulatively, 322 suspected cases have been reported. Severe Acute Watery Diarrhea (Cholera) Zero case reported. Cumulatively, 147 suspected cases have been reported including 2 deaths. 6 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Whooping Cough (Pertussis) Twenty (20) clinically confirmed cases including (1) death were reported from Grand Bassa. Out of the 20 cases, 8 are males and 12 females. 19 of the cases are less than 5 years. Whooping cough cases were not treated due to antibiotics stock out. Overall, Grand Bassa County has a Penta-3 vaccine <1year coverage of 96% January to September in 2016, however, Campwood district has reported coverage of <0.1%. Public Health Measures National level i. Border counties are encouraged to heighten surveillance activities at PoEs and border communities due to reported outbreak of Rift Valley fever in Niger. ii. Counties encouraged to collect adequate samples for bacteriology testing from all suspected cases of cholera and bloody diarrhea with appropriate specimen collection kits. iii. Preparations are underway for IDSR National Training of Trainers. iv. Counties are encouraged to collect oral swab and report appropriately County Level Information sharing is continuing between Nimba County Health Team and neighboring country (Guinea). Active surveillance ongoing at all border crossings, communities and health facilities. Health education ongoing for Cholera, Measles and other notifiable diseases. Diarrhea Diseases Clinical management of all suspected bloody diarrhea cases reported were prioritized in those counties with cases. Maternal and Neonatal deaths Maternal and newborn death review ongoing in Counties. Vaccine Preventable Diseases Investigation and management of suspected Neonatal Tetanus cases from Montserrado County are ongoing. Human Exposure to Animal Bite Cases of animal bites (suspected human rabies) received post-exposure prophylaxis (anti-rabies vaccine) in affected counties. Lassa fever Patient was isolated and managed. Note Completeness refers to the proportion of health facilities in the country that reported during the week. Timeliness of report is based on the proportion of health facilities that submitted reports on or before 12 noon every Monday to the Division of Disease Prevention and Control (DPC), Ministry of Health (MoH). Non-polio AFP rate is calculated by dividing the number of reported non-polio AFP cases by the expected cases per 100,000 populations under 15 years of age. Non-measles febrile rash illness rate refers to the proportion of discarded cases per 100,000 population. Annualized maternal mortality ratio refers to the maternal mortality ratio of a given period less than one year and it is the number of maternal deaths per 100,000 live births. Epi-linked refers to any suspected case that has not had a specimen taken for serologic confirmation but is linked to a laboratory confirmed case. Compatible case refers to a suspected measles case that is not epidemiologically linked to any lab confirmed case and whose specimen was not tested for laboratory confirmation. Confirmed case refers to a case whose specimen has tested positive on laboratory testing. Case Fatality Rate (CFR) is the proportion of deaths among confirmed cases. 7 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31 - November 6) Epidemiological bulletin published with support of WHO and CDC For comments or questions, please contact Thomas K. Nagbe, PA DIP, BSC, MPH Director, Disease Prevention and Control National IHR Focal Point Ministry of Health Republic of Liberia Email: [email protected] Phone: 0886 937386/0777442444 8 Liberia IDSR Epidemiology Bulletin 2016 Epi Week 44 (October 31- November 6) Cumulative Reported 57 0 322 Cumulative Confirmed 0 0 0 D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 D D 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 A 0 1 0 0 0 0 0 0 0 0 0 4 0 0 0 5 D 9 1 0 2 0 0 0 6 7 6 53 22 1 6 3 116 A 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 3 D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 19 D 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 258 442 18 6 22760 6233 37 3 737 3 10 6 2 1 0 0 0 0 A 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 0 1 2 0 1 0 0 0 1 8 D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 147 2 911 8 66 28 924 7 24 1 0 0 0 0 0 8 4 599 5 0 0 Other Diseases/Events A 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Yellow Fever D 1 1 0 1 0 2 0 1 0 3 8 0 0 0 0 17 A 0 0 0 3 0 0 2 0 1 0 3 0 0 0 0 9 9 VHF (including EVD) D 1 0 0 0 0 0 0 1 1 0 0 1 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Note: A = Alive, D = Dead A D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Neo-Natal Tetanus Measles Lassa Fever Human Exposure to Rabies D Neonatal Mortality A 1 0 0 0 0 0 1 0 3 0 0 0 1 0 0 6 Maternal Mortality D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Meningitis A 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 2 Bomi Bong Gbarpolu Grand Bassa Grand Cape Mount Grand Gedeh Grand Kru Lofa Margibi Maryland Montserrado Nimba Rivercess River Gee Sinoe Total Weekly Cholera 4 8 5 8 5 6 5 6 4 6 7 6 6 4 10 90 Bloody Diarrhoea No. of Health District reported 4 8 5 8 5 6 5 6 4 6 7 6 6 4 10 90 Counties AFP No. of Health Districts Appendix 1: Summary of suspected cases and conditions by County during Epi week 44 and cumulative numbers, Liberia, 2016
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