T he word “botox”, although a registered trade name for a product, elicits various types of reactions when mentioned in conversation. It has become a word of debate, a word often used in gossip and gossip magazines; it can create excitement and also aversion… or even scrutiny. Medical professionals know from multiple loads of research and studies that it is a safe, legally registered and effective product. But, the use (and overuse) of the product by untrained professionals - or even ‘nonprofessionals’ - has contributed to its notorious reputations by some. Slowly but surely, the public has also started realizing it. However, the debate and scrutiny behind it has never deterred eager women and men from having this treatment. Initially used for neurological and muscular conditions from the 50s, the indications for cosmetic uses started to evolve rapidly since its discovery for smile wrinkles in the 80s. New studies and developments still attract attention almost weekly. The recent studies on the effect of the psyche of the patients have attracted a lot of attention from professionals, public and press. Botox =Happy, Shiny People? The first of these thought-provoking studies started in 2006 where it was shown that Botox® reduces depression when injected in the frowning muscles. A trial carried out by Drs Finzi and Wasserman found that treating clinically depressed patients with Botox® on the frown lines of their faces actually got rid of their depression. Nine out of ten patients experienced a resolution of their depression two months after the Botox® treatment on their frown lines. The tenth patient experienced only an improvement in mood. The researchers concluded that Botox® treatment on frown lines may be an effective treatment for patients with major depression who have not responded to routine pharmacologic and psychotherapeutic treatment approaches. A few similar or subsequent studies then followed, explaining this phenomenon. It was rationalized by the facial feedback system where the specific facial expressions that we make affect our feelings and mood. This hypothesis that facial muscle and skin movement may contribute to our mood and emotion was suggested already in the 18th century by German playwright, Gotthold Lessing. It emphasizes the fact that we should integrate the outside (external appearance) to the inside (our soul or emotions). It’s not just the facial feedback that affects the emotions, but the impression that we see in the mirror will affect our feelings and our mood. Literature by Charles Darwin in 1998 also continued on this subject of expressions and intensifying emotions. More literature in the field of the psyche has elaborated about the reduced ability to show expression of grief or anger that reduces the intensity of such emotions. This concept makes it very attractive to go for Botox® injections as this will make all of us happier, less depressed, less aggressive and hopefully reduce our road rage! This does not mean that we should stop doing Botox® around the eyes, but it will probably be wise to reduce the dosage and opt for combination therapy instead. Botox Blues To keep science interesting a new study now in 2013 showed that injecting Botox® in the smile lines will do the opposite! It may induce depression. So which study is true now? Essentially both of the studies are correct. The effect on the mood will depend on which facial muscle or expression is relaxed. For wrinkles around the eyes, Botulinum Toxin (Botox®) is not the exclusive answer. Wrinkles around the eyes do not form just due to an overactive muscle, they form due to a combination of thinning skin, dehydrated skin, loss of volume, gravity and also due to overactive muscle. Therefore, if you are concerned about this possible effect on mood, then it’s not only advisable, but also more ideal, to do various treatments to achieve satisfactory results. This new study headed by Dr Michael Lewis of the School of Psychology, Cardiff, Wales, followed 25 people who had received Botox® for facial lines around the eyes - and examined the idea of facial feedback. Facial feedback, as discussed already, refers to the occurrence of the facial expressions affecting how we feel. Dr. Lewis believes that people became less happy because their “smiling faces” were less “smiley” than before. This was seen in those patients that received Botox® in the ‘smile lines’ to relax this “happy” muscle. Dr. Lewis explained: “The expressions that we make on our face affects the emotions we feel; we smile because we are happy, but smiling also makes us happy. Treatment with drugs like Botox prevents the patient from being able to make this particular expression. For example, those treated for frown lines with Botox are not able to frown as strongly. This interrupts the feedback they would normally get from their face and they feel less sad.” Now what? Practically, what do these studies implicate to doctors and to the patients wanting to reduce wrinkles on the face? These studies are important and revolutionary. Aesthetic and Anti-Ageing Magazine We know that relaxing the frown muscle with Botox® or similar agents are the only effective way to treat frown lines. We also know that it reduces headaches, tension and also depression now. Alternative Solutions Other treatments that are effective for smile or eye wrinkles include fractional laser, mesotherapy, fine line fillers, peelings, LED/ PDT, radiofrequency and also Botox®. These treatments all focus on strengthening the skin around the eye and improving collagen and elastin quality and quantity. Botox® can still be used (and will still be used) for smile wrinkles, but limit the dosage if you are concerned or at risk of depression or being treated for depression. A lower dosage will reduce or even eliminate the effect on your mood. Besides, one also has to bear in mind that this study was conducted on only 25 people. Millions of people have been treated with Botox® for smile wrinkles and the overall impression worldwide has always been that patients are very satisfied and happy due to their improvement of appearance. So, a study of 25 patients is really not sufficient to convince doctors who have seen the multitudes of very happy patients for years. Just the fact that you look better after treatment is more than enough to put you in a good mood! 29
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