Nutrients Macro Micro What is the point of each? What are Nutrients? • Organic* (contain Carbon) & Inorganic molecules in food that are critical to human growth and function – – – – – – Carbohydrates * Lipids (Fats and oils) * Proteins * Vitamins * Minerals Water Divisions of Nutrients • Macronutrients – provide energy to do work* & building blocks for cell structures – Fats, carbs, proteins – Required in large amounts – Broken down and stored or rebuilt • Micronutrients – Required in much smaller quantities – Vitamins and minerals – Used primarily “as-is” Energy of macronutrients • Measured in kilocalories (kcal) = Energy required to raise the temp. of 1g of H2O by 1°C. • Via bomb calorimetry • On food labels, “Calorie” usually means kcal. Energy Density of Two Breakfast Options Compared LOWER ENERGY DENSITY HIGHER ENERGY DENSITY This 450-gram breakfast delivers 500 kcalories, for an energy density of 1.1 (500 kcal ÷ 450 g 1.1 = kcal/g). This 144-gram breakfast also delivers 500 kcalories, for an energy density of 3.5 (500 kcal ÷144 g = 3.5 kcal/g). Carbohydrates • Primary source of Energy during activity (especially for our brain) • C, H and O in ratio of 1:2:1 • Provides 4 kcal/g Fats (Lipids) • Triglycerides, phospholipids • Important source of Energy during rest and low intensity activity • Provide 9 kcal/g (far fewer Oxygens) Proteins • Contain C, H, O & Nitrogen (N)* • Constructed of chains of Amino Acids (AA) • Energy source only in dire need; 4 kcal/g • Important for: – – – – Proteins Bone structure (organic part of bones is protein) Regulating metabolism & fluid balance Repairing muscle & bone Build cells and tissues Clicker Q • Which of the following meals is the most energy dense? 1. One 100g, 500 kcal steak 2. One 180g apple, with 120 kcals & one 170g banana with 200 kcals 3. Two donuts, at 70g & 200 kcal each Table 1-2 Page 9 Calculating Energy of foods • 1 slice bread with 1 tbsp. peanut butter – – – – Carbs: 16g * 4 kcal/g Protein: 7g * 4 kcal/g Fat: 9g * 9 kcal/g Total = 64 kcal = 28 kcal = 81 kcal = 173 kcal Vitamins • Micronutrients (only need a little; e.g. mg, µg) • 1 g = 1,000 mg (milligrams) • 1 mg = 1,000 µg (micrograms) • 1g = 1,000,000 µg Vitamins • Organic compounds that assist in regulating body processes and using E (do not supply E) • 2 types based on solubility – Fat-soluble – Water-soluble Fat-soluble vitamins • Vitamins A, D, E, K • Easily dissolve in fats and oils • Easily stored in adipose tissue (fat cells) throughout the body – Unnecessary to ingest or synthesize these every day Water-soluble vitamins • Vitamins C, B (thiamin, B6, riboflavin, folate, etc.) • Must ingest or synthesize these every day – kidneys filter them from the blood & you excrete them in urine Minerals •Inorganic compounds (no Carbon) •Remain intact (maintain same structure, regardless of their environment) • Major – – – – – – Sodium (Na+) Chloride (Cl-) Potassium (K+) Calcium (Ca2+) Phosphorous (P) Magnesium (Mg2+) • Minor – – – – – – – – Iron Zinc Iodine Selenium Copper Flouride Chromium Molybdenum Minerals • Essential to: – Bone deposition (Ca, P, Mg) – Delivering O2 to cells and removing CO2 (Fe) – Initiating & sustaining muscle contraction (Na, K, Ca) – Propagating nerve impulses (Na, K, Ca) – Fluid balance & blood pressure (Na, K, Cl) H2O ~ 2/3 of total body weight • Dissolves organic and inorganic molecules making a solution (~55% of blood volume is water) • Product or substrate for chemical reactions – Hydrolysis & dehydration synthesis • Extremely Stable – Absorbs and retains heat without changing temp. or state! – Great medium for cooling the body • Lubricates moving parts – Reduces friction • Buffers against pH change Determining Nutrient Intake How much of each nutrient do I need? Dietary Reference Intakes (DRI) • Update traditional Recommended Daily Allowances (RDA) nutritional standards • Establish standards for nutrients without RDA values Dietary Reference Intakes micronutrients macronutrients Dietary Reference Intakes • DRIs consist of 4 values: 1. Estimated Average Requirement (EAR) 2.Recommended Dietary Allowances (RDA) 3.Adequate Intake (AI) 4.Tolerable Upper-Intake Level (UL) Dietary Reference Intakes • Estimated Energy Requirement (EER) • Average energy intake (kcals) needed to maintain energy balance (neither gaining nor losing weight) • Based upon: – – – – – Age Gender Weight Height Level of physical activity EAR & RDA Naive vs. Accurate View of Nutrient Intakes Danger of toxicity Marginal Tolerable Upper Intake Level Safety Safety RDA or AI RDA Marginal Danger Danger of deficiency Naive view Accurate view Estimated Average Requirement Dietary Reference Intakes • Acceptable Macronutrient Distribution Range (AMDR) • Describes the portion of energy intake that should come from each macronutrient Nutrient AMDR Carbohydrate 45 - 65% Fat 20 - 35% Protein 10 - 35% How do nutritionists figure this out? Using the scientific method •Observation •Hypothesis •Prediction •Experiment •Results •Interpretations The Scientific Method Examples of Research Designs EPIDEMIOLOGICAL STUDIES COHORT Heart attack CROSS-SECTIONAL Examine a cultural or ethnic group of people at a single snapshot in time. Attempt to identify factors contributing to health Blood cholesterol Examine a group of people at multiple time steps. Watch for problems that develop & correlate eating patterns that contribute to disease. Examples of Research Designs EXPERIMENTAL STUDIES LABORATORY-BASED ANIMAL STUDIES Feed one group of mice an experimental diet. Others get a control diet. LABORATORY-BASED IN VITRO STUDIES HUMAN INTERVENTION (OR CLINICAL) TRIALS Change eating habits of a group. See if disease symptoms improve. A well- designed experiment • Sample Size • Blind – Placebo • Double-blind – Researcher fallibility • Correlation vs. Causation Your Goal • Create a diet plan that is: – nutritionally adequate – allows you to maintain a healthy weight – support your daily physical activities
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