Your Heart Health Is Too Important to Rely on Just One Number Relying on your cholesterol number alone to know your risk for heart disease may not be enough. LDL particles cause plaque LDL Particle LDL-P This is a measure of the number of LDL particles present in the blood. Cholesterol LDL-C This number reflects the amount of cholesterol carried inside LDL particles. LDL particles are the containers that carry cholesterol in the blood. Two patients. One LDL-C number. Incomplete picture. Two people with the same LDL-C can have different LDL-P. Higher numbers of LDL particles indicate higher risk for heart disease. LDL-P 923 nmol/L LDL-P 1806 nmol/L Charles, 54 LDL-C: 94 mg/dL Edward, 54 LDL-C: 94 mg/dL Plaque progression: More LDL particles = more plaque Low LDL-P ranges* 600 700 800 900 Borderline 1000 1100 1200 1300 1400 High 1500 1600 1700 1800 1900 2000 2100 (nmol/L) * LDL-P range determinations are demonstrated in a representative sampling of the general population (n=5362) enrolled in the Multi-Ethnic Study of Atherosclerosis (MESA).1 Each reporting laboratory should verify the validity of these values for the population it serves. Ask your doctor for LDL-P by NMR Understanding Your Test Results The LDL-Particle testing is more than a cholesterol test. It’s a simple blood test that gives you a direct measure of the particles that cause heart disease. This information can help you and your doctor make informed decisions about the treatment that’s best for you. Use the LDL-Particle test regularly to monitor your progress. Ask your doctor about using the LDL-Particle test by NMR to regularly monitor your progress. Section 1: LDL particle number (LDL-P) LDL-P can range from less than 1000 nmol/L to over 2000 nmol/L. The more LDL particles you have, the higher your risk for heart disease. When your LDL-P is low, your risk may be reduced.2–4 Very-high: LDL-P>2000 nmol/L LDL-P (nmol/L) Borderline-high: LDL-P=1300–1599 nmol/L Moderate: LDL-P=1000–1299 nmol/L Low: LDL-P<1000 nmol/L Low LDL-P ranges* 600 700 800 High: LDL-P=1600–2000 nmol/L 900 Borderline 1000 1100 1200 1300 1400 High 1500 1600 1700 1800 1900 2000 2100 190 200 210 (nmol/L): Section 2: Lipids LDL-C (mg/dL) The lipid panel is a standard cholesterol test. It is made up of four values: LDL-C, HDL-C, triglycerides, and total cholesterol. LDL-C ranges 60 70 80 90 100 110 120 130 140 150 160 170 180 (mg/dL): Date Physician Comments - Treatment Action Plan Repeat LDL-Particle test in References: 1. Mora et al. Atherosclerosis. 2007. 2. McBride PE and Stein JH. Contemporary Diagnosis and Management in Preventive Cardiology. (Humana Press 2006). 3. Cromwell WC et al. Curr Athero Reports. 2004;6:381-7. 4. Otvos JD et al. Am J Cardiol. 2002;90(suppl):22i-29i. 2500 Sumner Blvd. Raleigh, NC 27616 877-547-6837 | www.liposcience.com © 07/2013 LipoScience, Inc. 85-230-05 R1 MC2775-69
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