flyer MML LDL-P - MC2775-69

Your Heart Health Is Too Important
to Rely on Just One Number
Relying on your cholesterol number alone to know your risk for heart disease
may not be enough.
LDL particles cause plaque
LDL
Particle
LDL-P
This is a measure of the
number of LDL particles
present in the blood.
Cholesterol
LDL-C
This number reflects the
amount of cholesterol
carried inside LDL
particles.
LDL particles are the containers
that carry cholesterol in the blood.
Two patients.
One LDL-C number.
Incomplete picture.
Two people with the same
LDL-C can have different LDL-P.
Higher numbers of LDL particles
indicate higher risk for heart
disease.
LDL-P
923 nmol/L
LDL-P
1806 nmol/L
Charles, 54
LDL-C: 94 mg/dL
Edward, 54
LDL-C: 94 mg/dL
Plaque progression: More LDL particles = more plaque
Low
LDL-P
ranges*
600
700
800
900
Borderline
1000
1100
1200
1300
1400
High
1500
1600
1700
1800
1900
2000
2100
(nmol/L)
* LDL-P range determinations are demonstrated in a representative sampling of the general population (n=5362) enrolled in the Multi-Ethnic Study
of Atherosclerosis (MESA).1 Each reporting laboratory should verify the validity of these values for the population it serves.
Ask your doctor for LDL-P by NMR
Understanding Your Test Results
The LDL-Particle testing is more than a cholesterol test. It’s a simple blood test that gives you a direct measure of the
particles that cause heart disease. This information can help you and your doctor make informed decisions about the
treatment that’s best for you. Use the LDL-Particle test regularly to monitor your progress.
Ask your doctor about using the LDL-Particle test by NMR to regularly monitor your progress.
Section 1: LDL particle number (LDL-P)
LDL-P can range from less than
1000 nmol/L to over 2000 nmol/L.
The more LDL particles you have,
the higher your risk for heart
disease. When your LDL-P is low,
your risk may be reduced.2–4
Very-high: LDL-P>2000 nmol/L
LDL-P (nmol/L)
Borderline-high: LDL-P=1300–1599 nmol/L
Moderate: LDL-P=1000–1299 nmol/L
Low: LDL-P<1000 nmol/L
Low
LDL-P
ranges*
600
700
800
High: LDL-P=1600–2000 nmol/L
900
Borderline
1000
1100
1200
1300
1400
High
1500
1600
1700
1800
1900
2000
2100
190
200
210
(nmol/L):
Section 2: Lipids
LDL-C (mg/dL)
The lipid panel is a standard cholesterol test. It is made up of four values:
LDL-C, HDL-C, triglycerides, and total cholesterol.
LDL-C
ranges
60
70
80
90
100
110
120
130
140
150
160
170
180
(mg/dL):
Date
Physician Comments - Treatment Action Plan
Repeat
LDL-Particle
test in
References: 1. Mora et al. Atherosclerosis. 2007. 2. McBride PE and Stein JH. Contemporary Diagnosis and Management in Preventive Cardiology.
(Humana Press 2006). 3. Cromwell WC et al. Curr Athero Reports. 2004;6:381-7. 4. Otvos JD et al. Am J Cardiol. 2002;90(suppl):22i-29i.
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