Meiosis Meiosis Functions to decrease the # of chromosomes by half Human = 46x (diploid number) After Meiosis = 23x (haploid number) Occurs in gametes (sperm/eggs) Overview of Meiosis Two successive nuclear division Produces 4 haploid cells Similar to mitosis Prophase I 1. Homologues (like) chromosomes pair up. They make TETRAD that is composed of two chromatids from each chromosome. 2. Crossing-over may occur at this point. Chromatids break and may be reattached to a different homologous chromosome. Crossing over Metaphase I Tetrads line-up along the equator of the nuclei Spindle fibers attach to the centromere Anaphase I Tetrads separate Independent assortment of homologous chrms. (random separation) Drawn to opposite poles by the spindle fibers Centromere in anaphase I remain intact Telophase I One complete set of chromosomes is in each “future cell”. Prophase II Nuclear envelopes (if they formed during telophase I) dissolve Chromosome condense again Spindle fibers reform Metaphase II spindles moving chromosomes into the middle and attaching to the opposite sides of the centromeres Anaphase II duplicated Telophase II Cytokinesis Cytoplasm divides into the 4 haploid cells Formation of Gametes In animals, meiosis produces haploid reproductive cells called gametes Occurs in the reproductive organs Testes and Ovaries Spermatogenesis Production of sperm cells Diploid cell divides into 4 sperm cells Oogenesis Production of an egg cell Diploid cell divides to form 1 mature egg (receives most of cytoplasm) and 3 eggs that won’t survive called polar bodies Chromosome Numbers in Various Species Carrot 18 Cat 32 Dog 78 Chimpanzee 48 Earthworm 36 Fruit fly 8 Garden pea 20 Horse 64 Lettuce 18 Haploid Numbers? Critical Thinking Develop graphs to illustrate the mass of DNA and chromosome number in each phase of meiosis. Your graphs should be similar to the format shown for mitosis. For telophase, consider only one of the offspring cells at the end of telophase. Let the number 1 represent the mass of DNA that is found in a human ovum. Let the number 1 equal the number of chromosomes found in a human ovum. Mass and Chromosome # in Mitosis 4 3.5 3 2.5 DNA Mass Units Chromosome # 2 1.5 1 0.5 0 Inter Pro Met Ana Telo Cyto
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