ANNUAL MEETING AND AWARDS DINNER
APRIL 9-10, 2014
Omni Shoreham Hotel
Washington, D.C.
Top 10 Clinical Research Achievement Awardees
Recipient of the 2014 Herbert Pardes Clinical Research Excellence Award
Stephan A. Grupp, MD, PhD
Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Director of Translational Research, Center for Childhood Cancer Research at The Children’s Hospital of Philadelphia
“Chimeric antigen receptor-modified T cells for acute lymphoid leukemia”
Recipient of the 2014 Distinguished Clinical Research Award
Daniel J. Rader, MD
Edward S. Cooper, MD/Norman Roosevelt and Elizabeth Meriwether McLure Professor of Medicine and Pharmacology
Perelman School of Medicine, University of Pennsylvania
“The MTP inhibitor lomitapide as a first-in-class new mechanism of therapy for homozygous familial
hypercholesterolemia”
Recipient of the 2014 Distinguished Clinical Research Award
Susan S. Huang, MD, MPH
Associate Professor, Infectious Disease
University of California- Irvine School of Medicine
Medical Director, Epidemiology and Infection Prevention
“Targeted vs. Universal Decolonization to Prevent ICU Infection”
2014 Clinical Research Forum Annual Meeting
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Recipients of the 2014 Clinical Research Achievement Awards
Denise R. Aberle, MD
Professor, Radiology UCLA David Geffen School of Medicine
Professor, Bioengineering UCLA Henry Samueli School of Engineering and Applied Sciences
“Results of the Two Incidence Screenings in the National Lung Screening Trial”
John C. Byrd, MD
D. Warren Brown Chair of Leukemia Research
Professor of Medicine and Medicinal Chemistry, The Ohio State University
“Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia”
Anna Greka, MD, PhD
Assistant Professor of Medicine, Massachusetts General Hospital
“Abatacept in B7-1–positive proteinuric kidney disease”
W. H. Linda Kao, PhD
Professor, Johns Hopkins Bloomberg School of Public Health
“APOL1 risk variants, race, and progression of chronic kidney disease”
Stephen E. Kimmel, MD, MSCE
Professor of Medicine, Cardiovascular Medicine Division, Perelman School of Medicine at the University of Pennsylvania
“A pharmacogenetic versus a clinical algorithm for warfarin dosing”
David R. Nelson, MD
Professor of Medicine, Molecular Genetics and Microbiology
Director, University of Florida Clinical and Translational Science Institute
Associate Dean for Clinical Research
Division of Gastroenterology, Hepatology, and Nutrition
“Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options”
Manikkam Suthanthiran, MD
Stanton Griffis Distinguished Professor of Medicine, Weill Cornell Medical College
Professor of Medicine in Surgery, Weill Cornell Medical College
Professor of Biochemistry, Weill Cornell Medical College
“Urinary–cell mRNA profile and acute cellular rejection in kidney allografts”
2014 Clinical Research Forum Annual Meeting
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Clinical Research Forum Semi-Finalists
Joel S. Finklestein, MD
Massachusetts General Hospital
“Gonadal Steriods and Body Composition, Strength and Sexual Function in Men”
Ali G. Gharvari, MD
Columbia University College of Physicians and Surgeons
“Mutations in DSTYK and Dominant Urinary Tract Malformations”
Gary E. Gold, MD
Stanford University
“Human Cartilage Repair with a Photo reactive Adhesive Hydrogel Composite”
Barton Haynes, MD
Duke University School of Medicine
“Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus”
Stanley L. Hazen, MD, PhD
Case Western Reserve University
“Intestinal micobiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis”
Stavroula Kousteni, PhD
Columbia University College of Physicians and Surgeons
“Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts”
Regina LaRocque, MD, MPH
Massachusetts General Hospital
“Natural selection in a Bangladeshi Population from the Cholera-Endemic Gange River Delta”
Krysztof Palczewski, PhD
Case Western Reserve University
“Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration”
David A. Schwartz, MD
University of Colorado, Denver
“Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis”
Stephanie Seminara, MD
Massachusetts General Hospital
“Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination”
Alice T. Shaw, MD, PhD
Massachusetts General Hospital
“Crizotinib versus chemotherapy in advanced ALK positive lung cancer”
Robert S. Sherwin, MD
Yale University School of Medicine
“Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and
reward pathways”
2014 Clinical Research Forum Annual Meeting
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Jordan W. Smoller, MD, ScD
Massachusetts General Hospital
“Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis”
Rochelle Walensky, MD, MPH
Massachusetts General Hospital
“The cost effectiveness of HIV treatment as prevention in serodiscordant couples”
Joseph C. Wu, MD, PhD
Stanford University
“Abnormal calcium handling properties underlie pathogenesis of familial hypertrophic cardiomyopathy in
patient-specific induced pluripotent stem cells”
Clinical Research Forum 2014 Nominees
Mark E. Anderson, MD, PhD
University of Iowa Carver College of Medicine
“CaMKII: A promising Novel Therapeutic Target for Asthma”
Drucy S. Borowitz, MD
University at Buffalo, School of Medicine and Biomedical Sciences
“Evolution of Pancreatic Function during the First Year of Life in Infants with Cystic Fibrosis”
James Brugarolas, MD, PhD
University of Texas Southwestern Medical Center
“Towards a molecular and functional classification of renal cancer”
Michael Cohen-Wolkowiez, MD, PhD
Duke University School of Medicine
“Determining Population and Developmental Pharmacokinetics of Metronidazole Using Plasma and Dried
Blood Spot Samples from Premature Infants”
Gail L. Daumit, MD, MHS
John Hopkins Schools of Medicine and Public Health
“Randomized Trial of Achieving Healthy Lifestyles in Psychiatric Rehabilitation”
Robert C. Doebele, MD, PhD
University of Colorado
“Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer”
Orlando M. Gutierrez, MD, MMSc
University of Alabama, Birmingham
“Association Between Urinary Albumin Excretion and Coronary Heart Disease in Black vs. White Adults”
Joshua M. Hare, MD, FACC, FAHA
University of Miami Health System
“Adult stem cell therapy for chronic congestive heart failure”
2014 Clinical Research Forum Annual Meeting
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Bankole Johnson, M.B., Ch.B., M. Phil, MD, DSc
University of Maryland School of Medicine
“Topiramate, a drug approved by FDA to treat epilepsy and migraine headaches also could be the first reliable
medication to help treat cocaine dependence”
Rhonda Kost, MD
Rockefeller University
“Development of Validated Research Participant Centered Outcome Measures”
Katherine Luzuriaga, MD
University of Massachusetts Medical School
“Absence of detectable HIV-1 viremia after treatment cessation in an infant”
Vincent C.O. Njar, PhD
University of Maryland School of Medicine
“The Invention of VN/124 (Galeterone) in the Treatment of Castration-Resistant Prostate Cancer”
Anne Louise Oaklander, MD, PhD
Massachusetts General Hospital
“Discovery of a treatable new disease that causes chronic widespread pain and multi-symptom illness in
children and young adults”
Deborah Persaud, MD
Johns Hopkins University
“Very Early Therapy and HIV Remission or Cure in Perinatal Infection”
Patrick Purdon, PhD
Massachusetts General Hospital
“Transformative Technologies for Anesthetic Brain Monitoring in the Operating Room and Intensive Care
Unit”
Antony Rosen, MD
Johns Hopkins University
“Mechanisms underlying the cancer-scleroderma connection”
Jeffrey D. Rothstein, MD, PhD
Johns Hopkins University
“Amyotrophic lateral sclerosis and frontotermporal dementia; pathophysiology and therapy discovery thru
use of induced pluripotent stem cells”
Andrey Rzhetsky, PhD
Pritzker School of Medicine; University of Chicago
“A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk”
Edward M. Schaeffer, MD, PhD
Johns Hopkins University
“Should prostate cancer active surveillance be an option for African-American Men”
2014 Clinical Research Forum Annual Meeting
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Scott M. Thompson, PhD
University of Maryland School of Medicine
“Excitatory synapse dysfunction in the pathology and treatment of major depression”
Willem G. van Panhuis, MD, PhD
University of Pittsburgh
“Contagious diseases in the United States from 1888 to present”
James M. Wilson, MD, PhD
University of Pennsylvania
“Gene therapy to thwart potential influenza pandemic”
Mark J. Zylka, PhD
University of North Carolina at Chapel Hill School of Medicine
“Topoisomerases facilitate transcription of long genes linked to autism”
Thanks to all who submitted nominations for this year’s awards.
48 nominations were received from 26 institutions
Case Western Reserve University
Columbia University
Duke University
Johns Hopkins University
Massachusetts General Hospital
Rockefeller University
Stanford University
The Children’s Hospital of Philadelphia
The Ohio State University
University at Buffalo
University of Alabama, Birmingham
University of California, Irvine
University of California, Los Angeles
University of Chicago
University of Colorado
University of Florida
University of Iowa
University of Maryland
University of Massachusetts
University of Miami
University of North Carolina at Chapel Hill
University of Pennsylvania
University of Pittsburgh
University of Texas Southwestern Medical Center
Weill Cornell Medical College
Yale University
2014 Clinical Research Forum Annual Meeting
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