CEM 252: ORGANIC CHEMISTRY II
SECTIONS 25-36
TUE-THU 8:00 – 9:20 AM
138 CHEMISTRY
SPRING 2017
Instructor:
Class
Coordinator:
Chrysoula Vasileiou
Office: 538B Chemistry
Email: [email protected]
Office hours: Tuesday 9:30 – 10:30 am
Class Website: http://www2.chemistry.msu.edu/courses/cem252/
Nancy Lavrik
Office: 382 Chemistry
Email: [email protected]
Text: David Klein, Organic Chemistry, 2nd Edition, Wiley, ISBN 9781118454312
David Klein, Organic Chemistry, Study Guide, 2nd Edition, Wiley
Course Description:
The second semester of organic chemistry is a natural progression of the material covered
in the first semester. Simply stated, you need a mastery of the concepts and reactions
covered in CEM 251 in order to follow and do well in CEM 252. All students are
encouraged to review the course work presented in CEM 251. In CEM 252, we will begin
with introducing conjugated systems, aromaticity and reactions of aromatic compounds. Next,
we will gradually introduce various functional groups commonly found in organic chemistry. A
large portion of the semester will be spent on the study of carbonyl compounds, their
reactions and properties. The last functional group studied will be amines. We will also look
at the chemistry of carbohydrates and amino acids. The large battery of reactions you have
learned and will learn in CEM 252 should be viewed as tools for synthesis of organic
molecules. You are expected to propose syntheses of molecules based on the mastery
of the reactions you know. This requires you to know your ‘tools’ well in order to use them
for synthesis of compounds. Another important topic of Organic Chemistry is structure
elucidation, which was covered in CEM 251 under the various Spectroscopy chapters. For
this class, you are expected to be able to use spectroscopy, with focus on NMR
spectroscopy, to elucidate the structure of different organic compounds.
Examinations and Grading:
The course grade will be based on your cumulative score of 2/3 best midterms, 4/5 best
quizzes, 2 beSocratic activities and the final exam. Five quizzes are given during recitations
and the best four scores are used towards your final grade. The lowest midterm grade out of
3 midterms will also be dropped. You are allowed to drop quiz and exam lowest grades so as
to accommodate all persons who must miss a scheduled quiz due to religious holidays,
unavoidable personal commitments, illness, etc.
There will be NO make-up quizzes or exams.
University rules stipulate that you will receive a 0.0 for the course if you do not take the final
exam.
2 best Midterms (100 pts each)
4 best Quizzes (25 pts each)
2 beSocratic activities (10 pts each)
520 Posiible Total Points
Final Exam (200 pts)
Total Points
442
416
364
312
Percent
85
80
70
60
Grade
4.0
3.5
3.0
2.5
Total Points
260
234
208
<208
Percent
50
45
40
<40
Grade
2.0
1.5
1.0
0.0
Policy Regarding Academic Dishonesty:
Academic dishonesty of any kind will not be tolerated in this course. Please see the following
website for information regarding Michigan State University’s policy regarding academic
dishonesty:
https://www.msu.edu/~ombud/academic-integrity/index.html
Regrading of Exams:
Hourly exams will be returned during the regularly scheduled recitation following the exam.
Any regrading requests must be made at that time to the recitation instructor. Except for
obvious addition errors, no exam which has left the recitation room with a student will be
considered for regrading. Final exams are not returned but are kept by your instructor.
Posting of Exam Scores:
After the exams have been graded and recorded, you can check the cemscores website for
your grade: cemscores.msu.edu or from the MSU home page or the chemistry department
home page enter just the word cemscores into the address bar area (do not include www in
front of it). You can also check the grades of your quizzes in this website.
Recitations:
This is your chance to ask the questions you were not able to ask in lecture. Your teaching
assistants are a great source of information and help. Attendance is very important if you
want to learn organic chemistry. Listening to lecture does not teach you the problem solving
skills you need. The goal of recitation is to guide you through problems, answer questions
regarding the lectures, and teach you how to talk organic chemistry.
Recitations are devoted to answering questions, assisting students in problem solving,
giving quizzes, and returning hourly examinations (Remember, there will be no make-up
quizzes given). Since your recitation instructor keeps course records, it is critical that you
know your recitation instructor's name and your recitation section number by the time of the
first recitation/quiz. This will ensure that your scores are properly recorded. Due to limited
space in recitation rooms, you are asked to attend the recitation you are enrolled in.
For extra help, you may see any CEM 252 TA during scheduled office hours. Please do not
enter graduate labs at other times since dangerous chemicals are always present and
potentially dangerous experiments may be in progress.
A list of all recitations for this class, the names of all the TAs and their office hours will be
posted on the class website.
Recitations begin on Monday, January 9.
Problem Sets:
Suggested problems from the book for each chapter are attached at the end of this
syllabus. They will not be collected and graded, however, I strongly suggest that you attempt
the problems to gauge your understanding of the material and test your readiness for the
exams. I discourage you from looking at the solutions manual without attempting to do the
problems. Try to use your text and notes to see if you can solve the problems. Remember, if
you are not able to solve the problems, it probably means that you have not understood the
subject matter. Go back and read, do not just look up the answer! It is much more beneficial
for you to struggle through the problem and learn, as opposed to looking at the solution
manual and see how it is done.
In addition, throughout the semester several problem sets will be posted on the CEM252
web site, (http://www2.chemistry.msu.edu/courses/cem252/), along with their solutions.
These problem sets will not be graded but you are strongly advised to study them and make
sure you know how to solve them. Recitations and office hours is a good time to discuss
these problems and ask for help.
How much should you study?
A conservative estimate is about 4 hours per each lecture. Begin from day one. It is
important to keep up with the lectures. More than any course, organic chemistry depends on
previously discussed material. It is very easy to fall behind.
TENTATIVE LECTURE AND EXAM SCHEDULE
Date
Topic
Reading Assignment
January 10
January 12
January 17
January 19
January 24
January 26
January 31
February 2
Conjugated π-systems
“ “
“ “
Aromatics
“ “
“ “
Alcohols, Phenols
“ “
Chapters 17
“ “
“ “
Chapter 18/19
“ “
“ “
Chapter 13
“ “
February 7
February 9
“ “
1 Midterm
“ “
Chapters 16-18
February 14
Aldehydes, Ketones
Chapter 20
February 16
“ “
“ “
February 21
“ “
“ “
February 23
“ “
“ “
February 28
Acids, Acid Derivatives
Chapter 21
March 2
“ “
“ “
March 6-10
Spring Break
----
March 14
Acids, Acid Derivatives
Chapter 21
March 16
st
nd
2
Midterm
Chapters 13-14, 20
March 21
Enols, Enolates
Chapter 22
March 23
“ “
“ “
March 28
“ “
“ “
March 30
“ “
“ “
April 4
Amines
Chapter 23
April 6
“ “
“ “
April 11
Carbohydrates
Chapter 24
April 13
“ “
“ “
“ “
“ “
April 20
3 Midterm
Chapters 21-23
April 25
Amino Acids
Chapter 25
April 27
“ “
“ “
April 18
rd
FINAL EXAM: TUESDAY, MAY 2, 12:45 – 2:45 PM, COMPREHENSIVE
(The final exam for this class is listed under COMMON FINALS)
Suggested Practice Problems from the book:
Please pay extra attention to the “SkillBuilderReview”, at the end of each chapter. It is a
very good summary of the skills and/or reactions you need to know from each chapter.
Learning organic chemistry is best achieved through working problems. Below is a list
of suggested problems for each chapter. It s highly recommended to work through the
in chapter problem as one reads the chapter. One should attempt to solve as many
problems as possible. Problems assigned in the book will be supplemented with
problem set handouts in class. Book problems and problem sets are the best indication
of how exam questions will be formulated. In addition to the book problems intergraded
in the text, here is a list of suggested problems from the end of each chapter.
Chapter 17: 17.32; 17.33; 17.43; 17.44; 17.50; 17.56
Chapter 18: 18.28; 18.29; 18.34; 18.36; 18.37; 18.38; 18.40; 18.59; 18.60
Chapter 19: 19.43; 19.44; 19.45; 19.46; 19.47; 19.48; 19.49; 19.50; 19.53; 19.54;
19.56; 19.57; 19.58; 19.68; 19.69
Chapter 13: 13.30; 13.31; 13.33; 13.34; 13.35; 13.37; 13.38; 13.39; 13.40; 13.41;
13.44; 13.45; 13.46; 13.47; 13.48; 13.49; 13.50; 13.53; 13.56
Chapter 20: 20.44; 20.45; 20.51; 20.54; 20.56; 20.58; 20.60; 20.61; 20.63; 20.66
Chapter 21: 21.39; 21.41; 21.42; 21.45; 21.48; 21.49; 21.50; 21.51; 21.52; 21.53;
21.54; 21.55; 21.57; 21.65; 21.73; 21.74; 21.80
Chapter 22: 22.57; 22.59; 22.60; 22.63; 22.67; 22.68; 22.71; 22.73; 22.76; 22.77;
22.78; 22.79; 22.83; 22.87; 22.89; 22.90; 22.91; 22.92; 22.93; 22.94; 22.95; 22.97
Chapter 23: 23.39; 23.40; 23.41; 23.42; 23.43; 23.44; 23.50; 23.51; 23.54; 23.59; 23.70
Chapter 24: 24.42; 24.45; 24.46; 24.49; 24.51; 24.56; 24.69